## Sun Dec 14 01:55:11 2025 ## emapper-2.1.13 ## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158336_bin.4.fa -m mmseqs --itype genome -o SRR25158336_bin.4 --output_dir /data/result/bins/wyx/egg/SRR25158336_bin.4 --cpu 32 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs SRR25158336_k127_1001105_1 765913.ThidrDRAFT_1029 2.475e-34 133.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA SRR25158336_k127_1001105_0 472759.Nhal_0589 4.85e-137 441.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1WW8G@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SRR25158336_k127_1001105_2 65093.PCC7418_2764 2.117e-18 92.0 2E63H@1|root,330SK@2|Bacteria,1G9PE@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 SRR25158336_k127_1011249_1 713586.KB900536_gene1884 5.809e-189 602.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SRR25158336_k127_1011249_0 472759.Nhal_2479 4.795e-246 777.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WXWN@135613|Chromatiales 135613|Chromatiales I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 SRR25158336_k127_1011249_2 227377.CBU_0574 1.632e-13 70.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1JCSV@118969|Legionellales 118969|Legionellales I Thiolase, C-terminal domain yfcY - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR25158336_k127_1013391_0 1249627.D779_2733 2.315e-140 454.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1WWFA@135613|Chromatiales 135613|Chromatiales E PFAM Prephenate dehydratase - - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT SRR25158336_k127_1013391_1 572477.Alvin_2083 1.951e-138 449.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WXIX@135613|Chromatiales 135613|Chromatiales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SRR25158336_k127_1020179_2 631362.Thi970DRAFT_04864 3.791e-173 550.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales 135613|Chromatiales EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C SRR25158336_k127_1020179_1 396588.Tgr7_1536 1.058e-175 556.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 SRR25158336_k127_1020179_0 391615.ABSJ01000054_gene1428 0.0 1238.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1J52I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV SRR25158336_k127_1029402_0 713587.THITH_12355 3.034e-212 669.0 28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales 135613|Chromatiales S TIGRFAM carboxysome shell carbonic anhydrase - - - - - - - - - - - - CsoSCA SRR25158336_k127_1029402_1 1255043.TVNIR_2989 4.358e-86 289.0 28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,1WW4J@135613|Chromatiales 135613|Chromatiales S Carboxysome shell peptide mid-region - - - - - - - - - - - - CsoS2_M SRR25158336_k127_1031319_3 754477.Q7C_1770 6.356e-23 100.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,463KB@72273|Thiotrichales 72273|Thiotrichales M PFAM Transglycosylase SLT domain - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L SRR25158336_k127_1031319_0 472759.Nhal_0231 5.699e-110 364.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales 135613|Chromatiales GM NAD-dependent epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 SRR25158336_k127_1031319_1 396588.Tgr7_0331 8.871e-107 357.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales 135613|Chromatiales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd SRR25158336_k127_1031319_2 713586.KB900536_gene2506 8.885e-91 305.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1WW5C@135613|Chromatiales 135613|Chromatiales V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA SRR25158336_k127_1037651_0 765912.Thimo_0119 1.237e-212 673.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1WXQN@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A SRR25158336_k127_1037651_2 323261.Noc_2644 1.162e-118 389.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1WY5A@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR25158336_k127_1037651_3 472759.Nhal_0557 3.738e-79 274.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WXUC@135613|Chromatiales 135613|Chromatiales S ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 SRR25158336_k127_1037651_1 1198232.CYCME_0659 3.951e-143 467.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,46010@72273|Thiotrichales 72273|Thiotrichales N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux SRR25158336_k127_1038708_2 1049564.TevJSym_ag00550 8.283e-24 104.0 2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SD3Y@1236|Gammaproteobacteria,1J6YA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1038708_1 391165.GbCGDNIH1_0274 1.879e-31 126.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2UFDN@28211|Alphaproteobacteria,2JTWK@204441|Rhodospirillales 204441|Rhodospirillales P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - - - - - - - - - - Rieske SRR25158336_k127_1038708_0 765911.Thivi_2449 3.553e-84 286.0 COG1262@1|root,COG5185@1|root,COG1262@2|Bacteria,COG5185@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1X2B5@135613|Chromatiales 135613|Chromatiales NU PFAM Sulphatase-modifying factor - - - - - - - - - - - - FGE-sulfatase SRR25158336_k127_1048303_3 396588.Tgr7_2051 7.351e-41 154.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales 135613|Chromatiales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM SRR25158336_k127_1048303_2 1198232.CYCME_1996 3.051e-66 228.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,460K8@72273|Thiotrichales 72273|Thiotrichales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SRR25158336_k127_1048303_1 1283300.ATXB01000001_gene1604 4.615e-142 455.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1SKVW@1236|Gammaproteobacteria,1XDNK@135618|Methylococcales 135618|Methylococcales H Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - 6.2.1.9 ko:K08692 ko00630,ko00680,ko01120,ko01200,map00630,map00680,map01120,map01200 M00346 R01256 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SRR25158336_k127_1048303_0 156889.Mmc1_1747 2.777e-143 463.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA SRR25158336_k127_1048989_4 713586.KB900536_gene1370 2.373e-45 166.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1WWYB@135613|Chromatiales 135613|Chromatiales M Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SRR25158336_k127_1048989_3 472759.Nhal_0494 4.182e-50 189.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1X2GI@135613|Chromatiales 135613|Chromatiales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 SRR25158336_k127_1048989_0 314278.NB231_05571 3.222e-219 685.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales 135613|Chromatiales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA SRR25158336_k127_1048989_1 396588.Tgr7_0775 1.331e-167 534.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales 135613|Chromatiales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin SRR25158336_k127_1048989_2 1500890.JQNL01000001_gene1301 2.24e-77 261.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC SRR25158336_k127_1053094_0 713586.KB900536_gene1775 2.881e-45 177.0 COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L nuclease - - - - - - - - - - - - SNase SRR25158336_k127_1053094_1 1123368.AUIS01000005_gene471 4.123e-28 115.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,2ND6J@225057|Acidithiobacillales 225057|Acidithiobacillales J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 SRR25158336_k127_1053094_2 261292.Nit79A3_3507 2.212e-16 84.0 2EM8V@1|root,33EY0@2|Bacteria,1NJMD@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF3135) - - - - - - - - - - - - DUF3135 SRR25158336_k127_1053094_4 631362.Thi970DRAFT_02932 2.257e-11 67.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales 135613|Chromatiales O PFAM ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA SRR25158336_k127_1053094_5 713586.KB900536_gene1772 4.342e-05 49.0 COG4568@1|root,COG4568@2|Bacteria 2|Bacteria K rho-dependent transcription termination rof GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K19000 - - - - ko00000,ko03021 - - - ROF SRR25158336_k127_1053094_3 1500890.JQNL01000001_gene2604 3.798e-13 70.0 2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria,1X8YC@135614|Xanthomonadales 135614|Xanthomonadales S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG SRR25158336_k127_1054502_0 1049564.TevJSym_aj00500 1.345e-134 439.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1J50Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp SRR25158336_k127_1054502_1 1286106.MPL1_04817 1.755e-92 309.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,45ZRW@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 SRR25158336_k127_1054502_2 314345.SPV1_12415 5.916e-16 83.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria 1224|Proteobacteria M mechanosensitive ion channel aefA - - - - - - - - - - - MS_channel SRR25158336_k127_1057433_1 349124.Hhal_2226 2.965e-40 149.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales 135613|Chromatiales J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon SRR25158336_k127_1057433_2 1121937.AUHJ01000007_gene1900 2.36e-29 119.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,468ET@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 SRR25158336_k127_1057433_0 1049564.TevJSym_ax00430 1.606e-245 771.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,1J5MS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components atmA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SRR25158336_k127_1057433_3 1537994.JQFW01000001_gene3588 7.889e-06 54.0 COG3637@1|root,COG3637@2|Bacteria,1RK7I@1224|Proteobacteria,1S80S@1236|Gammaproteobacteria,46B41@72275|Alteromonadaceae 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain ax21 - - - - - - - - - - - OMP_b-brl SRR25158336_k127_1060401_5 402881.Plav_1122 3.273e-07 61.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UD20@28211|Alphaproteobacteria 28211|Alphaproteobacteria M surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Rick_17kDa_Anti SRR25158336_k127_1060401_2 1158292.JPOE01000005_gene882 1.93e-37 151.0 2C7AT@1|root,338A4@2|Bacteria,1NF74@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1060401_1 1158292.JPOE01000005_gene881 1.676e-46 175.0 COG0526@1|root,COG0526@2|Bacteria,1RIID@1224|Proteobacteria,2VUWV@28216|Betaproteobacteria,1KMES@119065|unclassified Burkholderiales 1224|Proteobacteria CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA SRR25158336_k127_1060401_3 498211.CJA_0607 2.935e-14 81.0 2EIP6@1|root,33CEJ@2|Bacteria,1NJA2@1224|Proteobacteria,1SHW0@1236|Gammaproteobacteria,1FHMC@10|Cellvibrio 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1060401_4 1118235.CAJH01000052_gene3087 1.006e-07 62.0 2EIP6@1|root,33CEJ@2|Bacteria,1NJA2@1224|Proteobacteria,1SHW0@1236|Gammaproteobacteria,1X8HN@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SRR25158336_k127_1060401_0 314278.NB231_10693 5.719e-88 299.0 COG0697@1|root,COG0697@2|Bacteria,1RJFE@1224|Proteobacteria,1RZF0@1236|Gammaproteobacteria,1WWYW@135613|Chromatiales 135613|Chromatiales EG EamA-like transporter family - - - - - - - - - - - - EamA SRR25158336_k127_1063473_0 338969.Rfer_1702 4.854e-104 349.0 COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,4ADVF@80864|Comamonadaceae 28216|Betaproteobacteria M HlyD family secretion protein - - - ko:K02005 - - - - ko00000 - - - HlyD_3 SRR25158336_k127_1063473_1 90814.KL370891_gene898 1.463e-71 247.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SRR25158336_k127_1065501_3 1049564.TevJSym_ak00800 1.262e-26 112.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1J6HN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG1544 Ribosome-associated protein Y (PSrp-1) yhbH GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE SRR25158336_k127_1065501_0 1323663.AROI01000003_gene2319 6.525e-171 549.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD SRR25158336_k127_1065501_1 187272.Mlg_2229 1.373e-103 342.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1WW0D@135613|Chromatiales 135613|Chromatiales S PFAM ABC transporter - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C SRR25158336_k127_1065501_4 472759.Nhal_0336 5.837e-25 112.0 COG1934@1|root,COG3103@1|root,COG1934@2|Bacteria,COG3103@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1WYD5@135613|Chromatiales 135613|Chromatiales T Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA,SH3_3 SRR25158336_k127_1065501_5 290398.Csal_2223 6.615e-07 59.0 COG3117@1|root,COG3117@2|Bacteria 2|Bacteria P lipopolysaccharide transmembrane transporter activity lptC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K02040,ko:K11719 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1,3.A.1.7 - iB21_1397.B21_03015,iECBD_1354.ECBD_0543,iECB_1328.ECB_03064,iECD_1391.ECD_03064 LptC SRR25158336_k127_1065501_2 1049564.TevJSym_ak00850 4.426e-68 233.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1J685@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECO26_1355.ECO26_4302 Hydrolase_3 SRR25158336_k127_10701_1 1286106.MPL1_01677 1.42e-53 193.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,460BE@72273|Thiotrichales 72273|Thiotrichales EGP major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like SRR25158336_k127_10701_0 243233.MCA2065 7.919e-184 580.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XEMR@135618|Methylococcales 135618|Methylococcales H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase SRR25158336_k127_1082575_1 1049564.TevJSym_ad00310 3.922e-103 349.0 2E6HP@1|root,3314Y@2|Bacteria,1QGPJ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1082575_0 1049564.TevJSym_aa01810 3.019e-301 931.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Citrate transporter sac1 - - - - - - - - - - - CitMHS,TrkA_C SRR25158336_k127_1085035_0 1384056.N787_05765 2.249e-87 295.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1X5K2@135614|Xanthomonadales 135614|Xanthomonadales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 SRR25158336_k127_1085035_3 292415.Tbd_1906 4.808e-11 72.0 2BXIA@1|root,2ZJ26@2|Bacteria,1P6T0@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1085035_1 84531.JMTZ01000054_gene1516 6.003e-86 292.0 COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,1X4VY@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF455 SRR25158336_k127_1085035_2 713586.KB900536_gene2981 1.302e-51 191.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales 135613|Chromatiales G pfam mofrl - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL SRR25158336_k127_1088312_0 472759.Nhal_1449 1.209e-214 679.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1WX4B@135613|Chromatiales 135613|Chromatiales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 SRR25158336_k127_1088394_2 926560.KE387025_gene3982 1.477e-77 269.0 COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR25158336_k127_1088394_1 1134413.ANNK01000144_gene3793 1.004e-100 337.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli,1ZB6V@1386|Bacillus 91061|Bacilli S -transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF SRR25158336_k127_1088394_0 402881.Plav_1858 5.654e-142 466.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,1JPG1@119043|Rhodobiaceae 28211|Alphaproteobacteria E GMC oxidoreductase - - - - - - - - - - - - DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 SRR25158336_k127_1090533_1 396588.Tgr7_1424 1.824e-09 65.0 COG0790@1|root,COG0790@2|Bacteria,1PE90@1224|Proteobacteria 1224|Proteobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 SRR25158336_k127_1090533_0 2340.JV46_20660 6.278e-274 853.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1J4NM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 SRR25158336_k127_1110120_1 1049564.TevJSym_ab01230 3.749e-90 304.0 COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H protein methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SRR25158336_k127_1110120_2 1232410.KI421421_gene3307 1.848e-52 190.0 COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,42SCJ@68525|delta/epsilon subdivisions,2WPGQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S CYTH - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CYTH SRR25158336_k127_1110120_0 236097.ADG881_1479 1.951e-170 542.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XI8T@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 - R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SRR25158336_k127_1113025_1 765911.Thivi_0987 6.479e-21 108.0 COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1WW9G@135613|Chromatiales 135613|Chromatiales J Zinc-ribbon containing domain - - - - - - - - - - - - DUF1451 SRR25158336_k127_1113025_0 396588.Tgr7_2279 0.0 1262.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales 135613|Chromatiales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SRR25158336_k127_1119495_2 709986.Deima_3288 1.926e-19 96.0 COG1749@1|root,COG4085@1|root,COG1749@2|Bacteria,COG4085@2|Bacteria 2|Bacteria S PFAM nucleic acid binding, OB-fold, tRNA flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C SRR25158336_k127_1119495_0 686340.Metal_3868 1.374e-57 207.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XF1Q@135618|Methylococcales 135618|Methylococcales J Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle - - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 SRR25158336_k127_1119495_1 1049564.TevJSym_bn00140 7.244e-53 189.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1J8GA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Amidohydrolase family pyrC - 3.5.2.3,3.5.2.5 ko:K01465,ko:K01466 ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120 M00051,M00546 R01993,R02425 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 SRR25158336_k127_1119583_0 396588.Tgr7_1362 3.983e-75 259.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1WXIP@135613|Chromatiales 135613|Chromatiales E Belongs to the agmatine deiminase family aguA - - - - - - - - - - - PAD_porph SRR25158336_k127_1119583_2 1384054.N790_00780 9.174e-15 78.0 2ENKU@1|root,33G87@2|Bacteria,1NMH6@1224|Proteobacteria,1SGDI@1236|Gammaproteobacteria,1X7KN@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SRR25158336_k127_1119583_1 396588.Tgr7_1852 4.211e-52 187.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1WW7E@135613|Chromatiales 135613|Chromatiales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus SRR25158336_k127_1119851_1 768671.ThimaDRAFT_0202 2.389e-46 169.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1WXJN@135613|Chromatiales 135613|Chromatiales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N SRR25158336_k127_1119851_0 1266925.JHVX01000008_gene319 1.492e-133 439.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3724V@32003|Nitrosomonadales 28216|Betaproteobacteria I acyl-CoA dehydrogenase fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 SRR25158336_k127_1124810_0 1283300.ATXB01000001_gene2393 1.494e-114 377.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1XE3K@135618|Methylococcales 135618|Methylococcales M PFAM YkuD domain - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - YkuD SRR25158336_k127_1124810_1 1266908.AQPB01000050_gene1843 1.938e-61 216.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria,1X1DX@135613|Chromatiales 135613|Chromatiales M 17 kDa outer membrane surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti SRR25158336_k127_1125781_1 2340.JV46_21420 1.994e-86 288.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1J9E0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3318 GDC-P SRR25158336_k127_1125781_2 768671.ThimaDRAFT_1573 2.137e-70 244.0 COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,1WX7S@135613|Chromatiales 135613|Chromatiales O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin SRR25158336_k127_1125781_0 768671.ThimaDRAFT_1574 5.585e-96 319.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1WWD2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P SRR25158336_k127_1126758_2 555778.Hneap_2121 4.119e-78 266.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWG5@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K09695 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC_tran SRR25158336_k127_1126758_8 1385517.N800_13175 7.088e-05 48.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,1X6T0@135614|Xanthomonadales 135614|Xanthomonadales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - SRR25158336_k127_1126758_3 247633.GP2143_13671 1.246e-50 180.0 COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,1JAT2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - ko:K09700 - - - - ko00000 - - - - SRR25158336_k127_1126758_1 1244869.H261_08788 2.992e-88 302.0 COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2TV6U@28211|Alphaproteobacteria,2JQ9F@204441|Rhodospirillales 204441|Rhodospirillales I Lysophospholipase - - - - - - - - - - - - Hydrolase_4 SRR25158336_k127_1126758_0 62928.azo0911 1.411e-92 308.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,2KV74@206389|Rhodocyclales 206389|Rhodocyclales S Belongs to the BI1 family - - - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I SRR25158336_k127_1126758_4 1163617.SCD_n02061 4.891e-35 138.0 2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,2W4PR@28216|Betaproteobacteria 28216|Betaproteobacteria S SseB protein N-terminal domain - - - - - - - - - - - - SseB SRR25158336_k127_1126758_5 713587.THITH_13795 3.078e-25 110.0 COG1266@1|root,COG1266@2|Bacteria,1ND7U@1224|Proteobacteria,1T0I9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SRR25158336_k127_1128033_4 395493.BegalDRAFT_1783 1.72e-32 131.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ccoH - - ko:K09926 - - - - ko00000 - - - FixH SRR25158336_k127_1128033_1 395493.BegalDRAFT_1784 2.704e-195 618.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4601I@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM cytochrome c oxidase accessory protein FixG - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C SRR25158336_k127_1128033_5 497321.C664_09793 5.915e-13 75.0 2EFX9@1|root,32YGP@2|Bacteria,1N7MN@1224|Proteobacteria,2VW9F@28216|Betaproteobacteria,2KXDY@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - SRR25158336_k127_1128033_2 375286.mma_1634 3.22e-110 364.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae 28216|Betaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N SRR25158336_k127_1128033_6 713587.THITH_06435 1.942e-10 63.0 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ SRR25158336_k127_1128033_3 1454004.AW11_01637 9.594e-96 317.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,1KQIV@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Cytochrome C oxidase, mono-heme subunit/FixO ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO SRR25158336_k127_1128033_0 397945.Aave_1523 2.245e-257 798.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,4AAKI@80864|Comamonadaceae 28216|Betaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 SRR25158336_k127_1128633_0 1163617.SCD_n02745 1.334e-85 286.0 COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria 28216|Betaproteobacteria P Cytochrome c554 and c-prime - - - - - - - - - - - - - SRR25158336_k127_1128633_1 1535422.ND16A_2692 1.406e-30 135.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome c cc4 - - - - - - - - - - - Cytochrom_C SRR25158336_k127_1128633_2 857087.Metme_0815 7.156e-10 62.0 293CN@1|root,2ZQV6@2|Bacteria,1RDZB@1224|Proteobacteria,1T0P9@1236|Gammaproteobacteria,1XE1D@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - SRR25158336_k127_1128771_4 754476.Q7A_19 1.955e-38 146.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,460WX@72273|Thiotrichales 72273|Thiotrichales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 SRR25158336_k127_1128771_0 396588.Tgr7_0439 6.705e-286 885.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales 135613|Chromatiales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 SRR25158336_k127_1128771_2 1298593.TOL_0220 4.253e-65 226.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XJJM@135619|Oceanospirillales 135619|Oceanospirillales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like SRR25158336_k127_1128771_3 2340.JV46_02650 2.04e-41 153.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1J6N0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S binding domain fdx1 - - - - - - - - - - - Fer4 SRR25158336_k127_1128771_1 713586.KB900536_gene2420 2.465e-218 693.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales 135613|Chromatiales E PFAM Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept SRR25158336_k127_1129063_1 314278.NB231_01219 5.395e-88 292.0 COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales 135613|Chromatiales C PFAM Phosphoribulokinase uridine kinase - - 2.7.1.19 ko:K00855 ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200 M00165,M00166 R01523 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK SRR25158336_k127_1129063_3 105559.Nwat_2276 3.22e-12 69.0 2EUGW@1|root,33MZ3@2|Bacteria,1NN50@1224|Proteobacteria,1SIVS@1236|Gammaproteobacteria,1X1RR@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_1129063_2 349521.HCH_06241 1.441e-21 102.0 COG1416@1|root,COG1416@2|Bacteria,1NAV2@1224|Proteobacteria,1SYA3@1236|Gammaproteobacteria,1XM9S@135619|Oceanospirillales 135619|Oceanospirillales - - - - - ko:K09004 - - - - ko00000 - - - DrsE SRR25158336_k127_1129063_0 1266925.JHVX01000001_gene2483 1.362e-113 377.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2WAY9@28216|Betaproteobacteria,371NX@32003|Nitrosomonadales 28216|Betaproteobacteria O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA SRR25158336_k127_1137796_3 243231.GSU0044 2.284e-10 66.0 COG3055@1|root,COG3209@1|root,COG3266@1|root,COG3291@1|root,COG4733@1|root,COG3055@2|Bacteria,COG3209@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Rhs family - - - - - - - - - - - - AHH,RHS_repeat,SpvB,TcdB_toxin_midN,VCBS SRR25158336_k127_1137796_0 870187.Thini_0151 1.148e-35 140.0 2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,1S614@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1137796_4 1158146.KB907123_gene690 7.387e-08 59.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SGKD@1236|Gammaproteobacteria,1WYKI@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 SRR25158336_k127_1137796_1 1122603.ATVI01000005_gene3224 9.978e-21 93.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1X83M@135614|Xanthomonadales 135614|Xanthomonadales J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA SRR25158336_k127_1138630_1 754476.Q7A_1386 2.114e-64 226.0 COG3784@1|root,COG3784@2|Bacteria,1MYIH@1224|Proteobacteria,1S8D2@1236|Gammaproteobacteria,462EF@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1318) - - - - - - - - - - - - DUF1318 SRR25158336_k127_1138630_0 1286106.MPL1_09907 4.881e-93 314.0 COG2911@1|root,COG2911@2|Bacteria,1MW9V@1224|Proteobacteria,1S3FX@1236|Gammaproteobacteria,461VT@72273|Thiotrichales 72273|Thiotrichales S Protein conserved in bacteria - - - - - - - - - - - - - SRR25158336_k127_1138862_2 911045.PSE_3128 1.761e-103 338.0 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2TTB5@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - COX2,Cupredoxin_1 SRR25158336_k127_1138862_1 1123366.TH3_08012 3.292e-145 471.0 COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,2TQTC@28211|Alphaproteobacteria,2JRC5@204441|Rhodospirillales 204441|Rhodospirillales P Periplasmic copper-binding protein (NosD) - - - ko:K07218 - - - - ko00000 - - - NosD SRR25158336_k127_1138862_3 670307.HYPDE_29158 2.234e-84 289.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TSI2@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC transporter nosF - - ko:K01990,ko:K19340 ko02010,map02010 M00254,M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 - - ABC_tran SRR25158336_k127_1138862_4 1038858.AXBA01000037_gene4812 5.464e-80 276.0 COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2U10D@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component nosY - - ko:K01992,ko:K19341 ko02010,map02010 M00254,M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 - - ABC2_membrane_2 SRR25158336_k127_1138862_0 1385935.N836_18235 6.868e-161 522.0 COG1283@1|root,COG1283@2|Bacteria,1G2NY@1117|Cyanobacteria 1117|Cyanobacteria P Na Pi-cotransporter family protein - - - - - - - - - - - - Na_Pi_cotrans SRR25158336_k127_1139066_1 754476.Q7A_2526 8.424e-77 262.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,460BE@72273|Thiotrichales 72273|Thiotrichales EGP major facilitator superfamily - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like SRR25158336_k127_1139066_0 472759.Nhal_0274 6.551e-193 608.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales 135613|Chromatiales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt SRR25158336_k127_1139066_3 765911.Thivi_0625 2.458e-08 59.0 2E5B5@1|root,33039@2|Bacteria,1NDK8@1224|Proteobacteria,1SFKE@1236|Gammaproteobacteria,1WZDR@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_1139066_2 765911.Thivi_0624 3.529e-26 109.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS SRR25158336_k127_114403_1 305700.B447_15831 3.41e-88 301.0 COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,2VRI5@28216|Betaproteobacteria 28216|Betaproteobacteria M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 SRR25158336_k127_114403_2 187272.Mlg_2791 1.592e-23 101.0 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1WZR6@135613|Chromatiales 135613|Chromatiales S Zinc-finger domain - - - - - - - - - - - - zf-CHCC SRR25158336_k127_114403_0 1049564.TevJSym_bj00030 2.738e-96 330.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1J4TI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980 ABC_membrane,ABC_tran SRR25158336_k127_1150414_1 1049564.TevJSym_ah00050 8.579e-49 178.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1J4MX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans SRR25158336_k127_1150414_2 1122197.ATWI01000009_gene1884 8.148e-42 161.0 COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,467AZ@72275|Alteromonadaceae 1236|Gammaproteobacteria S High frequency lysogenization protein HflD homolog hflD GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - ko:K07153 - - - - ko00000 - - - DUF489 SRR25158336_k127_1150414_0 519989.ECTPHS_03162 1.097e-312 973.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WW6D@135613|Chromatiales 135613|Chromatiales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C SRR25158336_k127_1153269_0 765914.ThisiDRAFT_2156 1.038e-131 423.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.4.1.1 ko:K01959 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 SRR25158336_k127_1153269_1 153948.NAL212_1105 8.698e-126 408.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria,373US@32003|Nitrosomonadales 28216|Betaproteobacteria C TIGRFAM Oxaloacetate decarboxylase, alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA SRR25158336_k127_1161437_9 631362.Thi970DRAFT_03834 3.019e-12 67.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1WYT7@135613|Chromatiales 135613|Chromatiales E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K08234 - - - - ko00000 - - - Glyoxalase SRR25158336_k127_1161437_5 2340.JV46_18770 1.038e-70 249.0 COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,1JBIJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SRR25158336_k127_1161437_1 472759.Nhal_2768 3.998e-177 563.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1WWET@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class I and II - - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SRR25158336_k127_1161437_2 396588.Tgr7_1152 1.97e-156 496.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1WVX8@135613|Chromatiales 135613|Chromatiales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 SRR25158336_k127_1161437_7 351348.Maqu_2552 6.062e-40 153.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,467VK@72275|Alteromonadaceae 1236|Gammaproteobacteria P Belongs to the ArsC family yffB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC SRR25158336_k127_1161437_0 396588.Tgr7_1150 1.359e-178 568.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1WWQK@135613|Chromatiales 135613|Chromatiales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 SRR25158336_k127_1161437_4 1163617.SCD_n01357 4.626e-82 283.0 COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria 1224|Proteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT SRR25158336_k127_1161437_3 1163617.SCD_n01356 4.782e-122 402.0 COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria 28216|Betaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP SRR25158336_k127_1161437_8 1049564.TevJSym_aa02520 2.753e-15 82.0 COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,1SD4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP-type C4-dicarboxylate transport system small permease component - - - - - - - - - - - - DctQ SRR25158336_k127_1161437_6 1163617.SCD_n01354 7.712e-55 198.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria 28216|Betaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM,DctQ SRR25158336_k127_1161645_0 396588.Tgr7_0871 6.653e-244 761.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1WXDW@135613|Chromatiales 135613|Chromatiales G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI SRR25158336_k127_1170203_4 768671.ThimaDRAFT_4052 6.041e-72 247.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B SRR25158336_k127_1170203_3 2340.JV46_08600 9.393e-74 254.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1J5WR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N SRR25158336_k127_1170203_0 765913.ThidrDRAFT_3407 2.656e-169 539.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SRR25158336_k127_1170203_1 1049564.TevJSym_bp00150 4.779e-141 453.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1J4QF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3,2.1.3.6,2.1.3.9 ko:K00611,ko:K09065,ko:K13252 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01398,R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N SRR25158336_k127_1170203_2 713586.KB900536_gene1264 2.905e-82 280.0 COG0121@1|root,COG0121@2|Bacteria,1PX9X@1224|Proteobacteria,1SBGN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glutamine amidotransferase egtC - - - - - - - - - - - GATase_4 SRR25158336_k127_1170203_5 713586.KB900536_gene1265 6.616e-17 87.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales 135613|Chromatiales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase SRR25158336_k127_1176418_4 1163617.SCD_n00544 4.66e-11 65.0 2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,2W41I@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1176418_2 672.VV93_v1c42870 3.982e-52 186.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 SRR25158336_k127_1176418_0 713586.KB900536_gene1677 2.762e-138 447.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales 135613|Chromatiales F SAICAR synthetase purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt SRR25158336_k127_1176418_1 396588.Tgr7_2885 8.963e-70 240.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1WY0E@135613|Chromatiales 135613|Chromatiales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC SRR25158336_k127_1176418_3 1123368.AUIS01000029_gene1282 2.344e-13 70.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,2NBXD@225057|Acidithiobacillales 225057|Acidithiobacillales F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp SRR25158336_k127_1177022_1 765913.ThidrDRAFT_2614 4.454e-163 521.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD SRR25158336_k127_1177022_0 572477.Alvin_1101 3.027e-207 650.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1WW7C@135613|Chromatiales 135613|Chromatiales E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 SRR25158336_k127_1177022_2 1182590.BN5_02526 1.341e-23 101.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA SRR25158336_k127_1177041_0 697282.Mettu_0374 8.273e-42 158.0 COG0517@1|root,COG0517@2|Bacteria,1QJRF@1224|Proteobacteria,1THSQ@1236|Gammaproteobacteria,1XFJQ@135618|Methylococcales 135618|Methylococcales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS SRR25158336_k127_1177041_1 1249627.D779_1426 1.685e-23 104.0 28T0P@1|root,2ZF9Z@2|Bacteria,1RAUV@1224|Proteobacteria,1S23D@1236|Gammaproteobacteria,1WY26@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_1182444_2 519989.ECTPHS_02676 7.204e-101 341.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1WVWX@135613|Chromatiales 135613|Chromatiales CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 SRR25158336_k127_1182444_0 1123399.AQVE01000002_gene2374 8.914e-156 502.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales 72273|Thiotrichales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C SRR25158336_k127_1182444_3 545276.KB898724_gene1942 3.815e-50 184.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1WYGS@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H SRR25158336_k127_1182444_1 768671.ThimaDRAFT_1574 1.309e-101 334.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1WWD2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P SRR25158336_k127_1190696_2 713586.KB900536_gene2898 5.965e-60 209.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - - - - - - - - - - - CCG SRR25158336_k127_1190696_1 713586.KB900536_gene2900 4.135e-70 242.0 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales 135613|Chromatiales C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 SRR25158336_k127_1190696_3 1049564.TevJSym_ak00390 6.61e-16 85.0 2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,1S4AH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S CNP1-like family - - - - - - - - - - - - CNP1 SRR25158336_k127_1190696_0 1049564.TevJSym_ad00780 1.613e-123 400.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim SRR25158336_k127_1191592_2 396588.Tgr7_0732 6.295e-93 314.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1WXKK@135613|Chromatiales 135613|Chromatiales P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex SRR25158336_k127_1191592_1 519989.ECTPHS_01719 3.917e-118 386.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1WW98@135613|Chromatiales 135613|Chromatiales Q PFAM ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran SRR25158336_k127_1191592_0 1286106.MPL1_06507 1.974e-120 391.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales 72273|Thiotrichales Q ABC transporter permease - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE SRR25158336_k127_1191592_3 472759.Nhal_0343 2.549e-51 186.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1WXYG@135613|Chromatiales 135613|Chromatiales Q PFAM Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD SRR25158336_k127_1191592_4 323261.Noc_2782 3.141e-35 139.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1WXHN@135613|Chromatiales 135613|Chromatiales Q PFAM toluene tolerance - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC SRR25158336_k127_1197869_1 472759.Nhal_2686 7.515e-72 247.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales 135613|Chromatiales H Belongs to the NadC ModD family - - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N SRR25158336_k127_1197869_3 1163617.SCD_n02057 3.853e-45 169.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria 28216|Betaproteobacteria G Peptidyl-prolyl cis-trans isomerase fkpA - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C SRR25158336_k127_1197869_0 396588.Tgr7_0799 1.009e-191 609.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1WXAG@135613|Chromatiales 135613|Chromatiales E PFAM sodium alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp SRR25158336_k127_1197869_4 1122201.AUAZ01000003_gene1978 1.507e-44 167.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,4674J@72275|Alteromonadaceae 1236|Gammaproteobacteria S aspartyl protease orf - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas SRR25158336_k127_1197869_2 396588.Tgr7_2475 8.208e-61 213.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q methyltransferase egtB - - - - - - - - - - - DinB_2,FGE-sulfatase SRR25158336_k127_1199361_2 1049564.TevJSym_ac01510 1.337e-36 148.0 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,1J70G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1199361_0 472759.Nhal_0581 2.989e-112 372.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1WWYX@135613|Chromatiales 135613|Chromatiales E TIGRFAM lysine 2,3-aminomutase YodO family protein - - 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM SRR25158336_k127_1199361_1 1380387.JADM01000002_gene2294 7.46e-50 184.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1XI52@135619|Oceanospirillales 135619|Oceanospirillales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C SRR25158336_k127_1199423_0 713586.KB900536_gene929 6.006e-132 443.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales 135613|Chromatiales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5,3.6.4.12 ko:K03582,ko:K16898 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C SRR25158336_k127_1199423_2 1198232.CYCME_1724 3.392e-69 244.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,460JH@72273|Thiotrichales 72273|Thiotrichales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 SRR25158336_k127_1199423_1 713586.KB900536_gene932 7.459e-130 421.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales 135613|Chromatiales L TIGRFAM Tyrosine recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SRR25158336_k127_1199423_3 1121405.dsmv_1640 1.58e-54 205.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria,2MN9G@213118|Desulfobacterales 28221|Deltaproteobacteria IQ AMP-binding enzyme - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,Acyltransferase,PP-binding SRR25158336_k127_1199423_4 1217715.F994_01959 4.738e-31 131.0 COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,1S793@1236|Gammaproteobacteria,3NJEW@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF541) Z012_10940 - - - - - - - - - - - SIMPL SRR25158336_k127_1199423_5 1249627.D779_3447 1.911e-16 79.0 COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria,1WYEG@135613|Chromatiales 135613|Chromatiales O Belongs to the thioredoxin family - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin SRR25158336_k127_119982_0 301.JNHE01000016_gene4530 9.267e-83 281.