## Sun Dec 14 08:10:05 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158343_bin.18.fa -m mmseqs --itype genome -o SRR25158343_bin.18 --output_dir /data/result/bins/wyx/egg/SRR25158343_bin.18 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158343_k127_1069035_1	121225.PHUM390660-PA	3.39e-187	614.0	COG0308@1|root,KOG1046@2759|Eukaryota,38CFG@33154|Opisthokonta,3BADC@33208|Metazoa,3CW5S@33213|Bilateria,41WW7@6656|Arthropoda,3SGEA@50557|Insecta,3E9UH@33342|Paraneoptera	33208|Metazoa	E	ERAP1-like C-terminal domain	NPEPPS	GO:0000003,GO:0000209,GO:0000578,GO:0000793,GO:0000922,GO:0001666,GO:0003002,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007350,GO:0007351,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008595,GO:0009056,GO:0009628,GO:0009790,GO:0009792,GO:0009798,GO:0009880,GO:0009948,GO:0009952,GO:0009987,GO:0010564,GO:0010720,GO:0015630,GO:0016567,GO:0016787,GO:0019538,GO:0022402,GO:0022414,GO:0030588,GO:0030590,GO:0032446,GO:0032501,GO:0032502,GO:0033218,GO:0033554,GO:0034641,GO:0035282,GO:0036211,GO:0036293,GO:0036294,GO:0042221,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043603,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044771,GO:0045595,GO:0045597,GO:0046662,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050896,GO:0051094,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051321,GO:0051445,GO:0051640,GO:0051641,GO:0051642,GO:0051651,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0060281,GO:0060282,GO:0060284,GO:0061842,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070482,GO:0070647,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0072686,GO:0097431,GO:0140096,GO:1900193,GO:1900195,GO:1901564,GO:1901565,GO:1901575,GO:1903046,GO:1903429,GO:1903431,GO:1903538,GO:1905879,GO:1905881,GO:1990947,GO:2000241,GO:2000243	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158343_k127_1069035_3	525904.Tter_0912	1.008e-87	304.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158343_k127_1069035_6	1540257.JQMW01000009_gene2772	1.109e-28	135.0	COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,36DKS@31979|Clostridiaceae	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	HNH,Helicase_C,ResIII
SRR25158343_k127_1069035_0	1094508.Tsac_0980	5.343e-236	755.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158343_k127_1069035_5	1173020.Cha6605_2906	8.428e-47	182.0	COG1196@1|root,COG1196@2|Bacteria,1GENB@1117|Cyanobacteria	1117|Cyanobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1069035_2	1235792.C808_01657	6.374e-118	394.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,27IX4@186928|unclassified Lachnospiraceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158343_k127_1069035_4	316274.Haur_3225	4.116e-51	207.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,374XI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158343_k127_1074399_6	1278308.KB907083_gene362	1.175e-24	119.0	COG1807@1|root,COG1807@2|Bacteria,2H5NR@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1074399_0	1283283.ATXA01000004_gene4336	3.177e-134	435.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158343_k127_1074399_4	926569.ANT_06180	3.251e-34	149.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158343_k127_1074399_9	1274524.BSONL12_05258	1.973e-14	82.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4HDG1@91061|Bacilli,1ZCQ7@1386|Bacillus	91061|Bacilli	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914,ko:K21828	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_1074399_8	632335.Calkr_0253	1.621e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,42EYI@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1074399_3	316274.Haur_4061	1.431e-53	203.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158343_k127_1074399_7	710696.Intca_0836	3.776e-20	102.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4FG47@85021|Intrasporangiaceae	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158343_k127_1074399_2	909663.KI867150_gene225	2.04e-68	240.0	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,42US7@68525|delta/epsilon subdivisions,2X9TS@28221|Deltaproteobacteria,2MRK3@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158343_k127_1074399_1	1340493.JNIF01000003_gene1483	4.804e-98	327.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_1074399_5	246194.CHY_1491	2.357e-32	130.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
SRR25158343_k127_1110305_3	911104.AEKT01000004_gene1269	1.178e-19	91.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,4AXV2@81850|Leuconostocaceae	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158343_k127_1110305_1	1541959.KQ51_00213	1.672e-40	157.0	COG0098@1|root,COG0098@2|Bacteria,3WTIC@544448|Tenericutes	544448|Tenericutes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158343_k127_1110305_2	1071073.KI530535_gene448	4.114e-24	107.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158343_k127_1110305_0	1089453.GOSPT_122_00050	4.127e-69	248.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4GBHR@85026|Gordoniaceae	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158343_k127_1110654_2	1417296.U879_09905	5.186e-18	88.0	COG1018@1|root,COG1018@2|Bacteria,1PEWB@1224|Proteobacteria,2UGW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1,NQR2_RnfD_RnfE
SRR25158343_k127_1110654_5	1484158.PSNIH1_11650	0.0001	51.0	COG1846@1|root,COG1846@2|Bacteria,1N24F@1224|Proteobacteria,1S2I6@1236|Gammaproteobacteria,3W2SR@53335|Pantoea	1236|Gammaproteobacteria	K	MarR family transcriptional regulator	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
SRR25158343_k127_1110654_0	264732.Moth_2420	2.29e-78	273.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_1110654_4	935836.JAEL01000049_gene5368	7.412e-09	60.0	COG0695@1|root,COG0695@2|Bacteria,1VIGD@1239|Firmicutes,4HNUE@91061|Bacilli,1ZHUC@1386|Bacillus	91061|Bacilli	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158343_k127_1110654_1	1229780.BN381_350110	1.421e-28	121.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,3UWVE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158343_k127_1110654_3	745776.DGo_CA2685	4.601e-15	81.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158343_k127_112736_3	1034345.CAEM01000009_gene1280	1.46e-45	168.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CVR4@84998|Coriobacteriia	84998|Coriobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158343_k127_112736_4	1246955.MCYN_0095	2.217e-29	121.0	COG0103@1|root,COG0103@2|Bacteria,3WTKX@544448|Tenericutes	544448|Tenericutes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158343_k127_112736_0	477641.MODMU_2044	6.048e-120	399.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria	201174|Actinobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158343_k127_112736_1	443218.AS9A_3982	1.073e-71	254.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,2330H@1762|Mycobacteriaceae	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158343_k127_112736_2	243164.DET1375	7.133e-52	194.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,34D96@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_112736_5	1443122.Z958_10045	4.695e-18	94.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,36DG8@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158343_k127_1180661_0	370438.PTH_2737	0.0	1173.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158343_k127_1180661_3	754476.Q7A_877	2.597e-109	370.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,4601T@72273|Thiotrichales	72273|Thiotrichales	L	Exonuclease C-terminal	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
SRR25158343_k127_1180661_2	264732.Moth_0561	9.1e-112	374.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158343_k127_1180661_7	1167632.AJTR01000091_gene2501	2.871e-22	109.0	COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli,4GXBH@90964|Staphylococcaceae	91061|Bacilli	M	CHAP domain	-	-	3.5.1.28	ko:K22409	-	-	-	-	ko00000,ko01000	-	CBM50	-	CHAP,LysM
SRR25158343_k127_1180661_6	477974.Daud_0918	8.671e-43	170.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,260MF@186807|Peptococcaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158343_k127_1180661_8	326427.Cagg_0094	2.379e-16	84.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,375V0@32061|Chloroflexia	32061|Chloroflexia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158343_k127_1180661_5	1382306.JNIM01000001_gene244	1.602e-82	290.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
SRR25158343_k127_1180661_1	1828.JOKB01000065_gene4599	1.08e-183	593.0	COG0013@1|root,COG0013@2|Bacteria,2H29T@201174|Actinobacteria,4G5Y1@85025|Nocardiaceae	201174|Actinobacteria	J	tRNA synthetases class II (A)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2c
SRR25158343_k127_1180661_4	1321773.HMPREF9069_01654	4.206e-106	354.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4CU8F@84998|Coriobacteriia	84998|Coriobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158343_k127_1180661_9	1158609.I586_02370	2.242e-06	59.0	COG4072@1|root,COG4072@2|Bacteria,1V1VN@1239|Firmicutes,4HG8P@91061|Bacilli,4B0IK@81852|Enterococcaceae	91061|Bacilli	S	Protein of unknown function C-terminal (DUF3324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3324,DUF916
