## Wed Feb 18 21:23:46 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158310_bin.15.fa -m mmseqs --output SRR25158310_bin.15 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158310_bin.15 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158310_k127_1007792_4	1121451.DESAM_20599	4.048e-12	69.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,42S18@68525|delta/epsilon subdivisions,2WN9J@28221|Deltaproteobacteria,2MAMV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
SRR25158310_k127_1007792_2	269799.Gmet_1369	6.187e-42	163.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158310_k127_1007792_1	1232683.ADIMK_0637	8.204e-142	453.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,469VN@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158310_k127_1007792_0	1191523.MROS_0859	0.0	1226.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158310_k127_1007792_3	323261.Noc_1255	5.335e-22	99.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158310_k127_1025424_2	351160.RCIX1575	1.173e-24	107.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,2N98X@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158310_k127_1025424_0	313628.LNTAR_20488	9.76e-91	308.0	COG0548@1|root,COG0548@2|Bacteria	2|Bacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158310_k127_1025424_1	497964.CfE428DRAFT_2167	2.365e-34	136.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158310_k127_102663_0	1122194.AUHU01000008_gene3355	3.703e-121	405.0	COG1502@1|root,COG1502@2|Bacteria,1MXA6@1224|Proteobacteria,1RZZ7@1236|Gammaproteobacteria,469BP@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158310_k127_102663_1	469381.Dpep_2045	3.597e-94	320.0	COG0628@1|root,COG0628@2|Bacteria,3T9W6@508458|Synergistetes	508458|Synergistetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158310_k127_102663_2	717785.HYPMC_2976	8.724e-77	267.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,3N6IM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158310_k127_102663_3	1403819.BATR01000028_gene933	2.511e-42	162.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia,2IU5A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Type III pantothenate kinase	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158310_k127_1045874_0	667014.Thein_1424	2.793e-168	537.0	COG0466@1|root,COG0466@2|Bacteria,2GICM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158310_k127_1045874_2	1499967.BAYZ01000097_gene4350	6.343e-89	316.0	COG4826@1|root,COG4826@2|Bacteria,2NQVB@2323|unclassified Bacteria	2|Bacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SRR25158310_k127_1045874_5	1232410.KI421424_gene1667	5.779e-34	144.0	28HEC@1|root,2Z7QS@2|Bacteria,1QGH3@1224|Proteobacteria,42WU7@68525|delta/epsilon subdivisions,2WT75@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1045874_1	1123274.KB899410_gene3382	4.182e-157	515.0	COG0475@1|root,COG0475@2|Bacteria,2J603@203691|Spirochaetes	203691|Spirochaetes	GPT	PFAM Sodium hydrogen exchanger family	napA-1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2
SRR25158310_k127_1045874_4	744872.Spica_2569	8.194e-45	168.0	COG1762@1|root,COG1762@2|Bacteria,2J7FM@203691|Spirochaetes	203691|Spirochaetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
SRR25158310_k127_1045874_6	926566.Terro_4379	9.818e-21	94.0	COG0776@1|root,COG0776@2|Bacteria,3Y50P@57723|Acidobacteria,2JJJ5@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158310_k127_1045874_3	1461693.ATO10_07767	9.765e-50	181.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TQYW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158310_k127_1047118_1	545695.TREAZ_3177	6.833e-47	174.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
SRR25158310_k127_1047118_0	1444711.CCJF01000005_gene831	1.317e-155	501.0	COG0187@1|root,COG0187@2|Bacteria,2JFGD@204428|Chlamydiae	204428|Chlamydiae	L	DNA topoisomerase (ATP-hydrolyzing)	parE	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158310_k127_1048442_5	340.xcc-b100_0977	3.76e-11	64.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1X5DM@135614|Xanthomonadales	135614|Xanthomonadales	P	abc transporter, permease	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158310_k127_1048442_3	40215.BBOS01000017_gene2510	1.036e-52	199.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,3NKVC@468|Moraxellaceae	1236|Gammaproteobacteria	P	Bacterial extracellular solute-binding protein	modA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iECO111_1330.ECO111_0773,iPC815.YPO1145	SBP_bac_11
SRR25158310_k127_1048442_4	243164.DET1150	6.323e-33	130.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	fdx4	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158310_k127_1048442_2	290318.Cvib_1350	3.129e-154	497.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1FDRX@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM nitrogenase cofactor biosynthesis protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Fer4_14,Nitro_FeMo-Co,Radical_SAM
SRR25158310_k127_1048442_1	290512.Paes_1633	1.231e-169	543.0	COG2710@1|root,COG2710@2|Bacteria,1FDC9@1090|Chlorobi	1090|Chlorobi	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
SRR25158310_k127_1048442_0	545695.TREAZ_3219	3.773e-202	639.0	COG2710@1|root,COG2710@2|Bacteria,2J714@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the NifD NifK NifE NifN family	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
SRR25158310_k127_1059110_4	1056820.KB900674_gene2557	1.945e-18	94.0	COG0745@1|root,COG1196@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1SXQE@1236|Gammaproteobacteria,2PPTH@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154,HATPase_c,HisKA,Response_reg
SRR25158310_k127_1059110_0	1123508.JH636440_gene2544	2.906e-102	345.0	COG2195@1|root,COG2195@2|Bacteria,2IXPR@203682|Planctomycetes	203682|Planctomycetes	E	Peptidase M20	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158310_k127_1059110_2	667632.KB890187_gene3080	1.483e-29	128.0	COG0730@1|root,COG0730@2|Bacteria,1RCVI@1224|Proteobacteria,2WG87@28216|Betaproteobacteria,1K031@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158310_k127_1059110_3	194439.CT0091	1.452e-26	115.0	COG2062@1|root,COG2062@2|Bacteria,1FE6K@1090|Chlorobi	1090|Chlorobi	T	PFAM Phosphoglycerate mutase	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158310_k127_1059110_1	436114.SYO3AOP1_0528	4.295e-37	149.0	COG0703@1|root,COG0703@2|Bacteria,2G46N@200783|Aquificae	200783|Aquificae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158310_k127_1063266_2	247490.KSU1_C0392	1.03e-87	302.0	COG0466@1|root,COG0466@2|Bacteria,2IYNA@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158310_k127_1063266_0	518766.Rmar_1523	8.148e-193	614.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1FITT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158310_k127_1063266_1	247639.MGP2080_02825	2.02e-107	357.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158310_k127_1066111_2	1121344.JHZO01000004_gene1758	3.476e-44	166.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158310_k127_1066111_3	748449.Halha_1818	1.436e-31	128.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WAQ6@53433|Halanaerobiales	186801|Clostridia	K	TIGRFAM transcriptional regulator, Rrf2 family	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158310_k127_1066111_0	552811.Dehly_0382	1.173e-135	438.0	COG0031@1|root,COG0031@2|Bacteria,2G5PG@200795|Chloroflexi,34CIG@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158310_k127_1066111_1	216142.LT40_05480	6.04e-47	177.0	COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative porin	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_5
SRR25158310_k127_1066957_1	247634.GPB2148_786	7.037e-11	64.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1J5GM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158310_k127_1066957_0	2340.JV46_24480	1.946e-261	813.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1J4J8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	ybaL	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158310_k127_1072088_0	472759.Nhal_2664	8.697e-72	251.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1WWFW@135613|Chromatiales	135613|Chromatiales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158310_k127_1072088_1	323261.Noc_0839	2.444e-66	235.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,1RRII@1236|Gammaproteobacteria,1WZ3P@135613|Chromatiales	135613|Chromatiales	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158310_k127_1072088_3	472759.Nhal_2666	3.099e-41	164.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1WZG8@135613|Chromatiales	135613|Chromatiales	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158310_k127_1072088_5	76114.ebA5156	1.378e-11	73.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,2KWVW@206389|Rhodocyclales	206389|Rhodocyclales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158310_k127_1072088_4	237368.SCABRO_03165	3.457e-29	121.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158310_k127_1072088_2	237368.SCABRO_03166	5.068e-56	202.0	COG0811@1|root,COG0811@2|Bacteria,2IZ3U@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158310_k127_1075888_0	1304885.AUEY01000014_gene3345	3.622e-66	235.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,42PBB@68525|delta/epsilon subdivisions,2WKBZ@28221|Deltaproteobacteria,2MIZ8@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158310_k127_1075888_1	278957.ABEA03000091_gene694	1.459e-26	119.0	COG3271@1|root,COG3271@2|Bacteria,46U2C@74201|Verrucomicrobia,3K8HI@414999|Opitutae	414999|Opitutae	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
SRR25158310_k127_1083052_1	1230342.CTM_01155	1.408e-54	201.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,36FAU@31979|Clostridiaceae	186801|Clostridia	H	Lipoate-protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
SRR25158310_k127_1083052_3	1123274.KB899413_gene821	2.155e-17	84.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950	PTS-HPr
SRR25158310_k127_1083052_0	377629.TERTU_0959	5.493e-189	594.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,2PN5S@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Fructose-bisphosphate aldolase class-II	fbaA	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z4263	F_bP_aldolase
SRR25158310_k127_1083052_2	313628.LNTAR_14082	7.754e-39	151.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	Thioredoxin_7
SRR25158310_k127_1096437_2	1042375.AFPL01000051_gene188	1.279e-51	187.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	synthase	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
SRR25158310_k127_1096437_0	227377.CBU_0609	1.497e-86	297.0	COG1577@1|root,COG1577@2|Bacteria,1RIKN@1224|Proteobacteria,1S678@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	GHMP kinases N terminal domain	-	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158310_k127_1096437_1	1122599.AUGR01000012_gene876	6.005e-63	228.0	COG1577@1|root,COG1577@2|Bacteria,1NF04@1224|Proteobacteria,1RPXQ@1236|Gammaproteobacteria,1XIA1@135619|Oceanospirillales	135619|Oceanospirillales	I	GHMP kinases C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158310_k127_1096437_3	398720.MED217_08175	1.637e-09	60.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,1HXZR@117743|Flavobacteriia,2XIYS@283735|Leeuwenhoekiella	976|Bacteroidetes	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158310_k127_1098002_5	1304885.AUEY01000003_gene515	6.45e-06	52.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MHS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
SRR25158310_k127_1098002_4	765952.PUV_12800	3.584e-10	64.0	COG2217@1|root,COG2217@2|Bacteria,2JFND@204428|Chlamydiae	204428|Chlamydiae	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158310_k127_1098002_2	1131269.AQVV01000008_gene916	1.991e-95	325.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR25158310_k127_1098002_3	1348114.OM33_14205	4.256e-16	80.0	2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,1S7DW@1236|Gammaproteobacteria,2Q2EZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
SRR25158310_k127_1098002_1	1177154.Y5S_00586	3.124e-97	321.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,1RREG@1236|Gammaproteobacteria,1XJ9N@135619|Oceanospirillales	135619|Oceanospirillales	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158310_k127_1098002_0	1125863.JAFN01000001_gene1462	4.571e-303	949.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158310_k127_1098002_6	593907.Celgi_0133	0.000131	49.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158310_k127_1098148_2	331113.SNE_A22520	2.515e-34	137.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7,HTH_18
SRR25158310_k127_1098148_0	272624.lpg2566	3.054e-130	421.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,1JEXA@118969|Legionellales	118969|Legionellales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
SRR25158310_k127_1098148_1	1121921.KB898707_gene794	3.223e-39	147.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S9EI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	lcrS	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158310_k127_1106167_0	1094980.Mpsy_2748	4.039e-140	457.0	COG0513@1|root,arCOG00558@2157|Archaea,2XUS4@28890|Euryarchaeota,2N99K@224756|Methanomicrobia	224756|Methanomicrobia	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158310_k127_1106167_1	237368.SCABRO_00505	1.616e-92	312.0	COG2996@1|root,COG2996@2|Bacteria,2J1Y7@203682|Planctomycetes	203682|Planctomycetes	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
SRR25158310_k127_1106167_2	596151.DesfrDRAFT_1007	1.784e-33	131.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,42TW6@68525|delta/epsilon subdivisions,2WQNT@28221|Deltaproteobacteria,2MCKC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM translation initiation factor SUI1	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR25158310_k127_1107496_0	555079.Toce_1427	1.651e-150	492.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158310_k127_1109709_0	314230.DSM3645_10432	3.862e-174	552.0	COG0166@1|root,COG0166@2|Bacteria,2IXRA@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158310_k127_1110317_1	316067.Geob_1233	2.221e-81	282.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,43TZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
SRR25158310_k127_1110317_0	665571.STHERM_c13210	6.128e-164	530.0	COG3604@1|root,COG3604@2|Bacteria,2J5TK@203691|Spirochaetes	203691|Spirochaetes	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158310_k127_111405_1	388413.ALPR1_14484	6.878e-18	85.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta
SRR25158310_k127_111405_2	471853.Bcav_0812	7.829e-09	64.0	2EE4N@1|root,337ZA@2|Bacteria,2IMPW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_111405_0	1541959.KQ51_00282	6.652e-158	530.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppsA	-	2.7.9.2,6.5.1.3	ko:K01007,ko:K14415	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PEP-utilizers,PPDK_N
SRR25158310_k127_111405_3	926569.ANT_05600	0.0009972	48.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1135944_0	658086.HMPREF0994_02452	3.389e-154	512.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158310_k127_1135944_1	497964.CfE428DRAFT_5019	2.147e-65	229.0	COG0077@1|root,COG0077@2|Bacteria,46U8V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158310_k127_1141292_4	1443125.Z962_12125	9.778e-35	138.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,36ICK@31979|Clostridiaceae	186801|Clostridia	P	Chromate	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158310_k127_1141292_3	754027.HMPREF9554_01912	5.784e-38	149.0	COG2059@1|root,COG2059@2|Bacteria,2J7W5@203691|Spirochaetes	203691|Spirochaetes	P	Chromate transport protein	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158310_k127_1141292_1	313628.LNTAR_24059	1.386e-158	516.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158310_k127_1141292_5	1396141.BATP01000006_gene5449	5.324e-09	64.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia,2IUQI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SRR25158310_k127_1141292_6	443254.Marpi_1095	4.199e-08	57.0	COG0268@1|root,COG0268@2|Bacteria,2GDFA@200918|Thermotogae	200918|Thermotogae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158310_k127_1141292_2	497964.CfE428DRAFT_2117	4.301e-44	175.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158310_k127_1141292_0	278957.ABEA03000106_gene1848	1.043e-220	695.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,3K7NB@414999|Opitutae	414999|Opitutae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158310_k127_1141421_3	452637.Oter_4044	5.941e-122	413.0	COG0323@1|root,COG3170@1|root,COG0323@2|Bacteria,COG3170@2|Bacteria,46SG5@74201|Verrucomicrobia,3K76S@414999|Opitutae	414999|Opitutae	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158310_k127_1141421_4	485915.Dret_1682	2.578e-43	162.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2WM6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SRR25158310_k127_1141421_0	177439.DP0394	2.115e-168	539.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2MIT8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158310_k127_1141421_1	743722.Sph21_2418	5.554e-126	408.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
SRR25158310_k127_1141421_2	880073.Calab_0629	1.577e-125	409.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158310_k127_1142034_2	998088.B565_3991	2.17e-09	65.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158310_k127_1142034_0	452637.Oter_0242	1.62e-44	171.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158310_k127_1142034_1	1547437.LL06_04335	3.004e-11	74.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,43HEZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR25158310_k127_1146683_5	1321786.HMPREF1992_01352	3.4e-17	82.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158310_k127_1146683_2	935948.KE386494_gene649	2.255e-49	181.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,42G74@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158310_k127_1146683_3	1565314.OA34_01415	3.289e-40	154.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2YNVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1038	DHquinase_II
SRR25158310_k127_1146683_4	272134.KB731324_gene4188	2.607e-39	153.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HAGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158310_k127_1146683_1	439235.Dalk_0814	1.092e-78	271.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MJ7B@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158310_k127_1146683_0	756272.Plabr_2924	1.451e-83	282.0	COG0504@1|root,COG0504@2|Bacteria,2IXNE@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158310_k127_1150022_0	1403819.BATR01000191_gene6559	4.321e-174	557.0	COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia,2ITJQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158310_k127_1150022_4	997346.HMPREF9374_2821	8.208e-35	137.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,27BZV@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal protein L7/L12 dimerisation domain	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158310_k127_1150022_5	1118059.CAHC01000020_gene1134	1.519e-27	118.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WCJV@538999|Clostridiales incertae sedis	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158310_k127_1150022_1	1123070.KB899254_gene1251	3.3e-81	276.0	COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia,2ITZ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158310_k127_1150022_2	382464.ABSI01000011_gene2686	5.897e-62	215.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,2IUAM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158310_k127_1150022_3	1156937.MFUM_210037	3.339e-58	207.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,37GI4@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158310_k127_1150022_6	338966.Ppro_0667	3.725e-08	57.0	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,43VQU@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158310_k127_1153413_2	314230.DSM3645_28652	1.086e-07	55.0	COG1508@1|root,COG1508@2|Bacteria,2IXGU@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158310_k127_1153413_0	96561.Dole_3027	1.974e-64	230.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria,2MJ1B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158310_k127_1153413_1	95619.PM1_0221545	2.014e-10	74.0	COG4625@1|root,COG4625@2|Bacteria,1R9VZ@1224|Proteobacteria,1SIX9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
SRR25158310_k127_1155589_0	1307759.JOMJ01000003_gene22	4.359e-49	196.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2M8CS@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM SNF2-related protein	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
SRR25158310_k127_1156403_1	265072.Mfla_1747	8.636e-07	54.0	2ENVQ@1|root,33GGS@2|Bacteria,1NGVT@1224|Proteobacteria,2VY6X@28216|Betaproteobacteria,2KND3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
SRR25158310_k127_1156403_0	575540.Isop_3259	3.012e-103	342.0	COG0423@1|root,COG0423@2|Bacteria,2IY4R@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158310_k127_1160985_0	243231.GSU3447	1.063e-67	234.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,43URV@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158310_k127_1160985_2	404380.Gbem_0992	1.395e-29	118.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	ypeB	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
SRR25158310_k127_1160985_3	1121406.JAEX01000002_gene916	7.733e-24	106.0	COG2204@1|root,COG2204@2|Bacteria,1NBTR@1224|Proteobacteria,42V7Q@68525|delta/epsilon subdivisions,2WR8M@28221|Deltaproteobacteria,2MBT7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158310_k127_1160985_1	688246.Premu_2630	2.741e-44	164.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,2FMMZ@200643|Bacteroidia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158310_k127_1163929_2	32024.JMTI01000016_gene368	1.503e-31	126.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iIT341.HP0824	Thioredoxin
SRR25158310_k127_1163929_1	192952.MM_3268	2.954e-43	164.0	COG0778@1|root,arCOG00288@2157|Archaea,2XYGC@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
SRR25158310_k127_1163929_0	517418.Ctha_1954	2.062e-180	577.0	COG2265@1|root,COG2265@2|Bacteria,1FDAZ@1090|Chlorobi	1090|Chlorobi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158310_k127_1170638_2	1485545.JQLW01000006_gene516	5.067e-28	120.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria	1224|Proteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158310_k127_1170638_0	1001530.BACE01000014_gene1149	5.328e-50	192.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XTKI@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158310_k127_1170638_1	436114.SYO3AOP1_1739	1.024e-47	178.0	COG0491@1|root,COG0491@2|Bacteria,2G479@200783|Aquificae	200783|Aquificae	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158310_k127_1176268_0	1033802.SSPSH_002752	4.484e-37	150.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S7A2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1176268_1	1033802.SSPSH_002752	1.545e-36	150.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S7A2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1181428_1	953739.SVEN_6920	3.847e-42	162.0	COG1175@1|root,COG1175@2|Bacteria,2GKYS@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158310_k127_1181428_0	1280390.CBQR020000054_gene1062	4.943e-88	310.0	COG0395@1|root,COG0395@2|Bacteria,1V1TN@1239|Firmicutes,4HU3Z@91061|Bacilli,26RTQ@186822|Paenibacillaceae	91061|Bacilli	G	Sugar ABC transporter permease	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158310_k127_1181428_2	575540.Isop_2050	1.34e-21	94.0	COG0366@1|root,COG0366@2|Bacteria,2IXJN@203682|Planctomycetes	203682|Planctomycetes	G	alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
SRR25158310_k127_119422_5	1231057.AMGD01000020_gene3258	3.803e-12	73.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,26EJ6@186818|Planococcaceae	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158310_k127_119422_2	1156937.MFUM_170024	8.398e-90	299.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,37G7G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158310_k127_119422_1	717605.Theco_2582	1.999e-163	524.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,26T95@186822|Paenibacillaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158310_k127_119422_0	1308866.J416_12072	5.368e-187	591.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,47040@74385|Gracilibacillus	91061|Bacilli	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158310_k127_119422_4	102125.Xen7305DRAFT_00007460	4.513e-23	101.0	2C93P@1|root,33GTQ@2|Bacteria,1GAV2@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_119422_3	1480694.DC28_11295	1.447e-41	156.0	COG1816@1|root,COG1816@2|Bacteria	2|Bacteria	F	deaminase activity	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158310_k127_1202231_0	1123226.KB899290_gene318	4.192e-69	243.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli,26RX9@186822|Paenibacillaceae	91061|Bacilli	S	esterase	estA	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
SRR25158310_k127_1202231_1	1307759.JOMJ01000003_gene784	3.254e-43	166.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2M9CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158310_k127_1202443_0	1379281.AVAG01000012_gene1490	6.56e-130	422.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2MGD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158310_k127_1202443_1	525897.Dbac_0662	6.989e-59	211.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WJ8G@28221|Deltaproteobacteria,2M7Y8@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158310_k127_1206963_0	720554.Clocl_2886	3.408e-136	441.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158310_k127_1206963_1	240016.ABIZ01000001_gene2902	5.121e-52	207.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia,2ITY2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcription elongation factor, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158310_k127_1217353_2	1287116.X734_24155	8.282e-09	57.0	COG2827@1|root,COG2827@2|Bacteria,1N04N@1224|Proteobacteria,2UCN4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	excinuclease ABC	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
SRR25158310_k127_1217353_3	266264.Rmet_5200	1.138e-07	59.0	COG0346@1|root,COG0346@2|Bacteria,1QVY4@1224|Proteobacteria,2VY37@28216|Betaproteobacteria,1K58Q@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158310_k127_1217353_0	194439.CT1655	3.718e-23	104.0	COG3411@1|root,COG3411@2|Bacteria,1FFA6@1090|Chlorobi	1090|Chlorobi	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1217353_1	1089550.ATTH01000001_gene1139	2.513e-17	93.0	COG2203@1|root,COG3829@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