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1YDSJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_0281 THF_DHG_CYH,THF_DHG_CYH_C SRR25158336_k127_119982_2 1408445.JHXP01000007_gene376 3.79e-10 63.0 2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - SRR25158336_k127_119982_3 1122164.JHWF01000022_gene1733 2.097e-08 57.0 2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - SRR25158336_k127_119982_5 448385.sce8114 1.401e-05 47.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - 1.16.3.3,1.7.2.1 ko:K00368,ko:K22348,ko:K22349 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,DUF4396 SRR25158336_k127_119982_4 1120963.KB894491_gene1107 6.057e-06 49.0 2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_119982_1 187272.Mlg_2289 8.186e-80 274.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1WWKF@135613|Chromatiales 135613|Chromatiales O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N SRR25158336_k127_1200684_0 765912.Thimo_3262 1.047e-100 337.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales 135613|Chromatiales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos SRR25158336_k127_1200684_2 713586.KB900536_gene2631 1.431e-54 196.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1WYSF@135613|Chromatiales 135613|Chromatiales P PFAM ApaG domain protein apaG - - ko:K06195 - - - - ko00000 - - - DUF525 SRR25158336_k127_1200684_1 1049564.TevJSym_aa00390 5.038e-94 313.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1J4UT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD SRR25158336_k127_1207304_3 713586.KB900536_gene2884 3.204e-51 187.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1WX4Z@135613|Chromatiales 135613|Chromatiales S AI-2E family transporter - - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport SRR25158336_k127_1207304_4 519989.ECTPHS_00085 6.847e-26 111.0 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_1207304_0 2340.JV46_29200 1.337e-139 448.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1J4GM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate SRR25158336_k127_1207304_2 207954.MED92_02838 2.008e-96 322.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like SRR25158336_k127_1207304_1 1198232.CYCME_0382 8.217e-114 379.0 28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1211517_1 1049564.TevJSym_ao00750 3.065e-53 188.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1J52U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG1077 Actin-like ATPase involved in cell morphogenesis mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SRR25158336_k127_1211517_0 472759.Nhal_0569 4.582e-84 290.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales 135613|Chromatiales M Involved in formation and maintenance of cell shape - - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC SRR25158336_k127_1211517_2 395493.BegalDRAFT_1661 4.556e-31 127.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,461A7@72273|Thiotrichales 72273|Thiotrichales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD SRR25158336_k127_1212185_1 713586.KB900536_gene134 2.521e-90 306.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales 135613|Chromatiales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 SRR25158336_k127_1212185_0 1049564.TevJSym_ba00130 1.78e-151 489.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1J54A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188 DXPR_C,DXP_redisom_C,DXP_reductoisom SRR25158336_k127_1212185_2 1123253.AUBD01000007_gene656 7.267e-59 213.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1X5GA@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 SRR25158336_k127_1212185_3 452638.Pnec_0511 7.928e-26 107.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1K0E6@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf SRR25158336_k127_1223969_0 472759.Nhal_0500 0.0 1143.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW SRR25158336_k127_1223969_1 391615.ABSJ01000032_gene731 3.157e-90 306.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1JAGN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 SRR25158336_k127_1223969_3 713586.KB900536_gene1365 1.065e-11 71.0 COG4701@1|root,COG4701@2|Bacteria 2|Bacteria S Protein of unknown function (DUF721) Y3619 - - - - - - - - - - - DUF721 SRR25158336_k127_1223969_2 1384056.N787_09095 2.403e-74 252.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC SRR25158336_k127_1224660_1 292415.Tbd_0060 4.531e-77 261.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria 28216|Betaproteobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SRR25158336_k127_1224660_0 1249627.D779_1965 1.071e-133 434.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales 135613|Chromatiales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B SRR25158336_k127_1229063_0 713586.KB900536_gene1471 3.003e-111 377.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity - - 3.1.1.45,3.1.1.76 ko:K01061,ko:K22249 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SRR25158336_k127_1229063_1 713587.THITH_12610 1.553e-81 290.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RRJV@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Rhodanese SRR25158336_k127_1235317_1 765912.Thimo_0558 1.127e-72 250.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1WWMS@135613|Chromatiales 135613|Chromatiales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf SRR25158336_k127_1235317_0 323850.Shew_1000 9.623e-155 494.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,2Q9YG@267890|Shewanellaceae 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SRR25158336_k127_1235317_3 713586.KB900536_gene1825 8.706e-27 110.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 SRR25158336_k127_1235317_2 870187.Thini_4083 6.094e-33 130.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,46109@72273|Thiotrichales 72273|Thiotrichales S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY SRR25158336_k127_1244219_0 525897.Dbac_1188 8.908e-259 819.0 COG1524@1|root,COG3568@1|root,COG1524@2|Bacteria,COG3568@2|Bacteria,1R977@1224|Proteobacteria,43AKV@68525|delta/epsilon subdivisions,2X60Y@28221|Deltaproteobacteria 28221|Deltaproteobacteria L PFAM Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos SRR25158336_k127_1244984_2 1123368.AUIS01000005_gene447 1.497e-43 163.0 COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales 225057|Acidithiobacillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA SRR25158336_k127_1244984_0 314278.NB231_11879 1.071e-176 564.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales 135613|Chromatiales T response regulator - - - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Sigma54_activat SRR25158336_k127_1244984_1 1049564.TevJSym_au00400 1.026e-50 196.0 COG2982@1|root,COG3420@1|root,COG2982@2|Bacteria,COG3420@2|Bacteria,1QWWH@1224|Proteobacteria 1224|Proteobacteria P Beta-L-arabinofuranosidase, GH127 - - - - - - - - - - - - Beta_helix,NosD,W_rich_C SRR25158336_k127_1245692_2 402626.Rpic_2555 1.108e-12 69.0 COG2834@1|root,COG2834@2|Bacteria,1RGZJ@1224|Proteobacteria,2VTIP@28216|Betaproteobacteria,1KFIA@119060|Burkholderiaceae 28216|Betaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA SRR25158336_k127_1245692_0 396588.Tgr7_2002 9.453e-196 618.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1WVV4@135613|Chromatiales 135613|Chromatiales L AAA ATPase, central domain protein - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N SRR25158336_k127_1245692_1 1049564.TevJSym_ah00210 1.369e-36 141.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1J6UX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB SRR25158336_k127_1251931_4 572477.Alvin_2891 1.521e-17 88.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1WWEB@135613|Chromatiales 135613|Chromatiales D Part of the ABC transporter FtsEX involved in cellular division - - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX SRR25158336_k127_1251931_3 1198232.CYCME_0645 7.897e-95 316.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,4604Q@72273|Thiotrichales 72273|Thiotrichales D TIGRFAM Cell division ATP-binding protein FtsE - - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran SRR25158336_k127_1251931_1 472759.Nhal_2202 1.305e-137 447.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales 135613|Chromatiales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N SRR25158336_k127_1251931_0 1049564.TevJSym_aa00880 2.143e-176 565.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1JC0J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Insulinase (Peptidase family M16) pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR25158336_k127_1251931_2 1049564.TevJSym_aa00890 1.639e-127 420.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1J6RI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Insulinase (Peptidase family M16) - - 2.7.7.6 ko:K00960,ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C SRR25158336_k127_1256205_1 159087.Daro_3769 2.422e-78 266.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KV7X@206389|Rhodocyclales 206389|Rhodocyclales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c SRR25158336_k127_1256205_2 857087.Metme_2396 5.594e-64 227.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XF2E@135618|Methylococcales 135618|Methylococcales T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR SRR25158336_k127_1256205_0 713586.KB900536_gene3086 3.648e-83 282.0 COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,1WVYZ@135613|Chromatiales 135613|Chromatiales G TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - - - - - - - - - - HAD_2 SRR25158336_k127_1260276_0 396588.Tgr7_0764 2.004e-150 491.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1WX75@135613|Chromatiales 135613|Chromatiales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR25158336_k127_1260276_1 472759.Nhal_0486 1.2e-127 422.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1WWTC@135613|Chromatiales 135613|Chromatiales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SRR25158336_k127_1260276_2 519989.ECTPHS_01859 2.222e-80 273.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1WWBT@135613|Chromatiales 135613|Chromatiales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 SRR25158336_k127_1266500_4 396588.Tgr7_0747 4.724e-46 170.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales 135613|Chromatiales O Trypsin - - - ko:K04691 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 SRR25158336_k127_1266500_2 1049564.TevJSym_ag00170 6.752e-139 449.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1J9QP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Aminotransferase class I and II hisC GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - iECO111_1330.ECO111_2745,iSDY_1059.SDY_2220,iSSON_1240.SSON_2092 Aminotran_1_2 SRR25158336_k127_1266500_1 396588.Tgr7_0745 2.365e-205 646.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1WX79@135613|Chromatiales 135613|Chromatiales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh SRR25158336_k127_1266500_3 395493.BegalDRAFT_0722 7.04e-97 320.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,4606Y@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG - 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C SRR25158336_k127_1266500_0 1469245.JFBG01000020_gene1082 8.817e-206 646.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1WXB6@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase SRR25158336_k127_1266500_5 488538.SAR116_0672 6.259e-19 88.0 COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,4BQW5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria T Belongs to the BolA IbaG family MA20_09125 - - - - - - - - - - - BolA SRR25158336_k127_1266500_6 323261.Noc_2783 1.611e-16 83.0 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1WZDQ@135613|Chromatiales 135613|Chromatiales S NTP binding protein (Contains STAS domain) - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 SRR25158336_k127_1272246_2 555778.Hneap_0560 1.618e-43 169.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WY32@135613|Chromatiales 135613|Chromatiales P SMART Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese SRR25158336_k127_1272246_4 1163409.UUA_16633 2.783e-18 93.0 28Q4X@1|root,2ZCN0@2|Bacteria,1RA2A@1224|Proteobacteria,1S3SD@1236|Gammaproteobacteria,1X8MV@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SRR25158336_k127_1272246_0 1335757.SPICUR_05325 6.319e-112 374.0 COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1RY9Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp SRR25158336_k127_1272246_1 216591.BCAM0192 1.433e-73 257.0 28HKZ@1|root,2Z7VP@2|Bacteria,1R4QW@1224|Proteobacteria,2VMSD@28216|Betaproteobacteria,1K2QK@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3050) - - - - - - - - - - - - DUF3050 SRR25158336_k127_1272246_3 1168289.AJKI01000004_gene2957 2.666e-23 114.0 COG0823@1|root,COG1361@1|root,COG3291@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.4.24.3,4.2.2.6 ko:K01387,ko:K01730,ko:K20276 ko00040,ko02024,map00040,map02024 - R04382 RC02124,RC02427 ko00000,ko00001,ko01000,ko01002,ko02042 - - - CHU_C,PD40,PKD,Peptidase_M9 SRR25158336_k127_127772_0 572477.Alvin_1026 6.985e-235 734.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1WWAI@135613|Chromatiales 135613|Chromatiales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran SRR25158336_k127_127772_1 1049564.TevJSym_av00130 2.031e-46 172.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1J6GJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S membrane protein, required for colicin V production cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V SRR25158336_k127_127772_2 519989.ECTPHS_05380 2.663e-20 98.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1WZEE@135613|Chromatiales 135613|Chromatiales S Sporulation related domain - - - ko:K03749 - - - - ko00000 - - - SPOR SRR25158336_k127_127772_3 748247.AZKH_3105 6.263e-19 89.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,2KV9G@206389|Rhodocyclales 206389|Rhodocyclales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M SRR25158336_k127_1278732_1 765913.ThidrDRAFT_3514 1.139e-51 190.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,1SAAZ@1236|Gammaproteobacteria,1WXGU@135613|Chromatiales 135613|Chromatiales S peptidase S16, lon - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg SRR25158336_k127_1278732_2 1255043.TVNIR_3765 7.82e-36 142.0 COG1247@1|root,COG1247@2|Bacteria,1NZ6C@1224|Proteobacteria,1SPXX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 SRR25158336_k127_1278732_0 1027273.GZ77_18240 1.094e-73 255.0 COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,1S615@1236|Gammaproteobacteria,1XK04@135619|Oceanospirillales 135619|Oceanospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short SRR25158336_k127_1278732_4 78245.Xaut_0975 2.081e-17 90.0 COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2U7KA@28211|Alphaproteobacteria 28211|Alphaproteobacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Copper-bind,Cupredoxin_1 SRR25158336_k127_1278732_3 1122599.AUGR01000010_gene1038 5.323e-28 116.0 COG3011@1|root,COG3011@2|Bacteria,1PV30@1224|Proteobacteria,1SCCX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 SRR25158336_k127_1279648_1 1123400.KB904747_gene582 2.173e-131 421.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,460AX@72273|Thiotrichales 72273|Thiotrichales E Serine dehydratase beta chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta SRR25158336_k127_1279648_0 1042375.AFPL01000036_gene2994 9.629e-160 509.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae 1236|Gammaproteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroF GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 DAHP_synth_1 SRR25158336_k127_1281357_2 519989.ECTPHS_00315 1.502e-23 102.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1WYWG@135613|Chromatiales 135613|Chromatiales H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK SRR25158336_k127_1281357_1 396588.Tgr7_0880 7.284e-83 280.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1X2ET@135613|Chromatiales 135613|Chromatiales F Deoxynucleoside kinase - - - - - - - - - - - - dNK SRR25158336_k127_1281357_0 1123401.JHYQ01000002_gene2780 1.024e-88 300.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,4609A@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf SRR25158336_k127_1286186_2 631362.Thi970DRAFT_04763 1.303e-179 566.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1X0ZR@135613|Chromatiales 135613|Chromatiales O HflC and HflK could regulate a protease - - - - - - - - - - - - Band_7 SRR25158336_k127_1286186_1 331869.BAL199_28440 2.434e-183 578.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,4BP7N@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N SRR25158336_k127_1286186_3 768671.ThimaDRAFT_2390 2.993e-16 83.0 COG2920@1|root,COG2920@2|Bacteria,1N6BU@1224|Proteobacteria,1S6FJ@1236|Gammaproteobacteria,1WYPC@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC SRR25158336_k127_1286186_0 153948.NAL212_0278 0.0 2924.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,371PE@32003|Nitrosomonadales 28216|Betaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain - - - - - - - - - - - - Glyco_hydro_36,Glyco_transf_36,Glycoamylase SRR25158336_k127_128792_1 1166948.JPZL01000004_gene17 2.909e-85 289.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XII3@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 SRR25158336_k127_128792_0 582744.Msip34_0660 9.678e-122 399.0 COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria,2KKKC@206350|Nitrosomonadales 206350|Nitrosomonadales E Belongs to the peptidase M17 family - - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 SRR25158336_k127_1295168_0 1049564.TevJSym_ca00050 1.408e-237 749.0 COG1033@1|root,COG2834@1|root,COG1033@2|Bacteria,COG2834@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1J96Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M MMPL family VP1286 - - ko:K07003 - - - - ko00000 - - - MMPL SRR25158336_k127_1298974_1 247634.GPB2148_2212 3.678e-34 136.0 COG0438@1|root,COG0438@2|Bacteria,1MZH2@1224|Proteobacteria,1S9AM@1236|Gammaproteobacteria,1JB0Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Glycosyl transferase, group 1 - - 2.4.1.346 ko:K13668 - - R11703,R11704 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SRR25158336_k127_1298974_0 314278.NB231_05511 1.301e-158 509.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N SRR25158336_k127_1300260_1 870187.Thini_4174 1.328e-11 65.0 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria,460GK@72273|Thiotrichales 72273|Thiotrichales L 3'-5' exonuclease - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 SRR25158336_k127_1300260_0 519989.ECTPHS_08423 1.936e-158 511.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1WWDA@135613|Chromatiales 135613|Chromatiales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr SRR25158336_k127_1301850_2 1049564.TevJSym_as00260 2.195e-14 77.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1J6C8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 SRR25158336_k127_1301850_0 243233.MCA1458 2.976e-135 437.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XE38@135618|Methylococcales 135618|Methylococcales T PFAM PhoH-like protein - - - ko:K06217 - - - - ko00000 - - - PhoH SRR25158336_k127_1301850_1 713586.KB900536_gene1139 3.771e-69 237.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SRR25158336_k127_1307290_1 396588.Tgr7_2171 1.129e-78 267.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1WWCR@135613|Chromatiales 135613|Chromatiales K response regulator receiver - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg SRR25158336_k127_1307290_2 1049564.TevJSym_ax00390 2e-58 206.0 COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1JBZG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese SRR25158336_k127_1307290_3 713586.KB900536_gene999 4.441e-29 119.0 COG2932@1|root,COG2932@2|Bacteria,1NBZE@1224|Proteobacteria,1S6MQ@1236|Gammaproteobacteria,1WYPT@135613|Chromatiales 135613|Chromatiales K Peptidase S24-like - - - - - - - - - - - - Peptidase_S24 SRR25158336_k127_1307290_0 1266908.AQPB01000026_gene2710 3.813e-178 562.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1WWHP@135613|Chromatiales 135613|Chromatiales M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd SRR25158336_k127_1307290_4 1121015.N789_03430 3.708e-17 81.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1X3V0@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family vipA - - ko:K02474 ko00520,map00520 - R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SRR25158336_k127_1307479_4 1121015.N789_10100 2.213e-06 55.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X69F@135614|Xanthomonadales 135614|Xanthomonadales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE SRR25158336_k127_1307479_0 396588.Tgr7_2905 2.605e-133 433.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1WVY1@135613|Chromatiales 135613|Chromatiales HJ Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N SRR25158336_k127_1307479_1 314278.NB231_13326 6.415e-56 199.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02657 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg SRR25158336_k127_1307479_2 1269813.ATUL01000041_gene2767 2.281e-46 169.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYZY@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg SRR25158336_k127_1307479_3 1123020.AUIE01000025_gene4780 4.197e-35 141.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1YCQV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Two component signalling adaptor domain pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW SRR25158336_k127_1314597_0 998674.ATTE01000001_gene2472 1.631e-105 349.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,4602A@72273|Thiotrichales 72273|Thiotrichales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SRR25158336_k127_1314597_2 314345.SPV1_08076 8.549e-28 114.0 2E4RC@1|root,32ZJW@2|Bacteria,1N8RU@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1314597_1 1535422.ND16A_1858 6.279e-89 302.0 COG0500@1|root,COG2226@2|Bacteria,1PDVU@1224|Proteobacteria,1RXQY@1236|Gammaproteobacteria,2Q853@267889|Colwelliaceae 1236|Gammaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - - SRR25158336_k127_1315344_1 1163617.SCD_n01123 1.432e-55 199.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria 28216|Betaproteobacteria S Haloacid dehalogenase-like hydrolase - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 SRR25158336_k127_1315344_0 713586.KB900536_gene1719 1.852e-61 215.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC SRR25158336_k127_1315344_2 1049564.TevJSym_av00350 9.611e-08 60.0 2DNRG@1|root,32YSH@2|Bacteria,1QFRE@1224|Proteobacteria,1TCNT@1236|Gammaproteobacteria,1J7AH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Type II secretion system (T2SS), protein N - - - - - - - - - - - - T2SSN SRR25158336_k127_1315681_0 1123518.ARWI01000001_gene995 5.048e-194 614.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,45ZTY@72273|Thiotrichales 72273|Thiotrichales HJ Glutathione synthase Ribosomal protein S6 modification enzyme - - - - - - - - - - - - RLAN,RimK SRR25158336_k127_1315681_1 1123514.KB905899_gene1994 4.413e-94 315.0 COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,1S0KZ@1236|Gammaproteobacteria,463AF@72273|Thiotrichales 72273|Thiotrichales S Uncharacterised ACR, YagE family COG1723 - - - - - - - - - - - - DUF155 SRR25158336_k127_1316453_4 1121374.KB891585_gene1924 8.657e-62 214.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C SRR25158336_k127_1316453_1 243233.MCA1465 2.679e-104 345.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XEDU@135618|Methylococcales 135618|Methylococcales U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 SRR25158336_k127_1316453_6 523791.Kkor_0754 3.047e-19 92.0 COG4969@1|root,COG4969@2|Bacteria 2|Bacteria NU cell adhesion - - - - - - - - - - - - DUF4845 SRR25158336_k127_1316453_3 1122599.AUGR01000023_gene4133 2.02e-69 241.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XHKG@135619|Oceanospirillales 135619|Oceanospirillales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm SRR25158336_k127_1316453_0 351348.Maqu_2244 2.284e-114 376.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,464IK@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 SRR25158336_k127_1316453_5 105559.Nwat_2316 3.424e-55 203.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales 135613|Chromatiales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N SRR25158336_k127_1316453_2 105559.Nwat_2315 2.085e-103 340.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales 135613|Chromatiales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ SRR25158336_k127_1316453_7 1046724.KB889827_gene2604 2.278e-05 48.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464QT@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase barA GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 ko:K07678 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg SRR25158336_k127_1321735_2 2340.JV46_16440 4.978e-40 156.0 COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,1T211@1236|Gammaproteobacteria,1JB6B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 SRR25158336_k127_1321735_1 1182590.BN5_02963 1.751e-76 260.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1YD6T@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Nudix N-terminal - - - - - - - - - - - - NUDIX,Nudix_N_2 SRR25158336_k127_1321735_3 1340493.JNIF01000004_gene704 4.93e-25 111.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC SRR25158336_k127_1321735_0 323261.Noc_2131 9.638e-79 273.0 COG1985@1|root,COG1985@2|Bacteria,1RDMT@1224|Proteobacteria,1S4SQ@1236|Gammaproteobacteria,1X05Z@135613|Chromatiales 135613|Chromatiales H RibD C-terminal domain - - - - - - - - - - - - RibD_C SRR25158336_k127_1321849_5 519989.ECTPHS_05811 1.304e-70 246.0 COG1120@1|root,COG1120@2|Bacteria,1MWPV@1224|Proteobacteria,1T1UT@1236|Gammaproteobacteria,1WYFV@135613|Chromatiales 135613|Chromatiales HP PFAM ABC transporter - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran SRR25158336_k127_1321849_1 1177154.Y5S_03203 2.876e-106 355.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XIU2@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD SRR25158336_k127_1321849_2 686340.Metal_1485 2.673e-88 305.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XEB3@135618|Methylococcales 135618|Methylococcales E subfamily IB - - - - - - - - - - - - HAD SRR25158336_k127_1321849_3 187272.Mlg_0427 9.982e-76 256.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales 135613|Chromatiales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX SRR25158336_k127_1321849_0 1049564.TevJSym_bp00060 1.339e-273 861.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Belongs to the PEP-utilizing enzyme family ptsP GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 ko:K08483,ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C SRR25158336_k127_1321849_4 754476.Q7A_1036 7.034e-75 255.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,463KN@72273|Thiotrichales 72273|Thiotrichales S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 SRR25158336_k127_1321849_7 673860.AciM339_0907 3.555e-11 76.0 COG1361@1|root,arCOG02527@1|root,arCOG02089@2157|Archaea,arCOG02527@2157|Archaea,2Y6ZW@28890|Euryarchaeota,3F314@33867|unclassified Euryarchaeota 28890|Euryarchaeota M COG1361 S-layer domain - - - - - - - - - - - - - SRR25158336_k127_1321849_6 1168065.DOK_14964 6.631e-12 68.0 COG3182@1|root,COG3182@2|Bacteria,1QVX4@1224|Proteobacteria,1T2MJ@1236|Gammaproteobacteria,1J7B0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM SRR25158336_k127_1324900_1 330214.NIDE0819 5.443e-10 70.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety omp-1X - - ko:K12976,ko:K22110 - - - - ko00000,ko01000,ko01005,ko02000 1.B.35.1,1.B.35.2 - - DUF2490,OMP_b-brl,Surface_Ag_2 SRR25158336_k127_1324900_0 1123355.JHYO01000034_gene563 1.074e-117 383.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,36XHA@31993|Methylocystaceae 28211|Alphaproteobacteria P AcrB/AcrD/AcrF family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran SRR25158336_k127_1326567_0 105559.Nwat_0988 3.875e-148 479.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SRR25158336_k127_1326567_3 743721.Psesu_2980 6.778e-62 222.0 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,1T1K8@1236|Gammaproteobacteria,1X3DZ@135614|Xanthomonadales 135614|Xanthomonadales I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 SRR25158336_k127_1326567_1 768671.ThimaDRAFT_3356 1.89e-108 358.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales 135613|Chromatiales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 SRR25158336_k127_1326567_2 754477.Q7C_1313 3.024e-66 231.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,460T0@72273|Thiotrichales 72273|Thiotrichales H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 SRR25158336_k127_1338788_1 765910.MARPU_11120 8.526e-43 167.0 COG3026@1|root,COG3026@2|Bacteria,1R1SQ@1224|Proteobacteria,1T596@1236|Gammaproteobacteria,1X2UZ@135613|Chromatiales 135613|Chromatiales T antisigma factor binding - - - - - - - - - - - - - SRR25158336_k127_1338788_0 156889.Mmc1_3256 5.32e-59 211.0 COG1192@1|root,COG1192@2|Bacteria 2|Bacteria D plasmid maintenance - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA SRR25158336_k127_1345422_0 2340.JV46_28240 3.075e-168 545.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase SRR25158336_k127_1345940_2 572477.Alvin_1653 2.687e-83 277.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales 135613|Chromatiales C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 SRR25158336_k127_1345940_4 396588.Tgr7_1482 2.673e-17 85.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales 135613|Chromatiales S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 SRR25158336_k127_1345940_5 396588.Tgr7_1483 2.973e-06 55.0 COG0694@1|root,COG0694@2|Bacteria,1NHWB@1224|Proteobacteria,1SSTK@1236|Gammaproteobacteria 1236|Gammaproteobacteria O NifU-like domain - - - ko:K19168 - - - - ko00000,ko02048 - - - NifU SRR25158336_k127_1345940_0 472759.Nhal_3055 2.244e-181 580.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1X2HE@135613|Chromatiales 135613|Chromatiales E PFAM Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SRR25158336_k127_1345940_3 472759.Nhal_2855 2.437e-62 218.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,1X25T@135613|Chromatiales 135613|Chromatiales S PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD SRR25158336_k127_1345940_1 1232683.ADIMK_0084 7.759e-85 286.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C SRR25158336_k127_1348076_1 247633.GP2143_01355 3.048e-86 289.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1J57N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SRR25158336_k127_1348076_0 2340.JV46_16660 5.995e-139 458.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1J4FQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EGP major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr SRR25158336_k127_1348076_2 2340.JV46_16650 2.442e-65 226.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J6EM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB SRR25158336_k127_1348076_3 1266914.ATUK01000015_gene967 1.753e-22 99.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S6RN@1236|Gammaproteobacteria,1X27A@135613|Chromatiales 135613|Chromatiales K MraZ protein, putative antitoxin-like mraZ - - ko:K03925 - - - - ko00000 - - - MraZ SRR25158336_k127_1348567_7 765912.Thimo_0612 3.744e-10 61.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 SRR25158336_k127_1348567_3 1395571.TMS3_0109970 3.943e-78 271.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 SRR25158336_k127_1348567_1 1282876.BAOK01000001_gene1673 2.006e-98 335.0 COG4313@1|root,COG4313@2|Bacteria,1MXNW@1224|Proteobacteria,2TV0V@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl,Phenol_MetA_deg SRR25158336_k127_1348567_0 338969.Rfer_0396 9.415e-189 593.0 COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria,4AGJH@80864|Comamonadaceae 28216|Betaproteobacteria C Radical SAM superfamily pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM SRR25158336_k127_1348567_4 292415.Tbd_1586 3.833e-61 216.0 COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales 119069|Hydrogenophilales S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo SRR25158336_k127_1348567_2 338969.Rfer_0398 6.365e-98 328.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,4AGRN@80864|Comamonadaceae 28216|Betaproteobacteria S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo SRR25158336_k127_1348567_5 1049564.TevJSym_ag00030 1.344e-60 213.0 COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1J689@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S phosphatase homologous to the C-terminal domain of histone macroH2A1 ymdB GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - - - - - - - - - - Macro SRR25158336_k127_1348567_6 631362.Thi970DRAFT_04049 1.079e-13 76.0 COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,1T2FP@1236|Gammaproteobacteria,1WWXW@135613|Chromatiales 135613|Chromatiales C PFAM 2Fe-2S iron-sulfur cluster binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2 SRR25158336_k127_1349768_7 1049564.TevJSym_bh00090 4.258e-09 59.0 COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,1RSFQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Tetratricopeptide - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_16 SRR25158336_k127_1349768_4 1049564.TevJSym_bh00080 3.401e-74 271.0 28JIE@1|root,2Z9BR@2|Bacteria,1R952@1224|Proteobacteria,1RRHU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Oxygen tolerance - - - - - - - - - - - - BatD SRR25158336_k127_1349768_0 2340.JV46_27740 1.048e-182 580.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,1RSMW@1236|Gammaproteobacteria,1JB8I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp SRR25158336_k127_1349768_1 686340.Metal_2823 2.026e-106 348.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XETJ@135618|Methylococcales 135618|Methylococcales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC SRR25158336_k127_1349768_2 396588.Tgr7_2226 9.535e-99 329.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales 135613|Chromatiales O Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM SRR25158336_k127_1349768_5 396588.Tgr7_2227 5.155e-49 185.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales 135613|Chromatiales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri,YfiO SRR25158336_k127_1349768_6 1286106.MPL1_01259 6.281e-44 166.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,460Y2@72273|Thiotrichales 72273|Thiotrichales M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA SRR25158336_k127_1349768_3 1283300.ATXB01000002_gene3020 3.922e-90 301.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XEH5@135618|Methylococcales 135618|Methylococcales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N SRR25158336_k127_1349952_1 472759.Nhal_1157 3.032e-72 246.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales 135613|Chromatiales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 SRR25158336_k127_1349952_2 637389.Acaty_c2047 9.978e-31 123.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,2ND4V@225057|Acidithiobacillales 225057|Acidithiobacillales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 SRR25158336_k127_1349952_0 472759.Nhal_1712 1.858e-157 502.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WXNN@135613|Chromatiales 1236|Gammaproteobacteria F PFAM glycosyl transferase family 35 - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase SRR25158336_k127_1362392_1 1123392.AQWL01000001_gene1406 4.024e-13 69.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria 28216|Betaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI SRR25158336_k127_1362392_0 713586.KB900536_gene2043 4.968e-126 413.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,1WWYY@135613|Chromatiales 135613|Chromatiales S FIST N domain - - - - - - - - - - - - FIST,FIST_C SRR25158336_k127_1362968_2 1552758.NC00_18530 2.132e-08 58.0 COG2353@1|root,COG2353@2|Bacteria,1RHEW@1224|Proteobacteria,1S6XG@1236|Gammaproteobacteria,1X60U@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI SRR25158336_k127_1362968_1 1283283.ATXA01000003_gene1704 1.565e-11 73.0 COG0639@1|root,COG0639@2|Bacteria 2|Bacteria T phosphoprotein phosphatase activity - - - - - - - - - - - - Metallophos_2 SRR25158336_k127_1362968_0 670307.HYPDE_33213 5.898e-65 229.0 COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria 1224|Proteobacteria S Lipase maturation factor - - - - - - - - - - - - DUF393,LMF1 SRR25158336_k127_1363665_0 572477.Alvin_1774 3.047e-200 627.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT SRR25158336_k127_1363665_5 472759.Nhal_2810 1.981e-66 229.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1WX91@135613|Chromatiales 135613|Chromatiales K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone SRR25158336_k127_1363665_2 713586.KB900536_gene501 2.322e-134 439.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales 135613|Chromatiales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 SRR25158336_k127_1363665_4 1123401.JHYQ01000003_gene2144 2.57e-88 296.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,460GU@72273|Thiotrichales 72273|Thiotrichales H riboflavin synthase, alpha ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding SRR25158336_k127_1363665_1 187272.Mlg_0377 2.307e-149 480.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 SRR25158336_k127_1363665_6 765912.Thimo_0211 6.601e-65 227.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1WX65@135613|Chromatiales 135613|Chromatiales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase SRR25158336_k127_1363665_8 1123253.AUBD01000009_gene2285 1.284e-39 152.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1X6GZ@135614|Xanthomonadales 135614|Xanthomonadales K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB SRR25158336_k127_1363665_3 105559.Nwat_2306 4.174e-95 321.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1WW48@135613|Chromatiales 135613|Chromatiales H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SRR25158336_k127_1363665_7 2340.JV46_20480 5.379e-60 212.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1J67X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA SRR25158336_k127_1363665_9 329726.AM1_2994 5.61e-20 94.0 COG0664@1|root,COG0664@2|Bacteria,1G9GW@1117|Cyanobacteria 1117|Cyanobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding SRR25158336_k127_1363730_4 1163617.SCD_n01765 3.963e-07 57.0 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - 4HB_MCP_1,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_7,PAS_8,PAS_9,Response_reg SRR25158336_k127_1363730_2 1337936.IJ00_07980 1.123e-65 231.0 COG0491@1|root,COG0491@2|Bacteria,1G0CZ@1117|Cyanobacteria,1HMAK@1161|Nostocales 1117|Cyanobacteria S Hydrolase - - - - - - - - - - - - Lactamase_B,NAD_binding_9 SRR25158336_k127_1363730_0 344747.PM8797T_12503 7.66e-286 885.0 COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes 203682|Planctomycetes H Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD SRR25158336_k127_1363730_3 754477.Q7C_1748 2.117e-53 196.0 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,463VV@72273|Thiotrichales 72273|Thiotrichales T SH3 domain - - - ko:K07184 - - - - ko00000 - - - SH3_3 SRR25158336_k127_1363730_1 2340.JV46_07870 6.185e-68 234.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1J61Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG3023 Negative regulator of beta-lactamase expression ampD GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560 Amidase_2 SRR25158336_k127_1365615_3 1049564.TevJSym_aa00010 3.136e-50 179.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1J66Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 SRR25158336_k127_1365615_1 396588.Tgr7_2324 2.877e-98 324.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 SRR25158336_k127_1365615_2 768066.HELO_1237 4.161e-78 265.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 SRR25158336_k127_1365615_4 557598.LHK_00255 4.586e-32 127.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,2KRGC@206351|Neisseriales 206351|Neisseriales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 SRR25158336_k127_1365615_0 1278309.KB907106_gene1316 1.261e-138 444.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XHKX@135619|Oceanospirillales 135619|Oceanospirillales J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB - - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C SRR25158336_k127_1369398_8 1158762.KB898039_gene1707 1.643e-05 49.0 COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1WYTZ@135613|Chromatiales 135613|Chromatiales KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg SRR25158336_k127_1369398_7 631362.Thi970DRAFT_02259 1.507e-39 151.0 COG0790@1|root,COG0790@2|Bacteria,1N293@1224|Proteobacteria,1SBGP@1236|Gammaproteobacteria,1WYX5@135613|Chromatiales 135613|Chromatiales S Sel1-like repeats. - - - - - - - - - - - - Sel1 SRR25158336_k127_1369398_3 713586.KB900536_gene1793 1.244e-102 341.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1WXE3@135613|Chromatiales 135613|Chromatiales G PFAM Fructosamine - - - - - - - - - - - - Fructosamin_kin SRR25158336_k127_1369398_5 84531.JMTZ01000126_gene4289 1.318e-87 298.0 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1X448@135614|Xanthomonadales 135614|Xanthomonadales L Exodeoxyribonuclease IX exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N SRR25158336_k127_1369398_4 396588.Tgr7_0267 3.267e-98 323.