## Sun Dec 14 02:24:55 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158338_bin.13.fa -m mmseqs --itype genome -o SRR25158338_bin.13 --output_dir /data/result/bins/wyx/egg/SRR25158338_bin.13 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158338_k127_1003568_10	1313172.YM304_38800	4.838e-12	70.0	COG0344@1|root,COG0344@2|Bacteria,2IFX1@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158338_k127_1003568_7	455632.SGR_4975	9.764e-36	149.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,41943@629295|Streptomyces griseus group	201174|Actinobacteria	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158338_k127_1003568_1	237368.SCABRO_01822	6.105e-99	340.0	COG1249@1|root,COG1249@2|Bacteria,2IYD2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158338_k127_1003568_6	1279017.AQYJ01000024_gene1153	4.817e-38	145.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria,46BQS@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158338_k127_1003568_0	68570.DC74_564	4.247e-107	362.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158338_k127_1003568_8	1121920.AUAU01000018_gene1775	1.7e-17	84.0	COG2318@1|root,COG2318@2|Bacteria,3Y4HW@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158338_k127_1003568_2	255470.cbdbA715	2.68e-81	279.0	COG0253@1|root,COG0253@2|Bacteria,2G99B@200795|Chloroflexi,34CPD@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158338_k127_1003568_9	479434.Sthe_1767	1.43e-15	87.0	COG1277@1|root,COG1277@2|Bacteria,2GBGK@200795|Chloroflexi,27YD7@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158338_k127_1003568_3	266117.Rxyl_0089	2.291e-68	243.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4CS0Z@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158338_k127_1003568_5	485913.Krac_2249	1.212e-53	195.0	COG0645@1|root,COG0645@2|Bacteria,2G9N6@200795|Chloroflexi	200795|Chloroflexi	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1003568_4	357808.RoseRS_3334	3.65e-67	237.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158338_k127_1149751_37	1120971.AUCA01000047_gene853	6.614e-35	146.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M15_4
SRR25158338_k127_1149751_7	562970.Btus_1285	7.657e-106	355.0	COG1063@1|root,COG1063@2|Bacteria,1U5GN@1239|Firmicutes,4HDDV@91061|Bacilli	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158338_k127_1149751_11	1333998.M2A_2579	4.557e-94	321.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2TRSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amidohydrolase	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158338_k127_1149751_15	1394178.AWOO02000076_gene1929	8.533e-87	297.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158338_k127_1149751_2	1382306.JNIM01000001_gene3950	1.053e-193	646.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158338_k127_1149751_18	688269.Theth_1476	2.491e-80	289.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158338_k127_1149751_13	1382356.JQMP01000003_gene1699	7.031e-89	308.0	COG1820@1|root,COG1820@2|Bacteria,2G6HC@200795|Chloroflexi,27XRA@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158338_k127_1149751_12	926550.CLDAP_35910	2.175e-90	305.0	COG2521@1|root,COG2521@2|Bacteria,2G7RX@200795|Chloroflexi	200795|Chloroflexi	S	Methyltransferase domain	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11
SRR25158338_k127_1149751_32	1463936.JOJI01000024_gene1260	8.703e-53	205.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158338_k127_1149751_34	1121468.AUBR01000024_gene3037	4.208e-38	153.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	QU41_16170	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S15
SRR25158338_k127_1149751_47	402626.Rpic_3158	2.168e-16	81.0	COG3369@1|root,COG3369@2|Bacteria,1NMEB@1224|Proteobacteria,2VXWW@28216|Betaproteobacteria,1K9XN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158338_k127_1149751_28	525904.Tter_1368	2.92e-61	217.0	COG0461@1|root,COG0461@2|Bacteria,2NPFJ@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158338_k127_1149751_35	326427.Cagg_1653	6.377e-38	154.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,375E7@32061|Chloroflexia	32061|Chloroflexia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158338_k127_1149751_33	357808.RoseRS_4389	4.357e-51	190.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158338_k127_1149751_56	317619.ANKN01000118_gene3024	0.0001195	54.0	COG2968@1|root,COG2968@2|Bacteria,1GA0H@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
SRR25158338_k127_1149751_24	675635.Psed_6571	4.966e-66	232.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4DZAX@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158338_k127_1149751_53	1121405.dsmv_3079	1.928e-08	64.0	COG0500@1|root,COG2226@2|Bacteria,1QU24@1224|Proteobacteria,43BNY@68525|delta/epsilon subdivisions,2X70A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158338_k127_1149751_20	485913.Krac_7924	1.637e-70	256.0	COG2318@1|root,COG2318@2|Bacteria,2G8NT@200795|Chloroflexi	200795|Chloroflexi	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158338_k127_1149751_9	552811.Dehly_0516	3.229e-96	329.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2G5SW@200795|Chloroflexi,34CN3@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158338_k127_1149751_49	1207075.PputUW4_04285	4.774e-13	75.0	COG1714@1|root,COG1714@2|Bacteria,1N7R6@1224|Proteobacteria,1SCCT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158338_k127_1149751_54	1463861.JNXE01000038_gene3543	9.638e-07	58.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158338_k127_1149751_46	1492922.GY26_10070	1.261e-17	95.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158338_k127_1149751_27	1128421.JAGA01000002_gene1632	3.878e-62	241.0	COG1276@1|root,COG2010@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2010@2|Bacteria,COG2372@2|Bacteria,2NPS1@2323|unclassified Bacteria	2|Bacteria	P	Evidence 5 No homology to any previously reported sequences	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD,Cytochrome_CBB3,YtkA
SRR25158338_k127_1149751_23	1449353.JQMQ01000004_gene6252	3.403e-67	237.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_1149751_5	1394178.AWOO02000001_gene1514	4.018e-129	423.0	COG0183@1|root,COG0183@2|Bacteria,2IBJU@201174|Actinobacteria	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158338_k127_1149751_41	1227360.C176_11559	2.334e-22	107.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4HCP5@91061|Bacilli,26F1P@186818|Planococcaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158338_k127_1149751_8	383372.Rcas_3959	5.101e-98	331.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_1149751_36	1121272.KB903250_gene2872	1.29e-37	157.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria,4DIAN@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158338_k127_1149751_14	1144275.COCOR_05071	1.34e-88	311.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158338_k127_1149751_26	383372.Rcas_1392	6.666e-64	225.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi,375EY@32061|Chloroflexia	32061|Chloroflexia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158338_k127_1149751_4	1382356.JQMP01000003_gene1994	1.024e-131	434.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158338_k127_1149751_6	309801.trd_1226	1.512e-116	388.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,27XF5@189775|Thermomicrobia	189775|Thermomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158338_k127_1149751_39	479434.Sthe_1420	3.538e-31	128.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,27YCZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158338_k127_1149751_0	552811.Dehly_0551	2.985e-232	730.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,34D3I@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158338_k127_1149751_16	552811.Dehly_0550	9.15e-84	286.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi,34CV9@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158338_k127_1149751_1	525904.Tter_0065	1.223e-217	685.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158338_k127_1149751_48	485913.Krac_5906	1.823e-13	77.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
SRR25158338_k127_1149751_42	1410618.JNKI01000007_gene762	9.446e-22	102.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4H4CM@909932|Negativicutes	909932|Negativicutes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158338_k127_1149751_43	479434.Sthe_1425	1.541e-21	101.0	COG0711@1|root,COG0711@2|Bacteria,2G76T@200795|Chloroflexi,27YGB@189775|Thermomicrobia	189775|Thermomicrobia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158338_k127_1149751_45	485913.Krac_8499	3.667e-18	87.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158338_k127_1149751_30	243164.DET0558	7.244e-59	217.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,34D35@301297|Dehalococcoidia	301297|Dehalococcoidia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158338_k127_1149751_51	311424.DhcVS_496	2.439e-09	61.0	2BPKF@1|root,32IDF@2|Bacteria,2GAWX@200795|Chloroflexi,34DI2@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
SRR25158338_k127_1149751_25	552811.Dehly_0789	1.507e-65	228.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,34DAC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158338_k127_1149751_50	682795.AciX8_4378	8.172e-13	81.0	COG0477@1|root,COG2814@2|Bacteria,3Y2VT@57723|Acidobacteria,2JIIT@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_1149751_44	479434.Sthe_0412	7.47e-20	95.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
SRR25158338_k127_1149751_17	485913.Krac_10511	1.147e-80	278.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158338_k127_1149751_38	1303518.CCALI_02619	1.396e-31	134.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158338_k127_1149751_31	552811.Dehly_0968	7.242e-55	201.0	COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi	200795|Chloroflexi	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158338_k127_1149751_22	56780.SYN_02637	1.528e-68	245.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MR3X@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158338_k127_1149751_40	1382306.JNIM01000001_gene2847	7.939e-27	115.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158338_k127_1149751_55	404589.Anae109_0978	9.259e-05	53.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2WQ9A@28221|Deltaproteobacteria,2YVEF@29|Myxococcales	28221|Deltaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158338_k127_1149751_10	671143.DAMO_1145	5.455e-96	327.0	COG3842@1|root,COG3842@2|Bacteria,2NNPE@2323|unclassified Bacteria	2|Bacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	gtsA	-	3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55	ko:K02010,ko:K02045,ko:K02049,ko:K02068,ko:K02071,ko:K06857,ko:K10112,ko:K11072	ko00920,ko02010,map00920,map02010	M00185,M00186,M00188,M00190,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00211,M00238,M00299,M00491,M00602,M00605,M00606	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.10,3.A.1.11.1,3.A.1.16,3.A.1.17,3.A.1.24,3.A.1.6.1,3.A.1.6.2,3.A.1.6.3,3.A.1.6.4	-	-	ABC_tran,TOBE_2
SRR25158338_k127_1149751_21	767817.Desgi_1310	1.702e-69	244.0	COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,249VG@186801|Clostridia,260GI@186807|Peptococcaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
SRR25158338_k127_1149751_29	643648.Slip_1758	5.488e-59	216.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,42JT0@68298|Syntrophomonadaceae	186801|Clostridia	H	ABC-type tungstate transport system permease component-like protein	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
SRR25158338_k127_1149751_3	479434.Sthe_2136	1.718e-140	465.0	COG0477@1|root,COG0477@2|Bacteria,2G5X2@200795|Chloroflexi,27ZD8@189775|Thermomicrobia	189775|Thermomicrobia	P	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_1149751_52	1120972.AUMH01000004_gene1508	5.181e-09	64.0	COG1846@1|root,COG1846@2|Bacteria,1TTMJ@1239|Firmicutes,4IGAV@91061|Bacilli,27A1D@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158338_k127_1149751_19	91464.S7335_3904	1.048e-74	265.0	COG1565@1|root,COG1565@2|Bacteria,1G16Z@1117|Cyanobacteria,1GYBU@1129|Synechococcus	1117|Cyanobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158338_k127_1165324_4	926550.CLDAP_22950	3.637e-75	261.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR25158338_k127_1165324_6	926569.ANT_30540	4.692e-51	197.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1165324_1	479434.Sthe_2502	8.703e-166	547.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158338_k127_1165324_2	1128421.JAGA01000002_gene1247	1.053e-115	403.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158338_k127_1165324_5	926569.ANT_00470	1.981e-59	214.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158338_k127_1165324_7	926550.CLDAP_11180	1.504e-23	110.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158338_k127_1165324_0	485913.Krac_7601	3.376e-184	587.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158338_k127_1165324_3	479434.Sthe_1797	4.344e-84	296.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi,27XSK@189775|Thermomicrobia	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158338_k127_1165324_8	635013.TherJR_2930	1.245e-08	58.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,260HH@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158338_k127_1167288_2	926554.KI912672_gene16	1.034e-62	228.0	COG1063@1|root,COG1063@2|Bacteria,1WMH7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158338_k127_1167288_1	402881.Plav_3077	2.875e-88	302.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria,2U25T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1167288_0	402881.Plav_3076	1.909e-94	320.0	COG3173@1|root,COG3173@2|Bacteria,1MY0Y@1224|Proteobacteria,2TRMW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Aminoglycoside phosphotransferase	MA20_16375	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158338_k127_1167288_3	44454.NF84_18410	3.025e-11	72.0	COG3173@1|root,COG3173@2|Bacteria,2IQRM@201174|Actinobacteria,23AJ7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1169040_1	272134.KB731324_gene1700	3.769e-72	249.0	COG0535@1|root,COG0535@2|Bacteria,1G1TV@1117|Cyanobacteria,1H8N1@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
SRR25158338_k127_1169040_2	1123023.JIAI01000003_gene3097	4.05e-65	237.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4DX7Q@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA1	GO:0000287,GO:0003674,GO:0003824,GO:0004161,GO:0004659,GO:0005488,GO:0005506,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0030145,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045337,GO:0045338,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158338_k127_1169040_4	479434.Sthe_2006	3.339e-40	155.0	COG0432@1|root,COG1304@1|root,COG0432@2|Bacteria,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158338_k127_1169040_0	882083.SacmaDRAFT_2674	4.618e-97	337.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria,4E1XZ@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM squalene-associated FAD-dependent desaturase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158338_k127_1169040_3	671143.DAMO_1512	5.853e-64	229.0	COG1562@1|root,COG1562@2|Bacteria,2NQ19@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158338_k127_1169040_5	1449346.JQMO01000003_gene6926	5.244e-16	81.0	COG1562@1|root,COG1562@2|Bacteria,2GNS9@201174|Actinobacteria,2M17X@2063|Kitasatospora	201174|Actinobacteria	I	Squalene/phytoene synthase	hopE	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR25158338_k127_1188027_12	309801.trd_0753	1.001e-33	133.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi,27Y3Y@189775|Thermomicrobia	189775|Thermomicrobia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158338_k127_1188027_0	867903.ThesuDRAFT_00057	7.045e-177	573.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,3WCD1@538999|Clostridiales incertae sedis	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158338_k127_1188027_1	1449126.JQKL01000017_gene2793	7.957e-137	445.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,268DK@186813|unclassified Clostridiales	186801|Clostridia	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158338_k127_1188027_16	59538.XP_005975644.1	6.187e-05	52.0	COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria	33208|Metazoa	Q	Oxidoreductase activity. It is involved in the biological process described with metabolic process	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158338_k127_1188027_9	43354.JOIJ01000006_gene1923	9.831e-50	187.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4E57Z@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158338_k127_1188027_10	29540.C481_00145	8.982e-42	164.0	COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,23TIB@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158338_k127_1188027_2	797209.ZOD2009_18719	1.186e-89	308.0	COG1814@1|root,arCOG01096@2157|Archaea,2XWEX@28890|Euryarchaeota,241DC@183963|Halobacteria	183963|Halobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158338_k127_1188027_15	52644.XP_010566792.1	1.4e-14	82.0	COG0456@1|root,KOG3139@2759|Eukaryota,39YBU@33154|Opisthokonta,3BR0I@33208|Metazoa,3D7AP@33213|Bilateria,48QZI@7711|Chordata,49MJG@7742|Vertebrata,4GI9Q@8782|Aves	33208|Metazoa	S	Acetyltransferase (GNAT) domain	NAT8B	GO:0001702,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0007162,GO:0007275,GO:0007369,GO:0008150,GO:0009653,GO:0009790,GO:0012505,GO:0030155,GO:0032501,GO:0032502,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048598,GO:0048856,GO:0050789,GO:0050794,GO:0065007	2.3.1.80	ko:K20838	ko00480,map00480	-	R04950	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
SRR25158338_k127_1188027_7	1089550.ATTH01000001_gene2063	7.876e-59	213.0	COG1028@1|root,COG1028@2|Bacteria,4NGR3@976|Bacteroidetes,1FIP0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158338_k127_1188027_8	1147.D082_25660	7.725e-53	209.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
SRR25158338_k127_1188027_5	1117379.BABA_12915	1.771e-60	224.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158338_k127_1188027_11	685727.REQ_31380	1.468e-38	149.0	COG3871@1|root,COG3871@2|Bacteria,2I2QZ@201174|Actinobacteria,4G9FN@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158338_k127_1188027_6	797299.HALLA_16345	7.416e-60	222.0	COG0702@1|root,arCOG03015@2157|Archaea,2XVBX@28890|Euryarchaeota,23U9C@183963|Halobacteria	183963|Halobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158338_k127_1188027_13	1173023.KE650771_gene5511	9.732e-32	136.0	COG0662@1|root,COG0662@2|Bacteria,1GFZG@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158338_k127_1188027_4	485913.Krac_4810	2.569e-69	247.0	COG2141@1|root,COG2141@2|Bacteria,2G8NG@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_1188027_14	644282.Deba_0172	4.419e-16	85.0	2EB22@1|root,3352W@2|Bacteria,1NE0W@1224|Proteobacteria,42VEE@68525|delta/epsilon subdivisions,2WRJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1188027_3	1123504.JQKD01000012_gene1255	8.982e-72	256.0	COG1804@1|root,COG1804@2|Bacteria,1NSWZ@1224|Proteobacteria,2VPQF@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_1194252_1	1125863.JAFN01000001_gene2957	1.684e-153	501.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158338_k127_1194252_5	309799.DICTH_1450	1.316e-16	87.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158338_k127_1194252_4	1237149.C900_00788	9.122e-42	158.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,47QAB@768503|Cytophagia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158338_k127_1194252_0	243164.DET1630	2.478e-280	889.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,34D9E@301297|Dehalococcoidia	301297|Dehalococcoidia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158338_k127_1194252_2	42256.RradSPS_1165	1.027e-133	437.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158338_k127_1194252_3	266117.Rxyl_1174	2.039e-75	261.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158338_k127_127340_9	326424.FRAAL6035	2.493e-40	170.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
SRR25158338_k127_127340_0	1278073.MYSTI_05419	2.207e-105	349.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,437ER@68525|delta/epsilon subdivisions,2X2M0@28221|Deltaproteobacteria,2Z09K@29|Myxococcales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158338_k127_127340_12	1484157.PSNIH2_04690	2.236e-12	72.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,1SANY@1236|Gammaproteobacteria,3W0VD@53335|Pantoea	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158338_k127_127340_11	926550.CLDAP_05380	1.196e-30	126.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158338_k127_127340_5	981369.JQMJ01000004_gene5276	3.452e-72	252.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NJ3P@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158338_k127_127340_1	981369.JQMJ01000004_gene5277	5.184e-96	323.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NFPR@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158338_k127_127340_8	42345.XP_008801228.1	2.936e-42	162.0	COG0054@1|root,KOG3243@2759|Eukaryota,37P3N@33090|Viridiplantae,3GEK9@35493|Streptophyta,3KSWU@4447|Liliopsida	35493|Streptophyta	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Autophagy_act_C,DMRL_synthase
SRR25158338_k127_127340_10	479434.Sthe_1360	1.278e-36	147.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi,27YB6@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158338_k127_127340_7	1009370.ALO_10609	1.877e-43	166.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4H4P0@909932|Negativicutes	909932|Negativicutes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158338_k127_127340_2	644966.Tmar_1263	3.161e-88	306.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158338_k127_127340_4	861299.J421_4276	6.582e-78	271.0	COG0181@1|root,COG0181@2|Bacteria,1ZTQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158338_k127_127340_3	1120985.AUMI01000005_gene2502	1.525e-80	274.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4H32B@909932|Negativicutes	909932|Negativicutes	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158338_k127_127340_6	330214.NIDE2743	5.822e-70	247.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,3J0B6@40117|Nitrospirae	40117|Nitrospirae	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158338_k127_127340_13	102232.GLO73106DRAFT_00013980	3.47e-08	58.0	COG4948@1|root,COG4948@2|Bacteria,1G57H@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
SRR25158338_k127_1282731_3	1283299.AUKG01000003_gene204	3.113e-69	237.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158338_k127_1282731_2	1306174.JODP01000032_gene4027	9.984e-88	314.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158338_k127_1282731_8	111781.Lepto7376_0803	3.535e-05	51.0	COG3011@1|root,COG3011@2|Bacteria,1G8S7@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158338_k127_1282731_6	1254432.SCE1572_11705	4.673e-27	119.0	2E6S9@1|root,331CB@2|Bacteria,1QQT9@1224|Proteobacteria,43E0N@68525|delta/epsilon subdivisions,2X94D@28221|Deltaproteobacteria,2Z1UU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1282731_1	448385.sce1926	9.626e-99	335.0	2B8GZ@1|root,321S2@2|Bacteria,1PMCZ@1224|Proteobacteria,439VN@68525|delta/epsilon subdivisions,2X59R@28221|Deltaproteobacteria,2Z0AZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
SRR25158338_k127_1282731_9	1380356.JNIK01000015_gene2514	0.0006951	52.0	COG3103@1|root,COG5479@1|root,COG4991@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4EX5K@85013|Frankiales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SRR25158338_k127_1282731_0	1121106.JQKB01000083_gene2763	3.73e-126	415.0	COG2141@1|root,COG2141@2|Bacteria,1NKS6@1224|Proteobacteria,2TT87@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	MA20_23445	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158338_k127_1282731_4	909663.KI867150_gene1867	5.816e-49	186.0	COG2047@1|root,COG2047@2|Bacteria,1P1AJ@1224|Proteobacteria,43146@68525|delta/epsilon subdivisions,2WWXB@28221|Deltaproteobacteria,2MS95@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158338_k127_1282731_7	662479.C440_05345	5.93e-11	68.0	arCOG02749@1|root,arCOG02749@2157|Archaea,2Y49A@28890|Euryarchaeota,23ZX0@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1282731_5	216594.MMAR_3587	1.995e-46	177.0	2CK2M@1|root,32SBE@2|Bacteria,2IHIU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1304111_9	395961.Cyan7425_1966	4.006e-37	160.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158338_k127_1304111_4	670487.Ocepr_1975	4.272e-107	367.0	COG1028@1|root,COG1028@2|Bacteria,1WM8P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158338_k127_1304111_1	761193.Runsl_1927	3.815e-192	610.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158338_k127_1304111_6	868131.MSWAN_2143	1.121e-70	248.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,23PFN@183925|Methanobacteria	183925|Methanobacteria	E	SMART ATPase, AAA type, core	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158338_k127_1304111_5	1220534.B655_1263	7.204e-84	291.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,23PE0@183925|Methanobacteria	183925|Methanobacteria	P	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158338_k127_1304111_10	357808.RoseRS_0700	3.305e-11	73.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi,375JI@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1304111_0	243164.DET1281	2.2e-314	1000.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,34CKB@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158338_k127_1304111_8	1286171.EAL2_c02130	1.137e-49	183.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,25W6U@186806|Eubacteriaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158338_k127_1304111_3	383372.Rcas_4262	6.407e-123	406.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,3751V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158338_k127_1304111_2	861299.J421_0396	5.946e-129	424.0	COG1028@1|root,COG1028@2|Bacteria,1ZV1D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158338_k127_1304111_7	861299.J421_0395	2.379e-56	200.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Glutaredoxin
SRR25158338_k127_1320230_2	485913.Krac_1276	3.91e-24	105.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158338_k127_1320230_0	311424.DhcVS_63	1.744e-40	161.0	COG4974@1|root,COG4974@2|Bacteria,2G8U5@200795|Chloroflexi,34DNB@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158338_k127_1320230_1	1288083.AUKR01000014_gene2875	2.111e-24	108.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158338_k127_1329082_0	47839.CCAU010000004_gene892	7.01e-83	283.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158338_k127_1329082_2	591019.Shell_0193	0.0003759	47.0	arCOG04155@1|root,arCOG04155@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1329082_1	479434.Sthe_2824	9.689e-76	258.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi,27Y3J@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158338_k127_1373948_2	243164.DET0059	1.791e-41	157.0	COG1211@1|root,COG1211@2|Bacteria,2G6UP@200795|Chloroflexi,34D6D@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158338_k127_1373948_4	357808.RoseRS_4387	1.871e-13	80.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi,375X7@32061|Chloroflexia	32061|Chloroflexia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158338_k127_1373948_1	1303518.CCALI_00041	3.991e-159	512.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158338_k127_1373948_0	479434.Sthe_1030	0.0	1557.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,27Y0B@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158338_k127_1373948_3	485913.Krac_12535	5.406e-17	82.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158338_k127_1398021_5	1382306.JNIM01000001_gene1358	4.866e-25	105.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158338_k127_1398021_0	195522.BD01_0745	2.525e-70	256.0	COG0534@1|root,arCOG01731@2157|Archaea,2XUU4@28890|Euryarchaeota,242ZQ@183968|Thermococci	183968|Thermococci	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158338_k127_1398021_3	68194.JNXR01000042_gene142	9.152e-33	138.0	COG4689@1|root,COG4689@2|Bacteria,2I8M2@201174|Actinobacteria	201174|Actinobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRR25158338_k127_1398021_1	1211115.ALIQ01000184_gene4159	2.863e-64	239.0	COG0644@1|root,COG0644@2|Bacteria,1QM8G@1224|Proteobacteria,2TV3N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
SRR25158338_k127_1398021_6	1480694.DC28_12460	5.529e-23	105.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K09766,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	DUF2225,HTH_Crp_2,cNMP_binding
SRR25158338_k127_1398021_7	1336249.JADW01000028_gene1027	8.746e-19	96.0	COG2030@1|root,COG2030@2|Bacteria,1NAYM@1224|Proteobacteria,2TRU0@28211|Alphaproteobacteria,4BF2C@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158338_k127_1398021_8	266265.Bxe_C0512	2.62e-11	73.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	maoC	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158338_k127_1398021_9	429009.Adeg_1007	9.573e-08	56.0	COG1977@1|root,COG1977@2|Bacteria,1VIUV@1239|Firmicutes,24RKW@186801|Clostridia,42HDN@68295|Thermoanaerobacterales	186801|Clostridia	H	Mut7-C ubiquitin	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158338_k127_1398021_4	479434.Sthe_1819	1.039e-31	129.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158338_k127_1398021_2	479434.Sthe_1818	1.612e-58	216.0	COG2042@1|root,COG3376@2|Bacteria	2|Bacteria	K	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
SRR25158338_k127_144614_9	479434.Sthe_1582	6.527e-29	122.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158338_k127_144614_3	1382306.JNIM01000001_gene4039	1.944e-78	272.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158338_k127_144614_5	309801.trd_A0395	2.76e-38	156.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158338_k127_144614_11	411468.CLOSCI_00953	5.639e-22	106.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,21ZWZ@1506553|Lachnoclostridium	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158338_k127_144614_8	552811.Dehly_1102	5.787e-35	140.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,34D3G@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158338_k127_144614_10	309801.trd_A0640	6.706e-25	113.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158338_k127_144614_7	525904.Tter_2435	2.762e-37	152.0	COG2340@1|root,COG2340@2|Bacteria,2NRNT@2323|unclassified Bacteria	2|Bacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158338_k127_144614_4	477974.Daud_2231	9.078e-41	161.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,261UV@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158338_k127_144614_13	861299.J421_1645	7.401e-10	68.0	2A4CF@1|root,30SY3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158338_k127_144614_1	298654.FraEuI1c_0833	2.931e-111	368.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4ERJD@85013|Frankiales	201174|Actinobacteria	C	PFAM Luciferase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_144614_0	485913.Krac_3359	1.29e-128	427.0	COG0477@1|root,COG2814@2|Bacteria,2G814@200795|Chloroflexi	2|Bacteria	P	SPTR A9B396 Drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_144614_6	1123023.JIAI01000002_gene4891	1.872e-37	146.0	COG1733@1|root,COG1733@2|Bacteria,2HEVV@201174|Actinobacteria,4ED15@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158338_k127_144614_2	626887.J057_13416	6.334e-88	304.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,1SYDH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Dehydrogenase	adh	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158338_k127_144614_12	666686.B1NLA3E_07800	1.818e-20	103.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,1ZCMY@1386|Bacillus	91061|Bacilli	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158338_k127_14861_2	986075.CathTA2_2071	3.841e-20	94.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158338_k127_14861_1	1120973.AQXL01000133_gene1804	7.321e-38	145.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,279UH@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158338_k127_14861_0	936573.HMPREF1147_0896	1.584e-50	188.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes	1239|Firmicutes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158338_k127_152377_6	1121430.JMLG01000010_gene208	1.61e-58	215.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
SRR25158338_k127_152377_0	311424.DhcVS_1515	2.201e-158	511.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,34CW8@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
SRR25158338_k127_152377_5	926569.ANT_03090	1.487e-71	253.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158338_k127_152377_10	1043205.AFYF01000080_gene1824	6.253e-22	102.0	2DY8M@1|root,348MZ@2|Bacteria,2GTP4@201174|Actinobacteria,4FJK1@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_152377_4	479434.Sthe_2211	5.172e-86	294.0	COG0491@1|root,COG0491@2|Bacteria,2G846@200795|Chloroflexi,27YRW@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_152377_8	292459.STH513	1.091e-31	127.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158338_k127_152377_14	243164.DET0358	1.346e-06	56.0	2BQ9G@1|root,32J4A@2|Bacteria,2GAU8@200795|Chloroflexi,34DCZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_152377_3	311424.DhcVS_300	3.459e-120	405.0	28MN1@1|root,2ZAXN@2|Bacteria,2G6CU@200795|Chloroflexi,34D42@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_152377_12	243164.DET0353	1.593e-12	74.0	2A3TQ@1|root,30SBK@2|Bacteria,2G9W9@200795|Chloroflexi,34DJK@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_152377_1	311424.DhcVS_293	2.943e-146	477.0	COG3567@1|root,COG3567@2|Bacteria,2G7F0@200795|Chloroflexi,34DDN@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
SRR25158338_k127_152377_7	797209.ZOD2009_16563	2.834e-35	139.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158338_k127_152377_9	1236902.ANAS01000012_gene787	8.355e-29	119.0	COG3526@1|root,COG3526@2|Bacteria,2IRQ4@201174|Actinobacteria	201174|Actinobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158338_k127_152377_11	518766.Rmar_2288	1.518e-16	92.0	COG5615@1|root,COG5615@2|Bacteria,4P6NC@976|Bacteroidetes,1FK4A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	CopD
SRR25158338_k127_152377_2	653733.Selin_0177	1.372e-137	457.0	COG0104@1|root,COG0104@2|Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
SRR25158338_k127_152377_13	710687.KI912270_gene965	1.18e-08	62.0	COG3794@1|root,COG3794@2|Bacteria,2GS7W@201174|Actinobacteria,23AYF@1762|Mycobacteriaceae	201174|Actinobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158338_k127_1643557_2	591158.SSMG_04764	2.5e-36	149.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA1_1	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