SRR25158310_k127_1218805_1	247490.KSU1_C0525	5.944e-29	134.0	2DN50@1|root,32VJ4@2|Bacteria,2J04A@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SRR25158310_k127_1218805_0	321327.CYA_2880	3.674e-32	135.0	COG3225@1|root,COG3225@2|Bacteria,1G0JN@1117|Cyanobacteria,1GZQ1@1129|Synechococcus	1117|Cyanobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
SRR25158310_k127_1219150_0	498761.HM1_2112	3.047e-98	330.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158310_k127_1219150_1	269799.Gmet_1842	6.938e-46	177.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158310_k127_1219150_2	264201.pc0322	9.909e-29	117.0	COG0481@1|root,COG0481@2|Bacteria,2JFFF@204428|Chlamydiae	204428|Chlamydiae	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158310_k127_1225201_3	1121405.dsmv_2440	1.533e-06	53.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,2MJFJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	frdC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158310_k127_1225201_1	1123279.ATUS01000001_gene1722	5.254e-168	533.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158310_k127_1225201_0	83406.HDN1F_09550	5.579e-273	851.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158310_k127_1225201_2	876044.IMCC3088_2314	6.099e-131	425.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2
SRR25158310_k127_1226424_3	1396141.BATP01000006_gene5499	1.583e-12	68.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,2IU0V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACCA
SRR25158310_k127_1226424_2	32049.SYNPCC7002_A0307	4.063e-38	145.0	COG1539@1|root,COG1539@2|Bacteria,1G93A@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	5.1.99.7	ko:K07589	ko00790,map00790	-	R11082	RC01479	ko00000,ko00001,ko01000	-	-	-	FolB
SRR25158310_k127_1226424_1	1499967.BAYZ01000145_gene6207	2.062e-48	182.0	COG1028@1|root,COG1028@2|Bacteria,2NQVU@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158310_k127_1226424_0	478741.JAFS01000002_gene444	3.915e-76	269.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,37G9H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
SRR25158310_k127_1227092_0	313628.LNTAR_04636	3.268e-201	642.0	COG0046@1|root,COG0046@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS,AIRS_C,GATase_5
SRR25158310_k127_1227303_1	269797.Mbar_A0860	4.148e-117	390.0	COG3635@1|root,arCOG01696@2157|Archaea,2XU1U@28890|Euryarchaeota,2N95W@224756|Methanomicrobia	224756|Methanomicrobia	G	phosphoglycerate mutase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158310_k127_1227303_0	653733.Selin_1261	3.738e-149	493.0	COG0513@1|root,COG0513@2|Bacteria	2|Bacteria	L	helicase activity	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158310_k127_1227303_2	903818.KI912268_gene824	1.494e-14	75.0	COG2344@1|root,COG2344@2|Bacteria,3Y805@57723|Acidobacteria	57723|Acidobacteria	K	Putative DNA-binding protein N-terminus	-	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158310_k127_122794_1	497964.CfE428DRAFT_1568	8.203e-71	250.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
SRR25158310_k127_122794_2	563192.HMPREF0179_02166	0.0006717	49.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MDHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
SRR25158310_k127_122794_0	247490.KSU1_C0073	1.43e-111	376.0	COG1328@1|root,COG1328@2|Bacteria	2|Bacteria	F	CTP reductase activity	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
SRR25158310_k127_1228169_1	324925.Ppha_1952	5.633e-60	210.0	COG2710@1|root,COG2710@2|Bacteria,1FDEX@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM nitrogenase molybdenum-iron protein alpha chain	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
SRR25158310_k127_1228169_0	319225.Plut_1532	3.011e-226	707.0	COG2710@1|root,COG2710@2|Bacteria,1FDJS@1090|Chlorobi	1090|Chlorobi	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
SRR25158310_k127_1228169_2	1121403.AUCV01000016_gene4413	5.909e-23	100.0	2C06Z@1|root,3335S@2|Bacteria,1NI0C@1224|Proteobacteria,42X3F@68525|delta/epsilon subdivisions,2WT33@28221|Deltaproteobacteria,2MP40@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Nif11 domain	-	-	-	-	-	-	-	-	-	-	-	-	Nif11
SRR25158310_k127_1228169_3	545695.TREAZ_3224	8.215e-18	89.0	2EJZ1@1|root,33DPM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1228169_4	290317.Cpha266_0910	3.535e-08	57.0	2EBB0@1|root,335BP@2|Bacteria,1FEA8@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1241697_1	1123393.KB891318_gene2164	9.39e-106	348.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,1KRXP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2,S4
SRR25158310_k127_1241697_2	1151116.Q7S_22255	8.927e-20	97.0	COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,1RRDC@1236|Gammaproteobacteria,3FG6V@34037|Rahnella	1236|Gammaproteobacteria	S	Haloacid dehalogenase-like hydrolase	yihX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050308	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158310_k127_1241697_0	1210884.HG799465_gene12093	1.851e-135	445.0	COG0326@1|root,COG0326@2|Bacteria,2IYC7@203682|Planctomycetes	203682|Planctomycetes	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
SRR25158310_k127_1242635_2	111780.Sta7437_1338	3.91e-12	67.0	COG0589@1|root,COG0589@2|Bacteria,1G75A@1117|Cyanobacteria,3VKQZ@52604|Pleurocapsales	1117|Cyanobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158310_k127_1242635_0	247490.KSU1_C0857	6.787e-127	413.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158310_k127_1242635_1	237368.SCABRO_01880	2.622e-102	342.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158310_k127_1242635_4	59374.Fisuc_1435	0.0007376	51.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
SRR25158310_k127_1242635_3	1123242.JH636434_gene5412	1.801e-09	63.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158310_k127_1243457_3	861208.AGROH133_10214	2.509e-70	269.0	COG5434@1|root,COG5434@2|Bacteria,1MYC2@1224|Proteobacteria,2U0PY@28211|Alphaproteobacteria,4BKQ2@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
SRR25158310_k127_1243457_0	1246626.BleG1_1042	4.815e-203	653.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158310_k127_1243457_4	177439.DP2396	1.315e-42	160.0	COG2731@1|root,COG2731@2|Bacteria,1N5B5@1224|Proteobacteria,42TJQ@68525|delta/epsilon subdivisions,2WR4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
SRR25158310_k127_1243457_2	91464.S7335_2022	1.095e-72	253.0	COG2203@1|root,COG2203@2|Bacteria,1G3XH@1117|Cyanobacteria,1H3W6@1129|Synechococcus	1117|Cyanobacteria	T	COG2203 FOG GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_4,Response_reg
SRR25158310_k127_1243457_1	497964.CfE428DRAFT_4705	2.285e-102	347.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158310_k127_124397_0	313628.LNTAR_19542	4.468e-158	506.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	uxaC	GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528	UxaC
SRR25158310_k127_124397_1	305700.B447_03623	1.961e-37	143.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,2KUD7@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158310_k127_1246939_2	221027.JO40_09695	2.1e-47	178.0	COG0475@1|root,COG0475@2|Bacteria,2J5WC@203691|Spirochaetes	203691|Spirochaetes	P	Sodium hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Na_H_Exchanger
SRR25158310_k127_1246939_1	754027.HMPREF9554_01324	7.14e-64	225.0	COG1762@1|root,COG3311@1|root,COG1762@2|Bacteria,COG3311@2|Bacteria,2J5KE@203691|Spirochaetes	203691|Spirochaetes	G	DNA-binding protein PTS system, IIA component	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
SRR25158310_k127_1246939_0	1121403.AUCV01000052_gene2571	1.387e-168	542.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria,2MPWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158310_k127_1249838_0	1432055.GLUCORHAEAF1_07495	3.317e-181	582.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2JX0B@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158310_k127_1249838_1	1168065.DOK_10046	3.042e-79	267.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1J50N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG0302 GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158310_k127_1249838_2	748727.CLJU_c32220	1.01e-10	70.0	COG5523@1|root,COG5523@2|Bacteria,1VCPB@1239|Firmicutes,24N8D@186801|Clostridia,36IJR@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
SRR25158310_k127_1254591_0	350688.Clos_0007	1.525e-180	574.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158310_k127_1254591_1	331113.SNE_A14110	6.572e-119	396.0	COG0187@1|root,COG0187@2|Bacteria,2JFF2@204428|Chlamydiae	204428|Chlamydiae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158310_k127_1267344_1	385682.AFSL01000041_gene278	3.822e-79	271.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,2FMM4@200643|Bacteroidia,3XJWZ@558415|Marinilabiliaceae	976|Bacteroidetes	I	Putative undecaprenyl diphosphate synthase	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158310_k127_1267344_0	646529.Desaci_4686	2.726e-142	463.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,260YE@186807|Peptococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158310_k127_1272549_1	945713.IALB_2895	6.482e-80	277.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
SRR25158310_k127_1272549_0	945713.IALB_2896	1.546e-136	441.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158310_k127_127279_5	1124780.ANNU01000005_gene2456	1.176e-15	78.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
SRR25158310_k127_127279_4	243090.RB6770	2.526e-28	115.0	COG0211@1|root,COG0211@2|Bacteria,2J04T@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158310_k127_127279_1	697281.Mahau_1510	2.282e-106	355.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158310_k127_127279_2	313628.LNTAR_21455	1.649e-84	312.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase,YHYH
SRR25158310_k127_127279_0	595460.RRSWK_00701	9.882e-137	469.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,FGE-sulfatase,Lactamase_B_2,PD40,Peptidase_S9
SRR25158310_k127_127279_3	485916.Dtox_0908	3.628e-70	244.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,2600U@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158310_k127_1273521_0	686340.Metal_1844	1.33e-236	747.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XE0B@135618|Methylococcales	135618|Methylococcales	H	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158310_k127_1273521_1	56780.SYN_00176	6.01e-236	745.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	homocysteine S-methyltransferase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
SRR25158310_k127_1273521_4	298386.PBPRA2362	7.491e-36	140.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,1S4I5@1236|Gammaproteobacteria,1XXNS@135623|Vibrionales	135623|Vibrionales	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158310_k127_1273521_2	497964.CfE428DRAFT_1797	1.004e-98	337.0	COG0008@1|root,COG0008@2|Bacteria,46SJ3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158310_k127_1273521_3	1122963.AUHB01000004_gene3166	1.699e-45	170.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2TTN7@28211|Alphaproteobacteria,3702B@31993|Methylocystaceae	28211|Alphaproteobacteria	F	Phosphoribosyl transferase domain	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158310_k127_1273521_5	880073.Calab_1358	1.275e-16	88.0	COG1074@1|root,COG1074@2|Bacteria,2NPH8@2323|unclassified Bacteria	2|Bacteria	L	PD-(D/E)XK nuclease superfamily	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K03406,ko:K03582,ko:K03657,ko:K03658,ko:K07464,ko:K16898,ko:K19465	ko02020,ko02030,ko03420,ko03430,ko03440,map02020,map02030,map03420,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02048,ko03029,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158310_k127_1287983_2	1396418.BATQ01000106_gene5316	5.032e-41	156.0	COG1327@1|root,COG1327@2|Bacteria,46TAA@74201|Verrucomicrobia,2IU77@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158310_k127_1287983_0	497964.CfE428DRAFT_1790	8.333e-196	632.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158310_k127_1287983_1	497964.CfE428DRAFT_1789	1.78e-106	353.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158310_k127_1295306_7	240016.ABIZ01000001_gene2648	6.38e-31	124.0	COG0144@1|root,COG0144@2|Bacteria,46TY0@74201|Verrucomicrobia,2ITWQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158310_k127_1295306_4	1178537.BA1_09246	5.461e-39	155.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,1ZC5R@1386|Bacillus	91061|Bacilli	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158310_k127_1295306_1	887327.HMPREF0476_1120	1.449e-80	278.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,2KQ2S@206351|Neisseriales	206351|Neisseriales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158310_k127_1295306_2	290397.Adeh_2370	6.067e-64	227.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158310_k127_1295306_3	240016.ABIZ01000001_gene3616	5.15e-62	220.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158310_k127_1295306_0	478741.JAFS01000001_gene2175	6.26e-194	619.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,37G4S@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	LMWPc,LacAB_rpiB,SHMT
SRR25158310_k127_1295306_6	697281.Mahau_0044	6.328e-31	127.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158310_k127_1295306_5	1123371.ATXH01000005_gene2137	1.014e-31	132.0	COG0009@1|root,COG0009@2|Bacteria,2GGWC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158310_k127_1295306_8	264201.pc1225	8.893e-25	111.0	COG1198@1|root,COG1198@2|Bacteria,2JFSI@204428|Chlamydiae	204428|Chlamydiae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Helicase_C,ResIII
SRR25158310_k127_1307159_1	96561.Dole_0068	1.149e-47	183.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2MHPA@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158310_k127_1307159_0	497964.CfE428DRAFT_4464	2.338e-265	842.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158310_k127_1307853_1	1403819.BATR01000069_gene2093	4.239e-92	311.0	COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia,2ITSA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Fumarate reductase flavoprotein C-term	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158310_k127_1307853_4	497964.CfE428DRAFT_4444	1.937e-07	58.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1307853_0	1125699.HMPREF9194_00174	5.693e-113	375.0	COG0216@1|root,COG0216@2|Bacteria,2J5KY@203691|Spirochaetes	203691|Spirochaetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158310_k127_1307853_3	596324.TREVI0001_1088	1.865e-25	107.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158310_k127_1307853_2	497964.CfE428DRAFT_4766	6.297e-70	244.0	COG1039@1|root,COG1039@2|Bacteria,46UTB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158310_k127_1308988_1	445973.CLOBAR_02720	7.025e-90	299.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,25QQ0@186804|Peptostreptococcaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158310_k127_1308988_2	457570.Nther_1199	1.467e-84	307.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia	186801|Clostridia	O	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158310_k127_1308988_11	1262914.BN533_00044	1.256e-12	74.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4H4HY@909932|Negativicutes	909932|Negativicutes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158310_k127_1308988_0	889378.Spiaf_0243	2.654e-148	482.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
SRR25158310_k127_1308988_8	398767.Glov_0916	4.936e-24	102.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria	1224|Proteobacteria	S	Zinc finger cdgsh-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158310_k127_1308988_5	1042376.AFPK01000014_gene228	1.517e-40	158.0	COG0637@1|root,COG0637@2|Bacteria,4NQ18@976|Bacteroidetes,1I2P0@117743|Flavobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158310_k127_1308988_4	349741.Amuc_0554	9.748e-60	213.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,2IU98@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Ribonuclease HII	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158310_k127_1308988_6	394221.Mmar10_2899	6.96e-39	147.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,43XR3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158310_k127_1308988_3	1121090.KB894685_gene3697	9.958e-79	269.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158310_k127_1308988_9	289376.THEYE_A0819	6.924e-21	93.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158310_k127_1308988_10	411471.SUBVAR_05358	1.416e-20	96.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3WJSQ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158310_k127_1308988_7	1123058.KB894231_gene1242	1.013e-24	108.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158310_k127_1310563_1	313628.LNTAR_04636	1.144e-111	373.0	COG0046@1|root,COG0046@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS,AIRS_C,GATase_5
SRR25158310_k127_1310563_0	1232410.KI421418_gene2284	1.101e-167	535.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,43S81@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158310_k127_1317929_6	1123277.KB893244_gene5102	9.859e-11	69.0	2CYFR@1|root,32T44@2|Bacteria,4P6IN@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158310_k127_1317929_4	1227500.C494_14046	3.416e-28	126.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158310_k127_1317929_2	562743.JH976434_gene1836	6.552e-43	166.0	2DBV7@1|root,2ZB9P@2|Bacteria,1UBN2@1239|Firmicutes,4HEYF@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158310_k127_1317929_1	1250232.JQNJ01000001_gene2262	1.683e-43	164.0	arCOG06733@1|root,313GU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1317929_0	574375.BAGA_18610	6.667e-108	359.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158310_k127_1317929_3	316274.Haur_1728	4.508e-32	130.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
SRR25158310_k127_1319957_0	644282.Deba_1855	6.171e-07	62.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
SRR25158310_k127_1324323_2	96561.Dole_0109	1.406e-25	116.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria,2MNJG@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
SRR25158310_k127_1324323_1	177437.HRM2_01390	2.363e-90	306.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria,2MIAP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158310_k127_1324323_0	525897.Dbac_2319	1.393e-146	475.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2WITG@28221|Deltaproteobacteria,2M7Z2@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,Orn_DAP_Arg_deC
SRR25158310_k127_1324323_3	1313304.CALK_0095	8.034e-24	104.0	COG2509@1|root,COG2509@2|Bacteria	2|Bacteria	H	5-formyltetrahydrofolate cyclo-ligase activity	IV02_08645	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2
SRR25158310_k127_1337085_2	313612.L8106_03237	4.717e-07	58.0	COG1452@1|root,COG1452@2|Bacteria,1FZYB@1117|Cyanobacteria,1H7KU@1150|Oscillatoriales	1117|Cyanobacteria	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	DUF3769,LptC,OstA
SRR25158310_k127_1337085_3	1121957.ATVL01000008_gene4232	1.01e-05	57.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR25158310_k127_1337085_0	439235.Dalk_5106	2.147e-231	725.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WJVC@28221|Deltaproteobacteria,2MINJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158310_k127_1337085_1	1190603.AJYD01000018_gene1807	1.648e-114	373.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XTU0@135623|Vibrionales	135623|Vibrionales	C	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
SRR25158310_k127_1342586_0	237368.SCABRO_02612	3.802e-309	966.0	COG0495@1|root,COG0495@2|Bacteria,2IX36@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158310_k127_1344995_0	138119.DSY1312	5.696e-220	701.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158310_k127_13484_0	1408823.AXUS01000008_gene2281	3.303e-51	188.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,25S6G@186804|Peptostreptococcaceae	186801|Clostridia	J	Queuosine biosynthesis protein	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158310_k127_1362032_0	497964.CfE428DRAFT_0879	1.063e-58	216.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR25158310_k127_1362032_1	5059.CADAFLAP00004076	1.206e-07	59.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3QJDH@4890|Ascomycota,20MG3@147545|Eurotiomycetes,3SC0N@5042|Eurotiales	4751|Fungi	M	NACHT, and Ankyrin domain protein	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	AAA_22,Ank_2,Ank_4,NACHT
SRR25158310_k127_1364719_0	56780.SYN_01425	2.77e-74	268.0	COG4206@1|root,COG4206@2|Bacteria,1QUJF@1224|Proteobacteria,43BJH@68525|delta/epsilon subdivisions,2WM36@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158310_k127_1364719_2	481448.Minf_2256	1.379e-20	98.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,37GXU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	STAS domain	rsbS	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158310_k127_1364719_1	41431.PCC8801_0023	6.719e-37	145.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,3KFU7@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158310_k127_1367107_1	349741.Amuc_0999	3.385e-09	61.0	COG1544@1|root,COG1544@2|Bacteria,46VGU@74201|Verrucomicrobia,2IU7I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158310_k127_1367107_0	1156937.MFUM_200037	9.191e-97	321.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,37FW2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
SRR25158310_k127_1367107_2	378806.STAUR_1610	8.218e-08	62.0	COG1934@1|root,COG1934@2|Bacteria,1Q8US@1224|Proteobacteria,437GV@68525|delta/epsilon subdivisions,2X2PY@28221|Deltaproteobacteria,2Z09H@29|Myxococcales	28221|Deltaproteobacteria	S	OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRR25158310_k127_1370645_0	1121921.KB898706_gene3166	7.094e-141	456.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,2PN48@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158310_k127_1370645_1	1449126.JQKL01000026_gene2441	1.183e-66	229.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,267WP@186813|unclassified Clostridiales	186801|Clostridia	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158310_k127_1371248_0	1168034.FH5T_21285	7.929e-132	436.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,2FNU3@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158310_k127_1371248_1	158190.SpiGrapes_1176	3.088e-63	224.0	COG1132@1|root,COG1132@2|Bacteria,2J5W8@203691|Spirochaetes	203691|Spirochaetes	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158310_k127_1371525_1	585503.HMPREF7545_0367	7.979e-75	263.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes	909932|Negativicutes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158310_k127_1371525_0	313628.LNTAR_00350	6.608e-201	636.0	COG0173@1|root,COG0173@2|Bacteria	2|Bacteria	J	aspartate-tRNA(Asn) ligase activity	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158310_k127_1371541_1	904314.SEVCU012_1583	6.787e-09	58.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,4GX3P@90964|Staphylococcaceae	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU03790	AA_kinase,ACT,ACT_7
SRR25158310_k127_1371541_0	289376.THEYE_A1986	1.933e-115	386.0	COG0460@1|root,COG0460@2|Bacteria,3J0G1@40117|Nitrospirae	40117|Nitrospirae	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158310_k127_1381921_1	574087.Acear_1047	9.399e-81	276.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WAB1@53433|Halanaerobiales	186801|Clostridia	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158310_k127_1381921_0	278957.ABEA03000019_gene1923	1.842e-135	442.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158310_k127_1387067_0	247490.KSU1_C0073	2.452e-148	481.0	COG1328@1|root,COG1328@2|Bacteria	2|Bacteria	F	CTP reductase activity	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
SRR25158310_k127_1387067_1	1158338.JNLJ01000001_gene222	1.174e-37	148.0	COG1180@1|root,COG1180@2|Bacteria,2G49Z@200783|Aquificae	200783|Aquificae	O	Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158310_k127_1399193_0	94122.Shewana3_2665	1.385e-66	230.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,2Q9GY@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158310_k127_1399193_2	452637.Oter_1498	4.091e-18	91.0	COG1546@1|root,COG1546@2|Bacteria,46XV4@74201|Verrucomicrobia,3K8CF@414999|Opitutae	414999|Opitutae	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
SRR25158310_k127_1399193_1	518766.Rmar_0739	9.315e-47	171.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1FJU9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158310_k127_1404431_0	1487921.DP68_13550	1.033e-25	113.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158310_k127_1404431_1	632245.CLP_4388	1.835e-15	87.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158310_k127_1409184_2	1469245.JFBG01000003_gene434	3.039e-29	121.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1WY0F@135613|Chromatiales	135613|Chromatiales	P	PFAM Rhodanese-like	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158310_k127_1409184_1	472759.Nhal_0026	9.769e-47	173.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
SRR25158310_k127_1409184_0	395493.BegalDRAFT_1769	1.003e-87	299.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,45ZQK@72273|Thiotrichales	72273|Thiotrichales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158310_k127_1415947_3	511062.GU3_04820	3.019e-13	70.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1Y4J1@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158310_k127_1415947_0	1123008.KB905696_gene2812	3.748e-152	495.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,22VX7@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158310_k127_1415947_1	1499967.BAYZ01000155_gene629	7.229e-128	419.0	COG0116@1|root,COG0116@2|Bacteria	2|Bacteria	L	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
SRR25158310_k127_1415947_2	1996.JOFO01000041_gene5062	2.711e-38	147.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4EJCJ@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158310_k127_1415947_4	497964.CfE428DRAFT_5496	1.576e-12	77.0	COG0553@1|root,COG0553@2|Bacteria,46TSJ@74201|Verrucomicrobia	74201|Verrucomicrobia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
SRR25158310_k127_1418225_2	1121904.ARBP01000006_gene3981	1.528e-10	64.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158310_k127_1418225_1	1123070.KB899251_gene665	8.104e-36	148.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,2ITNJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158310_k127_1418225_3	1094558.ME5_01098	8.055e-05	49.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,2VADS@28211|Alphaproteobacteria,48U41@772|Bartonellaceae	28211|Alphaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158310_k127_1418225_0	1121403.AUCV01000044_gene36	7.132e-129	417.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2MJ56@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158310_k127_1422524_0	481448.Minf_0926	1.55e-64	243.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,37FV2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158310_k127_1422524_1	502025.Hoch_5770	1.129e-08	57.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,4379J@68525|delta/epsilon subdivisions,2X2DI@28221|Deltaproteobacteria,2Z06I@29|Myxococcales	28221|Deltaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