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales 135613|Chromatiales L PFAM HNH endonuclease - - - - - - - - - - - - HNH_5 SRR25158336_k127_1369398_0 713586.KB900536_gene91 4.163e-300 931.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales 135613|Chromatiales C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2 SRR25158336_k127_1369398_2 713586.KB900536_gene2412 3.635e-143 464.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1WWTF@135613|Chromatiales 135613|Chromatiales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM SRR25158336_k127_1369398_6 666685.R2APBS1_0932 7.021e-43 162.0 COG3288@1|root,COG3288@2|Bacteria,1N0TD@1224|Proteobacteria,1SA8D@1236|Gammaproteobacteria,1XCEC@135614|Xanthomonadales 135614|Xanthomonadales C 4TM region of pyridine nucleotide transhydrogenase, mitoch - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM SRR25158336_k127_1369398_1 713586.KB900536_gene2410 1.88e-196 622.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB SRR25158336_k127_1373419_0 765912.Thimo_1704 2.876e-175 570.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales 135613|Chromatiales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE SRR25158336_k127_1373419_1 472759.Nhal_2016 3.797e-169 547.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX16@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SRR25158336_k127_1373419_2 880073.Calab_2000 1.95e-94 319.0 COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria 2|Bacteria GM NAD(P)H-binding wbpP - 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SRR25158336_k127_1376594_7 1255043.TVNIR_2167 1.052e-22 101.0 2ECSY@1|root,336QI@2|Bacteria,1N9AZ@1224|Proteobacteria,1S9XM@1236|Gammaproteobacteria,1WYWD@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_1376594_5 1049564.TevJSym_as00540 1.005e-28 123.0 29QAQ@1|root,30B9W@2|Bacteria,1RGQ5@1224|Proteobacteria,1S5E4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1376594_1 395493.BegalDRAFT_0112 6.813e-102 342.0 COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,463Q9@72273|Thiotrichales 72273|Thiotrichales S PFAM Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SRR25158336_k127_1376594_0 472759.Nhal_2510 1.475e-125 410.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1WX3U@135613|Chromatiales 135613|Chromatiales C PFAM Alcohol dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N SRR25158336_k127_1376594_2 335283.Neut_1064 2.04e-64 225.0 COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2VTIJ@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM TspO MBR family protein - - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR SRR25158336_k127_1376594_4 1198232.CYCME_0186 2.929e-44 167.0 COG3663@1|root,COG3663@2|Bacteria,1RAVZ@1224|Proteobacteria,1S2GN@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells mug - 3.2.2.28 ko:K03649 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG SRR25158336_k127_1376594_3 76114.ebA6535 2.999e-48 177.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,2VRXM@28216|Betaproteobacteria,2KYQK@206389|Rhodocyclales 206389|Rhodocyclales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit SRR25158336_k127_1376594_9 661367.LLO_0471 1.078e-11 66.0 2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - SRR25158336_k127_1376594_10 441769.ABFU01000130_gene2342 7.335e-08 54.0 2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - SRR25158336_k127_1376594_8 1286106.MPL1_06014 7.709e-16 77.0 COG0050@1|root,COG0050@2|Bacteria 2|Bacteria J translation elongation factor activity tuf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 SRR25158336_k127_1378480_5 666685.R2APBS1_1826 1.258e-28 117.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1X3M2@135614|Xanthomonadales 135614|Xanthomonadales L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N SRR25158336_k127_1378480_1 1198232.CYCME_1000 7.093e-60 210.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,460PC@72273|Thiotrichales 72273|Thiotrichales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR SRR25158336_k127_1378480_4 223283.PSPTO_4509 5.312e-32 130.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1Z591@136849|Pseudomonas syringae group 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA SRR25158336_k127_1378480_3 522306.CAP2UW1_1936 4.406e-33 132.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,1KQ51@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Belongs to the UPF0125 (RnfH) family rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH SRR25158336_k127_1378480_2 1231391.AMZF01000014_gene2332 8.37e-41 154.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,3T3I7@506|Alcaligenaceae 28216|Betaproteobacteria I oligoketide cyclase lipid transport protein ratA - - - - - - - - - - - Polyketide_cyc SRR25158336_k127_1378480_0 1249627.D779_0297 1.617e-115 379.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF SRR25158336_k127_1382351_0 1283300.ATXB01000001_gene518 1.914e-262 820.0 COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,1XGVI@135618|Methylococcales 135618|Methylococcales G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - - SRR25158336_k127_1382351_1 225937.HP15_2673 2.195e-26 109.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,1S5SK@1236|Gammaproteobacteria,468K2@72275|Alteromonadaceae 1236|Gammaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SRR25158336_k127_1383106_0 713586.KB900536_gene1109 2.974e-95 330.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_3,Protoglobin,Response_reg SRR25158336_k127_1384381_0 768671.ThimaDRAFT_0602 0.0 1175.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW08@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran SRR25158336_k127_138923_1 1123276.KB893246_gene571 1.01e-07 61.0 COG1216@1|root,COG1216@2|Bacteria,4NIKM@976|Bacteroidetes,47M8F@768503|Cytophagia 976|Bacteroidetes S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SRR25158336_k127_138923_0 1123401.JHYQ01000010_gene2451 1.822e-92 309.0 COG2227@1|root,COG2227@2|Bacteria,1NJV4@1224|Proteobacteria,1T1GP@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 SRR25158336_k127_1393723_1 1117647.M5M_12500 1.664e-98 330.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1J52T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc SRR25158336_k127_1393723_4 472759.Nhal_3953 2.622e-08 60.0 2DSZ4@1|root,33I02@2|Bacteria,1NGMX@1224|Proteobacteria,1SGFG@1236|Gammaproteobacteria,1X20S@135613|Chromatiales 135613|Chromatiales S ATP synthase I chain - - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I SRR25158336_k127_1393723_0 1123393.KB891332_gene2796 1.285e-129 422.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales 119069|Hydrogenophilales C ATP synthase A chain - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A SRR25158336_k127_1393723_3 1049564.TevJSym_aq00410 2.064e-35 135.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1J6WA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C SRR25158336_k127_1393723_2 1123393.KB891332_gene2798 4.615e-37 142.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,1KS17@119069|Hydrogenophilales 119069|Hydrogenophilales C ATP synthase B/B' CF(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B SRR25158336_k127_1395230_2 1049564.TevJSym_ax00280 1.04e-57 203.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1J4QH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Permease perM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport SRR25158336_k127_1395230_1 1122134.KB893651_gene2330 8.327e-66 236.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XJJA@135619|Oceanospirillales 135619|Oceanospirillales O Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SRR25158336_k127_1395230_0 1049564.TevJSym_ax00210 2.167e-66 231.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1JBWT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E ACT domain gcvR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT,ACT_6 SRR25158336_k127_1397860_1 1249627.D779_1739 4.328e-52 186.0 COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S765@1236|Gammaproteobacteria,1WYIN@135613|Chromatiales 135613|Chromatiales C PFAM Ribulose bisphosphate carboxylase, small chain - - 4.1.1.39 ko:K01602 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_small SRR25158336_k127_1397860_0 751994.AGIG01000034_gene412 5.002e-298 916.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1J7UP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Ribulose bisphosphate carboxylase large chain, catalytic domain cbbL - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N SRR25158336_k127_1397860_2 1158146.KB907125_gene2264 3.071e-20 91.0 COG1051@1|root,COG1051@2|Bacteria,1RC3I@1224|Proteobacteria,1S34Y@1236|Gammaproteobacteria,1WY35@135613|Chromatiales 135613|Chromatiales F NUDIX domain - - - - - - - - - - - - NUDIX SRR25158336_k127_1400407_0 472759.Nhal_0217 8.381e-81 279.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales 135613|Chromatiales S TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB SRR25158336_k127_1400407_1 396588.Tgr7_2935 7.343e-32 130.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SARP@1236|Gammaproteobacteria 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease SRR25158336_k127_1400407_2 1266914.ATUK01000001_gene790 4.67e-09 66.0 2ERTY@1|root,33JD5@2|Bacteria,1NIJV@1224|Proteobacteria,1SIGE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4412 SRR25158336_k127_1417876_0 713586.KB900536_gene3056 1.801e-88 296.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M SRR25158336_k127_1417876_1 396588.Tgr7_1000 1.254e-32 129.0 2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,1SDWS@1236|Gammaproteobacteria,1X22K@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2818) - - - - - - - - - - - - DUF2818 SRR25158336_k127_1417876_2 1236542.BALM01000001_gene233 2.048e-29 122.0 COG3409@1|root,COG3409@2|Bacteria,1N3E4@1224|Proteobacteria,1RZ2A@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 SRR25158336_k127_1418331_1 1198232.CYCME_0292 9.241e-93 307.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,460VE@72273|Thiotrichales 72273|Thiotrichales S Sodium:solute symporter family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF SRR25158336_k127_1418331_4 1201293.AKXQ01000015_gene1383 2.67e-31 128.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - DUF4212 SRR25158336_k127_1418331_0 1121937.AUHJ01000005_gene2321 7.732e-168 543.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,464IG@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 SRR25158336_k127_1418331_3 396588.Tgr7_1074 1.351e-45 166.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1WYVE@135613|Chromatiales 135613|Chromatiales S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd SRR25158336_k127_1418331_2 187272.Mlg_1508 3.862e-85 288.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1WY1A@135613|Chromatiales 135613|Chromatiales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 SRR25158336_k127_1418331_5 187272.Mlg_1507 3.346e-30 121.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales 135613|Chromatiales FG PFAM Histidine triad (HIT) protein - - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT SRR25158336_k127_1419991_0 237368.SCABRO_02538 7.652e-62 220.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2IXNK@203682|Planctomycetes 203682|Planctomycetes S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH SRR25158336_k127_1419991_2 498211.CJA_0059 2.008e-14 79.0 2BWJV@1|root,32U7J@2|Bacteria,1N47S@1224|Proteobacteria,1S8XJ@1236|Gammaproteobacteria,1FI8Q@10|Cellvibrio 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1419991_1 207954.MED92_02279 1.316e-36 139.0 COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XJZ5@135619|Oceanospirillales 135619|Oceanospirillales T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS SRR25158336_k127_1423099_1 1265313.HRUBRA_02129 2.484e-46 174.0 COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,1SIHP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 SRR25158336_k127_1423099_0 1168065.DOK_19075 6.72e-59 213.0 COG1914@1|root,COG1914@2|Bacteria 2|Bacteria P metal ion transmembrane transporter activity mntH - - - - - - - - - - - Nramp SRR25158336_k127_1431476_0 713586.KB900536_gene2349 4.986e-104 340.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1WY8J@135613|Chromatiales 135613|Chromatiales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth SRR25158336_k127_1431476_2 1415754.JQMK01000013_gene36 2.318e-61 214.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,4679A@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH SRR25158336_k127_1431476_3 2340.JV46_18610 2.173e-41 155.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1J6FV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH SRR25158336_k127_1431476_6 1049564.TevJSym_bh00280 3.764e-18 85.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1J788@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 SRR25158336_k127_1431476_5 765913.ThidrDRAFT_2327 5.702e-22 99.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1WZ88@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 SRR25158336_k127_1431476_1 2340.JV46_18640 5.703e-100 334.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1J4ZF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC SRR25158336_k127_1431476_4 395961.Cyan7425_3848 1.007e-38 150.0 COG5001@1|root,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,3KG35@43988|Cyanothece 1117|Cyanobacteria T GGDEF domain containing protein - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS_3,PAS_4,PAS_9 SRR25158336_k127_1431948_0 1049564.TevJSym_aa00670 0.0 1300.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1J4ES@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS SRR25158336_k127_1434787_0 765914.ThisiDRAFT_0354 1.362e-134 436.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis SRR25158336_k127_1434787_1 765912.Thimo_2384 5.055e-25 104.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1WZ7D@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p SRR25158336_k127_1434787_2 1384054.N790_01575 3.068e-21 99.0 COG1399@1|root,COG1399@2|Bacteria,1PSXM@1224|Proteobacteria,1SWVC@1236|Gammaproteobacteria,1X6K9@135614|Xanthomonadales 135614|Xanthomonadales S ACR protein - - - ko:K07040 - - - - ko00000 - - - DUF177 SRR25158336_k127_1436550_4 396588.Tgr7_0902 8.791e-36 137.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His SRR25158336_k127_1436550_5 1198232.CYCME_0911 1.62e-13 73.0 COG3242@1|root,COG3242@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2065) yjeT - - ko:K09937 - - - - ko00000 - - - DUF2065 SRR25158336_k127_1436550_2 90813.JQMT01000001_gene1095 6.61e-90 304.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,460B4@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 SRR25158336_k127_1436550_1 1249627.D779_0211 6.844e-106 355.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales 135613|Chromatiales O HflC and HflK could encode or regulate a protease - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N SRR25158336_k127_1436550_0 713586.KB900536_gene2959 3.161e-163 524.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1WVYW@135613|Chromatiales 135613|Chromatiales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 SRR25158336_k127_1436550_3 2340.JV46_15170 8.839e-38 142.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1JAVT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq SRR25158336_k127_1436563_0 768671.ThimaDRAFT_4175 1.157e-181 578.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales 135613|Chromatiales O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C SRR25158336_k127_1436563_1 768671.ThimaDRAFT_4176 1.591e-22 102.0 COG0589@1|root,COG0589@2|Bacteria,1N8R6@1224|Proteobacteria,1SFRC@1236|Gammaproteobacteria,1X2PS@135613|Chromatiales 135613|Chromatiales T Universal stress protein family - - - - - - - - - - - - - SRR25158336_k127_1437828_1 751994.AGIG01000035_gene357 1.023e-269 838.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7VQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F 5'-nucleotidase, C-terminal domain soxB - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C SRR25158336_k127_1437828_2 751994.AGIG01000035_gene356 2.931e-124 409.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1JA2H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 SRR25158336_k127_1437828_0 1278307.KB906976_gene1564 3.233e-312 977.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Exporters of the RND superfamily - - - ko:K07003 - - - - ko00000 - - - MMPL SRR25158336_k127_1437828_3 1288826.MSNKSG1_07623 4.143e-43 162.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,465VZ@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR25158336_k127_1449509_2 1178482.BJB45_04650 6.691e-12 65.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XI0Q@135619|Oceanospirillales 135619|Oceanospirillales P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N SRR25158336_k127_1449509_3 743720.Psefu_1276 1.156e-11 69.0 2FINC@1|root,34AE7@2|Bacteria,1P2MB@1224|Proteobacteria,1SSR3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1449509_0 697282.Mettu_2473 1.035e-164 530.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XDTZ@135618|Methylococcales 135618|Methylococcales S modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD SRR25158336_k127_1449509_1 1123296.JQKE01000015_gene1937 9.972e-18 85.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,2KR2F@206351|Neisseriales 206351|Neisseriales S Belongs to the UPF0307 family - - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 SRR25158336_k127_1449512_0 396588.Tgr7_1036 1.348e-237 739.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1WVVJ@135613|Chromatiales 135613|Chromatiales F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase SRR25158336_k127_1449512_4 105559.Nwat_2479 0.0002224 46.0 COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 SRR25158336_k127_1449512_2 1304275.C41B8_18462 1.767e-18 86.0 2DBQY@1|root,2ZAHD@2|Bacteria,1QYTK@1224|Proteobacteria,1T3V2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Transposase zinc-binding domain - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 SRR25158336_k127_1449512_1 631454.N177_0052 2.355e-76 269.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TV3X@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - - - - - - - - - - Lactonase,PQQ_2 SRR25158336_k127_1449512_3 1250005.PHEL85_2837 5.216e-05 52.0 COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,1HY5E@117743|Flavobacteriia,3VV3J@52959|Polaribacter 976|Bacteroidetes S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 SRR25158336_k127_1452460_2 1122604.JONR01000009_gene2341 4.745e-72 264.0 COG4943@1|root,COG4943@2|Bacteria,1MVTH@1224|Proteobacteria,1RMDP@1236|Gammaproteobacteria,1X4HG@135614|Xanthomonadales 135614|Xanthomonadales T signal transduction protein containing sensor and EAL domains - - - - - - - - - - - - CSS-motif,EAL SRR25158336_k127_1452460_1 1333998.M2A_1448 4.29e-76 261.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,4BSKE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Glycine zipper yiaD - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_YMGG,OmpA SRR25158336_k127_1452460_0 1255043.TVNIR_2413 2.382e-97 327.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales 135613|Chromatiales S Methyltransferase - - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 SRR25158336_k127_1459_2 105559.Nwat_0335 2.551e-24 103.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SRR25158336_k127_1459_3 1111728.ATYS01000013_gene4926 3.696e-19 91.0 2E9J1@1|root,333RY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SRR25158336_k127_1459_5 404589.Anae109_1481 5.102e-05 52.0 COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 SRR25158336_k127_1459_0 1163617.SCD_n02039 0.0 1107.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria 28216|Betaproteobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase SRR25158336_k127_1459_1 247633.GP2143_08469 3.111e-59 222.0 COG2199@1|root,COG3706@2|Bacteria,1QVPW@1224|Proteobacteria,1T2GC@1236|Gammaproteobacteria,1JAKM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg SRR25158336_k127_1465359_2 317025.Tcr_1049 1.675e-13 72.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,4631I@72273|Thiotrichales 72273|Thiotrichales CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA SRR25158336_k127_1465359_0 765910.MARPU_05510 1.268e-249 781.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1WWUB@135613|Chromatiales 135613|Chromatiales C Catalyzes the reversible hydration of fumarate to (S)- malate - - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C SRR25158336_k127_1465359_1 626887.J057_23895 6.911e-27 111.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,467RP@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1393 Arsenate reductase and related proteins, glutaredoxin family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC SRR25158336_k127_1479068_0 314278.NB231_07327 2.051e-88 300.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF SRR25158336_k127_1479068_1 2340.JV46_07510 4.856e-38 145.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1J96Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M MMPL family VP1286 - - ko:K07003 - - - - ko00000 - - - MMPL SRR25158336_k127_1485159_1 713586.KB900536_gene2555 2.077e-37 145.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1WYH1@135613|Chromatiales 135613|Chromatiales S PFAM FxsA cytoplasmic membrane protein - - - ko:K07113 - - - - ko00000 - - - FxsA SRR25158336_k127_1485159_2 572477.Alvin_1911 2.238e-30 131.0 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1WYXG@135613|Chromatiales 135613|Chromatiales P Divalent ion tolerance protein - - - ko:K03926 - - - - ko00000 - - - CutA1 SRR25158336_k127_1485159_0 713586.KB900536_gene2548 3.346e-41 159.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales 135613|Chromatiales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 SRR25158336_k127_1491286_3 1415756.JQMY01000001_gene3585 2.267e-18 84.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,2PDTQ@252301|Oceanicola 28211|Alphaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SRR25158336_k127_1491286_1 713586.KB900536_gene1350 1.621e-145 470.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1WW90@135613|Chromatiales 135613|Chromatiales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA SRR25158336_k127_1491286_4 1269813.ATUL01000023_gene635 3.123e-11 66.0 2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,1SGHN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K06950 - - - - ko00000 - - - - SRR25158336_k127_1491286_2 472759.Nhal_0597 8.613e-126 421.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 SRR25158336_k127_1491286_0 1198232.CYCME_2373 4.026e-181 576.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales 72273|Thiotrichales T PFAM response regulator receiver - - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat SRR25158336_k127_1495574_1 1304883.KI912532_gene1290 5.257e-13 75.0 COG0607@1|root,COG0607@2|Bacteria,1RDYR@1224|Proteobacteria,2VRSF@28216|Betaproteobacteria,2KXAZ@206389|Rhodocyclales 206389|Rhodocyclales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese SRR25158336_k127_1495574_2 248742.XP_005646266.1 5.876e-11 71.0 KOG4281@1|root,KOG4281@2759|Eukaryota,37IXP@33090|Viridiplantae,34MYF@3041|Chlorophyta 3041|Chlorophyta S PCO_ADO - - 1.13.11.19 ko:K10712 ko00430,ko01100,map00430,map01100 - R02467 RC00404 ko00000,ko00001,ko01000 - - - PCO_ADO SRR25158336_k127_1495574_3 386415.NT01CX_0311 5.492e-08 65.0 COG2391@1|root,COG2391@2|Bacteria,1V9KG@1239|Firmicutes,25DZD@186801|Clostridia,36I84@31979|Clostridiaceae 186801|Clostridia S YeeE YedE family protein - - - ko:K07112 - - - - ko00000 - - - Sulf_transp SRR25158336_k127_1495574_0 1049564.TevJSym_ag00640 2.152e-32 131.0 COG2854@1|root,COG2854@2|Bacteria,1NUHS@1224|Proteobacteria,1SN8R@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q MlaC protein - - - - - - - - - - - - MlaC SRR25158336_k127_1499501_3 1121937.AUHJ01000015_gene111 5.281e-36 141.0 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria 1236|Gammaproteobacteria O redox protein regulator of disulfide bond formation - - - - - - - - - - - - OsmC SRR25158336_k127_1499501_4 1123392.AQWL01000002_gene1757 2.474e-23 104.0 2EH48@1|root,338P5@2|Bacteria,1NFS9@1224|Proteobacteria,2W6NA@28216|Betaproteobacteria,1KT6V@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - SRR25158336_k127_1499501_0 247633.GP2143_16886 1.063e-102 345.0 COG1028@1|root,COG1028@2|Bacteria,1REA0@1224|Proteobacteria,1SMHH@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short SRR25158336_k127_1499501_1 279714.FuraDRAFT_1192 1.45e-96 320.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KQ1A@206351|Neisseriales 206351|Neisseriales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC SRR25158336_k127_1499501_2 1122613.ATUP01000001_gene757 6.02e-53 191.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,43WAY@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM SRR25158336_k127_1514407_1 395493.BegalDRAFT_2126 1.269e-123 402.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,460CM@72273|Thiotrichales 72273|Thiotrichales M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase SRR25158336_k127_1514407_0 395493.BegalDRAFT_3280 1.04e-181 580.0 COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,45ZVI@72273|Thiotrichales 72273|Thiotrichales GM Belongs to the mannose-6-phosphate isomerase type 2 family - - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase SRR25158336_k127_1517093_0 1453501.JELR01000001_gene2666 1.528e-89 297.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,4645X@72275|Alteromonadaceae 1236|Gammaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge SRR25158336_k127_1517093_2 1122194.AUHU01000002_gene2847 2.454e-28 123.0 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,4673V@72275|Alteromonadaceae 1236|Gammaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C SRR25158336_k127_1517093_1 1279017.AQYJ01000029_gene3406 1.634e-31 127.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945 BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 SRR25158336_k127_1519898_4 1198232.CYCME_2029 2.258e-31 126.0 COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,4619J@72273|Thiotrichales 72273|Thiotrichales S BON domain - - - - - - - - - - - - BON SRR25158336_k127_1519898_1 1042377.AFPJ01000035_gene2599 3.392e-144 466.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C SRR25158336_k127_1519898_0 1049564.TevJSym_ac01890 2.249e-181 578.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1J4NG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 SRR25158336_k127_1519898_2 1301098.PKB_1052 9.685e-100 340.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 SRR25158336_k127_1519898_3 765912.Thimo_1889 4.067e-37 147.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1WY25@135613|Chromatiales 135613|Chromatiales S protein conserved in bacteria - - - - - - - - - - - - TPR_21 SRR25158336_k127_1519960_5 1121937.AUHJ01000003_gene3216 1.032e-05 50.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,466AI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD SRR25158336_k127_1519960_4 1163617.SCD_n01962 1.945e-07 58.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,2VKYR@28216|Betaproteobacteria 28216|Betaproteobacteria T HDOD domain - - - - - - - - - - - - HDOD SRR25158336_k127_1519960_2 2340.JV46_22660 5.756e-59 213.0 COG4623@1|root,COG4623@2|Bacteria,1QUQJ@1224|Proteobacteria,1T218@1236|Gammaproteobacteria,1JBK3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT SRR25158336_k127_1519960_3 1049564.TevJSym_ag00500 1.696e-23 105.0 2C3QB@1|root,33D78@2|Bacteria,1P49C@1224|Proteobacteria,1SUEH@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF350 SRR25158336_k127_1519960_0 1236542.BALM01000008_gene2958 1.172e-119 405.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,2QA7M@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM MscS Mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel SRR25158336_k127_1519960_1 1283300.ATXB01000001_gene2242 9.76e-68 236.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S6JM@1236|Gammaproteobacteria,1XE76@135618|Methylococcales 135618|Methylococcales S Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 SRR25158336_k127_1522448_1 1163617.SCD_n02471 2.396e-78 267.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the Nudix hydrolase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,TMP-TENI SRR25158336_k127_1522448_0 56110.Oscil6304_3938 5.551e-121 400.0 COG0659@1|root,COG0659@2|Bacteria,1G0E3@1117|Cyanobacteria,1H7B8@1150|Oscillatoriales 1117|Cyanobacteria P Sulfate transporter - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp SRR25158336_k127_1529305_1 2340.JV46_02970 2.317e-81 273.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase SRR25158336_k127_1529305_2 2340.JV46_02960 3.05e-72 250.0 COG0398@1|root,COG0607@1|root,COG0398@2|Bacteria,COG0607@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P SNARE associated Golgi protein ydjX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Rhodanese,SNARE_assoc SRR25158336_k127_1529305_0 713586.KB900536_gene217 4.433e-156 507.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X01C@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.16.1.1 ko:K00520 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim SRR25158336_k127_1529305_3 314345.SPV1_03473 2.592e-47 172.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria 1224|Proteobacteria T radical SAM - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM SRR25158336_k127_1535999_1 305900.GV64_17580 7.066e-112 367.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1XHYG@135619|Oceanospirillales 135619|Oceanospirillales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding SRR25158336_k127_1535999_0 1335757.SPICUR_00370 1.449e-171 549.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iE2348C_1286.E2348C_4372,iJN746.PP_4187 Pyr_redox_2,Pyr_redox_dim SRR25158336_k127_1537928_0 313612.L8106_12840 5.575e-16 92.0 COG1520@1|root,COG2911@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria,1H8AY@1150|Oscillatoriales 1117|Cyanobacteria Q COG2931 RTX toxins and related Ca2 -binding - - - - - - - - - - - - Calx-beta,DUF4347,FG-GAP,HemolysinCabind,SdrD_B SRR25158336_k127_1543729_2 2340.JV46_10310 7.004e-64 220.0 COG3439@1|root,COG3439@2|Bacteria,1REDZ@1224|Proteobacteria,1RPW4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 SRR25158336_k127_1543729_3 1049564.TevJSym_aj00740 4.32e-23 104.0 28T0P@1|root,2ZF9Z@2|Bacteria,1RAUV@1224|Proteobacteria,1S23D@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1543729_0 1049564.TevJSym_aa01890 3.262e-174 560.0 COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Dynamin family - - - - - - - - - - - - Dynamin_N SRR25158336_k127_1543729_1 498761.HM1_1843 1.125e-80 278.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia 186801|Clostridia KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iHN637.CLJU_RS16615 ACT_4,HD_4,RelA_SpoT,TGS SRR25158336_k127_1546424_0 1249627.D779_3071 7.119e-259 811.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales 135613|Chromatiales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS SRR25158336_k127_1546424_1 472759.Nhal_3944 2.339e-174 557.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1WWG8@135613|Chromatiales 135613|Chromatiales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 SRR25158336_k127_1546424_4 1163617.SCD_n01922 2.891e-50 183.0 COG1047@1|root,COG1047@2|Bacteria,1N0ZF@1224|Proteobacteria,2W2PN@28216|Betaproteobacteria 28216|Betaproteobacteria O Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C SRR25158336_k127_1546424_3 472759.Nhal_3945 6.929e-55 195.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N SRR25158336_k127_1546424_2 572477.Alvin_0046 1.749e-98 323.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1WW2C@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N SRR25158336_k127_1552357_2 1000565.METUNv1_00660 2.899e-07 57.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - 4HB_MCP_1,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_7,PAS_8,PAS_9,Response_reg SRR25158336_k127_1552357_1 633149.Bresu_2806 8.024e-33 134.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,2UIQD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1552357_0 572477.Alvin_0312 6e-194 609.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1WWRH@135613|Chromatiales 135613|Chromatiales G Fructose-bisphosphate aldolase, class II, Calvin cycle subtype - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase SRR25158336_k127_1554012_0 472759.Nhal_2451 1.131e-135 436.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales 135613|Chromatiales E TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SRR25158336_k127_1554012_1 713586.KB900536_gene141 1.133e-117 389.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1WW47@135613|Chromatiales 135613|Chromatiales J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 SRR25158336_k127_1554012_2 2340.JV46_15060 3.503e-116 381.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1J4Y4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS SRR25158336_k127_1554012_3 748658.KB907315_gene2470 5.203e-95 317.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase SRR25158336_k127_1554012_4 396588.Tgr7_1162 1.521e-75 258.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1WY5S@135613|Chromatiales 135613|Chromatiales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF SRR25158336_k127_1556869_0 1049564.TevJSym_ab01850 4.057e-93 316.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1J4XV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N SRR25158336_k127_1556869_1 187272.Mlg_0559 4.381e-51 192.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1WWGT@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ SRR25158336_k127_1557129_1 380394.Lferr_1058 1.99e-57 204.0 COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,2NC25@225057|Acidithiobacillales 225057|Acidithiobacillales S 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 SRR25158336_k127_1557129_0 1123393.KB891326_gene83 2.701e-253 792.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1KSJ5@119069|Hydrogenophilales 119069|Hydrogenophilales L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_thumb,HHH_5,HHH_8 SRR25158336_k127_1557377_0 99598.Cal7507_0411 2.813e-103 342.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1HM7U@1161|Nostocales 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR SRR25158336_k127_1557377_4 1049564.TevJSym_aa02000 5.484e-37 147.0 COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,1S8AC@1236|Gammaproteobacteria,1J70V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG SRR25158336_k127_1557377_1 686340.Metal_0899 8.842e-89 303.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XDR3@135618|Methylococcales 135618|Methylococcales K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 SRR25158336_k127_1557377_2 1026882.MAMP_02916 2.119e-48 182.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,4610E@72273|Thiotrichales 72273|Thiotrichales K Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase SRR25158336_k127_1557377_5 521719.ATXQ01000019_gene1662 8.046e-06 56.0 2E02Y@1|root,32VRV@2|Bacteria,1N1HZ@1224|Proteobacteria,1S93X@1236|Gammaproteobacteria,1YCXD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - SPOR SRR25158336_k127_1557377_6 1122201.AUAZ01000056_gene35 9.159e-05 48.0 2AWWV@1|root,31NUD@2|Bacteria,1QPF3@1224|Proteobacteria,1SJ55@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1557377_3 1163617.SCD_n01412 3.428e-42 162.0 COG2199@1|root,COG2200@1|root,COG2203@1|root,COG3290@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,1RGKE@1224|Proteobacteria 1224|Proteobacteria T GAF domain - - 3.1.4.52 ko:K20962 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - EAL,GAF,GAF_2,GGDEF,HWE_HK,PAS,PAS_3,PAS_4,PAS_8 SRR25158336_k127_1557383_3 1123401.JHYQ01000015_gene1412 5.272e-40 153.0 2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,1S97C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1557383_2 2340.JV46_21930 2.22e-41 154.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_5 SRR25158336_k127_1557383_0 1049564.TevJSym_bb00300 1.622e-124 404.0 COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,1S0ZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT Response regulator receiver - - - - - - - - - - - - PAS,PAS_9,Response_reg SRR25158336_k127_1557383_1 290397.Adeh_4122 1.357e-51 190.0 COG0784@1|root,COG0840@1|root,COG1511@1|root,COG4251@1|root,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2YU1H@29|Myxococcales 28221|Deltaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Response_reg SRR25158336_k127_1564762_3 7176.CPIJ016498-PA 1.646e-16 88.0 2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,41W09@6656|Arthropoda,3SING@50557|Insecta,44Y9H@7147|Diptera 33208|Metazoa O Calcium ion binding. It is involved in the biological process described with cell adhesion - - - ko:K04659 ko04145,ko04151,ko04510,ko04512,ko05144,ko05165,map04145,map04151,map04510,map04512,map05144,map05165 - - - ko00000,ko00001,ko00536,ko04131,ko04147,ko04516 - - - EGF_CA,TSP_3,TSP_C SRR25158336_k127_1564762_2 1198232.CYCME_2191 5.09e-40 152.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,1SAXA@1236|Gammaproteobacteria,462P4@72273|Thiotrichales 72273|Thiotrichales K Ferric uptake regulator family - - - ko:K09826 - - - - ko00000,ko03000 - - - FUR SRR25158336_k127_1564762_1 713586.KB900536_gene2034 4.895e-104 349.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1WWA9@135613|Chromatiales 135613|Chromatiales C PFAM FAD dependent oxidoreductase - - 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO SRR25158336_k127_1564762_0 264730.PSPPH_0724 6.51e-123 398.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1Z5SH@136849|Pseudomonas syringae group 1236|Gammaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024 LYTB SRR25158336_k127_1565137_1 870187.Thini_2729 2.665e-88 294.0 arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,460KA@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 SRR25158336_k127_1565137_0 1278309.KB907099_gene2444 2.294e-106 353.0 arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF1538) - - - - - - - - - - - - DUF1538 SRR25158336_k127_1565137_2 1201293.AKXQ01000001_gene2086 1.81e-41 155.0 COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the P(II) protein family VV0993 - - - - - - - - - - - - SRR25158336_k127_1567425_1 1286106.MPL1_03293 2.048e-69 241.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,45ZZA@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO SRR25158336_k127_1567425_0 187272.Mlg_0693 1.43e-137 448.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 SRR25158336_k127_1569713_1 870187.Thini_1552 1.197e-65 229.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,4609I@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A SRR25158336_k127_1569713_0 396588.Tgr7_2774 2.596e-213 673.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C SRR25158336_k127_1576581_1 580332.Slit_1670 1.673e-78 273.0 COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,2W0RY@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - - SRR25158336_k127_1576581_2 519989.ECTPHS_03192 1.318e-42 158.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1WYBV@135613|Chromatiales 135613|Chromatiales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS SRR25158336_k127_1576581_0 1122164.JHWF01000004_gene15 3.228e-187 593.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1JCZN@118969|Legionellales 118969|Legionellales O C-terminal, D2-small domain, of ClpB protein clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N SRR25158336_k127_1577924_0 323261.Noc_3087 1.867e-177 571.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas SRR25158336_k127_1577924_1 1049564.TevJSym_aq00320 2.554e-150 486.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1J4DQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N SRR25158336_k127_1578727_1 498211.CJA_3381 1.429e-32 136.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 SRR25158336_k127_1578727_0 1323663.AROI01000004_gene2087 1.847e-198 625.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria 1236|Gammaproteobacteria C UPF0313 protein ygiQ - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N SRR25158336_k127_1582116_0 1163617.SCD_n01613 1.046e-233 737.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria 28216|Betaproteobacteria P Ferrous iron transport protein B feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate SRR25158336_k127_1582116_1 395494.Galf_2202 6.684e-10 64.0 COG1918@1|root,COG1918@2|Bacteria,1NA6D@1224|Proteobacteria,2VY9N@28216|Betaproteobacteria,44W2B@713636|Nitrosomonadales 28216|Betaproteobacteria P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA SRR25158336_k127_1585099_1 1049564.TevJSym_bb00370 3.099e-18 89.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1J5V1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase SRR25158336_k127_1585099_0 1318628.MARLIPOL_15157 3.585e-200 635.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae 1236|Gammaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 SRR25158336_k127_1586195_0 1123368.AUIS01000033_gene1383 7.264e-64 223.0 COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,2NDJP@225057|Acidithiobacillales 225057|Acidithiobacillales C D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C SRR25158336_k127_1586195_2 243233.MCA1536 9.214e-54 198.