SRR25158338_k127_1643557_1	1121377.KB906401_gene3435	2.797e-60	220.0	COG1708@1|root,COG1708@2|Bacteria,1WMKX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4111)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111
SRR25158338_k127_1643557_0	330214.NIDE3851	8.593e-175	556.0	COG0365@1|root,COG0365@2|Bacteria,3J0BJ@40117|Nitrospirae	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158338_k127_1650763_10	1303518.CCALI_02219	7.272e-66	229.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	hpnC	-	2.5.1.32,2.5.1.99,4.2.3.156	ko:K02291,ko:K21679	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158338_k127_1650763_29	1122179.KB890480_gene3150	6.44e-05	49.0	295U4@1|root,2ZT58@2|Bacteria,4PQ2P@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158338_k127_1650763_12	304371.MCP_2022	3.128e-59	219.0	COG1741@1|root,arCOG02935@2157|Archaea,2XTZ7@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158338_k127_1650763_5	1192759.AKIB01000045_gene833	1.712e-90	319.0	COG2141@1|root,COG2141@2|Bacteria,1R9CH@1224|Proteobacteria,2U46T@28211|Alphaproteobacteria,2K3UX@204457|Sphingomonadales	204457|Sphingomonadales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_1650763_0	931626.Awo_c12770	9.449e-186	619.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158338_k127_1650763_1	1382306.JNIM01000001_gene1617	8.212e-163	525.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158338_k127_1650763_14	309801.trd_0261	1.749e-56	212.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi,27XX4@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158338_k127_1650763_3	357808.RoseRS_3607	9.195e-109	368.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi,37729@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
SRR25158338_k127_1650763_26	935948.KE386495_gene1564	1.317e-14	81.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,24GZP@186801|Clostridia,42J3M@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158338_k127_1650763_28	1499683.CCFF01000014_gene3570	1.111e-07	59.0	COG1396@1|root,COG1396@2|Bacteria,1UV6W@1239|Firmicutes,2589A@186801|Clostridia,36MYK@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158338_k127_1650763_30	555500.I215_14306	0.0002032	50.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
SRR25158338_k127_1650763_16	926569.ANT_20670	1.597e-55	205.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158338_k127_1650763_18	635013.TherJR_2808	1.402e-46	183.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,25D46@186801|Clostridia,260VX@186807|Peptococcaceae	186801|Clostridia	U	PFAM type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158338_k127_1650763_2	401526.TcarDRAFT_1915	2.345e-152	494.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4H28E@909932|Negativicutes	909932|Negativicutes	U	PFAM Type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158338_k127_1650763_11	509191.AEDB02000063_gene453	2.45e-62	230.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,3WKMS@541000|Ruminococcaceae	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158338_k127_1650763_23	635013.TherJR_2811	2.542e-20	101.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,262WB@186807|Peptococcaceae	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158338_k127_1650763_25	941824.TCEL_00979	2.158e-17	87.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,36MCG@31979|Clostridiaceae	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158338_k127_1650763_21	1429046.RR21198_4115	4.619e-30	132.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria,4FWWC@85025|Nocardiaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158338_k127_1650763_20	316274.Haur_0806	1.537e-31	141.0	COG1807@1|root,COG1807@2|Bacteria,2G96F@200795|Chloroflexi,377WN@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1650763_22	266117.Rxyl_1154	5.774e-30	130.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4CQAS@84995|Rubrobacteria	84995|Rubrobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158338_k127_1650763_17	1382306.JNIM01000001_gene2904	5.754e-48	178.0	COG2320@1|root,COG2320@2|Bacteria,2G94B@200795|Chloroflexi	200795|Chloroflexi	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR25158338_k127_1650763_9	1439940.BAY1663_03239	4.066e-70	248.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phenazine biosynthesis protein PhzF	pab	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158338_k127_1650763_4	387631.Asulf_00176	1.901e-106	355.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158338_k127_1650763_13	589924.Ferp_1793	7.072e-59	214.0	COG2057@1|root,arCOG05316@2157|Archaea,2XW2C@28890|Euryarchaeota,246AI@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158338_k127_1650763_24	1487923.DP73_09300	5.047e-20	102.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,24GGW@186801|Clostridia,267CD@186807|Peptococcaceae	186801|Clostridia	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158338_k127_1650763_6	42256.RradSPS_0871	1.463e-81	279.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158338_k127_1650763_19	526225.Gobs_3403	1.638e-44	170.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4EUWC@85013|Frankiales	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158338_k127_1650763_8	1122611.KB903965_gene5000	2.993e-71	256.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EI5A@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_1650763_7	1828.JOKB01000052_gene3632	2.253e-75	263.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FX5G@85025|Nocardiaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158338_k127_1650763_15	1122917.KB899675_gene235	2.044e-56	206.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HDSC@91061|Bacilli,26RBB@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158338_k127_1650763_27	926550.CLDAP_22950	2.529e-13	74.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051,ko:K15598	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR25158338_k127_1667133_5	485913.Krac_8280	5.407e-49	185.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158338_k127_1667133_3	1449126.JQKL01000022_gene110	9.114e-120	401.0	COG1008@1|root,COG1008@2|Bacteria,1UHSH@1239|Firmicutes,24AAH@186801|Clostridia	186801|Clostridia	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158338_k127_1667133_0	552811.Dehly_0839	1.345e-179	583.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi,34D55@301297|Dehalococcoidia	301297|Dehalococcoidia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158338_k127_1667133_10	485913.Krac_8283	3.662e-24	107.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158338_k127_1667133_11	1121472.AQWN01000005_gene2478	1.108e-23	109.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,24NAC@186801|Clostridia,2626F@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158338_k127_1667133_4	255470.cbdbA879	4.495e-88	305.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi,34CTC@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158338_k127_1667133_2	552811.Dehly_0834	4.029e-140	461.0	COG0649@1|root,COG0649@2|Bacteria,2G5JF@200795|Chloroflexi,34D5Q@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158338_k127_1667133_9	552811.Dehly_0833	8.649e-30	125.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi,34DAA@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158338_k127_1667133_8	696281.Desru_1808	2.653e-31	130.0	COG0838@1|root,COG0838@2|Bacteria,1V6P3@1239|Firmicutes,24QYA@186801|Clostridia,2670N@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158338_k127_1667133_7	479434.Sthe_0539	4.26e-41	155.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,MaoC_dehydratas,OB_aCoA_assoc
SRR25158338_k127_1667133_1	1382304.JNIL01000001_gene1433	5.096e-156	508.0	COG0183@1|root,COG0183@2|Bacteria,1TRRD@1239|Firmicutes,4HC91@91061|Bacilli,279A4@186823|Alicyclobacillaceae	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158338_k127_1667133_6	933262.AXAM01000004_gene2383	6.905e-45	171.0	COG0613@1|root,COG0613@2|Bacteria,1NFVB@1224|Proteobacteria,43BBY@68525|delta/epsilon subdivisions,2X6R1@28221|Deltaproteobacteria,2MPIB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	APH,DUF2889,PHP_C
SRR25158338_k127_1680624_11	1121430.JMLG01000002_gene1071	5.354e-100	344.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,26184@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158338_k127_1680624_7	552811.Dehly_1121	1.75e-122	402.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,34CPV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158338_k127_1680624_20	1303518.CCALI_01951	5.046e-65	233.0	COG0177@1|root,COG0177@2|Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158338_k127_1680624_41	925409.KI911562_gene1382	6.534e-17	92.0	COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,1J006@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158338_k127_1680624_10	479434.Sthe_0838	1.477e-101	342.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158338_k127_1680624_40	395019.Bmul_5712	5.031e-19	94.0	COG1246@1|root,COG1246@2|Bacteria,1NX0C@1224|Proteobacteria,2W2MZ@28216|Betaproteobacteria,1KAR0@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158338_k127_1680624_15	266117.Rxyl_0345	7.713e-78	271.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158338_k127_1680624_23	386456.JQKN01000015_gene2945	4.49e-58	209.0	COG1704@1|root,arCOG04574@2157|Archaea,2XXB9@28890|Euryarchaeota,23PHV@183925|Methanobacteria	183925|Methanobacteria	S	PFAM LemA	-	-	-	-	-	-	-	-	-	-	-	-	LemA
SRR25158338_k127_1680624_18	1121430.JMLG01000009_gene427	1.481e-74	261.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,260S2@186807|Peptococcaceae	186801|Clostridia	GK	pfam rok	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
SRR25158338_k127_1680624_32	479434.Sthe_0073	2.297e-31	129.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158338_k127_1680624_2	292459.STH2897	1.224e-210	668.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158338_k127_1680624_0	671143.DAMO_0867	0.0	2023.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158338_k127_1680624_1	671143.DAMO_0866	4.738e-217	683.0	COG0493@1|root,COG0493@2|Bacteria,2NNUI@2323|unclassified Bacteria	2|Bacteria	E	Flavin containing amine oxidoreductase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
SRR25158338_k127_1680624_35	926550.CLDAP_15600	3.571e-23	104.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158338_k127_1680624_3	671143.DAMO_2616	1.987e-208	660.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158338_k127_1680624_8	526227.Mesil_2857	7.165e-114	393.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1WJR6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158338_k127_1680624_31	13690.CP98_00582	2.249e-33	131.0	COG0565@1|root,COG2827@1|root,COG0565@2|Bacteria,COG2827@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,2JZUG@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,SpoU_methylase
SRR25158338_k127_1680624_5	671143.DAMO_2615	1.635e-185	594.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158338_k127_1680624_29	58123.JOFJ01000013_gene4923	2.666e-36	141.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4EKJI@85012|Streptosporangiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158338_k127_1680624_9	1128421.JAGA01000002_gene1015	5.462e-113	375.0	COG0492@1|root,COG0492@2|Bacteria,2NP5X@2323|unclassified Bacteria	2|Bacteria	O	Pyridine nucleotide-disulphide oxidoreductase	yumC	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	iYO844.BSU32110	Pyr_redox_2,Pyr_redox_3
SRR25158338_k127_1680624_49	436229.JOEH01000049_gene6823	0.0001884	47.0	COG1309@1|root,COG1309@2|Bacteria,2IFIH@201174|Actinobacteria,2NIDB@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158338_k127_1680624_38	1220589.CD32_12000	4.489e-20	96.0	COG2318@1|root,COG2318@2|Bacteria,1V8HE@1239|Firmicutes,4HJ3X@91061|Bacilli	91061|Bacilli	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SRR25158338_k127_1680624_19	266117.Rxyl_1143	7.588e-71	250.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4CR7Z@84995|Rubrobacteria	84995|Rubrobacteria	P	ABC 3 transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158338_k127_1680624_17	479434.Sthe_2976	8.209e-76	263.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,27XH6@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158338_k127_1680624_25	1313172.YM304_20920	3.765e-47	185.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158338_k127_1680624_34	309801.trd_A0182	4.442e-29	122.0	COG0735@1|root,COG0735@2|Bacteria,2G74Y@200795|Chloroflexi,27YIH@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158338_k127_1680624_46	570268.ANBB01000037_gene2842	4.835e-06	58.0	COG5343@1|root,COG5343@2|Bacteria,2GUEC@201174|Actinobacteria	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158338_k127_1680624_28	1128421.JAGA01000003_gene3735	2.472e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,2NR8H@2323|unclassified Bacteria	2|Bacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158338_k127_1680624_22	479434.Sthe_3346	3.906e-63	231.0	COG0265@1|root,COG0265@2|Bacteria,2G8RK@200795|Chloroflexi,27Y6G@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158338_k127_1680624_21	266117.Rxyl_2532	1.297e-63	227.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria,4CTJ1@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
SRR25158338_k127_1680624_14	667014.Thein_1677	3.579e-83	284.0	COG0501@1|root,COG0501@2|Bacteria,2GH8X@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158338_k127_1680624_42	644966.Tmar_0494	1.313e-15	83.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
SRR25158338_k127_1680624_37	306281.AJLK01000110_gene2668	3.545e-21	99.0	COG0431@1|root,COG0431@2|Bacteria,1G651@1117|Cyanobacteria	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158338_k127_1680624_12	1118054.CAGW01000081_gene2720	7.79e-96	326.0	COG2141@1|root,COG2141@2|Bacteria,1TW8W@1239|Firmicutes,4HB95@91061|Bacilli,26QRC@186822|Paenibacillaceae	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	1.14.14.28,1.14.14.5	ko:K04091,ko:K20938	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158338_k127_1680624_27	1382306.JNIM01000001_gene1809	1.384e-36	144.0	COG1225@1|root,COG1225@2|Bacteria,2G6XD@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158338_k127_1680624_48	234267.Acid_4591	2.922e-05	56.0	COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158338_k127_1680624_36	251229.Chro_4900	6.032e-23	106.0	COG1853@1|root,COG1853@2|Bacteria,1G2RV@1117|Cyanobacteria,3VIX9@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158338_k127_1680624_6	935948.KE386494_gene372	1.498e-125	426.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,42FE6@68295|Thermoanaerobacterales	186801|Clostridia	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158338_k127_1680624_13	1379698.RBG1_1C00001G1217	9.372e-88	299.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2NP05@2323|unclassified Bacteria	2|Bacteria	H	Methylenetetrahydrofolate reductase	yitJ	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
SRR25158338_k127_1680624_26	309801.trd_0242	1.474e-38	149.0	COG1673@1|root,COG1673@2|Bacteria,2G9JU@200795|Chloroflexi,27Y95@189775|Thermomicrobia	189775|Thermomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR25158338_k127_1680624_33	525904.Tter_1413	7.981e-31	124.0	COG0316@1|root,COG0316@2|Bacteria,2NPZK@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the HesB IscA family	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158338_k127_1680624_47	665571.STHERM_c15100	9.761e-06	55.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,2J5NQ@203691|Spirochaetes	203691|Spirochaetes	C	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
SRR25158338_k127_1680624_43	240015.ACP_2278	1.898e-15	84.0	COG1011@1|root,COG1011@2|Bacteria,3Y4UV@57723|Acidobacteria,2JJJM@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158338_k127_1680624_4	255470.cbdbA1049	5.524e-195	623.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi,34CY9@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158338_k127_1680624_24	1128421.JAGA01000003_gene2726	2.136e-47	181.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158338_k127_1680624_45	479434.Sthe_1585	7.61e-13	73.0	2EKS3@1|root,33EFV@2|Bacteria,2GBBM@200795|Chloroflexi,27YP9@189775|Thermomicrobia	189775|Thermomicrobia	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158338_k127_1680624_16	479434.Sthe_1584	5.561e-76	262.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi,27YE2@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158338_k127_1680624_30	479434.Sthe_1583	6.089e-34	135.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,27XSC@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158338_k127_1723550_6	1121405.dsmv_0645	1.113e-64	227.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2MHR8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158338_k127_1723550_8	1122939.ATUD01000016_gene1827	2.179e-35	143.0	COG0662@1|root,COG0662@2|Bacteria,2GXUC@201174|Actinobacteria,4CT1G@84995|Rubrobacteria	84995|Rubrobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
SRR25158338_k127_1723550_7	1120973.AQXL01000131_gene2092	1.378e-61	229.0	COG0547@1|root,COG0547@2|Bacteria,1U213@1239|Firmicutes,4IBHZ@91061|Bacilli,279UN@186823|Alicyclobacillaceae	91061|Bacilli	E	Glycosyl transferase family, a/b domain	-	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158338_k127_1723550_5	264732.Moth_1840	2.021e-68	247.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,42G5U@68295|Thermoanaerobacterales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158338_k127_1723550_2	864051.BurJ1DRAFT_3857	3.865e-93	316.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,1KN3S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158338_k127_1723550_12	309801.trd_A0640	1.811e-13	79.0	COG3764@1|root,COG3764@2|Bacteria,2G77W@200795|Chloroflexi,27YHD@189775|Thermomicrobia	189775|Thermomicrobia	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158338_k127_1723550_11	1463926.JOCA01000002_gene6115	1.689e-16	88.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158338_k127_1723550_0	1382306.JNIM01000001_gene1396	5.756e-167	537.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158338_k127_1723550_9	1380347.JNII01000009_gene2274	3.156e-28	122.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158338_k127_1723550_3	243164.DET1375	1.087e-92	316.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,34D96@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158338_k127_1723550_10	498761.HM1_2103	6.938e-25	111.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158338_k127_1723550_4	526227.Mesil_3000	6.042e-73	250.0	COG2041@1|root,COG2041@2|Bacteria,1WJB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158338_k127_1723550_1	497964.CfE428DRAFT_2106	1.345e-136	445.0	COG1522@1|root,COG1522@2|Bacteria,46SDK@74201|Verrucomicrobia	74201|Verrucomicrobia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_173439_7	469371.Tbis_2888	6.352e-63	229.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4DX45@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158338_k127_173439_10	526227.Mesil_1129	1.123e-44	173.0	COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_173439_14	1041522.MCOL_V203515	1.367e-29	123.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158338_k127_173439_20	1206729.BAFZ01000034_gene4935	2.57e-06	50.0	COG0346@1|root,COG0346@2|Bacteria,2GN2E@201174|Actinobacteria,4FXQW@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158338_k127_173439_8	247634.GPB2148_2893	1.594e-62	220.0	COG2128@1|root,COG2128@2|Bacteria,1PC51@1224|Proteobacteria,1RS2U@1236|Gammaproteobacteria,1J74C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158338_k127_173439_4	402881.Plav_1540	6.516e-81	278.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,1JNV6@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158338_k127_173439_21	316055.RPE_2404	1.259e-05	51.0	COG2050@1|root,COG2050@2|Bacteria,1PP3J@1224|Proteobacteria,2U5E4@28211|Alphaproteobacteria,3JY0G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Thioesterase superfamily	MA20_28520	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158338_k127_173439_18	1095769.CAHF01000015_gene2791	1.502e-21	99.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VVH4@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158338_k127_173439_11	697281.Mahau_0958	5.262e-43	171.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,42F4N@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158338_k127_173439_5	246194.CHY_1736	4.313e-76	263.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149,5.3.3.18	ko:K07546,ko:K08299,ko:K15866	ko00360,ko00623,ko01100,ko01120,ko01220,map00360,map00623,map01100,map01120,map01220	M00418	R05599,R09837,R09839,R10675	RC00004,RC00326,RC01095,RC01435,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158338_k127_173439_2	471852.Tcur_3566	1.543e-96	340.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_173439_6	1128421.JAGA01000002_gene1502	1.875e-66	240.0	COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU05900	AIRS,AIRS_C
SRR25158338_k127_173439_12	349161.Dred_2888	2.876e-33	134.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158338_k127_173439_16	1521187.JPIM01000006_gene1732	9.245e-23	108.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi,375PU@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158338_k127_173439_9	1121468.AUBR01000008_gene2047	8.512e-59	207.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,42G92@68295|Thermoanaerobacterales	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158338_k127_173439_0	760568.Desku_1070	1.856e-218	705.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,260R2@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
SRR25158338_k127_173439_15	378806.STAUR_1855	2.512e-24	114.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2YVQW@29|Myxococcales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158338_k127_173439_1	1120985.AUMI01000015_gene1388	2.379e-105	353.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4H2P5@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158338_k127_173439_22	479434.Sthe_2114	0.000222	48.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi,27YHT@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_173439_23	1231185.BAMP01000117_gene1490	0.0002768	48.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158338_k127_173439_3	710111.FraQA3DRAFT_4730	1.335e-93	317.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158338_k127_173439_19	1499967.BAYZ01000090_gene4936	3.386e-10	74.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158338_k127_1744086_7	580340.Tlie_1652	2.74e-25	119.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
SRR25158338_k127_1744086_6	552811.Dehly_0643	8.088e-48	180.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi,34CVZ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158338_k127_1744086_4	552811.Dehly_1469	9.888e-93	322.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,34D7X@301297|Dehalococcoidia	301297|Dehalococcoidia	J	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158338_k127_1744086_9	1408311.JNJM01000004_gene3263	3.739e-08	59.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,2PSKQ@265975|Oribacterium	186801|Clostridia	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158338_k127_1744086_1	1303518.CCALI_02605	1.203e-106	376.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	6.3.2.2	ko:K01919,ko:K03072,ko:K03074,ko:K12257	ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070	M00118,M00335	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158338_k127_1744086_0	309801.trd_0508	1.46e-178	578.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158338_k127_1744086_3	1128421.JAGA01000002_gene1016	9.309e-99	332.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158338_k127_1744086_2	1382306.JNIM01000001_gene3511	2.177e-103	355.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158338_k127_1744086_8	743974.MBO_08297	3.67e-13	78.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,3NNC2@468|Moraxellaceae	1236|Gammaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158338_k127_1744086_5	311424.DhcVS_612	7.664e-56	199.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,34CSB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158338_k127_1783466_6	290398.Csal_3314	1.98e-44	173.0	COG0672@1|root,COG0672@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria,1XKJR@135619|Oceanospirillales	135619|Oceanospirillales	P	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
SRR25158338_k127_1783466_13	1353537.TP2_16660	1.414e-07	62.0	COG4454@1|root,COG4454@2|Bacteria,1N1PE@1224|Proteobacteria,2UCWF@28211|Alphaproteobacteria,2XPE3@285107|Thioclava	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,SoxE
SRR25158338_k127_1783466_7	247633.GP2143_04500	2.32e-44	168.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_1783466_5	1123487.KB892864_gene2136	1.279e-46	178.0	COG2334@1|root,COG2334@2|Bacteria,1R16N@1224|Proteobacteria,2W4AR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158338_k127_1783466_9	1118054.CAGW01000032_gene679	2.431e-39	157.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,26RI9@186822|Paenibacillaceae	91061|Bacilli	M	Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	vanYB	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158338_k127_1783466_4	675635.Psed_4123	1.369e-58	209.0	COG0778@1|root,COG0778@2|Bacteria,2I6AB@201174|Actinobacteria,4E92W@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158338_k127_1783466_10	1288083.AUKR01000009_gene2019	7.996e-37	149.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158338_k127_1783466_11	883078.HMPREF9695_00768	2.969e-26	121.0	COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,2UAA7@28211|Alphaproteobacteria,3K03I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158338_k127_1783466_3	1382306.JNIM01000001_gene1897	3.851e-98	329.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158338_k127_1783466_12	479434.Sthe_3097	3.855e-19	97.0	2BQKI@1|root,32JGJ@2|Bacteria,2G9SN@200795|Chloroflexi,27YIJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158338_k127_1783466_1	1121346.KB899815_gene1901	8.979e-162	538.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158338_k127_1783466_2	1304880.JAGB01000002_gene2025	8.71e-145	473.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158338_k127_1783466_8	1336234.JAGN01000009_gene1314	1.131e-43	167.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,27FRV@186828|Carnobacteriaceae	91061|Bacilli	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158338_k127_1783466_0	555079.Toce_0353	4.059e-206	655.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,42EXT@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158338_k127_1787374_2	497964.CfE428DRAFT_2876	2.225e-64	223.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158338_k127_1787374_0	671143.DAMO_1610	4.427e-139	452.0	COG3635@1|root,COG3635@2|Bacteria,2NP0Y@2323|unclassified Bacteria	2|Bacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158338_k127_1787374_1	311424.DhcVS_649	5.482e-68	241.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi,34CU5@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158338_k127_1798494_4	1206732.BAGD01000281_gene6605	1.803e-08	58.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,4G2MJ@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_1798494_1	2074.JNYD01000001_gene5857	6.979e-88	304.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4E60J@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
SRR25158338_k127_1798494_0	247634.GPB2148_1760	3.232e-135	440.0	2DB8I@1|root,2Z7RY@2|Bacteria,1MY4M@1224|Proteobacteria,1SPR1@1236|Gammaproteobacteria,1JAR1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1798494_3	319003.Bra1253DRAFT_01281	9.916e-20	98.0	COG1309@1|root,COG1309@2|Bacteria,1MW6I@1224|Proteobacteria,2UBXJ@28211|Alphaproteobacteria,3JVS9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158338_k127_1798494_2	311424.DhcVS_700	5.166e-40	154.0	COG1131@1|root,COG1131@2|Bacteria,2G5Z4@200795|Chloroflexi,34CPN@301297|Dehalococcoidia	301297|Dehalococcoidia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158338_k127_1800878_8	1321814.HMPREF9089_00109	8.439e-59	210.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,25V1T@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158338_k127_1800878_9	742817.HMPREF9449_01692	5.572e-40	153.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,22XMM@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158338_k127_1800878_10	1120985.AUMI01000011_gene218	1.371e-23	110.0	COG1917@1|root,COG1917@2|Bacteria,1V7FN@1239|Firmicutes,4H6C3@909932|Negativicutes	909932|Negativicutes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158338_k127_1800878_0	552811.Dehly_0658	9.186e-167	535.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,34CSN@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158338_k127_1800878_2	479434.Sthe_1292	7.663e-105	348.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158338_k127_1800878_12	452652.KSE_37680	4.61e-16	84.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria,2M57W@2063|Kitasatospora	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158338_k127_1800878_14	1121938.AUDY01000013_gene3327	2.914e-07	59.0	COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,3NEXS@45667|Halobacillus	91061|Bacilli	S	Protein of unknown function (DUF1569)	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158338_k127_1800878_11	1123252.ATZF01000017_gene1723	5.335e-22	99.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,27CAM@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphoribosylformylglycinamidine (FGAM) synthase	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158338_k127_1800878_13	146922.JOFU01000052_gene2282	1.178e-10	68.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158338_k127_1800878_7	78245.Xaut_2293	9.905e-61	223.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,3EYI1@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	imidazoleglycerol-phosphate dehydratase activity	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9,3.1.3.15,4.2.1.19	ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03013,R03243,R03457	RC00006,RC00017,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	IGPD
SRR25158338_k127_1800878_4	383372.Rcas_0200	2.045e-102	346.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi,37543@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158338_k127_1800878_1	479434.Sthe_1676	3.268e-132	435.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi,27XKM@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158338_k127_1800878_15	1396.DJ87_2669	0.0003764	51.0	2DBCC@1|root,2Z8CP@2|Bacteria,1TSVG@1239|Firmicutes,4HFE3@91061|Bacilli,1ZG9P@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
SRR25158338_k127_1800878_3	243164.DET0845	1.959e-103	352.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi,34CWY@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
SRR25158338_k127_1800878_6	255470.cbdbA829	5.707e-76	271.0	COG0124@1|root,COG0124@2|Bacteria,2G962@200795|Chloroflexi,34CX8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
SRR25158338_k127_1800878_5	309801.trd_1267	1.881e-95	328.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158338_k127_1809566_3	1128421.JAGA01000002_gene196	1.447e-28	119.0	COG2890@1|root,COG2890@2|Bacteria,2NPDN@2323|unclassified Bacteria	2|Bacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158338_k127_1809566_4	338966.Ppro_2516	1.456e-11	76.0	COG0392@1|root,COG0392@2|Bacteria,1N7DR@1224|Proteobacteria,42N4R@68525|delta/epsilon subdivisions,2WS5Z@28221|Deltaproteobacteria,43TTU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158338_k127_1809566_2	1429916.X566_16655	3.049e-90	316.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2015, Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRR25158338_k127_1809566_1	391625.PPSIR1_25986	2.925e-90	316.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169,iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
SRR25158338_k127_1809566_0	1449976.KALB_7726	3.452e-105	354.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DZQQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
SRR25158338_k127_1842727_2	309807.SRU_0365	1.426e-49	191.0	COG2271@1|root,COG2271@2|Bacteria,4PEWT@976|Bacteroidetes,1FJRP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_1842727_1	525904.Tter_1681	2.649e-55	208.0	COG2843@1|root,COG3103@1|root,COG2843@2|Bacteria,COG4991@2|Bacteria,2NPJI@2323|unclassified Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	2.7.11.1	ko:K07282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PGA_cap,SH3_3,SH3_4
SRR25158338_k127_1842727_0	13690.CP98_00468	1.14e-96	329.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_1842727_3	926560.KE387027_gene824	2.944e-11	69.0	COG2318@1|root,COG2318@2|Bacteria,1WNBD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158338_k127_184822_2	196162.Noca_4966	6.947e-184	600.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158338_k127_184822_14	867903.ThesuDRAFT_01987	4.148e-33	144.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158338_k127_184822_5	469383.Cwoe_3624	7.257e-130	445.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158338_k127_184822_10	767817.Desgi_3217	1.515e-83	286.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,25EG6@186801|Clostridia,265GT@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_184822_13	309800.C498_00545	2.482e-43	171.0	COG1028@1|root,arCOG01259@2157|Archaea,2XUNT@28890|Euryarchaeota,23U46@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158338_k127_184822_4	224325.AF_2100	2.906e-141	469.0	COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,245VB@183980|Archaeoglobi	28890|Euryarchaeota	E	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158338_k127_184822_6	1298867.AUES01000031_gene2040	2.358e-120	398.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2U0A2@28211|Alphaproteobacteria,3JUZV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_184822_16	319795.Dgeo_0121	2.231e-18	97.0	COG0208@1|root,COG0208@2|Bacteria,1WM54@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	fatty acid desaturase	staD	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
SRR25158338_k127_184822_1	479433.Caci_0163	1.175e-190	611.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158338_k127_184822_3	1223543.GP2_032_00280	2.189e-179	585.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4GARZ@85026|Gordoniaceae	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.4.1.3,6.4.1.4	ko:K01965,ko:K01968	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158338_k127_184822_9	1122611.KB903941_gene2261	1.394e-83	286.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,4EIT6@85012|Streptosporangiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