SRR25158310_k127_1433744_3	748671.LCRIS_01652	1.615e-22	98.0	2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1433744_4	1347393.HG726024_gene3108	7.944e-10	60.0	29ZMA@1|root,30MMU@2|Bacteria,4PAD9@976|Bacteroidetes,2FZG7@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1433744_5	408672.NBCG_05699	7.562e-06	48.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1433744_7	3880.AES92424	2.557e-05	46.0	2DSTA@1|root,2S6GN@2759|Eukaryota,37W7A@33090|Viridiplantae,3GK4J@35493|Streptophyta	35493|Streptophyta	S	Protein of unknown function (DUF2647)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2647
SRR25158310_k127_1433744_0	497964.CfE428DRAFT_5595	0.0	1620.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158310_k127_1433744_2	1403819.BATR01000191_gene6558	1.047e-77	262.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,2ITYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158310_k127_1433744_1	313628.LNTAR_19662	3.414e-263	827.0	COG0085@1|root,COG0085@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158310_k127_1435696_0	1167006.UWK_01652	1.37e-101	335.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,2MMSY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158310_k127_1435696_1	382464.ABSI01000003_gene4211	8.284e-33	131.0	2CBEP@1|root,32RT7@2|Bacteria,46W59@74201|Verrucomicrobia,2IV0U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1438619_2	497964.CfE428DRAFT_5378	1.892e-64	226.0	COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158310_k127_1438619_0	313628.LNTAR_14042	1.72e-177	571.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
SRR25158310_k127_1438619_3	1996.JOFO01000003_gene6082	1.334e-44	172.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4EGGP@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-(Acyl carrier protein) reductase	inhA	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158310_k127_1438619_1	387092.NIS_0703	6.528e-101	334.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158310_k127_1444716_0	391612.CY0110_25346	1.122e-117	400.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,3KKU4@43988|Cyanothece	1117|Cyanobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158310_k127_1444716_2	179408.Osc7112_5097	7.286e-98	333.0	COG4191@1|root,COG4191@2|Bacteria,1G2US@1117|Cyanobacteria,1H8YF@1150|Oscillatoriales	1117|Cyanobacteria	T	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158310_k127_1444716_1	706587.Desti_1823	4.951e-117	404.0	COG0745@1|root,COG3290@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158310_k127_1452592_0	926692.AZYG01000051_gene1842	1.403e-84	297.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WAIF@53433|Halanaerobiales	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158310_k127_1452592_2	926561.KB900617_gene2310	3.762e-23	102.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WATQ@53433|Halanaerobiales	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158310_k127_1452592_1	324925.Ppha_1175	5.832e-26	110.0	COG0353@1|root,COG0353@2|Bacteria,1FDRD@1090|Chlorobi	1090|Chlorobi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158310_k127_1455836_1	637905.SVI_2946	1.589e-120	394.0	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,2Q9H8@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM aminotransferase class I and II	avtA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.66	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	-	R01215	RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	iEKO11_1354.EKO11_0154,iEcSMS35_1347.EcSMS35_3895	Aminotran_1_2
SRR25158310_k127_1455836_0	1268237.G114_02379	1.02e-125	409.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1Y3ED@135624|Aeromonadales	135624|Aeromonadales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
SRR25158310_k127_1455836_2	675817.VDA_002449	3.593e-94	315.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria,1Y35P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
SRR25158310_k127_1455836_3	983544.Lacal_2196	3.463e-09	68.0	COG4232@1|root,COG4232@2|Bacteria,4PMN2@976|Bacteroidetes,1IJVD@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
SRR25158310_k127_147446_1	717785.HYPMC_3137	1.786e-36	152.0	COG0438@1|root,COG0438@2|Bacteria,1MVKB@1224|Proteobacteria,2U53J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_147446_0	176299.Atu4813	7.507e-58	218.0	28KF0@1|root,2ZA18@2|Bacteria,1R7MD@1224|Proteobacteria,2U08E@28211|Alphaproteobacteria,4B7UH@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_147446_3	521011.Mpal_0827	2.779e-23	111.0	arCOG02210@1|root,arCOG02210@2157|Archaea,2XXFV@28890|Euryarchaeota,2NA7K@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM polysaccharide biosynthesis protein	-	-	-	ko:K19418	-	-	-	-	ko00000,ko02000	-	-	-	Polysacc_synt
SRR25158310_k127_1478412_1	497964.CfE428DRAFT_1881	9.029e-67	248.0	COG0815@1|root,COG0815@2|Bacteria,46SPW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158310_k127_1478412_0	648996.Theam_0242	8.425e-121	397.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158310_k127_1478412_2	1123508.JH636440_gene2806	1.436e-64	229.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158310_k127_1478412_3	452637.Oter_2851	2.86e-28	131.0	COG1450@1|root,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,3K7FR@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158310_k127_1489772_1	1357275.AVEL02000076_gene2023	6.744e-66	231.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1Z4YJ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158310_k127_1489772_0	497964.CfE428DRAFT_3932	5.498e-161	522.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR25158310_k127_1489772_2	429009.Adeg_1611	1.187e-64	235.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,42EMA@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158310_k127_1498929_1	1122212.AULO01000011_gene557	1.55e-93	312.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,1XIV8@135619|Oceanospirillales	135619|Oceanospirillales	F	dihydroorotase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158310_k127_1498929_0	1537915.JU57_07240	1.269e-125	422.0	COG1242@1|root,COG4121@1|root,COG1242@2|Bacteria,COG4121@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2YN2U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30,Radical_SAM,Radical_SAM_C
SRR25158310_k127_1498929_2	1122201.AUAZ01000002_gene1010	4.202e-53	191.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934	DAHP_synth_1
SRR25158310_k127_1506820_0	926561.KB900621_gene2788	1.819e-107	358.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3WA68@53433|Halanaerobiales	186801|Clostridia	F	TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
SRR25158310_k127_1506820_1	484770.UFO1_0427	2.875e-74	256.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4H41C@909932|Negativicutes	909932|Negativicutes	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158310_k127_1513940_1	398767.Glov_2107	2.458e-49	181.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158310_k127_1513940_0	382464.ABSI01000013_gene1531	9.918e-63	219.0	COG0756@1|root,COG0756@2|Bacteria,46WRH@74201|Verrucomicrobia	74201|Verrucomicrobia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158310_k127_1513940_2	1121468.AUBR01000001_gene497	6.997e-42	163.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158310_k127_1515937_3	927704.SELR_20500	3.151e-06	52.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4H1Y2@909932|Negativicutes	909932|Negativicutes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158310_k127_1515937_1	1121346.KB899826_gene382	4.018e-23	102.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158310_k127_1515937_2	240016.ABIZ01000001_gene498	3.531e-20	100.0	2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
SRR25158310_k127_1515937_0	1125863.JAFN01000001_gene383	2.905e-31	134.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	eight transmembrane protein EpsH	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
SRR25158310_k127_1517507_1	478749.BRYFOR_05901	7.318e-14	81.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158310_k127_1517507_0	661367.LLO_1696	2.6e-54	198.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1JE0H@118969|Legionellales	118969|Legionellales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	ybbO	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158310_k127_1524783_2	477974.Daud_1346	5.658e-10	64.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,2602S@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
SRR25158310_k127_1524783_0	1123242.JH636435_gene1857	9.392e-162	532.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
SRR25158310_k127_1524783_1	316067.Geob_3360	1.087e-84	298.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158310_k127_1541636_0	234267.Acid_2266	3.649e-107	365.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
SRR25158310_k127_1541636_1	313628.LNTAR_05306	5.864e-75	260.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SRR25158310_k127_1549993_5	373994.Riv7116_4050	9.045e-24	106.0	COG0394@1|root,COG0394@2|Bacteria,1G8I1@1117|Cyanobacteria,1HNIR@1161|Nostocales	1117|Cyanobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158310_k127_1549993_0	378806.STAUR_2893	5.416e-173	560.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2YU1P@29|Myxococcales	28221|Deltaproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
SRR25158310_k127_1549993_4	1232410.KI421413_gene674	1.719e-37	143.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,43UVT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158310_k127_1549993_6	1458462.JNLK01000001_gene1795	3.951e-13	71.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,27PJB@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158310_k127_1549993_2	1384049.CD29_16500	1.514e-76	267.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,3IWN8@400634|Lysinibacillus	91061|Bacilli	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
SRR25158310_k127_1549993_1	338963.Pcar_1502	3.952e-161	519.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2WK2D@28221|Deltaproteobacteria,43SVC@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
SRR25158310_k127_1549993_3	1156937.MFUM_1020047	3.105e-39	154.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,37G6B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	MacB-like periplasmic core domain	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158310_k127_1568341_2	596315.HMPREF0634_1208	7.887e-29	115.0	COG1592@1|root,COG1592@2|Bacteria,1UMCU@1239|Firmicutes	1239|Firmicutes	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SRR25158310_k127_1568341_0	926561.KB900617_gene1210	7.248e-120	398.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WBER@53433|Halanaerobiales	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
SRR25158310_k127_1568341_3	584708.Apau_2420	4.739e-25	109.0	COG1959@1|root,COG1959@2|Bacteria,3TBDP@508458|Synergistetes	508458|Synergistetes	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158310_k127_1568341_1	1304885.AUEY01000064_gene2125	5.514e-47	186.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158310_k127_1575920_2	530564.Psta_4418	8.147e-48	181.0	COG0330@1|root,COG0330@2|Bacteria,2IYPR@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158310_k127_1575920_0	484770.UFO1_0374	2.302e-253	791.0	COG0033@1|root,COG0033@2|Bacteria,1UKP8@1239|Firmicutes,4H3T3@909932|Negativicutes	909932|Negativicutes	G	Phosphoglucomutase	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158310_k127_1575920_3	1122194.AUHU01000004_gene1549	1.113e-42	161.0	COG0545@1|root,COG0545@2|Bacteria,1RH0B@1224|Proteobacteria,1S6S9@1236|Gammaproteobacteria,467NY@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,FKBP_N
SRR25158310_k127_1575920_4	425104.Ssed_3434	9.645e-34	137.0	COG2716@1|root,COG2716@2|Bacteria,1NAIN@1224|Proteobacteria,1SEAU@1236|Gammaproteobacteria,2QC81@267890|Shewanellaceae	1236|Gammaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_4,ACT_6
SRR25158310_k127_1575920_1	1278307.KB906968_gene2060	2.296e-198	631.0	28IWB@1|root,2Z8UK@2|Bacteria,1P3IX@1224|Proteobacteria,1RRBU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3360
SRR25158310_k127_1582339_0	439235.Dalk_0137	2.534e-107	358.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MI9C@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158310_k127_1583428_2	290512.Paes_1341	2.386e-11	69.0	COG0004@1|root,COG0004@2|Bacteria,1FDC2@1090|Chlorobi	1090|Chlorobi	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158310_k127_1583428_1	247490.KSU1_D0341	1.508e-123	413.0	COG3653@1|root,COG3653@2|Bacteria,2IXWQ@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158310_k127_1583428_0	889378.Spiaf_0914	1.04e-138	449.0	28HY3@1|root,2Z83I@2|Bacteria	2|Bacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
SRR25158310_k127_1584563_0	1121406.JAEX01000001_gene490	4.13e-153	496.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2M9HZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158310_k127_1584563_1	1379281.AVAG01000010_gene1323	4.595e-35	139.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WJ8G@28221|Deltaproteobacteria,2M7Y8@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158310_k127_1588469_1	1123242.JH636436_gene323	4.146e-105	353.0	COG1363@1|root,COG1363@2|Bacteria,2IXMY@203682|Planctomycetes	203682|Planctomycetes	G	COG1363 Cellulase M and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158310_k127_1588469_0	1125863.JAFN01000001_gene769	9.152e-189	598.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158310_k127_1594296_1	1179155.CF67_04222	5.118e-44	173.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XTPN@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfC	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,RnfC_N,SLBB
SRR25158310_k127_1594296_2	545695.TREAZ_2619	5.898e-26	119.0	COG4658@1|root,COG4658@2|Bacteria,2J639@203691|Spirochaetes	203691|Spirochaetes	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
SRR25158310_k127_1594296_0	439235.Dalk_2437	1.546e-79	270.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,42NVQ@68525|delta/epsilon subdivisions,2WJFT@28221|Deltaproteobacteria,2MHX5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158310_k127_1602317_3	1090318.ATTI01000001_gene478	5.768e-10	67.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,2U93S@28211|Alphaproteobacteria,2K4MA@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein involved in polysaccharide	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158310_k127_1602317_0	1117108.PAALTS15_00725	5.302e-45	170.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,26TNS@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158310_k127_1602317_1	1410628.JNKS01000005_gene1220	1.229e-23	105.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,27P23@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158310_k127_1602317_2	1231185.BAMP01000022_gene2942	2.719e-12	67.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,43H01@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158310_k127_1604073_3	1131269.AQVV01000001_gene1297	6.907e-34	132.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	hit	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158310_k127_1604073_2	1396141.BATP01000039_gene1434	3.479e-63	222.0	COG1051@1|root,COG1051@2|Bacteria,46VWV@74201|Verrucomicrobia,2IVYW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158310_k127_1604073_0	1049564.TevJSym_ah00280	1.625e-142	458.0	COG3173@1|root,COG3173@2|Bacteria,1QXX9@1224|Proteobacteria,1T3J2@1236|Gammaproteobacteria,1J7RN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
SRR25158310_k127_1604073_1	1168034.FH5T_14945	5.352e-88	299.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes	976|Bacteroidetes	P	3'(2'),5'-bisphosphate nucleotidase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158310_k127_1604073_6	583355.Caka_3109	2.139e-08	68.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
SRR25158310_k127_1604073_5	479433.Caci_1443	1.263e-16	86.0	COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158310_k127_1604073_4	1142394.PSMK_03820	7.215e-20	98.0	2EVR7@1|root,33P56@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1607536_0	444158.MmarC6_0751	4.238e-114	375.0	COG0701@1|root,arCOG02712@2157|Archaea,2XT2F@28890|Euryarchaeota,23RAJ@183939|Methanococci	183939|Methanococci	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SRR25158310_k127_1607536_1	478741.JAFS01000001_gene1134	1.093e-73	258.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,37GF6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158310_k127_1607536_3	349161.Dred_0679	2.474e-12	77.0	COG1589@1|root,COG1589@2|Bacteria,1VEMW@1239|Firmicutes,24QKM@186801|Clostridia,26202@186807|Peptococcaceae	186801|Clostridia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158310_k127_1607536_2	497964.CfE428DRAFT_2928	1.126e-24	109.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158310_k127_1610347_3	411477.PARMER_01462	2.72e-05	48.0	2DR77@1|root,33AIC@2|Bacteria,4NZS2@976|Bacteroidetes,2G1QG@200643|Bacteroidia,2310T@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1610347_1	118161.KB235922_gene307	2.823e-175	562.0	COG1109@1|root,COG1109@2|Bacteria,1G20X@1117|Cyanobacteria,3VIYX@52604|Pleurocapsales	1117|Cyanobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158310_k127_1610347_0	671143.DAMO_2651	6.36e-232	735.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158310_k127_1610347_2	497964.CfE428DRAFT_5092	8.536e-30	127.0	COG2804@1|root,COG2804@2|Bacteria,46TUR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
SRR25158310_k127_1611798_0	1396141.BATP01000057_gene3037	2.983e-230	723.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,2ITND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,SIS
SRR25158310_k127_1611798_1	1396141.BATP01000035_gene4040	7.258e-30	125.0	COG0250@1|root,COG0250@2|Bacteria,46ZE1@74201|Verrucomicrobia,2IV04@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
SRR25158310_k127_1611798_2	382464.ABSI01000011_gene3200	1.292e-09	61.0	COG1510@1|root,COG1510@2|Bacteria,46VTX@74201|Verrucomicrobia,2IW6I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1613076_0	1191523.MROS_0294	3.245e-65	227.0	COG0825@1|root,COG0825@2|Bacteria	2|Bacteria	I	malonyl-CoA biosynthetic process	accA	GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN678.accA,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197	ACCA
SRR25158310_k127_1613076_1	247490.KSU1_C1551	2.291e-42	167.0	COG1376@1|root,COG1376@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
SRR25158310_k127_1613076_2	1538295.JY96_04915	6.92e-27	114.0	COG1032@1|root,COG1032@2|Bacteria,1PK5W@1224|Proteobacteria,2VJIN@28216|Betaproteobacteria,1KJM3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158310_k127_1615780_7	1121456.ATVA01000011_gene1569	8.197e-18	85.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2MB44@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158310_k127_1615780_3	1396418.BATQ01000175_gene2822	3.736e-67	239.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia,2IU44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158310_k127_1615780_0	497964.CfE428DRAFT_4159	3.61e-187	591.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158310_k127_1615780_2	379066.GAU_2073	9.367e-69	244.0	COG0008@1|root,COG0008@2|Bacteria,1ZURR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
SRR25158310_k127_1615780_5	1131553.JIBI01000021_gene259	2.09e-31	133.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,372EG@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158310_k127_1615780_6	358681.BBR47_03690	2.322e-21	102.0	COG1182@1|root,COG1182@2|Bacteria,1UGCK@1239|Firmicutes,4HAPQ@91061|Bacilli,26R96@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
SRR25158310_k127_1615780_4	313628.LNTAR_24159	2.243e-32	136.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
SRR25158310_k127_1615780_1	517417.Cpar_1754	8.379e-74	260.0	COG0763@1|root,COG0763@2|Bacteria,1FDN6@1090|Chlorobi	1090|Chlorobi	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158310_k127_1616268_2	518766.Rmar_1652	5.258e-05	49.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1FIZN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158310_k127_1616268_0	1313304.CALK_1993	6.886e-238	754.0	COG3968@1|root,COG3968@2|Bacteria	2|Bacteria	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158310_k127_1616268_1	472759.Nhal_3519	1.812e-75	262.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1WWER@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158310_k127_1623938_1	1329516.JPST01000035_gene3155	1.68e-66	238.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,27BCC@186824|Thermoactinomycetaceae	91061|Bacilli	S	KH domain	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158310_k127_1623938_2	1121403.AUCV01000013_gene3969	3.713e-41	157.0	COG1321@1|root,COG1321@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria,2MKI7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158310_k127_1623938_0	1265505.ATUG01000001_gene3145	6.663e-85	293.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria,2MMTV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
SRR25158310_k127_1628779_0	1123279.ATUS01000002_gene5	2.951e-257	799.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1J4T8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103	IlvC,IlvN
SRR25158310_k127_1628779_1	338963.Pcar_2519	2.196e-19	91.0	COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,42Q0Y@68525|delta/epsilon subdivisions,2WMJA@28221|Deltaproteobacteria,43UC6@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	LysR substrate binding domain	ilvY	-	-	ko:K02521	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158310_k127_163193_4	1230338.MOMA_02935	7.052e-08	65.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,3NJK6@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	SPOR,Secretin,Secretin_N
SRR25158310_k127_163193_0	573413.Spirs_3687	3.083e-273	850.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,2J6WY@203691|Spirochaetes	203691|Spirochaetes	C	Iron only hydrogenase large subunit, C-terminal domain	hymC	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3
SRR25158310_k127_163193_1	665571.STHERM_c13750	4.582e-261	817.0	COG1894@1|root,COG1894@2|Bacteria,2J5MT@203691|Spirochaetes	203691|Spirochaetes	C	NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRR25158310_k127_163193_2	1307761.L21SP2_0272	3.389e-65	226.0	COG1905@1|root,COG1905@2|Bacteria,2J7IH@203691|Spirochaetes	203691|Spirochaetes	C	Respiratory-chain NADH dehydrogenase 24 Kd subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158310_k127_163193_3	1123274.KB899426_gene2807	5.076e-26	109.0	COG2344@1|root,COG2344@2|Bacteria,2J89C@203691|Spirochaetes	203691|Spirochaetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158310_k127_163341_0	1168034.FH5T_09955	0.0	1574.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,2FNH9@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158310_k127_1660529_0	525897.Dbac_0042	2.183e-57	203.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2M87X@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158310_k127_1660529_2	382464.ABSI01000010_gene3810	7.084e-24	107.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1660529_4	344747.PM8797T_31795	1.109e-11	71.0	COG5126@1|root,COG5126@2|Bacteria,2J41T@203682|Planctomycetes	203682|Planctomycetes	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRR25158310_k127_1660529_3	1121918.ARWE01000001_gene2487	8.876e-21	100.0	2EJJY@1|root,33DAU@2|Bacteria,1NNY4@1224|Proteobacteria,430QY@68525|delta/epsilon subdivisions,2WVTF@28221|Deltaproteobacteria,43V88@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1660529_1	1207063.P24_06132	5.571e-53	188.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158310_k127_1662983_1	641491.DND132_0940	1.243e-157	510.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2M8FJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158310_k127_1662983_2	3067.XP_002956910.1	3.408e-100	333.0	COG0106@1|root,KOG3055@2759|Eukaryota,37JVT@33090|Viridiplantae,34GYY@3041|Chlorophyta	3041|Chlorophyta	E	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158310_k127_1662983_3	1121456.ATVA01000014_gene688	5.692e-46	171.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,42UA5@68525|delta/epsilon subdivisions,2WQWH@28221|Deltaproteobacteria,2M923@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1662983_0	1429916.X566_17240	1.142e-209	661.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,3JQTY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158310_k127_1662983_4	443143.GM18_1204	6.836e-14	74.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,43TG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
SRR25158310_k127_1670150_3	1384066.JAGT01000001_gene971	1.167e-07	61.0	2DMUC@1|root,32TQR@2|Bacteria,1V9Y3@1239|Firmicutes,24QZE@186801|Clostridia,3WQG3@541000|Ruminococcaceae	186801|Clostridia	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
SRR25158310_k127_1670150_0	1304885.AUEY01000030_gene2438	6.952e-108	359.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2WMFU@28221|Deltaproteobacteria,2MIVK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Phosphotransferase enzyme family	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158310_k127_1670150_1	478741.JAFS01000001_gene1900	9.852e-25	112.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia,37GPK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
SRR25158310_k127_1670150_2	497964.CfE428DRAFT_3130	4.696e-18	85.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
SRR25158310_k127_1674086_1	857293.CAAU_0332	5.135e-46	171.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,36DRX@31979|Clostridiaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