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1XEED@135618|Methylococcales 135618|Methylococcales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N SRR25158336_k127_1586195_3 1122599.AUGR01000005_gene1732 1.382e-09 66.0 COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1SE1A@1236|Gammaproteobacteria,1XKWE@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09908 - - - - ko00000 - - - DUF1043 SRR25158336_k127_1586195_1 765911.Thivi_4153 5.613e-57 201.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales 135613|Chromatiales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 SRR25158336_k127_1586195_4 1163617.SCD_n02318 1.637e-09 60.0 2EA5W@1|root,334AS@2|Bacteria,1NFAR@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_1586991_2 1049564.TevJSym_as00390 1.832e-91 304.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM SRR25158336_k127_1586991_3 1123392.AQWL01000004_gene2785 1.136e-30 128.0 COG3637@1|root,COG3637@2|Bacteria,1PWS4@1224|Proteobacteria,2WAG8@28216|Betaproteobacteria,1KTGR@119069|Hydrogenophilales 119069|Hydrogenophilales M Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL SRR25158336_k127_1586991_0 631362.Thi970DRAFT_04690 5.611e-166 528.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 135613|Chromatiales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP SRR25158336_k127_1586991_1 1123368.AUIS01000023_gene933 2.436e-100 353.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 SRR25158336_k127_158835_6 545276.KB898729_gene1545 1.856e-25 106.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1WWD5@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 SRR25158336_k127_158835_1 713586.KB900536_gene2343 8.591e-125 403.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1WWD5@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 SRR25158336_k127_158835_4 1123261.AXDW01000003_gene1813 3.226e-53 191.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1X6FE@135614|Xanthomonadales 135614|Xanthomonadales J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase SRR25158336_k127_158835_2 396588.Tgr7_0213 4.888e-99 325.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1WVVY@135613|Chromatiales 135613|Chromatiales E imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD SRR25158336_k127_158835_3 243233.MCA2804 3.807e-79 269.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XDZU@135618|Methylococcales 135618|Methylococcales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase SRR25158336_k127_158835_0 396588.Tgr7_0215 1.48e-125 405.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1WXHX@135613|Chromatiales 135613|Chromatiales E TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth SRR25158336_k127_158835_5 2340.JV46_18600 4.506e-35 134.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1J5IF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - ko:K01663,ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481 His_biosynth SRR25158336_k127_1589547_1 396588.Tgr7_2971 2.188e-122 400.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1WX8X@135613|Chromatiales 135613|Chromatiales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N SRR25158336_k127_1589547_0 1026882.MAMP_00233 2.891e-155 499.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,45ZWK@72273|Thiotrichales 72273|Thiotrichales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase SRR25158336_k127_1589732_2 1123392.AQWL01000003_gene417 4.701e-64 226.0 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2WGE2@28216|Betaproteobacteria,1KSQD@119069|Hydrogenophilales 119069|Hydrogenophilales G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 SRR25158336_k127_1589732_0 1163617.SCD_n01091 8.957e-121 397.0 COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria 28216|Betaproteobacteria GK ROK family nagK - 2.7.1.2,2.7.1.4,2.7.1.59 ko:K00845,ko:K00847,ko:K00884 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R00760,R00867,R01201,R01600,R01786,R03920 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK SRR25158336_k127_1589732_3 395493.BegalDRAFT_0680 2.817e-28 119.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,4616X@72273|Thiotrichales 72273|Thiotrichales O Subtilase family - - - - - - - - - - - - Peptidase_S8 SRR25158336_k127_1589732_1 870187.Thini_1279 1.648e-97 324.0 COG1893@1|root,COG1893@2|Bacteria,1R60C@1224|Proteobacteria,1RZQZ@1236|Gammaproteobacteria,460EC@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - SRR25158336_k127_1589732_4 1000565.METUNv1_03348 7.998e-15 80.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales 206389|Rhodocyclales P ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 SRR25158336_k127_1590733_1 1265313.HRUBRA_00727 3.104e-27 114.0 COG1575@1|root,COG1575@2|Bacteria,1QJ69@1224|Proteobacteria,1TH3V@1236|Gammaproteobacteria,1J61G@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H UbiA prenyltransferase family - - - - - - - - - - - - UbiA SRR25158336_k127_1590733_2 998674.ATTE01000001_gene4002 1.912e-21 97.0 2EG9Y@1|root,33A1R@2|Bacteria,1NMAJ@1224|Proteobacteria,1SHG1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein structure with unknown function - - - - - - - - - - - - DUF4144 SRR25158336_k127_1590733_0 1122604.JONR01000006_gene2533 2.821e-159 506.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1X4DA@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM SRR25158336_k127_1590733_3 1348657.M622_05950 1.094e-12 68.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB SRR25158336_k127_1597051_4 396595.TK90_1509 0.0001742 47.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1WYRX@135613|Chromatiales 135613|Chromatiales S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC SRR25158336_k127_1597051_3 765911.Thivi_1028 2.224e-74 258.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1WXXM@135613|Chromatiales 135613|Chromatiales S HAD-superfamily hydrolase, subfamily IA, variant 1 - - 3.1.3.105 ko:K22292 ko00520,map00520 - R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 SRR25158336_k127_1597051_2 1117647.M5M_02505 7.858e-106 347.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1J584@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 SRR25158336_k127_1597051_0 713586.KB900536_gene585 3.636e-180 574.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales 135613|Chromatiales F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 SRR25158336_k127_1597051_1 396588.Tgr7_1533 6.437e-110 361.0 COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1WY8X@135613|Chromatiales 135613|Chromatiales M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix SRR25158336_k127_1608809_3 243233.MCA1850 5.378e-16 79.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1XFJU@135618|Methylococcales 135618|Methylococcales J CRS1_YhbY - - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY SRR25158336_k127_1608809_2 1434929.X946_4125 1.489e-17 87.0 2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,1KFR2@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4149) - - - - - - - - - - - - DUF4149 SRR25158336_k127_1608809_1 187272.Mlg_1980 7.991e-65 225.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales 135613|Chromatiales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N SRR25158336_k127_1608809_0 187272.Mlg_1981 5.563e-115 376.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS SRR25158336_k127_1609323_2 472759.Nhal_0529 1.52e-36 139.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB SRR25158336_k127_1609323_1 1049564.TevJSym_al00470 9.125e-38 145.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1J6HT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0848 Biopolymer transport protein exbD1 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD SRR25158336_k127_1609323_0 323261.Noc_2676 3.377e-101 336.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales 135613|Chromatiales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK SRR25158336_k127_161007_2 765912.Thimo_2954 1.024e-53 190.0 COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,1S5Y6@1236|Gammaproteobacteria,1WYHX@135613|Chromatiales 135613|Chromatiales CQ carboxysome shell protein - - - - - - - - - - - - BMC SRR25158336_k127_161007_3 713587.THITH_12330 2.697e-49 177.0 COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,1S5Y6@1236|Gammaproteobacteria,1WYQG@135613|Chromatiales 135613|Chromatiales CQ BMC - - - - - - - - - - - - BMC SRR25158336_k127_161007_4 713587.THITH_12325 4.981e-48 175.0 COG2193@1|root,COG2193@2|Bacteria,1PE4V@1224|Proteobacteria,1SAG5@1236|Gammaproteobacteria,1WZ24@135613|Chromatiales 135613|Chromatiales P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin SRR25158336_k127_161007_6 713587.THITH_12320 2.542e-29 119.0 COG2154@1|root,COG2154@2|Bacteria,1NKCS@1224|Proteobacteria,1SDBU@1236|Gammaproteobacteria,1WZE1@135613|Chromatiales 135613|Chromatiales H Pterin 4 alpha carbinolamine dehydratase - - - - - - - - - - - - 1-cysPrx_C,Pterin_4a SRR25158336_k127_161007_1 768671.ThimaDRAFT_3591 2.194e-60 214.0 COG1192@1|root,COG1192@2|Bacteria,1MWRE@1224|Proteobacteria,1S53U@1236|Gammaproteobacteria,1WXF9@135613|Chromatiales 135613|Chromatiales D Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SRR25158336_k127_161007_0 1255043.TVNIR_2978 9.367e-146 470.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1WWK0@135613|Chromatiales 135613|Chromatiales K LysR family - - - ko:K21703 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate SRR25158336_k127_161007_5 768671.ThimaDRAFT_4729 5.564e-46 168.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1WX3W@135613|Chromatiales 135613|Chromatiales U Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp SRR25158336_k127_1616811_1 187272.Mlg_1378 5.02e-107 368.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L SRR25158336_k127_1616811_0 105559.Nwat_2721 2.726e-184 586.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WWMQ@135613|Chromatiales 135613|Chromatiales C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SRR25158336_k127_1616811_2 713586.KB900536_gene1215 1.339e-62 220.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1WWMK@135613|Chromatiales 135613|Chromatiales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE SRR25158336_k127_1620388_1 765912.Thimo_0530 4.995e-61 214.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales 135613|Chromatiales T low molecular weight - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc SRR25158336_k127_1620388_3 1318628.MARLIPOL_01590 4.108e-07 57.0 293UA@1|root,2ZR9K@2|Bacteria,1P60N@1224|Proteobacteria,1SVZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ SRR25158336_k127_1620388_0 572477.Alvin_1019 3.601e-89 300.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1WWTZ@135613|Chromatiales 135613|Chromatiales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 SRR25158336_k127_1620388_2 335283.Neut_2110 1.236e-20 92.0 COG1663@1|root,COG2835@1|root,COG1663@2|Bacteria,COG2835@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,372MY@32003|Nitrosomonadales 28216|Betaproteobacteria F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK SRR25158336_k127_1621029_0 1049564.TevJSym_ak00590 3.964e-273 851.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1J5IS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d SRR25158336_k127_1621029_1 713586.KB900536_gene2406 1.319e-31 131.0 COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR SRR25158336_k127_1633692_1 32057.KB217478_gene5047 1.951e-28 123.0 COG0500@1|root,COG2226@2|Bacteria,1G7KV@1117|Cyanobacteria,1HMWU@1161|Nostocales 1117|Cyanobacteria Q Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - Methyltransf_12,Methyltransf_25,Methyltransf_31 SRR25158336_k127_1633692_0 1266914.ATUK01000011_gene2362 3.493e-57 211.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales 135613|Chromatiales H Uroporphyrinogen III synthase - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 SRR25158336_k127_1633692_2 349124.Hhal_1025 4.769e-23 100.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1WVWF@135613|Chromatiales 135613|Chromatiales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC SRR25158336_k127_1634494_2 1149133.ppKF707_1768 3.837e-27 118.0 COG0398@1|root,COG0398@2|Bacteria,1RDYV@1224|Proteobacteria,1SA20@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Pfam SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SRR25158336_k127_1634494_1 1500890.JQNL01000001_gene2002 1.328e-75 260.0 COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,1S22P@1236|Gammaproteobacteria,1X3J4@135614|Xanthomonadales 135614|Xanthomonadales M Dolichol-phosphate mannosyltransferase dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SRR25158336_k127_1634494_0 396588.Tgr7_2744 6.938e-261 820.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH SRR25158336_k127_1637676_1 55529.EKX34102 2.161e-05 46.0 COG0545@1|root,KOG0549@2759|Eukaryota 55529.EKX34102|- O peptidyl-prolyl cis-trans isomerase activity - - - - - - - - - - - - - SRR25158336_k127_1637676_0 1129374.AJE_07865 6.012e-115 390.0 COG2755@1|root,COG2755@2|Bacteria,1R43M@1224|Proteobacteria,1RRTK@1236|Gammaproteobacteria,465MH@72275|Alteromonadaceae 1236|Gammaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 SRR25158336_k127_1638604_0 396588.Tgr7_1100 3.677e-126 407.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1WX3I@135613|Chromatiales 135613|Chromatiales E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR25158336_k127_1638604_1 1116472.MGMO_88c00180 2.135e-20 104.0 COG2911@1|root,COG2911@2|Bacteria,1MW9V@1224|Proteobacteria,1S3FX@1236|Gammaproteobacteria,1XDS4@135618|Methylococcales 135618|Methylococcales S Protein conserved in bacteria - - - - - - - - - - - - - SRR25158336_k127_1641981_2 472759.Nhal_2699 1.434e-05 48.0 COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,1WVYZ@135613|Chromatiales 135613|Chromatiales G TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - - - - - - - - - - HAD_2 SRR25158336_k127_1641981_0 396588.Tgr7_2043 5.236e-159 511.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 SRR25158336_k127_1641981_1 765912.Thimo_1655 7.146e-76 261.0 COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1WWYG@135613|Chromatiales 135613|Chromatiales E High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway cysZ - - ko:K06203 - - - - ko00000 - - - DnaJ,EI24 SRR25158336_k127_164858_0 396588.Tgr7_0974 9.617e-127 409.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1WXGX@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N SRR25158336_k127_164858_1 1001530.BACE01000024_gene1579 1.031e-93 312.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XV0G@135623|Vibrionales 135623|Vibrionales F carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase SRR25158336_k127_1649989_6 1123073.KB899244_gene287 6.418e-07 51.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1X367@135614|Xanthomonadales 135614|Xanthomonadales I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 SRR25158336_k127_1649989_2 998674.ATTE01000001_gene1691 2.706e-102 338.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,45ZWN@72273|Thiotrichales 72273|Thiotrichales IQ reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR25158336_k127_1649989_4 187272.Mlg_1420 5.92e-34 132.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1WYUG@135613|Chromatiales 135613|Chromatiales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding SRR25158336_k127_1649989_0 713586.KB900536_gene662 2.389e-196 618.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1WWGC@135613|Chromatiales 135613|Chromatiales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SRR25158336_k127_1649989_1 314278.NB231_06950 4.874e-154 499.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales 135613|Chromatiales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind SRR25158336_k127_1649989_3 519989.ECTPHS_03227 9.978e-75 263.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 SRR25158336_k127_1649989_5 1049564.TevJSym_bc00190 1.516e-30 126.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1J56S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG SRR25158336_k127_1650712_0 2340.JV46_06590 1.269e-305 949.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1J8KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941 Alpha-amylase,Alpha-amylase_C,CBM_48 SRR25158336_k127_1650712_2 998674.ATTE01000001_gene1089 5.188e-163 525.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,45ZQG@72273|Thiotrichales 72273|Thiotrichales G 4-alpha-glucanotransferase - - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 SRR25158336_k127_1650712_1 292415.Tbd_2060 1.807e-175 561.0 COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,1KS0Q@119069|Hydrogenophilales 119069|Hydrogenophilales G Glycosyl hydrolase family 57 - - - - - - - - - - - - Glyco_hydro_57 SRR25158336_k127_1655399_0 1335757.SPICUR_01180 2.754e-117 383.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1WWRE@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 SRR25158336_k127_1655399_1 1116472.MGMO_146c00020 2.076e-41 155.0 COG3272@1|root,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XEGF@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 SRR25158336_k127_1655863_2 886293.Sinac_5864 3.335e-51 184.0 COG0720@1|root,COG0720@2|Bacteria,2J000@203682|Planctomycetes 203682|Planctomycetes H COG0720 6-pyruvoyl-tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS SRR25158336_k127_1655863_0 1049564.TevJSym_ao00510 3.75e-115 380.0 COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 SRR25158336_k127_1655863_1 157783.LK03_14125 2.878e-94 311.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b2323,iAPECO1_1312.APECO1_4241,iB21_1397.B21_02208,iBWG_1329.BWG_2097,iE2348C_1286.E2348C_2463,iEC042_1314.EC042_2564,iEC55989_1330.EC55989_2567,iECABU_c1320.ECABU_c26560,iECBD_1354.ECBD_1336,iECB_1328.ECB_02248,iECDH10B_1368.ECDH10B_2485,iECDH1ME8569_1439.ECDH1ME8569_2261,iECD_1391.ECD_02248,iECED1_1282.ECED1_2787,iECIAI1_1343.ECIAI1_2400,iECIAI39_1322.ECIAI39_2472,iECNA114_1301.ECNA114_2414,iECO103_1326.ECO103_2787,iECO111_1330.ECO111_3071,iECO26_1355.ECO26_3311,iECOK1_1307.ECOK1_2605,iECP_1309.ECP_2362,iECS88_1305.ECS88_2471,iECSE_1348.ECSE_2632,iECSF_1327.ECSF_2200,iECUMN_1333.ECUMN_2663,iECW_1372.ECW_m2512,iEKO11_1354.EKO11_1442,iETEC_1333.ETEC_2459,iEcDH1_1363.EcDH1_1333,iEcHS_1320.EcHS_A2474,iEcSMS35_1347.EcSMS35_2480,iEcolC_1368.EcolC_1329,iJN746.PP_4175,iJO1366.b2323,iJR904.b2323,iLF82_1304.LF82_0605,iNRG857_1313.NRG857_11765,iSBO_1134.SBO_2360,iUMN146_1321.UM146_05195,iUTI89_1310.UTI89_C2608,iWFL_1372.ECW_m2512,iY75_1357.Y75_RS12180,ic_1306.c2869 Ketoacyl-synt_C,ketoacyl-synt SRR25158336_k127_1656598_3 1151116.Q7S_17030 9.695e-23 100.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,3FGJ8@34037|Rahnella 1236|Gammaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG SRR25158336_k127_1656598_2 1123514.KB905899_gene1621 4.65e-35 137.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,4613V@72273|Thiotrichales 72273|Thiotrichales U Preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC SRR25158336_k127_1656598_0 207954.MED92_17349 3.17e-184 584.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XHH8@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT SRR25158336_k127_1656598_1 768066.HELO_1403 1.952e-131 427.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XH6Q@135619|Oceanospirillales 135619|Oceanospirillales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth SRR25158336_k127_1662178_1 323261.Noc_1603 9.673e-246 767.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 SRR25158336_k127_1662178_0 105559.Nwat_1523 0.0 1715.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales 135613|Chromatiales E glutamate synthase - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase SRR25158336_k127_1665356_0 713586.KB900536_gene372 5.365e-297 921.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales 135613|Chromatiales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SRR25158336_k127_1665356_1 765912.Thimo_0465 1.412e-32 130.0 COG2142@1|root,COG2142@2|Bacteria,1RH1K@1224|Proteobacteria,1S7GT@1236|Gammaproteobacteria,1WYKS@135613|Chromatiales 135613|Chromatiales C Succinate dehydrogenase hydrophobic membrane anchor - - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt SRR25158336_k127_1665356_2 2340.JV46_18230 3.88e-31 125.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,1S5ZE@1236|Gammaproteobacteria,1J6QM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt SRR25158336_k127_1667213_1 713586.KB900536_gene2345 5.547e-38 154.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding SRR25158336_k127_1667213_0 261292.Nit79A3_2905 2.606e-58 205.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,372GH@32003|Nitrosomonadales 28216|Betaproteobacteria L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP SRR25158336_k127_1671805_5 519989.ECTPHS_02551 3.153e-05 47.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales 135613|Chromatiales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD SRR25158336_k127_1671805_2 1134474.O59_003725 5.73e-125 408.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1FFTZ@10|Cellvibrio 1236|Gammaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_0056 PdxA SRR25158336_k127_1671805_1 472759.Nhal_2085 8.71e-127 419.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales 135613|Chromatiales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N SRR25158336_k127_1671805_0 396588.Tgr7_2714 2.177e-167 557.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales 135613|Chromatiales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C SRR25158336_k127_1671805_4 1049564.TevJSym_ao00270 2.997e-67 243.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SRR25158336_k127_1671805_3 1049564.TevJSym_ao00280 1.023e-82 281.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1224|Proteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran SRR25158336_k127_168383_0 519989.ECTPHS_04239 8.37e-230 724.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS SRR25158336_k127_16861_0 686340.Metal_1844 0.0 1265.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XE0B@135618|Methylococcales 135618|Methylococcales H Vitamin B12 dependent methionine synthase, activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans SRR25158336_k127_17178_3 2340.JV46_07570 2.285e-37 141.0 COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,1J6R4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 SRR25158336_k127_17178_1 472759.Nhal_2557 8.16e-88 299.0 COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,1S3T8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ribonuclease BN - - - - - - - - - - - - Virul_fac_BrkB SRR25158336_k127_17178_0 338963.Pcar_0271 9.586e-109 364.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,43UX8@69541|Desulfuromonadales 28221|Deltaproteobacteria I PLD-like domain - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 SRR25158336_k127_17178_2 1049564.TevJSym_ak00260 7.733e-45 166.0 COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria 1224|Proteobacteria S Lipase maturation factor - - - - - - - - - - - - DUF393,LMF1 SRR25158336_k127_172586_10 323848.Nmul_A1627 5.425e-18 85.0 COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,2VUVC@28216|Betaproteobacteria,373CJ@32003|Nitrosomonadales 28216|Betaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX SRR25158336_k127_172586_0 314278.NB231_05811 4.763e-232 725.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD SRR25158336_k127_172586_4 768671.ThimaDRAFT_0883 1.294e-114 376.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales 135613|Chromatiales S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase SRR25158336_k127_172586_3 519989.ECTPHS_02991 4.065e-131 463.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales 135613|Chromatiales S Protein of unknown function - - - - - - - - - - - - AsmA_2,DUF3971 SRR25158336_k127_172586_1 519989.ECTPHS_02996 5.852e-203 642.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales 135613|Chromatiales J TIGRFAM ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 SRR25158336_k127_172586_7 765911.Thivi_4099 2.771e-63 222.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales 135613|Chromatiales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf SRR25158336_k127_172586_8 768671.ThimaDRAFT_0879 9.439e-63 218.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1WY5P@135613|Chromatiales 135613|Chromatiales J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase SRR25158336_k127_172586_9 713586.KB900536_gene1095 1.716e-34 136.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1WYQV@135613|Chromatiales 135613|Chromatiales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS SRR25158336_k127_172586_6 396588.Tgr7_2275 1.414e-68 239.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales 135613|Chromatiales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like SRR25158336_k127_172586_2 870187.Thini_0552 2.004e-191 606.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,45ZMN@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SRR25158336_k127_172586_5 396588.Tgr7_2277 1.417e-105 352.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta SRR25158336_k127_172586_11 519989.ECTPHS_03031 3.762e-14 77.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1WY80@135613|Chromatiales 135613|Chromatiales M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE SRR25158336_k127_174673_3 754476.Q7A_2839 1.062e-40 152.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales 72273|Thiotrichales EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N SRR25158336_k127_174673_2 717774.Marme_3469 2.616e-52 193.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XJFN@135619|Oceanospirillales 135619|Oceanospirillales O Thiol disulfide interchange protein dsbA - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA SRR25158336_k127_174673_0 1198232.CYCME_2487 1.521e-177 563.0 COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,1RX07@1236|Gammaproteobacteria,45ZPJ@72273|Thiotrichales 72273|Thiotrichales O PFAM Cytochrome c assembly protein - - - - - - - - - - - - Cytochrom_C_asm SRR25158336_k127_174673_1 754476.Q7A_744 9.745e-132 433.0 COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,1RXXZ@1236|Gammaproteobacteria,46045@72273|Thiotrichales 72273|Thiotrichales O Cytochrome c-type biogenesis protein Ccs1 ResB - - - ko:K07399 - - - - ko00000 - - - ResB SRR25158336_k127_179326_0 1049564.TevJSym_ag01090 0.0 1109.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1J526@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom SRR25158336_k127_179326_2 1123401.JHYQ01000020_gene919 3.815e-50 184.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,4612Y@72273|Thiotrichales 72273|Thiotrichales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC SRR25158336_k127_179326_1 768671.ThimaDRAFT_2739 2.67e-152 486.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1WX13@135613|Chromatiales 135613|Chromatiales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas SRR25158336_k127_179326_3 1198232.CYCME_0392 1.616e-31 124.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,4613M@72273|Thiotrichales 72273|Thiotrichales S Sodium Bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF SRR25158336_k127_183647_1 1292034.OR37_02684 4.049e-07 57.0 2DC1J@1|root,32TYP@2|Bacteria,1N5X9@1224|Proteobacteria,2VGQR@28211|Alphaproteobacteria,2KK6P@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - SRR25158336_k127_183647_0 1026882.MAMP_00478 8.709e-148 484.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,4607H@72273|Thiotrichales 72273|Thiotrichales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K11747 - - - - ko00000,ko02000 2.A.37.1.2 - - Na_H_Exchanger,TrkA_N SRR25158336_k127_185420_2 1283300.ATXB01000002_gene3125 1.165e-18 86.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1XDX1@135618|Methylococcales 135618|Methylococcales O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3 SRR25158336_k127_185420_3 314278.NB231_02078 2.882e-12 77.0 COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1WWDH@135613|Chromatiales 135613|Chromatiales D Belongs to the ParA family - - - ko:K04562 - - - - ko00000,ko02035 - - - CbiA,ParA SRR25158336_k127_185420_0 1500897.JQNA01000002_gene4645 7.716e-104 366.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae 28216|Betaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3 SRR25158336_k127_185420_1 765910.MARPU_11235 2.995e-61 213.0 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1X2GB@135613|Chromatiales 135613|Chromatiales O Belongs to the glutathione peroxidase family - - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx SRR25158336_k127_196202_0 472759.Nhal_2538 3.327e-189 598.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1WW84@135613|Chromatiales 135613|Chromatiales E Vitamin B12 dependent methionine synthase activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans SRR25158336_k127_202278_3 316273.XCV1526 1.504e-38 147.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1X402@135614|Xanthomonadales 135614|Xanthomonadales L Hydrolase, TatD family yjjV - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SRR25158336_k127_202278_0 1123399.AQVE01000002_gene2331 2.616e-90 311.0 COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,462SE@72273|Thiotrichales 72273|Thiotrichales H ThiF family - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF SRR25158336_k127_202278_4 1123368.AUIS01000031_gene1415 1.732e-23 104.0 2ECQ3@1|root,31692@2|Bacteria,1PX3E@1224|Proteobacteria,1T8SY@1236|Gammaproteobacteria,2NDD8@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - SRR25158336_k127_202278_2 396588.Tgr7_2280 5.34e-39 148.0 COG2920@1|root,COG2920@2|Bacteria,1N6BU@1224|Proteobacteria,1S6FJ@1236|Gammaproteobacteria,1WYPC@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC SRR25158336_k127_202278_1 1123401.JHYQ01000002_gene2762 4.64e-54 194.0 COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,461AY@72273|Thiotrichales 72273|Thiotrichales S Copper resistance protein D - - - - - - - - - - - - CopD SRR25158336_k127_211578_2 396588.Tgr7_3257 7.231e-45 168.0 2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,1S4EG@1236|Gammaproteobacteria,1X1R5@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_211578_1 1026882.MAMP_01365 3.182e-168 532.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,4604S@72273|Thiotrichales 72273|Thiotrichales J glycyl-tRNA synthetase, alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e SRR25158336_k127_211578_0 519989.ECTPHS_01404 8.503e-237 753.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales 135613|Chromatiales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f SRR25158336_k127_211578_3 1049564.TevJSym_aq00120 2.247e-43 164.0 2F88A@1|root,340MG@2|Bacteria,1NXS1@1224|Proteobacteria,1SQ1P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - MazG SRR25158336_k127_211578_4 1286106.MPL1_09250 5.782e-33 131.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,460Q1@72273|Thiotrichales 72273|Thiotrichales E D,D-heptose 1,7-bisphosphate phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like SRR25158336_k127_212951_2 1121920.AUAU01000018_gene1790 1.939e-09 64.0 COG2353@1|root,COG2353@2|Bacteria,3Y4PV@57723|Acidobacteria 57723|Acidobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI SRR25158336_k127_212951_0 768671.ThimaDRAFT_1240 4.517e-91 303.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1WXB5@135613|Chromatiales 135613|Chromatiales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx SRR25158336_k127_212951_1 396588.Tgr7_0778 1e-59 212.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1WWMP@135613|Chromatiales 135613|Chromatiales M PFAM peptidase - - - - - - - - - - - - Peptidase_M23 SRR25158336_k127_222368_6 637390.AFOH01000106_gene108 5.168e-17 80.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,2NCNM@225057|Acidithiobacillales 225057|Acidithiobacillales C Transketolase, pyrimidine binding domain - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C SRR25158336_k127_222368_0 472759.Nhal_2782 0.0 1062.0 COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim SRR25158336_k127_222368_1 396588.Tgr7_2452 2.589e-226 704.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1WXPT@135613|Chromatiales 135613|Chromatiales E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth SRR25158336_k127_222368_5 1123401.JHYQ01000047_gene163 3.104e-61 213.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,460J9@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase SRR25158336_k127_222368_7 1122134.KB893650_gene1024 3.184e-12 72.0 2EB2G@1|root,33539@2|Bacteria,1NDPU@1224|Proteobacteria,1SDGR@1236|Gammaproteobacteria,1XQDW@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF3617) - - - - - - - - - - - - DUF3617 SRR25158336_k127_222368_4 2340.JV46_14240 8.906e-72 249.0 28Z54@1|root,2ZKXF@2|Bacteria,1RAVB@1224|Proteobacteria,1S46P@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - - SRR25158336_k127_222368_8 292415.Tbd_0447 4.832e-12 71.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,1KSBU@119069|Hydrogenophilales 119069|Hydrogenophilales S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase SRR25158336_k127_222368_2 1121374.KB891586_gene2776 2.508e-113 372.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - - - - - - - - - - DUF2437,FAA_hydrolase SRR25158336_k127_222368_3 857087.Metme_4094 8.814e-99 328.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XEP4@135618|Methylococcales 135618|Methylococcales M Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 SRR25158336_k127_241440_8 754477.Q7C_1794 5.463e-50 181.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,45ZP9@72273|Thiotrichales 72273|Thiotrichales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH SRR25158336_k127_241440_1 631362.Thi970DRAFT_00704 5.287e-215 675.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N SRR25158336_k127_241440_2 572477.Alvin_2078 3.347e-181 577.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR25158336_k127_241440_0 713586.KB900536_gene2226 5.482e-216 693.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 SRR25158336_k127_241440_10 314278.NB231_11619 1.503e-28 123.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 SRR25158336_k127_241440_3 472759.Nhal_3818 7.415e-142 462.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1WVWG@135613|Chromatiales 135613|Chromatiales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA - - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB SRR25158336_k127_241440_5 1049564.TevJSym_ag01040 2.372e-117 385.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1J4V0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048 Formyl_trans_C,Formyl_trans_N SRR25158336_k127_241440_7 1049564.TevJSym_ag01050 5.273e-74 254.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1J5V6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase SRR25158336_k127_241440_6 1026882.MAMP_00785 1.934e-106 356.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales 72273|Thiotrichales S Lysin motif - - - - - - - - - - - - LysM SRR25158336_k127_241440_4 105559.Nwat_3069 2.499e-121 400.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales 135613|Chromatiales LU TIGRFAM DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A SRR25158336_k127_241440_9 765914.ThisiDRAFT_1015 4.299e-47 173.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales 135613|Chromatiales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 SRR25158336_k127_244538_1 1168065.DOK_19075 4.255e-42 158.0 COG1914@1|root,COG1914@2|Bacteria 2|Bacteria P metal ion transmembrane transporter activity mntH - - - - - - - - - - - Nramp SRR25158336_k127_244538_0 1249627.D779_0035 3.137e-141 466.0 COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WW92@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,Response_reg SRR25158336_k127_248729_1 1283300.ATXB01000001_gene1395 5.089e-118 390.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1XDVR@135618|Methylococcales 135618|Methylococcales I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SRR25158336_k127_248729_0 472759.Nhal_0798 4.435e-320 993.0 COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1WWN6@135613|Chromatiales 135613|Chromatiales E Extracellular solute-binding protein, family 5 - - - - - - - - - - - - SBP_bac_5 SRR25158336_k127_249230_3 631362.Thi970DRAFT_00861 2.939e-34 132.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N SRR25158336_k127_249230_0 1049564.TevJSym_ai00300 2.643e-162 520.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1J4VW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretory pathway, component PulF pilC GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF SRR25158336_k127_249230_1 396588.Tgr7_0785 1.3e-115 379.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1WW7R@135613|Chromatiales 135613|Chromatiales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 SRR25158336_k127_249230_2 1190603.AJYD01000095_gene3583 2.635e-51 189.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XW2K@135623|Vibrionales 135623|Vibrionales F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE SRR25158336_k127_249230_4 472759.Nhal_3851 1.446e-21 103.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales 135613|Chromatiales D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD - - ko:K18778 - - - - ko00000,ko03036 - - - ZapD SRR25158336_k127_249312_2 1122139.KB907888_gene192 3.111e-08 57.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales 135619|Oceanospirillales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V SRR25158336_k127_249312_1 1033802.SSPSH_000074 1.176e-59 208.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - ko:K05524 - - - - ko00000 - - - DUF1971,DUF3470,Fer4 SRR25158336_k127_249312_0 713586.KB900536_gene37 8.919e-95 327.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria 1224|Proteobacteria L double-strand break repair protein AddB addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 SRR25158336_k127_252861_1 1202532.FF52_17898 1.7e-24 113.0 COG3637@1|root,COG3637@2|Bacteria,4NVQZ@976|Bacteroidetes,1IAJU@117743|Flavobacteriia,2NV9E@237|Flavobacterium 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - SRR25158336_k127_252861_0 1123070.KB899254_gene1181 5.336e-30 128.0 COG2067@1|root,COG2067@2|Bacteria,46X75@74201|Verrucomicrobia,2IUTY@203494|Verrucomicrobiae 203494|Verrucomicrobiae I long-chain fatty acid transport protein - - - - - - - - - - - - OMP_b-brl SRR25158336_k127_262097_4 1123368.AUIS01000005_gene430 1.025e-19 91.0 COG0235@1|root,COG0235@2|Bacteria,1N2XS@1224|Proteobacteria,1S573@1236|Gammaproteobacteria,2NCWS@225057|Acidithiobacillales 225057|Acidithiobacillales G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II SRR25158336_k127_262097_3 272123.Anacy_4556 3.513e-32 130.0 COG4446@1|root,COG4446@2|Bacteria,1G6W2@1117|Cyanobacteria,1HNRG@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 SRR25158336_k127_262097_2 519989.ECTPHS_10636 2.872e-37 146.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1WYJV@135613|Chromatiales 135613|Chromatiales M pfam nlp p60 - - - ko:K13695 - - - - ko00000,ko01002 - - - NLPC_P60 SRR25158336_k127_262097_1 1122134.KB893650_gene1234 8.112e-40 153.0 COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,1XK0G@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09906 - - - - ko00000,ko01000,ko03012 - - - EpmC SRR25158336_k127_262097_0 1177181.T9A_02729 2.768e-44 167.0 COG3295@1|root,COG3295@2|Bacteria,1RHV4@1224|Proteobacteria,1T5X1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM SRR25158336_k127_262559_2 717605.Theco_0502 3.71e-59 227.0 COG2755@1|root,COG4124@1|root,COG2755@2|Bacteria,COG4124@2|Bacteria,1UIB3@1239|Firmicutes,4HMW0@91061|Bacilli,277FZ@186822|Paenibacillaceae 91061|Bacilli E Pfam:DUF303 - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA SRR25158336_k127_262559_0 1172185.KB911518_gene2733 2.22e-70 242.0 COG2030@1|root,COG2030@2|Bacteria,2IK9K@201174|Actinobacteria,4G0UU@85025|Nocardiaceae 201174|Actinobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas SRR25158336_k127_262559_1 935840.JAEQ01000004_gene527 9.509e-61 216.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,43H2H@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Belongs to the HpcH HpaI aldolase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI SRR25158336_k127_262956_2 572477.Alvin_0250 1.6e-54 196.0 COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1WXVN@135613|Chromatiales 135613|Chromatiales G PfkB domain protein - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB SRR25158336_k127_262956_1 1116472.MGMO_87c00020 5.422e-87 298.0 COG0561@1|root,COG0561@2|Bacteria,1QDJR@1224|Proteobacteria,1RSEI@1236|Gammaproteobacteria,1XEIB@135618|Methylococcales 135618|Methylococcales S TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - - - - - - - - - - S6PP SRR25158336_k127_262956_0 768671.ThimaDRAFT_2890 1.787e-286 892.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,1MWVX@1224|Proteobacteria,1RSR5@1236|Gammaproteobacteria,1WWRD@135613|Chromatiales 135613|Chromatiales M HAD-superfamily hydrolase, subfamily IIB - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth SRR25158336_k127_263324_0 768671.ThimaDRAFT_2445 0.0 1118.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF SRR25158336_k127_263324_2 1286106.MPL1_07129 1.104e-14 84.0 2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,461FP@72273|Thiotrichales 72273|Thiotrichales S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV SRR25158336_k127_263324_1 105559.Nwat_2653 2.391e-45 167.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1WWNN@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine - - 2.4.2.28,2.4.2.44 ko:K00772,ko:K19696 ko00270,ko01100,map00270,map01100 M00034 R01402,R09668 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 SRR25158336_k127_263597_0 754476.Q7A_310 1.155e-159 518.