SRR25158343_k127_1200023_1	556268.OFAG_00272	4.008e-36	144.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,472XF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158343_k127_1200023_7	1408439.JHXW01000016_gene79	1.306e-11	66.0	COG0227@1|root,COG0227@2|Bacteria,37AJS@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158343_k127_1200023_6	383372.Rcas_2962	5.832e-15	83.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,375G8@32061|Chloroflexia	32061|Chloroflexia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158343_k127_1200023_5	572547.Amico_1736	3.649e-16	86.0	COG0640@1|root,COG0640@2|Bacteria,3TAVK@508458|Synergistetes	508458|Synergistetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1200023_0	345219.Bcoa_3306	1.152e-52	196.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158343_k127_1200023_3	525904.Tter_0337	1.21e-21	98.0	COG3695@1|root,COG3695@2|Bacteria,2NRVD@2323|unclassified Bacteria	2|Bacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158343_k127_1200023_2	314275.MADE_1003090	3.409e-22	98.0	COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,1SDK6@1236|Gammaproteobacteria,46C7D@72275|Alteromonadaceae	1236|Gammaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158343_k127_1200023_8	111780.Sta7437_0529	0.0003961	46.0	2CAX8@1|root,33CC9@2|Bacteria,1GB0V@1117|Cyanobacteria,3VN6J@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1200023_4	1444309.JAQG01000073_gene241	1.437e-18	89.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,26QJC@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158343_k127_1210558_2	1288963.ADIS_1705	9.674e-77	273.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
SRR25158343_k127_1210558_0	563192.HMPREF0179_03201	1.089e-139	454.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
SRR25158343_k127_1210558_1	429009.Adeg_0202	2.074e-126	427.0	COG3387@1|root,COG3387@2|Bacteria,1TSFD@1239|Firmicutes,24EW4@186801|Clostridia,42F5M@68295|Thermoanaerobacterales	186801|Clostridia	G	glycoside hydrolase 15-related	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
SRR25158343_k127_1210558_3	1423734.JCM14202_1434	6.461e-13	70.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158343_k127_1210558_5	1121019.AUMN01000038_gene23	1.091e-05	48.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158343_k127_1210558_4	204669.Acid345_2490	5.141e-12	77.0	COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria,2JHXJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158343_k127_1303577_1	1120959.ATXF01000006_gene1849	4.971e-06	55.0	COG1876@1|root,COG1876@2|Bacteria,2IN2C@201174|Actinobacteria,4FM2A@85023|Microbacteriaceae	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158343_k127_1303577_0	537007.BLAHAN_04260	2.208e-16	94.0	COG3023@1|root,COG3087@1|root,COG3023@2|Bacteria,COG3087@2|Bacteria,1TRDG@1239|Firmicutes,24ABM@186801|Clostridia,3Y1VZ@572511|Blautia	186801|Clostridia	V	Cpl-7 lysozyme C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_7,SH3_5,SPOR
SRR25158343_k127_1308090_3	313589.JNB_04640	4.333e-41	169.0	2AJP3@1|root,31AAI@2|Bacteria,2GPNW@201174|Actinobacteria,4FIWB@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1308090_4	404380.Gbem_1799	2.457e-13	83.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,fn3
SRR25158343_k127_1308090_2	1480694.DC28_08810	2.542e-43	168.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158343_k127_1308090_0	1278073.MYSTI_04345	1.659e-77	275.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_1308090_1	1485544.JQKP01000002_gene1623	2.751e-57	210.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158343_k127_1311537_0	1157490.EL26_22055	1.57e-76	267.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,277VV@186823|Alicyclobacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158343_k127_1311537_5	938288.HG326229_gene63	3.664e-11	64.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158343_k127_1311537_7	321332.CYB_2941	9.169e-06	55.0	COG0594@1|root,COG0594@2|Bacteria,1GP6I@1117|Cyanobacteria,1H2C8@1129|Synechococcus	1117|Cyanobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158343_k127_1311537_3	665959.HMPREF1013_01843	3.072e-17	93.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158343_k127_1311537_2	391625.PPSIR1_35072	5.928e-20	96.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158343_k127_1311537_6	111780.Sta7437_2886	6.253e-09	60.0	COG3041@1|root,COG3041@2|Bacteria,1G7V7@1117|Cyanobacteria,3VMW8@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Plasmid maintenance system killer protein	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
SRR25158343_k127_1311537_1	204669.Acid345_1265	2.379e-56	210.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria,2JJTZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1311537_4	1122237.AUGQ01000008_gene205	1.695e-15	81.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4FKX7@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158343_k127_1382554_1	7370.XP_005184556.1	1.686e-83	293.0	COG0519@1|root,KOG1622@2759|Eukaryota,38DHS@33154|Opisthokonta,3BDTV@33208|Metazoa,3CW4N@33213|Bilateria,41TJK@6656|Arthropoda,3SJCG@50557|Insecta,45197@7147|Diptera	33208|Metazoa	F	activity. It is involved in the biological process described with GMP biosynthetic process	GMPS	GO:0000902,GO:0000904,GO:0001101,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005700,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006177,GO:0006325,GO:0006464,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006996,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010952,GO:0016043,GO:0016504,GO:0016569,GO:0016570,GO:0016578,GO:0016579,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0022008,GO:0030030,GO:0030154,GO:0030162,GO:0030182,GO:0030234,GO:0031175,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0035800,GO:0036211,GO:0040011,GO:0042221,GO:0042278,GO:0042330,GO:0042440,GO:0042451,GO:0042455,GO:0042493,GO:0043085,GO:0043170,GO:0043200,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046037,GO:0046112,GO:0046128,GO:0046129,GO:0046148,GO:0046390,GO:0046483,GO:0048468,GO:0048518,GO:0048522,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051276,GO:0051336,GO:0051345,GO:0052547,GO:0055086,GO:0060255,GO:0061134,GO:0061564,GO:0065007,GO:0065009,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097485,GO:0098772,GO:0120036,GO:0120039,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901367,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:2000152,GO:2000158	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158343_k127_1382554_0	1125863.JAFN01000001_gene2927	1.129e-137	450.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_1384384_0	633147.Olsu_0349	4.57e-109	374.0	COG5265@1|root,COG5265@2|Bacteria,2I6AF@201174|Actinobacteria,4CUQX@84998|Coriobacteriia	84998|Coriobacteriia	O	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1384384_2	644284.Arch_1519	1.949e-14	83.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4D4B1@85005|Actinomycetales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158343_k127_1384384_1	319795.Dgeo_2482	7.883e-50	184.0	COG0586@1|root,COG0586@2|Bacteria,1WKEG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158343_k127_138462_1	1123405.AUMM01000001_gene32	1.658e-132	438.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,26NEU@186821|Sporolactobacillaceae	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158343_k127_138462_4	1121344.JHZO01000005_gene99	4.27e-23	100.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158343_k127_138462_3	382464.ABSI01000010_gene3686	1.906e-52	193.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,2ITQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
SRR25158343_k127_138462_6	543734.LCABL_29790	4.871e-05	56.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae	91061|Bacilli	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_138462_7	443254.Marpi_1095	0.0001792	48.0	COG0268@1|root,COG0268@2|Bacteria,2GDFA@200918|Thermotogae	200918|Thermotogae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158343_k127_138462_5	97137.C821_00883	6.939e-16	88.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158343_k127_138462_0	667014.Thein_0592	2.062e-184	604.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,2GH2W@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Trehalose-phosphatase	-	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158343_k127_138462_2	1423815.BACR01000006_gene353	4.652e-53	195.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158343_k127_1410769_1	862908.BMS_0446	1.603e-101	346.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2MT5M@213481|Bdellovibrionales,2WJE1@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158343_k127_1410769_4	471856.Jden_2427	1.085e-26	117.0	COG1073@1|root,COG1073@2|Bacteria,2H6JI@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1410769_7	1174504.AJTN02000176_gene2071	0.0008668	42.0	29S7Z@1|root,30DCG@2|Bacteria,1UB50@1239|Firmicutes,4IMHI@91061|Bacilli,1ZK63@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1410769_5	1380390.JIAT01000010_gene4224	1.778e-26	115.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158343_k127_1410769_0	525904.Tter_1650	4.197e-156	515.0	COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria	2|Bacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158343_k127_1410769_3	345341.KUTG_01907	2.19e-92	310.0	COG0500@1|root,COG2226@2|Bacteria,2IGXK@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1410769_2	471852.Tcur_2160	4.541e-97	331.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4EFWJ@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158343_k127_1410769_6	1303518.CCALI_01448	1.367e-16	87.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.4.1.129,3.4.16.4	ko:K03693,ko:K03814,ko:K04478,ko:K05365,ko:K05366,ko:K05367,ko:K12551,ko:K12555,ko:K18770,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_1671	Transgly,Transpeptidase