SRR25158310_k127_1674086_2	1123070.KB899251_gene717	7.378e-36	141.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158310_k127_1674086_0	478741.JAFS01000001_gene2110	2.552e-63	220.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,37FXU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158310_k127_1676939_1	290318.Cvib_0198	2.588e-102	338.0	COG1028@1|root,COG1028@2|Bacteria,1FDUA@1090|Chlorobi	1090|Chlorobi	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158310_k127_1676939_2	290512.Paes_0176	8.054e-73	255.0	COG0331@1|root,COG0331@2|Bacteria,1FDMY@1090|Chlorobi	1090|Chlorobi	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158310_k127_1676939_0	497964.CfE428DRAFT_3889	3.2e-117	385.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158310_k127_1676939_3	481448.Minf_1215	1.878e-69	241.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,37G4Q@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158310_k127_1683462_0	572546.Arcpr_1251	8.281e-45	178.0	COG0382@1|root,arCOG00477@2157|Archaea,2XW9S@28890|Euryarchaeota,24617@183980|Archaeoglobi	183980|Archaeoglobi	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158310_k127_1683462_1	404380.Gbem_0599	2.96e-34	134.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158310_k127_1686308_2	1313304.CALK_1730	2.264e-77	261.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158310_k127_1686308_0	313628.LNTAR_08211	8.849e-141	454.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gap3	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158310_k127_1686308_1	880073.Calab_2175	1.828e-115	391.0	COG0488@1|root,COG0488@2|Bacteria,2NNPH@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158310_k127_1686489_0	1168067.JAGP01000001_gene2036	4.187e-48	177.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,461YZ@72273|Thiotrichales	72273|Thiotrichales	S	Pfam:DUF258	-	-	-	-	-	-	-	-	-	-	-	-	RsgA_GTPase
SRR25158310_k127_1686489_1	1168034.FH5T_02985	1.149e-37	144.0	COG0824@1|root,COG0824@2|Bacteria,4NSJR@976|Bacteroidetes,2FS2E@200643|Bacteroidia	976|Bacteroidetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158310_k127_1702204_3	1403819.BATR01000184_gene6380	2.871e-47	172.0	COG0809@1|root,COG0809@2|Bacteria,46SDA@74201|Verrucomicrobia,2IU22@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158310_k127_1702204_1	1040987.AZUY01000011_gene5053	4.166e-76	261.0	COG4262@1|root,COG4262@2|Bacteria,1P1G3@1224|Proteobacteria,2TQSR@28211|Alphaproteobacteria,43J0P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Spermidine synthase	MA20_16695	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158310_k127_1702204_0	382464.ABSI01000006_gene860	5.713e-139	451.0	COG0513@1|root,COG0513@2|Bacteria,46UKA@74201|Verrucomicrobia,2IU1X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158310_k127_1702204_2	903818.KI912269_gene115	2.821e-62	222.0	COG0326@1|root,COG0326@2|Bacteria,3Y3QG@57723|Acidobacteria	57723|Acidobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
SRR25158310_k127_1710929_2	933262.AXAM01000014_gene241	1.015e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,1R099@1224|Proteobacteria,43CS6@68525|delta/epsilon subdivisions,2X7ZV@28221|Deltaproteobacteria,2MM36@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1710929_1	305900.GV64_12925	4.099e-28	131.0	COG0457@1|root,COG0457@2|Bacteria	305900.GV64_12925|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1710929_3	1167006.UWK_00742	9.705e-08	64.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
SRR25158310_k127_1710929_0	583355.Caka_0591	2.44e-58	215.0	COG2304@1|root,COG2304@2|Bacteria,46U0Q@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158310_k127_1710929_4	1168289.AJKI01000029_gene1441	2.615e-07	54.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,3XJ05@558415|Marinilabiliaceae	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SRR25158310_k127_1727990_0	243231.GSU2314	3.828e-99	338.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,43T08@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158310_k127_1727990_2	1207063.P24_05597	3.349e-51	184.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,2JSWF@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the UPF0260 family	-	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158310_k127_1727990_1	1232683.ADIMK_2291	3.254e-51	186.0	29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,1S4I9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1727990_3	696369.KI912183_gene1756	9.722e-48	177.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24MER@186801|Clostridia,266UI@186807|Peptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158310_k127_1730261_2	525898.Sdel_0877	2.278e-07	55.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2YQSD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158310_k127_1730261_0	194439.CT0698	9.593e-110	361.0	COG2022@1|root,COG2022@2|Bacteria,1FEGP@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158310_k127_1730261_1	527002.yaldo0001_30820	2.458e-30	123.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,1RNTV@1236|Gammaproteobacteria,41ERF@629|Yersinia	1236|Gammaproteobacteria	H	Thiazole biosynthesis protein thiH	thiH	GO:0003674,GO:0003824,GO:0005488,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0036355,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	iPC815.YPO3743,iSF_1195.SF4062,iSFxv_1172.SFxv_4429,iS_1188.S3673	BATS,Radical_SAM
SRR25158310_k127_1733889_0	1242864.D187_006303	9.55e-90	307.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158310_k127_1737491_6	177437.HRM2_36590	5.444e-10	63.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2MIKT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158310_k127_1737491_4	96561.Dole_2883	4.375e-18	91.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQHB@28221|Deltaproteobacteria,2MQ0A@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158310_k127_1737491_5	1121439.dsat_1405	4.112e-14	78.0	COG2259@1|root,COG2259@2|Bacteria,1RIFW@1224|Proteobacteria,42SRS@68525|delta/epsilon subdivisions,2WPBA@28221|Deltaproteobacteria,2MBXR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	MauE
SRR25158310_k127_1737491_2	926569.ANT_15570	2.152e-88	295.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158310_k127_1737491_1	665571.STHERM_c00510	1.233e-138	454.0	COG0766@1|root,COG0766@2|Bacteria,2J5JB@203691|Spirochaetes	203691|Spirochaetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158310_k127_1737491_3	1192034.CAP_0825	7.717e-66	231.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1737491_0	1192034.CAP_0825	1.356e-150	496.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1744060_3	403833.Pmob_1714	7.002e-15	79.0	COG0552@1|root,COG0552@2|Bacteria,2GBXG@200918|Thermotogae	200918|Thermotogae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158310_k127_1744060_0	1156937.MFUM_720039	1.299e-29	126.0	COG0781@1|root,COG0781@2|Bacteria,46VCF@74201|Verrucomicrobia,37GZF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158310_k127_1744060_1	1118054.CAGW01000090_gene3519	5.043e-28	119.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,26RCN@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRR25158310_k127_1744060_2	945713.IALB_2105	1.79e-15	76.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria	2|Bacteria	H	GTP cyclohydrolase II activity	ribBA	-	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158310_k127_1747432_1	207954.MED92_07731	8.018e-39	150.0	COG1765@1|root,COG1765@2|Bacteria,1QUE7@1224|Proteobacteria,1S84Z@1236|Gammaproteobacteria,1XKED@135619|Oceanospirillales	135619|Oceanospirillales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158310_k127_1747432_0	1123371.ATXH01000040_gene1169	2.266e-96	336.0	COG1022@1|root,COG1022@2|Bacteria,2GIQW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158310_k127_1748503_1	595460.RRSWK_02559	1.511e-115	392.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
SRR25158310_k127_1748503_2	525897.Dbac_2312	2.464e-13	83.0	COG3350@1|root,COG3350@2|Bacteria,1NE2T@1224|Proteobacteria,42VZQ@68525|delta/epsilon subdivisions,2WSDU@28221|Deltaproteobacteria,2MD4Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
SRR25158310_k127_1748503_0	237368.SCABRO_01551	9.785e-197	622.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SRR25158310_k127_1748963_1	338963.Pcar_2519	8.371e-74	252.0	COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,42Q0Y@68525|delta/epsilon subdivisions,2WMJA@28221|Deltaproteobacteria,43UC6@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	LysR substrate binding domain	ilvY	-	-	ko:K02521	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158310_k127_1748963_6	479436.Vpar_0349	1.275e-12	75.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR25158310_k127_1748963_5	1094980.Mpsy_0125	3.233e-13	81.0	arCOG04555@1|root,arCOG04555@2157|Archaea,2XUY2@28890|Euryarchaeota,2N9YH@224756|Methanomicrobia	224756|Methanomicrobia	S	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1748963_0	936589.HMPREF1521_1214	1.248e-106	355.0	COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4H2EK@909932|Negativicutes	909932|Negativicutes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
SRR25158310_k127_1748963_3	1123070.KB899268_gene2432	4.895e-50	188.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia,2IU5U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158310_k127_1748963_2	1249627.D779_3177	1.893e-68	241.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1WX5D@135613|Chromatiales	135613|Chromatiales	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158310_k127_1748963_4	261292.Nit79A3_0632	1.267e-18	85.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria,373HM@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1751714_1	1027273.GZ77_25170	5.623e-42	162.0	COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1XJ5W@135619|Oceanospirillales	135619|Oceanospirillales	Q	rRNA (Guanine-N1-)-methyltransferase	-	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158310_k127_1751714_0	497964.CfE428DRAFT_5917	1.647e-211	683.0	COG0553@1|root,COG0553@2|Bacteria,46S56@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase recycling family C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,RapA_C,SNF2_N
SRR25158310_k127_1752327_2	404589.Anae109_0139	1.222e-77	268.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158310_k127_1752327_5	1123250.KB908379_gene1041	5.309e-18	89.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes	1239|Firmicutes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158310_k127_1752327_1	1499689.CCNN01000007_gene1349	7.658e-142	468.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,36DXD@31979|Clostridiaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158310_k127_1752327_4	1160707.AJIK01000029_gene1643	1.532e-27	119.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,26F2P@186818|Planococcaceae	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158310_k127_1752327_0	497964.CfE428DRAFT_0415	5.356e-147	479.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158310_k127_1752327_3	1007103.AFHW01000039_gene2672	3.018e-40	162.0	COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli,274KT@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	lacC	-	2.7.1.144	ko:K00917	ko00052,ko01100,map00052,map01100	-	R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158310_k127_1761800_2	1235457.C404_10540	5.653e-34	137.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,1K7K5@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158310_k127_1761800_3	316067.Geob_3469	5.035e-32	127.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,42U6P@68525|delta/epsilon subdivisions,2WQ00@28221|Deltaproteobacteria,43V75@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	SMART HNH nuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_5
SRR25158310_k127_1761800_0	643473.KB235930_gene2548	5.124e-131	425.0	COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1HJTM@1161|Nostocales	1117|Cyanobacteria	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	ddh	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158310_k127_1761800_1	765869.BDW_14075	1.473e-60	213.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2MTQI@213481|Bdellovibrionales,2X7KM@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158310_k127_1762111_1	404380.Gbem_0425	8.199e-42	168.0	COG1730@1|root,COG1730@2|Bacteria,1QY94@1224|Proteobacteria,43CAY@68525|delta/epsilon subdivisions,2X7ME@28221|Deltaproteobacteria,43UWX@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR25158310_k127_1762111_0	313628.LNTAR_20323	3.323e-101	332.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
SRR25158310_k127_176248_0	1168034.FH5T_03200	4.698e-81	278.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,2FNGU@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158310_k127_176248_1	1232410.KI421428_gene1137	8.5e-80	273.0	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,42QPA@68525|delta/epsilon subdivisions,2WMPU@28221|Deltaproteobacteria,43TUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158310_k127_176248_2	1123256.KB907946_gene322	2.591e-18	91.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1X48D@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2,PLDc_N
SRR25158310_k127_1763400_3	743721.Psesu_0750	2.654e-37	145.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1SBBF@1236|Gammaproteobacteria,1XDAF@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158310_k127_1763400_0	1163617.SCD_n02929	8.78e-140	459.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158310_k127_1763400_1	643648.Slip_1424	8.147e-98	329.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42JKS@68298|Syntrophomonadaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
SRR25158310_k127_1763400_2	398512.JQKC01000008_gene868	1.505e-37	150.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3WG89@541000|Ruminococcaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15760	Porphobil_deam,Porphobil_deamC
SRR25158310_k127_1763400_4	293826.Amet_0058	1.018e-22	110.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,36EQI@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158310_k127_1766_1	909663.KI867150_gene459	2.722e-46	169.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MQ48@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158310_k127_1766_0	105559.Nwat_0143	3.095e-120	390.0	COG4976@1|root,COG4976@2|Bacteria,1RA4U@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158310_k127_1766_4	283699.D172_2392	0.0006817	46.0	COG0265@1|root,COG3344@1|root,COG0265@2|Bacteria,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,1S05V@1236|Gammaproteobacteria,2Q3PQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1,Trypsin_2
SRR25158310_k127_1766_2	283699.D172_2392	1.128e-12	71.0	COG0265@1|root,COG3344@1|root,COG0265@2|Bacteria,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,1S05V@1236|Gammaproteobacteria,2Q3PQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1,Trypsin_2
SRR25158310_k127_1766_3	246196.MSMEI_4943	2.63e-06	54.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,234JY@1762|Mycobacteriaceae	201174|Actinobacteria	O	serine protease	htrA	GO:0000785,GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005783,GO:0005789,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006915,GO:0006950,GO:0006974,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0008630,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009894,GO:0009898,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010506,GO:0010604,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030162,GO:0030163,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031329,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031984,GO:0032268,GO:0032270,GO:0032526,GO:0032991,GO:0033043,GO:0033554,GO:0033993,GO:0034097,GO:0034599,GO:0034605,GO:0035456,GO:0035458,GO:0035556,GO:0035631,GO:0042175,GO:0042221,GO:0042802,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043280,GO:0043281,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044429,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045786,GO:0045862,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051336,GO:0051345,GO:0051604,GO:0051716,GO:0051726,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0070206,GO:0070207,GO:0070848,GO:0070887,GO:0071229,GO:0071300,GO:0071310,GO:0071345,GO:0071363,GO:0071396,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0097190,GO:0097193,GO:0097194,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098802,GO:0098827,GO:0140096,GO:1900407,GO:1900408,GO:1901214,GO:1901215,GO:1901564,GO:1901565,GO:1901575,GO:1901700,GO:1901701,GO:1902175,GO:1902176,GO:1902494,GO:1902531,GO:1902532,GO:1902882,GO:1902883,GO:1903146,GO:1903201,GO:1903202,GO:1905286,GO:1905368,GO:1905369,GO:1905370,GO:2000116,GO:2001056,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001238,GO:2001239,GO:2001241,GO:2001242,GO:2001243,GO:2001267,GO:2001269	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158310_k127_1767340_0	1168034.FH5T_09955	6.035e-289	894.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,2FNH9@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158310_k127_177090_0	1317122.ATO12_15040	9.778e-128	422.0	COG1208@1|root,COG1409@1|root,COG5492@1|root,COG1208@2|Bacteria,COG1409@2|Bacteria,COG5492@2|Bacteria,4NHY5@976|Bacteroidetes,1HZI3@117743|Flavobacteriia,2YIDS@290174|Aquimarina	976|Bacteroidetes	N	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,fn3
SRR25158310_k127_177090_1	1265503.KB905169_gene232	2.046e-52	188.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPBC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158310_k127_1772844_1	349741.Amuc_0169	1.396e-53	195.0	COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia,2IU4F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158310_k127_1772844_2	1123376.AUIU01000014_gene577	2.689e-14	82.0	COG3170@1|root,COG3170@2|Bacteria,3J1DA@40117|Nitrospirae	40117|Nitrospirae	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158310_k127_1772844_0	313628.LNTAR_01145	3.423e-57	202.0	COG2131@1|root,COG2131@2|Bacteria	2|Bacteria	F	dCMP deaminase activity	dcdA	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158310_k127_1772844_3	1167006.UWK_00715	2.032e-05	48.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42NQG@68525|delta/epsilon subdivisions,2WJXC@28221|Deltaproteobacteria,2MJBJ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM DNA topoisomerase III, bacteria and conjugative plasmid	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DEAD,HRDC,Helicase_C,RecQ_Zn_bind,Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom
SRR25158310_k127_1775593_0	305900.GV64_09220	4.079e-56	200.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4743,NUDIX
SRR25158310_k127_1775593_1	717774.Marme_2979	3.826e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM2D@135619|Oceanospirillales	135619|Oceanospirillales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158310_k127_1779346_0	177439.DP0779	3.938e-208	655.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WJJM@28221|Deltaproteobacteria,2MI2J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
SRR25158310_k127_1779346_1	177439.DP0780	6.849e-37	146.0	COG3830@1|root,COG3830@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	gcvR	-	1.1.1.3	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_6
SRR25158310_k127_1780161_4	760568.Desku_0069	1.597e-12	68.0	COG1592@1|root,COG1592@2|Bacteria,1VB12@1239|Firmicutes,24JQ6@186801|Clostridia,262FT@186807|Peptococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1780161_2	7070.TC011681-PA	1.625e-64	230.0	COG0327@1|root,KOG4131@2759|Eukaryota,39U3J@33154|Opisthokonta,3BE81@33208|Metazoa,3CY48@33213|Bilateria,41XIF@6656|Arthropoda,3SGM6@50557|Insecta	33208|Metazoa	S	NIF3 (NGG1p interacting factor 3)	NIF3L1	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006355,GO:0007275,GO:0007399,GO:0008134,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0022008,GO:0030154,GO:0030182,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032501,GO:0032502,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158310_k127_1780161_0	1267533.KB906734_gene4161	2.317e-102	344.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158310_k127_1780161_3	573413.Spirs_2463	9.257e-29	120.0	2EET3@1|root,338KM@2|Bacteria,2JB85@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_1780161_1	794903.OPIT5_28345	1.947e-75	255.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,3K740@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158310_k127_1804711_0	1123057.P872_17925	4.275e-42	164.0	COG2755@1|root,COG2755@2|Bacteria,4NP89@976|Bacteroidetes,47Q5Q@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158310_k127_1811595_5	1396141.BATP01000057_gene3037	6.204e-25	105.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,2ITND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,SIS
SRR25158310_k127_1811595_3	657309.BXY_16270	2.747e-79	273.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,2FP00@200643|Bacteroidia,4AMGH@815|Bacteroidaceae	976|Bacteroidetes	P	3'(2'),5'-bisphosphate nucleotidase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158310_k127_1811595_1	1120999.JONM01000018_gene7	2.035e-136	440.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,2KQN4@206351|Neisseriales	206351|Neisseriales	H	Sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158310_k127_1811595_0	187272.Mlg_2345	6.783e-234	741.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1WWRV@135613|Chromatiales	135613|Chromatiales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158310_k127_1811595_2	96561.Dole_2525	6.529e-86	294.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WJC2@28221|Deltaproteobacteria,2MPU4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158310_k127_1811595_4	1122137.AQXF01000005_gene1385	3.851e-73	249.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158310_k127_18199_0	933262.AXAM01000039_gene1156	5.11e-56	206.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158310_k127_18199_1	526222.Desal_0393	2.441e-22	101.0	COG4968@1|root,COG4968@2|Bacteria,1QW3U@1224|Proteobacteria,43D0P@68525|delta/epsilon subdivisions,2X88I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158310_k127_18199_2	646529.Desaci_3437	0.0003633	50.0	COG4970@1|root,COG4970@2|Bacteria,1U4QW@1239|Firmicutes,25IDV@186801|Clostridia,266MB@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM general secretion pathway protein H	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	N_methyl
SRR25158310_k127_182172_0	1382306.JNIM01000001_gene274	2.202e-102	341.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158310_k127_182172_1	1121405.dsmv_1958	1.687e-36	150.0	COG0348@1|root,COG1148@1|root,COG3383@1|root,COG0348@2|Bacteria,COG1148@2|Bacteria,COG3383@2|Bacteria,1QUNB@1224|Proteobacteria,43BMZ@68525|delta/epsilon subdivisions,2X701@28221|Deltaproteobacteria,2MPPX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_5
SRR25158310_k127_1822821_0	1283283.ATXA01000018_gene4171	0.0007915	52.0	COG1749@1|root,COG3386@1|root,COG4932@1|root,COG1749@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales	201174|Actinobacteria	N	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,Mo-co_dimer,fn3
SRR25158310_k127_188240_0	349741.Amuc_1111	8.928e-162	515.0	COG0129@1|root,COG0129@2|Bacteria,46SBY@74201|Verrucomicrobia,2ITPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158310_k127_188240_1	118163.Ple7327_3370	4.629e-99	332.0	COG0502@1|root,COG0502@2|Bacteria,1G3B8@1117|Cyanobacteria,3VIF1@52604|Pleurocapsales	1117|Cyanobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.bioB	BATS,Radical_SAM
SRR25158310_k127_188240_2	1283299.AUKG01000001_gene2736	3.937e-92	316.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CR0Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158310_k127_190487_6	469616.FMAG_02300	2.656e-08	59.0	COG0360@1|root,COG0360@2|Bacteria,37APH@32066|Fusobacteria	32066|Fusobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158310_k127_190487_4	1231241.Mc24_03943	2.596e-47	176.0	COG0193@1|root,COG0193@2|Bacteria,2GD5F@200918|Thermotogae	200918|Thermotogae	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158310_k127_190487_5	1123371.ATXH01000007_gene553	4.989e-34	140.0	COG1825@1|root,COG1825@2|Bacteria,2GHKF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158310_k127_190487_2	1403819.BATR01000052_gene1575	2.258e-113	374.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,2ITT3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158310_k127_190487_0	314230.DSM3645_10642	1.925e-119	400.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158310_k127_190487_1	1121335.Clst_0833	4.727e-115	388.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3WHQA@541000|Ruminococcaceae	186801|Clostridia	H	Carbohydrate kinase, FGGY family protein	rhaB	-	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158310_k127_190487_3	1403819.BATR01000002_gene19	3.575e-102	340.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,2ITZR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
SRR25158310_k127_195429_1	794903.OPIT5_02580	2.211e-76	271.0	COG0251@1|root,COG0251@2|Bacteria,46V48@74201|Verrucomicrobia,3K8H7@414999|Opitutae	414999|Opitutae	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158310_k127_195429_0	889378.Spiaf_0914	1.962e-275	866.0	28HY3@1|root,2Z83I@2|Bacteria	2|Bacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
SRR25158310_k127_196345_2	880073.Calab_1614	1.146e-116	394.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158310_k127_196345_1	349741.Amuc_1288	2.055e-143	467.0	COG0826@1|root,COG0826@2|Bacteria,46TRX@74201|Verrucomicrobia,2IVH9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
SRR25158310_k127_196345_0	240016.ABIZ01000001_gene4539	3.131e-175	561.0	COG0621@1|root,COG0621@2|Bacteria,46S5U@74201|Verrucomicrobia,2ITS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Uncharacterized protein family UPF0004	-	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158310_k127_198410_0	1047013.AQSP01000142_gene150	1.159e-143	477.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158310_k127_198410_1	756272.Plabr_3170	1.432e-33	133.0	COG3119@1|root,COG3119@2|Bacteria,2J2AM@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
SRR25158310_k127_209578_1	497964.CfE428DRAFT_2937	7.932e-107	358.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158310_k127_209578_2	638302.HMPREF0908_1227	7.819e-77	273.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4H1XX@909932|Negativicutes	909932|Negativicutes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158310_k127_209578_0	555079.Toce_0947	1.108e-128	426.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,42ETI@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158310_k127_211540_2	313628.LNTAR_02522	5.406e-59	209.0	COG1116@1|root,COG1116@2|Bacteria	2|Bacteria	P	anion transmembrane transporter activity	nrtD	-	3.6.3.36	ko:K02049,ko:K10831,ko:K15578,ko:K15579	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00188,M00435,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
SRR25158310_k127_211540_1	313628.LNTAR_02517	6.144e-106	353.0	COG1116@1|root,COG1116@2|Bacteria	2|Bacteria	P	anion transmembrane transporter activity	-	-	-	ko:K02049,ko:K15578	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.17	-	-	ABC_tran
SRR25158310_k127_211540_0	313628.LNTAR_02512	3.77e-118	383.0	COG0600@1|root,COG0600@2|Bacteria	2|Bacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	nrtB	-	-	ko:K15577	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16.1,3.A.1.16.2	-	-	BPD_transp_1