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,45ZSQ@72273|Thiotrichales 72273|Thiotrichales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SRR25158336_k127_263597_2 768671.ThimaDRAFT_2244 2.545e-26 113.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1WYU8@135613|Chromatiales 135613|Chromatiales J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p SRR25158336_k127_263597_1 472759.Nhal_0072 9.179e-121 392.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA SRR25158336_k127_265082_1 1163617.SCD_n02349 1.865e-49 183.0 COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,1RHTS@1224|Proteobacteria,2VTRR@28216|Betaproteobacteria 28216|Betaproteobacteria CO Thioredoxin domain - - - - - - - - - - - - HEAT_2,Thioredoxin_3 SRR25158336_k127_265082_0 396595.TK90_0985 2.417e-229 729.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales 135613|Chromatiales P Sulfate transporter antisigma-factor antagonist STAS - - - - - - - - - - - - STAS,Sulfate_transp SRR25158336_k127_267904_2 1117647.M5M_13825 1.519e-58 211.0 COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,1RYI5@1236|Gammaproteobacteria,1J4XB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S membrane-bound metal-dependent hydrolases - - - ko:K07038 - - - - ko00000 - - - YdjM SRR25158336_k127_267904_0 396588.Tgr7_0025 1.006e-141 457.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 SRR25158336_k127_267904_1 243233.MCA0540 1.649e-76 264.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1S5KU@1236|Gammaproteobacteria,1XDYF@135618|Methylococcales 135618|Methylococcales GM NAD(P)H-binding - - - - - - - - - - - - Epimerase SRR25158336_k127_268701_4 870187.Thini_1111 9.285e-11 64.0 2DBMQ@1|root,2Z9ZP@2|Bacteria,1QVZU@1224|Proteobacteria,1T5C5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved TM helix - - - - - - - - - - - - TM_helix SRR25158336_k127_268701_0 443143.GM18_0341 4.277e-249 795.0 COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - - SRR25158336_k127_268701_5 377629.TERTU_3388 1.183e-09 72.0 COG4886@1|root,COG5640@1|root,COG4886@2|Bacteria,COG5640@2|Bacteria,1NFNT@1224|Proteobacteria,1S8XE@1236|Gammaproteobacteria,2PP1Q@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Trypsin-like serine protease - - - - - - - - - - - - TSP_3,Trypsin SRR25158336_k127_268701_2 870187.Thini_2003 8.214e-55 202.0 COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S alpha beta - - - - - - - - - - - - DUF3530 SRR25158336_k127_268701_1 686340.Metal_2066 1.163e-231 731.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XER8@135618|Methylococcales 135618|Methylococcales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C SRR25158336_k127_268701_3 1049564.TevJSym_aa01810 5.077e-14 73.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Citrate transporter sac1 - - - - - - - - - - - CitMHS,TrkA_C SRR25158336_k127_275045_5 1218352.B597_017300 3.655e-13 72.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNG@1236|Gammaproteobacteria,1Z02U@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg SRR25158336_k127_275045_1 1116472.MGMO_159c00020 9.731e-147 471.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the class I fructose-bisphosphate aldolase family alf1 - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic SRR25158336_k127_275045_4 1198232.CYCME_2013 7.978e-33 130.0 COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,1SE7J@1236|Gammaproteobacteria,463ER@72273|Thiotrichales 72273|Thiotrichales K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 SRR25158336_k127_275045_0 1198232.CYCME_2014 8.297e-149 477.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4605T@72273|Thiotrichales 72273|Thiotrichales O molecular chaperone - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C SRR25158336_k127_275045_2 626887.J057_16295 4.306e-131 436.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD SRR25158336_k127_275045_3 1278309.KB907102_gene218 1.751e-38 152.0 COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,1T2BY@1236|Gammaproteobacteria,1XKMM@135619|Oceanospirillales 135619|Oceanospirillales T Ion transport protein - - - - - - - - - - - - Ion_trans SRR25158336_k127_276372_3 240015.ACP_0692 1.824e-18 98.0 COG2303@1|root,COG2303@2|Bacteria 2|Bacteria E choline dehydrogenase activity - - - - - - - - - - - - DAO,GMC_oxred_C,GMC_oxred_N,NAD_binding_8,Pyr_redox_2 SRR25158336_k127_276372_2 756883.Halar_1947 3.108e-26 119.0 COG0702@1|root,arCOG03015@2157|Archaea 2157|Archaea GM NAD-dependent epimerase dehydratase nolA - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - NAD_binding_10 SRR25158336_k127_276372_0 1329516.JPST01000019_gene2718 1.975e-109 363.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,27CF0@186824|Thermoactinomycetaceae 91061|Bacilli M Glycosyltransferase like family 2 ykcC - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 SRR25158336_k127_276372_1 489825.LYNGBM3L_64070 1.096e-41 157.0 COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1H8D4@1150|Oscillatoriales 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SRR25158336_k127_27713_13 1461579.CCNK01000007_gene213 1.222e-21 96.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1Y6UY@135625|Pasteurellales 135625|Pasteurellales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N SRR25158336_k127_27713_11 243233.MCA2537 1.471e-44 167.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XEZ2@135618|Methylococcales 135618|Methylococcales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB SRR25158336_k127_27713_12 765913.ThidrDRAFT_2169 2.639e-33 133.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1WY0F@135613|Chromatiales 135613|Chromatiales P PFAM Rhodanese-like - - - - - - - - - - - - Rhodanese SRR25158336_k127_27713_9 1049564.TevJSym_at00250 1.559e-48 175.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1J7C4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor bigR - - - - - - - - - - - HTH_5 SRR25158336_k127_27713_0 1049564.TevJSym_at00260 7.743e-232 728.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N SRR25158336_k127_27713_6 1049564.TevJSym_at00270 1.144e-68 249.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1J4S5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG4942 Membrane-bound metallopeptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 SRR25158336_k127_27713_2 857087.Metme_0275 3.941e-181 579.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XEI9@135618|Methylococcales 135618|Methylococcales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 SRR25158336_k127_27713_8 247633.GP2143_17016 7.119e-57 207.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1J6T5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yibQ - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 SRR25158336_k127_27713_5 765911.Thivi_2784 4.002e-72 248.0 COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1WY2E@135613|Chromatiales 135613|Chromatiales S TIGRFAM DJ-1 family protein - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI SRR25158336_k127_27713_10 1123366.TH3_02105 5.179e-46 173.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UD20@28211|Alphaproteobacteria,2JU71@204441|Rhodospirillales 204441|Rhodospirillales M surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Rick_17kDa_Anti SRR25158336_k127_27713_7 1265503.KB905167_gene1737 4.432e-57 201.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria,2Q83G@267889|Colwelliaceae 1236|Gammaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2237) - - - ko:K09966 - - - - ko00000 - - - DUF2237 SRR25158336_k127_27713_1 396588.Tgr7_0285 5.157e-210 662.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1WXN7@135613|Chromatiales 135613|Chromatiales P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp SRR25158336_k127_27713_3 765910.MARPU_07815 1.065e-101 340.0 COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria,1WWHR@135613|Chromatiales 135613|Chromatiales I Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 SRR25158336_k127_27713_4 105559.Nwat_2191 8.612e-101 334.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 SRR25158336_k127_279008_1 1335757.SPICUR_04930 4.065e-104 341.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales 135613|Chromatiales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA SRR25158336_k127_279008_0 519989.ECTPHS_08558 0.0 1479.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon SRR25158336_k127_279008_2 56780.SYN_02005 1.055e-23 104.0 COG2199@1|root,COG3706@2|Bacteria,1RCC4@1224|Proteobacteria,43AED@68525|delta/epsilon subdivisions,2WQS7@28221|Deltaproteobacteria 1224|Proteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF SRR25158336_k127_281243_1 1049564.TevJSym_an00700 3.126e-110 389.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1J546@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria ytfN GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - ko:K09800 - - - - ko00000,ko02000 - - - TamB SRR25158336_k127_281243_0 323261.Noc_0370 2.346e-149 491.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1WWT6@135613|Chromatiales 135613|Chromatiales M Surface antigen variable number - - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 SRR25158336_k127_281243_2 1123401.JHYQ01000008_gene436 3.122e-15 78.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,1RZYP@1236|Gammaproteobacteria,461UJ@72273|Thiotrichales 72273|Thiotrichales P Domain of unknown function DUF21 - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 SRR25158336_k127_281810_1 396588.Tgr7_3279 2.666e-98 323.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1WW5T@135613|Chromatiales 135613|Chromatiales F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SRR25158336_k127_281810_0 1123279.ATUS01000001_gene2747 1.786e-170 542.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat SRR25158336_k127_284525_1 1026882.MAMP_00870 1.93e-187 595.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,45ZPU@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SRR25158336_k127_284525_2 105559.Nwat_0552 3.972e-106 351.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind SRR25158336_k127_284525_0 1249627.D779_0578 4.08e-286 884.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 SRR25158336_k127_284563_1 519989.ECTPHS_08266 4.082e-68 239.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1WXNU@135613|Chromatiales 135613|Chromatiales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin SRR25158336_k127_284563_0 519989.ECTPHS_08261 5.452e-146 468.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase SRR25158336_k127_288664_1 1049564.TevJSym_ao00430 1.818e-122 400.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1J4DF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Bifunctional purine biosynthesis protein PurH purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS SRR25158336_k127_288664_3 316275.VSAL_I2839 2.44e-18 91.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XXSR@135623|Vibrionales 135623|Vibrionales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 SRR25158336_k127_288664_0 1123368.AUIS01000015_gene2660 6.15e-145 466.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus SRR25158336_k127_288664_2 1123253.AUBD01000011_gene2092 2.845e-23 102.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1X70Z@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4 SRR25158336_k127_290011_1 472759.Nhal_3353 1.063e-116 379.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1WWIR@135613|Chromatiales 135613|Chromatiales H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SRR25158336_k127_290011_2 396588.Tgr7_2898 1.013e-60 218.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1WXDF@135613|Chromatiales 135613|Chromatiales J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA SRR25158336_k127_290011_3 1300345.LF41_459 7.47e-20 95.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X6S4@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis signal transduction protein - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW SRR25158336_k127_290011_0 519989.ECTPHS_03854 3.508e-121 397.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg SRR25158336_k127_295271_2 472759.Nhal_0455 1.818e-76 263.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1WW1J@135613|Chromatiales 135613|Chromatiales E PFAM peptidase M3A and M3B, thimet oligopeptidase F - - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 SRR25158336_k127_295271_3 1049564.TevJSym_ak00420 6.066e-68 236.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1J5UJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily yrdA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - - - - - - - - - - Hexapep SRR25158336_k127_295271_1 572477.Alvin_3065 5.415e-100 333.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1WW5V@135613|Chromatiales 135613|Chromatiales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N SRR25158336_k127_295271_0 765912.Thimo_0133 1.721e-169 537.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales 135613|Chromatiales H Belongs to the ALAD family - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD SRR25158336_k127_295271_4 314345.SPV1_13387 5.715e-53 191.0 COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria 1224|Proteobacteria S Bile acid sodium symporter - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF SRR25158336_k127_297658_1 335283.Neut_1770 1.204e-103 345.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,372VF@32003|Nitrosomonadales 28216|Betaproteobacteria C PFAM FAD dependent oxidoreductase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C SRR25158336_k127_297658_0 713586.KB900536_gene1974 9.531e-122 406.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1WVYB@135613|Chromatiales 135613|Chromatiales C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N SRR25158336_k127_29872_1 1212548.B381_08015 3.871e-94 316.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1Z0SJ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1304 GHMP_kinases_C,GHMP_kinases_N SRR25158336_k127_29872_2 1158756.AQXQ01000012_gene1807 3.744e-35 141.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1WZK9@135613|Chromatiales 135613|Chromatiales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB SRR25158336_k127_29872_0 713586.KB900536_gene1585 1.316e-107 369.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 SRR25158336_k127_299765_1 1158146.KB907132_gene38 6.729e-70 239.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 SRR25158336_k127_299765_0 349521.HCH_06193 4.998e-157 501.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L SRR25158336_k127_299765_2 1049564.TevJSym_aa00280 4.588e-09 57.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1J60B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L17 rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 SRR25158336_k127_312685_0 713586.KB900536_gene1379 4.981e-199 635.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase SRR25158336_k127_312685_1 105559.Nwat_0220 2.863e-10 62.0 COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SEN9@1236|Gammaproteobacteria,1X2MN@135613|Chromatiales 135613|Chromatiales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL SRR25158336_k127_312749_0 1123368.AUIS01000005_gene483 3.948e-124 406.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,2NBWP@225057|Acidithiobacillales 225057|Acidithiobacillales C 4Fe-4S dicluster domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7 SRR25158336_k127_312749_1 1049564.TevJSym_an00190 3.128e-97 327.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1J4NJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG2897 Rhodanese-related sulfurtransferase rhdA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese SRR25158336_k127_31768_0 1500894.JQNN01000001_gene1651 3.22e-98 332.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472RR@75682|Oxalobacteraceae 28216|Betaproteobacteria T PFAM EAL domain, GGDEF domain - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_3,PAS_4,Response_reg SRR25158336_k127_31768_1 2340.JV46_03610 1.259e-84 286.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1J56M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iYL1228.KPN_04440 Ala_racemase_C,Ala_racemase_N SRR25158336_k127_317858_1 1163617.SCD_n01515 4.194e-51 190.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria 28216|Betaproteobacteria Q PFAM Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD SRR25158336_k127_317858_0 1163617.SCD_n01514 9.477e-88 297.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria 28216|Betaproteobacteria Q Abc transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran SRR25158336_k127_317858_2 1163617.SCD_n01513 1.283e-47 174.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria 28216|Betaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS_2 SRR25158336_k127_321465_0 1255043.TVNIR_0569 1.184e-194 614.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1X0FJ@135613|Chromatiales 135613|Chromatiales P Sulfate permease family - - - - - - - - - - - - Sulfate_transp SRR25158336_k127_325813_0 519989.ECTPHS_00220 3.341e-281 876.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1WW6M@135613|Chromatiales 135613|Chromatiales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 SRR25158336_k127_325813_6 314278.NB231_06960 1.783e-39 156.0 COG2761@1|root,COG2761@2|Bacteria 2|Bacteria Q protein disulfide oxidoreductase activity - - - - - - - - - - - - DSBA SRR25158336_k127_325813_7 1026882.MAMP_02480 2.254e-30 124.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,460ZK@72273|Thiotrichales 72273|Thiotrichales J Belongs to the HSP15 family - - - ko:K04762 - - - - ko00000,ko03110 - - - S4 SRR25158336_k127_325813_5 768671.ThimaDRAFT_3437 1.1e-55 200.0 COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,1S56W@1236|Gammaproteobacteria,1WYDD@135613|Chromatiales 135613|Chromatiales F pfam nudix - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX SRR25158336_k127_325813_8 525897.Dbac_1947 1.799e-26 112.0 2CDNS@1|root,33GPE@2|Bacteria,1NJUN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_325813_4 580332.Slit_2280 8.783e-80 276.0 COG0240@1|root,COG0240@2|Bacteria,1RED0@1224|Proteobacteria,2W2AD@28216|Betaproteobacteria 28216|Betaproteobacteria I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase - - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N SRR25158336_k127_325813_1 1163617.SCD_n02930 4.994e-189 594.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria 28216|Betaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 SRR25158336_k127_325813_2 1163617.SCD_n02931 4.198e-162 520.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N SRR25158336_k127_325813_3 870187.Thini_2820 5.51e-108 353.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,460EA@72273|Thiotrichales 72273|Thiotrichales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid SRR25158336_k127_325822_2 396588.Tgr7_0108 3.192e-93 310.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1WWYM@135613|Chromatiales 135613|Chromatiales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran SRR25158336_k127_325822_4 105559.Nwat_3053 1.974e-29 120.0 COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales 135613|Chromatiales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE SRR25158336_k127_325822_5 391615.ABSJ01000038_gene406 2.161e-18 97.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SBFE@1236|Gammaproteobacteria,1J6Y2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Pfam Transposase IS66 - - - - - - - - - - - - - SRR25158336_k127_325822_1 2340.JV46_16840 3.66e-147 470.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1J5E4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K00930,ko:K22478 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255 AA_kinase,NAT SRR25158336_k127_325822_0 1116472.MGMO_125c00200 9.563e-192 628.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XDTR@135618|Methylococcales 135618|Methylococcales G alpha beta alpha domain I - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SRR25158336_k127_325822_3 1122201.AUAZ01000016_gene129 3.936e-31 122.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,466EZ@72275|Alteromonadaceae 1236|Gammaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase SRR25158336_k127_326619_1 319224.Sputcn32_3228 9.392e-06 54.0 2E9KN@1|root,333TE@2|Bacteria,1NCTP@1224|Proteobacteria,1SFMQ@1236|Gammaproteobacteria,2QCVA@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_326619_0 472759.Nhal_3769 3.395e-220 693.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWI3@135613|Chromatiales 135613|Chromatiales L PFAM UvrD REP helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C SRR25158336_k127_332622_0 290397.Adeh_3200 1.785e-23 114.0 COG3303@1|root,COG3303@2|Bacteria,1NT38@1224|Proteobacteria,43CCP@68525|delta/epsilon subdivisions,2X7NK@28221|Deltaproteobacteria,2YZY2@29|Myxococcales 28221|Deltaproteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - - SRR25158336_k127_336986_0 519989.ECTPHS_03919 1.511e-154 494.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1WWU0@135613|Chromatiales 135613|Chromatiales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N SRR25158336_k127_336986_2 713586.KB900536_gene1702 1.712e-72 248.0 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1WXPI@135613|Chromatiales 135613|Chromatiales F phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran SRR25158336_k127_336986_4 187272.Mlg_0348 4.707e-37 144.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1WYAH@135613|Chromatiales 135613|Chromatiales L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX SRR25158336_k127_336986_1 1049564.TevJSym_bn00100 3.716e-75 257.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1J62V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the UPF0301 (AlgH) family yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 SRR25158336_k127_336986_3 1049564.TevJSym_bn00090 9.777e-57 208.0 COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,1RQAX@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Periplasmic protein TonB links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C SRR25158336_k127_337461_0 1411685.U062_01730 1.446e-201 635.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J53P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp SRR25158336_k127_337461_1 930169.B5T_04184 2.003e-56 198.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XJH4@135619|Oceanospirillales 135619|Oceanospirillales K at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) glnK-2 - - ko:K04752 - - - - ko00000 - - - P-II SRR25158336_k127_341508_0 572477.Alvin_1592 0.0 1146.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales 135613|Chromatiales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 SRR25158336_k127_343255_2 396588.Tgr7_2629 1.157e-75 258.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE SRR25158336_k127_343255_3 1049564.TevJSym_bq00040 1.333e-63 229.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1J6E5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind SRR25158336_k127_343255_1 754477.Q7C_1108 1.053e-89 300.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales 72273|Thiotrichales C Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr SRR25158336_k127_343255_0 1479237.JMLY01000001_gene1972 1.766e-105 346.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,465DF@72275|Alteromonadaceae 1236|Gammaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD SRR25158336_k127_343255_4 1286106.MPL1_09010 2.732e-08 60.0 COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,461CR@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - SRR25158336_k127_343692_0 1123368.AUIS01000019_gene1224 1.512e-202 644.0 COG0569@1|root,COG1226@1|root,COG0569@2|Bacteria,COG1226@2|Bacteria,1R3QQ@1224|Proteobacteria,1RPFS@1236|Gammaproteobacteria,2NC05@225057|Acidithiobacillales 225057|Acidithiobacillales P Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N SRR25158336_k127_343692_2 1123368.AUIS01000019_gene1223 1.374e-54 195.0 2AHT8@1|root,3185S@2|Bacteria,1RH98@1224|Proteobacteria,1S7UG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_343692_1 472759.Nhal_2574 3.394e-124 405.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1WWNT@135613|Chromatiales 135613|Chromatiales S Metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 SRR25158336_k127_343692_4 472759.Nhal_2575 5.567e-34 136.0 COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,1SASF@1236|Gammaproteobacteria,1WZ0R@135613|Chromatiales 135613|Chromatiales I CDP-archaeol synthase - - 2.7.7.67 ko:K19664 ko00564,map00564 - R08966 RC00002 ko00000,ko00001,ko01000 - - - CarS-like SRR25158336_k127_343692_5 2340.JV46_06840 2.143e-09 63.0 2CCFS@1|root,2ZK5K@2|Bacteria,1P8AI@1224|Proteobacteria 2340.JV46_06840|- - - - - - - - - - - - - - - - SRR25158336_k127_343692_3 1049564.TevJSym_aj00780 5.437e-54 196.0 COG1075@1|root,COG1075@2|Bacteria,1NXDT@1224|Proteobacteria,1SQ0B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PGAP1-like protein - - - - - - - - - - - - PGAP1 SRR25158336_k127_345519_0 1397528.Q671_08410 8.892e-69 238.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XJ5P@135619|Oceanospirillales 135619|Oceanospirillales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin SRR25158336_k127_345519_2 519989.ECTPHS_04244 1.21e-25 110.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales 135613|Chromatiales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 SRR25158336_k127_345519_1 396588.Tgr7_3185 2.748e-47 174.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS SRR25158336_k127_345798_2 1085623.GNIT_3309 3.435e-42 156.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,464MH@72275|Alteromonadaceae 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 SRR25158336_k127_345798_1 1415778.JQMM01000001_gene423 6.137e-98 323.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1J6S4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 SRR25158336_k127_345798_0 1415778.JQMM01000001_gene424 3.883e-257 795.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1J53B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Aminotransferase hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 SRR25158336_k127_34642_1 765911.Thivi_4178 3.16e-156 498.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1WWSB@135613|Chromatiales 135613|Chromatiales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N SRR25158336_k127_34642_2 2340.JV46_16220 2.494e-74 256.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1J5QI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C SRR25158336_k127_34642_3 1123518.ARWI01000001_gene922 2.911e-71 245.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,460KW@72273|Thiotrichales 72273|Thiotrichales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro SRR25158336_k127_34642_0 1123517.JOMR01000001_gene1638 1.039e-168 536.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,45ZRA@72273|Thiotrichales 72273|Thiotrichales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C SRR25158336_k127_351237_0 1123368.AUIS01000005_gene447 6.02e-84 289.0 COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales 225057|Acidithiobacillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA SRR25158336_k127_351237_1 1296416.JACB01000036_gene2829 8.227e-16 85.0 COG2303@1|root,COG2303@2|Bacteria,4PH1X@976|Bacteroidetes,1IMAH@117743|Flavobacteriia,2YJ6R@290174|Aquimarina 976|Bacteroidetes E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - - - - - - - - - - - SRR25158336_k127_352322_2 2340.JV46_15480 8.373e-37 142.0 COG2168@1|root,COG2168@2|Bacteria 2|Bacteria P tRNA wobble position uridine thiolation tusB GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07237 ko04122,map04122 - - - ko00000,ko00001,ko03016 - - - DsrH SRR25158336_k127_352322_1 713587.THITH_12005 2.548e-57 205.0 COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1WYFA@135613|Chromatiales 135613|Chromatiales P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC SRR25158336_k127_352322_0 1163617.SCD_n02712 4.678e-109 357.0 COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria 28216|Betaproteobacteria C Nitrate reductase gamma subunit - - - - - - - - - - - - Nitrate_red_gam SRR25158336_k127_352322_3 713586.KB900536_gene1018 2.397e-25 106.0 COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales 135613|Chromatiales C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_17,Fer4_8 SRR25158336_k127_353628_1 1500893.JQNB01000001_gene6 2.335e-96 343.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg SRR25158336_k127_353628_0 396588.Tgr7_2901 7.753e-149 490.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X29W@135613|Chromatiales 135613|Chromatiales NT chemotaxis - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ SRR25158336_k127_358477_0 1323663.AROI01000009_gene3504 5.772e-151 494.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component ybbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX SRR25158336_k127_358477_1 1215092.PA6_007_01250 2.218e-87 295.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1YE00@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q ATPases associated with a variety of cellular activities ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SRR25158336_k127_358477_2 472759.Nhal_2580 2.146e-24 109.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1WY36@135613|Chromatiales 135613|Chromatiales E PFAM lipolytic protein G-D-S-L family - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 SRR25158336_k127_363055_3 396588.Tgr7_0852 1.771e-32 134.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1WYKN@135613|Chromatiales 135613|Chromatiales L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N SRR25158336_k127_363055_1 2340.JV46_04210 3.425e-52 186.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1J65P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 SRR25158336_k127_363055_0 425104.Ssed_1161 2.89e-99 329.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,2Q9QQ@267890|Shewanellaceae 1236|Gammaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT SRR25158336_k127_363055_2 1049564.TevJSym_aa01670 1.386e-44 164.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1J6R6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM SRR25158336_k127_365032_0 713587.THITH_07575 3.757e-265 828.0 28HY3@1|root,2Z83I@2|Bacteria,1R5P3@1224|Proteobacteria,1S1M3@1236|Gammaproteobacteria,1X028@135613|Chromatiales 135613|Chromatiales S phosphoenolpyruvate carboxykinase (diphosphate) activity - - 4.1.1.38 ko:K20370 ko00620,ko01100,map00620,map01100 - R00346 RC02741 ko00000,ko00001,ko01000 - - - - SRR25158336_k127_365032_3 930169.B5T_01148 1.599e-18 87.0 2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_365032_2 1415778.JQMM01000001_gene1373 1.458e-44 165.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1J66X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG1186 Protein chain release factor B yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 SRR25158336_k127_365032_1 519989.ECTPHS_11707 3.158e-60 211.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1WZ4B@135613|Chromatiales 135613|Chromatiales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N SRR25158336_k127_365675_2 686340.Metal_2681 6.818e-172 556.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,1XEBV@135618|Methylococcales 135618|Methylococcales EGP PFAM Major Facilitator Superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 SRR25158336_k127_365675_5 187272.Mlg_0337 3.755e-80 273.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,1X0N9@135613|Chromatiales 135613|Chromatiales Q Methionine biosynthesis protein MetW - - - - - - - - - - - - MetW SRR25158336_k127_365675_1 1177179.A11A3_09215 5.069e-180 570.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales 135619|Oceanospirillales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 SRR25158336_k127_365675_6 1260251.SPISAL_01600 3.915e-51 189.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales 135613|Chromatiales S integral membrane protein - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT SRR25158336_k127_365675_4 1049564.TevJSym_am00190 4.219e-94 317.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1J5GD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_0282,ic_1306.c0493 F420_oxidored,P5CR_dimer SRR25158336_k127_365675_0 1245471.PCA10_02900 2.129e-183 579.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1YF6Q@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NU Type II/IV secretion system protein pilT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SRR25158336_k127_365675_3 935863.AWZR01000007_gene154 3.901e-166 529.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1X4F6@135614|Xanthomonadales 135614|Xanthomonadales NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE SRR25158336_k127_373309_1 713586.KB900536_gene187 6.067e-83 286.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1WW4C@135613|Chromatiales 135613|Chromatiales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase SRR25158336_k127_373309_3 1255043.TVNIR_0815 2.155e-36 140.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1WZT2@135613|Chromatiales 135613|Chromatiales H Pterin 4 alpha carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a SRR25158336_k127_373309_4 768671.ThimaDRAFT_3772 9.342e-22 97.0 COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SF76@1236|Gammaproteobacteria,1WZJF@135613|Chromatiales 135613|Chromatiales C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 SRR25158336_k127_373309_0 1123401.JHYQ01000013_gene627 3.182e-154 497.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales 72273|Thiotrichales O PFAM Peptidase family M48 - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N SRR25158336_k127_373309_2 1026882.MAMP_01660 4.607e-72 246.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,460FA@72273|Thiotrichales 72273|Thiotrichales L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn - - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T SRR25158336_k127_37623_0 292415.Tbd_2056 6.861e-141 452.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria 28216|Betaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase SRR25158336_k127_37623_1 391625.PPSIR1_39470 5.224e-70 241.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,430WU@68525|delta/epsilon subdivisions,2WW29@28221|Deltaproteobacteria 28221|Deltaproteobacteria J RNA pseudouridylate synthase - - - - - - - - - - - - PseudoU_synth_2 SRR25158336_k127_37623_5 1121918.ARWE01000001_gene2703 0.0001134 46.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH SRR25158336_k127_37623_2 90814.KL370891_gene929 8.579e-49 178.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria 1236|Gammaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SRR25158336_k127_383234_1 105559.Nwat_0574 6.951e-09 56.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P SRR25158336_k127_383234_0 395493.BegalDRAFT_3524 1.15e-148 475.0 COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,460BF@72273|Thiotrichales 72273|Thiotrichales G PFAM pfkB family carbohydrate kinase - - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB SRR25158336_k127_384926_0 2340.JV46_15090 5.801e-216 674.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1J4X6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Adenylsucc_synt SRR25158336_k127_384926_1 713586.KB900536_gene2963 2.521e-100 335.0 COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,1WVUR@135613|Chromatiales 135613|Chromatiales E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His SRR25158336_k127_386817_7 713586.KB900536_gene391 2.447e-17 83.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WY2N@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 SRR25158336_k127_386817_1 1127673.GLIP_2511 1.22e-216 677.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,4647T@72275|Alteromonadaceae 1236|Gammaproteobacteria E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 SRR25158336_k127_386817_3 396588.Tgr7_2057 1.059e-52 186.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1WYM7@135613|Chromatiales 135613|Chromatiales S Belongs to the HesB IscA family - - - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SRR25158336_k127_386817_5 2340.JV46_04100 1.548e-34 139.0 COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1J6NP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA hscB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04082 - - - - ko00000,ko03029,ko03110 - - - DnaJ,HSCB_C SRR25158336_k127_386817_0 1049564.TevJSym_au00160 1.559e-276 862.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 SRR25158336_k127_386817_2 1158182.KB905020_gene2151 3.3e-62 215.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1X16T@135613|Chromatiales 135613|Chromatiales C 2Fe-2S iron-sulfur cluster binding domain - - - ko:K04755 - - - - ko00000 - - - Fer2 SRR25158336_k127_386817_6 1027273.GZ77_04175 9.122e-29 116.0 COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,1XMAV@135619|Oceanospirillales 135619|Oceanospirillales S Iron-sulphur cluster assembly - - - - - - - - - - - - Fe-S_assembly SRR25158336_k127_386817_4 243233.MCA1739 1.264e-51 188.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,1RNEJ@1236|Gammaproteobacteria,1XDRX@135618|Methylococcales 135618|Methylococcales G Belongs to the HpcH HpaI aldolase family - - 4.1.3.24,4.1.3.25,4.1.3.34 ko:K01644,ko:K08691 ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020 M00346,M00373,M00376 R00237,R00362,R00473,R00934 RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205 ko00000,ko00001,ko00002,ko01000 - - - HpcH_HpaI SRR25158336_k127_390534_5 1266914.ATUK01000001_gene799 5.482e-23 104.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1SASJ@1236|Gammaproteobacteria,1WY3C@135613|Chromatiales 135613|Chromatiales S Smr protein MutS2 - - - - - - - - - - - - Smr SRR25158336_k127_390534_1 396588.Tgr7_1432 5.04e-113 369.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales 135613|Chromatiales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE SRR25158336_k127_390534_3 1288826.MSNKSG1_04026 1.763e-73 253.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,465SD@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT SRR25158336_k127_390534_2 1049564.TevJSym_au00600 9.966e-74 253.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,1J6R2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SNARE associated Golgi protein Z012_09465 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc SRR25158336_k127_390534_4 1397527.Q670_09685 1.585e-58 214.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XJ9X@135619|Oceanospirillales 135619|Oceanospirillales DM COG0739 Membrane proteins related to metalloendopeptidases nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 SRR25158336_k127_390534_0 1049564.TevJSym_au00620 1.644e-122 399.0 COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1J4VY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG0568 DNA-directed RNA polymerase, sigma subunit rpoS GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03087 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SRR25158336_k127_404117_4 246201.SM12261_1003 1.113e-15 76.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,2TNR2@28037|Streptococcus mitis 91061|Bacilli H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase SRR25158336_k127_404117_2 396595.TK90_2485 3.524e-37 142.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales 135613|Chromatiales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic SRR25158336_k127_404117_1 1121937.AUHJ01000013_gene822 2.338e-135 440.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 SRR25158336_k127_404117_3 1123257.AUFV01000026_gene9 2.851e-18 94.0 2DQ0C@1|root,33473@2|Bacteria,1NAM4@1224|Proteobacteria,1SCY6@1236|Gammaproteobacteria,1XB49@135614|Xanthomonadales 135614|Xanthomonadales S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 SRR25158336_k127_404117_0 754477.Q7C_791 2.539e-152 506.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales 72273|Thiotrichales M PFAM AsmA family - - - ko:K07289 - - - - ko00000 - - - AsmA SRR25158336_k127_404209_3 697282.Mettu_2578 6.44e-10 61.0 COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria,1XFW4@135618|Methylococcales 135618|Methylococcales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - - CcmD SRR25158336_k127_404209_0 686340.Metal_1019 8.993e-119 385.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1XDXU@135618|Methylococcales 135618|Methylococcales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm SRR25158336_k127_404209_1 1049564.TevJSym_ad01700 6.846e-88 299.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,1J5R7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECO111_1330.ECO111_2936,iYL1228.KPN_02080 CcmB SRR25158336_k127_404209_2 1049564.TevJSym_ad01710 1.034e-73 253.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1J6FA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479 ABC_tran SRR25158336_k127_40459_1 545264.KB898751_gene2524 3.198e-62 217.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1WYBE@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 SRR25158336_k127_40459_3 1177179.A11A3_14622 1.298e-29 119.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales 135619|Oceanospirillales K cold-shock protein cspG - - ko:K03704 - - - - ko00000,ko03000 - - - CSD SRR25158336_k127_40459_2 1049564.TevJSym_ap00240 9.673e-36 137.0 2C7FC@1|root,32S1T@2|Bacteria,1N1DJ@1224|Proteobacteria,1S96F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_40459_0 2340.JV46_17250 9.128e-258 802.