SRR25158338_k127_184822_11	928724.SacglDRAFT_01399	2.223e-78	278.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4DZN3@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158338_k127_184822_0	882083.SacmaDRAFT_5376	3.603e-232	733.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4DX6T@85010|Pseudonocardiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158338_k127_184822_7	1133849.O3I_026255	4.431e-114	397.0	COG0577@1|root,COG0577@2|Bacteria,2HHSC@201174|Actinobacteria,4FZWK@85025|Nocardiaceae	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158338_k127_184822_8	565033.GACE_0018	8.612e-88	302.0	COG1136@1|root,arCOG00922@2157|Archaea,2XXQB@28890|Euryarchaeota,246SI@183980|Archaeoglobi	183980|Archaeoglobi	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158338_k127_184822_15	1245469.S58_61200	4.199e-19	95.0	COG1309@1|root,COG1309@2|Bacteria,1MW6I@1224|Proteobacteria,2UBXJ@28211|Alphaproteobacteria,3JVS9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158338_k127_184822_12	66429.JOFL01000006_gene2144	1.792e-54	197.0	COG1233@1|root,COG1233@2|Bacteria,2GP0A@201174|Actinobacteria	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158338_k127_1852001_1	1242864.D187_006755	4.148e-128	418.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158338_k127_1852001_14	1168059.KB899087_gene143	1.513e-30	131.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,3EZ7T@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158338_k127_1852001_15	326427.Cagg_2298	1.367e-29	127.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi,375KS@32061|Chloroflexia	32061|Chloroflexia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158338_k127_1852001_9	292459.STH794	4.7e-58	217.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158338_k127_1852001_8	555088.DealDRAFT_1141	8.759e-59	218.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1852001_0	644966.Tmar_0757	1.892e-171	547.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158338_k127_1852001_18	1123288.SOV_2c05500	9.851e-19	94.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4H57T@909932|Negativicutes	909932|Negativicutes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158338_k127_1852001_13	552811.Dehly_0754	7.775e-46	169.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,34DBK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158338_k127_1852001_17	552811.Dehly_0753	1.118e-21	98.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi,34DBB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158338_k127_1852001_20	1123239.KB898630_gene2525	1.827e-07	63.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes	1239|Firmicutes	M	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,Trigger_C
SRR25158338_k127_1852001_3	1449126.JQKL01000032_gene1234	5.312e-116	387.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,26822@186813|unclassified Clostridiales	186801|Clostridia	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158338_k127_1852001_2	43759.JNWK01000034_gene3023	5.263e-127	415.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_1852001_16	1394178.AWOO02000055_gene858	9.67e-28	119.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria,4EQUU@85012|Streptosporangiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158338_k127_1852001_6	264732.Moth_0408	7.11e-70	241.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,42EVI@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM GTP cyclohydrolase I Nitrile oxidoreductase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158338_k127_1852001_19	1205680.CAKO01000029_gene5260	8.729e-17	86.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
SRR25158338_k127_1852001_5	485913.Krac_7849	2.98e-103	349.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158338_k127_1852001_12	1125863.JAFN01000001_gene2314	8.82e-50	191.0	COG2120@1|root,COG2120@2|Bacteria,1MUTM@1224|Proteobacteria,42Q20@68525|delta/epsilon subdivisions,2WP8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158338_k127_1852001_10	1184607.AUCHE_17_00200	1.072e-55	206.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4F6E4@85018|Dermatophilaceae	201174|Actinobacteria	O	Cytochrome C assembly protein	resC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158338_k127_1852001_7	1128421.JAGA01000002_gene690	2.947e-64	223.0	COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria	2|Bacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158338_k127_1852001_11	479434.Sthe_1032	7.188e-55	199.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158338_k127_1852001_4	926569.ANT_10010	1.89e-110	363.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158338_k127_190471_7	402881.Plav_1800	1.313e-40	153.0	COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,2U8BE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158338_k127_190471_6	1267535.KB906767_gene2666	1.153e-48	179.0	COG0698@1|root,COG0698@2|Bacteria,3Y50S@57723|Acidobacteria,2JJEK@204432|Acidobacteriia	204432|Acidobacteriia	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158338_k127_190471_3	204669.Acid345_2810	2.365e-122	405.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158338_k127_190471_2	479434.Sthe_2434	2.291e-149	490.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi,27XXA@189775|Thermomicrobia	189775|Thermomicrobia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
SRR25158338_k127_190471_4	765420.OSCT_1272	9.399e-114	377.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,375RD@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158338_k127_190471_0	357808.RoseRS_2562	1.165e-193	619.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158338_k127_190471_8	324602.Caur_0502	1.948e-30	135.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158338_k127_190471_1	1173028.ANKO01000058_gene3036	3.611e-171	568.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg
SRR25158338_k127_190471_9	386456.JQKN01000002_gene2439	1.322e-25	117.0	COG0637@1|root,arCOG02293@2157|Archaea	2157|Archaea	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158338_k127_190471_5	386456.JQKN01000002_gene2438	3.315e-100	340.0	COG3919@1|root,arCOG06897@2157|Archaea	2157|Archaea	S	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1906440_4	258594.RPA3562	5.208e-86	297.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria,3K275@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158338_k127_1906440_6	457425.XNR_3215	1.118e-21	98.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158338_k127_1906440_5	401526.TcarDRAFT_0025	3.819e-32	130.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,4H4CB@909932|Negativicutes	909932|Negativicutes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158338_k127_1906440_8	357808.RoseRS_1855	0.000158	44.0	COG1528@1|root,COG1528@2|Bacteria,2G8JG@200795|Chloroflexi,37728@32061|Chloroflexia	32061|Chloroflexia	C	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158338_k127_1906440_2	1449049.JONW01000012_gene6	1.511e-118	392.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2U14P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158338_k127_1906440_3	243164.DET0737	3.208e-114	381.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,34D24@301297|Dehalococcoidia	301297|Dehalococcoidia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158338_k127_1906440_7	391616.OA238_c11750	3.987e-05	55.0	COG3794@1|root,COG3794@2|Bacteria,1NM0N@1224|Proteobacteria,2UKBR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158338_k127_1906440_1	1521187.JPIM01000008_gene2114	3.488e-148	488.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi,37536@32061|Chloroflexia	32061|Chloroflexia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158338_k127_1906440_0	479434.Sthe_0669	2.054e-193	626.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158338_k127_1911304_22	292459.STH1444	3.693e-26	111.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_1911304_20	42256.RradSPS_0329	3.55e-33	135.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	aacA	-	2.3.1.57,2.3.1.82	ko:K00657,ko:K00663,ko:K19278,ko:K19301	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_3,Acetyltransf_8
SRR25158338_k127_1911304_9	552811.Dehly_0683	1.098e-74	269.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi,34D4G@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
SRR25158338_k127_1911304_6	311424.DhcVS_617	2.067e-83	282.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi,34D07@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158338_k127_1911304_2	1121335.Clst_2384	6.249e-165	530.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158338_k127_1911304_10	479434.Sthe_1208	1.4e-72	262.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158338_k127_1911304_15	926550.CLDAP_14750	3.702e-54	203.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158338_k127_1911304_17	1121472.AQWN01000003_gene1525	6.114e-43	164.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,26230@186807|Peptococcaceae	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158338_k127_1911304_11	1379698.RBG1_1C00001G0454	4.737e-69	243.0	2CEY7@1|root,2Z8CG@2|Bacteria,2NR2B@2323|unclassified Bacteria	2|Bacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1911304_0	351607.Acel_1865	3.489e-281	874.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158338_k127_1911304_4	671143.DAMO_1992	1.768e-118	384.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRR25158338_k127_1911304_8	479434.Sthe_0899	7.443e-77	269.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,27XQ4@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158338_k127_1911304_23	360107.CHAB381_0223	3.804e-25	105.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2YQ19@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158338_k127_1911304_21	762983.HMPREF9444_00039	1.438e-29	120.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1Y5U9@135624|Aeromonadales	135624|Aeromonadales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158338_k127_1911304_24	869210.Marky_0263	1.161e-24	114.0	COG0261@1|root,COG0261@2|Bacteria,1WKB6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158338_k127_1911304_1	1382356.JQMP01000003_gene2325	8.587e-237	748.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,27XT6@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SRR25158338_k127_1911304_28	89187.ISM_07350	5.894e-11	65.0	COG1942@1|root,COG1942@2|Bacteria,1NG98@1224|Proteobacteria,2UK0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	4-oxalocrotonate tautomerase	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase
SRR25158338_k127_1911304_16	927704.SELR_20600	9.667e-52	194.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158338_k127_1911304_5	1299327.I546_1272	9.113e-109	361.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,2360H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotriesterase	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
SRR25158338_k127_1911304_27	1160721.RBI_I01111	2.921e-15	81.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WKWI@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158338_k127_1911304_14	1408419.JHYG01000003_gene262	5.67e-57	211.0	COG0535@1|root,COG0535@2|Bacteria,1Q8U2@1224|Proteobacteria,2UYJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158338_k127_1911304_18	35754.JNYJ01000043_gene4438	9.557e-40	159.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4DIVE@85008|Micromonosporales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158338_k127_1911304_19	1048339.KB913029_gene4254	1.439e-39	159.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158338_k127_1911304_30	709032.Sulku_2342	4.567e-07	64.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158338_k127_1911304_25	479434.Sthe_1281	1.179e-19	94.0	COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,27YPR@189775|Thermomicrobia	189775|Thermomicrobia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158338_k127_1911304_29	479434.Sthe_1281	3.49e-10	65.0	COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,27YPR@189775|Thermomicrobia	189775|Thermomicrobia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158338_k127_1911304_13	309801.trd_0162	3.706e-58	209.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,27Y62@189775|Thermomicrobia	189775|Thermomicrobia	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
SRR25158338_k127_1911304_26	485913.Krac_3478	3.954e-19	95.0	2DU4Y@1|root,33NY5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1911304_7	1380390.JIAT01000012_gene3177	1.794e-77	277.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,4CT1M@84995|Rubrobacteria	84995|Rubrobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
SRR25158338_k127_1911304_12	243164.DET1381	7.033e-69	253.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,34CT3@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HisKA_7TM
SRR25158338_k127_1911304_3	479434.Sthe_1621	1.192e-152	490.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia	189775|Thermomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
SRR25158338_k127_1913156_1	589865.DaAHT2_0738	1.549e-107	362.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MHYA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
SRR25158338_k127_1913156_2	204669.Acid345_0349	3.789e-53	196.0	COG1075@1|root,COG1075@2|Bacteria,3Y77G@57723|Acidobacteria	57723|Acidobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1913156_0	251229.Chro_4538	3.22e-129	432.0	COG0028@1|root,COG0028@2|Bacteria,1G2XN@1117|Cyanobacteria	1117|Cyanobacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158338_k127_1930967_15	585425.KR52_05565	1.567e-10	70.0	COG3173@1|root,COG3173@2|Bacteria,1GHG3@1117|Cyanobacteria,1GYKS@1129|Synechococcus	1117|Cyanobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158338_k127_1930967_3	439235.Dalk_3873	3.741e-125	412.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42QX5@68525|delta/epsilon subdivisions,2WMXW@28221|Deltaproteobacteria,2MJHC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158338_k127_1930967_2	345341.KUTG_08194	1.088e-131	440.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158338_k127_1930967_1	1120950.KB892773_gene1095	2.669e-144	485.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DPXV@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158338_k127_1930967_7	479434.Sthe_0209	1.946e-54	196.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158338_k127_1930967_17	1122927.KB895412_gene1052	2.928e-09	69.0	COG2211@1|root,COG2211@2|Bacteria,1UZ5N@1239|Firmicutes,4HDUD@91061|Bacilli,26QM5@186822|Paenibacillaceae	91061|Bacilli	G	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_1930967_9	1254432.SCE1572_44745	7.167e-50	181.0	COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
SRR25158338_k127_1930967_5	1449126.JQKL01000002_gene1596	7.748e-83	291.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,2687I@186813|unclassified Clostridiales	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase N-terminal domain	cat	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158338_k127_1930967_0	1144275.COCOR_06731	2.198e-165	533.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158338_k127_1930967_14	796942.HMPREF9623_01591	1.285e-13	77.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158338_k127_1930967_4	926550.CLDAP_16150	2.933e-108	367.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,DUF3179
SRR25158338_k127_1930967_13	1121448.DGI_2325	1.429e-30	135.0	COG0535@1|root,COG0535@2|Bacteria,1NVXA@1224|Proteobacteria,42NYH@68525|delta/epsilon subdivisions,2WY0S@28221|Deltaproteobacteria,2M9B8@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158338_k127_1930967_8	926550.CLDAP_35570	6.737e-54	199.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158338_k127_1930967_16	926550.CLDAP_21350	1.22e-09	63.0	299CS@1|root,2ZWFP@2|Bacteria,2G9JC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1930967_11	525904.Tter_1733	1.07e-41	163.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158338_k127_1930967_6	266117.Rxyl_1821	7.074e-70	247.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CQ2F@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158338_k127_1930967_10	156889.Mmc1_1813	4.938e-46	179.0	COG0784@1|root,COG2203@1|root,COG3437@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2U2AJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	DUF3369,HD,HD_5,Response_reg
SRR25158338_k127_1930967_12	1313172.YM304_38800	9.139e-31	128.0	COG0344@1|root,COG0344@2|Bacteria,2IFX1@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158338_k127_1940534_13	765910.MARPU_07675	1.941e-11	66.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1WXR9@135613|Chromatiales	135613|Chromatiales	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_1940534_15	89187.ISM_12335	0.0009234	48.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,46NVF@74030|Roseovarius	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_1940534_12	886293.Sinac_4756	1.54e-12	76.0	COG0515@1|root,COG0515@2|Bacteria,2IYF2@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase
SRR25158338_k127_1940534_0	1121472.AQWN01000004_gene717	6.903e-133	434.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,24ZA8@186801|Clostridia	186801|Clostridia	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_1940534_10	479434.Sthe_0413	2.501e-18	99.0	COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_1940534_1	1382356.JQMP01000003_gene1443	1.304e-127	434.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi,27Y1G@189775|Thermomicrobia	189775|Thermomicrobia	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158338_k127_1940534_8	561180.BIFGAL_03349	3.934e-23	107.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4D10G@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158338_k127_1940534_2	1382306.JNIM01000001_gene1299	1.887e-98	345.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158338_k127_1940534_4	1121405.dsmv_3719	4.608e-68	256.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2MI64@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158338_k127_1940534_14	1408428.JNJP01000122_gene1695	8.514e-07	52.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2M7VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158338_k127_1940534_3	243164.DET0962	8.682e-96	328.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi,34D8Z@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158338_k127_1940534_7	383372.Rcas_4453	4.364e-32	133.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,375NU@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158338_k127_1940534_9	552811.Dehly_0984	1.463e-22	100.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi,34DEY@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158338_k127_1940534_11	309801.trd_0352	2.427e-14	82.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi,27XWE@189775|Thermomicrobia	189775|Thermomicrobia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158338_k127_1940534_6	479434.Sthe_3353	8.322e-33	142.0	COG1295@1|root,COG1295@2|Bacteria,2GARF@200795|Chloroflexi,27Z8N@189775|Thermomicrobia	189775|Thermomicrobia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158338_k127_1940534_5	243164.DET1038	3.955e-65	231.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,34CUX@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158338_k127_1976543_2	446462.Amir_6415	8.555e-31	126.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria,4E0A9@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase dimerisation domain	amiB1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158338_k127_1976543_1	1521187.JPIM01000068_gene743	5.565e-57	203.0	COG0503@1|root,COG0503@2|Bacteria,2G8K9@200795|Chloroflexi,375M9@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158338_k127_1976543_0	1267535.KB906767_gene4340	1.971e-107	361.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158338_k127_1986380_29	622637.KE124774_gene929	4.248e-30	122.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,36XGA@31993|Methylocystaceae	28211|Alphaproteobacteria	I	YgbB family	ispDF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158338_k127_1986380_20	1382356.JQMP01000004_gene629	3.347e-51	188.0	COG0245@1|root,COG0245@2|Bacteria,2G6RA@200795|Chloroflexi,27YBC@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158338_k127_1986380_0	525904.Tter_1827	5.411e-212	663.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158338_k127_1986380_33	525904.Tter_1826	9.246e-15	74.0	COG0267@1|root,COG0267@2|Bacteria,2NQ3R@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158338_k127_1986380_35	243164.DET0995	3.441e-10	64.0	COG0690@1|root,COG0690@2|Bacteria,2G9VX@200795|Chloroflexi,34DH3@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158338_k127_1986380_12	311424.DhcVS_866	1.027e-67	237.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,34CRP@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158338_k127_1986380_15	246194.CHY_2323	7.435e-61	213.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,42G61@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158338_k127_1986380_8	644966.Tmar_2306	4.268e-80	274.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WCDB@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158338_k127_1986380_27	383372.Rcas_4318	2.125e-31	132.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi,375RJ@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158338_k127_1986380_24	479434.Sthe_1604	1.4e-36	143.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi,27YF7@189775|Thermomicrobia	189775|Thermomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158338_k127_1986380_37	926550.CLDAP_14770	0.0001282	51.0	COG1388@1|root,COG1388@2|Bacteria,2G95J@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_C39_2
SRR25158338_k127_1986380_11	1229780.BN381_330062	4.846e-72	257.0	COG4690@1|root,COG4690@2|Bacteria	2|Bacteria	E	dipeptidase activity	-	-	-	ko:K14358	-	-	-	-	ko00000,ko01002	-	-	-	AAT,Peptidase_C69
SRR25158338_k127_1986380_10	479434.Sthe_0347	3.321e-72	250.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,27XF2@189775|Thermomicrobia	189775|Thermomicrobia	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158338_k127_1986380_25	349161.Dred_3056	9.173e-36	147.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,2673P@186807|Peptococcaceae	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158338_k127_1986380_13	243231.GSU0387	3.107e-62	226.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,43UBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158338_k127_1986380_31	243164.DET1457	1.275e-26	113.0	2EQ8R@1|root,33HV0@2|Bacteria,2G91J@200795|Chloroflexi,34DHP@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1986380_28	357808.RoseRS_4493	3.481e-30	138.0	COG0741@1|root,COG0741@2|Bacteria	357808.RoseRS_4493|-	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1986380_19	1304866.K413DRAFT_0290	4.314e-52	195.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,36W8R@31979|Clostridiaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR25158338_k127_1986380_9	316274.Haur_3133	1.483e-76	264.0	COG1134@1|root,COG1134@2|Bacteria,2G6D9@200795|Chloroflexi,37500@32061|Chloroflexia	32061|Chloroflexia	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158338_k127_1986380_4	1037409.BJ6T_04140	8.527e-106	361.0	COG2263@1|root,COG2263@2|Bacteria,1R26A@1224|Proteobacteria	1224|Proteobacteria	J	DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_1986380_36	493475.GARC_1709	2.083e-05	57.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria	1224|Proteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
SRR25158338_k127_1986380_30	398767.Glov_2347	1.503e-27	130.0	COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1PFT2@1224|Proteobacteria,439ZB@68525|delta/epsilon subdivisions,2XA08@28221|Deltaproteobacteria,43VGB@69541|Desulfuromonadales	2|Bacteria	M	Glycosyl transferase, family 2	yfnF	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Nucleotid_trans
SRR25158338_k127_1986380_17	1294142.CINTURNW_4063	4.784e-57	223.0	COG1216@1|root,COG1216@2|Bacteria,1V06G@1239|Firmicutes,247WU@186801|Clostridia,36GAS@31979|Clostridiaceae	186801|Clostridia	H	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
SRR25158338_k127_1986380_3	1146883.BLASA_4159	1.167e-112	387.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23,Methyltransf_25,Methyltransf_32
SRR25158338_k127_1986380_18	1041930.Mtc_0198	5.744e-56	207.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
SRR25158338_k127_1986380_2	1120950.KB892756_gene6678	1.825e-115	383.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4DNRQ@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158338_k127_1986380_1	112098.XP_008604901.1	2.611e-119	392.0	COG1088@1|root,KOG0747@2759|Eukaryota	2759|Eukaryota	M	dTDP-glucose 4,6-dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2,GDP_Man_Dehyd,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158338_k127_1986380_34	304371.MCP_2716	2.847e-11	69.0	COG1898@1|root,arCOG04188@2157|Archaea,2XWJQ@28890|Euryarchaeota,2NASX@224756|Methanomicrobia	224756|Methanomicrobia	M	WxcM-like, C-terminal	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158338_k127_1986380_14	1128421.JAGA01000002_gene1831	2.289e-61	222.0	COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	1.1.1.133,5.1.3.13,5.1.3.26	ko:K00067,ko:K01790,ko:K19997	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_1929,iEcHS_1320.EcHS_A2180,iJN678.rfbD	RmlD_sub_bind
SRR25158338_k127_1986380_22	1521187.JPIM01000231_gene2779	1.286e-44	173.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,374ZJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158338_k127_1986380_16	765910.MARPU_10165	1.424e-57	216.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RY0F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158338_k127_1986380_21	679201.HMPREF9334_02088	1.677e-45	175.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4H2TE@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRR25158338_k127_1986380_32	1120950.KB892743_gene3107	1.151e-22	112.0	COG2244@1|root,COG2244@2|Bacteria,2HRUY@201174|Actinobacteria,4DVHG@85009|Propionibacteriales	201174|Actinobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158338_k127_1986380_23	552811.Dehly_1373	7.484e-41	162.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi,34CXC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
SRR25158338_k127_1986380_7	266117.Rxyl_2907	2.393e-82	285.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4CRIV@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158338_k127_1986380_26	1449347.JQLN01000005_gene4592	4.169e-33	136.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,2M3DD@2063|Kitasatospora	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158338_k127_1986380_5	266117.Rxyl_1173	5.711e-94	331.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158338_k127_1986380_6	42256.RradSPS_1164	3.302e-90	304.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158338_k127_1987610_0	96561.Dole_0194	3.998e-180	588.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158338_k127_1987610_1	1121422.AUMW01000014_gene1319	1.068e-132	434.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_1987610_2	1348657.M622_04425	2.138e-43	169.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158338_k127_2000190_1	644966.Tmar_1485	1.579e-112	371.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,3WDC4@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158338_k127_2000190_0	867903.ThesuDRAFT_01362	9.338e-114	373.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia	186801|Clostridia	C	oxidoreductase beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158338_k127_2000190_2	644966.Tmar_1487	4.02e-21	98.0	COG5502@1|root,COG5502@2|Bacteria	2|Bacteria	V	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158338_k127_2076660_3	1382306.JNIM01000001_gene1165	8.27e-25	105.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158338_k127_2076660_0	255470.cbdbA482	2.766e-107	356.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi,34D1X@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtaP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158338_k127_2076660_4	68260.JOAY01000024_gene1073	2.92e-24	114.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158338_k127_2076660_2	365528.KB891103_gene4126	5.064e-49	183.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria,4ESZP@85013|Frankiales	201174|Actinobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158338_k127_2076660_1	1123060.JONP01000004_gene733	1.944e-57	209.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria,2TRJZ@28211|Alphaproteobacteria,2JWJI@204441|Rhodospirillales	204441|Rhodospirillales	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SRR25158338_k127_2119477_21	335543.Sfum_2007	4.279e-29	117.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MRIT@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_2119477_8	269799.Gmet_3382	1.939e-93	323.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,43BSP@68525|delta/epsilon subdivisions,2X7EK@28221|Deltaproteobacteria,43W43@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158338_k127_2119477_17	1121324.CLIT_2c03230	5.085e-36	147.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SRR25158338_k127_2119477_24	110319.CF8_4099	1.942e-19	92.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158338_k127_2119477_4	485913.Krac_4166	1.466e-134	434.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158338_k127_2119477_6	247639.MGP2080_01185	5.327e-97	324.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RR3Z@1236|Gammaproteobacteria,1J50U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	caiD	GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006575,GO:0006577,GO:0006579,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0008809,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009437,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0034641,GO:0042178,GO:0042219,GO:0042221,GO:0042413,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097164,GO:0098754,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	4.2.1.149,4.2.1.17,5.3.3.18	ko:K01692,ko:K08299,ko:K15866	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R09837,R09839,R10675	RC00004,RC00326,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1945,iEC042_1314.EC042_0038,iECABU_c1320.ECABU_c00410,iECB_1328.ECB_00040,iECD_1391.ECD_00040,iECO103_1326.ECO103_0038,iECP_1309.ECP_0036,iETEC_1333.ETEC_0036,iNRG857_1313.NRG857_00190,iUMN146_1321.UM146_22960,ic_1306.c0045	ECH_1
SRR25158338_k127_2119477_23	1292034.OR37_02270	6.849e-21	106.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U0S6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158338_k127_2119477_0	1297865.APJD01000003_gene6058	1.018e-297	930.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,3JVJZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158338_k127_2119477_18	397278.JOJN01000010_gene2219	7.516e-33	136.0	COG1309@1|root,COG1309@2|Bacteria,2IEU9@201174|Actinobacteria,4DW3K@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158338_k127_2119477_11	479434.Sthe_2045	1.8e-61	227.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	imuB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS
SRR25158338_k127_2119477_27	929712.KI912613_gene3056	5.434e-07	60.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2119477_2	1449976.KALB_8083	1.737e-225	737.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DYKC@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158338_k127_2119477_14	575540.Isop_3288	6.379e-47	181.0	COG0697@1|root,COG0697@2|Bacteria,2IZW8@203682|Planctomycetes	203682|Planctomycetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158338_k127_2119477_16	644966.Tmar_1600	1.8e-42	165.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,24IDC@186801|Clostridia	186801|Clostridia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158338_k127_2119477_19	1292020.H483_0102515	9.162e-33	133.0	COG3945@1|root,COG3945@2|Bacteria,2I4J6@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158338_k127_2119477_3	1333998.M2A_1972	3.287e-136	452.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,4BPB0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158338_k127_2119477_5	1144275.COCOR_00125	1.588e-105	365.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158338_k127_2119477_15	646529.Desaci_2993	1.736e-44	173.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,24BHT@186801|Clostridia,261MX@186807|Peptococcaceae	186801|Clostridia	I	PFAM Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158338_k127_2119477_25	1382306.JNIM01000001_gene3560	6.745e-18	89.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158338_k127_2119477_1	518766.Rmar_2012	8.078e-244	771.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158338_k127_2119477_22	309801.trd_A0193	2.926e-26	116.0	COG4314@1|root,COG4314@2|Bacteria,2G8NV@200795|Chloroflexi,27Z7G@189775|Thermomicrobia	189775|Thermomicrobia	C	lipoprotein involved in nitrous oxide reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2119477_10	479434.Sthe_0737	1.648e-73	267.0	COG1131@1|root,COG3420@1|root,COG1131@2|Bacteria,COG3420@2|Bacteria,2G7PN@200795|Chloroflexi,27Z0E@189775|Thermomicrobia	189775|Thermomicrobia	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	ABC_tran,NosD
SRR25158338_k127_2119477_12	926550.CLDAP_07180	2.688e-52	196.0	COG1131@1|root,COG1131@2|Bacteria,2G7PN@200795|Chloroflexi	200795|Chloroflexi	PV	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K07218	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,NosD
SRR25158338_k127_2119477_13	696281.Desru_1532	1.964e-47	180.0	COG1277@1|root,COG1277@2|Bacteria,1UZYB@1239|Firmicutes,24WAQ@186801|Clostridia,263UT@186807|Peptococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
SRR25158338_k127_2119477_28	368407.Memar_2420	8.313e-05	52.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2119477_9	439235.Dalk_0730	1.951e-89	317.0	COG0665@1|root,COG0665@2|Bacteria,1Q38Q@1224|Proteobacteria,43AQX@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158338_k127_2119477_26	36809.MAB_4089c	5.132e-13	78.0	COG1309@1|root,COG1309@2|Bacteria,2I8NQ@201174|Actinobacteria,23712@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158338_k127_2119477_20	1101190.ARWB01000001_gene3687	2.83e-30	135.0	COG1457@1|root,COG1457@2|Bacteria,1PYF6@1224|Proteobacteria,2VFVZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