SRR25158310_k127_221068_0	497964.CfE428DRAFT_0088	9.416e-46	178.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158310_k127_221068_1	762968.HMPREF9441_00402	8.216e-13	73.0	COG0438@1|root,COG0438@2|Bacteria,4NGSA@976|Bacteroidetes,2FPXN@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_222903_0	398767.Glov_2829	9.929e-269	841.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158310_k127_222903_4	481448.Minf_2177	7.049e-36	138.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158310_k127_222903_1	382464.ABSI01000006_gene754	4.927e-260	810.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158310_k127_222903_5	497964.CfE428DRAFT_6679	0.0002586	47.0	COG1758@1|root,COG1758@2|Bacteria,46T94@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158310_k127_222903_3	883110.HMPREF9260_00948	2.23e-44	166.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,27E0Q@186827|Aerococcaceae	91061|Bacilli	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158310_k127_222903_2	946483.Cenrod_1917	1.221e-102	344.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1NR3M@1224|Proteobacteria,2VJSV@28216|Betaproteobacteria,4AAZZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C,Rieske
SRR25158310_k127_223382_5	518766.Rmar_1666	1.905e-40	155.0	COG1232@1|root,COG1232@2|Bacteria,4NH1E@976|Bacteroidetes,1FIR6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158310_k127_223382_1	391587.KAOT1_18008	1.425e-96	327.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1HXUV@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158310_k127_223382_2	1380763.BG53_09475	2.066e-75	269.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,26RX4@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the folylpolyglutamate synthase family	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158310_k127_223382_0	497964.CfE428DRAFT_2029	6.058e-97	324.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158310_k127_223382_4	497964.CfE428DRAFT_2030	5.498e-46	175.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia	74201|Verrucomicrobia	S	competence protein	comFC	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158310_k127_223382_6	1408823.AXUS01000003_gene589	4.403e-10	70.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1V343@1239|Firmicutes,24YXC@186801|Clostridia,25RH0@186804|Peptostreptococcaceae	186801|Clostridia	MT	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
SRR25158310_k127_223382_3	595494.Tola_2185	3.35e-58	211.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1Y3X3@135624|Aeromonadales	135624|Aeromonadales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158310_k127_233676_2	497964.CfE428DRAFT_3286	2.696e-38	159.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_233676_1	1501230.ET33_16960	6.884e-82	283.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,26RTF@186822|Paenibacillaceae	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
SRR25158310_k127_233676_0	1396418.BATQ01000008_gene1456	7.325e-112	368.0	COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia,2ITH9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158310_k127_233676_3	658172.CKC_03805	1.211e-09	60.0	COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,2U0KU@28211|Alphaproteobacteria,4BEVC@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158310_k127_23447_0	760192.Halhy_5289	1.115e-89	302.0	COG3552@1|root,COG3552@2|Bacteria,4NK40@976|Bacteroidetes,1IWRV@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158310_k127_23447_1	700598.Niako_5154	2.2e-78	272.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,4NP35@976|Bacteroidetes,1IVW7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158310_k127_23447_2	1121904.ARBP01000019_gene2813	1.923e-55	199.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158310_k127_235842_4	240016.ABIZ01000001_gene2754	3.429e-14	78.0	COG1560@1|root,COG1560@2|Bacteria,46VIS@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
SRR25158310_k127_235842_0	1167006.UWK_00068	3.246e-113	374.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,1RDA1@1224|Proteobacteria,43BUM@68525|delta/epsilon subdivisions,2WMFR@28221|Deltaproteobacteria,2MIPP@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C,Pro_isomerase
SRR25158310_k127_235842_1	1121324.CLIT_11c01180	2.55e-83	293.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158310_k127_235842_3	530564.Psta_1748	5.892e-16	87.0	COG1381@1|root,COG1381@2|Bacteria,2IZU9@203682|Planctomycetes	203682|Planctomycetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158310_k127_235842_2	194439.CT0919	2.809e-47	180.0	COG1215@1|root,COG1215@2|Bacteria,1FFPY@1090|Chlorobi	1090|Chlorobi	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158310_k127_237165_0	313628.LNTAR_03604	1.721e-35	149.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158310_k127_250941_1	497964.CfE428DRAFT_3562	1.127e-43	166.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158310_k127_250941_0	497964.CfE428DRAFT_0602	1.946e-163	532.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	2|Bacteria	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158310_k127_252655_1	313628.LNTAR_18865	2.548e-106	352.0	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
SRR25158310_k127_252655_0	1403819.BATR01000133_gene4729	6.169e-138	446.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158310_k127_252655_3	497964.CfE428DRAFT_3929	1.431e-27	123.0	COG1792@1|root,COG1792@2|Bacteria,46T2J@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158310_k127_252655_2	497964.CfE428DRAFT_3931	5.609e-78	288.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
SRR25158310_k127_256398_0	388413.ALPR1_19473	2.263e-211	664.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158310_k127_256398_3	1123279.ATUS01000001_gene2111	5.679e-68	241.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1J64Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Phosphomethylpyrimidine kinase	thiE	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
SRR25158310_k127_256398_4	744872.Spica_1647	1.294e-54	192.0	COG0347@1|root,COG0347@2|Bacteria,2J7M4@203691|Spirochaetes	203691|Spirochaetes	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
SRR25158310_k127_256398_1	1191523.MROS_2397	2.685e-161	518.0	COG0004@1|root,COG0004@2|Bacteria	2|Bacteria	P	ammonium transporteR	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iJN678.amt2	Ammonium_transp
SRR25158310_k127_256398_2	1307761.L21SP2_2105	1.736e-132	442.0	COG3605@1|root,COG3605@2|Bacteria,2JBCF@203691|Spirochaetes	203691|Spirochaetes	T	GAF domain	-	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158310_k127_264006_2	1121468.AUBR01000004_gene168	3.038e-14	74.0	COG1592@1|root,COG1592@2|Bacteria,1VB12@1239|Firmicutes,24JQ6@186801|Clostridia,42H0K@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_264006_1	1121448.DGI_3061	1.184e-50	183.0	COG0636@1|root,COG0636@2|Bacteria,1N04D@1224|Proteobacteria,42TS9@68525|delta/epsilon subdivisions,2WQ2Y@28221|Deltaproteobacteria,2MBJE@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
SRR25158310_k127_264006_0	1307759.JOMJ01000003_gene1587	9.771e-102	344.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42QGM@68525|delta/epsilon subdivisions,2WR5N@28221|Deltaproteobacteria,2MA35@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
SRR25158310_k127_267278_1	1265505.ATUG01000001_gene4350	3.906e-11	76.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,42Q0T@68525|delta/epsilon subdivisions,2WM1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
SRR25158310_k127_267278_0	1125863.JAFN01000001_gene910	5.761e-97	323.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
SRR25158310_k127_27460_0	1284352.AOIG01000003_gene1027	1.083e-128	420.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,26SI9@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158310_k127_277598_0	313628.LNTAR_25000	1.421e-124	417.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158310_k127_293110_0	596319.STAWA0001_0787	2.152e-88	306.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,4GXUP@90964|Staphylococcaceae	91061|Bacilli	J	Uncharacterized protein family UPF0004	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158310_k127_293110_1	429009.Adeg_0961	1.265e-40	159.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,42FUI@68295|Thermoanaerobacterales	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158310_k127_293110_2	573064.Mefer_1171	2.793e-19	90.0	COG2231@1|root,arCOG00461@2157|Archaea,2Y86S@28890|Euryarchaeota,23R2Z@183939|Methanococci	183939|Methanococci	L	PFAM HhH-GPD family protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
SRR25158310_k127_302900_1	1396141.BATP01000041_gene2222	3.406e-70	254.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,2ITNT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158310_k127_302900_2	2340.JV46_15830	5.469e-58	215.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1J4FG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
SRR25158310_k127_302900_4	1123274.KB899407_gene258	2.054e-20	96.0	29IC7@1|root,3059E@2|Bacteria,2JAQH@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_302900_0	335543.Sfum_0076	1.165e-74	260.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,2MR34@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
SRR25158310_k127_302900_3	313628.LNTAR_23689	1.648e-37	144.0	COG0231@1|root,COG0231@2|Bacteria	2|Bacteria	J	translation elongation factor activity	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158310_k127_31152_0	118168.MC7420_8226	0.0	1105.0	COG1882@1|root,COG1882@2|Bacteria,1FZXQ@1117|Cyanobacteria,1HA19@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate formate lyase	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
SRR25158310_k127_31585_0	246194.CHY_0713	4.834e-48	177.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,42EWF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158310_k127_31585_1	570967.JMLV01000012_gene3172	3.988e-09	68.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SRR25158310_k127_325378_0	177437.HRM2_09160	4.379e-169	544.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,2MHQP@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158310_k127_325378_2	1123070.KB899250_gene482	8.122e-65	233.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158310_k127_325378_1	794903.OPIT5_07620	2.746e-70	247.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,3K75I@414999|Opitutae	414999|Opitutae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
SRR25158310_k127_325378_3	497964.CfE428DRAFT_1791	1.553e-06	52.0	COG0858@1|root,COG0858@2|Bacteria,46TBI@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158310_k127_331414_2	693977.Deipr_1105	1.706e-23	101.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158310_k127_331414_3	1236542.BALM01000004_gene2471	3.389e-10	69.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,2Q99P@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM peptidase M22 glycoprotease	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158310_k127_331414_0	635013.TherJR_0728	3.35e-36	141.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158310_k127_331414_1	595460.RRSWK_04736	1.065e-27	128.0	28HU5@1|root,2Z80X@2|Bacteria	2|Bacteria	S	TIGRFAM TIGR03790 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_332737_3	485918.Cpin_6484	2.109e-50	183.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,1ITWU@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158310_k127_332737_2	247490.KSU1_C1542	3.029e-61	225.0	COG2081@1|root,COG2081@2|Bacteria,2IWW4@203682|Planctomycetes	203682|Planctomycetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158310_k127_332737_1	237368.SCABRO_02572	4.018e-182	586.0	COG0119@1|root,COG0119@2|Bacteria,2IXBC@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158310_k127_332737_0	498761.HM1_2749	1.294e-303	952.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158310_k127_339065_4	1167006.UWK_01333	6.612e-05	46.0	COG0834@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHXZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_3
SRR25158310_k127_339065_0	1242864.D187_007813	4.387e-126	419.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158310_k127_339065_2	1329516.JPST01000015_gene695	7.991e-29	118.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,27C7E@186824|Thermoactinomycetaceae	91061|Bacilli	J	Translation initiation factor 1A / IF-1	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158310_k127_339065_1	756272.Plabr_3346	5.603e-112	374.0	COG0733@1|root,COG0733@2|Bacteria,2J29X@203682|Planctomycetes	203682|Planctomycetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
SRR25158310_k127_347686_1	350688.Clos_2291	8.403e-56	199.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,36UI7@31979|Clostridiaceae	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
SRR25158310_k127_347686_0	700015.Corgl_0171	2.031e-56	213.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CUYP@84998|Coriobacteriia	84998|Coriobacteriia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158310_k127_353816_8	1232437.KL661988_gene204	1.833e-06	53.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1QW0T@1224|Proteobacteria,43BQQ@68525|delta/epsilon subdivisions,2X71S@28221|Deltaproteobacteria,2MPIV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
SRR25158310_k127_353816_5	439235.Dalk_2977	1.836e-52	198.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MIED@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SRR25158310_k127_353816_3	1396141.BATP01000026_gene1005	2.253e-97	321.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia,2IU46@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158310_k127_353816_1	452637.Oter_3368	4.356e-158	513.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158310_k127_353816_0	1249627.D779_0326	2.438e-168	542.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,1RNFZ@1236|Gammaproteobacteria,1WVYP@135613|Chromatiales	135613|Chromatiales	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158310_k127_353816_6	397291.C804_00124	3.036e-36	141.0	COG0139@1|root,COG0139@2|Bacteria	2|Bacteria	E	phosphoribosyl-AMP cyclohydrolase activity	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158310_k127_353816_2	62928.azo3344	4.811e-113	370.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,2KV5N@206389|Rhodocyclales	206389|Rhodocyclales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158310_k127_353816_4	1157490.EL26_23840	5.034e-92	316.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,279D9@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158310_k127_353816_7	349161.Dred_0983	4.244e-35	137.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,24M00@186801|Clostridia,266UW@186807|Peptococcaceae	186801|Clostridia	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158310_k127_365083_0	1150600.ADIARSV_2634	4.046e-101	350.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQT8@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 C terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158310_k127_365083_2	497964.CfE428DRAFT_0327	1.834e-06	61.0	COG1361@1|root,COG1404@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4733@2|Bacteria,46UDB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5122
SRR25158310_k127_365083_3	1237149.C900_05552	2.905e-05	57.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
SRR25158310_k127_365083_1	1123070.KB899262_gene1677	3.495e-07	64.0	COG0412@1|root,COG1404@1|root,COG2755@1|root,COG3317@1|root,COG0412@2|Bacteria,COG1404@2|Bacteria,COG2755@2|Bacteria,COG3317@2|Bacteria,46WFV@74201|Verrucomicrobia,2IUW0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
SRR25158310_k127_369481_0	56780.SYN_02257	6.58e-278	868.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,43AEI@68525|delta/epsilon subdivisions,2X5UC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Alpha amylase	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158310_k127_369481_1	439235.Dalk_0888	4.006e-172	548.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
SRR25158310_k127_378806_2	933262.AXAM01000074_gene3373	2.02e-70	248.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2MMS5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158310_k127_378806_0	1499967.BAYZ01000061_gene5928	2.265e-259	811.0	COG2759@1|root,COG2759@2|Bacteria,2NP2R@2323|unclassified Bacteria	2|Bacteria	F	Formate--tetrahydrofolate ligase	fhs	GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
SRR25158310_k127_378806_1	1286106.MPL1_05724	3.408e-85	291.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Formate nitrite	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
SRR25158310_k127_378806_3	649747.HMPREF0083_05488	4.003e-38	151.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,26WZ2@186822|Paenibacillaceae	91061|Bacilli	L	AdP-ribose pyrophosphatase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
SRR25158310_k127_379309_0	521674.Plim_2772	5.62e-69	244.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
SRR25158310_k127_379309_1	102125.Xen7305DRAFT_00030280	6.404e-09	69.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GDU9@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VCBS
SRR25158310_k127_38355_0	443143.GM18_3055	3.585e-63	224.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42W4B@68525|delta/epsilon subdivisions,2WP0P@28221|Deltaproteobacteria,43UMI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158310_k127_38355_1	1198232.CYCME_0088	3.187e-21	104.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,46030@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
SRR25158310_k127_386756_0	1278307.KB906986_gene4278	1.206e-41	160.0	COG5026@1|root,COG5026@2|Bacteria,1NW3J@1224|Proteobacteria,1SSJW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Hexokinase	-	-	-	-	-	-	-	-	-	-	-	-	Hexokinase_1,Hexokinase_2
SRR25158310_k127_386756_1	1185876.BN8_03477	2.586e-10	71.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,47SIE@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158310_k127_388943_2	583355.Caka_2021	1.434e-52	191.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,3K7ER@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158310_k127_388943_0	485915.Dret_0903	8.046e-144	460.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,42NT2@68525|delta/epsilon subdivisions,2WJM5@28221|Deltaproteobacteria,2M7VT@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158310_k127_388943_4	1480694.DC28_14035	1.238e-33	138.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	nnrR	-	-	ko:K01420,ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158310_k127_388943_3	335543.Sfum_2934	3.683e-34	135.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria,2MQJ4@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158310_k127_388943_1	926561.KB900617_gene1957	1.342e-82	282.0	COG1149@1|root,COG1149@2|Bacteria,1VUEG@1239|Firmicutes,2503A@186801|Clostridia,3WBJP@53433|Halanaerobiales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_6
SRR25158310_k127_393465_0	886293.Sinac_3058	4.634e-30	121.0	COG1249@1|root,COG1249@2|Bacteria,2IY39@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158310_k127_393465_1	247490.KSU1_B0531	4.624e-26	114.0	COG1262@1|root,COG1262@2|Bacteria,2J3GG@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158310_k127_402222_3	269799.Gmet_2357	3.262e-33	142.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,43UEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158310_k127_402222_0	221109.22779149	3.269e-98	337.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,23JJJ@182709|Oceanobacillus	91061|Bacilli	L	DnaB-like helicase N terminal domain	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158310_k127_402222_1	880073.Calab_2408	1.071e-38	149.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158310_k127_402222_4	1308866.J416_13359	1.34e-13	72.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,47147@74385|Gracilibacillus	91061|Bacilli	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158310_k127_402222_2	478741.JAFS01000001_gene1846	4.657e-37	143.0	COG0629@1|root,COG0629@2|Bacteria,46VWS@74201|Verrucomicrobia,37GQJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158310_k127_404887_4	240016.ABIZ01000001_gene1279	1.57e-10	67.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia,2IUS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158310_k127_404887_0	1121918.ARWE01000001_gene2901	9.381e-135	443.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43U7Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158310_k127_404887_1	574087.Acear_2191	1.939e-70	246.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,24EGS@186801|Clostridia,3WAIK@53433|Halanaerobiales	186801|Clostridia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158310_k127_404887_2	635013.TherJR_2822	1.165e-46	172.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,261X9@186807|Peptococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158310_k127_404887_3	240016.ABIZ01000001_gene3184	2.921e-20	94.0	COG0727@1|root,COG0727@2|Bacteria,46W4U@74201|Verrucomicrobia,2IUJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158310_k127_408239_1	1296416.JACB01000010_gene1582	1.733e-116	391.0	COG1208@1|root,COG1409@1|root,COG5492@1|root,COG1208@2|Bacteria,COG1409@2|Bacteria,COG5492@2|Bacteria,4NHY5@976|Bacteroidetes,1HZI3@117743|Flavobacteriia,2YIDS@290174|Aquimarina	976|Bacteroidetes	N	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,fn3
SRR25158310_k127_408239_0	1121101.HMPREF1532_01617	1.013e-172	570.0	COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,2FMTQ@200643|Bacteroidia,4AM6D@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158310_k127_408585_6	1396418.BATQ01000135_gene3643	4.483e-18	87.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,2IUKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158310_k127_408585_1	643648.Slip_0136	5.457e-89	301.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42JSG@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158310_k127_408585_0	857293.CAAU_0953	7.706e-93	312.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,36E8S@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158310_k127_408585_5	1033802.SSPSH_000138	4.188e-44	165.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158310_k127_408585_4	696369.KI912183_gene2605	1.04e-46	177.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,24GE9@186801|Clostridia	186801|Clostridia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158310_k127_408585_3	1120985.AUMI01000011_gene248	1.425e-47	172.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4H4NT@909932|Negativicutes	909932|Negativicutes	P	alkylphosphonate utilization operon protein PhnA	-	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
SRR25158310_k127_408585_2	1519464.HY22_11145	3.834e-53	194.0	COG0496@1|root,COG0496@2|Bacteria,1FDEQ@1090|Chlorobi	1090|Chlorobi	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158310_k127_413773_2	330214.NIDE3875	9.795e-34	136.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,3J0TG@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SRR25158310_k127_413773_0	247490.KSU1_D0949	3.019e-145	471.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158310_k127_413773_1	330214.NIDE3873	1.137e-52	190.0	COG1013@1|root,COG1013@2|Bacteria,3J0KG@40117|Nitrospirae	40117|Nitrospirae	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158310_k127_420628_3	545694.TREPR_0645	0.0002445	46.0	COG0136@1|root,335ZB@2|Bacteria,2J86M@203691|Spirochaetes	203691|Spirochaetes	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
SRR25158310_k127_420628_1	314292.VAS14_20826	1.098e-86	294.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XSUQ@135623|Vibrionales	135623|Vibrionales	H	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	ygdL	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
SRR25158310_k127_420628_2	1206777.B195_19356	7.154e-11	69.0	COG0782@1|root,COG0782@2|Bacteria,1MZNI@1224|Proteobacteria,1SED1@1236|Gammaproteobacteria,1Z55E@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	Elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
SRR25158310_k127_420628_0	1122201.AUAZ01000003_gene1971	1.819e-92	306.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,466AV@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
SRR25158310_k127_420897_0	1313304.CALK_1730	7.528e-73	253.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158310_k127_420897_4	667014.Thein_1637	2.097e-12	72.0	arCOG05277@1|root,336C4@2|Bacteria,2GIJP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_420897_1	583355.Caka_2360	1.961e-68	238.0	COG0131@1|root,COG0131@2|Bacteria,46UDT@74201|Verrucomicrobia,3K7V8@414999|Opitutae	414999|Opitutae	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158310_k127_420897_2	1396141.BATP01000062_gene4452	1.69e-58	209.0	COG0118@1|root,COG0118@2|Bacteria,46V4G@74201|Verrucomicrobia,2IUAC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158310_k127_420897_3	439235.Dalk_1867	1.107e-57	212.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG4936@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158310_k127_425420_2	1163408.UU9_06274	1.722e-83	285.0	COG0314@1|root,COG0476@1|root,COG0314@2|Bacteria,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1X3YQ@135614|Xanthomonadales	135614|Xanthomonadales	H	ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase	moeB	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
SRR25158310_k127_425420_3	1123227.KB899336_gene388	1.483e-17	85.0	COG1977@1|root,COG1977@2|Bacteria,1R1EN@1224|Proteobacteria,2TZ0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
SRR25158310_k127_425420_1	1123073.KB899244_gene303	2.219e-115	381.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1X46A@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158310_k127_425420_0	448385.sce8491	4.191e-219	691.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2X7DH@28221|Deltaproteobacteria,2YWG8@29|Myxococcales	68525|delta/epsilon subdivisions	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158310_k127_429424_0	313628.LNTAR_03909	2.847e-148	490.0	COG0531@1|root,COG1762@1|root,COG0531@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806,ko:K16263	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.3.13,4.A.2.1	-	-	AA_permease,AA_permease_2,Na_H_Exchanger,PTS_EIIA_2,TrkA_C
SRR25158310_k127_429424_6	714943.Mucpa_1298	1.303e-05	50.0	COG1961@1|root,COG1961@2|Bacteria,4NHW0@976|Bacteroidetes,1IR5S@117747|Sphingobacteriia	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
SRR25158310_k127_429424_1	1123368.AUIS01000004_gene110	4.079e-79	280.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,1RZ3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_429424_4	1439940.BAY1663_04961	2.319e-53	192.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
SRR25158310_k127_429424_5	1117644.MCANPG14_02411	3.076e-29	123.0	COG0742@1|root,COG0742@2|Bacteria,3WTBQ@544448|Tenericutes	544448|Tenericutes	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158310_k127_429424_2	243231.GSU2189	3.268e-76	269.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,43SHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