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1J4WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG0514 Superfamily II DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind SRR25158336_k127_408744_2 1049564.TevJSym_al00240 5.528e-15 82.0 2EN7Y@1|root,33FVR@2|Bacteria,1NHR8@1224|Proteobacteria,1SH6M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_408744_0 713587.THITH_07555 7.142e-70 244.0 COG0457@1|root,COG0457@2|Bacteria,1R85G@1224|Proteobacteria,1S0MD@1236|Gammaproteobacteria,1WXM8@135613|Chromatiales 135613|Chromatiales S Tetratricopeptide repeat - - - - - - - - - - - - - SRR25158336_k127_408744_1 1163617.SCD_n01885 1.297e-19 89.0 COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria 28216|Betaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 SRR25158336_k127_415408_2 713586.KB900536_gene1019 4.633e-50 179.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales 135613|Chromatiales C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2 SRR25158336_k127_415408_3 1123400.KB904780_gene1910 9.971e-31 130.0 2E6CU@1|root,3310G@2|Bacteria,1NBK1@1224|Proteobacteria,1S5EP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - dsrJ - - - - - - - - - - - - SRR25158336_k127_415408_1 1163617.SCD_n02708 9.899e-108 357.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11 SRR25158336_k127_415408_0 412965.COSY_0784 1.873e-133 432.0 COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1SMKH@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD SRR25158336_k127_427772_1 1121374.KB891575_gene1613 3.403e-21 96.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA SRR25158336_k127_427772_2 314278.NB231_13191 2.026e-13 73.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SX58@1236|Gammaproteobacteria,1WZBH@135613|Chromatiales 135613|Chromatiales S TIGRFAM TIGR02449 family protein - - - ko:K09892 - - - - ko00000,ko03036 - - - - SRR25158336_k127_427772_0 396588.Tgr7_2764 2.411e-143 462.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales 135613|Chromatiales E peptidase M24B, X-Pro dipeptidase aminopeptidase - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 SRR25158336_k127_431561_0 1026882.MAMP_01282 7.897e-189 594.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RWC8@1236|Gammaproteobacteria,460AJ@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - LeuA_dimer,PALP SRR25158336_k127_431561_1 713586.KB900536_gene342 7.875e-119 385.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1WWHB@135613|Chromatiales 135613|Chromatiales E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 SRR25158336_k127_440193_2 1122134.KB893650_gene790 5.923e-21 93.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB SRR25158336_k127_440193_1 105559.Nwat_0036 1.244e-43 164.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1WYX8@135613|Chromatiales 135613|Chromatiales H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK SRR25158336_k127_440193_0 396588.Tgr7_0329 1.743e-120 399.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,1WWJG@135613|Chromatiales 135613|Chromatiales S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 SRR25158336_k127_441362_2 472759.Nhal_3458 3.776e-23 103.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales 135613|Chromatiales Q PFAM methyltransferase - - - - - - - - - - - - Methyltransf_11 SRR25158336_k127_441362_1 1177179.A11A3_06710 4.976e-70 240.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H SRR25158336_k127_441362_0 1049564.TevJSym_au00460 2.195e-93 312.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1J4T2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 ko:K02342,ko:K14159 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_H,RNase_T SRR25158336_k127_441362_5 1121921.KB898709_gene239 0.0001808 48.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,2PNMA@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria P Citrate transporter nhaD - - - - - - - - - - - CitMHS SRR25158336_k127_441362_4 177439.DP2086 5.053e-09 57.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2WKSV@28221|Deltaproteobacteria,2MHUQ@213118|Desulfobacterales 28221|Deltaproteobacteria P Na H antiporter - - - - - - - - - - - - CitMHS,PAS SRR25158336_k127_441362_3 314285.KT71_04495 1.96e-13 79.0 2DSEK@1|root,33FUB@2|Bacteria,1NI40@1224|Proteobacteria,1SJE3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4082) - - - - - - - - - - - - DUF4082,VPEP SRR25158336_k127_442265_0 1026882.MAMP_01646 5.943e-249 785.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4604W@72273|Thiotrichales 72273|Thiotrichales D cell division protein ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma SRR25158336_k127_442265_1 396588.Tgr7_2005 1.873e-129 427.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1WXVZ@135613|Chromatiales 135613|Chromatiales C Belongs to the AlaDH PNT family - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N SRR25158336_k127_442265_2 765910.MARPU_11570 2.867e-46 168.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales 135613|Chromatiales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SRR25158336_k127_444655_4 1207076.ALAT01000147_gene413 2.491e-30 125.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1Z1Q8@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NU COG3170 Tfp pilus assembly protein FimV fimV - - ko:K08086 - - - - ko00000 - - - LysM,TPR_19 SRR25158336_k127_444655_0 519989.ECTPHS_11110 5.82e-181 570.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC SRR25158336_k127_444655_5 686578.AFFX01000001_gene1113 5.333e-29 117.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082 Iso_dh SRR25158336_k127_444655_1 243233.MCA2063 1.069e-128 415.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XDQR@135618|Methylococcales 135618|Methylococcales H Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SRR25158336_k127_444655_2 1121035.AUCH01000014_gene2418 9.915e-101 332.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KUET@206389|Rhodocyclales 206389|Rhodocyclales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C SRR25158336_k127_444655_3 1123393.KB891316_gene1199 1.318e-49 177.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,1KS35@119069|Hydrogenophilales 119069|Hydrogenophilales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase SRR25158336_k127_445302_1 8083.ENSXMAP00000007809 2.697e-07 63.0 2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,4834K@7711|Chordata,48UZ9@7742|Vertebrata,49W7A@7898|Actinopterygii 33208|Metazoa W Thrombospondin 1b THBS1 GO:0000187,GO:0000302,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001786,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001937,GO:0001944,GO:0001952,GO:0001953,GO:0001968,GO:0002040,GO:0002376,GO:0002544,GO:0002576,GO:0002577,GO:0002578,GO:0002580,GO:0002581,GO:0002604,GO:0002605,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003007,GO:0003151,GO:0003197,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005543,GO:0005575,GO:0005576,GO:0005577,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006417,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006911,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007049,GO:0007050,GO:0007155,GO:0007162,GO:0007275,GO:0007507,GO:0007610,GO:0008150,GO:0008152,GO:0008201,GO:0008284,GO:0008285,GO:0008289,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010324,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010596,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010746,GO:0010748,GO:0010749,GO:0010751,GO:0010752,GO:0010754,GO:0010755,GO:0010757,GO:0010758,GO:0010759,GO:0010762,GO:0010763,GO:0010810,GO:0010811,GO:0010812,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0017015,GO:0017134,GO:0018149,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0022402,GO:0022603,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030155,GO:0030162,GO:0030169,GO:0030193,GO:0030194,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030511,GO:0031012,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032026,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032570,GO:0032655,GO:0032680,GO:0032695,GO:0032760,GO:0032879,GO:0032890,GO:0032891,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033554,GO:0033555,GO:0033674,GO:0033993,GO:0034248,GO:0034250,GO:0034284,GO:0034599,GO:0034605,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0034774,GO:0034976,GO:0035239,GO:0035265,GO:0035295,GO:0035690,GO:0036211,GO:0036293,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040036,GO:0040037,GO:0042035,GO:0042108,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042534,GO:0042535,GO:0042802,GO:0042981,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043236,GO:0043269,GO:0043271,GO:0043277,GO:0043281,GO:0043394,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043535,GO:0043536,GO:0043537,GO:0043549,GO:0043652,GO:0044070,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045765,GO:0045766,GO:0045785,GO:0045786,GO:0045859,GO:0045860,GO:0045861,GO:0045937,GO:0046872,GO:0046903,GO:0048265,GO:0048266,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048660,GO:0048661,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051049,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051592,GO:0051674,GO:0051716,GO:0051726,GO:0051893,GO:0051895,GO:0051896,GO:0051897,GO:0051917,GO:0051918,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0060548,GO:0061024,GO:0061041,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070051,GO:0070052,GO:0070482,GO:0070613,GO:0070887,GO:0071241,GO:0071622,GO:0071634,GO:0071636,GO:0071675,GO:0071704,GO:0071731,GO:0071732,GO:0071813,GO:0071814,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072341,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090109,GO:0090287,GO:0090288,GO:0090303,GO:0097366,GO:0097367,GO:0097708,GO:0098552,GO:0098657,GO:0098868,GO:0099024,GO:0099503,GO:1900046,GO:1900048,GO:1901342,GO:1901343,GO:1901564,GO:1901654,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1902041,GO:1902043,GO:1902170,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903317,GO:1903318,GO:1903391,GO:1903392,GO:1903555,GO:1903557,GO:1903587,GO:1903588,GO:1903670,GO:1903671,GO:1903706,GO:1903792,GO:1903844,GO:1903846,GO:1903959,GO:1903960,GO:1904018,GO:1904035,GO:1904037,GO:1905521,GO:1905523,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000191,GO:2000192,GO:2000351,GO:2000353,GO:2000377,GO:2000379,GO:2001026,GO:2001027,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238 - ko:K04659,ko:K16857 ko04015,ko04115,ko04145,ko04151,ko04350,ko04510,ko04512,ko05144,ko05165,ko05205,ko05206,ko05219,map04015,map04115,map04145,map04151,map04350,map04510,map04512,map05144,map05165,map05205,map05206,map05219 - - - ko00000,ko00001,ko00536,ko04131,ko04147,ko04516 - - - EGF_3,EGF_CA,Laminin_G_2,TSP_1,TSP_3,TSP_C,VWC SRR25158336_k127_445302_0 448385.sce0202 3.638e-74 267.0 COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R66T@1224|Proteobacteria 1224|Proteobacteria C amine dehydrogenase activity - - - - - - - - - - - - - SRR25158336_k127_446131_4 479434.Sthe_1707 6.846e-17 87.0 COG5652@1|root,COG5652@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - VanZ SRR25158336_k127_446131_0 933262.AXAM01000048_gene2575 1.002e-124 408.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,42N94@68525|delta/epsilon subdivisions,2WJH4@28221|Deltaproteobacteria,2MHUN@213118|Desulfobacterales 28221|Deltaproteobacteria M Polysaccharide biosynthesis protein galE - 5.1.3.2,5.1.3.5 ko:K01784,ko:K12448 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01473,R02984 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SRR25158336_k127_446131_2 1163617.SCD_n01330 3.336e-115 384.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria 28216|Betaproteobacteria U SMART AAA ATPase - - - - - - - - - - - - AAA_22 SRR25158336_k127_446131_3 1163617.SCD_n01329 6.118e-79 271.0 COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VN0C@28216|Betaproteobacteria 28216|Betaproteobacteria D Capsular exopolysaccharide family epsG - 2.7.10.1 ko:K08252,ko:K16692 - - - - ko00000,ko01000,ko01001 - - - AAA_31,CbiA,GNVR,Wzz SRR25158336_k127_446131_1 1163617.SCD_n01328 7.137e-118 394.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria 28216|Betaproteobacteria M Polysaccharide chain length determinant protein - - - - - - - - - - - - Wzz SRR25158336_k127_448635_0 1283300.ATXB01000001_gene42 4.931e-91 304.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RQMD@1236|Gammaproteobacteria,1XGZF@135618|Methylococcales 135618|Methylococcales G Carbohydrate phosphorylase - - - - - - - - - - - - Phosphorylase SRR25158336_k127_448635_1 686340.Metal_0373 1.26e-05 52.0 2AUTV@1|root,31KGX@2|Bacteria,1QIC2@1224|Proteobacteria,1TG6B@1236|Gammaproteobacteria,1XFSU@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF2934) - - - - - - - - - - - - DUF2934 SRR25158336_k127_454713_1 1385935.N836_11300 1.048e-67 237.0 COG1225@1|root,COG1225@2|Bacteria,1G3WF@1117|Cyanobacteria,1HAID@1150|Oscillatoriales 1117|Cyanobacteria O PFAM AhpC TSA family - - - - - - - - - - - - AhpC-TSA SRR25158336_k127_454713_2 1049564.TevJSym_ac01660 2.208e-45 171.0 COG1309@1|root,COG1309@2|Bacteria,1PH8D@1224|Proteobacteria,1RW67@1236|Gammaproteobacteria,1J77A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SRR25158336_k127_454713_0 1120999.JONM01000002_gene951 2.643e-70 243.0 COG0204@1|root,COG0204@2|Bacteria 2|Bacteria I Acyl-transferase cmk - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase,Cytidylate_kin SRR25158336_k127_455584_2 998674.ATTE01000001_gene1740 2.752e-64 222.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SRR25158336_k127_455584_4 1211114.ALIP01000034_gene1862 6.439e-24 103.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1X7C1@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC SRR25158336_k127_455584_1 1049564.TevJSym_au00530 2.288e-75 259.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1JA2U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2747,iBWG_1329.BWG_2483,iEC55989_1330.EC55989_3019,iECDH10B_1368.ECDH10B_2915,iECDH1ME8569_1439.ECDH1ME8569_2657,iECIAI1_1343.ECIAI1_2848,iECO103_1326.ECO103_3289,iECO111_1330.ECO111_3471,iECO26_1355.ECO26_3816,iECSE_1348.ECSE_2999,iECW_1372.ECW_m2953,iEKO11_1354.EKO11_1022,iEcDH1_1363.EcDH1_0941,iEcE24377_1341.EcE24377A_3048,iEcHS_1320.EcHS_A2885,iEcolC_1368.EcolC_0965,iJO1366.b2747,iJR904.b2747,iPC815.YPO3361,iSBO_1134.SBO_2773,iSDY_1059.SDY_2946,iSSON_1240.SSON_2895,iSbBS512_1146.SbBS512_E3127,iUMNK88_1353.UMNK88_3422,iWFL_1372.ECW_m2953,iY75_1357.Y75_RS14300 IspD SRR25158336_k127_455584_3 1266908.AQPB01000052_gene763 1.043e-58 210.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1WY23@135613|Chromatiales 135613|Chromatiales I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB SRR25158336_k127_455584_0 243233.MCA2519 1.186e-106 356.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XDYC@135618|Methylococcales 135618|Methylococcales J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD - 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD SRR25158336_k127_455584_5 1049564.TevJSym_au00570 1.033e-14 74.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1J64J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria smrA - - - - - - - - - - - Smr SRR25158336_k127_468848_1 582744.Msip34_0239 5.153e-90 298.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,2KKR5@206350|Nitrosomonadales 206350|Nitrosomonadales E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N SRR25158336_k127_468848_2 105559.Nwat_0389 9.528e-42 160.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1WYQ1@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, chi subunit - - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi SRR25158336_k127_468848_0 243233.MCA2097 6.953e-99 325.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XEJP@135618|Methylococcales 135618|Methylococcales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 SRR25158336_k127_470609_7 292415.Tbd_2446 1.716e-08 58.0 COG3193@1|root,COG3193@2|Bacteria,1RJ3X@1224|Proteobacteria,2WFMV@28216|Betaproteobacteria 28216|Betaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading SRR25158336_k127_470609_5 1123368.AUIS01000003_gene1844 4.264e-34 138.0 2C7AT@1|root,338A4@2|Bacteria,1NF74@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_470609_2 1123368.AUIS01000003_gene1845 2.961e-54 196.0 COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1S6Y0@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,LGT,Redoxin SRR25158336_k127_470609_6 396588.Tgr7_2545 1.516e-25 108.0 2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_470609_4 2340.JV46_19810 4.897e-40 154.0 COG2062@1|root,COG2062@2|Bacteria,1QBKZ@1224|Proteobacteria,1T76I@1236|Gammaproteobacteria,1J79Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Histidine phosphatase superfamily (branch 1) - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 SRR25158336_k127_470609_3 591158.SSMG_04281 7.894e-45 174.0 COG1073@1|root,COG1073@2|Bacteria,2IC0U@201174|Actinobacteria 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4 SRR25158336_k127_470609_1 1137799.GZ78_14230 2.706e-125 411.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,1RQBV@1236|Gammaproteobacteria,1XI5J@135619|Oceanospirillales 135619|Oceanospirillales M Domain of unknown function (DUF3524) - - - - - - - - - - - - DUF3524,Glyco_trans_1_4,Glycos_transf_1 SRR25158336_k127_470609_0 1283300.ATXB01000001_gene817 1.487e-131 426.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1XEM7@135618|Methylococcales 135618|Methylococcales E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 SRR25158336_k127_470780_6 754476.Q7A_2030 1.158e-12 76.0 2CI2R@1|root,2ZCPY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - NERD SRR25158336_k127_470780_3 2340.JV46_07070 1.411e-79 275.0 COG2159@1|root,COG2159@2|Bacteria,1R44U@1224|Proteobacteria,1S88Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S amidohydrolase - - - - - - - - - - - - Amidohydro_2 SRR25158336_k127_470780_5 887062.HGR_02188 3.293e-19 92.0 2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,4AEEU@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_470780_0 1131553.JIBI01000012_gene823 6.819e-151 489.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria,372K1@32003|Nitrosomonadales 28216|Betaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - NfeD SRR25158336_k127_470780_2 247633.GP2143_06160 3.79e-111 364.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1J4G1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs qmcA - - - - - - - - - - - Band_7 SRR25158336_k127_470780_1 1122604.JONR01000033_gene31 9.265e-123 399.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1X42V@135614|Xanthomonadales 135614|Xanthomonadales H polyphosphate kinase - - - - - - - - - - - - PPK2 SRR25158336_k127_470780_4 1492922.GY26_11115 2.026e-19 98.0 COG5607@1|root,COG5607@2|Bacteria,1Q6AS@1224|Proteobacteria,1T8T5@1236|Gammaproteobacteria,1JBGZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S CHAD - - - - - - - - - - - - CHAD SRR25158336_k127_472025_2 2340.JV46_17900 1.72e-21 94.0 COG1993@1|root,COG1993@2|Bacteria,1N8TP@1224|Proteobacteria,1SDYH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 SRR25158336_k127_472025_0 870187.Thini_0598 7.975e-197 621.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,45ZPQ@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b SRR25158336_k127_472025_3 517417.Cpar_0009 4.91e-15 79.0 COG2863@1|root,COG2863@2|Bacteria,1FE7R@1090|Chlorobi 1090|Chlorobi C PFAM cytochrome c, class I - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - - SRR25158336_k127_472025_1 1269813.ATUL01000010_gene528 2.122e-91 311.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1WXVR@135613|Chromatiales 135613|Chromatiales S Flavocytochrome c sulphide dehydrogenase, flavin-binding - - 1.8.2.3 ko:K17229 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001,ko01000 - - - FCSD-flav_bind,Pyr_redox_2,TAT_signal SRR25158336_k127_474526_2 1120953.AUBH01000010_gene161 4.72e-61 215.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,464NS@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase yihG - - - - - - - - - - - Acyltransferase SRR25158336_k127_474526_1 1123368.AUIS01000019_gene1213 1.987e-66 230.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales 225057|Acidithiobacillales C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 SRR25158336_k127_474526_0 1120966.AUBU01000008_gene2392 2.994e-83 283.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 SRR25158336_k127_476312_0 1288494.EBAPG3_27890 2.483e-112 375.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin SRR25158336_k127_476312_1 1283300.ATXB01000001_gene2403 1.797e-48 175.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,1XE3M@135618|Methylococcales 135618|Methylococcales S AAA-like domain - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 SRR25158336_k127_481009_1 314231.FP2506_01195 1.991e-53 205.0 COG3550@1|root,COG3550@2|Bacteria 2|Bacteria S kinase activity - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C SRR25158336_k127_481009_0 472759.Nhal_3098 1.031e-109 369.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Amino Acid - - - - - - - - - - - - AA_permease_2 SRR25158336_k127_487050_0 1123401.JHYQ01000028_gene3187 1.881e-89 303.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,460DD@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase SRR25158336_k127_487050_3 1255043.TVNIR_3015 3.671e-26 113.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1WYZ4@135613|Chromatiales 135613|Chromatiales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC SRR25158336_k127_487050_2 391615.ABSJ01000054_gene1403 2.371e-40 157.0 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1JAR0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC SRR25158336_k127_487050_1 396588.Tgr7_1236 9.231e-67 231.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS SRR25158336_k127_49726_0 1283300.ATXB01000001_gene817 1.536e-70 241.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1XEM7@135618|Methylococcales 135618|Methylococcales E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 SRR25158336_k127_49726_1 697282.Mettu_2975 6.022e-45 164.0 2CDMX@1|root,32S1K@2|Bacteria,1N1I8@1224|Proteobacteria,1S9N4@1236|Gammaproteobacteria,1XFN4@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - SRR25158336_k127_501110_2 1260251.SPISAL_05835 1.176e-15 78.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1WYBV@135613|Chromatiales 135613|Chromatiales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS SRR25158336_k127_501110_1 1123261.AXDW01000001_gene1409 1.502e-40 162.0 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1X6CK@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretion system protein C - - - - - - - - - - - - PDZ_2,T2SSC SRR25158336_k127_501110_0 1415780.JPOG01000001_gene1732 1.218e-59 214.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X4RY@135614|Xanthomonadales 135614|Xanthomonadales NU secretion system protein xcsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N SRR25158336_k127_505023_3 579405.Dd703_0667 4.966e-22 96.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,2JD3Q@204037|Dickeya 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N SRR25158336_k127_505023_1 396588.Tgr7_1124 2.957e-105 350.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_505023_0 1121374.KB891586_gene2538 5.298e-111 372.0 COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Sodium hydrogen exchanger - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger SRR25158336_k127_505023_2 1288826.MSNKSG1_14177 2.789e-87 300.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA SRR25158336_k127_506209_0 1123518.ARWI01000001_gene1764 8.534e-210 662.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,45ZZB@72273|Thiotrichales 72273|Thiotrichales P Cation transporter/ATPase, N-terminus - - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 SRR25158336_k127_507264_1 1049564.TevJSym_bc00300 9.384e-37 139.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1J9VF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Hydrogenase formation hypA family hypD GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - ko:K04654 - - - - ko00000 - - - HypD SRR25158336_k127_507264_0 2340.JV46_24300 3.527e-120 391.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria KO Hydrogenase accessory protein HypB hypB - - ko:K04652 - - - - ko00000,ko03110 - - - cobW SRR25158336_k127_507264_2 765914.ThisiDRAFT_1290 2.704e-35 140.0 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,1WYQN@135613|Chromatiales 135613|Chromatiales S Probably plays a role in a hydrogenase nickel cofactor insertion step hypA - - ko:K04651 - - - - ko00000,ko03110 - - - HypA SRR25158336_k127_507264_3 1049564.TevJSym_bc00330 1.328e-31 124.0 COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria 1236|Gammaproteobacteria O TIGRFAM hydrogenase assembly chaperone hypC hupF hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC SRR25158336_k127_50753_0 396588.Tgr7_0989 6.228e-259 800.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa SRR25158336_k127_50753_3 1121015.N789_01610 3.71e-83 283.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1X302@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa SRR25158336_k127_50753_2 375286.mma_1463 1.27e-99 325.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,473FT@75682|Oxalobacteraceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 SRR25158336_k127_50753_4 1236959.BAMT01000010_gene3264 2.3e-57 201.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KMXA@206350|Nitrosomonadales 206350|Nitrosomonadales C NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 - - - - - - - - - - - - Oxidored_q4 SRR25158336_k127_50753_5 1123400.KB904769_gene2810 2.284e-21 99.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,46176@72273|Thiotrichales 72273|Thiotrichales U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG SRR25158336_k127_50753_1 396588.Tgr7_0984 8.359e-103 340.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales 135613|Chromatiales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM SRR25158336_k127_50753_6 402626.Rpic_4746 8.194e-10 63.0 COG0463@1|root,COG0463@2|Bacteria,1P77I@1224|Proteobacteria,2VPIE@28216|Betaproteobacteria,1K3F3@119060|Burkholderiaceae 28216|Betaproteobacteria M glycosyl transferase - - - - - - - - - - - - Glycos_transf_2 SRR25158336_k127_514573_1 1049564.TevJSym_bl00210 4.487e-106 353.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1J4T1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT SRR25158336_k127_514573_0 713586.KB900536_gene2956 1.732e-144 466.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1WWKZ@135613|Chromatiales 135613|Chromatiales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C SRR25158336_k127_516849_4 118166.JH976537_gene2018 3.352e-25 106.0 COG0847@1|root,COG0847@2|Bacteria,1G66K@1117|Cyanobacteria,1HEXZ@1150|Oscillatoriales 1117|Cyanobacteria L EXOIII - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T SRR25158336_k127_516849_1 207954.MED92_15118 2.586e-45 169.0 COG1495@1|root,COG1495@2|Bacteria,1PSD8@1224|Proteobacteria,1TAIR@1236|Gammaproteobacteria,1XKDA@135619|Oceanospirillales 135619|Oceanospirillales O Disulfide bond formation protein DsbB - - - - - - - - - - - - DsbB SRR25158336_k127_516849_2 870187.Thini_3061 7.371e-43 163.0 COG3122@1|root,COG3122@2|Bacteria,1N15V@1224|Proteobacteria,1S5V0@1236|Gammaproteobacteria,46163@72273|Thiotrichales 72273|Thiotrichales S Uncharacterized protein conserved in bacteria (DUF2058) - - - ko:K09912 - - - - ko00000 - - - DUF2058 SRR25158336_k127_516849_0 1123514.KB905899_gene1275 2.263e-128 417.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,463X7@72273|Thiotrichales 72273|Thiotrichales G 6-phosphogluconate dehydrogenase, C-terminal domain - - - - - - - - - - - - 6PGD,NAD_binding_2 SRR25158336_k127_516849_3 1123514.KB905899_gene1276 5.802e-32 128.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,4607Q@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - - - - - - - - - - - G6PD_C,G6PD_N SRR25158336_k127_529904_2 1266908.AQPB01000058_gene2425 4.822e-34 137.0 COG3151@1|root,COG3151@2|Bacteria,1NAPI@1224|Proteobacteria,1SEY8@1236|Gammaproteobacteria,1WYT2@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1249) - - - ko:K09920 - - - - ko00000 - - - DUF1249 SRR25158336_k127_529904_0 1123368.AUIS01000005_gene485 2.4e-224 704.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,2NBSD@225057|Acidithiobacillales 225057|Acidithiobacillales C FAD linked oxidases, C-terminal domain - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 SRR25158336_k127_529904_1 1049564.TevJSym_aj00680 5.366e-119 394.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,1J5UK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases glcE GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - iETEC_1333.ETEC_3246 FAD-oxidase_C,FAD_binding_4 SRR25158336_k127_529904_3 519989.ECTPHS_05911 2.346e-28 119.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1WVW1@135613|Chromatiales 135613|Chromatiales C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 SRR25158336_k127_541381_2 378806.STAUR_4012 4.427e-39 155.0 COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,42SJT@68525|delta/epsilon subdivisions,2WP3F@28221|Deltaproteobacteria,2YURW@29|Myxococcales 28221|Deltaproteobacteria H Belongs to the P-Pant transferase superfamily - - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS SRR25158336_k127_541381_0 243233.MCA2977 7.092e-112 376.0 COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,1RMH4@1236|Gammaproteobacteria,1XDPA@135618|Methylococcales 135618|Methylococcales T Histidine kinase - - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c SRR25158336_k127_541381_1 243233.MCA2976 1.136e-71 246.0 COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,1S3PE@1236|Gammaproteobacteria,1XE1Z@135618|Methylococcales 135618|Methylococcales T response regulator - - - ko:K15012 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg SRR25158336_k127_541381_3 1236542.BALM01000014_gene1167 6.023e-09 57.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,2Q8PT@267890|Shewanellaceae 1236|Gammaproteobacteria L Belongs to the DnaA family hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA SRR25158336_k127_544265_0 754476.Q7A_1146 1.117e-256 807.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales 72273|Thiotrichales V ABC transporter transmembrane region - - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 SRR25158336_k127_544265_1 1122135.KB893138_gene1118 5.941e-17 86.0 2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,2UKAX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S tryptophan synthase subunit beta - - - - - - - - - - - - - SRR25158336_k127_544265_2 506534.Rhein_1553 8.306e-15 76.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1X2RW@135613|Chromatiales 135613|Chromatiales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF SRR25158336_k127_544977_2 243365.CV_0565 4.611e-11 67.0 COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2WE7J@28216|Betaproteobacteria,2KTVU@206351|Neisseriales 206351|Neisseriales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin SRR25158336_k127_544977_0 1049564.TevJSym_bt00170 3.596e-143 467.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1J4EF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1519 3-deoxy-D-manno-octulosonic-acid transferase waaA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417 Glycos_transf_1,Glycos_transf_N SRR25158336_k127_544977_1 32042.PstZobell_19893 3.744e-52 189.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1Z03P@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans SRR25158336_k127_547173_0 555088.DealDRAFT_0493 9.714e-108 358.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia 186801|Clostridia P TIGRFAM anion transporter - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp SRR25158336_k127_548535_2 187272.Mlg_1805 1.161e-43 162.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1WWPU@135613|Chromatiales 135613|Chromatiales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR25158336_k127_548535_0 396588.Tgr7_1460 7.91e-218 689.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1WW9D@135613|Chromatiales 135613|Chromatiales L single-stranded-DNA-specific exonuclease RecJ - - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 SRR25158336_k127_548535_1 768671.ThimaDRAFT_2017 6.714e-46 175.0 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1S23W@1236|Gammaproteobacteria,1WY5V@135613|Chromatiales 135613|Chromatiales S protein conserved in bacteria - - - - - - - - - - - - - SRR25158336_k127_552064_1 105559.Nwat_2718 1.079e-61 216.0 COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722,DUF523 SRR25158336_k127_552064_4 255470.cbdbA953 9.52e-21 99.0 COG2928@1|root,COG2928@2|Bacteria,2GAQZ@200795|Chloroflexi,34D4H@301297|Dehalococcoidia 301297|Dehalococcoidia S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 SRR25158336_k127_552064_0 1198232.CYCME_0641 1.3e-115 379.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,460H9@72273|Thiotrichales 72273|Thiotrichales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA SRR25158336_k127_552064_3 1163617.SCD_n02655 1.109e-30 129.0 COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria 28216|Betaproteobacteria S signal sequence binding sco1 - - - - - - - - - - - - SRR25158336_k127_552064_2 314278.NB231_06006 6.776e-48 181.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1WYUV@135613|Chromatiales 135613|Chromatiales S SURF1-like protein - - - - - - - - - - - - SURF1 SRR25158336_k127_552064_5 1122604.JONR01000043_gene3183 0.000158 45.0 2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SGKJ@1236|Gammaproteobacteria,1X8YW@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 SRR25158336_k127_554910_0 1158756.AQXQ01000012_gene1350 5.587e-196 618.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1WW8H@135613|Chromatiales 135613|Chromatiales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE SRR25158336_k127_554910_6 1453496.AT03_02620 1.11e-78 268.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SRR25158336_k127_554910_10 1260251.SPISAL_05925 2.131e-28 121.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,1WZQP@135613|Chromatiales 135613|Chromatiales D Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K14160 - - - - ko00000,ko03400 - - - SulA SRR25158336_k127_554910_9 998674.ATTE01000001_gene3681 8.34e-44 162.0 2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,1S8UZ@1236|Gammaproteobacteria,46111@72273|Thiotrichales 72273|Thiotrichales S PFAM HopJ type III effector protein - - - - - - - - - - - - HopJ SRR25158336_k127_554910_11 1117319.PSPO_02870 1.465e-14 78.0 arCOG08935@1|root,32Z08@2|Bacteria,1NC5T@1224|Proteobacteria,1SDD7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_554910_8 2340.JV46_29150 3.917e-45 166.0 COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,1J6MN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions ppnP GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 ko:K09913 ko00230,ko00240,map00230,map00240 - R01561,R01570,R01863,R01876,R02147,R02296,R02297 RC00063,RC00122 ko00000,ko00001,ko01000 - - - DUF1255 SRR25158336_k127_554910_4 472759.Nhal_0576 2.333e-105 349.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 SRR25158336_k127_554910_2 1049564.TevJSym_ao00680 8.266e-141 457.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1J4UD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S11 family dacA GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664 PBP5_C,Peptidase_S11 SRR25158336_k127_554910_7 1286106.MPL1_05419 3.796e-73 259.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,4610F@72273|Thiotrichales 72273|Thiotrichales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR SRR25158336_k127_554910_5 1453501.JELR01000002_gene140 2.01e-99 336.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4659R@72275|Alteromonadaceae 1236|Gammaproteobacteria M Lytic murein transglycosylase mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 SRR25158336_k127_554910_3 1049564.TevJSym_ao00710 4.355e-139 451.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1J4JQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE SRR25158336_k127_554910_1 1049564.TevJSym_ao00720 7.248e-195 621.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1J4EU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase SRR25158336_k127_559905_1 1485544.JQKP01000007_gene1988 7.402e-16 81.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,44VSS@713636|Nitrosomonadales 28216|Betaproteobacteria CO TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin SRR25158336_k127_559905_0 1049564.TevJSym_ad01660 1.601e-181 577.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1J4J1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Cytochrome c-type biogenesis protein ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm SRR25158336_k127_562301_13 1163617.SCD_n00114 4.529e-10 62.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VM13@28216|Betaproteobacteria 28216|Betaproteobacteria M rhs-related protein - - - - - - - - - - - - RHS,RHS_repeat SRR25158336_k127_562301_7 2340.JV46_02910 1.351e-24 104.0 2EIMJ@1|root,33CCU@2|Bacteria,1NMXZ@1224|Proteobacteria,1SHQA@1236|Gammaproteobacteria,1J797@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_562301_5 713587.THITH_00160 2.697e-49 184.0 2C0QF@1|root,32R7C@2|Bacteria,1MYZK@1224|Proteobacteria,1S9C2@1236|Gammaproteobacteria,1WZYB@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_562301_8 243233.MCA0044 2.314e-24 104.0 2E3CN@1|root,32YBX@2|Bacteria,1N716@1224|Proteobacteria,1SEFN@1236|Gammaproteobacteria,1XGNQ@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - SRR25158336_k127_562301_6 1122603.ATVI01000013_gene1331 1.221e-24 111.0 COG2885@1|root,COG2885@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1XA7T@135614|Xanthomonadales 135614|Xanthomonadales M OmpA family - - - - - - - - - - - - OmpA SRR25158336_k127_562301_10 317025.Tcr_0270 5.147e-20 95.0 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,462W0@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - SRR25158336_k127_562301_2 396588.Tgr7_0294 7.028e-84 290.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1X0UF@135613|Chromatiales 135613|Chromatiales NU Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,TPR_16 SRR25158336_k127_562301_14 768671.ThimaDRAFT_2834 9.651e-08 59.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S0BJ@1236|Gammaproteobacteria,1X2F4@135613|Chromatiales 135613|Chromatiales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SRR25158336_k127_562301_11 1123392.AQWL01000002_gene1843 6.797e-14 76.0 2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - SRR25158336_k127_562301_9 1121374.KB891576_gene270 1.32e-23 102.0 COG2388@1|root,COG2388@2|Bacteria,1PN9M@1224|Proteobacteria,1SDBK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S GCN5-related N-acetyl-transferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG SRR25158336_k127_562301_3 439235.Dalk_1685 1.215e-53 196.0 COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria,2MK5V@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM SEC-C motif - - - ko:K09858 - - - - ko00000 - - - SEC-C SRR25158336_k127_562301_1 1163617.SCD_n02702 2.055e-130 424.0 28I2K@1|root,2ZAEK@2|Bacteria,1R9HK@1224|Proteobacteria,2VZM5@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_562301_0 519989.ECTPHS_12203 4.941e-202 636.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RS8H@1236|Gammaproteobacteria,1WWVZ@135613|Chromatiales 135613|Chromatiales C Belongs to the citrate synthase family - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt SRR25158336_k127_562301_4 595460.RRSWK_04882 7.354e-52 190.0 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 SRR25158336_k127_565646_0 1279009.ADICEAN_01147 2e-323 1000.0 COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia 976|Bacteroidetes C Monomeric isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH SRR25158336_k127_565652_0 1349767.GJA_1319 5.516e-161 556.0 COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,1MVV1@1224|Proteobacteria,2VMY9@28216|Betaproteobacteria 28216|Betaproteobacteria M Insecticidal toxin complex protein TcaC - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS SRR25158336_k127_567908_1 765912.Thimo_1749 2.595e-112 374.0 28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,1RMA6@1236|Gammaproteobacteria,1WX53@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_567908_2 402626.Rpic_0211 8.603e-29 117.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,1K8MR@119060|Burkholderiaceae 28216|Betaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin SRR25158336_k127_567908_0 1255043.TVNIR_2716 1.246e-178 568.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1WW79@135613|Chromatiales 135613|Chromatiales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase SRR25158336_k127_56873_3 1163617.SCD_n01354 6.552e-61 214.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria 28216|Betaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM,DctQ SRR25158336_k127_56873_4 519989.ECTPHS_03567 3.183e-59 213.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1WX9X@135613|Chromatiales 135613|Chromatiales O PFAM Peptidase M22, glycoprotease - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 SRR25158336_k127_56873_1 1049564.TevJSym_bw00090 2.076e-229 728.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1J5D0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria KL HELICc2 yoaA GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII SRR25158336_k127_56873_5 713586.KB900536_gene636 2.275e-20 99.0 COG0457@1|root,COG0457@2|Bacteria,1N3T7@1224|Proteobacteria 1224|Proteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 SRR25158336_k127_56873_0 1207076.ALAT01000221_gene3512 3.302e-258 816.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1YZZJ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H SRR25158336_k127_56873_2 1307759.JOMJ01000004_gene2828 2.095e-62 224.