SRR25158338_k127_2119477_7	96561.Dole_0194	6.566e-97	323.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158338_k127_2133109_10	439235.Dalk_3909	1.551e-28	121.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QX@1224|Proteobacteria,431N8@68525|delta/epsilon subdivisions,2WWXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158338_k127_2133109_8	439235.Dalk_3908	1.37e-30	131.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QU@1224|Proteobacteria,431N3@68525|delta/epsilon subdivisions,2WWWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158338_k127_2133109_3	1002809.SSIL_2629	1.394e-77	274.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26E4T@186818|Planococcaceae	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158338_k127_2133109_4	1429916.X566_16090	4.023e-71	251.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,3JUD7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158338_k127_2133109_9	311424.DhcVS_464	1.02e-29	126.0	COG1670@1|root,COG1670@2|Bacteria,2GAMB@200795|Chloroflexi,34CRJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158338_k127_2133109_7	485913.Krac_12558	9.536e-33	133.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
SRR25158338_k127_2133109_5	1128421.JAGA01000002_gene1410	6.479e-53	199.0	COG1413@1|root,COG1413@2|Bacteria,2NR83@2323|unclassified Bacteria	2|Bacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158338_k127_2133109_2	311424.DhcVS_467	1.651e-125	415.0	COG0312@1|root,COG0312@2|Bacteria,2GANY@200795|Chloroflexi,34CWZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158338_k127_2133109_0	552811.Dehly_0371	2.025e-157	508.0	COG0312@1|root,COG0312@2|Bacteria,2GBVJ@200795|Chloroflexi,34CYG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158338_k127_2133109_6	555088.DealDRAFT_2145	1.058e-35	143.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,42K31@68298|Syntrophomonadaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158338_k127_2133109_1	525904.Tter_1758	9.044e-145	472.0	COG1160@1|root,COG1160@2|Bacteria,2NNTW@2323|unclassified Bacteria	2|Bacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.399,1.1.1.95	ko:K00058,ko:K03977	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147	-	-	-	KH_dom-like,MMR_HSR1
SRR25158338_k127_2133109_11	1123284.KB899047_gene1657	1.651e-06	56.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,26NVY@186821|Sporolactobacillaceae	91061|Bacilli	S	YbbR-like protein	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158338_k127_2157761_2	1049564.TevJSym_ad00590	1.582e-10	70.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1J68H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	MarC family integral membrane protein	yhgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158338_k127_2157761_0	596151.DesfrDRAFT_1240	1.874e-58	214.0	COG0730@1|root,COG0730@2|Bacteria,1Q59Y@1224|Proteobacteria,430VR@68525|delta/epsilon subdivisions,2WVKN@28221|Deltaproteobacteria,2M8GD@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158338_k127_2157761_3	118168.MC7420_2459	0.0001533	51.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1G17W@1117|Cyanobacteria,1H8ZH@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158338_k127_2157761_1	502025.Hoch_2176	7.463e-12	77.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2171069_0	255470.cbdbA4	6.82e-259	811.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi,34D61@301297|Dehalococcoidia	301297|Dehalococcoidia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158338_k127_2171069_1	1123277.KB893177_gene3658	1.294e-38	152.0	COG0454@1|root,COG0456@2|Bacteria,4NU6N@976|Bacteroidetes,47VGZ@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_2197999_1	1123229.AUBC01000026_gene4075	1.041e-60	220.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,2TW0V@28211|Alphaproteobacteria,3JS8Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_25205	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	SEC-C,adh_short
SRR25158338_k127_2197999_2	298655.KI912266_gene633	2.05e-51	194.0	COG4221@1|root,COG4221@2|Bacteria,2GNFD@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_2197999_3	1394178.AWOO02000060_gene528	3.787e-35	147.0	2DMP1@1|root,32SS8@2|Bacteria,2IJVX@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SRR25158338_k127_2197999_0	264732.Moth_1517	6.971e-128	424.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158338_k127_2257657_1	1382356.JQMP01000004_gene65	3.368e-142	464.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,27XK6@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158338_k127_2257657_4	1209989.TepiRe1_2341	1.095e-65	232.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,42ENY@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRR25158338_k127_2257657_8	1120949.KB903317_gene1724	9.475e-31	132.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4DIVE@85008|Micromonosporales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158338_k127_2257657_7	479434.Sthe_3325	3.812e-35	145.0	COG0671@1|root,COG0671@2|Bacteria,2GB9M@200795|Chloroflexi,27YCA@189775|Thermomicrobia	189775|Thermomicrobia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158338_k127_2257657_13	1336208.JADY01000025_gene2441	0.0007542	50.0	2DM07@1|root,31400@2|Bacteria,1RDFQ@1224|Proteobacteria,2U8CE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2257657_12	671143.DAMO_1513	4.301e-20	97.0	COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_Tnp_IS630
SRR25158338_k127_2257657_11	243164.DET1031	5.189e-22	104.0	COG0645@1|root,COG0645@2|Bacteria,2GBGC@200795|Chloroflexi,34CRH@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158338_k127_2257657_6	255470.cbdbA1004	5.59e-40	159.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,34D2V@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Dihydroxyacetone kinase family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158338_k127_2257657_10	760568.Desku_2536	1.296e-25	108.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,262DU@186807|Peptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158338_k127_2257657_0	498761.HM1_2322	6.763e-251	799.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158338_k127_2257657_5	562970.Btus_1697	2.585e-64	230.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,277X7@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22490	DapB_C,DapB_N
SRR25158338_k127_2257657_3	1255043.TVNIR_1705	1.425e-97	332.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158338_k127_2257657_9	1121272.KB903272_gene472	1.142e-27	121.0	COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,4DA2C@85008|Micromonosporales	201174|Actinobacteria	CK	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158338_k127_2257657_2	552811.Dehly_0532	9.195e-125	408.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,34CM5@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158338_k127_2297043_2	243164.DET0739	7.455e-178	564.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi,34D2W@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158338_k127_2297043_6	1144275.COCOR_05742	2.557e-47	178.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria,2Z1HI@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158338_k127_2297043_3	479434.Sthe_1950	3.171e-149	496.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158338_k127_2297043_8	118166.JH976538_gene4994	2.3e-37	150.0	COG0500@1|root,COG2226@2|Bacteria,1G0TQ@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158338_k127_2297043_4	671143.DAMO_1028	3.51e-93	320.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47,6.1.1.16	ko:K01883,ko:K12339,ko:K21148	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859,R10610	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	PALP,tRNA-synt_1e
SRR25158338_k127_2297043_11	232721.Ajs_2721	0.0002469	51.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSS8@28216|Betaproteobacteria,4ADI5@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Blue (type 1) copper domain	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158338_k127_2297043_9	525904.Tter_0754	8.989e-27	116.0	298YA@1|root,32VWC@2|Bacteria,2NRHS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158338_k127_2297043_10	1163617.SCD_n00451	2.005e-12	74.0	COG5592@1|root,COG5592@2|Bacteria,1N4TJ@1224|Proteobacteria,2VU5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158338_k127_2297043_1	1382359.JIAL01000001_gene639	3.771e-218	685.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria,2JI0J@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158338_k127_2297043_5	292459.STH2115	1.382e-67	238.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158338_k127_2297043_7	1382306.JNIM01000001_gene2643	1.267e-41	162.0	COG1321@1|root,COG1321@2|Bacteria,2G7DY@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158338_k127_2297043_0	1382306.JNIM01000001_gene2570	4.902e-246	772.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158338_k127_2387389_5	246194.CHY_0161	6.545e-07	55.0	29Y0M@1|root,30JTI@2|Bacteria,1V50V@1239|Firmicutes,24GAX@186801|Clostridia,42G5J@68295|Thermoanaerobacterales	186801|Clostridia	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158338_k127_2387389_1	926569.ANT_04770	1.093e-76	291.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
SRR25158338_k127_2387389_4	234267.Acid_6160	3.064e-26	120.0	COG2340@1|root,COG4733@1|root,COG2340@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta_helix,CAP,PKD,fn3
SRR25158338_k127_2387389_3	566466.NOR53_2628	2.136e-40	162.0	COG1024@1|root,COG1024@2|Bacteria,1NJ9M@1224|Proteobacteria,1SMR0@1236|Gammaproteobacteria,1J9KU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158338_k127_2387389_2	234267.Acid_2815	4.75e-76	270.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158338_k127_2387389_0	357808.RoseRS_2477	5.248e-78	269.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi,3768D@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158338_k127_2397894_4	1137269.AZWL01000002_gene6273	3.855e-79	278.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158338_k127_2397894_0	1382356.JQMP01000004_gene634	3.846e-271	848.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,27Y4Z@189775|Thermomicrobia	189775|Thermomicrobia	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158338_k127_2397894_9	326427.Cagg_2695	2.364e-41	163.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi,375MV@32061|Chloroflexia	32061|Chloroflexia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158338_k127_2397894_5	485913.Krac_8356	3.444e-73	258.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158338_k127_2397894_7	255470.cbdbA1363	9.663e-62	219.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,34D5Y@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158338_k127_2397894_13	1340434.AXVA01000012_gene3021	9.947e-05	54.0	COG2755@1|root,COG2755@2|Bacteria,1VIQE@1239|Firmicutes,4IIKB@91061|Bacilli,1ZEN2@1386|Bacillus	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,Lipase_GDSL_2
SRR25158338_k127_2397894_8	292459.STH2132	1.566e-44	177.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia	186801|Clostridia	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
SRR25158338_k127_2397894_2	479434.Sthe_1003	1.507e-171	548.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158338_k127_2397894_12	261292.Nit79A3_1132	1.335e-05	55.0	2E0BD@1|root,32VYM@2|Bacteria,1N2FT@1224|Proteobacteria,2WD2I@28216|Betaproteobacteria,373XW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRR25158338_k127_2397894_1	255470.cbdbA1371	6.579e-226	712.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,34CRC@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158338_k127_2397894_3	105425.BBPL01000078_gene4746	1.149e-90	313.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,2NGPG@228398|Streptacidiphilus	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158338_k127_2397894_6	1382306.JNIM01000001_gene3013	2.246e-63	227.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158338_k127_2397894_11	521045.Kole_0436	1.046e-06	59.0	2DUHG@1|root,33QNU@2|Bacteria,2GDRM@200918|Thermotogae	200918|Thermotogae	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158338_k127_2397894_10	1408422.JHYF01000003_gene792	1.953e-15	83.0	2ENX9@1|root,33GI7@2|Bacteria,1VKAX@1239|Firmicutes,24TFB@186801|Clostridia,36N0K@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3221)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3221
SRR25158338_k127_2426162_2	1183438.GKIL_1904	1.243e-52	188.0	COG0745@1|root,COG0745@2|Bacteria,1G16W@1117|Cyanobacteria	1117|Cyanobacteria	K	Two component transcriptional regulator, Winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_2426162_0	871968.DESME_13010	7.006e-290	915.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,260B9@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158338_k127_2426162_4	512565.AMIS_35280	1.763e-14	79.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,4DFJX@85008|Micromonosporales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158338_k127_2426162_3	455632.SGR_620	1.533e-16	84.0	COG3795@1|root,COG3795@2|Bacteria,2HQVW@201174|Actinobacteria,41CYB@629295|Streptomyces griseus group	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158338_k127_2426162_1	861299.J421_2146	7.402e-78	265.0	COG4941@1|root,COG4941@2|Bacteria	2|Bacteria	K	sigma factor activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158338_k127_2435141_5	1002809.SSIL_1838	7.307e-35	149.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HF06@91061|Bacilli,26H34@186818|Planococcaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158338_k127_2435141_1	479434.Sthe_0724	1.657e-93	319.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158338_k127_2435141_7	383372.Rcas_3118	4.566e-10	69.0	COG3707@1|root,COG3707@2|Bacteria,2G6CD@200795|Chloroflexi,376C7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158338_k127_2435141_2	926550.CLDAP_28550	1.334e-85	297.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158338_k127_2435141_3	555088.DealDRAFT_1085	2.84e-71	246.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24G53@186801|Clostridia,42JVS@68298|Syntrophomonadaceae	186801|Clostridia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158338_k127_2435141_6	335543.Sfum_0171	2.38e-30	127.0	COG2524@1|root,COG2524@2|Bacteria,1QZ3Z@1224|Proteobacteria,430FG@68525|delta/epsilon subdivisions,2WW4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158338_k127_2435141_0	96561.Dole_1549	8.185e-104	347.0	COG1028@1|root,COG2030@1|root,COG3255@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,COG3255@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
SRR25158338_k127_2435141_4	1333998.M2A_2793	4.483e-52	191.0	COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,2U8BE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158338_k127_2453513_7	342113.DM82_1967	8.817e-22	98.0	COG2151@1|root,COG2151@2|Bacteria,1NAVI@1224|Proteobacteria,2WFKF@28216|Betaproteobacteria,1KI3A@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158338_k127_2453513_6	1206732.BAGD01000071_gene2751	1.996e-69	250.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4FZDF@85025|Nocardiaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158338_k127_2453513_3	1121422.AUMW01000014_gene1319	1.119e-136	447.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_2453513_2	335543.Sfum_3056	6.059e-140	455.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2MQ7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158338_k127_2453513_8	34007.IT40_00800	7.732e-07	52.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2PUKE@265|Paracoccus	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158338_k127_2453513_0	96561.Dole_0194	3.713e-232	749.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158338_k127_2453513_1	1123504.JQKD01000045_gene2105	5.557e-143	480.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VI39@28216|Betaproteobacteria,4AJ2P@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158338_k127_2453513_4	66377.JOBH01000012_gene4283	2.186e-131	430.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158338_k127_2453513_5	1434929.X946_727	1.229e-73	258.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VPTU@28216|Betaproteobacteria,1KDJU@119060|Burkholderiaceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinase, N-terminal domain protein	xylB2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158338_k127_2467866_2	760568.Desku_0403	4.713e-197	631.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158338_k127_2467866_30	59925.EU91_0463	5.027e-27	114.0	COG0838@1|root,COG0838@2|Bacteria,1G5RH@1117|Cyanobacteria,1MMCQ@1212|Prochloraceae	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
SRR25158338_k127_2467866_21	562970.Btus_3230	1.169e-56	204.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4HACH@91061|Bacilli,277Y1@186823|Alicyclobacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158338_k127_2467866_34	1434325.AZQN01000003_gene2097	2.07e-25	119.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,47PAN@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158338_k127_2467866_9	926569.ANT_18230	1.96e-114	380.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SRR25158338_k127_2467866_17	401526.TcarDRAFT_1932	2.002e-80	281.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,4H24V@909932|Negativicutes	909932|Negativicutes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158338_k127_2467866_38	471852.Tcur_4383	5.949e-18	98.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,4EIIP@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158338_k127_2467866_31	264732.Moth_0983	1.046e-26	115.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,24NAC@186801|Clostridia,42GTX@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158338_k127_2467866_35	1009370.ALO_00265	9.095e-25	108.0	COG0713@1|root,COG0713@2|Bacteria,1V9Z8@1239|Firmicutes,4H56S@909932|Negativicutes	909932|Negativicutes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158338_k127_2467866_7	1121423.JONT01000009_gene1483	6.033e-123	417.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,24A16@186801|Clostridia,2618I@186807|Peptococcaceae	186801|Clostridia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5	ndhF	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158338_k127_2467866_5	545243.BAEV01000010_gene1097	6.116e-136	448.0	COG1008@1|root,COG1008@2|Bacteria,1UHSH@1239|Firmicutes,24AAH@186801|Clostridia,36UKY@31979|Clostridiaceae	186801|Clostridia	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158338_k127_2467866_12	1121430.JMLG01000028_gene1463	9.634e-95	328.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158338_k127_2467866_43	103733.JNYO01000018_gene3291	5.471e-07	61.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria,2IQET@201174|Actinobacteria,4EEFR@85010|Pseudonocardiales	201174|Actinobacteria	MT	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158338_k127_2467866_1	311424.DhcVS_941	9.872e-206	648.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,34CUT@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158338_k127_2467866_0	1038869.AXAN01000048_gene4514	4.417e-221	694.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VZW7@28216|Betaproteobacteria,1K2N1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158338_k127_2467866_27	523845.AQXV01000040_gene1700	1.039e-38	147.0	COG0347@1|root,arCOG02305@2157|Archaea,2XYN5@28890|Euryarchaeota,23R3U@183939|Methanococci	183939|Methanococci	E	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158338_k127_2467866_3	671143.DAMO_1683	9.138e-145	471.0	COG0004@1|root,COG0004@2|Bacteria,2NQS8@2323|unclassified Bacteria	2|Bacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iHN637.CLJU_c42670,iYO844.BSU36510	Ammonium_transp
SRR25158338_k127_2467866_29	3067.XP_002946724.1	3.65e-31	132.0	KOG2847@1|root,KOG2847@2759|Eukaryota,37I0T@33090|Viridiplantae,34JHR@3041|Chlorophyta	3041|Chlorophyta	I	Phosphate acyltransferases	-	-	-	ko:K13511	ko00564,map00564	-	R09037	RC00004,RC00037	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158338_k127_2467866_18	929703.KE386491_gene2187	1.41e-78	272.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes,47PJY@768503|Cytophagia	976|Bacteroidetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158338_k127_2467866_28	552811.Dehly_0985	1.881e-38	153.0	COG0745@1|root,COG0745@2|Bacteria,2GARH@200795|Chloroflexi,34D69@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Trans_reg_C
SRR25158338_k127_2467866_8	926550.CLDAP_12660	3.034e-117	387.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158338_k127_2467866_11	255470.cbdbA1724	1.455e-95	333.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2G5QY@200795|Chloroflexi,34CTF@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158338_k127_2467866_24	357808.RoseRS_2438	2.212e-50	194.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi,375NH@32061|Chloroflexia	32061|Chloroflexia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
SRR25158338_k127_2467866_22	926569.ANT_04560	4.24e-56	213.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158338_k127_2467866_20	1123024.AUII01000052_gene3914	6.829e-67	233.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158338_k127_2467866_16	1313172.YM304_16610	1.086e-88	321.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2467866_4	706587.Desti_0176	8.417e-144	461.0	COG0214@1|root,COG0214@2|Bacteria,1MXHW@1224|Proteobacteria,42MNV@68525|delta/epsilon subdivisions,2WKCJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158338_k127_2467866_32	1283283.ATXA01000016_gene59	2.885e-26	119.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158338_k127_2467866_23	1121272.KB903253_gene6927	4.047e-53	198.0	COG0702@1|root,COG0702@2|Bacteria,2IT8A@201174|Actinobacteria,4DH5S@85008|Micromonosporales	201174|Actinobacteria	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158338_k127_2467866_6	240015.ACP_0692	1.653e-128	436.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C,GMC_oxred_N,NAD_binding_8,Pyr_redox_2
SRR25158338_k127_2467866_36	324602.Caur_0190	2.008e-22	109.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158338_k127_2467866_14	485913.Krac_6667	6.966e-92	309.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
SRR25158338_k127_2467866_25	292459.STH3147	8.288e-46	178.0	COG1290@1|root,COG1290@2|Bacteria,1USWS@1239|Firmicutes,2501X@186801|Clostridia	186801|Clostridia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158338_k127_2467866_33	644966.Tmar_0323	5.912e-26	117.0	COG0723@1|root,COG0723@2|Bacteria,1VM4K@1239|Firmicutes,24X5X@186801|Clostridia	186801|Clostridia	C	PFAM Rieske 2Fe-2S domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158338_k127_2467866_41	644966.Tmar_0321	2.589e-09	69.0	COG2010@1|root,COG2010@2|Bacteria,1VX6C@1239|Firmicutes,251IR@186801|Clostridia	186801|Clostridia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158338_k127_2467866_44	477641.MODMU_1943	8.98e-05	51.0	COG3794@1|root,COG3794@2|Bacteria,2H13T@201174|Actinobacteria,4EX0U@85013|Frankiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158338_k127_2467866_10	338963.Pcar_2038	1.422e-113	396.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43S8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158338_k127_2467866_13	1121468.AUBR01000032_gene1192	3.19e-94	318.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158338_k127_2467866_26	1173026.Glo7428_0367	1.785e-40	152.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158338_k127_2467866_39	1497679.EP56_04905	2.027e-14	77.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,4HKJV@91061|Bacilli,26N3P@186820|Listeriaceae	91061|Bacilli	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158338_k127_2467866_37	66377.JOBH01000023_gene3513	3.622e-20	99.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158338_k127_2467866_15	1121472.AQWN01000002_gene2329	8.326e-92	313.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158338_k127_2467866_19	311424.DhcVS_486	1.571e-67	239.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,34D40@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158338_k127_2492807_2	326427.Cagg_2564	7.489e-132	427.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158338_k127_2492807_4	388413.ALPR1_14479	8.976e-70	256.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
SRR25158338_k127_2492807_9	317936.Nos7107_0896	1.373e-07	62.0	2A293@1|root,30QJU@2|Bacteria,1G5ZB@1117|Cyanobacteria,1HNQR@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2492807_11	1463917.JODC01000015_gene1721	0.0006995	49.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158338_k127_2492807_7	1449069.JMLO01000012_gene5171	2.879e-22	104.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4FVU8@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1647	Guanylate_cyc
SRR25158338_k127_2492807_6	1333998.M2A_3080	4.065e-37	150.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,4BPI2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158338_k127_2492807_1	552811.Dehly_1020	7.6e-205	651.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,34CN0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158338_k127_2492807_0	311424.DhcVS_1051	1.741e-220	714.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,34D01@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158338_k127_2492807_5	243164.DET0421	8.737e-63	226.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,34CM9@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158338_k127_2492807_3	311424.DhcVS_1046	1.465e-125	421.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi,34CPP@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158338_k127_2492807_8	357808.RoseRS_3523	1.634e-16	86.0	COG0227@1|root,COG0227@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158338_k127_2492807_10	869210.Marky_0919	0.0004132	43.0	COG0036@1|root,COG0036@2|Bacteria,1WI8K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158338_k127_2511674_5	483219.LILAB_33085	2.426e-29	125.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158338_k127_2511674_7	42256.RradSPS_0390	6.15e-16	80.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	ThiS
SRR25158338_k127_2511674_3	479434.Sthe_0748	9.081e-40	152.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158338_k127_2511674_0	1120936.KB907225_gene2778	4.73e-128	422.0	COG2124@1|root,COG2124@2|Bacteria,2HMMY@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158338_k127_2511674_6	1297865.APJD01000005_gene3570	1.128e-17	94.0	COG1141@1|root,COG1141@2|Bacteria,1MZJU@1224|Proteobacteria,2UCKK@28211|Alphaproteobacteria,3K07G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	MA20_16570	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
SRR25158338_k127_2511674_1	368407.Memar_1826	1.267e-114	383.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,2N9VR@224756|Methanomicrobia	224756|Methanomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158338_k127_2511674_4	1283300.ATXB01000002_gene2873	5.661e-39	151.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1XGDH@135618|Methylococcales	135618|Methylococcales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
SRR25158338_k127_2511674_2	47839.CCAU010000011_gene5318	1.45e-101	337.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria,23ACA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158338_k127_2523807_2	1123371.ATXH01000006_gene831	1.238e-98	331.0	COG0165@1|root,COG0165@2|Bacteria,2GGV2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158338_k127_2523807_0	1173022.Cri9333_0749	3.589e-155	495.0	COG0667@1|root,COG0667@2|Bacteria,1G3WV@1117|Cyanobacteria,1HH84@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158338_k127_2523807_5	1131269.AQVV01000003_gene761	8.282e-18	93.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158338_k127_2523807_3	525904.Tter_2866	4.684e-64	229.0	COG0726@1|root,COG3103@1|root,COG0726@2|Bacteria,COG4991@2|Bacteria,2NPV2@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	pdaA	-	3.5.1.104,3.5.1.28	ko:K01448,ko:K22278	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,LysM,Polysacc_deac_1,SH3_3
SRR25158338_k127_2523807_4	756883.Halar_1892	1.04e-37	148.0	COG2258@1|root,arCOG11383@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158338_k127_2523807_1	552811.Dehly_0932	4.654e-152	491.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi,34CSW@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158338_k127_2542380_0	316274.Haur_2776	1.357e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,375U2@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158338_k127_2542380_1	255470.cbdbA1297	9.344e-07	62.0	2EMMB@1|root,33F9Q@2|Bacteria,2G9IY@200795|Chloroflexi,34D9F@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2578067_3	485913.Krac_2496	3.442e-38	151.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158338_k127_2578067_1	485913.Krac_10957	4.475e-45	178.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158338_k127_2578067_4	439235.Dalk_4916	4.541e-19	96.0	COG1102@1|root,COG1102@2|Bacteria,1N69V@1224|Proteobacteria,42VW2@68525|delta/epsilon subdivisions,2X5RD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
SRR25158338_k127_2578067_7	1313172.YM304_28640	2.362e-08	63.0	2968S@1|root,2ZTIT@2|Bacteria,2HEBZ@201174|Actinobacteria,4CNCH@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2578067_2	63737.Npun_F4016	7.278e-44	165.0	COG0698@1|root,COG0698@2|Bacteria,1G9WT@1117|Cyanobacteria,1HS96@1161|Nostocales	1117|Cyanobacteria	G	TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158338_k127_2578067_8	399550.Smar_0130	3.092e-07	61.0	COG4353@1|root,arCOG01699@2157|Archaea,2XR1F@28889|Crenarchaeota	28889|Crenarchaeota	S	uncharacterised conserved protein UCP017998	-	-	-	-	-	-	-	-	-	-	-	-	DUF1122
SRR25158338_k127_2578067_0	330214.NIDE2031	3.092e-175	556.0	COG1980@1|root,COG1980@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
SRR25158338_k127_257974_8	1265505.ATUG01000001_gene4392	2.46e-35	143.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
SRR25158338_k127_257974_7	1265505.ATUG01000001_gene4392	4.805e-40	155.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
SRR25158338_k127_257974_13	96561.Dole_0430	1.217e-05	53.0	COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158338_k127_257974_11	398580.Dshi_2965	7.863e-13	71.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR25158338_k127_257974_9	768710.DesyoDRAFT_1517	1.899e-27	120.0	COG1595@1|root,COG1595@2|Bacteria,1VFDK@1239|Firmicutes,24SE4@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158338_k127_257974_12	1123024.AUII01000002_gene1084	3.289e-08	55.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2I75H@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_257974_6	479434.Sthe_2942	2.474e-61	220.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi,27YB5@189775|Thermomicrobia	189775|Thermomicrobia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158338_k127_257974_5	1128421.JAGA01000003_gene2742	1.863e-64	227.0	COG1309@1|root,COG1309@2|Bacteria,2NRTD@2323|unclassified Bacteria	2|Bacteria	K	YsiA-like protein, C-terminal region	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TetR_C_4,TetR_N
SRR25158338_k127_257974_2	479434.Sthe_3025	5.242e-98	342.0	COG1169@1|root,COG1169@2|Bacteria,2GADW@200795|Chloroflexi,27Y2P@189775|Thermomicrobia	189775|Thermomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158338_k127_257974_0	479434.Sthe_3024	6.239e-207	660.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158338_k127_257974_3	479434.Sthe_3023	6.54e-92	311.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi,27Y8T@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158338_k127_257974_1	485913.Krac_8115	2.379e-138	444.0	COG0447@1|root,COG0447@2|Bacteria,2G66W@200795|Chloroflexi	200795|Chloroflexi	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158338_k127_257974_4	383372.Rcas_2084	3.161e-81	279.0	COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi,376AE@32061|Chloroflexia	32061|Chloroflexia	H	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158338_k127_260864_2	1384057.CD33_18450	1.831e-45	168.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3IWAD@400634|Lysinibacillus	91061|Bacilli	M	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158338_k127_260864_5	1382315.JPOI01000001_gene826	1.725e-27	124.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1WFKB@129337|Geobacillus	91061|Bacilli	S	G5	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
SRR25158338_k127_260864_0	926569.ANT_03800	1.281e-53	202.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158338_k127_260864_1	255470.cbdbA356	4.735e-52	198.0	COG1947@1|root,COG1947@2|Bacteria,2G71D@200795|Chloroflexi,34CZT@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158338_k127_260864_4	933262.AXAM01000004_gene2383	8.054e-38	151.0	COG0613@1|root,COG0613@2|Bacteria,1NFVB@1224|Proteobacteria,43BBY@68525|delta/epsilon subdivisions,2X6R1@28221|Deltaproteobacteria,2MPIB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	APH,DUF2889,PHP_C
SRR25158338_k127_260864_3	1128421.JAGA01000002_gene650	2.608e-43	169.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2NNYS@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III, epsilon subunit	dinG	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
SRR25158338_k127_2633759_1	357808.RoseRS_2950	7.624e-51	188.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,374VI@32061|Chloroflexia	32061|Chloroflexia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158338_k127_2633759_2	333138.LQ50_16160	3.818e-14	83.0	COG1266@1|root,COG1266@2|Bacteria,1UUMR@1239|Firmicutes,4HDXH@91061|Bacilli,1ZCN4@1386|Bacillus	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158338_k127_2633759_3	1269813.ATUL01000016_gene3	0.0001596	53.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158338_k127_2633759_0	1128421.JAGA01000001_gene2064	1.135e-107	364.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N,PRC
SRR25158338_k127_2644827_18	1128421.JAGA01000002_gene723	2.779e-43	165.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158338_k127_2644827_9	479434.Sthe_1063	1.621e-63	226.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi,27XMY@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	-	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158338_k127_2644827_13	485913.Krac_12503	2.104e-53	193.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158338_k127_2644827_15	1031288.AXAA01000031_gene115	1.214e-45	168.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,36IR2@31979|Clostridiaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158338_k127_2644827_29	237368.SCABRO_03483	1.056e-10	62.0	COG0257@1|root,COG0257@2|Bacteria,2J1IK@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158338_k127_2644827_22	1121105.ATXL01000016_gene1634	1.147e-33	130.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,4B3E0@81852|Enterococcaceae	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158338_k127_2644827_3	1120973.AQXL01000112_gene1094	1.268e-88	299.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158338_k127_2644827_7	1410625.JHWK01000004_gene820	5.495e-70	243.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,27IND@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