SRR25158310_k127_429424_3	1449126.JQKL01000018_gene3257	3.017e-57	208.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,268GC@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158310_k127_433227_1	111780.Sta7437_1478	3.285e-114	380.0	COG2227@1|root,COG2227@2|Bacteria,1G1XD@1117|Cyanobacteria,3VI2X@52604|Pleurocapsales	1117|Cyanobacteria	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_14,Methyltransf_23
SRR25158310_k127_433227_0	880070.Cycma_1330	1.296e-135	439.0	COG0451@1|root,COG0451@2|Bacteria,4NI4N@976|Bacteroidetes,47RQ3@768503|Cytophagia	976|Bacteroidetes	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158310_k127_433227_2	314345.SPV1_00517	3.212e-55	199.0	COG1216@1|root,COG1216@2|Bacteria,1RB30@1224|Proteobacteria	1224|Proteobacteria	U	Pfam Glycosyl transferase family 2	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
SRR25158310_k127_444116_2	909663.KI867150_gene1086	5.864e-41	154.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158310_k127_444116_3	290397.Adeh_0645	1.173e-40	170.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158310_k127_444116_0	2325.TKV_c11760	1.93e-137	456.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158310_k127_444116_1	706587.Desti_3122	1.42e-63	234.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MQAH@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158310_k127_444116_5	748658.KB907319_gene723	3.31e-06	54.0	COG4969@1|root,COG4969@2|Bacteria,1N4MN@1224|Proteobacteria,1S7ZB@1236|Gammaproteobacteria,1X294@135613|Chromatiales	135613|Chromatiales	NU	Pilin (bacterial filament)	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
SRR25158310_k127_444116_4	1232410.KI421416_gene2559	9.964e-11	73.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,43RYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158310_k127_446328_0	1265503.KB905169_gene276	6.773e-105	367.0	COG1874@1|root,COG3291@1|root,COG1874@2|Bacteria,COG3291@2|Bacteria,1R702@1224|Proteobacteria,1RUC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158310_k127_446328_2	1408473.JHXO01000004_gene191	8.989e-50	181.0	COG2606@1|root,COG2606@2|Bacteria,4P3TW@976|Bacteroidetes,2FXVH@200643|Bacteroidia	976|Bacteroidetes	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158310_k127_446328_1	335543.Sfum_0711	5.831e-66	229.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2MQFU@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	kamA2	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
SRR25158310_k127_448272_1	247490.KSU1_A0087	6.588e-39	153.0	COG0297@1|root,COG0297@2|Bacteria,2IX7T@203682|Planctomycetes	203682|Planctomycetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158310_k127_448272_0	203119.Cthe_0146	2.567e-128	436.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158310_k127_452802_3	502025.Hoch_6045	3.128e-34	142.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1Q53R@1224|Proteobacteria,430W1@68525|delta/epsilon subdivisions,2WVP7@28221|Deltaproteobacteria,2YWDG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SRR25158310_k127_452802_1	314345.SPV1_13102	1.054e-121	399.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria	1224|Proteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760	Coprogen_oxidas
SRR25158310_k127_452802_0	880073.Calab_0516	9.375e-134	451.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,PDZ_2,Peptidase_S41
SRR25158310_k127_452802_2	485913.Krac_5146	4.397e-59	212.0	COG0166@1|root,COG0166@2|Bacteria,2G5ZM@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158310_k127_45787_3	1453501.JELR01000002_gene629	9.026e-06	49.0	COG4641@1|root,COG4641@2|Bacteria,1RD4C@1224|Proteobacteria,1RYDA@1236|Gammaproteobacteria,46A53@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
SRR25158310_k127_45787_1	1123279.ATUS01000001_gene1738	2.379e-97	326.0	COG0463@1|root,COG0463@2|Bacteria,1RBHD@1224|Proteobacteria,1S3K4@1236|Gammaproteobacteria,1J96N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158310_k127_45787_2	713586.KB900536_gene1648	1.301e-89	306.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria,1WW1R@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_45787_0	1165841.SULAR_06548	5.089e-121	399.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,42M2P@68525|delta/epsilon subdivisions,2YNS6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_45787_4	1112217.PPL19_18090	0.00085	45.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980	ABC_membrane,ABC_tran
SRR25158310_k127_460590_0	1379281.AVAG01000032_gene115	1.243e-152	487.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158310_k127_460590_2	309801.trd_0334	1.267e-47	186.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi,27Y1X@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158310_k127_460590_1	583355.Caka_0770	1.468e-59	210.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
SRR25158310_k127_469445_2	1242864.D187_001758	6.929e-49	185.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158310_k127_469445_4	313628.LNTAR_15972	1.803e-08	58.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158310_k127_469445_0	443143.GM18_1367	4.517e-61	222.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158310_k127_469445_1	926692.AZYG01000018_gene290	6.731e-56	205.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WAPR@53433|Halanaerobiales	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158310_k127_469445_3	1469245.JFBG01000011_gene816	2.602e-28	119.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WX0T@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158310_k127_474019_0	309799.DICTH_1386	2.589e-82	284.0	COG0301@1|root,COG1293@1|root,COG0301@2|Bacteria,COG1293@2|Bacteria	2|Bacteria	K	actin binding	FbpA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	DUF814,FbpA,ThiI
SRR25158310_k127_474019_2	1210884.HG799462_gene8087	1.273e-32	136.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158310_k127_474019_1	706587.Desti_2609	1.785e-51	190.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2MRA3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158310_k127_482673_0	497964.CfE428DRAFT_6711	4.08e-93	317.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
SRR25158310_k127_482673_1	694431.DESACE_07230	6.837e-51	196.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2M78C@213113|Desulfurellales	28221|Deltaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158310_k127_485599_0	497964.CfE428DRAFT_6114	2.954e-111	385.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
SRR25158310_k127_486184_0	986075.CathTA2_0939	3.715e-124	415.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158310_k127_487833_1	1122169.AREN01000045_gene2118	1.316e-28	117.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,1T6YV@1236|Gammaproteobacteria,1JEIY@118969|Legionellales	118969|Legionellales	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
SRR25158310_k127_487833_3	1268239.PALB_2930	6.861e-08	64.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,2PZTT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
SRR25158310_k127_487833_2	1304275.C41B8_09801	6.929e-28	116.0	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,1SEQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CbiX	cbiX	-	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
SRR25158310_k127_487833_0	944479.JQLX01000004_gene197	1.532e-274	860.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2M6MN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158310_k127_491507_1	344747.PM8797T_23971	5.129e-98	334.0	COG0389@1|root,COG0389@2|Bacteria,2IZ2I@203682|Planctomycetes	203682|Planctomycetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158310_k127_491507_0	384765.SIAM614_17489	5.692e-207	655.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158310_k127_492473_0	583355.Caka_2912	1.278e-83	279.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia,3K7Z3@414999|Opitutae	414999|Opitutae	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SRR25158310_k127_492473_1	497964.CfE428DRAFT_1521	1.243e-58	209.0	COG0461@1|root,COG0461@2|Bacteria,46SZV@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158310_k127_492473_2	1123070.KB899259_gene1966	1.231e-22	107.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,2IUE8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158310_k127_492565_1	205922.Pfl01_3192	3.245e-24	108.0	2DPMZ@1|root,332QC@2|Bacteria,1NM9H@1224|Proteobacteria,1SQJU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_492565_0	1308866.J416_12082	8.297e-90	298.0	COG1225@1|root,COG1225@2|Bacteria,1V058@1239|Firmicutes,4HE2H@91061|Bacilli,471BZ@74385|Gracilibacillus	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158310_k127_494480_4	485913.Krac_0700	6.498e-29	120.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi	2|Bacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1782,iSSON_1240.SSON_4131,iYO844.BSU11190	Semialdhyde_dh,Semialdhyde_dhC
SRR25158310_k127_494480_5	530564.Psta_2298	3.564e-28	119.0	COG0622@1|root,COG0622@2|Bacteria,2J04S@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158310_k127_494480_2	289376.THEYE_A1388	2.491e-47	176.0	COG0590@1|root,COG0590@2|Bacteria,3J0PE@40117|Nitrospirae	40117|Nitrospirae	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158310_k127_494480_1	1235803.C825_03673	1.017e-50	192.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,2FMGJ@200643|Bacteroidia,22WEB@171551|Porphyromonadaceae	976|Bacteroidetes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158310_k127_494480_0	1123070.KB899249_gene300	5.984e-56	208.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia,2IU3R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158310_k127_494480_3	1056512.D515_01477	4.116e-41	157.0	COG0406@1|root,COG0406@2|Bacteria,1N1NR@1224|Proteobacteria,1SBM5@1236|Gammaproteobacteria,1Y0P4@135623|Vibrionales	135623|Vibrionales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158310_k127_494480_6	945550.VISI1226_06004	1.879e-11	70.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XT6V@135623|Vibrionales	135623|Vibrionales	H	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB	btuB	GO:0003674,GO:0005215	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158310_k127_50301_0	215803.DB30_4326	3.106e-127	419.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YU7C@29|Myxococcales	28221|Deltaproteobacteria	KL	helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
SRR25158310_k127_50301_1	1499967.BAYZ01000013_gene6463	3.35e-36	141.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
SRR25158310_k127_508208_3	1379281.AVAG01000012_gene1490	3.916e-42	158.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2MGD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158310_k127_508208_4	583355.Caka_2391	6.572e-37	154.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,3K762@414999|Opitutae	414999|Opitutae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR25158310_k127_508208_2	1565314.OA34_08245	6.585e-48	183.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2YMCX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	lipid a biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158310_k127_508208_1	1150621.SMUL_2491	6.642e-67	239.0	COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,42R32@68525|delta/epsilon subdivisions,2YNVT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
SRR25158310_k127_508208_0	679201.HMPREF9334_01517	4.423e-142	469.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158310_k127_508223_2	443254.Marpi_0104	6.6e-87	291.0	COG0502@1|root,COG0502@2|Bacteria,2GCAT@200918|Thermotogae	200918|Thermotogae	C	Biotin and Thiamin Synthesis associated	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	iLJ478.TM1267	BATS,Radical_SAM
SRR25158310_k127_508223_0	1150469.RSPPHO_00585	1.82e-124	411.0	COG0486@1|root,COG0486@2|Bacteria,1PM94@1224|Proteobacteria,2U0C7@28211|Alphaproteobacteria,2JV9N@204441|Rhodospirillales	204441|Rhodospirillales	S	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
SRR25158310_k127_508223_1	747365.Thena_1511	1.161e-108	359.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,42FS1@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM fumarate lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS20875	FumaraseC_C,Lyase_1
SRR25158310_k127_508503_1	1121396.KB892913_gene140	1.12e-61	222.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MPM4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
SRR25158310_k127_508503_0	583355.Caka_2526	0.0	1092.0	COG2838@1|root,COG2838@2|Bacteria,46TNM@74201|Verrucomicrobia,3K755@414999|Opitutae	414999|Opitutae	C	Isocitrate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
SRR25158310_k127_512110_0	583355.Caka_2355	3.198e-179	572.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158310_k127_512110_1	570268.ANBB01000002_gene325	2.232e-97	327.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4EFYC@85012|Streptosporangiales	201174|Actinobacteria	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158310_k127_512335_1	439235.Dalk_5153	7.159e-07	60.0	COG2165@1|root,COG2165@2|Bacteria,1R09J@1224|Proteobacteria,43CSN@68525|delta/epsilon subdivisions,2X80B@28221|Deltaproteobacteria,2MPMU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158310_k127_512335_0	123214.PERMA_0817	2.698e-07	61.0	COG3156@1|root,COG3156@2|Bacteria,2G4SA@200783|Aquificae	200783|Aquificae	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
SRR25158310_k127_513967_1	717785.HYPMC_3137	9.539e-29	134.0	COG0438@1|root,COG0438@2|Bacteria,1MVKB@1224|Proteobacteria,2U53J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_513967_0	1173028.ANKO01000148_gene1366	5.746e-46	188.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_526807_2	759914.BP951000_2310	2.435e-19	103.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158310_k127_526807_1	1313304.CALK_1423	7.534e-90	308.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_526807_0	926561.KB900617_gene2066	2.433e-139	450.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158310_k127_551404_0	760011.Spico_1805	5.815e-242	757.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,2J5QV@203691|Spirochaetes	203691|Spirochaetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158310_k127_551404_2	344747.PM8797T_29283	2.477e-110	373.0	COG1251@1|root,COG2146@1|root,COG1251@2|Bacteria,COG2146@2|Bacteria,2IY23@203682|Planctomycetes	203682|Planctomycetes	C	nitrite reductase (NAD(P)H) large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Rieske_2
SRR25158310_k127_551404_1	1027273.GZ77_01295	2.637e-159	511.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XI4A@135619|Oceanospirillales	135619|Oceanospirillales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158310_k127_551404_3	391937.NA2_16418	1.844e-46	169.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,2TR3T@28211|Alphaproteobacteria,43JU0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
SRR25158310_k127_557967_1	351160.RCIX1144	2.657e-78	265.0	COG0450@1|root,arCOG00312@2157|Archaea,2XYCY@28890|Euryarchaeota	28890|Euryarchaeota	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158310_k127_557967_2	765952.PUV_10050	3.566e-76	263.0	COG0266@1|root,COG0266@2|Bacteria,2JGIB@204428|Chlamydiae	204428|Chlamydiae	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158310_k127_557967_0	1122134.KB893650_gene1314	7.849e-148	475.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,1XHT2@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
SRR25158310_k127_557967_4	1403819.BATR01000087_gene2551	1.786e-27	128.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,46T3W@74201|Verrucomicrobia,2IUFR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158310_k127_557967_6	1335760.ASTG01000016_gene104	2.321e-08	66.0	COG0438@1|root,COG0438@2|Bacteria,1RBYC@1224|Proteobacteria,2U6QI@28211|Alphaproteobacteria,2K978@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_557967_7	102125.Xen7305DRAFT_00042130	0.0001084	54.0	COG0457@1|root,COG0457@2|Bacteria,1G07G@1117|Cyanobacteria,3VHPN@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
SRR25158310_k127_557967_3	237368.SCABRO_03716	1.271e-31	129.0	COG0735@1|root,COG0735@2|Bacteria,2IZJY@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158310_k127_557967_5	1121918.ARWE01000001_gene2164	1.851e-19	88.0	COG2221@1|root,COG2221@2|Bacteria,1QXPA@1224|Proteobacteria,42X12@68525|delta/epsilon subdivisions,2X7FG@28221|Deltaproteobacteria,43VYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	frx-2	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1033	Fer4
SRR25158310_k127_560352_1	857293.CAAU_1559	1.123e-40	155.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,36EFV@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
SRR25158310_k127_560352_0	313628.LNTAR_18800	3.238e-61	221.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,YojJ
SRR25158310_k127_560352_2	1379858.N508_01359	1.088e-11	74.0	COG4856@1|root,COG4856@2|Bacteria,2GFJV@200930|Deferribacteres	200930|Deferribacteres	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158310_k127_565057_2	1125863.JAFN01000001_gene88	1.639e-14	74.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158310_k127_565057_1	1196031.ALEG01000059_gene5500	3.928e-61	219.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158310_k127_565057_0	439235.Dalk_2506	1.484e-157	501.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MHVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158310_k127_566823_0	497964.CfE428DRAFT_2289	3.286e-101	342.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158310_k127_566823_1	1210908.HSB1_05660	2.709e-09	64.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTQI@28890|Euryarchaeota,23SY3@183963|Halobacteria	183963|Halobacteria	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158310_k127_56733_0	1131269.AQVV01000043_gene1801	6.517e-191	604.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE2	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	GAF,T2SSE,T2SSE_N
SRR25158310_k127_56733_1	1131269.AQVV01000011_gene2516	3.04e-50	183.0	COG1206@1|root,COG1206@2|Bacteria	2|Bacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158310_k127_567914_3	1131269.AQVV01000003_gene666	1.956e-85	299.0	COG0728@1|root,COG0728@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158310_k127_567914_2	382464.ABSI01000006_gene853	2.338e-98	332.0	COG0774@1|root,COG0774@2|Bacteria	2|Bacteria	M	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	lpxC	-	3.5.1.108,4.2.1.59	ko:K02535,ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	LpxC
SRR25158310_k127_567914_4	521045.Kole_0362	1.551e-73	248.0	COG0432@1|root,COG0432@2|Bacteria,2GCWD@200918|Thermotogae	200918|Thermotogae	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158310_k127_567914_0	1449050.JNLE01000003_gene940	9.116e-130	435.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158310_k127_567914_1	1122223.KB890701_gene2279	6.344e-116	389.0	COG1132@1|root,COG1132@2|Bacteria,1WJ5B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158310_k127_572296_0	644282.Deba_0604	8.635e-88	299.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158310_k127_572296_1	338963.Pcar_3025	2.4e-70	245.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,43U5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158310_k127_572296_2	1167006.UWK_01844	3.759e-63	229.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2MJBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158310_k127_572296_3	1278309.KB907100_gene2056	4.362e-20	93.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1XMH4@135619|Oceanospirillales	135619|Oceanospirillales	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158310_k127_573967_0	1449063.JMLS01000043_gene6560	1.959e-193	619.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,26SRJ@186822|Paenibacillaceae	91061|Bacilli	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRR25158310_k127_573967_2	452637.Oter_2049	8.408e-88	317.0	COG2211@1|root,COG2211@2|Bacteria,46YMU@74201|Verrucomicrobia,3K7KX@414999|Opitutae	414999|Opitutae	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158310_k127_573967_1	620914.JH621258_gene1025	1.917e-101	351.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,1I86X@117743|Flavobacteriia,2YKXH@290174|Aquimarina	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_578789_0	1278307.KB906983_gene3927	6.901e-235	744.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,2QIXK@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158310_k127_578789_1	521674.Plim_3544	4.521e-114	374.0	COG0115@1|root,COG0115@2|Bacteria,2IY3N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158310_k127_578789_2	205918.Psyr_2067	7.061e-62	218.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1Z5G5@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	Q	ABC transporter, ATP-binding protein	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158310_k127_58479_0	926562.Oweho_2634	2.868e-114	375.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia,2PAAI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158310_k127_58479_1	1313304.CALK_1189	5.988e-70	243.0	COG2738@1|root,COG2738@2|Bacteria	2|Bacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
SRR25158310_k127_589167_5	649747.HMPREF0083_05703	8.018e-28	115.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,26S2G@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	cspR	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158310_k127_589167_0	247490.KSU1_C0857	7.789e-146	468.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158310_k127_589167_1	880073.Calab_2467	3.703e-96	323.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158310_k127_589167_4	237368.SCABRO_01881	2.311e-28	126.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_589167_3	497964.CfE428DRAFT_3459	8.551e-68	242.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
SRR25158310_k127_589167_2	1131269.AQVV01000007_gene1020	2.261e-69	247.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158310_k127_589167_6	1167006.UWK_00742	8.764e-13	79.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
SRR25158310_k127_589167_8	1121930.AQXG01000011_gene1748	1.909e-06	56.0	2E5Q4@1|root,330ER@2|Bacteria,4NUT9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_589167_7	1122931.AUAE01000001_gene773	1.376e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,22X3E@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
SRR25158310_k127_590052_2	1318628.MARLIPOL_01550	1.176e-46	175.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,467B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	yhdE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158310_k127_590052_3	1337936.IJ00_22865	1.133e-31	141.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158310_k127_590052_0	177437.HRM2_p00340	1.443e-120	413.0	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X75B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
SRR25158310_k127_590052_1	1209989.TepiRe1_1695	6.305e-84	300.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,42FVP@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Na Picotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
SRR25158310_k127_590052_4	313628.LNTAR_03794	1.204e-31	125.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.64	ko:K12447	ko00040,ko00052,ko00053,ko00520,ko01100,ko01130,map00040,map00052,map00053,map00520,map01100,map01130	M00014	R00289,R00502,R01381,R03077,R08845	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
SRR25158310_k127_594132_3	517418.Ctha_0865	5.675e-22	103.0	COG0668@1|root,COG0668@2|Bacteria,1FD89@1090|Chlorobi	1090|Chlorobi	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
SRR25158310_k127_594132_0	762903.Pedsa_2830	1.5e-323	1016.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158310_k127_594132_2	1121396.KB893013_gene3725	5.214e-67	245.0	COG1404@1|root,COG1404@2|Bacteria,1R8NA@1224|Proteobacteria,42QMP@68525|delta/epsilon subdivisions,2WM2P@28221|Deltaproteobacteria,2MI2K@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158310_k127_594132_1	580340.Tlie_1634	2.717e-189	600.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
SRR25158310_k127_596596_3	1121918.ARWE01000001_gene3535	1.941e-32	127.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,43TAH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SRR25158310_k127_596596_0	1122176.KB903555_gene3772	1.315e-43	161.0	COG0720@1|root,COG0720@2|Bacteria,4NRT5@976|Bacteroidetes,1IT05@117747|Sphingobacteriia	976|Bacteroidetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158310_k127_596596_1	497964.CfE428DRAFT_2894	1.496e-36	142.0	COG0780@1|root,COG0780@2|Bacteria,46SYQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158310_k127_596596_2	1519464.HY22_01215	4.777e-33	138.0	COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi	1090|Chlorobi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158310_k127_596596_4	452637.Oter_3618	4.269e-05	48.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,3K76Z@414999|Opitutae	414999|Opitutae	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158310_k127_597319_1	497964.CfE428DRAFT_5447	8.835e-46	171.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SRR25158310_k127_597319_0	1392502.JNIO01000008_gene2345	2.996e-103	348.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4H2Y4@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158310_k127_597319_3	1485545.JQLW01000009_gene151	3.302e-17	82.0	2EBXF@1|root,335WT@2|Bacteria,1NBD8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_597319_2	869213.JCM21142_72779	7.071e-24	104.0	COG1595@1|root,COG1595@2|Bacteria,4NHIK@976|Bacteroidetes,47WW7@768503|Cytophagia	976|Bacteroidetes	K	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_cc,Laminin_G_3
SRR25158310_k127_60015_1	530564.Psta_1941	0.0004386	50.0	COG1054@1|root,COG1054@2|Bacteria,2J4AW@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0176 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_60015_0	931626.Awo_c16770	8.234e-156	499.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,25WNE@186806|Eubacteriaceae	186801|Clostridia	C	Malate/L-lactate dehydrogenase	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
SRR25158310_k127_605910_1	641491.DND132_1096	3.735e-53	192.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158310_k127_605910_0	717231.Flexsi_1725	3.735e-67	233.0	COG0441@1|root,COG0441@2|Bacteria,2GEP2@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158310_k127_607553_0	604331.AUHY01000023_gene1652	6.295e-70	247.0	COG1922@1|root,COG1922@2|Bacteria,1WJJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRR25158310_k127_607553_1	1194972.MVAC_26527	4.699e-06	58.0	COG1807@1|root,COG1807@2|Bacteria,2H2FK@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_608485_0	1499967.BAYZ01000118_gene3300	6.471e-134	437.0	COG1454@1|root,COG1454@2|Bacteria,2NQ5W@2323|unclassified Bacteria	2|Bacteria	C	Iron-containing alcohol dehydrogenase	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714,ko:K13954	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