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 SRR25158336_k127_568925_0 768671.ThimaDRAFT_2027 7.987e-107 353.0 COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1WXKB@135613|Chromatiales 135613|Chromatiales S pfam php - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP SRR25158336_k127_568925_5 2340.JV46_08440 0.0001803 47.0 28JN1@1|root,2Z9EG@2|Bacteria,1R8TZ@1224|Proteobacteria,1S1S0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_568925_1 1123518.ARWI01000001_gene177 4.141e-67 234.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,460TE@72273|Thiotrichales 72273|Thiotrichales D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA SRR25158336_k127_568925_2 1118153.MOY_03778 1.902e-42 158.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1XKEK@135619|Oceanospirillales 135619|Oceanospirillales S YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the yciI - - ko:K09780 - - - - ko00000 - - - YCII SRR25158336_k127_568925_4 243233.MCA1644 4.179e-25 108.0 COG0271@1|root,COG0271@2|Bacteria,1QCDN@1224|Proteobacteria,1THS7@1236|Gammaproteobacteria,1XFIA@135618|Methylococcales 135618|Methylococcales T Belongs to the BolA IbaG family - - - ko:K05527 - - - - ko00000,ko03000 - - - BolA SRR25158336_k127_568925_3 396588.Tgr7_2020 3.906e-29 124.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1X2I5@135613|Chromatiales 135613|Chromatiales M peptidylprolyl isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3 SRR25158336_k127_572382_0 396588.Tgr7_0572 6.355e-170 545.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1WX9B@135613|Chromatiales 135613|Chromatiales E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 SRR25158336_k127_572382_1 713586.KB900536_gene1555 5.476e-160 513.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1WX3F@135613|Chromatiales 135613|Chromatiales E Belongs to the peptidase M20A family. ArgE subfamily - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 SRR25158336_k127_572382_2 105559.Nwat_2894 1.294e-132 433.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg SRR25158336_k127_583912_1 519989.ECTPHS_04299 3.473e-26 118.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1X1FM@135613|Chromatiales 135613|Chromatiales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL SRR25158336_k127_583912_0 396588.Tgr7_0237 1.771e-29 124.0 COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1SCSU@1236|Gammaproteobacteria,1WZQA@135613|Chromatiales 135613|Chromatiales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM SRR25158336_k127_584631_1 1122194.AUHU01000007_gene299 6.562e-63 227.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,466TY@72275|Alteromonadaceae 1236|Gammaproteobacteria S Cytochrome C biogenesis protein transmembrane region braZ - - ko:K09792 - - - - ko00000 - - - DsbD_2 SRR25158336_k127_584631_0 1163408.UU9_11893 1.835e-80 270.0 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN SRR25158336_k127_594347_1 1283300.ATXB01000001_gene649 1.291e-94 316.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XET3@135618|Methylococcales 135618|Methylococcales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC SRR25158336_k127_594347_4 1198232.CYCME_0521 9.152e-45 167.0 2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,462RV@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - SRR25158336_k127_594347_0 1123393.KB891331_gene2925 9.333e-155 501.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,Radical_SAM SRR25158336_k127_594347_2 580332.Slit_2150 1.517e-67 240.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - SRR25158336_k127_594347_3 335283.Neut_1769 2.839e-48 183.0 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity ugpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD SRR25158336_k127_594347_5 335283.Neut_1770 9.019e-29 117.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,372VF@32003|Nitrosomonadales 28216|Betaproteobacteria C PFAM FAD dependent oxidoreductase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C SRR25158336_k127_595396_0 396588.Tgr7_0992 2.232e-199 632.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 SRR25158336_k127_595396_1 1485544.JQKP01000010_gene807 4.338e-19 87.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,44VM8@713636|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB SRR25158336_k127_597999_2 83406.HDN1F_30540 6.455e-11 65.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 SRR25158336_k127_597999_1 1123368.AUIS01000005_gene449 1.098e-40 154.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2NC1E@225057|Acidithiobacillales 225057|Acidithiobacillales T Response regulator receiver domain - - - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Sigma54_activat SRR25158336_k127_597999_0 1049564.TevJSym_as00150 4.336e-144 480.0 COG0586@1|root,COG0586@2|Bacteria,1R0F3@1224|Proteobacteria,1RPDS@1236|Gammaproteobacteria,1JAB5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Acid phosphatase homologues lssY - - ko:K03975 - - - - ko00000 - - - LssY_C,PAP2,SNARE_assoc SRR25158336_k127_598_1 314231.FP2506_17149 6.302e-30 121.0 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,2UFMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - SRR25158336_k127_598_0 1535422.ND16A_3952 9.54e-54 192.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria,2Q830@267889|Colwelliaceae 1236|Gammaproteobacteria K helix_turn_helix, mercury resistance - - - ko:K08365,ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 SRR25158336_k127_601874_1 1005048.CFU_2831 1.413e-37 145.0 COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2VUPP@28216|Betaproteobacteria,474RD@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 SRR25158336_k127_601874_0 1095769.CAHF01000022_gene128 1.024e-55 200.0 COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VPEY@28216|Betaproteobacteria,474NJ@75682|Oxalobacteraceae 28216|Betaproteobacteria E LysE type translocator leuE_1 - - - - - - - - - - - LysE SRR25158336_k127_603414_0 1163617.SCD_n01888 1.153e-229 717.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK SRR25158336_k127_603414_2 1049564.TevJSym_by00060 1.001e-38 148.0 2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,1SDCV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_603414_1 391615.ABSJ01000022_gene320 3.444e-85 287.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid SRR25158336_k127_603646_2 768671.ThimaDRAFT_0290 7.755e-144 468.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales 135613|Chromatiales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH SRR25158336_k127_603646_1 870187.Thini_1102 3.459e-165 527.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales 72273|Thiotrichales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 SRR25158336_k127_603646_5 1163409.UUA_02031 1.429e-81 280.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales 135614|Xanthomonadales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 SRR25158336_k127_603646_6 1049564.TevJSym_as00740 7.85e-17 85.0 2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,1S5H3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_603646_4 1283300.ATXB01000001_gene2421 2.637e-92 310.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XDNG@135618|Methylococcales 135618|Methylococcales H ThiF family - - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF SRR25158336_k127_603646_3 1234364.AMSF01000070_gene2161 3.244e-103 349.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1X4WZ@135614|Xanthomonadales 1236|Gammaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C SRR25158336_k127_603646_0 396588.Tgr7_0517 4.372e-237 740.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales 135613|Chromatiales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey SRR25158336_k127_610386_1 1049564.TevJSym_bv00110 6.147e-115 377.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1J5PE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SRR25158336_k127_610386_3 1552758.NC00_01485 1.629e-15 81.0 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1SGCU@1236|Gammaproteobacteria,1X85B@135614|Xanthomonadales 135614|Xanthomonadales H Thiamine biosynthesis protein ThiS thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS SRR25158336_k127_610386_0 765914.ThisiDRAFT_2162 3.996e-136 437.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1WW65@135613|Chromatiales 135613|Chromatiales H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG SRR25158336_k127_610386_2 589865.DaAHT2_0631 2.505e-111 365.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales 28221|Deltaproteobacteria M Mechanosensitive ion channel mscS-2 - - - - - - - - - - - MS_channel SRR25158336_k127_613537_0 1198232.CYCME_1443 1.82e-76 269.0 COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,461CW@72273|Thiotrichales 72273|Thiotrichales S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C SRR25158336_k127_613537_1 194867.ALBQ01000007_gene2180 1.681e-07 61.0 COG3182@1|root,COG3182@2|Bacteria,1R59B@1224|Proteobacteria,2U5IQ@28211|Alphaproteobacteria,2KCSZ@204457|Sphingomonadales 204457|Sphingomonadales S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM SRR25158336_k127_616082_1 105559.Nwat_0767 1.62e-93 312.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales 135613|Chromatiales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM SRR25158336_k127_616082_2 396588.Tgr7_2050 8.605e-58 210.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV pilus biogenesis stability protein PilW - - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 SRR25158336_k127_616082_3 395493.BegalDRAFT_3455 7.083e-17 87.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RVX4@1236|Gammaproteobacteria,4636S@72273|Thiotrichales 72273|Thiotrichales S Domain of unknown function (DUF4115) - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 SRR25158336_k127_616082_0 396588.Tgr7_2048 4.17e-182 578.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1WWGZ@135613|Chromatiales 135613|Chromatiales J PFAM tRNA synthetase class II (G H P and S) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His SRR25158336_k127_620753_2 1121921.KB898706_gene2960 1.826e-20 99.0 COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QWRQ@1224|Proteobacteria 1224|Proteobacteria M 6-phosphogluconolactonase activity - - - - - - - - - - - - 5_nucleotid_C,NHL SRR25158336_k127_620753_0 396588.Tgr7_0678 1.209e-138 446.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1WWM6@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate SRR25158336_k127_620753_1 1454004.AW11_02008 9.785e-28 116.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,1KQVQ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Biotin-lipoyl like - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 SRR25158336_k127_631723_2 349521.HCH_04774 1.436e-65 228.0 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1XJJU@135619|Oceanospirillales 135619|Oceanospirillales M Transglycosylase SLT domain - - - - - - - - - - - - SLT SRR25158336_k127_631723_0 754476.Q7A_2254 7.806e-260 811.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,46011@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit SRR25158336_k127_631723_3 1049564.TevJSym_af00590 4.456e-40 152.0 COG1942@1|root,COG1942@2|Bacteria,1N1GC@1224|Proteobacteria,1SB41@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM macrophage migration inhibitory factor - - - - - - - - - - - - MIF SRR25158336_k127_631723_4 1049564.TevJSym_af00580 0.0007604 49.0 2A494@1|root,30SUJ@2|Bacteria,1NCCT@1224|Proteobacteria,1SX6S@1236|Gammaproteobacteria,1J77W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 SRR25158336_k127_631723_1 396588.Tgr7_2158 7.246e-209 655.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales 135613|Chromatiales E TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N SRR25158336_k127_64641_2 1232683.ADIMK_0189 7.836e-113 372.0 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,1S01Y@1236|Gammaproteobacteria,46AE9@72275|Alteromonadaceae 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 SRR25158336_k127_64641_0 1123073.KB899241_gene1855 3.498e-163 520.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1X3CD@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 SRR25158336_k127_64641_1 713586.KB900536_gene2953 3.562e-141 464.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales 135613|Chromatiales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N SRR25158336_k127_64641_4 1279015.KB908463_gene2067 2.856e-44 165.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1Y4H6@135624|Aeromonadales 135624|Aeromonadales S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE SRR25158336_k127_64641_3 472759.Nhal_3430 1.013e-54 199.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1WX8Q@135613|Chromatiales 135613|Chromatiales M Cell wall hydrolase autolysin - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM SRR25158336_k127_64963_2 1123400.KB904754_gene964 4.443e-33 131.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,45ZWW@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N SRR25158336_k127_64963_0 105559.Nwat_2897 1.378e-207 654.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales 135613|Chromatiales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 SRR25158336_k127_64963_1 713587.THITH_03555 1.828e-59 209.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales 135613|Chromatiales J binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N SRR25158336_k127_65160_0 1449063.JMLS01000002_gene1410 5.662e-118 393.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,26RI3@186822|Paenibacillaceae 91061|Bacilli G Catalyzes the formation of phosphoenolpyruvate from pyruvate pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C SRR25158336_k127_65160_1 765912.Thimo_1350 3.263e-78 276.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1WWTV@135613|Chromatiales 135613|Chromatiales O TIGRFAM Cytochrome c-type biogenesis protein CcmI - - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_2 SRR25158336_k127_65160_2 1049564.TevJSym_ad01640 2.066e-39 150.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1J6GH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200 - - - - ko00000 - - - CcmH SRR25158336_k127_654383_3 156889.Mmc1_2003 7.21e-17 82.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Sel1 domain protein repeat-containing protein - - - ko:K07126 - - - - ko00000 - - - Sel1 SRR25158336_k127_654383_0 870187.Thini_1979 1.117e-153 493.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,45ZTU@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA SRR25158336_k127_654383_1 765913.ThidrDRAFT_2643 1.717e-121 402.0 28HU5@1|root,2Z80X@2|Bacteria,1R55N@1224|Proteobacteria,1RMAG@1236|Gammaproteobacteria,1WWIS@135613|Chromatiales 135613|Chromatiales S TIGRFAM TIGR03790 family protein - - - - - - - - - - - - - SRR25158336_k127_654383_4 580332.Slit_0478 1.27e-09 64.0 COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W6J@713636|Nitrosomonadales 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - DUF4118,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd SRR25158336_k127_654383_2 519989.ECTPHS_12403 1.777e-21 98.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,1WYG0@135613|Chromatiales 135613|Chromatiales N Host attachment protein - - - - - - - - - - - - Host_attach SRR25158336_k127_660084_0 396588.Tgr7_0087 4.174e-213 674.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales 135613|Chromatiales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 SRR25158336_k127_660084_1 1158762.KB898037_gene2336 5.446e-119 390.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria,1WXV0@135613|Chromatiales 135613|Chromatiales S Cytokinin riboside 5'-monophosphate phosphoribohydrolase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox SRR25158336_k127_660084_2 396588.Tgr7_0085 7.909e-26 110.0 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria,1WZ2H@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 SRR25158336_k127_660084_3 1286106.MPL1_03915 1.425e-25 108.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,460A9@72273|Thiotrichales 72273|Thiotrichales F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH,TusA SRR25158336_k127_668014_3 1004785.AMBLS11_18230 3.297e-21 96.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,4658F@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG1450 Type II secretory pathway, component PulD gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N SRR25158336_k127_668014_0 713586.KB900536_gene2363 1.379e-220 696.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N SRR25158336_k127_668014_1 519989.ECTPHS_04329 1.046e-161 518.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales 135613|Chromatiales U General secretion pathway protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF SRR25158336_k127_668014_2 314278.NB231_13481 4.135e-74 258.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1WXST@135613|Chromatiales 135613|Chromatiales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos SRR25158336_k127_669592_2 1163617.SCD_n02041 4.877e-122 399.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp SRR25158336_k127_669592_3 2340.JV46_03220 9.76e-91 308.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1J6QH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T HPP family - - - ko:K07168 - - - - ko00000 - - - HPP SRR25158336_k127_669592_5 314285.KT71_07424 7.413e-50 185.0 2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,1SMYA@1236|Gammaproteobacteria,1J9DI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_669592_7 472759.Nhal_3516 2.012e-16 87.0 2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,1SGAI@1236|Gammaproteobacteria,1WZTM@135613|Chromatiales 135613|Chromatiales S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N SRR25158336_k127_669592_6 1121920.AUAU01000011_gene137 2.08e-28 123.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT SRR25158336_k127_669592_4 1051646.VITU9109_13207 3.73e-82 277.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,1XVHC@135623|Vibrionales 135623|Vibrionales L COG1573 Uracil-DNA glycosylase - - - - - - - - - - - - UDG SRR25158336_k127_669592_1 1249627.D779_3611 9.847e-267 834.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1WWHQ@135613|Chromatiales 135613|Chromatiales H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C SRR25158336_k127_669592_0 1198232.CYCME_0386 0.0 1073.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,4607G@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SRR25158336_k127_675348_2 549.BW31_04436 1.749e-58 206.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,3VXQY@53335|Pantoea 1236|Gammaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 SRR25158336_k127_675348_1 2340.JV46_03650 1.978e-108 360.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RR4I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SRR25158336_k127_675348_0 754477.Q7C_1613 3.167e-155 503.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,46060@72273|Thiotrichales 72273|Thiotrichales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT SRR25158336_k127_675348_3 1415778.JQMM01000001_gene1445 8.741e-06 49.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,1JC11@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Phage integrase family Z012_07715 - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase SRR25158336_k127_676229_1 105559.Nwat_2747 3.38e-73 263.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales 135613|Chromatiales M PFAM LppC - - - ko:K07121 - - - - ko00000 - - - LppC SRR25158336_k127_676229_0 743721.Psesu_0630 5.714e-97 325.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1X4QV@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase SRR25158336_k127_676229_2 203122.Sde_0009 1.896e-62 220.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T30G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_4 SRR25158336_k127_679716_0 1049564.TevJSym_ao00360 1.638e-101 335.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1J50Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S related to Ser Thr protein kinases - GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH SRR25158336_k127_679716_4 2340.JV46_17280 1.938e-33 131.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,1J5S4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Predicted membrane protein (DUF2238) yjdF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08984 - - - - ko00000 - - - DUF2238 SRR25158336_k127_679716_1 1415778.JQMM01000001_gene162 7.767e-72 252.0 COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,1S3TT@1236|Gammaproteobacteria,1J9ZE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 SRR25158336_k127_679716_2 713587.THITH_08965 3.343e-41 157.0 2E0WU@1|root,32WDV@2|Bacteria,1N1G5@1224|Proteobacteria,1S9KI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_679716_3 396588.Tgr7_0266 1.86e-34 134.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase SRR25158336_k127_68388_2 113395.AXAI01000013_gene6795 9.478e-18 86.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,3JSWN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O prohibitin homologues qmcA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Band_7,Band_7_C SRR25158336_k127_68388_1 1049564.TevJSym_ak00290 9.509e-25 109.0 COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,1S5W4@1236|Gammaproteobacteria,1J7C6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria OU NfeD-like C-terminal, partner-binding ybbJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07340 - - - - ko00000 - - - NfeD SRR25158336_k127_68388_0 391615.ABSJ01000026_gene110 1.362e-75 274.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding SRR25158336_k127_68388_3 765912.Thimo_0115 1.828e-14 80.0 2C8T8@1|root,32RMU@2|Bacteria,1N089@1224|Proteobacteria,1SAT4@1236|Gammaproteobacteria,1WYU4@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_68388_4 572479.Hprae_0040 2.37e-07 53.0 COG1076@1|root,COG1076@2|Bacteria 2|Bacteria O ATPase activator activity djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB SRR25158336_k127_684023_0 396588.Tgr7_3073 5.031e-133 431.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1WXWQ@135613|Chromatiales 135613|Chromatiales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SRR25158336_k127_684023_1 2340.JV46_13280 3.957e-48 186.0 2E1WQ@1|root,32X5W@2|Bacteria,1N2F8@1224|Proteobacteria,1SA2N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_684023_4 1120963.KB894496_gene2675 2.57e-06 50.0 2DS85@1|root,33EYM@2|Bacteria,1NJQN@1224|Proteobacteria,1SHH9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_684567_4 2340.JV46_20660 2.117e-30 122.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1J4NM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 SRR25158336_k127_684567_3 1122201.AUAZ01000004_gene3319 6.335e-35 134.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,4682T@72275|Alteromonadaceae 1236|Gammaproteobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 SRR25158336_k127_684567_1 1249627.D779_4177 3.464e-125 407.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N SRR25158336_k127_684567_2 519989.ECTPHS_07252 1.962e-36 141.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales 135613|Chromatiales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA SRR25158336_k127_684567_0 2340.JV46_20620 9.172e-187 591.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1J4HS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc SRR25158336_k127_696429_1 287.DR97_744 7.272e-66 229.0 28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,1RQV1@1236|Gammaproteobacteria,1YD9U@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Yip1 domain yohC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - - - - - - - - - - DUF1282 SRR25158336_k127_696429_2 396588.Tgr7_2534 4.773e-53 194.0 COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1X1AR@135613|Chromatiales 135613|Chromatiales M OmpW family - - - ko:K07275 - - - - ko00000 - - - OmpW SRR25158336_k127_696429_3 1318628.MARLIPOL_17278 3.634e-26 115.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae 1236|Gammaproteobacteria NU COG4968 Tfp pilus assembly protein PilE pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl SRR25158336_k127_696429_0 349521.HCH_05927 1.863e-110 373.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XISX@135619|Oceanospirillales 135619|Oceanospirillales NU Tfp pilus assembly protein, tip-associated adhesin PilY1 - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC SRR25158336_k127_696823_0 243233.MCA0969 3.894e-218 689.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1XDUX@135618|Methylococcales 135618|Methylococcales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase SRR25158336_k127_699595_4 555778.Hneap_2121 2.244e-30 122.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWG5@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K09695 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC_tran SRR25158336_k127_699595_0 1123368.AUIS01000011_gene1190 2.097e-96 322.0 COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,1S29T@1236|Gammaproteobacteria,2NCSV@225057|Acidithiobacillales 225057|Acidithiobacillales V ABC-2 type transporter - - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane SRR25158336_k127_699595_2 870187.Thini_3621 2.885e-63 219.0 28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,1SEW0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_699595_3 572477.Alvin_0802 6.059e-49 180.0 COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,1S4C9@1236|Gammaproteobacteria,1X2AK@135613|Chromatiales 135613|Chromatiales CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,Redoxin SRR25158336_k127_699595_1 1123368.AUIS01000006_gene572 2.139e-65 231.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales 225057|Acidithiobacillales S SOS response associated peptidase (SRAP) - - - - - - - - - - - - SRAP SRR25158336_k127_700897_0 1335757.SPICUR_06640 1.868e-293 916.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales 135613|Chromatiales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N SRR25158336_k127_700897_1 472759.Nhal_2294 3.037e-80 277.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1WWTY@135613|Chromatiales 135613|Chromatiales FP Belongs to the GppA Ppx family - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA SRR25158336_k127_701368_2 572477.Alvin_0295 6.027e-33 128.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1WVWF@135613|Chromatiales 135613|Chromatiales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC SRR25158336_k127_701368_3 1122599.AUGR01000021_gene3236 3.499e-26 116.0 COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,1SBRN@1236|Gammaproteobacteria,1XKIM@135619|Oceanospirillales 135619|Oceanospirillales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 SRR25158336_k127_701368_0 519989.ECTPHS_07491 9.557e-81 278.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales 135613|Chromatiales KT Response regulator of the LytR AlgR family - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg SRR25158336_k127_701368_1 1049564.TevJSym_bb00370 1.907e-40 154.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1J5V1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase SRR25158336_k127_706408_0 269799.Gmet_1669 1.665e-169 552.0 COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria 28221|Deltaproteobacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec SRR25158336_k127_706408_1 1123253.AUBD01000002_gene1427 5.184e-14 76.0 2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,1SDBT@1236|Gammaproteobacteria,1XBCB@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4154) - - - - - - - - - - - - DUF4154 SRR25158336_k127_706807_2 314278.NB231_15413 1.201e-27 114.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1WWHC@135613|Chromatiales 135613|Chromatiales J Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C SRR25158336_k127_706807_1 697282.Mettu_2454 6.484e-29 121.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1XFBI@135618|Methylococcales 135618|Methylococcales S RDD family - - - - - - - - - - - - RDD SRR25158336_k127_706807_0 396588.Tgr7_2138 1.1e-90 314.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1WWXY@135613|Chromatiales 135613|Chromatiales S Permease YjgP YjgQ - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ SRR25158336_k127_706807_3 1283300.ATXB01000001_gene1369 3.912e-25 108.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1XDW7@135618|Methylococcales 135618|Methylococcales S Permease YjgP YjgQ - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ SRR25158336_k127_711027_0 243233.MCA0098 6.384e-239 745.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XDYT@135618|Methylococcales 135618|Methylococcales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase SRR25158336_k127_711027_2 322710.Avin_12640 7.746e-34 132.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln SRR25158336_k127_711027_1 1286106.MPL1_05389 2.778e-92 304.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,4602K@72273|Thiotrichales 72273|Thiotrichales D TIGRFAM Cell shape determining protein MreB Mrl - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SRR25158336_k127_715338_0 1123392.AQWL01000003_gene150 1.259e-178 571.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,1KSM8@119069|Hydrogenophilales 119069|Hydrogenophilales O HypF finger - - - - - - - - - - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF SRR25158336_k127_715338_3 396588.Tgr7_0577 7.377e-25 106.0 COG2608@1|root,COG2608@2|Bacteria 2|Bacteria P mercury ion transmembrane transporter activity copZ - - ko:K07213 ko04978,map04978 - - - ko00000,ko00001 - - - HMA SRR25158336_k127_715338_1 2340.JV46_24270 5.327e-149 480.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1JA5R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O AIR synthase related protein, N-terminal domain hypE GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C SRR25158336_k127_715338_2 580332.Slit_2117 4.819e-61 216.0 COG0475@1|root,COG0475@2|Bacteria,1PK6U@1224|Proteobacteria,2WAEY@28216|Betaproteobacteria,44WJS@713636|Nitrosomonadales 28216|Betaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger SRR25158336_k127_720324_0 301.JNHE01000014_gene2907 1.237e-194 610.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria 1236|Gammaproteobacteria C UPF0313 protein ygiQ - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N SRR25158336_k127_728915_0 472759.Nhal_0265 3.93e-151 497.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1WW2F@135613|Chromatiales 135613|Chromatiales P Chloride channel - - - - - - - - - - - - Voltage_CLC SRR25158336_k127_728915_1 1049564.TevJSym_as00070 1.767e-80 271.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1J549@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC SRR25158336_k127_73013_3 582744.Msip34_1399 9.522e-28 114.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KM0C@206350|Nitrosomonadales 206350|Nitrosomonadales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep SRR25158336_k127_73013_0 765911.Thivi_2758 6.123e-115 382.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales 135613|Chromatiales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB SRR25158336_k127_73013_1 1121374.KB891586_gene2463 4.457e-73 253.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII SRR25158336_k127_73013_2 713587.THITH_15175 3.802e-57 207.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1T54V@1236|Gammaproteobacteria,1X2UH@135613|Chromatiales 135613|Chromatiales T diguanylate cyclase - - - - - - - - - - - - GGDEF SRR25158336_k127_731075_0 105559.Nwat_1801 2.36e-204 647.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales 135613|Chromatiales O PFAM Magnesium chelatase, ChlI subunit - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SRR25158336_k127_731075_1 765913.ThidrDRAFT_1827 3.513e-32 130.0 2E94J@1|root,333DE@2|Bacteria,1N7Q9@1224|Proteobacteria,1SEA8@1236|Gammaproteobacteria,1WYCC@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_731075_2 243090.RB1656 2.858e-22 98.0 COG2199@1|root,COG3290@1|root,COG3437@1|root,COG3290@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,2IYJM@203682|Planctomycetes 203682|Planctomycetes T GGDEF domain - - - - - - - - - - - - GGDEF,HD,PAS_4 SRR25158336_k127_731075_3 1163617.SCD_n00017 1.024e-17 83.0 28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,2VPIS@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_750660_1 1177179.A11A3_03764 6.642e-64 223.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XJD4@135619|Oceanospirillales 135619|Oceanospirillales P COG1392 Phosphate transport regulator (distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div SRR25158336_k127_750660_0 396588.Tgr7_2469 4.357e-198 624.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1WX8S@135613|Chromatiales 135613|Chromatiales P PFAM phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 SRR25158336_k127_750660_2 713586.KB900536_gene1964 1.412e-56 203.0 COG0705@1|root,COG0705@2|Bacteria,1RJYI@1224|Proteobacteria,1S0FR@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid SRR25158336_k127_750660_3 876044.IMCC3088_265 5.875e-55 198.0 296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,1S5WC@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_751783_2 1117318.PRUB_22255 3.099e-62 216.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,2PZCV@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_2002,iYL1228.KPN_01074 Amidohydro_1 SRR25158336_k127_751783_1 1049564.TevJSym_an00750 5.37e-88 298.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1J5U7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T SRR25158336_k127_751783_4 1123368.AUIS01000006_gene590 1.096e-51 188.0 2BKU0@1|root,32FA8@2|Bacteria,1RJX5@1224|Proteobacteria,1SJ45@1236|Gammaproteobacteria,2NCXG@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - SRR25158336_k127_751783_3 870187.Thini_0394 8.553e-52 184.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales 72273|Thiotrichales C Belongs to the glutaredoxin family. Monothiol subfamily grxD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin SRR25158336_k127_751783_0 713586.KB900536_gene1253 1.929e-184 584.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales 135613|Chromatiales E Asparagine synthase, glutamine-hydrolyzing - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SRR25158336_k127_755090_2 1049564.TevJSym_as00390 1.078e-49 181.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM SRR25158336_k127_755090_0 1049564.TevJSym_as00400 7.629e-58 206.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1J63A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q transport system, small permease component gtrA - - - - - - - - - - - DctQ SRR25158336_k127_755090_1 1163617.SCD_n00047 1.033e-50 184.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH SRR25158336_k127_76622_3 2340.JV46_26320 7.398e-27 109.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1J6G6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p SRR25158336_k127_76622_1 396588.Tgr7_3207 3.03e-38 144.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1WYVD@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 SRR25158336_k127_76622_0 713586.KB900536_gene1912 2.938e-149 479.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1WX4T@135613|Chromatiales 135613|Chromatiales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 SRR25158336_k127_76622_2 765914.ThisiDRAFT_1306 3.884e-37 143.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA SRR25158336_k127_770617_0 1049564.TevJSym_at00750 4.945e-86 287.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1J5R6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iJN746.PP_0538,iPC815.YPO3521 Pyrophosphatase SRR25158336_k127_770617_1 1488328.JMCL01000030_gene2208 8.868e-34 134.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc SRR25158336_k127_770617_3 1216966.BAUC01000010_gene2317 0.0001907 45.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C SRR25158336_k127_770617_2 1307759.JOMJ01000004_gene2462 2.578e-28 123.0 COG2010@1|root,COG2010@2|Bacteria,1RIY5@1224|Proteobacteria 1224|Proteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 SRR25158336_k127_770932_5 1286106.MPL1_09410 6.046e-05 46.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,46007@72273|Thiotrichales 72273|Thiotrichales S DNA recombination protein RmuC - - - ko:K09760 - - - - ko00000 - - - RmuC SRR25158336_k127_770932_3 395493.BegalDRAFT_3110 5.658e-77 267.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,460UW@72273|Thiotrichales 72273|Thiotrichales IQ short-chain dehydrogenase reductase - - - - - - - - - - - - adh_short SRR25158336_k127_770932_4 1415778.JQMM01000001_gene1251 2.47e-34 135.0 2DP6U@1|root,330T2@2|Bacteria,1N7R9@1224|Proteobacteria,1SDI8@1236|Gammaproteobacteria,1JA9T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_OmpA,Gly-zipper_YMGG SRR25158336_k127_770932_0 2340.JV46_06350 9.531e-110 367.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,1RZ7R@1236|Gammaproteobacteria,1JA4U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 SRR25158336_k127_770932_2 765912.Thimo_1834 2.298e-79 270.0 COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales 135613|Chromatiales L PFAM HhH-GPD - - - ko:K07457 - - - - ko00000 - - - HhH-GPD SRR25158336_k127_770932_1 396588.Tgr7_2010 7.593e-99 329.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales 135613|Chromatiales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SRR25158336_k127_774108_0 713586.KB900536_gene1464 1.074e-105 361.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,1X2J4@135613|Chromatiales 135613|Chromatiales T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP SRR25158336_k127_775021_5 713587.THITH_10750 2.146e-26 109.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1WW2U@135613|Chromatiales 135613|Chromatiales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SRR25158336_k127_775021_1 713586.KB900536_gene61 9.695e-107 352.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales 135613|Chromatiales E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA SRR25158336_k127_775021_0 519989.ECTPHS_11355 7.834e-218 680.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales 135613|Chromatiales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP SRR25158336_k127_775021_3 1415778.JQMM01000001_gene1613 2.406e-66 232.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1J637@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI SRR25158336_k127_775021_2 396588.Tgr7_1251 1.645e-94 316.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1WX2M@135613|Chromatiales 135613|Chromatiales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 SRR25158336_k127_775021_4 1198232.CYCME_1071 2.9e-27 120.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,460N8@72273|Thiotrichales 72273|Thiotrichales NU TIGRFAM FimV C-terminal domain - - - ko:K08086 - - - - ko00000 - - - LysM SRR25158336_k127_776433_0 572477.Alvin_0632 1.45e-304 940.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn SRR25158336_k127_776433_1 314345.SPV1_00822 4.204e-07 61.0 COG3087@1|root,COG3087@2|Bacteria 2|Bacteria D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - Antigen_C,DUF928,NYN,SPOR SRR25158336_k127_777670_9 1049564.TevJSym_af00770 3.999e-13 71.0 COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria,1J72M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins resA - - - - - - - - - - - AhpC-TSA SRR25158336_k127_777670_6 768671.ThimaDRAFT_3900 1.353e-27 113.0 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1WZC1@135613|Chromatiales 135613|Chromatiales C acylphosphatase acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase SRR25158336_k127_777670_0 396588.Tgr7_1082 4.446e-234 736.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales 135613|Chromatiales H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SRR25158336_k127_777670_3 472759.Nhal_0713 2.988e-83 280.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1WXBZ@135613|Chromatiales 135613|Chromatiales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SRR25158336_k127_777670_8 314278.NB231_01119 2.086e-15 83.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SGPC@1236|Gammaproteobacteria,1WYNC@135613|Chromatiales 135613|Chromatiales T PFAM Anti sigma-E protein RseA - - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_N SRR25158336_k127_777670_4 391615.ABSJ01000002_gene483 2.797e-60 220.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1J65J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T MucB/RseB C-terminal domain rseB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C SRR25158336_k127_777670_5 1123368.AUIS01000017_gene2572 1.65e-37 146.0 COG3086@1|root,COG3086@2|Bacteria 2|Bacteria T response to oxidative stress rseC GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K03803 - - - - ko00000,ko03021 - - - RseC_MucC SRR25158336_k127_777670_2 472759.Nhal_0717 9.738e-173 559.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 SRR25158336_k127_777670_7 859657.RPSI07_2333 3.866e-18 88.0 COG0695@1|root,COG0695@2|Bacteria,1N82H@1224|Proteobacteria,2VWG7@28216|Betaproteobacteria,1K9F5@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM glutaredoxin 2 - - - - - - - - - - - - DUF836 SRR25158336_k127_777670_1 391615.ABSJ01000002_gene479 9.912e-194 610.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1J4DD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C SRR25158336_k127_779000_0 2340.JV46_11760 6.674e-132 426.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1J4K1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the peptidase M48B family htpX GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 SRR25158336_k127_779000_1 384676.PSEEN4367 3.917e-68 234.0 COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon2 - 3.4.21.53 ko:K01338,ko:K08675 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002,ko03029 - - - AAA,LON_substr_bdg,Lon_C SRR25158336_k127_783250_2 395493.BegalDRAFT_1820 9.556e-115 375.