SRR25158343_k127_1445962_1	1120971.AUCA01000031_gene158	7.177e-45	173.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,2787M@186823|Alicyclobacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRR25158343_k127_1445962_3	251229.Chro_1883	2.825e-19	102.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PG_binding_1,Response_reg,dCache_1
SRR25158343_k127_1445962_2	525904.Tter_0689	7.518e-41	159.0	COG1187@1|root,COG1187@2|Bacteria,2NPCM@2323|unclassified Bacteria	2|Bacteria	J	RNA pseudouridylate synthase	rluE	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_1445962_0	1188240.MYEA_0580	6.228e-58	211.0	COG1160@1|root,COG1160@2|Bacteria,3WSVN@544448|Tenericutes	544448|Tenericutes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	engA	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158343_k127_1448487_1	1268635.Loa_02895	6.832e-51	191.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1JCPD@118969|Legionellales	118969|Legionellales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158343_k127_1448487_0	573061.Clocel_3049	2.977e-200	633.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,36ERS@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158343_k127_1448487_3	720554.Clocl_0302	3.822e-07	57.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3WJYM@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158343_k127_1448487_2	1183438.GKIL_3645	2.862e-49	178.0	COG1970@1|root,COG1970@2|Bacteria,1G829@1117|Cyanobacteria	1117|Cyanobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158343_k127_1452250_0	941824.TCEL_02023	6.26e-234	740.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,36DYE@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158343_k127_1462157_0	635013.TherJR_2331	9.244e-265	853.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158343_k127_1462157_1	1155718.KB891881_gene5695	1.645e-19	99.0	COG2340@1|root,COG2340@2|Bacteria,2IE0J@201174|Actinobacteria	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158343_k127_1462157_2	1288963.ADIS_0844	7.658e-10	61.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,47QCV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158343_k127_1553029_1	1236973.JCM9157_4780	7.802e-22	104.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZAPC@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	spsB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158343_k127_1553029_0	326427.Cagg_3186	2.241e-29	135.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,376MC@32061|Chloroflexia	32061|Chloroflexia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158343_k127_1553029_2	865861.AZSU01000006_gene1357	1.266e-18	94.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,36DM2@31979|Clostridiaceae	186801|Clostridia	O	PDZ DHR GLGF domain protein	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_1594412_2	1121952.ATXT01000016_gene538	5.958e-52	204.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria,4FKPX@85023|Microbacteriaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158343_k127_1594412_0	309803.CTN_1244	1.846e-89	307.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GC4M@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158343_k127_1594412_6	999541.bgla_2g26240	6.691e-25	110.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSKZ@28216|Betaproteobacteria,1K7VI@119060|Burkholderiaceae	28216|Betaproteobacteria	M	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
SRR25158343_k127_1594412_8	1321778.HMPREF1982_00918	6.527e-09	60.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes	1239|Firmicutes	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158343_k127_1594412_1	264732.Moth_2420	1.075e-73	259.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_1594412_4	485913.Krac_7104	2.862e-36	146.0	COG1018@1|root,COG1018@2|Bacteria,2G9BE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
SRR25158343_k127_1594412_7	1122134.KB893650_gene1173	4.081e-23	107.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,1XK3A@135619|Oceanospirillales	135619|Oceanospirillales	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158343_k127_1594412_3	1128421.JAGA01000003_gene2959	3.575e-40	154.0	COG0221@1|root,COG0221@2|Bacteria,2NPVX@2323|unclassified Bacteria	2|Bacteria	C	Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158343_k127_1594412_5	1123013.AUIC01000004_gene1752	5.743e-35	141.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3067,iE2348C_1286.E2348C_3641,iECABU_c1320.ECABU_c38150,iECED1_1282.ECED1_4056,iECNA114_1301.ECNA114_3494,iECOK1_1307.ECOK1_3810,iECP_1309.ECP_3483,iECS88_1305.ECS88_3783,iECSF_1327.ECSF_3218,iLF82_1304.LF82_1531,iNRG857_1313.NRG857_16815,iUMN146_1321.UM146_17040,iUTI89_1310.UTI89_C3895,ic_1306.c4167	NUDIX
SRR25158343_k127_1642648_4	765952.PUV_18030	1.587e-19	97.0	COG1961@1|root,COG1961@2|Bacteria,2JGRW@204428|Chlamydiae	204428|Chlamydiae	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase,Zn_ribbon_recom
SRR25158343_k127_1642648_6	1242864.D187_007089	4.48e-06	58.0	COG2267@1|root,COG2267@2|Bacteria,1MZG8@1224|Proteobacteria,42P0T@68525|delta/epsilon subdivisions,2WJ45@28221|Deltaproteobacteria,2YU6Y@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158343_k127_1642648_2	1123355.JHYO01000032_gene11	1.908e-65	237.0	COG0438@1|root,COG0438@2|Bacteria,1PEAE@1224|Proteobacteria,2TRDN@28211|Alphaproteobacteria,370MI@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1642648_0	1095772.CAHH01000009_gene2174	1.495e-91	314.0	COG0438@1|root,COG0438@2|Bacteria,2GP0E@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1642648_3	287986.DV20_12625	4.297e-40	163.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4DZ3V@85010|Pseudonocardiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158343_k127_1642648_1	234267.Acid_3249	4.937e-85	299.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158343_k127_1642648_5	574087.Acear_1594	5.127e-13	77.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WAJB@53433|Halanaerobiales	186801|Clostridia	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_1643030_2	1304284.L21TH_1218	3.848e-56	205.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,36DIA@31979|Clostridiaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
SRR25158343_k127_1643030_0	646529.Desaci_4574	2.723e-111	373.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158343_k127_1643030_1	387092.NIS_1773	1.41e-69	250.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2YMCR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158343_k127_1674676_6	160488.PP_3706	2.73e-37	153.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,1SAUJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	Ribosomal protein S6 modification	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_1674676_1	593907.Celgi_1774	9.251e-113	376.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4F0YK@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158343_k127_1674676_7	797209.ZOD2009_10725	6.638e-14	81.0	arCOG08617@1|root,arCOG08617@2157|Archaea,2XW39@28890|Euryarchaeota,23SYN@183963|Halobacteria	183963|Halobacteria	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158343_k127_1674676_5	469383.Cwoe_5524	1.631e-72	255.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4CS0Z@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1674676_3	157072.XP_008866214.1	2.52e-90	311.0	COG0111@1|root,KOG0068@2759|Eukaryota	2759|Eukaryota	EH	phosphoglycerate dehydrogenase activity	SER33	GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0061759,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158343_k127_1674676_2	1423732.BALS01000050_gene2901	4.769e-112	374.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae	91061|Bacilli	L	recombination factor protein RarA	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158343_k127_1674676_8	742740.HMPREF9474_00857	1.938e-06	59.0	COG1896@1|root,COG1896@2|Bacteria,1V4MY@1239|Firmicutes,25CES@186801|Clostridia,21ZYN@1506553|Lachnoclostridium	186801|Clostridia	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158343_k127_1674676_4	1236973.JCM9157_1584	2.383e-87	302.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus	91061|Bacilli	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158343_k127_1674676_0	485913.Krac_10794	4.497e-187	600.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_1705170_1	390989.JOEG01000001_gene4876	6.346e-57	203.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DD25@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158343_k127_1705170_3	312284.A20C1_12219	1.047e-33	140.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158343_k127_1705170_2	48698.ENSPFOP00000018964	3.279e-43	170.0	COG1253@1|root,KOG2118@2759|Eukaryota,38BRM@33154|Opisthokonta,3BFQM@33208|Metazoa,3CSQT@33213|Bilateria,48875@7711|Chordata,48WYF@7742|Vertebrata,4A1YS@7898|Actinopterygii	33208|Metazoa	S	Cyclin and CBS domain divalent metal cation transport mediator	CNNM4	GO:0000003,GO:0003006,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0007275,GO:0007548,GO:0007568,GO:0008150,GO:0008324,GO:0008340,GO:0008406,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010035,GO:0010038,GO:0010259,GO:0010960,GO:0015075,GO:0015077,GO:0015081,GO:0015095,GO:0015318,GO:0015672,GO:0015693,GO:0016020,GO:0016323,GO:0019725,GO:0022414,GO:0022857,GO:0022890,GO:0030001,GO:0030425,GO:0031214,GO:0032026,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034505,GO:0035262,GO:0035725,GO:0036477,GO:0040008,GO:0040014,GO:0040018,GO:0040026,GO:0040028,GO:0042221,GO:0042475,GO:0042476,GO:0042592,GO:0042995,GO:0043005,GO:0043025,GO:0043900,GO:0043902,GO:0044297,GO:0044425,GO:0044459,GO:0044463,GO:0044464,GO:0045137,GO:0045927,GO:0046873,GO:0048513,GO:0048518,GO:0048580,GO:0048582,GO:0048608,GO:0048638,GO:0048639,GO:0048646,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050793,GO:0050801,GO:0050896,GO:0051094,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0055065,GO:0055080,GO:0055082,GO:0055085,GO:0061062,GO:0061063,GO:0061458,GO:0065007,GO:0065008,GO:0070166,GO:0070838,GO:0071944,GO:0072507,GO:0072511,GO:0080154,GO:0097186,GO:0097447,GO:0097458,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0120025,GO:0120038,GO:1903830,GO:1905516,GO:2000026,GO:2000241,GO:2000243	-	ko:K16302	-	-	-	-	ko00000,ko02000	9.A.40.3	-	-	CBS,DUF21