SRR25158338_k127_2644827_1	479434.Sthe_1056	7.557e-128	427.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158338_k127_2644827_20	316274.Haur_4933	1.061e-35	144.0	COG0200@1|root,COG0200@2|Bacteria,2G6T9@200795|Chloroflexi,375PW@32061|Chloroflexia	32061|Chloroflexia	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158338_k127_2644827_28	552811.Dehly_1079	1.139e-13	76.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,34DIM@301297|Dehalococcoidia	301297|Dehalococcoidia	J	structural constituent of ribosome	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158338_k127_2644827_11	521098.Aaci_2694	1.083e-54	196.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,278WX@186823|Alicyclobacillaceae	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158338_k127_2644827_21	644966.Tmar_2279	2.475e-34	138.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WCK3@538999|Clostridiales incertae sedis	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158338_k127_2644827_8	335541.Swol_2318	2.078e-66	230.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,42JWP@68298|Syntrophomonadaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158338_k127_2644827_16	935948.KE386495_gene1498	3.291e-45	167.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,42G9H@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158338_k127_2644827_27	644966.Tmar_2282	2.31e-18	85.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3WDG8@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158338_k127_2644827_4	309801.trd_0972	2.249e-78	268.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi,27XMS@189775|Thermomicrobia	189775|Thermomicrobia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158338_k127_2644827_23	484019.THA_1226	5.863e-26	112.0	COG0198@1|root,COG0198@2|Bacteria,2GD31@200918|Thermotogae	200918|Thermotogae	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158338_k127_2644827_14	97139.C824_01092	1.059e-49	179.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158338_k127_2644827_26	867903.ThesuDRAFT_00568	3.504e-19	98.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WCNB@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158338_k127_2644827_30	552811.Dehly_1089	6.102e-09	62.0	COG0255@1|root,COG0255@2|Bacteria,2G7DB@200795|Chloroflexi,34DH7@301297|Dehalococcoidia	301297|Dehalococcoidia	J	structural constituent of ribosome	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158338_k127_2644827_10	561177.ANHYDRO_01828	3.032e-60	212.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,22H73@1570339|Peptoniphilaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158338_k127_2644827_5	357808.RoseRS_1179	2.391e-76	265.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi,3757R@32061|Chloroflexia	32061|Chloroflexia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158338_k127_2644827_24	552811.Dehly_1092	8.727e-25	108.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi,34DE4@301297|Dehalococcoidia	301297|Dehalococcoidia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158338_k127_2644827_19	525904.Tter_0719	5.087e-36	145.0	COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158338_k127_2644827_2	1304880.JAGB01000003_gene1207	3.903e-121	394.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158338_k127_2644827_25	1449126.JQKL01000050_gene2677	8.535e-22	97.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158338_k127_2644827_12	552811.Dehly_1096	5.821e-54	203.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,34CM4@301297|Dehalococcoidia	301297|Dehalococcoidia	J	50S ribosomal protein L4	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158338_k127_2644827_6	552811.Dehly_1097	5.273e-74	254.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,34D7B@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158338_k127_2644827_17	498761.HM1_1377	1.104e-44	163.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158338_k127_2644827_0	1120972.AUMH01000017_gene714	7.306e-271	848.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,2783X@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158338_k127_2705848_2	102129.Lepto7375DRAFT_0506	3.824e-74	256.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
SRR25158338_k127_2705848_4	1449068.JMLQ01000001_gene772	7.626e-13	74.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4FZM2@85025|Nocardiaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158338_k127_2705848_3	1122951.ATUE01000008_gene280	7.599e-20	94.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158338_k127_2705848_5	1122951.ATUE01000008_gene280	1.151e-10	65.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158338_k127_2705848_1	373903.Hore_14550	6.631e-77	274.0	COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes	1239|Firmicutes	G	ABC transporter, substratebinding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158338_k127_2705848_0	744872.Spica_0828	1.219e-83	288.0	COG1175@1|root,COG1175@2|Bacteria,2J5SW@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10233	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158338_k127_2856987_5	1167006.UWK_03485	3.323e-41	160.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158338_k127_2856987_3	555088.DealDRAFT_1345	1.291e-58	220.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,42JQC@68298|Syntrophomonadaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158338_k127_2856987_2	644966.Tmar_2181	2.335e-102	349.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158338_k127_2856987_7	1121861.KB899923_gene3391	2.043e-09	68.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,2JSSX@204441|Rhodospirillales	204441|Rhodospirillales	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158338_k127_2856987_0	1382306.JNIM01000001_gene41	5.801e-120	399.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158338_k127_2856987_1	373903.Hore_09130	2.55e-116	392.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WB4Z@53433|Halanaerobiales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158338_k127_2856987_6	882083.SacmaDRAFT_4667	6.198e-33	134.0	2BVHN@1|root,332R2@2|Bacteria,2IPM7@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158338_k127_2856987_4	243164.DET0344	7.755e-51	186.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi,34CXD@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158338_k127_2882812_0	2002.JOEQ01000026_gene370	1.419e-84	287.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EHHD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_2882812_2	1347369.CCAD010000080_gene3144	3.155e-54	205.0	COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,4HN9I@91061|Bacilli,1ZR05@1386|Bacillus	91061|Bacilli	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S15
SRR25158338_k127_2882812_5	661478.OP10G_0131	4.529e-06	52.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158338_k127_2882812_4	1504981.KO116_1197	1.482e-32	138.0	COG0589@1|root,COG0589@2|Bacteria,1NAHQ@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158338_k127_2882812_1	443255.SCLAV_p1227	2.781e-76	263.0	COG0596@1|root,COG0596@2|Bacteria,2GY3A@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158338_k127_2882812_6	641143.HMPREF9331_00659	3.091e-05	55.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia,1EQKX@1016|Capnocytophaga	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158338_k127_2882812_3	1313172.YM304_22410	3.017e-40	151.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4CMWM@84992|Acidimicrobiia	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_291672_11	404589.Anae109_0600	3.338e-14	76.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria	1224|Proteobacteria	K	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD
SRR25158338_k127_291672_5	1380386.JIAW01000014_gene2793	2.057e-43	176.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,23D0V@1762|Mycobacteriaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158338_k127_291672_0	479434.Sthe_3486	1.386e-195	631.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_291672_4	880072.Desac_2808	4.225e-60	224.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2MRAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158338_k127_291672_3	1382306.JNIM01000001_gene2677	3.284e-106	357.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
SRR25158338_k127_291672_2	357808.RoseRS_3466	1.111e-162	522.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi,3766F@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158338_k127_291672_12	309801.trd_A0257	7.158e-07	61.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158338_k127_291672_9	1124991.MU9_2132	1.937e-23	109.0	COG1051@1|root,COG1051@2|Bacteria,1N5QT@1224|Proteobacteria,1SABD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158338_k127_291672_7	717606.PaecuDRAFT_3189	3.559e-32	135.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,4HJS5@91061|Bacilli,276AA@186822|Paenibacillaceae	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158338_k127_291672_1	264732.Moth_0152	1.033e-169	546.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRR25158338_k127_291672_6	635013.TherJR_0229	4.461e-34	139.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,261HN@186807|Peptococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158338_k127_291672_13	1304284.L21TH_2223	0.0001391	55.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,36F9B@31979|Clostridiaceae	186801|Clostridia	S	Glycosyl hydrolases family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
SRR25158338_k127_291672_8	479434.Sthe_1886	1.643e-29	124.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi,27Y9Y@189775|Thermomicrobia	189775|Thermomicrobia	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158338_k127_291672_10	861454.HMPREF9099_01856	1.808e-22	98.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,27MNI@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158338_k127_2949323_1	797209.ZOD2009_20687	9.246e-107	373.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
SRR25158338_k127_2949323_3	639030.JHVA01000001_gene1853	5.151e-102	334.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158338_k127_2949323_2	886293.Sinac_0081	4.064e-102	336.0	COG4447@1|root,COG4447@2|Bacteria,2IXU6@203682|Planctomycetes	203682|Planctomycetes	L	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_2949323_9	512565.AMIS_17530	1.37e-33	137.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
SRR25158338_k127_2949323_8	861299.J421_0662	6.112e-39	149.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158338_k127_2949323_6	525904.Tter_1205	5.434e-48	186.0	COG1878@1|root,COG1878@2|Bacteria,2NPXV@2323|unclassified Bacteria	2|Bacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158338_k127_2949323_10	1128421.JAGA01000002_gene943	4.821e-20	102.0	COG2154@1|root,COG2154@2|Bacteria,2NQ7C@2323|unclassified Bacteria	2|Bacteria	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	3.5.4.33,4.2.1.96	ko:K01724,ko:K11991	ko00790,map00790	-	R04734,R10223	RC00477,RC01208	ko00000,ko00001,ko01000,ko03016,ko04147	-	-	-	Pterin_4a
SRR25158338_k127_2949323_4	311424.DhcVS_655	6.325e-102	349.0	COG0634@1|root,COG1102@1|root,COG2203@1|root,COG0634@2|Bacteria,COG1102@2|Bacteria,COG2203@2|Bacteria,2G6HX@200795|Chloroflexi,34D91@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	GAF_2,Pribosyltran
SRR25158338_k127_2949323_7	1535422.ND16A_3943	2.03e-44	172.0	COG0596@1|root,COG0596@2|Bacteria,1Q4C8@1224|Proteobacteria	1224|Proteobacteria	S	alpha, beta	MA20_23630	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_2949323_5	357808.RoseRS_3163	7.374e-89	306.0	COG3804@1|root,COG3804@2|Bacteria,2G7MJ@200795|Chloroflexi	200795|Chloroflexi	C	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRR25158338_k127_2949323_0	479434.Sthe_0306	5.147e-129	429.0	COG0001@1|root,COG0001@2|Bacteria,2G7UK@200795|Chloroflexi,27XN6@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158338_k127_3048711_14	479434.Sthe_3003	9.442e-60	220.0	COG1804@1|root,COG1804@2|Bacteria,2GABR@200795|Chloroflexi,27XHH@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158338_k127_3048711_29	536233.CLO_1001	1.205e-28	122.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,24GZP@186801|Clostridia,36HYP@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158338_k127_3048711_36	1240349.ANGC01000009_gene2757	4.869e-12	70.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,Penicillinase_R
SRR25158338_k127_3048711_28	589924.Ferp_0247	5.479e-33	142.0	COG0003@1|root,arCOG02849@2157|Archaea,2XT6V@28890|Euryarchaeota,246YH@183980|Archaeoglobi	183980|Archaeoglobi	D	Arsenite-activated ATPase ArsA	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158338_k127_3048711_37	1121439.dsat_2281	6.379e-06	50.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria,2MBM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158338_k127_3048711_30	479434.Sthe_2485	2.478e-28	117.0	COG1225@1|root,COG1225@2|Bacteria,2G95Y@200795|Chloroflexi,27YNE@189775|Thermomicrobia	189775|Thermomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158338_k127_3048711_25	1123371.ATXH01000010_gene741	2.365e-42	167.0	COG0616@1|root,COG0616@2|Bacteria,2GH6V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158338_k127_3048711_31	525368.HMPREF0591_0024	2.11e-19	95.0	2BZG6@1|root,2ZH9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3048711_21	562970.Btus_2700	1.049e-50	198.0	COG0425@1|root,COG0425@2|Bacteria,1VWCV@1239|Firmicutes,4HWKN@91061|Bacilli,279VZ@186823|Alicyclobacillaceae	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3048711_17	1121468.AUBR01000001_gene540	6.669e-56	203.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,42GFH@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Rhomboid family protein	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158338_k127_3048711_22	357808.RoseRS_1980	2.579e-49	182.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,3777D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158338_k127_3048711_13	292459.STH1933	1.701e-63	232.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia	186801|Clostridia	HP	Abc transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158338_k127_3048711_7	255470.cbdbA635	1.157e-84	295.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi,34CYV@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158338_k127_3048711_24	1273125.Rrhod_0691	1.169e-43	175.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria,4FW85@85025|Nocardiaceae	201174|Actinobacteria	P	Periplasmic binding protein	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158338_k127_3048711_10	485913.Krac_7281	9.281e-71	247.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_3048711_26	1002809.SSIL_1838	4.28e-41	173.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HF06@91061|Bacilli,26H34@186818|Planococcaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158338_k127_3048711_19	1227352.C173_05516	2.856e-54	206.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,26Q9W@186822|Paenibacillaceae	91061|Bacilli	EP	ABC transporter permease	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158338_k127_3048711_15	1038859.AXAU01000026_gene2331	2.314e-57	212.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRS8@28211|Alphaproteobacteria,3JS1M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	nikB	-	-	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158338_k127_3048711_11	1382356.JQMP01000004_gene175	5.224e-69	244.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27YS7@189775|Thermomicrobia	189775|Thermomicrobia	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158338_k127_3048711_20	525904.Tter_0837	9.439e-53	196.0	COG2120@1|root,COG2120@2|Bacteria,2NQ6H@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158338_k127_3048711_16	243164.DET1640	3.137e-56	204.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,34CY4@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158338_k127_3048711_5	1089553.Tph_c25300	2.243e-100	337.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,42F1U@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.24	ko:K02031,ko:K15583,ko:K15587	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158338_k127_3048711_3	237368.SCABRO_01399	7.656e-165	524.0	COG0473@1|root,COG0473@2|Bacteria,2IXJZ@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158338_k127_3048711_35	1077972.ARGLB_008_00440	1.544e-12	71.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158338_k127_3048711_4	187272.Mlg_2099	2.528e-113	372.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1WXFH@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SRR25158338_k127_3048711_9	102129.Lepto7375DRAFT_4117	3.671e-73	253.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria	1117|Cyanobacteria	S	Flavin-nucleotide-binding protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158338_k127_3048711_0	243164.DET0825	3.712e-184	594.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,34D2K@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158338_k127_3048711_32	485913.Krac_11841	3.837e-17	90.0	COG0671@1|root,COG0671@2|Bacteria,2G8YH@200795|Chloroflexi	200795|Chloroflexi	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158338_k127_3048711_34	278963.ATWD01000003_gene170	5.399e-13	77.0	COG1286@1|root,COG1286@2|Bacteria,3Y59W@57723|Acidobacteria,2JJP3@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
SRR25158338_k127_3048711_18	316274.Haur_4220	3.206e-55	198.0	COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia	32061|Chloroflexia	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158338_k127_3048711_27	1089553.Tph_c18080	1.02e-34	143.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,42G5U@68295|Thermoanaerobacterales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158338_k127_3048711_8	1128421.JAGA01000002_gene1561	5.928e-75	261.0	COG0077@1|root,COG0077@2|Bacteria,2NR2C@2323|unclassified Bacteria	2|Bacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158338_k127_3048711_12	311424.DhcVS_25	1.264e-66	233.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,34CKI@301297|Dehalococcoidia	301297|Dehalococcoidia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158338_k127_3048711_23	552811.Dehly_1508	1.1e-44	166.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,34DCB@301297|Dehalococcoidia	301297|Dehalococcoidia	C	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158338_k127_3048711_33	309801.trd_1480	1.281e-16	85.0	COG0589@1|root,COG0589@2|Bacteria,2G7D7@200795|Chloroflexi,27YGW@189775|Thermomicrobia	189775|Thermomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158338_k127_3048711_2	552811.Dehly_1425	8.88e-173	556.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,34CRG@301297|Dehalococcoidia	301297|Dehalococcoidia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158338_k127_3048711_6	243164.DET1416	1.089e-97	331.0	COG0150@1|root,COG0150@2|Bacteria,2G5YZ@200795|Chloroflexi,34D95@301297|Dehalococcoidia	301297|Dehalococcoidia	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158338_k127_3048711_1	479434.Sthe_1288	1.248e-173	557.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,27XUW@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
SRR25158338_k127_3061813_6	931627.MycrhDRAFT_5409	4.474e-09	59.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,238J1@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158338_k127_3061813_0	886293.Sinac_5675	2.448e-108	365.0	COG0128@1|root,COG0128@2|Bacteria,2IXRF@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158338_k127_3061813_4	316274.Haur_3653	9.807e-29	131.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3061813_5	1094980.Mpsy_2468	1.518e-15	85.0	arCOG05230@1|root,arCOG05230@2157|Archaea,2Y36Z@28890|Euryarchaeota,2NAJ8@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3061813_3	1117379.BABA_12101	1.155e-52	196.0	COG2267@1|root,COG2267@2|Bacteria,1UKWC@1239|Firmicutes,4ITKP@91061|Bacilli	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_3061813_2	1117379.BABA_12101	1.183e-55	204.0	COG2267@1|root,COG2267@2|Bacteria,1UKWC@1239|Firmicutes,4ITKP@91061|Bacilli	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_3061813_1	1259795.ARJK01000002_gene414	2.55e-62	223.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,24BBC@186801|Clostridia,42GNP@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	fabG4	-	1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76	ko:K00059,ko:K18009,ko:K19548	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R10917,R11671	RC00029,RC00117,RC00154,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_3090349_5	279010.BL02219	1.813e-57	209.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158338_k127_3090349_6	1382306.JNIM01000001_gene4168	5.355e-44	168.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158338_k127_3090349_4	760142.Hipma_1042	2.928e-72	253.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,2M6FU@213113|Desulfurellales	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
SRR25158338_k127_3090349_0	926569.ANT_16350	4.02e-193	620.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158338_k127_3090349_3	243164.DET0553	4.058e-116	384.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi,34CSV@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158338_k127_3090349_2	479434.Sthe_0414	1.842e-130	439.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia	189775|Thermomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158338_k127_3090349_1	552811.Dehly_0793	1.415e-131	436.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,34D2Y@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158338_k127_3090349_7	1449353.JQMQ01000005_gene154	1.995e-25	111.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria,2NITJ@228398|Streptacidiphilus	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	ypeA	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158338_k127_3090349_10	266117.Rxyl_2441	1.777e-11	74.0	2EP0Z@1|root,33GMU@2|Bacteria	2|Bacteria	K	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158338_k127_3090349_11	345341.KUTG_08512	2.131e-08	60.0	COG0617@1|root,COG0617@2|Bacteria,2HMMR@201174|Actinobacteria,4ECT9@85010|Pseudonocardiales	201174|Actinobacteria	J	tRNA 3'-terminal CCA addition	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3090349_8	500153.JOEK01000001_gene3723	1.902e-23	104.0	COG0617@1|root,COG0617@2|Bacteria,2IFKR@201174|Actinobacteria	201174|Actinobacteria	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
SRR25158338_k127_3090349_9	552811.Dehly_1579	3.077e-20	101.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi,34CJ2@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
SRR25158338_k127_3122639_4	1150599.MPHLEI_19345	3.609e-27	117.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,238M9@1762|Mycobacteriaceae	201174|Actinobacteria	S	metal-dependent protease of the Pad1 Jab1 superfamily	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158338_k127_3122639_2	671143.DAMO_1028	1.602e-112	371.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47,6.1.1.16	ko:K01883,ko:K12339,ko:K21148	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859,R10610	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	PALP,tRNA-synt_1e
SRR25158338_k127_3122639_5	351607.Acel_1688	4.637e-22	106.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4ESZV@85013|Frankiales	201174|Actinobacteria	H	PFAM thiamineS protein	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158338_k127_3122639_0	525904.Tter_1313	4.342e-139	455.0	COG0476@1|root,COG1977@1|root,COG0476@2|Bacteria,COG1977@2|Bacteria,2NPX3@2323|unclassified Bacteria	2|Bacteria	H	ThiF family	moeB	-	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRR25158338_k127_3122639_1	671143.DAMO_1023	5.208e-127	415.0	COG0031@1|root,COG0031@2|Bacteria,2NNTU@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK-1	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_3122639_3	485913.Krac_12539	1.154e-34	138.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158338_k127_3138945_1	222534.KB893738_gene1273	6.806e-159	512.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4ES3N@85013|Frankiales	201174|Actinobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
SRR25158338_k127_3138945_0	96561.Dole_0194	1.621e-261	835.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158338_k127_3138945_2	1206726.BAFV01000125_gene6584	1.103e-15	79.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4FYBZ@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_3154969_9	485913.Krac_10762	5.736e-05	46.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158338_k127_3154969_5	1382306.JNIM01000001_gene527	1.276e-49	186.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158338_k127_3154969_1	485913.Krac_10815	1.107e-147	479.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158338_k127_3154969_7	543728.Vapar_6180	1.787e-27	115.0	2AIPE@1|root,3195Z@2|Bacteria,1NRGR@1224|Proteobacteria	1224|Proteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158338_k127_3154969_0	311424.DhcVS_1164	3.635e-187	598.0	COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,34D0E@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158338_k127_3154969_6	906968.Trebr_0574	9.725e-35	145.0	COG0327@1|root,COG0327@2|Bacteria,2J9CQ@203691|Spirochaetes	203691|Spirochaetes	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158338_k127_3154969_3	479434.Sthe_2195	3.757e-62	224.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,27Z0A@189775|Thermomicrobia	189775|Thermomicrobia	H	Quinolinate phosphoribosyl transferase, N-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158338_k127_3154969_10	1396.DJ87_5671	6.366e-05	55.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,4IPKB@91061|Bacilli,1ZMEB@1386|Bacillus	91061|Bacilli	M	conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158338_k127_3154969_4	1200557.JHWV01000001_gene385	1.388e-51	188.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4H4M4@909932|Negativicutes	909932|Negativicutes	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158338_k127_3154969_2	767817.Desgi_1545	3.944e-72	258.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia,261F2@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
SRR25158338_k127_3154969_8	1906.SFRA_26500	2.268e-15	81.0	COG0739@1|root,COG1652@1|root,COG0739@2|Bacteria,COG1652@2|Bacteria,2GK68@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	LysM,Peptidase_M23,Transglycosylas
SRR25158338_k127_3308814_7	498761.HM1_0663	2.286e-47	181.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158338_k127_3308814_2	760568.Desku_1150	4.808e-115	388.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158338_k127_3308814_15	224914.BMEI0567	6.902e-07	57.0	2DQNQ@1|root,337TP@2|Bacteria,1NFYG@1224|Proteobacteria,2UFD8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3308814_9	644282.Deba_1407	2.672e-33	132.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158338_k127_3308814_11	543632.JOJL01000050_gene7462	4.139e-24	117.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4DM0R@85008|Micromonosporales	201174|Actinobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158338_k127_3308814_16	926560.KE387023_gene1679	2.338e-05	55.0	COG1579@1|root,COG1579@2|Bacteria,1WJTQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Zn-ribbon protein, possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158338_k127_3308814_10	1382306.JNIM01000001_gene3739	2.3e-25	113.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158338_k127_3308814_13	255470.cbdbA1203	1.542e-13	72.0	COG0333@1|root,COG0333@2|Bacteria,2G7EA@200795|Chloroflexi,34DHT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158338_k127_3308814_4	383372.Rcas_1491	2.269e-67	241.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,375EH@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158338_k127_3308814_3	429009.Adeg_0958	2.987e-80	274.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,42F9Z@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_3308814_8	309801.trd_1619	9.354e-35	144.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi,27YFI@189775|Thermomicrobia	189775|Thermomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158338_k127_3308814_12	1382306.JNIM01000001_gene3743	1.105e-22	99.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158338_k127_3308814_17	596320.NEIFL0001_1766	0.0003108	48.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KRXX@206351|Neisseriales	206351|Neisseriales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158338_k127_3308814_6	926550.CLDAP_15680	1.058e-48	184.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158338_k127_3308814_5	311424.DhcVS_379	2.408e-65	229.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,34CY0@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158338_k127_3308814_0	1382306.JNIM01000001_gene4079	5.289e-190	608.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158338_k127_3308814_1	552811.Dehly_0150	1.391e-161	538.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,34CZW@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
SRR25158338_k127_3308814_14	219305.MCAG_03382	5.483e-07	56.0	COG0454@1|root,COG0456@2|Bacteria,2IRF9@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SRR25158338_k127_336921_6	485913.Krac_12501	9.779e-48	181.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158338_k127_336921_7	311424.DhcVS_445	7.294e-42	156.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi,34DCI@301297|Dehalococcoidia	301297|Dehalococcoidia	J	structural constituent of ribosome	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158338_k127_336921_4	1125863.JAFN01000001_gene496	4.68e-54	201.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158338_k127_336921_5	1177154.Y5S_01385	6.193e-50	182.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XJIQ@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158338_k127_336921_8	867903.ThesuDRAFT_00593	1.143e-39	154.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WD8E@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158338_k127_336921_2	552811.Dehly_1064	9.641e-87	301.0	COG2222@1|root,COG2222@2|Bacteria,2G8HU@200795|Chloroflexi,34D2X@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR25158338_k127_336921_0	1128421.JAGA01000004_gene2629	3.709e-151	493.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158338_k127_336921_3	397948.Cmaq_0999	2.538e-66	233.0	COG1208@1|root,arCOG00663@2157|Archaea,2XPVR@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158338_k127_336921_1	351160.RRC334	2.213e-144	469.0	COG0192@1|root,arCOG07444@2157|Archaea	2157|Archaea	H	S-adenosylmethionine synthetase, C-terminal domain	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158338_k127_3399059_36	1304880.JAGB01000001_gene346	4.755e-05	54.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158338_k127_3399059_21	997346.HMPREF9374_3536	8.24e-51	201.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HCR1@91061|Bacilli,27CEN@186824|Thermoactinomycetaceae	91061|Bacilli	S	Peptidase family M28	ywaD	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
SRR25158338_k127_3399059_18	767817.Desgi_1585	6.004e-60	229.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,260IW@186807|Peptococcaceae	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158338_k127_3399059_16	390989.JOEG01000021_gene2674	1.585e-64	238.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4D9Q4@85008|Micromonosporales	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158338_k127_3399059_12	42256.RradSPS_1857	4.438e-74	259.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158338_k127_3399059_29	479434.Sthe_0630	3.377e-30	122.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi,27YGX@189775|Thermomicrobia	189775|Thermomicrobia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158338_k127_3399059_34	298655.KI912266_gene2526	1.097e-14	79.0	COG0633@1|root,COG0633@2|Bacteria,2GSER@201174|Actinobacteria,4EX1F@85013|Frankiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
SRR25158338_k127_3399059_32	1121403.AUCV01000008_gene1630	2.451e-18	89.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,42TER@68525|delta/epsilon subdivisions,2WPKW@28221|Deltaproteobacteria,2MK8J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158338_k127_3399059_37	1121116.KB894769_gene1404	0.0006313	48.0	COG0280@1|root,COG2030@1|root,COG0280@2|Bacteria,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,2WGKC@28216|Betaproteobacteria,4AASD@80864|Comamonadaceae	28216|Betaproteobacteria	CI	Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
SRR25158338_k127_3399059_30	760568.Desku_0341	9.257e-29	120.0	COG2030@1|root,COG2030@2|Bacteria,1V8MB@1239|Firmicutes,24WTT@186801|Clostridia,2639K@186807|Peptococcaceae	186801|Clostridia	I	PFAM MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158338_k127_3399059_4	1382356.JQMP01000001_gene1184	1.846e-153	495.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi,27Y13@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158338_k127_3399059_27	479434.Sthe_0834	1.305e-30	125.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi,27Z8E@189775|Thermomicrobia	189775|Thermomicrobia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158338_k127_3399059_24	1382306.JNIM01000001_gene4124	1.04e-33	146.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158338_k127_3399059_20	1283283.ATXA01000001_gene378	3.42e-52	194.0	COG0300@1|root,COG0300@2|Bacteria,2I5VJ@201174|Actinobacteria,4EXE8@85013|Frankiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_3399059_14	525368.HMPREF0591_0025	4.327e-72	257.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria,23B3Y@1762|Mycobacteriaceae	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3399059_0	56107.Cylst_2702	4.35e-184	585.0	COG3669@1|root,COG3669@2|Bacteria,1GBPE@1117|Cyanobacteria,1HIWH@1161|Nostocales	1117|Cyanobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
SRR25158338_k127_3399059_8	357808.RoseRS_3797	2.284e-107	364.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158338_k127_3399059_2	1382306.JNIM01000001_gene3478	2.918e-169	548.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