SRR25158310_k127_608485_1	1273538.G159_11045	3.995e-57	206.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26DNF@186818|Planococcaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158310_k127_608485_2	199310.c3384	3.093e-07	52.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,1RP7K@1236|Gammaproteobacteria,3XMK4@561|Escherichia	1236|Gammaproteobacteria	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltA	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	iECABU_c1320.ECABU_c30840	3D,MltA
SRR25158310_k127_612223_1	481448.Minf_0906	8.084e-45	169.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,37GJI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	LU	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SRR25158310_k127_612223_0	313628.LNTAR_12616	1.17e-163	533.0	COG0550@1|root,COG0550@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158310_k127_618770_2	1408473.JHXO01000010_gene3618	1.596e-09	60.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158310_k127_618770_1	1461580.CCAS010000008_gene1224	1.995e-24	117.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,4HPX3@91061|Bacilli,1ZIA7@1386|Bacillus	91061|Bacilli	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158310_k127_618770_0	338963.Pcar_2879	7.372e-114	374.0	COG1251@1|root,COG2146@1|root,COG1251@2|Bacteria,COG2146@2|Bacteria,1MW58@1224|Proteobacteria,42PSQ@68525|delta/epsilon subdivisions,2WKDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Pyr_redox_2
SRR25158310_k127_630463_0	1121918.ARWE01000001_gene1376	1.691e-244	778.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43S4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	MutS domain I	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158310_k127_631924_0	457398.HMPREF0326_00615	4.131e-69	241.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,42NVB@68525|delta/epsilon subdivisions,2WK6R@28221|Deltaproteobacteria,2M88C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
SRR25158310_k127_631924_2	305900.GV64_03600	7.367e-32	130.0	COG2824@1|root,COG2824@2|Bacteria,1N1JG@1224|Proteobacteria,1S98R@1236|Gammaproteobacteria,1XKGA@135619|Oceanospirillales	135619|Oceanospirillales	P	Alkylphosphonate utilization operon protein PhnA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_631924_1	1089547.KB913013_gene4663	3.281e-51	192.0	COG1501@1|root,COG1595@1|root,COG1501@2|Bacteria,COG1595@2|Bacteria,4NHIK@976|Bacteroidetes,47WW7@768503|Cytophagia	976|Bacteroidetes	K	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_cc,Laminin_G_3
SRR25158310_k127_635326_2	2423.NA23_0204145	4.509e-13	76.0	COG1609@1|root,COG1609@2|Bacteria,2GCB2@200918|Thermotogae	200918|Thermotogae	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158310_k127_635326_0	744872.Spica_0250	1.22e-105	354.0	COG1929@1|root,COG1929@2|Bacteria,2J5ZM@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158310_k127_635326_1	935948.KE386495_gene1456	3.824e-65	240.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,42FW8@68295|Thermoanaerobacterales	186801|Clostridia	G	glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158310_k127_646464_4	1036674.A28LD_1678	8.829e-09	64.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1RZ1A@1236|Gammaproteobacteria,2QGPM@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3
SRR25158310_k127_646464_3	1509403.GW12_27290	1.643e-80	274.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,3NIUI@468|Moraxellaceae	1236|Gammaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390	PdxJ
SRR25158310_k127_646464_2	880072.Desac_0729	1.552e-89	313.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MQB5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158310_k127_646464_0	880072.Desac_2907	1.9e-131	432.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria,2MRBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
SRR25158310_k127_646464_1	880073.Calab_3704	2.987e-113	372.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415,iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158310_k127_646740_2	1283300.ATXB01000001_gene1031	0.0007259	45.0	2AY1G@1|root,31Q37@2|Bacteria,1QIYW@1224|Proteobacteria,1TGVJ@1236|Gammaproteobacteria,1XGT8@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
SRR25158310_k127_646740_0	247490.KSU1_C0713	2.585e-207	653.0	COG1004@1|root,COG1004@2|Bacteria,2IXM4@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158310_k127_646740_1	1118235.CAJH01000027_gene1920	6.146e-18	85.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,1SCJU@1236|Gammaproteobacteria,1X879@135614|Xanthomonadales	135614|Xanthomonadales	S	RNA-binding protein	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
SRR25158310_k127_649928_1	221027.JO40_09695	2.335e-50	190.0	COG0475@1|root,COG0475@2|Bacteria,2J5WC@203691|Spirochaetes	203691|Spirochaetes	P	Sodium hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Na_H_Exchanger
SRR25158310_k127_649928_0	1499967.BAYZ01000074_gene2189	1.863e-62	224.0	COG0531@1|root,COG1762@1|root,COG0531@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K16263	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.3.13,4.A.2.1	-	-	AA_permease,AA_permease_2,Na_H_Exchanger,PTS_EIIA_2,TrkA_C,TrkA_N
SRR25158310_k127_651101_0	1125863.JAFN01000001_gene3113	0.0	1326.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,1MWBZ@1224|Proteobacteria,43AE9@68525|delta/epsilon subdivisions,2X5U3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N
SRR25158310_k127_661533_0	926567.TheveDRAFT_0793	1.034e-151	490.0	COG0172@1|root,COG0172@2|Bacteria,3T9VY@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158310_k127_661533_2	926550.CLDAP_29440	5.274e-34	133.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158310_k127_661533_3	459349.CLOAM1049	6.018e-29	127.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158310_k127_661533_1	1499967.BAYZ01000009_gene5298	1.1e-103	354.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
SRR25158310_k127_66524_0	1123274.KB899410_gene3507	6.779e-93	316.0	COG0531@1|root,COG1762@1|root,COG0531@2|Bacteria,COG1762@2|Bacteria,2J6QT@203691|Spirochaetes	203691|Spirochaetes	EGT	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,PTS_EIIA_2
SRR25158310_k127_665602_2	1121949.AQXT01000002_gene2573	0.0002412	49.0	2BPDT@1|root,32I5X@2|Bacteria,1Q1Q8@1224|Proteobacteria,2V9D7@28211|Alphaproteobacteria,440I3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_665602_1	1101191.KI912577_gene1273	2.452e-52	188.0	COG3631@1|root,COG3631@2|Bacteria,1RISB@1224|Proteobacteria,2UAAK@28211|Alphaproteobacteria,1JXU2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158310_k127_667260_2	682795.AciX8_3320	3.181e-05	56.0	COG4447@1|root,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158310_k127_667260_0	518766.Rmar_0942	5.169e-126	413.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1FJUB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158310_k127_667260_1	1313304.CALK_1522	4.766e-107	355.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158310_k127_671361_2	862908.BMS_3002	1.24e-23	112.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158310_k127_671361_0	862908.BMS_3003	2.393e-144	479.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158310_k127_671361_4	1156937.MFUM_170034	3.703e-09	63.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,37H11@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158310_k127_671361_1	1121430.JMLG01000009_gene437	4.466e-88	297.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158310_k127_671361_3	1298865.H978DRAFT_3233	3.381e-11	66.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,465EG@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158310_k127_674454_0	665571.STHERM_c21570	4.34e-99	327.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2J5JF@203691|Spirochaetes	203691|Spirochaetes	C	Oxaloacetate decarboxylase, alpha subunit	oadA	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158310_k127_674454_1	237368.SCABRO_02515	3.398e-53	196.0	COG0340@1|root,COG0340@2|Bacteria	2|Bacteria	H	biotin-[acetyl-CoA-carboxylase] ligase activity	birA	-	6.3.4.15	ko:K03523,ko:K03524	ko00780,ko01100,ko02010,map00780,map01100,map02010	M00581,M00582	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.88.1,2.A.88.2	-	-	BPL_C,BPL_LplA_LipB
SRR25158310_k127_674454_2	933262.AXAM01000014_gene284	1.154e-32	134.0	COG3584@1|root,COG3584@2|Bacteria,1NUBZ@1224|Proteobacteria,42ZKS@68525|delta/epsilon subdivisions,2WUSM@28221|Deltaproteobacteria,2MNAS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
SRR25158310_k127_674454_3	452637.Oter_2815	1.197e-07	55.0	COG0858@1|root,COG0858@2|Bacteria,46TBI@74201|Verrucomicrobia,3K885@414999|Opitutae	414999|Opitutae	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158310_k127_681776_0	1120985.AUMI01000006_gene2183	4.903e-64	226.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H2TK@909932|Negativicutes	909932|Negativicutes	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158310_k127_681776_3	56780.SYN_00233	4.576e-32	129.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2MQKD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158310_k127_681776_1	883112.HMPREF9707_01150	5.932e-46	169.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,27DV3@186827|Aerococcaceae	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158310_k127_681776_2	1173027.Mic7113_4249	8.794e-43	165.0	COG1434@1|root,COG1434@2|Bacteria,1G5MW@1117|Cyanobacteria,1HA5K@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158310_k127_681776_4	1313304.CALK_1933	3.959e-31	129.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,HDOD,PAS_3,PAS_4,PilJ
SRR25158310_k127_685721_1	635013.TherJR_1277	1.739e-75	258.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,260U5@186807|Peptococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158310_k127_685721_0	1049564.TevJSym_an00240	6.698e-179	575.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1J4RN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,STAS_2,Sulfate_transp
SRR25158310_k127_685721_3	443143.GM18_0093	1.629e-55	205.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43TU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SRR25158310_k127_685721_2	526222.Desal_0806	1.984e-56	200.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2M8EU@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I KDSA	aroG-2	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRR25158310_k127_689274_0	1156937.MFUM_920003	2.13e-145	474.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,37GCZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158310_k127_689274_1	1519464.HY22_03120	9.437e-46	171.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158310_k127_689642_2	1168034.FH5T_11455	1.723e-26	111.0	COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,2FMCS@200643|Bacteroidia	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158310_k127_689642_1	441620.Mpop_3711	5.698e-60	216.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,1JSY3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158310_k127_689642_0	517418.Ctha_1654	4.434e-88	302.0	COG0119@1|root,COG0119@2|Bacteria,1FD80@1090|Chlorobi	1090|Chlorobi	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
SRR25158310_k127_697893_1	247490.KSU1_D0996	4.871e-54	199.0	COG0564@1|root,COG0564@2|Bacteria,2IZ8N@203682|Planctomycetes	203682|Planctomycetes	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SRR25158310_k127_697893_0	714943.Mucpa_5864	1.245e-136	443.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
SRR25158310_k127_699639_1	1265503.KB905169_gene232	3.36e-151	486.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPBC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158310_k127_699639_0	861299.J421_2772	2.237e-195	617.0	COG0050@1|root,COG0050@2|Bacteria,1ZSZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158310_k127_699639_2	768670.Calni_1535	2.401e-14	73.0	COG0267@1|root,COG0267@2|Bacteria,2GFZW@200930|Deferribacteres	200930|Deferribacteres	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158310_k127_713653_0	1229172.JQFA01000002_gene2509	6.952e-187	598.0	COG0370@1|root,COG0370@2|Bacteria,1G058@1117|Cyanobacteria,1H8CQ@1150|Oscillatoriales	1117|Cyanobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158310_k127_713653_2	1173026.Glo7428_1956	1.137e-15	81.0	COG1918@1|root,COG1918@2|Bacteria,1G74W@1117|Cyanobacteria	1117|Cyanobacteria	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SRR25158310_k127_713653_1	477974.Daud_0720	1.522e-18	86.0	2E9R1@1|root,333XB@2|Bacteria,1VGXW@1239|Firmicutes,24SHT@186801|Clostridia,265XU@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_715558_1	338963.Pcar_1338	4.14e-40	150.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2WQ2M@28221|Deltaproteobacteria,43V3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
SRR25158310_k127_715558_0	298386.PBPRB1676	4.535e-112	373.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,1XSX9@135623|Vibrionales	135623|Vibrionales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158310_k127_715858_1	269799.Gmet_2858	5.957e-78	267.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,42PUJ@68525|delta/epsilon subdivisions,2WM9G@28221|Deltaproteobacteria,43S2G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158310_k127_715858_2	497964.CfE428DRAFT_4070	1.2e-23	107.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158310_k127_715858_0	247490.KSU1_C0661	5.449e-131	430.0	COG0488@1|root,COG0488@2|Bacteria,2IX59@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158310_k127_719949_1	1120973.AQXL01000127_gene2748	2.848e-69	242.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,278AU@186823|Alicyclobacillaceae	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158310_k127_719949_0	756272.Plabr_2530	7.406e-162	522.0	COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158310_k127_724446_0	313628.LNTAR_24054	1.939e-126	413.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	ybiT	GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158310_k127_724446_1	552398.HMPREF0866_00690	3.443e-118	388.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGFI@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158310_k127_730667_2	309801.trd_0343	2.565e-33	139.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,27Y0Q@189775|Thermomicrobia	189775|Thermomicrobia	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158310_k127_730667_1	1173022.Cri9333_0100	1.415e-53	200.0	COG3021@1|root,COG3021@2|Bacteria,1G1V5@1117|Cyanobacteria,1HAVR@1150|Oscillatoriales	1117|Cyanobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158310_k127_730667_0	349741.Amuc_0683	5.508e-122	406.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia,2ITJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158310_k127_737186_2	1120999.JONM01000002_gene921	7.857e-55	200.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,2KPCX@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158310_k127_737186_1	313628.LNTAR_20358	4.177e-88	299.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158310_k127_737186_0	192952.MM_1885	7.597e-126	406.0	COG0019@1|root,arCOG02268@2157|Archaea,2XSY8@28890|Euryarchaeota,2N93Z@224756|Methanomicrobia	224756|Methanomicrobia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158310_k127_743556_0	439235.Dalk_4420	1.301e-16	80.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,42USJ@68525|delta/epsilon subdivisions,2WQ3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158310_k127_745812_2	314345.SPV1_00045	6.498e-85	286.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria	1224|Proteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158310_k127_745812_5	572544.Ilyop_1454	6.047e-40	161.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158310_k127_745812_1	243231.GSU2569	3.415e-86	297.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158310_k127_745812_7	452637.Oter_2716	1.673e-10	63.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia,3K8FH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_745812_3	1210884.HG799477_gene15426	4.449e-53	196.0	COG1187@1|root,COG1187@2|Bacteria,2IYUS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158310_k127_745812_4	383372.Rcas_3787	3.438e-45	171.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,3777D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158310_k127_745812_0	1403819.BATR01000134_gene4788	6.196e-109	363.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158310_k127_745812_6	439235.Dalk_2649	1.227e-12	68.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHW4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158310_k127_74682_3	381764.Fnod_0812	4.971e-25	105.0	2E32K@1|root,32Y2U@2|Bacteria,2GDGH@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_74682_1	313628.LNTAR_16798	1.745e-87	301.0	COG0079@1|root,COG0079@2|Bacteria	2|Bacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
SRR25158310_k127_74682_0	313628.LNTAR_08241	2.611e-117	391.0	COG0141@1|root,COG0141@2|Bacteria	2|Bacteria	E	histidinol dehydrogenase activity	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iUTI89_1310.UTI89_C2293,ic_1306.c2547	Histidinol_dh
SRR25158310_k127_74682_2	224324.aq_871	4.077e-36	145.0	COG0486@1|root,COG0486@2|Bacteria,2G3TR@200783|Aquificae	200783|Aquificae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158310_k127_756078_1	1047013.AQSP01000139_gene2339	9.291e-75	257.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
SRR25158310_k127_756078_0	869213.JCM21142_41533	2.208e-301	941.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
SRR25158310_k127_764793_2	1485545.JQLW01000010_gene1542	4.407e-35	139.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c45100	ThiC-associated,ThiC_Rad_SAM
SRR25158310_k127_764793_1	1334046.AYTB01000015_gene1516	1.593e-96	326.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,4HAGM@91061|Bacilli,26EB4@186818|Planococcaceae	91061|Bacilli	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30200	BATS,Radical_SAM
SRR25158310_k127_764793_0	313628.LNTAR_13422	3.249e-112	371.0	COG0042@1|root,COG0042@2|Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158310_k127_771501_0	313628.LNTAR_08151	0.0	1322.0	COG1049@1|root,COG1049@2|Bacteria	2|Bacteria	C	2-methylisocitrate dehydratase activity	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415	Aconitase,Aconitase_2_N,Aconitase_B_N
SRR25158310_k127_771501_2	1121948.AUAC01000003_gene2561	1.693e-47	184.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,43YAH@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	NAT, N-acetyltransferase, of N-acetylglutamate synthase	-	-	2.3.1.1,2.7.2.8	ko:K22478	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,NAT
SRR25158310_k127_771501_3	518766.Rmar_0874	1.02e-38	152.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1FJAZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158310_k127_771501_1	1123242.JH636434_gene4307	1.526e-138	455.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
SRR25158310_k127_786181_2	877414.ATWA01000003_gene384	6.34e-17	82.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,268S8@186813|unclassified Clostridiales	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158310_k127_786181_0	478741.JAFS01000001_gene1163	1.069e-91	311.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,37GF1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158310_k127_786181_1	481448.Minf_0410	4.004e-34	141.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,37G0C@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	nosY	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158310_k127_786523_3	865938.Weevi_0836	4.603e-29	120.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1HXBZ@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158310_k127_786523_1	1313172.YM304_27020	1.203e-45	179.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CN5X@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158310_k127_786523_2	926692.AZYG01000072_gene2721	4.779e-32	131.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WAWR@53433|Halanaerobiales	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158310_k127_786523_4	794903.OPIT5_05585	5.732e-21	100.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,3K75N@414999|Opitutae	414999|Opitutae	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158310_k127_786523_0	1307761.L21SP2_0801	2.685e-97	330.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158310_k127_79025_2	1454004.AW11_02074	6.54e-72	244.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1KQ7J@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158310_k127_79025_1	1121396.KB893058_gene2553	6.319e-111	369.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2WIZ8@28221|Deltaproteobacteria,2MIW8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
SRR25158310_k127_79025_0	1217712.F971_01417	6.333e-283	895.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,3NJ42@468|Moraxellaceae	1236|Gammaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_4025	PEPcase
SRR25158310_k127_790800_3	1121930.AQXG01000003_gene2777	1.681e-44	170.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
SRR25158310_k127_790800_1	349124.Hhal_1832	1.406e-57	207.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
SRR25158310_k127_790800_2	156889.Mmc1_1825	1.292e-44	170.0	2B79J@1|root,320CA@2|Bacteria,1N7TK@1224|Proteobacteria,2USKK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_790800_5	306281.AJLK01000058_gene1122	4.414e-27	114.0	COG0662@1|root,COG0662@2|Bacteria,1G6YF@1117|Cyanobacteria,1JIRW@1189|Stigonemataceae	1117|Cyanobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158310_k127_790800_0	56110.Oscil6304_2325	8.411e-77	267.0	COG1073@1|root,COG1073@2|Bacteria,1G2EP@1117|Cyanobacteria,1H83Z@1150|Oscillatoriales	1117|Cyanobacteria	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
SRR25158310_k127_790800_4	237368.SCABRO_02564	6.222e-39	154.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1,Memo
SRR25158310_k127_793137_2	1394176.AWUO01000001_gene1034	6.296e-36	138.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CZGN@85004|Bifidobacteriales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158310_k127_793137_3	345073.VC395_A0650	3.861e-22	105.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RNJC@1236|Gammaproteobacteria,1XVSG@135623|Vibrionales	135623|Vibrionales	S	phosphatase phosphohexomutase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158310_k127_793137_1	313628.LNTAR_15842	3.765e-44	168.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase_like
SRR25158310_k127_793137_0	65093.PCC7418_0297	1.649e-51	191.0	COG0602@1|root,COG0602@2|Bacteria,1G0HZ@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158310_k127_793334_8	926569.ANT_10040	1.237e-16	80.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158310_k127_793334_4	497964.CfE428DRAFT_0485	5.394e-49	176.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158310_k127_793334_0	944479.JQLX01000004_gene197	1.104e-247	783.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2M6MN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158310_k127_793334_3	481448.Minf_0680	9.66e-57	201.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,37GT5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158310_k127_793334_2	349741.Amuc_0308	2.094e-58	207.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,2IU8K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S12/S23	-	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158310_k127_793334_7	1535422.ND16A_1852	3.17e-31	123.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SWYX@1236|Gammaproteobacteria,2Q8BC@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Ribonuclease B OB domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR25158310_k127_793334_5	1120970.AUBZ01000009_gene2074	3.092e-41	159.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,467AH@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158310_k127_793334_1	525904.Tter_0314	2.895e-119	398.0	COG0165@1|root,COG0165@2|Bacteria,2NP70@2323|unclassified Bacteria	2|Bacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
SRR25158310_k127_793334_6	1461580.CCAS010000006_gene859	6.332e-37	141.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1ZG82@1386|Bacillus	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158310_k127_80303_1	313628.LNTAR_19802	4.325e-59	218.0	COG2974@1|root,COG2974@2|Bacteria	2|Bacteria	L	May be involved in recombination	-	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
SRR25158310_k127_80303_0	443143.GM18_1310	2.924e-63	229.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria	2|Bacteria	QT	Acyl-homoserine-lactone synthase	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5
SRR25158310_k127_80303_2	1123242.JH636435_gene1246	1.791e-05	49.0	COG0589@1|root,COG0589@2|Bacteria,2J4FC@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158310_k127_804868_1	1232410.KI421414_gene2847	1.207e-44	173.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158310_k127_804868_0	419665.Maeo_1494	4.354e-95	319.0	COG0436@1|root,arCOG01133@2157|Archaea,2XU6A@28890|Euryarchaeota,23QJF@183939|Methanococci	183939|Methanococci	E	PFAM aminotransferase, class I and II	dapL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0010285,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033362,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158310_k127_818591_2	1378168.N510_00895	8.71e-65	226.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes	1239|Firmicutes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158310_k127_818591_7	1033837.WANG_0009	8.135e-46	169.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158310_k127_818591_4	395964.KE386496_gene842	6.793e-54	194.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,3NAIJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158310_k127_818591_9	386415.NT01CX_1131	9.198e-26	109.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,36JQ0@31979|Clostridiaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158310_k127_818591_5	497964.CfE428DRAFT_0503	1.888e-51	187.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158310_k127_818591_6	420246.GTNG_0124	4.564e-49	179.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1WGA3@129337|Geobacillus	91061|Bacilli	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158310_k127_818591_0	452637.Oter_0207	3.902e-138	452.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158310_k127_818591_3	1385510.N781_07860	1.131e-63	224.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,2Y9S1@289201|Pontibacillus	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158310_k127_818591_1	401526.TcarDRAFT_1018	1.838e-89	301.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158310_k127_818591_8	1506583.JQJY01000008_gene4068	1.366e-30	136.0	COG1595@1|root,COG2247@1|root,COG1595@2|Bacteria,COG2247@2|Bacteria,4NHIK@976|Bacteroidetes,1I7M2@117743|Flavobacteriia,2NVCE@237|Flavobacterium	976|Bacteroidetes	K	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_cc,Laminin_G_3