SRR25158343_k127_1705170_0	1151119.KB895499_gene3702	1.151e-160	515.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,1W82N@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158343_k127_1705170_4	240015.ACP_0938	8.409e-21	93.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158343_k127_1716427_3	195522.BD01_1611	1.148e-16	93.0	COG1041@1|root,arCOG00047@2157|Archaea,2Y2EJ@28890|Euryarchaeota,2432J@183968|Thermococci	183968|Thermococci	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
SRR25158343_k127_1716427_4	706587.Desti_0403	1.992e-15	79.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MQKU@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158343_k127_1716427_2	685778.AORL01000010_gene3119	1.826e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2K0QB@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1716427_0	469381.Dpep_0215	2.131e-163	530.0	COG0504@1|root,COG0504@2|Bacteria,3TAA0@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158343_k127_1716427_1	1528098.NOVO_03930	1.222e-30	126.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,47F3J@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158343_k127_171761_6	635013.TherJR_0295	1.045e-42	158.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158343_k127_171761_15	1121481.AUAS01000007_gene1113	0.0002075	48.0	COG4980@1|root,COG4980@2|Bacteria,4PDZN@976|Bacteroidetes,47SP7@768503|Cytophagia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR25158343_k127_171761_4	1403948.Q618_VCMC00001G1349	5.616e-46	173.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4D3CD@85005|Actinomycetales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158343_k127_171761_5	1089553.Tph_c25840	1.177e-43	166.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42ERX@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158343_k127_171761_12	1123400.KB904817_gene1465	6.174e-14	79.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,4616H@72273|Thiotrichales	72273|Thiotrichales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158343_k127_171761_0	1347368.HG964409_gene7350	5.226e-90	304.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,1ZCQP@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158343_k127_171761_7	1123037.AUDE01000009_gene1351	2.881e-33	130.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158343_k127_171761_9	1125863.JAFN01000001_gene3300	5.046e-25	109.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158343_k127_171761_1	1423758.BN55_06685	1.62e-62	221.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158343_k127_171761_2	635013.TherJR_0303	2.693e-53	191.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,261KH@186807|Peptococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158343_k127_171761_14	944481.JAFP01000001_gene1471	6.439e-08	56.0	COG0255@1|root,COG0255@2|Bacteria,1Q8ZW@1224|Proteobacteria,439UP@68525|delta/epsilon subdivisions,2X58C@28221|Deltaproteobacteria,2M7GU@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal L29 protein	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158343_k127_171761_11	658659.HMPREF0983_02737	6.256e-18	87.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,3VR8U@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158343_k127_171761_3	441768.ACL_0097	8.215e-52	186.0	COG0093@1|root,COG0093@2|Bacteria,3WTN8@544448|Tenericutes	544448|Tenericutes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158343_k127_171761_8	1122921.KB898209_gene2702	2.831e-25	110.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,26XQC@186822|Paenibacillaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158343_k127_171761_10	1121947.AUHK01000002_gene874	9.566e-21	95.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,22G54@1570339|Peptoniphilaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158343_k127_1742969_0	748449.Halha_2603	6.077e-113	374.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WANE@53433|Halanaerobiales	186801|Clostridia	L	Replicative DNA helicase	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158343_k127_1742969_4	292563.Cyast_1391	0.0006789	51.0	COG1807@1|root,COG1807@2|Bacteria,1G424@1117|Cyanobacteria	1117|Cyanobacteria	M	glycosyl transferase, family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_1742969_3	411463.EUBVEN_01999	3.042e-10	64.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,25WJP@186806|Eubacteriaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158343_k127_1742969_1	926569.ANT_01360	7.557e-56	201.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158343_k127_1742969_2	383372.Rcas_1129	3.727e-11	70.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi,375GR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_1746181_1	1245471.PCA10_27280	7.375e-10	65.0	COG1846@1|root,COG1846@2|Bacteria,1N19E@1224|Proteobacteria,1SECU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	MarR family transcriptional regulator	slyA	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	HTH_27,MarR,MarR_2
SRR25158343_k127_1746181_0	345341.KUTG_02224	3.649e-20	96.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,4EEXI@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158343_k127_1797063_2	1207063.P24_17558	5.07e-40	167.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,2JW58@204441|Rhodospirillales	204441|Rhodospirillales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
SRR25158343_k127_1797063_1	861299.J421_6025	1.759e-44	171.0	COG0730@1|root,COG0730@2|Bacteria,1ZTJT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158343_k127_1797063_3	478741.JAFS01000002_gene625	1.216e-33	141.0	COG0037@1|root,COG0037@2|Bacteria,46T0B@74201|Verrucomicrobia,37GHM@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158343_k127_1797063_0	525904.Tter_1052	3.542e-165	534.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158343_k127_1827887_1	383372.Rcas_1597	0.0	1060.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,374SV@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158343_k127_1827887_0	1293054.HSACCH_00912	0.0	1159.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WAFZ@53433|Halanaerobiales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158343_k127_1857049_6	289376.THEYE_A1193	2.48e-23	107.0	COG0691@1|root,COG0691@2|Bacteria,3J0Q4@40117|Nitrospirae	40117|Nitrospirae	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158343_k127_1857049_4	272134.KB731324_gene3782	2.466e-26	120.0	2EWB1@1|root,33PPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158343_k127_1857049_0	269800.Tfu_1742	2.371e-43	169.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1857049_2	357808.RoseRS_0371	2.056e-29	124.0	COG1525@1|root,COG1525@2|Bacteria,2G964@200795|Chloroflexi,377C3@32061|Chloroflexia	32061|Chloroflexia	L	PFAM nuclease (SNase domain protein)	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158343_k127_1857049_9	870967.VIS19158_16411	0.0003717	49.0	COG0645@1|root,COG0645@2|Bacteria,1RHF4@1224|Proteobacteria,1S3QW@1236|Gammaproteobacteria,1XXP6@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158343_k127_1857049_3	1120985.AUMI01000011_gene415	3.316e-29	123.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,4H48E@909932|Negativicutes	909932|Negativicutes	H	cob(I)yrinic acid a,c-diamide adenosyltransferase	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158343_k127_1857049_7	926550.CLDAP_31160	1.249e-17	85.0	COG0695@1|root,COG0695@2|Bacteria,2G706@200795|Chloroflexi	200795|Chloroflexi	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158343_k127_1857049_5	794903.OPIT5_11690	7.349e-26	117.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia,3K7XV@414999|Opitutae	414999|Opitutae	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158343_k127_1857049_8	1500897.JQNA01000002_gene2125	0.0002263	45.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,1K8CZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158343_k127_1865456_11	926550.CLDAP_28630	1.526e-63	223.0	COG0044@1|root,COG0044@2|Bacteria,2G640@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158343_k127_1865456_6	682795.AciX8_0552	1.601e-101	342.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	pyrD	-	1.3.1.14	ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,DHO_dh,NAD_binding_1