SRR25158338_k127_3399059_9	42256.RradSPS_2229	2.071e-105	351.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4CPYB@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_3399059_10	1211815.CBYP010000012_gene528	8.639e-97	328.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158338_k127_3399059_7	767817.Desgi_0669	6.616e-110	374.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia	186801|Clostridia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_3399059_23	682795.AciX8_2177	1.125e-38	154.0	COG0596@1|root,COG0596@2|Bacteria,3Y5W5@57723|Acidobacteria,2JKEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_3399059_13	1123504.JQKD01000012_gene1257	1.093e-72	272.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria,4AH2J@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA-transferase family III	bbsE	-	2.8.3.15	ko:K07543	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158338_k127_3399059_11	266117.Rxyl_2393	5.151e-87	295.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria	201174|Actinobacteria	IQ	reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_3399059_38	621372.ACIH01000146_gene40	0.0007209	48.0	COG2318@1|root,COG2318@2|Bacteria,1V95A@1239|Firmicutes,4HJF3@91061|Bacilli,26TKB@186822|Paenibacillaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158338_k127_3399059_35	370438.PTH_0088	2.553e-09	63.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,2614P@186807|Peptococcaceae	186801|Clostridia	M	Domain of unknown function (DUF3794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
SRR25158338_k127_3399059_19	861299.J421_0149	4.971e-53	194.0	COG0122@1|root,COG0122@2|Bacteria,1ZTST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158338_k127_3399059_1	1961.JOAK01000001_gene3230	1.547e-171	555.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158338_k127_3399059_3	406124.ACPC01000017_gene668	2.625e-157	506.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	atoB	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
SRR25158338_k127_3399059_26	671143.DAMO_2618	1.149e-30	126.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158338_k127_3399059_15	886293.Sinac_6848	2.107e-70	250.0	COG0451@1|root,COG0451@2|Bacteria,2J2KW@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158338_k127_3399059_17	196162.Noca_4065	2.884e-64	232.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_3399059_33	234267.Acid_3880	5.219e-15	82.0	COG1225@1|root,COG1225@2|Bacteria,3Y8N3@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158338_k127_3399059_28	1121422.AUMW01000025_gene349	2.201e-30	124.0	COG1278@1|root,COG1278@2|Bacteria,1VWWT@1239|Firmicutes,251UG@186801|Clostridia,265GV@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158338_k127_3399059_5	1449126.JQKL01000016_gene2873	3.191e-137	449.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia	186801|Clostridia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_3399059_6	491915.Aflv_1181	1.902e-123	407.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4IBJX@91061|Bacilli,21X7D@150247|Anoxybacillus	91061|Bacilli	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158338_k127_3399059_31	1089544.KB912942_gene4280	5.39e-28	122.0	COG4101@1|root,COG4101@2|Bacteria,2II11@201174|Actinobacteria,4E3SV@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR25158338_k127_3399059_25	485913.Krac_8126	1.248e-33	139.0	COG0406@1|root,COG0406@2|Bacteria,2G726@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158338_k127_3399059_22	797209.ZOD2009_14186	9.337e-51	190.0	COG1874@1|root,arCOG04085@2157|Archaea,2XSU6@28890|Euryarchaeota,23UX4@183963|Halobacteria	183963|Halobacteria	G	COG1874 Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3437764_20	909663.KI867150_gene399	1.058e-24	111.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MR16@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158338_k127_3437764_18	591157.SSLG_04023	3.535e-26	113.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158338_k127_3437764_11	1041139.KB902680_gene1766	3.977e-60	225.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,4BAPG@82115|Rhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158338_k127_3437764_19	1040982.AXAL01000011_gene1174	1.378e-25	109.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3437764_14	1041139.KB902680_gene1766	8.214e-50	194.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,4BAPG@82115|Rhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158338_k127_3437764_17	216594.MMAR_2788	6.507e-31	126.0	2AU5M@1|root,31JSH@2|Bacteria,2IJSM@201174|Actinobacteria,239KJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3437764_9	710111.FraQA3DRAFT_2348	1.284e-68	241.0	2ANI9@1|root,31DH5@2|Bacteria,2GJE8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3437764_0	479434.Sthe_2199	6.087e-162	535.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158338_k127_3437764_21	926554.KI912671_gene194	1.564e-19	95.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158338_k127_3437764_16	313594.PI23P_10892	1.472e-31	130.0	293MU@1|root,2ZR3M@2|Bacteria,4P1JC@976|Bacteroidetes,1I7IN@117743|Flavobacteriia	976|Bacteroidetes	S	Nickel-containing superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158338_k127_3437764_22	102232.GLO73106DRAFT_00004330	1.303e-15	82.0	COG0681@1|root,COG0681@2|Bacteria,1GA6F@1117|Cyanobacteria	1117|Cyanobacteria	U	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158338_k127_3437764_8	941449.dsx2_2880	4.867e-69	268.0	2CDBG@1|root,343FF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3437764_23	1123320.KB889730_gene5937	8.012e-15	90.0	2CH8M@1|root,348V3@2|Bacteria,2GTQ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3437764_3	477974.Daud_0617	7.763e-111	374.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,260R0@186807|Peptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRR25158338_k127_3437764_7	552811.Dehly_0196	9.554e-80	279.0	COG0750@1|root,COG0750@2|Bacteria,2G6HV@200795|Chloroflexi,34D8H@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158338_k127_3437764_2	243164.DET0371	1.179e-118	396.0	COG0743@1|root,COG0743@2|Bacteria,2G5RB@200795|Chloroflexi,34CVA@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158338_k127_3437764_15	525904.Tter_1515	4.572e-39	156.0	COG0575@1|root,COG0575@2|Bacteria,2NS5V@2323|unclassified Bacteria	2|Bacteria	I	Cytidylyltransferase family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1397	CTP_transf_1
SRR25158338_k127_3437764_6	309801.trd_1002	4.369e-87	296.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi,27XF1@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158338_k127_3437764_10	1123405.AUMM01000001_gene50	1.029e-62	220.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,26NSR@186821|Sporolactobacillaceae	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158338_k127_3437764_5	864563.HMPREF9166_0262	9.813e-88	297.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H26K@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158338_k127_3437764_12	644966.Tmar_1004	4.826e-53	192.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WD1V@538999|Clostridiales incertae sedis	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158338_k127_3437764_4	243164.DET0377	6.142e-88	304.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi,34D52@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158338_k127_3437764_24	1050202.KB913024_gene2819	5.531e-12	71.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,409ER@622450|Actinopolysporales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158338_k127_3437764_13	867845.KI911784_gene2238	5.01e-52	188.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,3778M@32061|Chloroflexia	32061|Chloroflexia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158338_k127_3437764_1	311424.DhcVS_971	1.848e-154	498.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2G63D@200795|Chloroflexi,34CNV@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158338_k127_3441108_3	269799.Gmet_2198	5.985e-59	213.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_3441108_0	247633.GP2143_17291	2.62e-103	350.0	COG1960@1|root,COG1960@2|Bacteria,1R6EH@1224|Proteobacteria,1RMXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_3441108_6	696281.Desru_2689	3.526e-16	80.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR25158338_k127_3441108_2	1206732.BAGD01000054_gene1961	2.115e-97	331.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_3441108_5	202952.BBLI01000010_gene968	8.584e-17	90.0	COG4912@1|root,COG4912@2|Bacteria,1QJE2@1224|Proteobacteria,1RMB7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158338_k127_3441108_4	251221.35210787	3.967e-32	129.0	COG5485@1|root,COG5485@2|Bacteria,1G6RM@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158338_k127_3441108_1	263358.VAB18032_03290	1.227e-102	347.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DEDW@85008|Micromonosporales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158338_k127_3470294_1	56107.Cylst_2362	1.003e-74	258.0	COG0535@1|root,COG0535@2|Bacteria,1G1TV@1117|Cyanobacteria,1HIHG@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
SRR25158338_k127_3470294_4	1268237.G114_11105	2.566e-09	68.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1Y45M@135624|Aeromonadales	135624|Aeromonadales	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158338_k127_3470294_0	1137271.AZUM01000001_gene1398	1.704e-217	692.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,4E0ZE@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Prenyltransferase and squalene oxidase repeat	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
SRR25158338_k127_3470294_5	82996.sch_13005	0.0003338	46.0	COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,40565@613|Serratia	1236|Gammaproteobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158338_k127_3470294_3	1248917.ANFX01000013_gene1500	2.377e-26	111.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales	204457|Sphingomonadales	S	FeS assembly SUF system protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158338_k127_3470294_2	1089545.KB913037_gene6191	3.514e-36	148.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DYBG@85010|Pseudonocardiales	201174|Actinobacteria	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
SRR25158338_k127_3470747_0	1121272.KB903250_gene2734	2.076e-223	702.0	COG1260@1|root,COG1260@2|Bacteria,2GJVN@201174|Actinobacteria	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158338_k127_3470747_1	479434.Sthe_1718	4.261e-49	187.0	COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi,27Y7M@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158338_k127_3470747_2	324602.Caur_3001	1.291e-41	166.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi,37789@32061|Chloroflexia	32061|Chloroflexia	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRR25158338_k127_3470747_3	1205910.B005_3737	1.712e-08	61.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4EGYP@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158338_k127_3477636_11	525904.Tter_2437	1.343e-13	81.0	COG1253@1|root,COG2823@1|root,COG1253@2|Bacteria,COG2823@2|Bacteria,2NQTV@2323|unclassified Bacteria	2|Bacteria	S	BON domain	MA20_45180	-	3.6.3.32	ko:K02000,ko:K03281,ko:K05794,ko:K05847,ko:K07089,ko:K07448	ko02010,map02010	M00208,M00209	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048	2.A.49,3.A.1.12	-	-	ABC_tran,BON,CBS,EAL,GGDEF,Voltage_CLC
SRR25158338_k127_3477636_4	436229.JOEH01000014_gene6189	8.741e-76	271.0	arCOG06766@1|root,2Z87F@2|Bacteria,2IAM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3477636_8	316067.Geob_3017	1.688e-38	153.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,43SZ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158338_k127_3477636_10	1382306.JNIM01000001_gene3902	1.428e-14	81.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3477636_5	1382356.JQMP01000003_gene2345	9.85e-73	259.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,27XQX@189775|Thermomicrobia	189775|Thermomicrobia	C	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158338_k127_3477636_9	243164.DET0036	1.6e-22	99.0	COG2052@1|root,COG2052@2|Bacteria,2GAV2@200795|Chloroflexi,34DEP@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF370)	-	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
SRR25158338_k127_3477636_6	648996.Theam_1402	8.765e-45	169.0	COG0194@1|root,COG0194@2|Bacteria,2G3ZQ@200783|Aquificae	200783|Aquificae	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158338_k127_3477636_0	525904.Tter_1475	5.898e-224	707.0	COG0366@1|root,COG0366@2|Bacteria,2NQFF@2323|unclassified Bacteria	2|Bacteria	G	Alpha-amylase domain	malL	-	3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
SRR25158338_k127_3477636_1	717605.Theco_3372	1.959e-202	639.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes	1239|Firmicutes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_3477636_3	383372.Rcas_2157	1.783e-123	405.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,3766S@32061|Chloroflexia	32061|Chloroflexia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158338_k127_3477636_2	479434.Sthe_1878	1.631e-170	550.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,27XZ8@189775|Thermomicrobia	189775|Thermomicrobia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158338_k127_3477636_7	1415166.NONO_c27140	1.163e-40	164.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	fabG7	-	1.1.1.100,1.1.1.401,1.1.1.53	ko:K00038,ko:K00059,ko:K07535,ko:K21883	ko00051,ko00061,ko00140,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00051,map00061,map00140,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04831,R04834,R04844,R04847,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11339,R11671	RC00029,RC00089,RC00117,RC00139,RC00154,RC01219,RC01220	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158338_k127_3551760_13	479435.Kfla_3996	1.755e-13	76.0	COG0346@1|root,COG0346@2|Bacteria,2INT0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3551760_0	243164.DET0337	2.557e-224	721.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,34D0F@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Helicase_C,ResIII
SRR25158338_k127_3551760_11	477974.Daud_0661	1.705e-40	159.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158338_k127_3551760_5	311424.DhcVS_280	4.233e-90	302.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi,34CK3@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158338_k127_3551760_10	1089553.Tph_c01650	7.345e-57	202.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42G8D@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SRR25158338_k127_3551760_12	324602.Caur_0764	1.078e-22	102.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,3778H@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158338_k127_3551760_1	255470.cbdbA281	1.919e-119	392.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,34CIZ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158338_k127_3551760_3	479434.Sthe_1996	2.885e-107	368.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,27Y3G@189775|Thermomicrobia	189775|Thermomicrobia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158338_k127_3551760_2	1521187.JPIM01000054_gene3099	6.903e-114	383.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,374X6@32061|Chloroflexia	32061|Chloroflexia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158338_k127_3551760_6	1382356.JQMP01000004_gene471	2.089e-87	299.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158338_k127_3551760_4	926569.ANT_23360	8.783e-102	350.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158338_k127_3551760_7	370438.PTH_1862	1.691e-85	299.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158338_k127_3551760_8	324602.Caur_0755	2.567e-77	273.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi,374ZS@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158338_k127_3551760_9	1196323.ALKF01000189_gene1157	2.899e-64	231.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,26QRK@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158338_k127_3559568_0	222534.KB893711_gene5041	3.445e-60	224.0	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4ESEF@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158338_k127_3574342_8	1278307.KB907016_gene3433	6.023e-09	57.0	COG2267@1|root,COG2267@2|Bacteria,1R299@1224|Proteobacteria,1T5JY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_3574342_0	487521.OCU_02310	2.024e-125	423.0	COG1960@1|root,COG1960@2|Bacteria,2IAIE@201174|Actinobacteria,237ZZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE35	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158338_k127_3574342_4	395494.Galf_0064	8.492e-49	191.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,44VE1@713636|Nitrosomonadales	28216|Betaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158338_k127_3574342_6	1382306.JNIM01000001_gene3980	1.242e-35	147.0	COG1184@1|root,COG1184@2|Bacteria,2G9CC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the eIF-2B alpha beta delta subunits family	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
SRR25158338_k127_3574342_1	243231.GSU1431	5.182e-118	399.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,43U4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
SRR25158338_k127_3574342_7	644966.Tmar_1028	2.748e-28	124.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WD66@538999|Clostridiales incertae sedis	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158338_k127_3574342_3	1382306.JNIM01000001_gene3602	9.401e-53	195.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SRR25158338_k127_3574342_5	255470.cbdbA940	4.468e-36	151.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi,34D5W@301297|Dehalococcoidia	301297|Dehalococcoidia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158338_k127_3574342_2	552811.Dehly_0527	1.665e-93	319.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,34CIQ@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158338_k127_3626583_14	565033.GACE_1099	8.244e-13	69.0	COG0498@1|root,arCOG01434@2157|Archaea,2XTNY@28890|Euryarchaeota,245TE@183980|Archaeoglobi	183980|Archaeoglobi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_3626583_1	1173020.Cha6605_2826	6.023e-159	510.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_3626583_17	1521187.JPIM01000056_gene2613	4.435e-11	67.0	COG1497@1|root,COG1497@2|Bacteria	2|Bacteria	K	Regulatory protein Crp	-	-	-	ko:K07730	-	-	-	-	ko00000,ko03000	-	-	-	HTH_24,MarR_2
SRR25158338_k127_3626583_16	1283283.ATXA01000006_gene1745	1.201e-11	67.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4ETIA@85013|Frankiales	201174|Actinobacteria	O	PFAM Glutaredoxin 2	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158338_k127_3626583_8	525904.Tter_1732	2.017e-39	158.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158338_k127_3626583_9	1089455.MOPEL_074_00830	1.276e-37	162.0	COG1333@1|root,COG1333@2|Bacteria,2I0CQ@201174|Actinobacteria,4F61R@85018|Dermatophilaceae	201174|Actinobacteria	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
SRR25158338_k127_3626583_11	1444309.JAQG01000100_gene4742	4.624e-36	147.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,274A1@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158338_k127_3626583_7	555088.DealDRAFT_1127	1.668e-39	161.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158338_k127_3626583_18	96561.Dole_1877	3.058e-07	61.0	COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria,2MP4U@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
SRR25158338_k127_3626583_3	1382306.JNIM01000001_gene1286	5.658e-73	256.0	COG3442@1|root,COG3442@2|Bacteria,2G6KU@200795|Chloroflexi	200795|Chloroflexi	H	PFAM CobB CobQ domain protein glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158338_k127_3626583_2	765420.OSCT_0823	1.675e-109	381.0	COG0769@1|root,COG0769@2|Bacteria,2G81F@200795|Chloroflexi,3757I@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Mur ligase, middle domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158338_k127_3626583_6	1123226.KB899296_gene403	1.582e-40	166.0	COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,26RQQ@186822|Paenibacillaceae	91061|Bacilli	S	acetyltransferase involved in intracellular survival and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158338_k127_3626583_4	981369.JQMJ01000003_gene7777	9.638e-44	170.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,2NHK8@228398|Streptacidiphilus	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158338_k127_3626583_5	1380370.JIBA01000015_gene102	6.391e-42	160.0	COG0406@1|root,COG0406@2|Bacteria,2IJ7S@201174|Actinobacteria,4FGNR@85021|Intrasporangiaceae	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158338_k127_3626583_15	196162.Noca_2922	7.603e-12	71.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54	ko:K01533,ko:K01534,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5,3.A.3.6	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158338_k127_3626583_0	552811.Dehly_1206	0.0	1020.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,34CJR@301297|Dehalococcoidia	301297|Dehalococcoidia	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158338_k127_3626583_10	105559.Nwat_2925	1.277e-37	151.0	COG0500@1|root,COG2226@2|Bacteria,1RB5H@1224|Proteobacteria,1SYTI@1236|Gammaproteobacteria,1X2IR@135613|Chromatiales	135613|Chromatiales	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.103	ko:K05929	ko00564,map00564	-	R02037,R06868,R06869	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25
SRR25158338_k127_3626583_12	485913.Krac_8885	2.052e-31	126.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158338_k127_3626583_13	869210.Marky_1752	3.072e-18	87.0	COG3055@1|root,COG3055@2|Bacteria,1WK3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
SRR25158338_k127_367631_21	1280671.AUJH01000020_gene3780	3.408e-18	93.0	COG1011@1|root,COG1011@2|Bacteria,1UPBD@1239|Firmicutes,2545N@186801|Clostridia,4BYDB@830|Butyrivibrio	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158338_k127_367631_1	479434.Sthe_1801	4.279e-160	515.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158338_k127_367631_4	311424.DhcVS_1009	2.518e-136	445.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158338_k127_367631_13	1297569.MESS2_1000038	9.71e-51	190.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
SRR25158338_k127_367631_0	314287.GB2207_00530	9.084e-175	552.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria,1J9DR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158338_k127_367631_16	882086.SacxiDRAFT_0856	1.118e-38	149.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria,4E51C@85010|Pseudonocardiales	201174|Actinobacteria	P	TIGRFAM deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158338_k127_367631_3	1121930.AQXG01000006_gene797	2.172e-154	507.0	COG0025@1|root,COG0025@2|Bacteria,4PKJ5@976|Bacteroidetes	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158338_k127_367631_12	264732.Moth_0070	2.562e-56	204.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_367631_18	246197.MXAN_5990	2.824e-37	158.0	COG0642@1|root,COG2205@2|Bacteria	246197.MXAN_5990|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_367631_10	926550.CLDAP_21330	1.646e-70	254.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158338_k127_367631_11	1173020.Cha6605_5319	9.184e-61	222.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158338_k127_367631_22	1120971.AUCA01000019_gene1128	5.404e-18	90.0	COG0346@1|root,COG2185@1|root,COG0346@2|Bacteria,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4IRRS@91061|Bacilli,2794J@186823|Alicyclobacillaceae	91061|Bacilli	EI	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,Glyoxalase_4
SRR25158338_k127_367631_19	211165.AJLN01000055_gene4563	1.495e-19	93.0	COG4113@1|root,COG4113@2|Bacteria,1G8AN@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158338_k127_367631_15	1101188.KI912156_gene4129	4.844e-40	162.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158338_k127_367631_8	1121468.AUBR01000028_gene1521	3.542e-86	295.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158338_k127_367631_6	880073.Calab_0629	6.23e-130	425.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158338_k127_367631_23	1211815.CBYP010000051_gene670	5.975e-06	57.0	2BIU5@1|root,32D21@2|Bacteria,2HWTA@201174|Actinobacteria,4EW7A@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_367631_24	926560.KE387027_gene262	0.0003949	52.0	2F64E@1|root,33YNP@2|Bacteria	2|Bacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,MDMPI_N
SRR25158338_k127_367631_7	1121104.AQXH01000001_gene1475	1.542e-117	387.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
SRR25158338_k127_367631_14	330214.NIDE3836	6.331e-43	165.0	COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	prhJ	-	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158338_k127_367631_9	479434.Sthe_0152	9.651e-79	274.0	COG2132@1|root,COG2132@2|Bacteria,2G8IH@200795|Chloroflexi,27YH6@189775|Thermomicrobia	189775|Thermomicrobia	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
SRR25158338_k127_367631_17	292459.STH3142	1.708e-38	149.0	COG4231@1|root,COG4231@2|Bacteria,1VIY6@1239|Firmicutes,24PDQ@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158338_k127_367631_20	1501230.ET33_34005	8.479e-19	89.0	COG3708@1|root,COG3708@2|Bacteria,1VFMZ@1239|Firmicutes,4HQ9U@91061|Bacilli,275ZD@186822|Paenibacillaceae	91061|Bacilli	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
SRR25158338_k127_367631_2	479434.Sthe_0722	4.847e-160	529.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2G7EM@200795|Chloroflexi,27Z3D@189775|Thermomicrobia	189775|Thermomicrobia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158338_k127_367631_5	289376.THEYE_A0572	9.146e-136	450.0	COG0474@1|root,COG0474@2|Bacteria,3J0YX@40117|Nitrospirae	40117|Nitrospirae	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158338_k127_3701008_7	1210884.HG799462_gene8483	6.439e-08	56.0	COG0517@1|root,COG0517@2|Bacteria,2J0MQ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158338_k127_3701008_4	420324.KI911965_gene1160	7.031e-66	235.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,1JQT1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	TIGRFAM acyl-CoA thioesterase II	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158338_k127_3701008_2	357808.RoseRS_3818	1.442e-78	269.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_3701008_3	525904.Tter_2868	2.143e-78	280.0	COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158338_k127_3701008_5	101510.RHA1_ro11164	1.003e-39	161.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4G00D@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_3701008_6	1049564.TevJSym_aa00380	9.133e-32	131.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria,1J66R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158338_k127_3701008_1	479434.Sthe_2452	2.142e-86	302.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158338_k127_3701008_0	485913.Krac_11995	2.662e-102	339.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158338_k127_3758075_9	1205680.CAKO01000038_gene1665	1.638e-09	65.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158338_k127_3758075_4	930169.B5T_03304	9.671e-69	248.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XJ29@135619|Oceanospirillales	135619|Oceanospirillales	P	transporter, permease	oppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158338_k127_3758075_5	1411123.JQNH01000001_gene883	6.006e-62	226.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2TRX5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158338_k127_3758075_8	55952.BU52_16220	4.853e-22	102.0	COG3631@1|root,COG3631@2|Bacteria,2IFBE@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158338_k127_3758075_0	479434.Sthe_1873	2.398e-182	577.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi,27XJP@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_3758075_7	479432.Sros_9203	4.731e-43	177.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria,4ENND@85012|Streptosporangiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158338_k127_3758075_6	383372.Rcas_4413	9.121e-49	182.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi,375IK@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158338_k127_3758075_3	338963.Pcar_0733	4.933e-69	243.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
SRR25158338_k127_3758075_1	1128421.JAGA01000002_gene245	1.579e-110	376.0	COG0547@1|root,COG0547@2|Bacteria,2NNVH@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0004048,GO:0004049,GO:0004425,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495,iJN746.PP_0421,iSBO_1134.SBO_1803,iSbBS512_1146.SbBS512_E1488,iYL1228.KPN_01256	GATase,Glycos_trans_3N,Glycos_transf_3
SRR25158338_k127_3758075_2	479434.Sthe_1877	2.701e-82	278.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158338_k127_3758075_10	1120948.KB903244_gene3135	0.0005693	43.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4E0HI@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K18009	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_3861070_0	357808.RoseRS_1979	1.936e-172	553.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158338_k127_3861070_1	765420.OSCT_1472	4.206e-108	370.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,376RY@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158338_k127_3861070_2	1519464.HY22_02230	3.093e-66	237.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158338_k127_3861070_3	1116369.KB890025_gene5099	1.404e-44	181.0	COG1173@1|root,COG1173@2|Bacteria,1R49K@1224|Proteobacteria,2TUY6@28211|Alphaproteobacteria,43P66@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158338_k127_3861070_4	292459.STH1444	0.0007807	45.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_3924273_4	255470.cbdbA808	5.874e-161	516.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi,34CY8@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158338_k127_3924273_6	795359.TOPB45_0663	1.471e-144	466.0	COG0059@1|root,COG0059@2|Bacteria,2GH4M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158338_k127_3924273_12	243164.DET0832	3.33e-52	190.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi,34D5M@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
SRR25158338_k127_3924273_3	552811.Dehly_0666	7.318e-214	679.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158338_k127_3924273_2	414684.RC1_1163	2.893e-216	685.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,2JPT6@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158338_k127_3924273_18	536019.Mesop_3627	1.201e-07	61.0	COG0454@1|root,COG0456@2|Bacteria,1RBE6@1224|Proteobacteria,2U9H8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ttr	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158338_k127_3924273_10	1232683.ADIMK_0558	9.002e-73	258.0	COG2334@1|root,COG2334@2|Bacteria,1PGM7@1224|Proteobacteria,1RNPA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	homoserine kinase type II (Protein kinase fold)	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158338_k127_3924273_5	425104.Ssed_2247	2.832e-149	483.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,1RMRF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R01155,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
SRR25158338_k127_3924273_15	266117.Rxyl_2570	1.655e-29	130.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158338_k127_3924273_11	1125863.JAFN01000001_gene82	5.938e-69	249.0	COG0500@1|root,COG0644@1|root,COG0644@2|Bacteria,COG2226@2|Bacteria,1MXQY@1224|Proteobacteria,42UR3@68525|delta/epsilon subdivisions,2WQQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158338_k127_3924273_17	1128421.JAGA01000001_gene2189	1.931e-10	73.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,SLH
SRR25158338_k127_3924273_16	357808.RoseRS_3398	3.237e-12	78.0	2EQGV@1|root,33I2V@2|Bacteria,2G7HG@200795|Chloroflexi,375SC@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
SRR25158338_k127_3924273_8	255470.cbdbA11	1.969e-112	379.0	COG0115@1|root,COG0115@2|Bacteria,2G5PM@200795|Chloroflexi,34CQR@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158338_k127_3924273_14	552811.Dehly_0214	2.307e-41	164.0	2A4BY@1|root,30SXK@2|Bacteria,2GASQ@200795|Chloroflexi,34D9B@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3924273_1	525904.Tter_0811	1.924e-308	972.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158338_k127_3924273_7	552811.Dehly_1132	4.641e-116	389.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,34CYP@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158338_k127_3924273_9	1207063.P24_14749	3.092e-99	336.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2JPEG@204441|Rhodospirillales	204441|Rhodospirillales	FL	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158338_k127_3924273_13	309801.trd_A0437	7.99e-50	190.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi,27Z2V@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158338_k127_3924273_0	867845.KI911784_gene948	0.0	1415.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi,374ZB@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158338_k127_3948406_11	479434.Sthe_0151	1.495e-36	147.0	COG1853@1|root,COG1853@2|Bacteria,2G9RE@200795|Chloroflexi,27Y9A@189775|Thermomicrobia	189775|Thermomicrobia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158338_k127_3948406_16	1265310.CCBD010000045_gene821	3.952e-27	122.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,23BEX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158338_k127_3948406_17	557599.MKAN_03995	1.87e-24	108.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM,DUF3225,DUF4440,SnoaL_2,SnoaL_3
SRR25158338_k127_3948406_1	1206732.BAGD01000054_gene1961	1.862e-97	332.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_3948406_18	350058.Mvan_0859	2.541e-20	102.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,239DM@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158338_k127_3948406_3	1206732.BAGD01000054_gene1961	7.798e-94	321.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FWX1@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_3948406_0	1454004.AW11_01670	2.197e-185	588.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2W1P8@28216|Betaproteobacteria	28216|Betaproteobacteria	CT	Domain in cystathionine beta-synthase and other proteins.	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,CBS
SRR25158338_k127_3948406_5	1123322.KB904656_gene689	1.033e-86	294.0	COG0500@1|root,COG0500@2|Bacteria,2I5J7@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158338_k127_3948406_14	1121428.DESHY_60285___1	9.135e-33	135.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158338_k127_3948406_8	552811.Dehly_1588	4.603e-50	192.0	COG2159@1|root,COG2159@2|Bacteria,2G6CW@200795|Chloroflexi,34CYX@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158338_k127_3948406_4	1449126.JQKL01000003_gene1757	8.987e-91	308.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,267Z6@186813|unclassified Clostridiales	186801|Clostridia	G	Dehydrogenase E1 component	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158338_k127_3948406_6	760568.Desku_3320	1.359e-86	296.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158338_k127_3948406_7	1121468.AUBR01000027_gene2887	1.462e-51	194.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,42EQ0@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158338_k127_3948406_15	156889.Mmc1_3012	2.501e-32	139.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2TWS0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase	MA20_23160	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158338_k127_3948406_9	1242864.D187_009928	1.307e-43	175.0	COG3437@1|root,COG3437@2|Bacteria,1RGGM@1224|Proteobacteria,42RTT@68525|delta/epsilon subdivisions,2WNA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