SRR25158310_k127_834623_1	189426.PODO_00205	7.507e-48	182.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,26QVV@186822|Paenibacillaceae	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158310_k127_834623_0	1089550.ATTH01000001_gene1839	1.086e-69	243.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1FIZN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158310_k127_834689_3	1397666.RS24_01665	0.0008002	42.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,4BQ3I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158310_k127_834689_2	868131.MSWAN_0839	1.156e-11	74.0	arCOG06670@1|root,arCOG06670@2157|Archaea,2Y5UU@28890|Euryarchaeota,23PUE@183925|Methanobacteria	183925|Methanobacteria	L	NERD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NERD
SRR25158310_k127_834689_1	1123392.AQWL01000001_gene1588	8.388e-41	156.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158310_k127_834689_0	1123070.KB899253_gene1034	2.664e-51	186.0	COG4807@1|root,COG4807@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	yehS	-	-	-	-	-	-	-	-	-	-	-	DUF1456
SRR25158310_k127_837188_3	439235.Dalk_3005	0.0001209	45.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MJYE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158310_k127_837188_2	1123242.JH636436_gene154	2.286e-05	55.0	COG1762@1|root,COG1762@2|Bacteria,2IZFY@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
SRR25158310_k127_837188_0	314230.DSM3645_15540	1.015e-99	336.0	COG0820@1|root,COG0820@2|Bacteria,2J228@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the radical SAM superfamily. RlmN family	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158310_k127_837188_1	867902.Ornrh_0788	1.352e-92	317.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158310_k127_837418_0	237368.SCABRO_01551	1.11e-254	799.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SRR25158310_k127_839477_0	1158345.JNLL01000001_gene99	4.186e-152	494.0	COG0064@1|root,COG0064@2|Bacteria,2G3P7@200783|Aquificae	200783|Aquificae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158310_k127_839477_1	478741.JAFS01000001_gene1191	2.848e-117	383.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,37FYA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158310_k127_841410_2	203124.Tery_0446	2.853e-21	95.0	COG0284@1|root,COG0284@2|Bacteria,1G2ED@1117|Cyanobacteria,1H7AP@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158310_k127_841410_0	583355.Caka_0769	1.207e-190	611.0	COG0366@1|root,COG0366@2|Bacteria,46U53@74201|Verrucomicrobia,3K9RB@414999|Opitutae	414999|Opitutae	G	SMART alpha amylase catalytic sub domain	-	-	2.4.1.7,3.2.1.1,5.4.99.16	ko:K00690,ko:K05343	ko00500,ko01100,map00500,map01100	-	R00803,R01557,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR25158310_k127_841410_1	583355.Caka_0770	1.854e-107	354.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
SRR25158310_k127_844648_1	481448.Minf_0242	6.227e-94	317.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,37G4T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
SRR25158310_k127_844648_0	1156937.MFUM_1020086	0.0	1052.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,37FWQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158310_k127_852469_1	240015.ACP_1088	6.946e-67	246.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158310_k127_852469_0	1313304.CALK_2043	5.532e-95	314.0	COG0502@1|root,COG0502@2|Bacteria	2|Bacteria	H	biotin synthase activity	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
SRR25158310_k127_863989_2	671143.DAMO_0636	1.495e-31	126.0	COG3093@1|root,COG3093@2|Bacteria,2NR60@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
SRR25158310_k127_863989_1	449447.MAE_38920	4.937e-35	135.0	COG3549@1|root,COG3549@2|Bacteria,1GB1B@1117|Cyanobacteria	1117|Cyanobacteria	S	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
SRR25158310_k127_863989_3	234267.Acid_1464	5.39e-28	122.0	2C1EG@1|root,2Z7MZ@2|Bacteria,3Y5JH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_863989_0	520709.F985_04056	1.035e-35	144.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,1RW9F@1236|Gammaproteobacteria,3NJTA@468|Moraxellaceae	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,rve,rve_3
SRR25158310_k127_864717_1	313628.LNTAR_12811	2.436e-182	584.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158310_k127_864717_4	1144275.COCOR_04284	5.92e-89	303.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRR25158310_k127_864717_2	246197.MXAN_6629	2.711e-120	402.0	COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,42PWM@68525|delta/epsilon subdivisions,2WK8M@28221|Deltaproteobacteria,2YVRZ@29|Myxococcales	28221|Deltaproteobacteria	EH	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
SRR25158310_k127_864717_7	293826.Amet_4063	5.181e-24	106.0	COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,24NG5@186801|Clostridia,36MC6@31979|Clostridiaceae	186801|Clostridia	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SRR25158310_k127_864717_8	1304885.AUEY01000072_gene1700	4.168e-13	82.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158310_k127_864717_3	497964.CfE428DRAFT_6327	6.867e-91	310.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the SIS family. GutQ KpsF subfamily	gutQ	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR25158310_k127_864717_5	247490.KSU1_D0520	1.58e-44	175.0	COG0616@1|root,COG0616@2|Bacteria,2IZIJ@203682|Planctomycetes	203682|Planctomycetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158310_k127_864717_9	373903.Hore_11020	2.97e-07	59.0	COG0739@1|root,COG1388@1|root,COG3409@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,COG3409@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia,3WB5G@53433|Halanaerobiales	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
SRR25158310_k127_864717_6	869213.JCM21142_83147	2.811e-37	153.0	COG0679@1|root,COG0679@2|Bacteria,4NX5F@976|Bacteroidetes	976|Bacteroidetes	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158310_k127_864717_0	382464.ABSI01000010_gene3639	1.519e-217	689.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia,2ITUF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158310_k127_867445_3	1499967.BAYZ01000073_gene2050	6.68e-30	121.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,Hydrolase,Hydrolase_like
SRR25158310_k127_867445_2	635013.TherJR_2593	1.582e-71	251.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,26144@186807|Peptococcaceae	186801|Clostridia	S	PFAM PHP domain	-	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158310_k127_867445_0	204669.Acid345_2258	3.319e-112	370.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria,2JIG6@204432|Acidobacteriia	204432|Acidobacteriia	F	SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158310_k127_867445_1	1140001.I571_02615	6.67e-84	288.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,4AZE3@81852|Enterococcaceae	91061|Bacilli	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158310_k127_867445_4	1298865.H978DRAFT_3209	3.089e-11	70.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,464EE@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Type II secretory pathway, component PulF	mshG	-	-	ko:K02505,ko:K12278	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158310_k127_882998_1	153948.NAL212_2886	1.968e-11	76.0	COG5652@1|root,COG5652@2|Bacteria,1PXXM@1224|Proteobacteria,2WD8C@28216|Betaproteobacteria,3740S@32003|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158310_k127_882998_0	635013.TherJR_0853	3.393e-89	304.0	COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,24CPA@186801|Clostridia,261EQ@186807|Peptococcaceae	186801|Clostridia	C	oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158310_k127_885370_0	313628.LNTAR_22779	3.204e-95	321.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
SRR25158310_k127_885370_1	313628.LNTAR_17363	3.192e-52	196.0	COG1283@1|root,COG1283@2|Bacteria	2|Bacteria	P	sodium-dependent phosphate transmembrane transporter activity	phoU_1	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
SRR25158310_k127_886086_0	1123226.KB899317_gene1722	3.529e-31	134.0	COG1944@1|root,COG1944@2|Bacteria,1UYIC@1239|Firmicutes,4HDGN@91061|Bacilli,26U9N@186822|Paenibacillaceae	91061|Bacilli	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
SRR25158310_k127_886086_1	1455608.JDTH01000012_gene2160	2.217e-17	91.0	COG0476@1|root,arCOG01676@2157|Archaea,2Y2IP@28890|Euryarchaeota,23ZCK@183963|Halobacteria	183963|Halobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158310_k127_892497_0	497964.CfE428DRAFT_3169	4.361e-39	151.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
SRR25158310_k127_892497_1	523845.AQXV01000046_gene845	6.613e-38	152.0	COG0517@1|root,arCOG00607@2157|Archaea,2XTE5@28890|Euryarchaeota,23QM2@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR25158310_k127_892497_2	1396141.BATP01000059_gene2606	1.491e-36	147.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia,2ITX6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KQ	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
SRR25158310_k127_899204_0	880073.Calab_2574	2.884e-98	325.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158310_k127_899204_3	314282.PCNPT3_08975	0.0005437	49.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,2QHX7@267894|Psychromonadaceae	1236|Gammaproteobacteria	M	AsmA-like C-terminal region	asmA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
SRR25158310_k127_899204_1	316067.Geob_0816	1.629e-42	163.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,43UMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158310_k127_899204_2	452637.Oter_2230	1.005e-18	89.0	COG0240@1|root,COG0240@2|Bacteria,46UHW@74201|Verrucomicrobia,3K7IP@414999|Opitutae	414999|Opitutae	I	glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158310_k127_901751_0	1151127.KB906325_gene5134	4.291e-156	503.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1YPEK@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	DNA recombination protein RmuC	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158310_k127_901751_1	933262.AXAM01000047_gene2346	1.264e-90	308.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,2MHYQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
SRR25158310_k127_901751_2	76869.PputGB1_2388	4.199e-19	95.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,1RPZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4
SRR25158310_k127_903737_0	697282.Mettu_4376	2.79e-122	394.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XDNE@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158310_k127_905445_1	563192.HMPREF0179_01616	2.461e-100	334.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158310_k127_905445_2	1121405.dsmv_0406	4.363e-99	330.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
SRR25158310_k127_905445_0	247490.KSU1_C1335	1.794e-113	373.0	COG0379@1|root,COG0379@2|Bacteria,2IXB1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158310_k127_910341_1	1304880.JAGB01000002_gene1607	2.015e-35	139.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,24MBN@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158310_k127_910341_0	203122.Sde_2497	9.958e-73	254.0	COG1472@1|root,COG2755@1|root,COG1472@2|Bacteria,COG2755@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,465BV@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Lipase_GDSL_2
SRR25158310_k127_910341_2	180332.JTGN01000026_gene1580	1.459e-28	130.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158310_k127_913533_0	1396141.BATP01000056_gene3202	2.048e-71	263.0	COG0472@1|root,COG0472@2|Bacteria,46SNJ@74201|Verrucomicrobia,2IW0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
SRR25158310_k127_920496_2	331869.BAL199_19426	9.346e-20	93.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,4BQKE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158310_k127_920496_3	555779.Dthio_PD0584	0.0001124	53.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,42XAV@68525|delta/epsilon subdivisions,2WSJJ@28221|Deltaproteobacteria,2M7R0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
SRR25158310_k127_920496_0	497964.CfE428DRAFT_5284	4.339e-63	233.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,46SSK@74201|Verrucomicrobia	74201|Verrucomicrobia	U	WD40-like Beta Propeller Repeat	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158310_k127_920496_1	1123355.JHYO01000013_gene1120	1.02e-29	125.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,36Y72@31993|Methylocystaceae	28211|Alphaproteobacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158310_k127_936330_4	439235.Dalk_2393	5.497e-73	251.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158310_k127_936330_2	1005994.GTGU_02230	1.037e-80	282.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
SRR25158310_k127_936330_9	2340.JV46_04270	5.025e-22	99.0	COG2940@1|root,COG2940@2|Bacteria,1N2WJ@1224|Proteobacteria	1224|Proteobacteria	S	pfam set	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158310_k127_936330_0	498761.HM1_1297	0.0	1129.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158310_k127_936330_12	1396418.BATQ01000043_gene6438	4.075e-11	66.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158310_k127_936330_6	573061.Clocel_3782	3.039e-66	238.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,36E02@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158310_k127_936330_3	1185766.DL1_17820	3.126e-78	268.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2XMQ0@285107|Thioclava	28211|Alphaproteobacteria	S	Lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158310_k127_936330_7	237368.SCABRO_00250	1.565e-64	235.0	COG0501@1|root,COG0501@2|Bacteria,2J0GY@203682|Planctomycetes	203682|Planctomycetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158310_k127_936330_5	497964.CfE428DRAFT_1800	1.378e-66	239.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158310_k127_936330_11	8090.ENSORLP00000004807	7.625e-13	72.0	KOG1759@1|root,KOG1759@2759|Eukaryota,3A3MR@33154|Opisthokonta,3BRTB@33208|Metazoa,3D8KQ@33213|Bilateria,48ERS@7711|Chordata,49BE6@7742|Vertebrata,4A43I@7898|Actinopterygii	33208|Metazoa	V	macrophage migration inhibitory factor	MIF	GO:0000003,GO:0000302,GO:0001516,GO:0001666,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0001942,GO:0001976,GO:0001990,GO:0002016,GO:0002020,GO:0002035,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002673,GO:0002675,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002686,GO:0002688,GO:0002689,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002718,GO:0002720,GO:0002791,GO:0002793,GO:0002819,GO:0002821,GO:0002831,GO:0002833,GO:0002902,GO:0002903,GO:0002905,GO:0002906,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003674,GO:0003824,GO:0004167,GO:0005102,GO:0005125,GO:0005126,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006109,GO:0006110,GO:0006140,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006950,GO:0006955,GO:0006974,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007283,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0007569,GO:0007584,GO:0007610,GO:0007631,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0008283,GO:0008284,GO:0008544,GO:0008610,GO:0009058,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009611,GO:0009612,GO:0009617,GO:0009628,GO:0009636,GO:0009719,GO:0009725,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010469,GO:0010562,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010738,GO:0010739,GO:0010758,GO:0010760,GO:0010827,GO:0010828,GO:0010941,GO:0010948,GO:0010959,GO:0010975,GO:0010976,GO:0012505,GO:0014070,GO:0014910,GO:0014911,GO:0016043,GO:0016053,GO:0016192,GO:0016477,GO:0016853,GO:0016860,GO:0016862,GO:0016863,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019752,GO:0019899,GO:0019953,GO:0022008,GO:0022404,GO:0022405,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030141,GO:0030154,GO:0030330,GO:0030334,GO:0030335,GO:0030336,GO:0030545,GO:0030808,GO:0030810,GO:0030811,GO:0030813,GO:0030888,GO:0030890,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031344,GO:0031346,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031664,GO:0031666,GO:0031667,GO:0031960,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032103,GO:0032268,GO:0032269,GO:0032270,GO:0032303,GO:0032305,GO:0032306,GO:0032308,GO:0032355,GO:0032368,GO:0032370,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032570,GO:0032572,GO:0032642,GO:0032680,GO:0032722,GO:0032760,GO:0032787,GO:0032868,GO:0032879,GO:0032880,GO:0032890,GO:0032892,GO:0032940,GO:0032944,GO:0032946,GO:0033032,GO:0033033,GO:0033135,GO:0033138,GO:0033197,GO:0033273,GO:0033554,GO:0033559,GO:0033674,GO:0033993,GO:0034097,GO:0034599,GO:0034614,GO:0034762,GO:0034764,GO:0034774,GO:0035556,GO:0035690,GO:0035722,GO:0036230,GO:0036293,GO:0036294,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0042056,GO:0042060,GO:0042119,GO:0042127,GO:0042221,GO:0042287,GO:0042289,GO:0042303,GO:0042325,GO:0042327,GO:0042330,GO:0042493,GO:0042542,GO:0042633,GO:0042756,GO:0042770,GO:0042802,GO:0042981,GO:0043030,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043299,GO:0043312,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043434,GO:0043436,GO:0043467,GO:0043470,GO:0043516,GO:0043518,GO:0043549,GO:0043588,GO:0043900,GO:0043902,GO:0043933,GO:0044070,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044877,GO:0045055,GO:0045321,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045786,GO:0045787,GO:0045821,GO:0045859,GO:0045860,GO:0045913,GO:0045935,GO:0045937,GO:0045981,GO:0046324,GO:0046326,GO:0046394,GO:0046456,GO:0046457,GO:0046677,GO:0046903,GO:0048018,GO:0048145,GO:0048146,GO:0048232,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0048679,GO:0048680,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050178,GO:0050670,GO:0050671,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050727,GO:0050729,GO:0050730,GO:0050731,GO:0050767,GO:0050769,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050864,GO:0050865,GO:0050867,GO:0050871,GO:0050877,GO:0050886,GO:0050896,GO:0050900,GO:0050918,GO:0050920,GO:0050922,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051194,GO:0051196,GO:0051197,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051259,GO:0051260,GO:0051270,GO:0051271,GO:0051272,GO:0051338,GO:0051347,GO:0051384,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051960,GO:0051962,GO:0060205,GO:0060255,GO:0060284,GO:0060322,GO:0060429,GO:0060548,GO:0061078,GO:0061081,GO:0062012,GO:0062013,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070206,GO:0070207,GO:0070228,GO:0070229,GO:0070301,GO:0070372,GO:0070374,GO:0070482,GO:0070570,GO:0070572,GO:0070663,GO:0070665,GO:0070671,GO:0070887,GO:0071156,GO:0071157,GO:0071236,GO:0071310,GO:0071345,GO:0071349,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0072330,GO:0072331,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090237,GO:0090238,GO:0090342,GO:0090344,GO:0097237,GO:0097708,GO:0098772,GO:0098773,GO:0099503,GO:0101002,GO:0120035,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901568,GO:1901570,GO:1901576,GO:1901652,GO:1901654,GO:1901698,GO:1901700,GO:1901701,GO:1901796,GO:1901797,GO:1902165,GO:1902166,GO:1902229,GO:1902230,GO:1902253,GO:1902254,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1903578,GO:1903580,GO:1903793,GO:1904813,GO:1904951,GO:1905521,GO:1905522,GO:1905952,GO:1905954,GO:2000026,GO:2000106,GO:2000107,GO:2000145,GO:2000146,GO:2000147,GO:2000191,GO:2000193,GO:2000341,GO:2000343,GO:2001020,GO:2001021,GO:2001169,GO:2001171,GO:2001233,GO:2001234,GO:2001242,GO:2001243	5.3.2.1	ko:K07253	ko00350,ko00360,map00350,map00360	-	R01378,R03342	RC00507	ko00000,ko00001,ko01000,ko04147	-	-	-	MIF
SRR25158310_k127_936330_13	477974.Daud_1018	2.095e-06	56.0	COG1302@1|root,COG1302@2|Bacteria,1VF8P@1239|Firmicutes,24R1D@186801|Clostridia,2632Y@186807|Peptococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158310_k127_936330_10	445335.CBN_1950	1.434e-17	87.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,36KNG@31979|Clostridiaceae	186801|Clostridia	S	Alkaline shock protein	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158310_k127_936330_1	235909.GK2399	2.615e-91	305.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1WFQ3@129337|Geobacillus	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158310_k127_938248_0	903818.KI912268_gene1399	3.533e-173	561.0	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158310_k127_939965_0	868864.Dester_0385	4.681e-123	402.0	COG2804@1|root,COG2804@2|Bacteria,2G4H7@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158310_k127_942054_2	1121441.AUCX01000005_gene1398	9.016e-63	218.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158310_k127_942054_0	56110.Oscil6304_4438	7.402e-187	609.0	COG0531@1|root,COG0531@2|Bacteria,1G248@1117|Cyanobacteria,1H8SD@1150|Oscillatoriales	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
SRR25158310_k127_942054_1	1303518.CCALI_02577	4.268e-151	486.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SRR25158310_k127_945055_0	675817.VDA_001646	7.317e-179	570.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1XVRN@135623|Vibrionales	135623|Vibrionales	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158310_k127_945055_1	1123070.KB899257_gene2262	9.735e-60	211.0	COG0579@1|root,COG0579@2|Bacteria,46TYM@74201|Verrucomicrobia,2IU0Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Malate:quinone oxidoreductase (Mqo)	-	-	-	-	-	-	-	-	-	-	-	-	Mqo
SRR25158310_k127_949342_0	1121898.Q766_08715	3.681e-94	313.0	COG0463@1|root,COG0463@2|Bacteria,4NEQK@976|Bacteroidetes,1IMIV@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158310_k127_949342_2	435590.BVU_2656	6.133e-60	212.0	COG0110@1|root,COG0110@2|Bacteria,4NMZ2@976|Bacteroidetes,2FR4P@200643|Bacteroidia,4ARZ0@815|Bacteroidaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	wcaF	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
SRR25158310_k127_949342_1	717785.HYPMC_3134	1.863e-88	304.0	COG0438@1|root,COG0438@2|Bacteria,1MWEM@1224|Proteobacteria,2U1NW@28211|Alphaproteobacteria,3N8M7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_949342_3	1249480.B649_08430	3.708e-33	131.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2YMNJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158310_k127_950363_0	481448.Minf_0366	1.096e-89	301.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,37FZB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158310_k127_950363_1	497964.CfE428DRAFT_2954	7.644e-37	144.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia	74201|Verrucomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158310_k127_950363_2	387631.Asulf_02094	2.641e-32	127.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,246RY@183980|Archaeoglobi	183980|Archaeoglobi	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158310_k127_96009_1	1304885.AUEY01000005_gene879	1.981e-29	124.0	COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158310_k127_96009_0	273068.TTE1619	1.152e-105	357.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,42F2X@68295|Thermoanaerobacterales	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158310_k127_960532_1	278957.ABEA03000189_gene952	2.024e-35	140.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,3K7US@414999|Opitutae	414999|Opitutae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158310_k127_960532_0	583355.Caka_2492	2.637e-98	332.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158310_k127_967062_4	647113.Metok_0009	3.491e-34	135.0	COG0454@1|root,arCOG00826@2157|Archaea,2Y240@28890|Euryarchaeota,23RMS@183939|Methanococci	183939|Methanococci	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158310_k127_967062_3	1265505.ATUG01000003_gene555	6.876e-48	181.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42MZE@68525|delta/epsilon subdivisions,2WKJB@28221|Deltaproteobacteria,2MJDV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iAF987.Gmet_0512	SBP_bac_11
SRR25158310_k127_967062_0	862965.PARA_19460	3.974e-76	262.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1Y6VF@135625|Pasteurellales	135625|Pasteurellales	P	Molybdenum transport system permease protein ModB	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158310_k127_967062_2	583345.Mmol_2130	1.963e-59	213.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,2KNJF@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
SRR25158310_k127_967062_1	313628.LNTAR_10551	1.256e-68	238.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0008942,GO:0009061,GO:0009344,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0020037,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044464,GO:0045333,GO:0046857,GO:0046906,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051536,GO:0051540,GO:0055114,GO:0097159,GO:0098809,GO:1901265,GO:1901363	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3849	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Rieske_2
SRR25158310_k127_970558_0	1449126.JQKL01000016_gene2859	1.629e-71	250.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
SRR25158310_k127_978216_1	518766.Rmar_0739	2.339e-78	269.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1FJU9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158310_k127_978216_0	243233.MCA0169	7.971e-82	280.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1XDQ8@135618|Methylococcales	135618|Methylococcales	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158310_k127_978216_2	517418.Ctha_0655	1.002e-30	124.0	COG1132@1|root,COG1132@2|Bacteria,1FEQB@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC transporter related	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158310_k127_987277_2	1499967.BAYZ01000073_gene2050	1e-25	114.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,Hydrolase,Hydrolase_like
SRR25158310_k127_987277_0	314230.DSM3645_21809	8.534e-182	578.0	COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158310_k127_987277_1	1131462.DCF50_p892	1.631e-63	222.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,26732@186807|Peptococcaceae	186801|Clostridia	S	Conserved protein of DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158310_k127_990429_2	690850.Desaf_2362	0.0003634	51.0	COG2067@1|root,COG2067@2|Bacteria,1Q57F@1224|Proteobacteria,430QJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
SRR25158310_k127_990429_0	706587.Desti_3299	3.436e-110	372.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42MX0@68525|delta/epsilon subdivisions,2WM16@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRR25158310_k127_990429_1	882.DVU_0057	2.489e-31	129.0	COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,42MYP@68525|delta/epsilon subdivisions,2WKKZ@28221|Deltaproteobacteria,2MCQF@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator TetR	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
## 1155 queries scanned
## Total time (seconds): 34.67211675643921
## Rate: 33.31 q/s