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SRR25158336_k127_783250_1 396588.Tgr7_1183 1.807e-143 460.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1WWZU@135613|Chromatiales 135613|Chromatiales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 SRR25158336_k127_783250_0 713586.KB900536_gene118 8.923e-227 709.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales 135613|Chromatiales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase SRR25158336_k127_79063_0 396588.Tgr7_3148 9.267e-151 480.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales 135613|Chromatiales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 SRR25158336_k127_79063_3 1123368.AUIS01000001_gene1908 2.815e-08 59.0 2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_79063_2 1122603.ATVI01000006_gene526 2.328e-44 169.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1X77M@135614|Xanthomonadales 135614|Xanthomonadales FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - - - - - - - - - - HIT SRR25158336_k127_79063_1 1116472.MGMO_105c00260 2.044e-82 284.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XE1M@135618|Methylococcales 135618|Methylococcales L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC SRR25158336_k127_792088_2 396588.Tgr7_0842 2.076e-41 155.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales 135613|Chromatiales P CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 SRR25158336_k127_792088_1 502025.Hoch_5232 8.27e-53 189.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria,2YV4M@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR SRR25158336_k127_792088_0 870187.Thini_3411 3.029e-186 592.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,45ZQZ@72273|Thiotrichales 72273|Thiotrichales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - ATPase,ChlI SRR25158336_k127_792088_3 521719.ATXQ01000002_gene2357 9.707e-11 66.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YE8V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_1 SRR25158336_k127_793099_2 555778.Hneap_0045 8.553e-93 310.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase SRR25158336_k127_793099_3 472759.Nhal_2269 4.986e-89 299.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales 135613|Chromatiales JM PFAM Nucleotidyl transferase - - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase SRR25158336_k127_793099_0 472759.Nhal_2423 2.183e-182 582.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales 135613|Chromatiales S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 SRR25158336_k127_793099_1 1123368.AUIS01000019_gene1205 2.054e-134 435.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA SRR25158336_k127_793099_4 1535422.ND16A_0733 2.668e-54 195.0 COG1575@1|root,COG1575@2|Bacteria,1QHA9@1224|Proteobacteria,1TEVV@1236|Gammaproteobacteria,2Q7F8@267889|Colwelliaceae 1236|Gammaproteobacteria H UbiA prenyltransferase family - - - - - - - - - - - - UbiA SRR25158336_k127_793575_3 1027273.GZ77_12545 4.187e-62 215.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XI7F@135619|Oceanospirillales 135619|Oceanospirillales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small SRR25158336_k127_793575_2 247634.GPB2148_594 7.761e-84 282.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1J4JF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome SRR25158336_k127_793575_1 349124.Hhal_1202 8.643e-102 340.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SRR25158336_k127_793575_4 713586.KB900536_gene2181 1.472e-48 183.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF484 - - - ko:K09921 - - - - ko00000 - - - DUF484 SRR25158336_k127_793575_0 292415.Tbd_2526 2.235e-107 353.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,1KRE1@119069|Hydrogenophilales 119069|Hydrogenophilales E Diaminopimelate epimerase - - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase SRR25158336_k127_794657_0 1049564.TevJSym_bh00140 9.28e-136 435.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1J4N9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0714 MoxR-like ATPases - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SRR25158336_k127_794657_1 1049564.TevJSym_bh00130 7.295e-123 400.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1J5XC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 SRR25158336_k127_794657_4 1049564.TevJSym_bh00120 6.194e-35 141.0 2C5QF@1|root,31MIM@2|Bacteria,1QJDJ@1224|Proteobacteria,1THCP@1236|Gammaproteobacteria,1JAA3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 SRR25158336_k127_794657_2 1049564.TevJSym_bh00110 5.687e-117 386.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1J577@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 SRR25158336_k127_794657_3 1049564.TevJSym_bh00100 2.76e-72 251.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1J59K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_16,TPR_2,VWA_2 SRR25158336_k127_798629_2 472759.Nhal_0076 1.053e-55 198.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1WWNM@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt SRR25158336_k127_798629_1 1232410.KI421418_gene2437 5.533e-67 237.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,42RII@68525|delta/epsilon subdivisions,2WNS9@28221|Deltaproteobacteria,43SIS@69541|Desulfuromonadales 28221|Deltaproteobacteria M MlaA lipoprotein - - - ko:K04754 - - - - ko00000 - - - MlaA SRR25158336_k127_798629_0 2340.JV46_06370 9.506e-86 291.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1J53C@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S MazG nucleotide pyrophosphohydrolase domain mazG GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - iAF1260.b2781,iBWG_1329.BWG_2516,iE2348C_1286.E2348C_3048,iEC55989_1330.EC55989_3056,iECDH10B_1368.ECDH10B_2948,iECDH1ME8569_1439.ECDH1ME8569_2691,iECH74115_1262.ECH74115_4041,iECIAI1_1343.ECIAI1_2889,iECO103_1326.ECO103_3324,iECO111_1330.ECO111_3505,iECO26_1355.ECO26_3851,iECOK1_1307.ECOK1_3155,iECP_1309.ECP_2762,iECSE_1348.ECSE_3039,iECSP_1301.ECSP_3733,iECW_1372.ECW_m2990,iECs_1301.ECs3641,iEKO11_1354.EKO11_0987,iEcDH1_1363.EcDH1_0907,iEcE24377_1341.EcE24377A_3085,iEcHS_1320.EcHS_A2925,iEcolC_1368.EcolC_0931,iG2583_1286.G2583_3433,iJO1366.b2781,iJR904.b2781,iSBO_1134.SBO_2662,iSSON_1240.SSON_2938,iSbBS512_1146.SbBS512_E3092,iUMN146_1321.UM146_02665,iUMNK88_1353.UMNK88_3464,iUTI89_1310.UTI89_C3150,iWFL_1372.ECW_m2990,iY75_1357.Y75_RS14470,iZ_1308.Z4096 MazG SRR25158336_k127_798629_3 1279017.AQYJ01000028_gene2173 1.795e-50 185.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,46B76@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF882) ycbK - - - - - - - - - - - Peptidase_M15_2 SRR25158336_k127_798629_4 1049564.TevJSym_ac01570 1.317e-26 114.0 COG3160@1|root,COG3160@2|Bacteria 2|Bacteria K Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase rsd GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - ko:K07740 - - - - ko00000 - - - Rsd_AlgQ SRR25158336_k127_807513_0 472759.Nhal_0327 1.2e-193 620.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1WWBU@135613|Chromatiales 135613|Chromatiales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C SRR25158336_k127_807513_4 2340.JV46_25850 8.011e-26 109.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1J6V1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG1925 Phosphotransferase system, HPr-related proteins ptsO GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - ko:K08485,ko:K11189 ko02060,map02060 - - - ko00000,ko00001,ko02000 4.A.2.1 - - PTS-HPr SRR25158336_k127_807513_2 396588.Tgr7_0721 1.098e-33 136.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1WYYD@135613|Chromatiales 135613|Chromatiales G system, fructose subfamily IIA component - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man SRR25158336_k127_807513_1 243233.MCA0739 9.337e-95 319.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XE9S@135618|Methylococcales 135618|Methylococcales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 SRR25158336_k127_807513_3 1236959.BAMT01000006_gene334 5.323e-28 116.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,2KKT6@206350|Nitrosomonadales 206350|Nitrosomonadales T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N SRR25158336_k127_827816_8 195253.Syn6312_1412 6.111e-08 63.0 2C7TI@1|root,2Z9KQ@2|Bacteria,1G4XM@1117|Cyanobacteria,1H3E4@1129|Synechococcus 1117|Cyanobacteria - - - - - - - - - - - - - - - SRR25158336_k127_827816_4 28229.ND2E_1917 3.146e-74 258.0 COG3637@1|root,COG3637@2|Bacteria,1PT35@1224|Proteobacteria,1TIWY@1236|Gammaproteobacteria,2Q8FA@267889|Colwelliaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - SRR25158336_k127_827816_3 626887.J057_05751 9.447e-100 332.0 COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,1S22U@1236|Gammaproteobacteria,469TG@72275|Alteromonadaceae 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - SRR25158336_k127_827816_9 314282.PCNPT3_11490 7.837e-08 63.0 2EJJV@1|root,33DAR@2|Bacteria,1NM2P@1224|Proteobacteria,1SHAQ@1236|Gammaproteobacteria,2QI85@267894|Psychromonadaceae 1236|Gammaproteobacteria M Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 SRR25158336_k127_827816_5 525897.Dbac_1078 2.472e-48 179.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,42S9D@68525|delta/epsilon subdivisions,2WNWH@28221|Deltaproteobacteria 28221|Deltaproteobacteria S (twin-arginine translocation) pathway signal - - - - - - - - - - - - - SRR25158336_k127_827816_7 425104.Ssed_1733 2.414e-20 94.0 2DRBR@1|root,33B4T@2|Bacteria,1NHJT@1224|Proteobacteria 1224|Proteobacteria S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like SRR25158336_k127_827816_6 316275.VSAL_I1902 7.721e-37 145.0 2E1PZ@1|root,32X0D@2|Bacteria,1N001@1224|Proteobacteria,1S9M7@1236|Gammaproteobacteria,1XX5Q@135623|Vibrionales 135623|Vibrionales - - - - - - - - - - - - - - - SRR25158336_k127_827816_1 247633.GP2143_09155 4.961e-114 379.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated - - - - - - - - - - - - AI-2E_transport SRR25158336_k127_827816_0 314285.KT71_00500 1.64e-187 600.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1J7JT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane efflux protein VPA1579 - - - - - - - - - - - OEP SRR25158336_k127_827816_2 314285.KT71_00495 7.305e-103 344.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1J6F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG1566 Multidrug resistance efflux pump VVA0148 - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SRR25158336_k127_831816_1 1123236.KB899376_gene649 2.144e-101 340.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,464VS@72275|Alteromonadaceae 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SRR25158336_k127_831816_0 2340.JV46_04770 1.282e-246 775.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1J4XZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 SRR25158336_k127_832193_3 2340.JV46_03510 4.711e-29 117.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C SRR25158336_k127_832193_0 2340.JV46_03520 2.235e-220 687.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1J4P4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the phosphoglycerate kinase family pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSbBS512_1146.SbBS512_E3351 PGK SRR25158336_k127_832193_1 765911.Thivi_2347 1.61e-194 610.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1WXC0@135613|Chromatiales 135613|Chromatiales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N SRR25158336_k127_832193_2 555778.Hneap_0409 8.199e-54 191.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1WVWH@135613|Chromatiales 135613|Chromatiales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N SRR25158336_k127_836779_1 519989.ECTPHS_02821 1.514e-93 309.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales 135613|Chromatiales J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon SRR25158336_k127_836779_4 1288494.EBAPG3_11070 4.359e-48 181.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2VU6X@28216|Betaproteobacteria 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 SRR25158336_k127_836779_0 243233.MCA1220 1.68e-117 381.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XDV4@135618|Methylococcales 135618|Methylococcales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg SRR25158336_k127_836779_3 686340.Metal_2812 2.964e-58 207.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XF1A@135618|Methylococcales 135618|Methylococcales L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC SRR25158336_k127_836779_2 1323663.AROI01000016_gene470 3.42e-65 229.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N SRR25158336_k127_836779_5 579405.Dd703_2145 9.884e-18 83.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,2JCA2@204037|Dickeya 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N SRR25158336_k127_838566_0 1049564.TevJSym_at00390 6.807e-129 417.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1J4IR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - ko:K03688 - - - - ko00000 - - iYL1228.KPN_04331 ABC1 SRR25158336_k127_838566_3 1049564.TevJSym_at00400 1.888e-44 171.0 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1J6XG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yigP - - ko:K03690 - - - - ko00000 - - - SCP2 SRR25158336_k127_838566_1 2340.JV46_16290 2.29e-104 344.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1J4ZD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355 Ubie_methyltran SRR25158336_k127_838566_2 713587.THITH_00535 8.165e-49 177.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1WYD9@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 SRR25158336_k127_846740_0 765912.Thimo_2040 2.871e-119 390.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SRR25158336_k127_846740_1 90813.JQMT01000001_gene1449 1.407e-27 118.0 COG1416@1|root,COG1416@2|Bacteria,1N0U1@1224|Proteobacteria,1SGKY@1236|Gammaproteobacteria,4629B@72273|Thiotrichales 72273|Thiotrichales S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE SRR25158336_k127_846740_2 661367.LLO_0471 1.36e-06 50.0 2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - SRR25158336_k127_847044_3 396588.Tgr7_3057 1.497e-15 77.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding SRR25158336_k127_847044_1 93220.LV28_18365 2.492e-43 161.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,1K7QJ@119060|Burkholderiaceae 28216|Betaproteobacteria I Thioesterase superfamily protein yciA - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT SRR25158336_k127_847044_2 261292.Nit79A3_0695 1.591e-30 122.0 2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,2W3RS@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF5062) - - - - - - - - - - - - DUF5062 SRR25158336_k127_847044_0 472759.Nhal_3125 3.25e-103 341.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1WXA1@135613|Chromatiales 135613|Chromatiales L TIGRFAM hydrolase, TatD family - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SRR25158336_k127_854661_0 1026882.MAMP_02781 2.292e-116 379.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,4604A@72273|Thiotrichales 72273|Thiotrichales P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp SRR25158336_k127_854661_1 1255043.TVNIR_0569 1.296e-98 331.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1X0FJ@135613|Chromatiales 135613|Chromatiales P Sulfate permease family - - - - - - - - - - - - Sulfate_transp SRR25158336_k127_857924_1 472759.Nhal_3087 4.366e-63 221.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1WXKW@135613|Chromatiales 135613|Chromatiales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SRR25158336_k127_857924_0 396588.Tgr7_1907 1.232e-122 400.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N SRR25158336_k127_863006_0 236097.ADG881_2494 3.406e-95 319.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales 135619|Oceanospirillales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04691,ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 SRR25158336_k127_863006_1 1298593.TOL_3644 2.132e-54 201.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales 135619|Oceanospirillales D COG1192 ATPases involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA SRR25158336_k127_87285_2 1279017.AQYJ01000021_gene2941 2.765e-60 211.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,465DM@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - iECW_1372.ECW_m3896,iEKO11_1354.EKO11_0103,iPC815.YPO0059,iWFL_1372.ECW_m3896 Aminotran_1_2 SRR25158336_k127_87285_0 523791.Kkor_0135 4.723e-151 484.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1XIGQ@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N SRR25158336_k127_87285_1 716541.ECL_03816 2.412e-137 444.0 COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 SRR25158336_k127_87383_1 1049564.TevJSym_aa01440 8.221e-50 181.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SBMS@1236|Gammaproteobacteria,1JBHM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin SRR25158336_k127_87383_2 1049564.TevJSym_aa01430 3.395e-37 151.0 2C7AT@1|root,338A4@2|Bacteria,1NF74@1224|Proteobacteria,1SRBB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_87383_0 511062.GU3_14130 4.8e-168 533.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1Y41H@135624|Aeromonadales 135624|Aeromonadales F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase SRR25158336_k127_875593_2 247633.GP2143_13531 2.104e-100 330.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1J4YR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EH COG0512 Anthranilate para-aminobenzoate synthases component II pabA GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135 GATase SRR25158336_k127_875593_4 314345.SPV1_00512 4.218e-18 84.0 2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_875593_0 1121935.AQXX01000117_gene5092 2.316e-222 699.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBT@135619|Oceanospirillales 135619|Oceanospirillales E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind SRR25158336_k127_875593_1 1049564.TevJSym_ag00460 1.614e-105 346.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6IW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G HAD-hyrolase-like gph GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756 HAD_2 SRR25158336_k127_875593_3 322710.Avin_46660 2.864e-26 108.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0155,iYL1228.KPN_03757 Ribul_P_3_epim SRR25158336_k127_887862_1 1265503.KB905160_gene2729 3.658e-42 161.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator oruR - - - - - - - - - - - Arabinose_bd,HTH_18 SRR25158336_k127_887862_0 1249627.D779_4060 3.648e-202 644.0 COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,1SX9U@1236|Gammaproteobacteria,1X0R6@135613|Chromatiales 135613|Chromatiales U Predicted Permease Membrane Region - - - - - - - - - - - - Asp-Al_Ex,TrkA_C SRR25158336_k127_887862_2 395965.Msil_1087 8.406e-08 56.0 COG4520@1|root,COG4520@2|Bacteria,1N1T9@1224|Proteobacteria,2UCN2@28211|Alphaproteobacteria,3NBGM@45404|Beijerinckiaceae 28211|Alphaproteobacteria M 17 kDa outer membrane surface antigen MA20_07440 - - - - - - - - - - - 17kDa_Anti_2 SRR25158336_k127_888223_2 420662.Mpe_A1032 1.072e-07 59.0 2CEXV@1|root,32S0S@2|Bacteria,1MZKB@1224|Proteobacteria,2VU8J@28216|Betaproteobacteria,1KMC0@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Type II secretion system protein B gspB - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB SRR25158336_k127_888223_0 1163617.SCD_n02200 1.417e-132 442.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria 28216|Betaproteobacteria U SMART AAA ATPase exeA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 SRR25158336_k127_888223_1 870187.Thini_2003 1.079e-09 63.0 COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S alpha beta - - - - - - - - - - - - DUF3530 SRR25158336_k127_906630_1 870187.Thini_4244 5.541e-55 195.0 COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RMCU@1236|Gammaproteobacteria,461XW@72273|Thiotrichales 72273|Thiotrichales H Cobyrinic acid A,C-diamide - - 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 - - - CbiA,GATase_3 SRR25158336_k127_906630_2 1255043.TVNIR_0847 2.069e-28 117.0 COG0316@1|root,COG0316@2|Bacteria,1RKPC@1224|Proteobacteria,1SB76@1236|Gammaproteobacteria,1WYKT@135613|Chromatiales 135613|Chromatiales S Belongs to the HesB IscA family - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SRR25158336_k127_906630_0 870187.Thini_4246 3.707e-85 301.0 COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07673 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HisKA_3 SRR25158336_k127_906630_3 1123400.KB904780_gene1903 6.944e-10 61.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,462II@72273|Thiotrichales 72273|Thiotrichales T helix_turn_helix, Lux Regulon - - - ko:K07684 ko02020,map02020 M00471 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg SRR25158336_k127_909172_4 1123393.KB891316_gene1349 1.115e-47 175.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KRHF@119069|Hydrogenophilales 119069|Hydrogenophilales P Putative metal-binding domain of cation transport ATPase - - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase SRR25158336_k127_909172_6 1121943.KB899989_gene3364 1.108e-13 77.0 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,1XMBA@135619|Oceanospirillales 135619|Oceanospirillales P Cytochrome oxidase maturation protein - - - - - - - - - - - - FixS SRR25158336_k127_909172_5 83406.HDN1F_14200 1.316e-15 78.0 2EH9I@1|root,33B1E@2|Bacteria,1NH43@1224|Proteobacteria,1SD9Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2788) - - - - - - - - - - - - DUF2788 SRR25158336_k127_909172_9 1403313.AXBR01000008_gene522 5.694e-09 61.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,1ZGZX@1386|Bacillus 91061|Bacilli P COG0607 Rhodanese-related sulfurtransferase yqhL - - - - - - - - - - - Rhodanese SRR25158336_k127_909172_8 1166948.JPZL01000001_gene1933 4.691e-11 66.0 COG2885@1|root,COG2885@2|Bacteria,1RGHU@1224|Proteobacteria,1S5H8@1236|Gammaproteobacteria,1XR3B@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA,TSP_3 SRR25158336_k127_909172_0 396588.Tgr7_0365 6.2e-58 203.0 COG2920@1|root,COG2920@2|Bacteria 2|Bacteria P part of a sulfur-relay system - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC SRR25158336_k127_909172_3 545264.KB898749_gene56 2.417e-49 179.0 COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,1S5V4@1236|Gammaproteobacteria,1WYBY@135613|Chromatiales 135613|Chromatiales L PFAM HNH endonuclease - - - - - - - - - - - - HNH SRR25158336_k127_909172_2 298386.PBPRA1267 1.751e-49 184.0 COG4520@1|root,COG4520@2|Bacteria,1PCU5@1224|Proteobacteria,1S861@1236|Gammaproteobacteria 1236|Gammaproteobacteria M surface antigen - - - - - - - - - - - - 17kDa_Anti_2 SRR25158336_k127_909172_1 1278307.KB906975_gene1912 1.556e-49 185.0 COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,1S48A@1236|Gammaproteobacteria,2QI2W@267894|Psychromonadaceae 1236|Gammaproteobacteria J SpoU rRNA Methylase family IV02_28330 - - - - - - - - - - - SpoU_methylase SRR25158336_k127_910930_2 396588.Tgr7_1122 6.207e-32 126.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria,1X1DX@135613|Chromatiales 135613|Chromatiales M 17 kDa outer membrane surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti SRR25158336_k127_910930_1 1123073.KB899241_gene3114 4.715e-75 259.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales 135614|Xanthomonadales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 SRR25158336_k127_910930_0 713586.KB900536_gene2176 7.057e-192 606.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1WVUW@135613|Chromatiales 135613|Chromatiales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC SRR25158336_k127_921030_0 243233.MCA1976 1.68e-294 921.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XE70@135618|Methylococcales 135618|Methylococcales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 SRR25158336_k127_921030_1 1265313.HRUBRA_01624 1.421e-76 263.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind SRR25158336_k127_924020_1 1173264.KI913949_gene2863 9.412e-79 267.0 COG1451@1|root,COG1451@2|Bacteria,1G4YB@1117|Cyanobacteria,1HDXD@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 SRR25158336_k127_924020_2 272123.Anacy_5128 1.314e-27 115.0 COG5606@1|root,COG5606@2|Bacteria,1G845@1117|Cyanobacteria,1HU71@1161|Nostocales 1117|Cyanobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 SRR25158336_k127_924020_3 1173023.KE650771_gene51 0.0001254 46.0 COG4679@1|root,COG4679@2|Bacteria,1G675@1117|Cyanobacteria 1117|Cyanobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 SRR25158336_k127_924020_0 1415754.JQMK01000002_gene3065 1.269e-122 399.0 COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,46451@72275|Alteromonadaceae 1236|Gammaproteobacteria DT COG1718 Serine threonine protein kinase involved in cell cycle control IV02_22125 - 2.7.11.1 ko:K07178 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko01001,ko03009 - - - RIO1 SRR25158336_k127_929650_9 395493.BegalDRAFT_2442 1.845e-21 102.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,462ER@72273|Thiotrichales 72273|Thiotrichales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL SRR25158336_k127_929650_2 395493.BegalDRAFT_3088 1.217e-72 256.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,460PF@72273|Thiotrichales 72273|Thiotrichales U Type II secretion system (T2SS), protein K - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK SRR25158336_k127_929650_5 1123257.AUFV01000001_gene1927 1.762e-46 178.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1X777@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretion system (T2SS), protein J - - - - - - - - - - - - N_methyl,T2SSJ SRR25158336_k127_929650_7 1033802.SSPSH_003283 6.782e-27 114.0 COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria 1224|Proteobacteria NU General secretion pathway protein I gspI GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI SRR25158336_k127_929650_10 1195246.AGRI_11807 1.416e-18 93.0 COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,4672W@72275|Alteromonadaceae 1236|Gammaproteobacteria U general secretion pathway protein gspH GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl SRR25158336_k127_929650_4 1049564.TevJSym_av00280 8.043e-59 209.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1J6D2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U general secretion pathway protein gspG GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG SRR25158336_k127_929650_6 765910.MARPU_01285 5.866e-37 146.0 2B7TJ@1|root,32102@2|Bacteria,1RHKS@1224|Proteobacteria,1S7PY@1236|Gammaproteobacteria,1WYNN@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF5063) - - - - - - - - - - - - DUF5063 SRR25158336_k127_929650_8 765910.MARPU_01280 5.847e-26 107.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria,1WZ6V@135613|Chromatiales 135613|Chromatiales C PFAM Rubredoxin-type Fe(Cys)4 protein - - - - - - - - - - - - Rubredoxin SRR25158336_k127_929650_1 396588.Tgr7_2419 6.258e-103 342.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1WXAI@135613|Chromatiales 135613|Chromatiales H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin SRR25158336_k127_929650_3 1049564.TevJSym_as00130 1.926e-61 218.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1J6HM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI SRR25158336_k127_929650_0 1123517.JOMR01000001_gene1461 4.729e-202 640.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales 72273|Thiotrichales H PFAM aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SRR25158336_k127_930394_3 1198232.CYCME_2426 2.534e-48 178.0 COG4659@1|root,COG4659@2|Bacteria,1MZVX@1224|Proteobacteria,1S9KJ@1236|Gammaproteobacteria,46102@72273|Thiotrichales 72273|Thiotrichales C FMN_bind - - - - - - - - - - - - FMN_bind SRR25158336_k127_930394_0 1411685.U062_01061 1.051e-120 400.0 COG3203@1|root,COG3203@2|Bacteria,1R5I5@1224|Proteobacteria,1RM86@1236|Gammaproteobacteria,1J7SJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M phosphate-selective porin O and P - - - - - - - - - - - - Porin_4,Porin_O_P SRR25158336_k127_930394_4 1198232.CYCME_2424 1.375e-36 141.0 COG0316@1|root,COG0316@2|Bacteria,1RFIX@1224|Proteobacteria,1S3SB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the HesB IscA family - - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn SRR25158336_k127_930394_1 1469245.JFBG01000021_gene1196 7.441e-105 356.0 COG0151@1|root,COG0151@2|Bacteria,1QTYI@1224|Proteobacteria 1224|Proteobacteria F ATP-grasp domain - - - - - - - - - - - - ATP-grasp_4 SRR25158336_k127_930394_5 1198232.CYCME_2423 3.085e-33 131.0 COG2924@1|root,COG2924@2|Bacteria,1QSXN@1224|Proteobacteria,1SS8K@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Bacterial Fe(2+) trafficking - - - - - - - - - - - - Iron_traffic SRR25158336_k127_930394_2 686340.Metal_2805 2.327e-50 183.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1XF45@135618|Methylococcales 135618|Methylococcales S PFAM Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 SRR25158336_k127_930394_6 519989.ECTPHS_02364 1.376e-11 66.0 COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1X1I8@135613|Chromatiales 135613|Chromatiales CO Glutathione peroxidase - - - - - - - - - - - - AhpC-TSA,Redoxin SRR25158336_k127_936697_0 243233.MCA1455 5.514e-126 421.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XEJC@135618|Methylococcales 135618|Methylococcales M Transfers the fatty acyl group on membrane lipoproteins - - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase SRR25158336_k127_936697_1 105559.Nwat_0338 1.774e-62 218.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales 135613|Chromatiales P PFAM CBS domain - - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC SRR25158336_k127_941469_0 1267535.KB906767_gene4458 1.292e-143 477.0 COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia 204432|Acidobacteriia O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH SRR25158336_k127_941469_3 296587.XP_002505596.1 3.975e-07 53.0 COG3450@1|root,2S172@2759|Eukaryota,37VCB@33090|Viridiplantae,34II9@3041|Chlorophyta 3041|Chlorophyta S Protein of unknown function (DUF861) - - - ko:K06995 - - - - ko00000 - - - Cupin_3 SRR25158336_k127_941469_4 1269813.ATUL01000031_gene1403 5.539e-07 52.0 COG3450@1|root,COG3450@2|Bacteria,1N4VS@1224|Proteobacteria,1SC4C@1236|Gammaproteobacteria,1WYPY@135613|Chromatiales 135613|Chromatiales S Ethanolamine utilisation protein EutQ - - - ko:K06995 - - - - ko00000 - - - Cupin_3 SRR25158336_k127_941469_2 243233.MCA1531 2.269e-18 89.0 2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,1SCCQ@1236|Gammaproteobacteria,1XFTW@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 SRR25158336_k127_941469_1 765911.Thivi_1808 5.51e-72 247.0 COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1WWHE@135613|Chromatiales 135613|Chromatiales L hydrolase, TatD family - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SRR25158336_k127_950717_10 105559.Nwat_1839 4.672e-28 119.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2066) - - - ko:K09938 - - - - ko00000 - - - DUF2066 SRR25158336_k127_950717_3 1026882.MAMP_02028 1.831e-158 507.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4600E@72273|Thiotrichales 72273|Thiotrichales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SRR25158336_k127_950717_6 472759.Nhal_0872 1.295e-81 277.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1WY1C@135613|Chromatiales 135613|Chromatiales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N SRR25158336_k127_950717_9 1260251.SPISAL_02520 2.492e-33 139.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 SRR25158336_k127_950717_4 375286.mma_1184 2.416e-113 366.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,4728N@75682|Oxalobacteraceae 28216|Betaproteobacteria F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase SRR25158336_k127_950717_2 2340.JV46_06490 5.063e-176 559.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1J4F3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SRR25158336_k127_950717_0 207954.MED92_14453 0.0 1020.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XHBT@135619|Oceanospirillales 135619|Oceanospirillales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind SRR25158336_k127_950717_5 396588.Tgr7_2626 3.287e-92 306.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WX8K@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr SRR25158336_k127_950717_7 396588.Tgr7_2627 8.52e-80 276.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1WY08@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 SRR25158336_k127_950717_1 713586.KB900536_gene2721 2.694e-184 592.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB SRR25158336_k127_950717_8 105559.Nwat_1853 3.327e-49 179.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE SRR25158336_k127_956590_0 519989.ECTPHS_07331 0.0 1102.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales 135613|Chromatiales C Dehydrogenase E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr SRR25158336_k127_956590_1 396588.Tgr7_0078 1.884e-33 132.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1WXGA@135613|Chromatiales 135613|Chromatiales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding SRR25158336_k127_963787_4 870187.Thini_4285 2.402e-34 133.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 SRR25158336_k127_963787_5 2340.JV46_05640 1.888e-23 100.0 2C7TU@1|root,32RJT@2|Bacteria,1N2CD@1224|Proteobacteria,1S96C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_963787_2 768671.ThimaDRAFT_3400 1.159e-42 162.0 28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,1RS8I@1236|Gammaproteobacteria,1WWZ9@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_963787_0 870187.Thini_1163 2.342e-114 379.0 2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,1RPSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_963787_1 631362.Thi970DRAFT_04215 1.459e-91 304.0 COG3751@1|root,COG3751@2|Bacteria,1RBXB@1224|Proteobacteria,1RR8W@1236|Gammaproteobacteria,1WWUG@135613|Chromatiales 135613|Chromatiales O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 SRR25158336_k127_963787_3 1129374.AJE_12418 5.372e-36 144.0 COG1246@1|root,COG1246@2|Bacteria,1QVUT@1224|Proteobacteria,1T2JM@1236|Gammaproteobacteria,46D7W@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,YiiD_C SRR25158336_k127_963787_6 765913.ThidrDRAFT_3349 3.951e-11 64.0 28QMK@1|root,2ZD39@2|Bacteria,1RAWM@1224|Proteobacteria,1S2FU@1236|Gammaproteobacteria,1WY0Y@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - SRR25158336_k127_976712_1 338966.Ppro_1537 9.184e-06 55.0 COG0810@1|root,COG0810@2|Bacteria,1N94H@1224|Proteobacteria,42V43@68525|delta/epsilon subdivisions,2WRRA@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C SRR25158336_k127_976712_0 1049564.TevJSym_ad00670 1.768e-85 293.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J4YK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG4206 Outer membrane cobalamin receptor protein btuB GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - iECB_1328.ECB_03851,iECP_1309.ECP_4183,iSF_1195.SF4048,iS_1188.S3696 Plug,TonB_dep_Rec SRR25158336_k127_981468_0 1499686.BN1079_02974 6.175e-117 391.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 SRR25158336_k127_981468_1 1168067.JAGP01000001_gene1912 2.959e-19 88.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,45ZVT@72273|Thiotrichales 72273|Thiotrichales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b SRR25158336_k127_984782_1 472759.Nhal_2360 1.651e-82 279.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG SRR25158336_k127_984782_0 472759.Nhal_0594 2.004e-111 368.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales 135613|Chromatiales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P SRR25158336_k127_984782_3 941449.dsx2_1337 6.769e-07 56.0 2DSEB@1|root,33FSP@2|Bacteria,1NIVA@1224|Proteobacteria,42WUP@68525|delta/epsilon subdivisions,2WSP5@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF3106) - - - - - - - - - - - - DUF3106 SRR25158336_k127_984782_4 1163408.UU9_01959 0.0001691 51.0 2A0FJ@1|root,30NJD@2|Bacteria,1QBAA@1224|Proteobacteria,1T6UX@1236|Gammaproteobacteria,1X87D@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SRR25158336_k127_984782_2 1123368.AUIS01000005_gene375 1.769e-34 140.0 COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,1SA30@1236|Gammaproteobacteria,2ND7J@225057|Acidithiobacillales 225057|Acidithiobacillales K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r4_2 SRR25158336_k127_984843_3 765910.MARPU_13705 1.696e-25 107.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria,1WXZR@135613|Chromatiales 135613|Chromatiales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese SRR25158336_k127_984843_0 395493.BegalDRAFT_1825 2.792e-84 289.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,4612J@72273|Thiotrichales 72273|Thiotrichales M Lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SRR25158336_k127_984843_2 768671.ThimaDRAFT_1995 2.174e-26 116.0 COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria,1T4CE@1236|Gammaproteobacteria,1X1B8@135613|Chromatiales 135613|Chromatiales S Tetratricopeptide repeat - - - - - - - - - - - - - SRR25158336_k127_984843_1 765914.ThisiDRAFT_2159 1.711e-60 211.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH SRR25158336_k127_988200_0 396588.Tgr7_2295 1.826e-273 849.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SRR25158336_k127_988200_2 420324.KI911972_gene2998 5.703e-79 270.0 COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2TVNY@28211|Alphaproteobacteria 28211|Alphaproteobacteria S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans SRR25158336_k127_988200_4 1049564.TevJSym_aq00510 1.21e-25 110.0 2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,1SEFI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SRR25158336_k127_988200_3 555778.Hneap_1706 3.65e-35 136.0 COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,1SAV8@1236|Gammaproteobacteria,1WZPV@135613|Chromatiales 135613|Chromatiales S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP SRR25158336_k127_988200_1 1163407.UU7_11265 4.937e-130 436.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,1X53W@135614|Xanthomonadales 135614|Xanthomonadales S L,D-transpeptidase catalytic domain - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD SRR25158336_k127_988200_5 1496688.ER33_12165 0.0006191 46.0 COG0438@1|root,COG0438@2|Bacteria,1GA3P@1117|Cyanobacteria,22TYE@167375|Cyanobium 1117|Cyanobacteria M Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 SRR25158336_k127_994032_1 448385.sce5230 9.867e-38 146.0 COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,43157@68525|delta/epsilon subdivisions,2WWIW@28221|Deltaproteobacteria,2YVGQ@29|Myxococcales 28221|Deltaproteobacteria Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 SRR25158336_k127_994032_0 391625.PPSIR1_03323 2.985e-118 388.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2X5YA@28221|Deltaproteobacteria,2YUMQ@29|Myxococcales 28221|Deltaproteobacteria S Nitronate monooxygenase - - 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO SRR25158336_k127_994032_3 1123368.AUIS01000005_gene353 6.137e-10 61.0 28XT8@1|root,2ZJPP@2|Bacteria,1P53A@1224|Proteobacteria,1SVUA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF3330) - - - - - - - - - - - - DUF3330 SRR25158336_k127_994032_2 104623.Ser39006_00873 5.078e-16 79.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,401Z8@613|Serratia 1236|Gammaproteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 SRR25158336_k127_996872_1 768671.ThimaDRAFT_3216 2.022e-118 386.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1WX1H@135613|Chromatiales 135613|Chromatiales E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth SRR25158336_k127_996872_0 713586.KB900536_gene1899 1.764e-197 634.0 COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1WWBM@135613|Chromatiales 135613|Chromatiales E Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N SRR25158336_k127_996872_3 472759.Nhal_1873 1.223e-94 319.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1WXUX@135613|Chromatiales 135613|Chromatiales I 6-phosphogluconate dehydrogenase, NAD-binding - - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 SRR25158336_k127_996872_5 1121403.AUCV01000005_gene207 3.924e-17 87.0 COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,42TT9@68525|delta/epsilon subdivisions 1224|Proteobacteria O methyltransferase - - - - - - - - - - - - ICMT,PEMT SRR25158336_k127_996872_6 1121403.AUCV01000005_gene207 2.076e-09 58.0 COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,42TT9@68525|delta/epsilon subdivisions 1224|Proteobacteria O methyltransferase - - - - - - - - - - - - ICMT,PEMT SRR25158336_k127_996872_4 296591.Bpro_1663 3.466e-48 176.0 COG1917@1|root,COG1917@2|Bacteria,1MZFB@1224|Proteobacteria 1224|Proteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 SRR25158336_k127_996872_2 1168065.DOK_06452 5.599e-105 347.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P membrane protein, terc ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - TerC SRR25158336_k127_996872_7 566466.NOR53_479 5.437e-06 53.0 29GUQ@1|root,2ZIQ9@2|Bacteria,1P89M@1224|Proteobacteria,1STDV@1236|Gammaproteobacteria,1JBAC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 SRR25158336_k127_998793_1 349521.HCH_05886 4.72e-45 164.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1XIQQ@135619|Oceanospirillales 135619|Oceanospirillales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 SRR25158336_k127_998793_0 1049564.TevJSym_aj00320 5.135e-137 447.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1J5GI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097 Mur_ligase_C,Mur_ligase_M ## 1575 queries scanned ## Total time (seconds): 4.624313831329346 ## Rate: 340.59 q/s