SRR25158338_k127_3948406_13	479434.Sthe_0480	2.147e-34	143.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XV7@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158338_k127_3948406_10	1499967.BAYZ01000041_gene2356	4.408e-43	174.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158338_k127_3948406_12	390989.JOEG01000011_gene200	5.102e-35	138.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria,4DDQ3@85008|Micromonosporales	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158338_k127_3948406_2	1329516.JPST01000003_gene1133	6.055e-96	321.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,27AWR@186824|Thermoactinomycetaceae	91061|Bacilli	O	Found in ATP-dependent protease La (LON)	lon	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158338_k127_3962137_16	1282876.BAOK01000001_gene3189	1.393e-45	181.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,4BP67@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	MA20_04655	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_3962137_3	1231057.AMGD01000021_gene3108	2.919e-130	441.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,26EJ1@186818|Planococcaceae	91061|Bacilli	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	bfmBC	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158338_k127_3962137_7	986075.CathTA2_1040	1.17e-109	364.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli	91061|Bacilli	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
SRR25158338_k127_3962137_2	326427.Cagg_2096	1.512e-131	428.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158338_k127_3962137_6	1120971.AUCA01000019_gene1132	7.805e-110	367.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,27892@186823|Alicyclobacillaceae	91061|Bacilli	C	e3 binding domain	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158338_k127_3962137_15	1033732.CAHI01000034_gene2466	3.103e-46	184.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,2FMSJ@200643|Bacteroidia,22UCA@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158338_k127_3962137_8	479434.Sthe_1775	2.063e-93	313.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158338_k127_3962137_0	479434.Sthe_1776	4.014e-189	632.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158338_k127_3962137_4	47839.CCAU010000002_gene2724	5.586e-127	419.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,235AT@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_3962137_10	311424.DhcVS_930	9.126e-72	253.0	COG1173@1|root,COG1173@2|Bacteria,2G9WH@200795|Chloroflexi,34DKE@301297|Dehalococcoidia	301297|Dehalococcoidia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158338_k127_3962137_9	255470.cbdbA1038	3.898e-93	316.0	COG0601@1|root,COG0601@2|Bacteria,2G9WT@200795|Chloroflexi,34DMG@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158338_k127_3962137_11	1382356.JQMP01000003_gene2464	4.046e-68	253.0	COG4166@1|root,COG4166@2|Bacteria,2GBUU@200795|Chloroflexi,27YZK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158338_k127_3962137_14	1120936.KB907208_gene1207	2.471e-50	198.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_3962137_5	1123389.ATXJ01000004_gene1143	5.083e-111	370.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158338_k127_3962137_18	272123.Anacy_3546	2.428e-12	78.0	COG0857@1|root,COG0857@2|Bacteria,1G0QB@1117|Cyanobacteria,1HIX5@1161|Nostocales	1117|Cyanobacteria	C	PFAM DRTGG domain	pta	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
SRR25158338_k127_3962137_17	309801.trd_0198	1.271e-33	137.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi,27Y98@189775|Thermomicrobia	189775|Thermomicrobia	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158338_k127_3962137_1	525904.Tter_2704	8.923e-139	454.0	COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158338_k127_3962137_13	479434.Sthe_2681	2.545e-55	205.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi,27YA3@189775|Thermomicrobia	189775|Thermomicrobia	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158338_k127_3962137_12	1396141.BATP01000032_gene4427	2e-57	210.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158338_k127_4064509_0	1121403.AUCV01000041_gene158	4.588e-168	545.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.2,1.6.5.3	ko:K00124,ko:K00335,ko:K00355,ko:K18331	ko00130,ko00190,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,ko05200,ko05225,ko05418,map00130,map00190,map00630,map00680,map01100,map01110,map01120,map01200,map05200,map05225,map05418	M00144	R00519,R02964,R03643,R03816,R11945	RC00061,RC00819,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRR25158338_k127_4064509_2	1033991.RLEG12_29635	3.027e-22	103.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,2U72T@28211|Alphaproteobacteria,4BBHA@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NADH ubiquinone oxidoreductase 24 kD subunit	fdsG	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx
SRR25158338_k127_4064509_3	472175.EL18_00518	2.167e-17	93.0	COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158338_k127_4064509_4	485913.Krac_12253	9.257e-16	81.0	29684@1|root,2ZTI4@2|Bacteria,2G9NR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_4064509_1	1347369.CCAD010000086_gene1755	1.535e-62	217.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,1ZE5H@1386|Bacillus	91061|Bacilli	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_4095293_0	1191523.MROS_2763	1.146e-137	466.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158338_k127_4095293_2	525904.Tter_2416	5.992e-100	336.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158338_k127_4095293_1	767817.Desgi_0495	8.251e-111	377.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,262AS@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158338_k127_4095293_7	641491.DND132_0694	2.109e-12	74.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	pcmE	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158338_k127_4095293_8	641491.DND132_0694	8.955e-06	55.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	pcmE	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158338_k127_4095293_4	401526.TcarDRAFT_1841	3.008e-48	182.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4H217@909932|Negativicutes	909932|Negativicutes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158338_k127_4095293_5	1121918.ARWE01000001_gene1418	4.111e-47	179.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,43T99@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158338_k127_4095293_3	1348657.M622_02725	1.118e-66	241.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_4095293_6	331869.BAL199_15313	4.452e-14	84.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,4BPJW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158338_k127_4103433_4	485913.Krac_12092	2.12e-25	106.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158338_k127_4103433_2	755731.Clo1100_2057	3.426e-180	579.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,36UI3@31979|Clostridiaceae	186801|Clostridia	C	carboxyltransferase	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
SRR25158338_k127_4103433_6	396588.Tgr7_1916	3.817e-13	80.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales	135613|Chromatiales	CI	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158338_k127_4103433_3	1276756.AUEX01000033_gene2	2.64e-80	275.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2W1BR@28216|Betaproteobacteria,4AH9B@80864|Comamonadaceae	28216|Betaproteobacteria	H	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158338_k127_4103433_0	555088.DealDRAFT_1177	7.469e-217	692.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,42KC8@68298|Syntrophomonadaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158338_k127_4103433_5	1111069.TCCBUS3UF1_10730	1.147e-22	101.0	COG3870@1|root,COG3870@2|Bacteria,1WK0D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG3870 conserved	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
SRR25158338_k127_4103433_1	552811.Dehly_0772	1.933e-183	584.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,34D2R@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158338_k127_4103433_7	675635.Psed_3911	5.85e-06	58.0	COG0454@1|root,COG0456@2|Bacteria,2IPMN@201174|Actinobacteria,4E7UE@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_4104812_3	1265310.CCBD010000005_gene2690	1.078e-22	102.0	COG5015@1|root,COG5015@2|Bacteria,2GPHG@201174|Actinobacteria,239IH@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158338_k127_4104812_0	439235.Dalk_3873	8.741e-133	436.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42QX5@68525|delta/epsilon subdivisions,2WMXW@28221|Deltaproteobacteria,2MJHC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158338_k127_4104812_4	1395587.P364_0109490	3.633e-20	98.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26XRF@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158338_k127_4104812_2	243231.GSU1322	3.381e-38	153.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
SRR25158338_k127_4104812_1	622637.KE124774_gene3956	2.212e-46	175.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,36X9F@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1,6.2.1.16	ko:K01895,ko:K01907	ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354,R01357	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158338_k127_4165500_0	1123288.SOV_4c07550	2.964e-133	440.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4H3I7@909932|Negativicutes	909932|Negativicutes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158338_k127_4165500_9	1121377.KB906399_gene1660	2.783e-06	56.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158338_k127_4165500_8	519442.Huta_1637	2.262e-13	76.0	arCOG14964@1|root,arCOG14964@2157|Archaea,2Y0J8@28890|Euryarchaeota,23XF5@183963|Halobacteria	183963|Halobacteria	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
SRR25158338_k127_4165500_5	1382306.JNIM01000001_gene1708	5.329e-46	176.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_25
SRR25158338_k127_4165500_1	1382306.JNIM01000001_gene4091	4.475e-115	383.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158338_k127_4165500_4	1122221.JHVI01000010_gene2527	2.181e-88	299.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158338_k127_4165500_2	311424.DhcVS_1	8.008e-113	380.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,34CS8@301297|Dehalococcoidia	301297|Dehalococcoidia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158338_k127_4165500_3	552811.Dehly_1339	5.791e-103	349.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi,34CK2@301297|Dehalococcoidia	301297|Dehalococcoidia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158338_k127_4165500_6	552811.Dehly_1340	9.264e-42	166.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,34D3W@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158338_k127_4165500_7	883126.HMPREF9710_00286	7.947e-14	79.0	COG4122@1|root,COG4122@2|Bacteria,1N57D@1224|Proteobacteria,2WBFQ@28216|Betaproteobacteria,477DF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158338_k127_416956_0	1283299.AUKG01000003_gene204	3.024e-156	503.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158338_k127_416956_4	309801.trd_1490	9.752e-24	108.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158338_k127_416956_2	1120973.AQXL01000131_gene2103	3.923e-93	318.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,2783K@186823|Alicyclobacillaceae	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158338_k127_416956_5	1120973.AQXL01000129_gene2456	1.333e-08	61.0	COG0745@1|root,COG0745@2|Bacteria	1120973.AQXL01000129_gene2456|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_416956_1	926550.CLDAP_20060	3.197e-148	512.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158338_k127_416956_3	243164.DET1025	6.568e-56	205.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi,34D6R@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158338_k127_4196012_11	243230.DR_2242	4.49e-19	94.0	COG0450@1|root,COG0450@2|Bacteria,1WJFK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158338_k127_4196012_3	344747.PM8797T_17317	1.069e-60	220.0	COG1319@1|root,COG1319@2|Bacteria,2IYV7@203682|Planctomycetes	203682|Planctomycetes	C	COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158338_k127_4196012_4	485913.Krac_2433	8.656e-55	202.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158338_k127_4196012_0	1382356.JQMP01000001_gene704	5.666e-223	716.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158338_k127_4196012_12	400682.PAC_15717719	1.65e-08	65.0	COG1028@1|root,KOG4170@1|root,KOG0725@2759|Eukaryota,KOG4170@2759|Eukaryota,38DZE@33154|Opisthokonta,3BA0D@33208|Metazoa	33208|Metazoa	Q	Hydroxysteroid dehydrogenase-like protein	HSDL2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	SCP2,adh_short
SRR25158338_k127_4196012_1	479434.Sthe_1647	1.06e-151	493.0	COG0277@1|root,COG0277@2|Bacteria,2GA3E@200795|Chloroflexi,27Z04@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158338_k127_4196012_7	1121090.KB894685_gene3544	1.907e-35	142.0	COG2068@1|root,COG2068@2|Bacteria,1UY6E@1239|Firmicutes,4IK8C@91061|Bacilli,1ZFU5@1386|Bacillus	91061|Bacilli	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158338_k127_4196012_9	1333998.M2A_0668	1.616e-20	97.0	COG1545@1|root,COG1545@2|Bacteria,1RFF1@1224|Proteobacteria,2UTI3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158338_k127_4196012_2	1333998.M2A_0667	2.068e-139	452.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,4BP5Q@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158338_k127_4196012_8	316055.RPE_0722	1.234e-31	134.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria,3JTWA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158338_k127_4196012_5	2074.JNYD01000008_gene1214	1.234e-53	201.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4DXPW@85010|Pseudonocardiales	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158338_k127_4196012_6	1120972.AUMH01000015_gene1287	2.012e-38	148.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,279WU@186823|Alicyclobacillaceae	91061|Bacilli	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158338_k127_4196012_10	1444309.JAQG01000011_gene2207	2.048e-19	88.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,26RKR@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158338_k127_4269916_12	926569.ANT_08650	9.579e-54	194.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
SRR25158338_k127_4269916_1	311424.DhcVS_50	1.991e-253	816.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,34CVN@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158338_k127_4269916_19	237368.SCABRO_01685	9.727e-20	93.0	COG0816@1|root,COG0816@2|Bacteria,2J0EV@203682|Planctomycetes	203682|Planctomycetes	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158338_k127_4269916_9	479434.Sthe_3265	9.472e-66	239.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi,27XHU@189775|Thermomicrobia	189775|Thermomicrobia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158338_k127_4269916_15	58344.JOEL01000011_gene3702	2.203e-34	138.0	COG0662@1|root,COG0662@2|Bacteria,2IHU8@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158338_k127_4269916_10	1382306.JNIM01000001_gene3651	1.974e-62	225.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158338_k127_4269916_4	671143.DAMO_1404	1.191e-130	428.0	COG0082@1|root,COG0082@2|Bacteria,2NNQ8@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976,iNJ661.Rv2540c	Chorismate_synt
SRR25158338_k127_4269916_14	926560.KE387023_gene1429	2.196e-44	167.0	COG0454@1|root,COG0454@2|Bacteria,1WMQ1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SRR25158338_k127_4269916_5	1382306.JNIM01000001_gene1342	5.129e-113	387.0	COG0337@1|root,COG0337@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158338_k127_4269916_18	1382306.JNIM01000001_gene968	1.213e-23	102.0	COG1254@1|root,COG1254@2|Bacteria,2G728@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158338_k127_4269916_3	1340493.JNIF01000003_gene3441	5.422e-143	477.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,3Y3U8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158338_k127_4269916_16	479434.Sthe_3506	4.571e-32	136.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2G7EW@200795|Chloroflexi	200795|Chloroflexi	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR25158338_k127_4269916_6	234267.Acid_1785	3.019e-90	321.0	COG1020@1|root,COG1020@2|Bacteria,3Y61Y@57723|Acidobacteria	57723|Acidobacteria	H	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158338_k127_4269916_8	562970.Btus_2586	2.26e-71	247.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,4HTP0@91061|Bacilli,279M4@186823|Alicyclobacillaceae	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158338_k127_4269916_7	1122611.KB903974_gene2885	1.151e-71	251.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158338_k127_4269916_0	1123073.KB899242_gene946	1.294e-260	831.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria,1X3QM@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA ligase	lig3	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158338_k127_4269916_13	234267.Acid_7844	1.437e-52	199.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,3Y2VV@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase LigD, ligase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158338_k127_4269916_20	882083.SacmaDRAFT_3028	6.915e-09	62.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria,4ECQ0@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
SRR25158338_k127_4269916_2	357808.RoseRS_3807	1.197e-162	524.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,374XY@32061|Chloroflexia	32061|Chloroflexia	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158338_k127_4269916_17	448385.sce1048	2.217e-28	119.0	COG0454@1|root,COG0456@2|Bacteria,1RH0C@1224|Proteobacteria,433BT@68525|delta/epsilon subdivisions,2X7UC@28221|Deltaproteobacteria,2YVJS@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_4269916_11	234267.Acid_1785	2.777e-56	209.0	COG1020@1|root,COG1020@2|Bacteria,3Y61Y@57723|Acidobacteria	57723|Acidobacteria	H	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158338_k127_4271620_14	378806.STAUR_3856	1.933e-18	87.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158338_k127_4271620_13	926569.ANT_15290	6.761e-20	97.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_4271620_18	526225.Gobs_1057	0.0008048	52.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4ERIN@85013|Frankiales	201174|Actinobacteria	E	PFAM Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158338_k127_4271620_10	309801.trd_0814	2.441e-37	146.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi,27YDS@189775|Thermomicrobia	189775|Thermomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158338_k127_4271620_7	710685.MycrhN_2757	5.019e-65	242.0	COG0789@1|root,COG2114@1|root,COG0789@2|Bacteria,COG2114@2|Bacteria,2ICT6@201174|Actinobacteria,23F0X@1762|Mycobacteriaceae	201174|Actinobacteria	KT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc,MerR_1,YHS
SRR25158338_k127_4271620_2	552811.Dehly_0249	1.044e-109	374.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,34D4S@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158338_k127_4271620_17	1306174.JODP01000001_gene4897	1.219e-05	57.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria	201174|Actinobacteria	K	domain protein	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158338_k127_4271620_0	765420.OSCT_2657	2.548e-134	448.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi,374UZ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM phosphoesterase, RecJ domain protein	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158338_k127_4271620_11	1996.JOFO01000075_gene4347	6.567e-22	100.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4EK3X@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158338_k127_4271620_8	1038866.KB902768_gene4907	3.559e-43	169.0	COG2267@1|root,COG2267@2|Bacteria,1N8UK@1224|Proteobacteria,2U35V@28211|Alphaproteobacteria,3JX10@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158338_k127_4271620_9	552811.Dehly_0557	2.924e-42	171.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SRR25158338_k127_4271620_1	479434.Sthe_0720	7.562e-121	397.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,27XS7@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158338_k127_4271620_6	1122182.KB903834_gene6100	5.93e-68	239.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria,4DCRD@85008|Micromonosporales	201174|Actinobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158338_k127_4271620_4	1333998.M2A_2110	1.784e-89	307.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158338_k127_4271620_15	479434.Sthe_2183	5.404e-18	90.0	COG1547@1|root,COG1547@2|Bacteria,2GAFU@200795|Chloroflexi,27YQW@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158338_k127_4271620_5	1280949.HAD_16522	5.801e-68	242.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2U31Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_40045	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158338_k127_4271620_3	1155718.KB891855_gene122	2.625e-106	352.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria	201174|Actinobacteria	Q	beta-lactamase domain protein	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
SRR25158338_k127_4271620_16	1197130.BAFM01000004_gene992	2.591e-10	73.0	COG1514@1|root,arCOG01736@2157|Archaea,2Y0VA@28890|Euryarchaeota,23Y3H@183963|Halobacteria	183963|Halobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158338_k127_4271620_12	933262.AXAM01000004_gene2383	1.25e-20	96.0	COG0613@1|root,COG0613@2|Bacteria,1NFVB@1224|Proteobacteria,43BBY@68525|delta/epsilon subdivisions,2X6R1@28221|Deltaproteobacteria,2MPIB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	APH,DUF2889,PHP_C
SRR25158338_k127_4304639_0	1382306.JNIM01000001_gene1358	1.1e-152	504.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158338_k127_4304639_1	1128421.JAGA01000002_gene1728	1.797e-91	314.0	COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158338_k127_4354797_5	243232.MJ_0682	5.997e-13	70.0	COG1372@1|root,COG1690@1|root,arCOG03158@2157|Archaea,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,23Q3C@183939|Methanococci	183939|Methanococci	L	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
SRR25158338_k127_4354797_2	552811.Dehly_1536	4.889e-73	258.0	COG0668@1|root,COG0668@2|Bacteria,2G75W@200795|Chloroflexi,34D81@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158338_k127_4354797_3	1123023.JIAI01000002_gene4668	1.143e-56	203.0	COG0500@1|root,COG2226@2|Bacteria,2IHXS@201174|Actinobacteria,4E44I@85010|Pseudonocardiales	201174|Actinobacteria	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158338_k127_4354797_1	953739.SVEN_0524	4.167e-110	371.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158338_k127_4354797_4	211114.JOEF01000023_gene5769	1.781e-24	107.0	COG0454@1|root,COG0456@2|Bacteria,2IRE7@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158338_k127_4354797_0	255470.cbdbA1111	1.541e-217	696.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158338_k127_4371311_2	1117379.BABA_14322	1.215e-88	303.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_4371311_0	309801.trd_0738	0.0	1107.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,27XEX@189775|Thermomicrobia	189775|Thermomicrobia	L	Bacterial DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158338_k127_4371311_6	596151.DesfrDRAFT_0332	2.023e-29	123.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,2MCUY@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158338_k127_4371311_5	869210.Marky_2009	9.449e-46	182.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1WJ1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR25158338_k127_4371311_4	1157490.EL26_07705	3.595e-46	176.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,278FE@186823|Alicyclobacillaceae	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158338_k127_4371311_3	767817.Desgi_1330	2.766e-56	208.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,260D2@186807|Peptococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158338_k127_4371311_1	696281.Desru_1138	1.226e-124	411.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158338_k127_4371311_7	1120959.ATXF01000005_gene891	4.039e-25	109.0	COG1695@1|root,COG1695@2|Bacteria,2H1J3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158338_k127_4425594_1	395961.Cyan7425_3807	7.52e-100	337.0	COG0391@1|root,COG0391@2|Bacteria,1G0R0@1117|Cyanobacteria,3KH52@43988|Cyanothece	1117|Cyanobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158338_k127_4425594_7	525904.Tter_0916	1.043e-06	57.0	COG1314@1|root,COG1314@2|Bacteria,2NS1U@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158338_k127_4425594_3	926550.CLDAP_38550	3.296e-97	339.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158338_k127_4425594_4	867845.KI911784_gene22	1.167e-73	265.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,3759R@32061|Chloroflexia	32061|Chloroflexia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158338_k127_4425594_5	1382306.JNIM01000001_gene3871	5.681e-35	142.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158338_k127_4425594_2	986075.CathTA2_1446	9.984e-99	335.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli	91061|Bacilli	C	carnitine dehydratase	amacr	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158338_k127_4425594_6	1121272.KB903292_gene3732	3.886e-30	125.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria,4DDK5@85008|Micromonosporales	201174|Actinobacteria	S	MgtC family	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158338_k127_4425594_0	311424.DhcVS_182	0.0	1065.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,34CK0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	leucyl-tRNA aminoacylation	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158338_k127_4443470_5	1380390.JIAT01000009_gene1363	1.47e-90	316.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,4CU4I@84995|Rubrobacteria	84995|Rubrobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158338_k127_4443470_8	479434.Sthe_1347	9.437e-84	296.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158338_k127_4443470_19	1128421.JAGA01000001_gene2440	3.712e-33	139.0	COG2265@1|root,COG2265@2|Bacteria,2NRDB@2323|unclassified Bacteria	2|Bacteria	J	Methyltransferase domain	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31
SRR25158338_k127_4443470_24	926569.ANT_19700	1.998e-09	67.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158338_k127_4443470_22	1128421.JAGA01000003_gene3020	2.627e-13	79.0	COG1238@1|root,COG1238@2|Bacteria	2|Bacteria	I	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158338_k127_4443470_16	926550.CLDAP_14080	1.647e-43	168.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_14080|-	T	phosphorelay signal transduction system	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
SRR25158338_k127_4443470_1	1382356.JQMP01000003_gene2542	1.167e-126	420.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,27XRP@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158338_k127_4443470_12	479434.Sthe_1142	1.033e-54	199.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158338_k127_4443470_7	525904.Tter_2814	3.615e-84	304.0	COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158338_k127_4443470_0	525904.Tter_2810	2.514e-128	424.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158338_k127_4443470_6	5127.CCT67725	5.539e-89	304.0	COG1087@1|root,KOG1371@2759|Eukaryota,39KCQ@33154|Opisthokonta,3PBHS@4751|Fungi,3RN10@4890|Ascomycota,21D2X@147550|Sordariomycetes,3TKEP@5125|Hypocreales,1FVEQ@110618|Nectriaceae	4751|Fungi	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SRR25158338_k127_4443470_21	1033737.CAEV01000017_gene3207	3.439e-18	99.0	COG2244@1|root,COG2244@2|Bacteria,1V8VR@1239|Firmicutes,24BD7@186801|Clostridia,36EVG@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158338_k127_4443470_17	292459.STH1362	3.791e-36	150.0	COG1216@1|root,COG1216@2|Bacteria,1V5FQ@1239|Firmicutes,24HV0@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glycos_transf_2
SRR25158338_k127_4443470_18	330214.NIDE2873	1.023e-34	146.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wapR	-	-	ko:K12987,ko:K12988	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
SRR25158338_k127_4443470_13	525904.Tter_2804	3.922e-53	193.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	capG	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158338_k127_4443470_15	525904.Tter_2808	1.108e-49	196.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	PglL_A,Wzy_C,Wzy_C_2
SRR25158338_k127_4443470_4	525904.Tter_2807	5.169e-100	344.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158338_k127_4443470_10	247490.KSU1_C1606	7.586e-55	205.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsD	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754,ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158338_k127_4443470_2	525904.Tter_2796	1.413e-109	377.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158338_k127_4443470_3	525904.Tter_2795	1.828e-101	344.0	COG0438@1|root,COG0438@2|Bacteria,2NPSJ@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158338_k127_4443470_9	525904.Tter_2794	7.022e-79	278.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158338_k127_4443470_11	338966.Ppro_2873	8.204e-55	205.0	COG5653@1|root,COG5653@2|Bacteria,1QUMR@1224|Proteobacteria,42QYU@68525|delta/epsilon subdivisions,2WMPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM FemAB-related protein, PEP-CTERM system-associated	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR25158338_k127_4443470_23	620914.JH621310_gene55	4.651e-12	79.0	COG2273@1|root,COG5434@1|root,COG2273@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,Glyco_hydro_16,Pectate_lyase_3,RicinB_lectin_2
SRR25158338_k127_4443470_20	391038.Bphy_2053	1.357e-21	102.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_4443470_25	443255.SCLAV_4921	9.421e-07	61.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158338_k127_4443470_14	1122611.KB903965_gene5000	5.802e-51	195.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EI5A@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_445299_0	1279019.ARQK01000058_gene747	1.86e-192	617.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158338_k127_445299_2	696747.NIES39_C05180	1.115e-71	279.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
SRR25158338_k127_445299_1	324602.Caur_2337	6.16e-88	332.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SRR25158338_k127_445299_3	247634.GPB2148_32	3.111e-58	205.0	COG3631@1|root,COG3631@2|Bacteria,1RISB@1224|Proteobacteria,1SDAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_4485104_4	1128421.JAGA01000001_gene2422	1.42e-103	350.0	COG1522@1|root,COG2146@1|root,COG3253@1|root,COG1522@2|Bacteria,COG2146@2|Bacteria,COG3253@2|Bacteria,2NQGU@2323|unclassified Bacteria	2|Bacteria	K	AsnC-type helix-turn-helix domain	MA20_05845	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Chlor_dismutase,HTH_AsnC-type,Rieske
SRR25158338_k127_4485104_0	266117.Rxyl_0748	9.19e-134	434.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158338_k127_4485104_7	479434.Sthe_0398	2.631e-58	221.0	COG0730@1|root,COG0730@2|Bacteria,2G6RC@200795|Chloroflexi	200795|Chloroflexi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158338_k127_4485104_8	477974.Daud_0336	4.49e-58	209.0	COG1280@1|root,COG1280@2|Bacteria,1V725@1239|Firmicutes,24KQ7@186801|Clostridia,261QM@186807|Peptococcaceae	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158338_k127_4485104_5	479434.Sthe_2154	5.356e-99	329.0	COG0411@1|root,COG0411@2|Bacteria	2|Bacteria	E	ABC transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158338_k127_4485104_6	479434.Sthe_2153	7.184e-95	316.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,27Y8Q@189775|Thermomicrobia	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158338_k127_4485104_3	479434.Sthe_2152	1.419e-114	382.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	natD	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2
SRR25158338_k127_4485104_2	479434.Sthe_2151	4.701e-116	387.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158338_k127_4485104_1	479434.Sthe_2150	2.09e-131	436.0	COG0683@1|root,COG0683@2|Bacteria,2G7TX@200795|Chloroflexi,27YY0@189775|Thermomicrobia	189775|Thermomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158338_k127_4485104_9	1335757.SPICUR_02320	1.943e-11	71.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,1RP5V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	With LivFGHM is involved in the high affinity leucine transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158338_k127_4489597_7	298655.KI912267_gene6653	1.687e-07	59.0	29WQV@1|root,30IBV@2|Bacteria,2GZ2Y@201174|Actinobacteria,4ETJK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_4489597_0	357808.RoseRS_3083	5.795e-123	411.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158338_k127_4489597_5	351607.Acel_0042	4.886e-35	142.0	COG1765@1|root,COG1765@2|Bacteria,2HA74@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158338_k127_4489597_2	861299.J421_3656	8.263e-76	261.0	COG2102@1|root,COG2102@2|Bacteria,1ZUXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
SRR25158338_k127_4489597_3	1382356.JQMP01000003_gene1900	1.464e-52	202.0	COG2897@1|root,COG2897@2|Bacteria,2G8NA@200795|Chloroflexi,27Y2I@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158338_k127_4489597_1	370438.PTH_0203	1.351e-88	300.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,260AI@186807|Peptococcaceae	186801|Clostridia	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
SRR25158338_k127_4489597_6	7165.AGAP007238-PA	1.068e-15	83.0	COG2050@1|root,KOG3328@2759|Eukaryota,39ZWT@33154|Opisthokonta,3BQMZ@33208|Metazoa,3D78R@33213|Bilateria,420UQ@6656|Arthropoda,3SNW8@50557|Insecta,4538M@7147|Diptera,45I69@7148|Nematocera	33208|Metazoa	Q	Thioesterase-like superfamily	ACOT13	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016043,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	ko:K17362	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	4HBT