SRR25158343_k127_1865456_10	690850.Desaf_0114	4.922e-64	230.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MXZ@68525|delta/epsilon subdivisions,2WJWG@28221|Deltaproteobacteria,2MANP@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158343_k127_1865456_8	1121403.AUCV01000046_gene1117	7.04e-89	301.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,42Z8V@68525|delta/epsilon subdivisions,2WUJD@28221|Deltaproteobacteria,2MMN7@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158343_k127_1865456_13	3880.AET02272	7.026e-47	175.0	COG0461@1|root,KOG1377@2759|Eukaryota,37INB@33090|Viridiplantae,3GBYY@35493|Streptophyta,4JNNC@91835|fabids	35493|Streptophyta	F	Uridine 5-monophosphate	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016036,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0051716,GO:0071496	2.4.2.10,4.1.1.23	ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
SRR25158343_k127_1865456_0	1121935.AQXX01000092_gene3370	0.0	1548.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XH4B@135619|Oceanospirillales	135619|Oceanospirillales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
SRR25158343_k127_1865456_3	1123487.KB892865_gene1515	1.404e-124	410.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,2KVM3@206389|Rhodocyclales	206389|Rhodocyclales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158343_k127_1865456_17	653386.HMPREF0975_01127	3.194e-25	110.0	2BPN1@1|root,32IF3@2|Bacteria,2HM7R@201174|Actinobacteria,4D6HS@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1865456_20	349161.Dred_1227	1.635e-07	57.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,24BRP@186801|Clostridia,264ZG@186807|Peptococcaceae	186801|Clostridia	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
SRR25158343_k127_1865456_2	1183438.GKIL_3787	6.919e-132	438.0	COG0034@1|root,COG0034@2|Bacteria,1G1C9@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158343_k127_1865456_18	682795.AciX8_3637	5.388e-18	93.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158343_k127_1865456_1	1121430.JMLG01000005_gene779	2.545e-135	443.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158343_k127_1865456_14	1131462.DCF50_p2001	1.082e-31	129.0	COG1878@1|root,COG1878@2|Bacteria,1UFUJ@1239|Firmicutes,24HGD@186801|Clostridia,2670B@186807|Peptococcaceae	186801|Clostridia	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158343_k127_1865456_12	186497.PF0427	1.446e-49	181.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,24415@183968|Thermococci	183968|Thermococci	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158343_k127_1865456_7	485913.Krac_12629	1.819e-101	342.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158343_k127_1865456_4	742766.HMPREF9455_03265	7.09e-124	407.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,2FPKZ@200643|Bacteroidia,22WD6@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158343_k127_1865456_5	748449.Halha_2587	7.245e-122	406.0	COG0015@1|root,COG0015@2|Bacteria,1V12Z@1239|Firmicutes,249QU@186801|Clostridia,3WA99@53433|Halanaerobiales	186801|Clostridia	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
SRR25158343_k127_1865456_9	929712.KI912613_gene210	4.847e-82	293.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CPP3@84995|Rubrobacteria	2|Bacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158343_k127_1865456_16	589865.DaAHT2_0500	1.205e-26	126.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WMW3@28221|Deltaproteobacteria,2MPF8@213118|Desulfobacterales	28221|Deltaproteobacteria	F	MGS-like domain	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158343_k127_1865456_19	1246995.AFR_25920	1.446e-11	74.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DH3D@85008|Micromonosporales	201174|Actinobacteria	T	Signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
SRR25158343_k127_1865456_15	1121324.CLIT_10c02230	7.667e-27	117.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25QT4@186804|Peptostreptococcaceae	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
SRR25158343_k127_192307_2	110663.KI911558_gene2285	3.918e-18	88.0	COG0465@1|root,COG0465@2|Bacteria,1G1BT@1117|Cyanobacteria,1GYE1@1129|Synechococcus	1117|Cyanobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH2	GO:0003674,GO:0003824,GO:0004176,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0010206,GO:0010304,GO:0015979,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031323,GO:0031324,GO:0042548,GO:0042623,GO:0043155,GO:0043170,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158343_k127_192307_1	1449126.JQKL01000018_gene3286	5.301e-45	182.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,26BKG@186813|unclassified Clostridiales	186801|Clostridia	S	MviN-like protein	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158343_k127_192307_0	1089552.KI911559_gene1506	3.192e-200	639.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2JPAT@204441|Rhodospirillales	204441|Rhodospirillales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158343_k127_1954906_1	762903.Pedsa_0767	5.275e-57	218.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158343_k127_1954906_3	1280390.CBQR020000171_gene4569	1.828e-31	132.0	COG4330@1|root,COG4330@2|Bacteria,1VEKF@1239|Firmicutes,4HPYW@91061|Bacilli,26RZG@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
SRR25158343_k127_1954906_4	378806.STAUR_4024	2.016e-26	113.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_1954906_2	1379698.RBG1_1C00001G1620	1.594e-54	204.0	COG2222@1|root,COG2222@2|Bacteria,2NQVV@2323|unclassified Bacteria	2|Bacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	pgi	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRR25158343_k127_1954906_0	926550.CLDAP_06600	1.863e-162	528.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158343_k127_1954906_5	1120951.AUBG01000012_gene1641	9.883e-19	88.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158343_k127_1977930_2	1268635.Loa_02615	1.457e-14	76.0	2APF2@1|root,31EHR@2|Bacteria,1Q4KW@1224|Proteobacteria,1TD9F@1236|Gammaproteobacteria,1JGG8@118969|Legionellales	118969|Legionellales	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158343_k127_1977930_3	1449058.JQKT01000015_gene2243	2.068e-05	48.0	2DS51@1|root,33EJB@2|Bacteria,2IM77@201174|Actinobacteria,4FPD7@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158343_k127_1977930_0	1134474.O59_002865	3.33e-126	410.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMC9@1236|Gammaproteobacteria,1FI8N@10|Cellvibrio	1236|Gammaproteobacteria	IQ	KR domain	yghA	GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_1977930_1	106370.Francci3_4459	1.044e-114	375.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4ERRU@85013|Frankiales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158343_k127_1992213_0	2325.TKV_c11760	4.234e-130	436.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158343_k127_199276_1	266809.PM03_04285	3.641e-05	51.0	COG0355@1|root,COG0355@2|Bacteria,1RKXG@1224|Proteobacteria,2VGWU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC_1	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158343_k127_199276_0	1207055.C100_03990	4.765e-14	74.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,2K03H@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158343_k127_2011604_1	1336243.JAEA01000007_gene823	7.967e-35	136.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,1JUVH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158343_k127_2011604_2	1273125.Rrhod_2586	7.518e-29	125.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4FX7S@85025|Nocardiaceae	201174|Actinobacteria	GL	Reverse transcriptase-like	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR25158343_k127_2011604_3	743722.Sph21_2825	2.747e-20	100.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1ITUM@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158343_k127_2011604_4	768710.DesyoDRAFT_0438	1.334e-17	87.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
SRR25158343_k127_2011604_0	58123.JOFJ01000025_gene3397	1.538e-50	187.0	COG2227@1|root,COG2227@2|Bacteria,2IPIT@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2015244_11	694427.Palpr_1089	4.501e-16	94.0	COG2911@1|root,COG4675@1|root,COG5295@1|root,COG2911@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	sraP	-	-	ko:K15125,ko:K18491,ko:K20276,ko:K21449	ko02024,ko04550,ko05133,map02024,map04550,map05133	-	-	-	ko00000,ko00001,ko00536,ko02000,ko03000	1.B.40.2	-	-	Gram_pos_anchor
SRR25158343_k127_2015244_10	553385.JEMF01000022_gene3207	5.034e-17	84.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1XJZI@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158343_k127_2015244_1	1216932.CM240_0517	1.66e-209	685.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,36DSA@31979|Clostridiaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158343_k127_2015244_2	469383.Cwoe_3559	5.25e-171	551.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CP5R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158343_k127_2015244_0	1121877.JQKF01000002_gene1700	0.0	1092.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158343_k127_2015244_7	1131462.DCF50_p1721	1.72e-44	166.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,261UI@186807|Peptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158343_k127_2015244_3	867903.ThesuDRAFT_01657	2.459e-120	401.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WCEE@538999|Clostridiales incertae sedis	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158343_k127_2015244_5	555088.DealDRAFT_1342	8.813e-80	280.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,24948@186801|Clostridia,42JJ6@68298|Syntrophomonadaceae	186801|Clostridia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158343_k127_2015244_6	243164.DET0496	1.182e-68	241.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi,34CJJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158343_k127_2015244_8	1122973.KB904290_gene407	5.7e-23	107.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,2FM8T@200643|Bacteroidia,22XNF@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