SRR25158338_k127_4489597_4	525904.Tter_0579	1.782e-35	141.0	COG0801@1|root,COG1469@1|root,COG0801@2|Bacteria,COG1469@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25	ko:K00950,ko:K09007,ko:K13940,ko:K17488	ko00790,ko01100,map00790,map01100	M00126,M00841	R00428,R03503,R03504,R04639,R05046,R05048,R10348	RC00002,RC00017,RC00263,RC00294,RC00323,RC00721,RC00943,RC00945,RC01188,RC02504,RC03131	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158338_k127_454027_5	1169161.KB897724_gene4995	1.076e-17	83.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158338_k127_454027_3	929712.KI912613_gene2392	1.607e-53	199.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CQJI@84995|Rubrobacteria	84995|Rubrobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158338_k127_454027_2	552811.Dehly_1589	1.656e-66	237.0	COG2231@1|root,COG2231@2|Bacteria,2G92S@200795|Chloroflexi,34CVI@301297|Dehalococcoidia	301297|Dehalococcoidia	L	endonuclease III	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
SRR25158338_k127_454027_4	644282.Deba_0312	2.449e-32	132.0	COG1720@1|root,COG1720@2|Bacteria,1RDUK@1224|Proteobacteria,42RNN@68525|delta/epsilon subdivisions,2WNI3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158338_k127_454027_1	243164.DET0973	3.381e-99	333.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,34CY7@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158338_k127_454027_0	745776.DGo_CA2855	5.908e-106	356.0	COG0667@1|root,COG0667@2|Bacteria,1WJFS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158338_k127_454027_7	321327.CYA_2019	1.493e-06	58.0	29ZXW@1|root,30MZF@2|Bacteria,1GNPW@1117|Cyanobacteria,1H1C9@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_454027_6	926550.CLDAP_34720	2.654e-08	56.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi	200795|Chloroflexi	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158338_k127_454503_3	42256.RradSPS_2383	3.087e-09	68.0	2CZII@1|root,32T6G@2|Bacteria,2IK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_454503_1	398525.KB900701_gene2708	6.934e-50	196.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158338_k127_454503_0	1283299.AUKG01000002_gene4334	2.686e-101	333.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
SRR25158338_k127_48181_5	224911.27355976	4.471e-07	51.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158338_k127_48181_3	318161.Sden_3305	1.142e-19	97.0	2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_48181_4	1449353.JQMQ01000005_gene1864	8.395e-11	68.0	COG1361@1|root,COG4257@1|root,COG1361@2|Bacteria,COG4257@2|Bacteria,2HERV@201174|Actinobacteria,2NKXW@228398|Streptacidiphilus	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158338_k127_48181_1	1227453.C444_19092	1.927e-41	163.0	arCOG08999@1|root,arCOG08999@2157|Archaea,2XYVR@28890|Euryarchaeota,23X8E@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_48181_2	1157943.KB892706_gene4156	7.958e-20	101.0	28JCJ@1|root,2Z977@2|Bacteria,2HQM5@201174|Actinobacteria,237HU@1762|Mycobacteriaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158338_k127_48181_0	519442.Huta_1166	9.161e-65	228.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWGR@28890|Euryarchaeota,23VES@183963|Halobacteria	183963|Halobacteria	E	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158338_k127_48181_6	351160.RCIX652	0.0003634	47.0	COG0316@1|root,arCOG04560@2157|Archaea,2XXWU@28890|Euryarchaeota,2NA1P@224756|Methanomicrobia	224756|Methanomicrobia	O	Iron-sulphur cluster biosynthesis	-	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
SRR25158338_k127_502379_0	1242864.D187_008994	0.0	1081.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158338_k127_502379_20	63737.Npun_F4488	1.795e-14	85.0	2A5JH@1|root,30U9U@2|Bacteria,1GK5Q@1117|Cyanobacteria,1HTB6@1161|Nostocales	1117|Cyanobacteria	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
SRR25158338_k127_502379_1	565033.GACE_1702	2.539e-235	751.0	COG0209@1|root,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,245VM@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
SRR25158338_k127_502379_19	1229203.KI301992_gene2499	3.359e-18	89.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria	201174|Actinobacteria	IQ	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158338_k127_502379_24	366394.Smed_0840	0.0009642	46.0	COG1359@1|root,COG1359@2|Bacteria,1N26Y@1224|Proteobacteria,2VGJ4@28211|Alphaproteobacteria,4BNKA@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158338_k127_502379_23	1121949.AQXT01000002_gene1398	1.154e-05	57.0	COG1359@1|root,COG1359@2|Bacteria,1N6JS@1224|Proteobacteria,2VGJ8@28211|Alphaproteobacteria,440SW@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158338_k127_502379_16	644283.Micau_0115	5.206e-21	99.0	COG0748@1|root,COG0748@2|Bacteria,2I6WT@201174|Actinobacteria,4DMTT@85008|Micromonosporales	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_502379_11	926560.KE387023_gene1204	1.394e-53	203.0	COG2378@1|root,COG2378@2|Bacteria,1WKYM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
SRR25158338_k127_502379_12	867903.ThesuDRAFT_01649	2.386e-53	196.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WCI6@538999|Clostridiales incertae sedis	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158338_k127_502379_10	316274.Haur_3564	5.869e-65	231.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158338_k127_502379_21	1521187.JPIM01000001_gene867	8.467e-11	65.0	COG0762@1|root,COG0762@2|Bacteria,2G9QH@200795|Chloroflexi,3760D@32061|Chloroflexia	32061|Chloroflexia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158338_k127_502379_4	871963.Desdi_2175	5.596e-146	469.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,260U5@186807|Peptococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158338_k127_502379_15	525904.Tter_0073	7.537e-26	115.0	COG2137@1|root,COG2137@2|Bacteria,2NPVT@2323|unclassified Bacteria	2|Bacteria	S	Modulates RecA activity	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT4	-	RecX
SRR25158338_k127_502379_2	479434.Sthe_0703	2.433e-171	551.0	COG1418@1|root,COG1418@2|Bacteria,2G620@200795|Chloroflexi,27Y2Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158338_k127_502379_6	255470.cbdbA1703	1.827e-83	291.0	COG1692@1|root,COG1692@2|Bacteria,2GAP9@200795|Chloroflexi,34CYI@301297|Dehalococcoidia	301297|Dehalococcoidia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158338_k127_502379_8	552811.Dehly_0011	1.708e-67	239.0	COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi,34CSU@301297|Dehalococcoidia	301297|Dehalococcoidia	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRR25158338_k127_502379_17	479434.Sthe_1748	4.765e-19	93.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi,27YJ3@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_502379_22	1120985.AUMI01000011_gene600	1.638e-09	65.0	2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4H6DK@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_502379_18	1267534.KB906755_gene4279	1.399e-18	92.0	COG2940@1|root,COG2940@2|Bacteria,3Y5G7@57723|Acidobacteria,2JMRV@204432|Acidobacteriia	204432|Acidobacteriia	S	Cysteine-rich motif following a subset of SET domains	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158338_k127_502379_5	58344.JOEL01000006_gene4685	1.978e-105	354.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_502379_7	163908.KB235896_gene286	5.396e-74	263.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158338_k127_502379_13	263358.VAB18032_12890	1.448e-34	145.0	COG2380@1|root,COG2380@2|Bacteria,2I8F9@201174|Actinobacteria,4DA01@85008|Micromonosporales	201174|Actinobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_502379_3	512565.AMIS_67940	8.587e-170	564.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
SRR25158338_k127_502379_9	471852.Tcur_1914	2.327e-65	238.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4EG3S@85012|Streptosporangiales	201174|Actinobacteria	L	Calcineurin-like phosphoesterase superfamily domain	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
SRR25158338_k127_502379_14	745776.DGo_CA1827	9.199e-32	143.0	COG0419@1|root,COG0419@2|Bacteria,1WJ38@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
SRR25158338_k127_528076_0	552811.Dehly_0744	2.652e-170	553.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi,34CNE@301297|Dehalococcoidia	301297|Dehalococcoidia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158338_k127_528076_2	255470.cbdbA581	4.27e-129	423.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi,34CWR@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158338_k127_528076_5	1172185.KB911513_gene4578	4.631e-33	142.0	COG0406@1|root,COG0406@2|Bacteria,2HNTX@201174|Actinobacteria,4G8HD@85025|Nocardiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158338_k127_528076_1	309801.trd_0422	4.151e-134	441.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi,27XPD@189775|Thermomicrobia	189775|Thermomicrobia	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
SRR25158338_k127_528076_3	269800.Tfu_1381	3.349e-56	207.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4EK42@85012|Streptosporangiales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_528076_7	1283299.AUKG01000001_gene3170	3.533e-23	102.0	COG3324@1|root,COG3324@2|Bacteria,2HRAM@201174|Actinobacteria,4CT7I@84995|Rubrobacteria	84995|Rubrobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_528076_6	926560.KE387027_gene985	5.479e-25	109.0	COG1733@1|root,COG1733@2|Bacteria,1WKTJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG1733 transcriptional regulator protein	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158338_k127_528076_9	318167.Sfri_3866	3.352e-15	81.0	COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria,2QB08@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Methyladenine glycosylase	IV02_03670	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
SRR25158338_k127_528076_4	870187.Thini_2200	5.935e-56	209.0	28MQW@1|root,2ZAZK@2|Bacteria,1MWPF@1224|Proteobacteria,1T5C9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_528076_8	556269.ACDQ01000009_gene2003	2.347e-15	76.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,473QE@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158338_k127_533935_38	1279038.KB907341_gene1907	1.612e-23	118.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria,2JZ9I@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158338_k127_533935_5	1218076.BAYB01000008_gene1507	3.617e-119	422.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Pkinase,SAM_1
SRR25158338_k127_533935_22	391626.OAN307_c26900	3.199e-56	202.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	MA20_23315	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158338_k127_533935_17	243164.DET0762	2.106e-75	261.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi,34CXZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_533935_25	1521187.JPIM01000008_gene2084	3.284e-48	186.0	COG1404@1|root,COG1404@2|Bacteria,2G7GP@200795|Chloroflexi,375SG@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM LPXTG-motif cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158338_k127_533935_31	1128421.JAGA01000002_gene1302	9.273e-36	148.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2NR31@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K21089,ko:K21972,ko:K22491	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158338_k127_533935_4	103733.JNYO01000012_gene2591	1.312e-123	404.0	COG0596@1|root,COG0596@2|Bacteria,2GNBX@201174|Actinobacteria,4EFBC@85010|Pseudonocardiales	201174|Actinobacteria	E	alpha/beta hydrolase fold	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158338_k127_533935_26	1380390.JIAT01000002_gene5973	5.586e-45	180.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,4CS4G@84995|Rubrobacteria	84995|Rubrobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158338_k127_533935_41	237368.SCABRO_01606	2.37e-10	66.0	2DNRM@1|root,32YT2@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158338_k127_533935_23	335543.Sfum_3154	3.123e-55	206.0	COG3591@1|root,COG3591@2|Bacteria,1PR15@1224|Proteobacteria,432DH@68525|delta/epsilon subdivisions,2WXPA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_533935_16	1131812.JQMS01000001_gene1971	2.204e-77	266.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia,2NTZG@237|Flavobacterium	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158338_k127_533935_37	1173023.KE650771_gene4106	1.837e-27	122.0	2AKF7@1|root,31B6Q@2|Bacteria,1G5KA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_533935_10	1120999.JONM01000002_gene637	3.868e-93	320.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,2KPXE@206351|Neisseriales	206351|Neisseriales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158338_k127_533935_27	66429.JOFL01000003_gene3442	8.388e-41	156.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158338_k127_533935_20	1229780.BN381_70010	2.869e-62	223.0	COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158338_k127_533935_8	479434.Sthe_0698	5.339e-97	328.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,27XR8@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158338_k127_533935_9	309801.trd_A0785	1.453e-93	315.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158338_k127_533935_34	406124.ACPC01000017_gene621	3.258e-29	124.0	COG0494@1|root,COG0494@2|Bacteria,1UIZV@1239|Firmicutes,4ITGK@91061|Bacilli,1ZQ2Q@1386|Bacillus	91061|Bacilli	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158338_k127_533935_36	1121928.AUHE01000001_gene1822	8.909e-28	120.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4GE94@85026|Gordoniaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	ddn	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158338_k127_533935_15	552811.Dehly_0207	9.24e-81	276.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi,34CQY@301297|Dehalococcoidia	301297|Dehalococcoidia	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158338_k127_533935_32	1121335.Clst_1426	4.466e-35	141.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158338_k127_533935_33	743718.Isova_1654	9.342e-35	147.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4F4BH@85017|Promicromonosporaceae	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158338_k127_533935_24	105425.BBPL01000003_gene6798	1.497e-49	185.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,2NG79@228398|Streptacidiphilus	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158338_k127_533935_39	756272.Plabr_3986	3.935e-21	104.0	COG1186@1|root,COG1186@2|Bacteria,2IZSY@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
SRR25158338_k127_533935_12	292459.STH404	2.159e-85	294.0	COG0702@1|root,COG0702@2|Bacteria,1VEC8@1239|Firmicutes,25BCI@186801|Clostridia	186801|Clostridia	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRR25158338_k127_533935_29	404589.Anae109_0807	2.137e-38	149.0	COG4276@1|root,COG4276@2|Bacteria,1N6EC@1224|Proteobacteria,42U3N@68525|delta/epsilon subdivisions,2WQTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158338_k127_533935_3	522306.CAP2UW1_2497	5.66e-124	416.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH1N@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_533935_40	345341.KUTG_06355	1.168e-13	76.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria,4E3VU@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158338_k127_533935_6	215803.DB30_4328	7.019e-114	382.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2YXDE@29|Myxococcales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158338_k127_533935_14	370438.PTH_2130	9.271e-83	301.0	COG2199@1|root,COG2206@1|root,COG2206@2|Bacteria,COG3706@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,267D3@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
SRR25158338_k127_533935_1	481448.Minf_0593	3.916e-157	512.0	COG0146@1|root,COG0146@2|Bacteria,46UMR@74201|Verrucomicrobia,37G2Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158338_k127_533935_2	485913.Krac_10143	2.034e-149	495.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi	200795|Chloroflexi	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158338_k127_533935_7	1499967.BAYZ01000057_gene4737	2.338e-98	332.0	COG0673@1|root,COG0673@2|Bacteria,2NRVS@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158338_k127_533935_18	1342299.Z947_87	3.926e-71	248.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2U2T5@28211|Alphaproteobacteria,3ZWM3@60136|Sulfitobacter	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158338_k127_533935_19	1123368.AUIS01000006_gene566	1.998e-70	261.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
SRR25158338_k127_533935_30	1172188.KB911820_gene3085	8.086e-36	146.0	28RB9@1|root,2ZDQU@2|Bacteria,2GZQK@201174|Actinobacteria,4FIZG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_533935_45	1397527.Q670_09385	0.000848	52.0	COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,1T1YV@1236|Gammaproteobacteria,1XS25@135619|Oceanospirillales	135619|Oceanospirillales	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
SRR25158338_k127_533935_0	1173023.KE650771_gene5138	1.327e-194	622.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JHD5@1189|Stigonemataceae	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158338_k127_533935_11	221288.JH992901_gene1075	1.224e-92	326.0	COG4191@1|root,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria,1JH5H@1189|Stigonemataceae	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
SRR25158338_k127_533935_28	1437824.BN940_03801	9.558e-39	164.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,3T8MA@506|Alcaligenaceae	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,dCache_1
SRR25158338_k127_533935_44	326424.FRAAL2742	7.976e-05	50.0	COG1475@1|root,COG1475@2|Bacteria,2IGP6@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158338_k127_533935_13	1111069.TCCBUS3UF1_17270	3.152e-84	312.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
SRR25158338_k127_533935_42	1192034.CAP_8119	1.765e-06	62.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
SRR25158338_k127_533935_21	448385.sce0969	7.518e-59	233.0	COG1409@1|root,COG1409@2|Bacteria,1R0BM@1224|Proteobacteria,43CTY@68525|delta/epsilon subdivisions,2X81I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_533935_35	279714.FuraDRAFT_1794	4.068e-28	120.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,2KQYB@206351|Neisseriales	206351|Neisseriales	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_569364_5	909663.KI867150_gene769	6.972e-24	104.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1MYKZ@1224|Proteobacteria,42SN9@68525|delta/epsilon subdivisions,2WP58@28221|Deltaproteobacteria,2MRMQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,SCP2
SRR25158338_k127_569364_7	1276920.ADIAG_02963	2.712e-06	57.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158338_k127_569364_4	525146.Ddes_0128	2.347e-53	195.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2M82V@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158338_k127_569364_1	479434.Sthe_0947	6.807e-182	582.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi,27Y49@189775|Thermomicrobia	189775|Thermomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,R3H
SRR25158338_k127_569364_8	479434.Sthe_0946	0.000184	54.0	2A40S@1|root,30SJA@2|Bacteria,2GADS@200795|Chloroflexi,27YNA@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_569364_3	326424.FRAAL2137	1.172e-59	212.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4ESCW@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158338_k127_569364_0	1380390.JIAT01000009_gene522	1.994e-266	832.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158338_k127_569364_2	479434.Sthe_0693	2.979e-79	276.0	COG1131@1|root,COG1131@2|Bacteria,2G5YX@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158338_k127_569364_6	357808.RoseRS_2477	1.931e-09	60.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi,3768D@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158338_k127_61032_30	316058.RPB_2712	0.0009642	46.0	2AFVV@1|root,315YK@2|Bacteria,1NQAN@1224|Proteobacteria,2UNGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_61032_24	649638.Trad_2042	2.641e-49	193.0	COG0388@1|root,COG0388@2|Bacteria,1WJ47@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158338_k127_61032_18	1128421.JAGA01000002_gene1741	1.7e-63	230.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158338_k127_61032_25	285514.JNWO01000035_gene7278	6.49e-46	179.0	COG0346@1|root,COG0346@2|Bacteria,2GRGB@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158338_k127_61032_26	1003195.SCAT_2919	6.326e-28	125.0	COG0346@1|root,COG0346@2|Bacteria,2I8Q5@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_61032_6	1347368.HG964407_gene6685	1.051e-96	329.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,1ZCAI@1386|Bacillus	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158338_k127_61032_20	479434.Sthe_1642	3.215e-60	218.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,27Y5S@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158338_k127_61032_14	29540.C481_00815	1.56e-69	249.0	COG0111@1|root,arCOG01757@2157|Archaea,2XTC4@28890|Euryarchaeota,23STD@183963|Halobacteria	183963|Halobacteria	H	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158338_k127_61032_7	1382306.JNIM01000001_gene910	7.692e-96	331.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158338_k127_61032_27	47763.JNZA01000005_gene4711	1.267e-22	100.0	COG4274@1|root,COG4274@2|Bacteria,2IN0N@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158338_k127_61032_2	1267535.KB906767_gene3674	2.892e-113	380.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158338_k127_61032_23	797302.Halru_0296	3.263e-52	198.0	COG1028@1|root,arCOG01259@2157|Archaea,2XUNT@28890|Euryarchaeota,23U46@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158338_k127_61032_11	1343740.M271_38100	1.54e-88	303.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158338_k127_61032_12	1336208.JADY01000002_gene560	6.749e-88	296.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,2JV11@204441|Rhodospirillales	204441|Rhodospirillales	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158338_k127_61032_0	1121422.AUMW01000014_gene1319	3.157e-145	471.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158338_k127_61032_29	1230342.CTM_20751	0.0002251	51.0	2DQT5@1|root,338GV@2|Bacteria,1VEES@1239|Firmicutes,24S7P@186801|Clostridia,36MZH@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_61032_15	1382356.JQMP01000001_gene774	2.356e-69	242.0	COG0745@1|root,COG0745@2|Bacteria,2GABY@200795|Chloroflexi,27Z4B@189775|Thermomicrobia	189775|Thermomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158338_k127_61032_17	479434.Sthe_0750	6.154e-68	246.0	COG5002@1|root,COG5002@2|Bacteria,2G6F5@200795|Chloroflexi,27Z71@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158338_k127_61032_16	1205680.CAKO01000002_gene2638	5.429e-69	244.0	COG0346@1|root,COG0346@2|Bacteria,1R9XW@1224|Proteobacteria,2U6IT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158338_k127_61032_28	1131266.ARWQ01000002_gene618	8.807e-15	78.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41TA2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_61032_9	1123070.KB899247_gene1649	5.474e-91	311.0	COG1611@1|root,COG1611@2|Bacteria,46SEG@74201|Verrucomicrobia,2ITGC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158338_k127_61032_4	1121372.AULK01000001_gene2308	3.616e-97	331.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4FKWX@85023|Microbacteriaceae	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158338_k127_61032_21	1122221.JHVI01000001_gene1835	6.927e-60	228.0	COG2202@1|root,COG3437@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
SRR25158338_k127_61032_19	589924.Ferp_1233	4.289e-61	220.0	COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,2469N@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158338_k127_61032_10	1896.JOAU01000026_gene3351	9.694e-89	309.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	strS	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158338_k127_61032_22	586413.CCDL010000001_gene575	1.804e-52	198.0	COG3266@1|root,COG3266@2|Bacteria,1UYHI@1239|Firmicutes,4HFF7@91061|Bacilli,23MVV@182709|Oceanobacillus	91061|Bacilli	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_61032_5	926550.CLDAP_26140	9.507e-97	327.0	COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158338_k127_61032_13	234267.Acid_1485	1.887e-73	259.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158338_k127_61032_1	472759.Nhal_1953	6.612e-130	430.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1WZZP@135613|Chromatiales	135613|Chromatiales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158338_k127_61032_8	644283.Micau_1734	7.02e-93	318.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,4DBDY@85008|Micromonosporales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158338_k127_61032_3	1194165.CAJF01000035_gene1765	1.436e-112	372.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FM6W@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldC	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158338_k127_64140_4	552811.Dehly_0973	3.849e-83	282.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi,34CP1@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158338_k127_64140_10	1038867.AXAY01000004_gene2524	3.196e-56	213.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,3JS33@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	MA20_18620	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158338_k127_64140_11	1206732.BAGD01000113_gene5078	1.224e-55	211.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4FZUX@85025|Nocardiaceae	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158338_k127_64140_9	1121106.JQKB01000020_gene1994	4.126e-64	237.0	COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2TUBF@28211|Alphaproteobacteria,2JUXE@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158338_k127_64140_3	1122611.KB903957_gene52	7.23e-84	288.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4EIQD@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158338_k127_64140_5	224911.27356214	9.796e-83	281.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3JUH1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	MA20_19430	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,DLIC
SRR25158338_k127_64140_6	1408164.MOLA814_02200	2.039e-75	261.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VNH8@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158338_k127_64140_1	255470.cbdbA583	1.099e-133	438.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,34D17@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158338_k127_64140_7	357808.RoseRS_3756	2.636e-75	267.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158338_k127_64140_8	485913.Krac_12559	6.974e-70	249.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158338_k127_64140_2	485915.Dret_1480	1.257e-88	316.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2M7YC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158338_k127_64140_13	926550.CLDAP_29850	1.434e-31	136.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158338_k127_64140_0	326427.Cagg_2935	3.29e-135	439.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi,3757M@32061|Chloroflexia	32061|Chloroflexia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158338_k127_64140_12	309801.trd_0109	2.274e-41	156.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,27YKI@189775|Thermomicrobia	189775|Thermomicrobia	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158338_k127_64140_14	1382356.JQMP01000004_gene436	2.271e-26	111.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,27XSP@189775|Thermomicrobia	189775|Thermomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158338_k127_718329_1	1128421.JAGA01000002_gene455	2.867e-108	371.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158338_k127_718329_0	429009.Adeg_1948	4.375e-180	571.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158338_k127_731591_8	222534.KB893738_gene1273	1.097e-24	105.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4ES3N@85013|Frankiales	201174|Actinobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
SRR25158338_k127_731591_4	266117.Rxyl_0760	6.415e-54	199.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158338_k127_731591_0	1449126.JQKL01000009_gene363	2.15e-114	391.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26ARS@186813|unclassified Clostridiales	186801|Clostridia	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158338_k127_731591_7	40571.JOEA01000005_gene4257	5.648e-28	120.0	COG5637@1|root,COG5637@2|Bacteria,2I3U7@201174|Actinobacteria,4E5IY@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158338_k127_731591_12	266809.PM03_06465	0.0005536	46.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158338_k127_731591_10	684949.ATTJ01000001_gene2085	2.502e-10	65.0	COG2128@1|root,COG2128@2|Bacteria,1WJIC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158338_k127_731591_6	1002809.SSIL_0823	9.545e-34	147.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,26EBR@186818|Planococcaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF1080,GDPD
SRR25158338_k127_731591_1	309799.DICTH_0359	1.344e-105	357.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158338_k127_731591_5	309801.trd_A0910	1.424e-42	162.0	COG1881@1|root,COG1881@2|Bacteria,2G6ZP@200795|Chloroflexi,27Z5Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158338_k127_731591_11	1146883.BLASA_2019	2.069e-08	66.0	COG4961@1|root,COG4961@2|Bacteria,2I702@201174|Actinobacteria	201174|Actinobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158338_k127_731591_3	457570.Nther_2059	5.074e-62	233.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158338_k127_731591_2	222534.KB893711_gene5041	9.084e-79	279.0	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4ESEF@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158338_k127_731591_9	1192034.CAP_6141	5.721e-14	83.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158338_k127_917375_6	1307759.JOMJ01000004_gene2740	5.201e-07	52.0	2A8NA@1|root,30XQU@2|Bacteria,1QB6P@1224|Proteobacteria,436A7@68525|delta/epsilon subdivisions,2X0V2@28221|Deltaproteobacteria,2MDPY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158338_k127_917375_7	309801.trd_A0832	3.592e-06	52.0	COG2331@1|root,COG2331@2|Bacteria,2G7IB@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158338_k127_917375_3	255470.cbdbA557	1.361e-49	190.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,34CSZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158338_k127_917375_1	635013.TherJR_0070	5.587e-82	277.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,2612W@186807|Peptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158338_k127_917375_5	479437.Elen_0604	1.239e-23	111.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4CWBC@84998|Coriobacteriia	84998|Coriobacteriia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158338_k127_917375_0	243164.DET0585	5.217e-101	349.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi,34CSC@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158338_k127_917375_4	383372.Rcas_4283	2.005e-31	128.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi,375VQ@32061|Chloroflexia	32061|Chloroflexia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158338_k127_917375_2	552811.Dehly_0841	2.371e-73	255.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi,34D3B@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158338_k127_918747_5	311424.DhcVS_1440	4.232e-56	198.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi,34CT7@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158338_k127_918747_3	1382356.JQMP01000003_gene2027	2.469e-60	218.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158338_k127_918747_2	1259795.ARJK01000004_gene1341	8.577e-68	260.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
SRR25158338_k127_918747_1	1210884.HG799462_gene7991	1.119e-84	289.0	COG1351@1|root,COG1351@2|Bacteria,2J0W9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158338_k127_918747_0	479434.Sthe_3482	1.431e-140	455.0	COG2041@1|root,COG2041@2|Bacteria,2GB1N@200795|Chloroflexi,27Z7Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158338_k127_918747_4	1173026.Glo7428_3084	2.981e-59	216.0	COG3217@1|root,COG3217@2|Bacteria,1G56F@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158338_k127_997530_2	1236689.MMALV_01900	5.597e-90	306.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158338_k127_997530_4	1005999.GLGR_3685	4.943e-55	209.0	COG2227@1|root,COG2227@2|Bacteria,1QYHT@1224|Proteobacteria,1T3QK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158338_k127_997530_1	331678.Cphamn1_1310	7e-116	383.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158338_k127_997530_3	861299.J421_0542	2.288e-75	259.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158338_k127_997530_0	309801.trd_1064	6.8e-144	469.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi,27XJI@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158338_k127_99932_6	1128421.JAGA01000002_gene1504	9.668e-43	172.0	COG0352@1|root,COG0352@2|Bacteria,2NPCU@2323|unclassified Bacteria	2|Bacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00788,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158338_k127_99932_4	43354.JOIJ01000026_gene3305	1.116e-58	213.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4E4PW@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.304,1.1.1.76	ko:K03366	ko00650,map00650	-	R02855,R02946,R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158338_k127_99932_10	926569.ANT_19700	1.38e-18	94.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158338_k127_99932_3	1333998.M2A_2493	1.506e-122	406.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,4BTBG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158338_k127_99932_8	172088.AUGA01000048_gene911	5.448e-28	120.0	2CJ4Q@1|root,32S97@2|Bacteria,1N0B9@1224|Proteobacteria,2U72B@28211|Alphaproteobacteria,3K0TV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
SRR25158338_k127_99932_5	886293.Sinac_7551	8.817e-49	193.0	COG0491@1|root,COG0491@2|Bacteria,2J4KU@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158338_k127_99932_2	342949.PNA2_0671	1.48e-123	412.0	COG3653@1|root,arCOG00690@2157|Archaea,2XVS0@28890|Euryarchaeota,2451W@183968|Thermococci	183968|Thermococci	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158338_k127_99932_0	497964.CfE428DRAFT_0990	1.86e-227	727.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR25158338_k127_99932_7	311424.DhcVS_47	8.785e-38	155.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi,34D0N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158338_k127_99932_1	243164.DET0830	9.41e-198	628.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi,34CY8@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158338_k127_99932_9	264732.Moth_1350	7.792e-26	107.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,42EVA@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
## 1589 queries scanned
## Total time (seconds): 8.66921091079712
## Rate: 183.29 q/s