SRR25158343_k127_2015244_9	203124.Tery_0596	7.225e-23	104.0	COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,1HB1I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158343_k127_2015244_12	232721.Ajs_2615	1.777e-07	56.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2VQYD@28216|Betaproteobacteria,4AE74@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158343_k127_2015244_4	1121430.JMLG01000006_gene1735	5.629e-114	391.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25ZXM@186807|Peptococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158343_k127_2016939_0	667014.Thein_0156	7.112e-162	527.0	COG0272@1|root,COG0272@2|Bacteria,2GGUH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158343_k127_2016939_1	1001240.GY21_02600	6.597e-99	331.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FMKM@85023|Microbacteriaceae	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158343_k127_2016939_2	1121952.ATXT01000014_gene1505	1.779e-58	208.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4FK45@85023|Microbacteriaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158343_k127_2068043_3	525904.Tter_0795	4.257e-52	191.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158343_k127_2068043_2	1121289.JHVL01000005_gene1004	1.096e-127	434.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158343_k127_2068043_6	1380390.JIAT01000009_gene1313	1.536e-35	153.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CBM_6,Cellulase,DUF1573,DUF4978,F5_F8_type_C,Laminin_G_3,Pectate_lyase_3,RicinB_lectin_2
SRR25158343_k127_2068043_0	718252.FP2_24270	5.473e-149	497.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158343_k127_2068043_8	485913.Krac_12484	9.765e-15	80.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158343_k127_2068043_7	767817.Desgi_4747	7.382e-29	122.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,261VY@186807|Peptococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158343_k127_2068043_11	1121104.AQXH01000001_gene1515	1.443e-10	63.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158343_k127_2068043_12	760192.Halhy_3737	2.139e-09	63.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1ITMS@117747|Sphingobacteriia	976|Bacteroidetes	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158343_k127_2068043_5	717231.Flexsi_1822	1.715e-47	176.0	COG0231@1|root,COG0231@2|Bacteria,2GEJZ@200930|Deferribacteres	200930|Deferribacteres	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158343_k127_2068043_4	760142.Hipma_1448	8.338e-50	185.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2M71I@213113|Desulfurellales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158343_k127_2068043_9	67332.FM21_30585	6.439e-14	81.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158343_k127_2068043_10	479434.Sthe_3401	1.732e-12	76.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_2068043_13	1450525.JATV01000009_gene775	1.277e-06	60.0	2DF54@1|root,32U4N@2|Bacteria,4NWS7@976|Bacteroidetes,1I9NX@117743|Flavobacteriia	976|Bacteroidetes	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_3
SRR25158343_k127_2068043_1	446462.Amir_0736	4.546e-139	451.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4DYTA@85010|Pseudonocardiales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158343_k127_2076637_5	710696.Intca_0277	1.086e-18	88.0	COG1669@1|root,COG1669@2|Bacteria,2GXGT@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158343_k127_2076637_4	762948.HMPREF0733_10760	7.344e-23	101.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158343_k127_2076637_7	1144664.F973_02519	9.226e-08	61.0	COG0457@1|root,COG0457@2|Bacteria,1QY6N@1224|Proteobacteria,1T4SY@1236|Gammaproteobacteria,3NQ0F@468|Moraxellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C,TPR_14,Tcf25
SRR25158343_k127_2076637_8	421072.IO89_12605	4.18e-07	53.0	2EIK5@1|root,33CBF@2|Bacteria,4NV2P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2076637_9	1173024.KI912151_gene2063	6.424e-05	50.0	COG5502@1|root,COG5502@2|Bacteria,1GA7I@1117|Cyanobacteria,1JKYT@1189|Stigonemataceae	1117|Cyanobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158343_k127_2076637_6	1123023.JIAI01000012_gene9160	8.849e-17	94.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158343_k127_2076637_1	1161401.ASJA01000003_gene2981	5.204e-57	207.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,43W4Q@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein	MA20_17930	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158343_k127_2076637_2	643648.Slip_0741	9.106e-47	173.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,42JYC@68298|Syntrophomonadaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158343_k127_2076637_3	1282887.AUJG01000013_gene2526	7.81e-33	134.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158343_k127_2076637_0	1401067.HMPREF0872_01200	8.43e-134	434.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4H1YW@909932|Negativicutes	909932|Negativicutes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158343_k127_2077289_2	1193181.BN10_1300016	5.009e-17	87.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2077289_1	1382306.JNIM01000001_gene2347	1.075e-17	92.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158343_k127_2077289_0	309801.trd_0652	7.156e-282	888.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,27Y2U@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158343_k127_2078773_0	351627.Csac_0660	5.977e-73	253.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,42G06@68295|Thermoanaerobacterales	186801|Clostridia	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_2086032_3	1179773.BN6_60160	7.487e-05	55.0	COG1361@1|root,COG2373@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
SRR25158343_k127_2086032_0	1047013.AQSP01000118_gene1252	1.07e-98	356.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2086032_2	1437608.BBIA_0164	4.469e-12	78.0	COG0366@1|root,COG1523@1|root,COG3757@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,COG3757@2|Bacteria,2GKK1@201174|Actinobacteria,4D2UY@85004|Bifidobacteriales	201174|Actinobacteria	M	Aamy_C	-	-	3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	-	R02108,R02111,R02112,R11262	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,Big_4,CBM_25,CBM_48,DUF5011,PUD
SRR25158343_k127_2086032_1	1000569.HMPREF1040_1009	1.703e-76	267.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,4H1VZ@909932|Negativicutes	909932|Negativicutes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158343_k127_211314_0	1121896.JMLU01000002_gene338	1.78e-20	107.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2NSTD@237|Flavobacterium	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158343_k127_2156532_5	304371.MCP_1758	4.768e-47	177.0	COG0715@1|root,arCOG01803@2157|Archaea	2157|Archaea	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	Lipoprotein_9,NMT1,NMT1_2,TctC
SRR25158343_k127_2156532_6	316274.Haur_4061	1.289e-36	155.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158343_k127_2156532_2	1266914.ATUK01000001_gene770	3.191e-70	244.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158343_k127_2156532_3	1068978.AMETH_1798	5.932e-68	241.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DZTI@85010|Pseudonocardiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158343_k127_2156532_1	477641.MODMU_0989	2.124e-102	342.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_2156532_8	105425.BBPL01000009_gene1397	7.951e-28	124.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,2NK05@228398|Streptacidiphilus	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158343_k127_2156532_7	1320556.AVBP01000004_gene3674	5.075e-31	134.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158343_k127_2156532_4	1128421.JAGA01000002_gene901	5.661e-62	225.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
SRR25158343_k127_2156532_0	1123368.AUIS01000018_gene726	1.096e-200	632.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,2NBU1@225057|Acidithiobacillales	225057|Acidithiobacillales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158343_k127_2193761_5	395964.KE386496_gene765	3.206e-12	76.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2TRGG@28211|Alphaproteobacteria,3N9NM@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Major intrinsic protein	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158343_k127_2193761_1	1122605.KB893644_gene1305	3.039e-96	353.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158343_k127_2193761_4	1382304.JNIL01000001_gene921	5.356e-42	170.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,2791J@186823|Alicyclobacillaceae	91061|Bacilli	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DoxX,Pyr_redox_2
SRR25158343_k127_2193761_0	561175.KB894093_gene3114	1.693e-104	351.0	COG0438@1|root,COG0438@2|Bacteria,2GX8V@201174|Actinobacteria,4EG9S@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2193761_2	634497.HAH_2779	3.028e-66	246.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota,23SCM@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	glcD2	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
SRR25158343_k127_2193761_3	1229780.BN381_60038	1.573e-61	224.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,3UWQP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Polyprenyl synthetase	-	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158343_k127_237658_5	391623.TERMP_01883	0.0004763	51.0	COG0063@1|root,arCOG00018@2157|Archaea,2XU4W@28890|Euryarchaeota,242WG@183968|Thermococci	183968|Thermococci	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158343_k127_237658_3	748727.CLJU_c21640	1.375e-22	106.0	COG0560@1|root,COG0560@2|Bacteria,1V4PY@1239|Firmicutes,25CGU@186801|Clostridia,36WVR@31979|Clostridiaceae	186801|Clostridia	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158343_k127_237658_4	439481.Aboo_0221	5.965e-15	86.0	COG1073@1|root,arCOG01651@2157|Archaea	439481.Aboo_0221|-	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_237658_0	379066.GAU_3349	5.814e-120	390.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	xth	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158343_k127_237658_2	1392489.JPOL01000002_gene1414	3.616e-72	250.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia,2XI62@283735|Leeuwenhoekiella	976|Bacteroidetes	F	Amino acid kinase family	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158343_k127_237658_1	264732.Moth_0162	1.938e-96	337.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158343_k127_246360_6	237368.SCABRO_03418	3.211e-31	126.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158343_k127_246360_0	1123013.AUIC01000002_gene839	4.309e-166	527.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4FKJH@85023|Microbacteriaceae	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_246360_4	1284679.HMPREF1626_07290	4.31e-76	259.0	COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4D467@85005|Actinomycetales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
SRR25158343_k127_246360_2	408672.NBCG_03451	8.095e-93	313.0	COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4DN84@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
SRR25158343_k127_246360_1	1120965.AUBV01000007_gene2548	2.08e-133	431.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,47JPC@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158343_k127_246360_7	1408254.T458_16075	1.829e-12	80.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli	91061|Bacilli	M	Peptidase, M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,LysM,Peptidase_M23
SRR25158343_k127_246360_5	1210884.HG799465_gene11380	2.361e-51	201.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
SRR25158343_k127_246360_3	1120960.ATXG01000010_gene2655	5.201e-79	280.0	COG0739@1|root,COG5479@1|root,COG5640@1|root,COG0739@2|Bacteria,COG5479@2|Bacteria,COG5640@2|Bacteria,2HYIN@201174|Actinobacteria,4FMC4@85023|Microbacteriaceae	201174|Actinobacteria	M	hydrolase, family 25	wcqK	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LGFP,SH3_3
SRR25158343_k127_294151_7	1122182.KB903833_gene5352	8.922e-06	53.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4D8YM@85008|Micromonosporales	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158343_k127_294151_5	1089545.KB913037_gene7895	1.366e-20	98.0	COG1011@1|root,COG1011@2|Bacteria,2I92U@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158343_k127_294151_1	585501.HMPREF6123_0587	2.787e-163	547.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,2PRS4@265975|Oribacterium	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158343_k127_294151_6	648996.Theam_1206	5.546e-17	87.0	COG0212@1|root,COG0212@2|Bacteria,2G47M@200783|Aquificae	200783|Aquificae	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158343_k127_294151_0	1075090.GOAMR_59_00440	4.68e-219	711.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4GCPV@85026|Gordoniaceae	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158343_k127_294151_3	709991.Odosp_1431	6.724e-41	157.0	COG0237@1|root,COG0237@2|Bacteria	2|Bacteria	H	dephospho-CoA kinase activity	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,3.2.2.23,4.2.99.18	ko:K00859,ko:K08309,ko:K10563	ko00770,ko01100,ko03410,map00770,map01100,map03410	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01011,ko03400	-	GH23	iIT341.HP0831	CoaE
SRR25158343_k127_294151_2	865861.AZSU01000003_gene2059	3.734e-108	362.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,36E45@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_294151_4	255470.cbdbA527	5.17e-25	116.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,34CVJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
SRR25158343_k127_305542_3	2903.EOD35699	3.095e-35	141.0	COG0519@1|root,KOG1622@2759|Eukaryota	2759|Eukaryota	F	GMP synthase (glutamine-hydrolyzing) activity	GMPS	GO:0000902,GO:0000904,GO:0001101,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005700,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006177,GO:0006325,GO:0006464,GO:0006508,GO:0006520,GO:0006541,GO:0006543,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006996,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0008047,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010952,GO:0016043,GO:0016054,GO:0016504,GO:0016569,GO:0016570,GO:0016578,GO:0016579,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0022008,GO:0030030,GO:0030154,GO:0030162,GO:0030182,GO:0030234,GO:0031175,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0035800,GO:0036211,GO:0040011,GO:0042221,GO:0042278,GO:0042330,GO:0042440,GO:0042451,GO:0042455,GO:0042493,GO:0042802,GO:0043085,GO:0043170,GO:0043200,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043436,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046037,GO:0046112,GO:0046128,GO:0046129,GO:0046148,GO:0046390,GO:0046395,GO:0046483,GO:0048468,GO:0048518,GO:0048522,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051276,GO:0051336,GO:0051345,GO:0052547,GO:0055086,GO:0060255,GO:0061134,GO:0061564,GO:0065007,GO:0065009,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097485,GO:0098772,GO:0120036,GO:0120039,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901367,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:2000152,GO:2000158	6.3.5.2	ko:K01951,ko:K04257	ko00230,ko00983,ko01100,ko04740,map00230,map00983,map01100,map04740	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko04030	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158343_k127_305542_0	1267580.AF6_0432	1.285e-270	855.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,21V55@150247|Anoxybacillus	91061|Bacilli	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158343_k127_305542_4	485913.Krac_8246	2.568e-27	118.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158343_k127_305542_5	1329516.JPST01000035_gene3173	2.417e-17	88.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,27C00@186824|Thermoactinomycetaceae	91061|Bacilli	F	NUDIX domain	apfA	-	3.6.1.61	ko:K18445	ko00230,map00230	-	R00184	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158343_k127_305542_2	1158608.I583_02628	8.367e-49	183.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,4B0CI@81852|Enterococcaceae	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158343_k127_305542_7	243272.MARTH_orf245	6.346e-13	75.0	COG0228@1|root,COG0228@2|Bacteria,3WTVG@544448|Tenericutes	544448|Tenericutes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158343_k127_305542_6	768670.Calni_2010	3.721e-15	83.0	COG1837@1|root,COG1837@2|Bacteria,2GFZI@200930|Deferribacteres	200930|Deferribacteres	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158343_k127_305542_1	1430331.EP10_16865	1.799e-63	224.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1WE2C@129337|Geobacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158343_k127_306456_5	926550.CLDAP_17900	4.371e-17	81.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158343_k127_306456_1	1410666.JHXG01000003_gene1235	5.109e-39	149.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158343_k127_306456_4	767817.Desgi_0355	2.764e-20	97.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,261MK@186807|Peptococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158343_k127_306456_0	1313172.YM304_25950	4.905e-114	396.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158343_k127_306456_3	69395.JQLZ01000005_gene3801	8.44e-21	108.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2KGC2@204458|Caulobacterales	204458|Caulobacterales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158343_k127_306456_2	44689.DDB0230132	2.966e-38	152.0	COG0717@1|root,2RDXQ@2759|Eukaryota,3XCUB@554915|Amoebozoa	554915|Amoebozoa	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158343_k127_32462_1	1304880.JAGB01000001_gene514	5.191e-104	368.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR25158343_k127_32462_4	313606.M23134_03579	2.954e-71	253.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158343_k127_32462_7	1283287.KB822575_gene399	2.532e-32	131.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4DQT9@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0234 family	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158343_k127_32462_0	656024.FsymDg_3597	1.559e-116	391.0	COG3408@1|root,COG3408@2|Bacteria,2I3UW@201174|Actinobacteria,4EXFQ@85013|Frankiales	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100,Glyco_hydro_63,Trehalase
SRR25158343_k127_32462_6	1089550.ATTH01000001_gene1481	1.299e-35	147.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1FJ8C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158343_k127_32462_5	880073.Calab_0862	3.48e-44	174.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158343_k127_32462_8	1123258.AQXZ01000018_gene1182	8.863e-24	110.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,PG_binding_4,YkuD
SRR25158343_k127_32462_3	390989.JOEG01000017_gene6236	9.476e-72	250.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria,4DDCM@85008|Micromonosporales	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158343_k127_32462_9	866776.HMPREF9321_1427	1.332e-17	88.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,4H4AY@909932|Negativicutes	909932|Negativicutes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158343_k127_32462_2	656024.FsymDg_3812	1.061e-75	265.0	COG2899@1|root,COG2899@2|Bacteria,2GJNH@201174|Actinobacteria,4ES65@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
SRR25158343_k127_339019_6	224308.BSU25640	4.197e-21	100.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158343_k127_339019_3	491205.JARQ01000007_gene3249	5.923e-39	154.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1I8YG@117743|Flavobacteriia,3ZPI2@59732|Chryseobacterium	976|Bacteroidetes	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158343_k127_339019_7	1122939.ATUD01000007_gene2099	2.047e-06	60.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQYI@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158343_k127_339019_0	649638.Trad_2070	1.035e-101	346.0	COG0017@1|root,COG0017@2|Bacteria,1WJAX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspC	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158343_k127_339019_2	717785.HYPMC_2326	8.55e-40	158.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2TUV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
SRR25158343_k127_339019_5	1403948.Q618_VCMC00001G1260	5.361e-27	117.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4D3PC@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158343_k127_339019_4	1032480.MLP_24610	2.969e-28	117.0	COG1694@1|root,COG1694@2|Bacteria,2INKJ@201174|Actinobacteria,4DRIK@85009|Propionibacteriales	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158343_k127_339019_1	1280696.ATVY01000066_gene2457	4.042e-81	283.0	COG0773@1|root,COG0773@2|Bacteria,1VTVI@1239|Firmicutes,24Y9A@186801|Clostridia,4C1ZN@830|Butyrivibrio	186801|Clostridia	M	Mur ligase family, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_339445_2	237368.SCABRO_00076	1.934e-06	57.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158343_k127_339445_1	935948.KE386495_gene1924	6.832e-10	71.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,42FXJ@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM O-antigen polymerase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRR25158343_k127_339445_3	1304876.AZVC01000001_gene1600	0.0005305	48.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158343_k127_339445_0	1340493.JNIF01000003_gene1795	1.254e-11	71.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria	57723|Acidobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158343_k127_389855_4	1907.SGLAU_07580	8.661e-17	96.0	COG2755@1|root,COG2755@2|Bacteria,2GRDF@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	GO:0003674,GO:0003824,GO:0004806,GO:0005575,GO:0005576,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019433,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046461,GO:0046464,GO:0046486,GO:0046503,GO:0052689,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_389855_3	1121011.AUCB01000055_gene3462	1.091e-28	121.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1I1YY@117743|Flavobacteriia,23HBX@178469|Arenibacter	976|Bacteroidetes	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158343_k127_389855_6	1236902.ANAS01000004_gene3496	0.0001072	53.0	COG1426@1|root,COG1426@2|Bacteria,2IQH6@201174|Actinobacteria	201174|Actinobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158343_k127_389855_5	717606.PaecuDRAFT_1133	3.39e-05	55.0	COG1011@1|root,COG1011@2|Bacteria,1VCB5@1239|Firmicutes,4HM48@91061|Bacilli,26YDC@186822|Paenibacillaceae	91061|Bacilli	S	Hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158343_k127_389855_0	1382306.JNIM01000001_gene3603	4.726e-192	630.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158343_k127_389855_1	485913.Krac_10956	4.586e-96	328.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158343_k127_389855_2	1449126.JQKL01000021_gene73	1.638e-44	171.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,267UW@186813|unclassified Clostridiales	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_448726_3	1203556.HMPREF1478_01795	3.576e-117	386.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D318@85005|Actinomycetales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158343_k127_448726_7	1408473.JHXO01000005_gene1669	2.44e-35	141.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158343_k127_448726_10	1089547.KB913013_gene583	2.256e-21	102.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,47N3P@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158343_k127_448726_4	1121924.ATWH01000014_gene3392	1.087e-102	343.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria,4FN7S@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158343_k127_448726_2	1121924.ATWH01000014_gene3393	1.728e-126	413.0	COG3958@1|root,COG3958@2|Bacteria,2I8VM@201174|Actinobacteria,4FKW5@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158343_k127_448726_6	1321778.HMPREF1982_00271	6.376e-37	151.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,268GH@186813|unclassified Clostridiales	186801|Clostridia	G	Fructose-bisphosphate aldolase class-II	gatY	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158343_k127_448726_8	349521.HCH_06817	2.731e-34	144.0	COG0524@1|root,COG0524@2|Bacteria,1QTMT@1224|Proteobacteria,1S1JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158343_k127_448726_9	314345.SPV1_10621	1.111e-28	123.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
SRR25158343_k127_448726_0	479434.Sthe_0796	6.347e-263	824.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158343_k127_448726_11	221360.RS9917_03658	3.768e-14	75.0	COG0721@1|root,COG0721@2|Bacteria,1G7N8@1117|Cyanobacteria,1H0W2@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158343_k127_448726_1	445973.CLOBAR_01756	1.881e-135	445.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,25QZW@186804|Peptostreptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158343_k127_448726_5	521098.Aaci_0689	1.539e-50	184.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,2780K@186823|Alicyclobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158343_k127_480161_5	1128421.JAGA01000003_gene3013	4.387e-33	133.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158343_k127_480161_1	716544.wcw_0344	1.141e-127	417.0	COG0458@1|root,COG0505@1|root,COG0458@2|Bacteria,COG0505@2|Bacteria,2JGMC@204428|Chlamydiae	204428|Chlamydiae	F	Carbamoylphosphate synthase large subunit (split gene in MJ)	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158343_k127_480161_0	716544.wcw_0344	0.0	1358.0	COG0458@1|root,COG0505@1|root,COG0458@2|Bacteria,COG0505@2|Bacteria,2JGMC@204428|Chlamydiae	204428|Chlamydiae	F	Carbamoylphosphate synthase large subunit (split gene in MJ)	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158343_k127_480161_4	682795.AciX8_0556	3.836e-86	295.0	COG0540@1|root,COG0540@2|Bacteria,3Y7K1@57723|Acidobacteria,2JMQX@204432|Acidobacteriia	204432|Acidobacteriia	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158343_k127_480161_2	1121877.JQKF01000008_gene656	4.766e-107	355.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CMVQ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158343_k127_480161_3	632335.Calkr_2479	1.775e-87	306.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,42FKX@68295|Thermoanaerobacterales	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158343_k127_549728_2	887898.HMPREF0551_1929	0.0007236	47.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,2VUEX@28216|Betaproteobacteria,1KFPG@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158343_k127_549728_0	868595.Desca_0199	1.57e-64	225.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,260QW@186807|Peptococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158343_k127_549728_1	760142.Hipma_1388	6.566e-35	138.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2WNAH@28221|Deltaproteobacteria,2M75Q@213113|Desulfurellales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158343_k127_562799_2	525256.HMPREF0091_10056	5.937e-23	108.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CU8U@84998|Coriobacteriia	84998|Coriobacteriia	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158343_k127_562799_1	1449976.KALB_4695	8.335e-24	114.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	cbpD	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHAP,CW_binding_1,GBS_Bsp-like,SH3_5
SRR25158343_k127_562799_0	935837.JAEK01000017_gene1349	7.973e-41	160.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
SRR25158343_k127_603956_0	762948.HMPREF0733_10457	2.658e-118	388.0	COG1054@1|root,COG1054@2|Bacteria,2GMMP@201174|Actinobacteria,1W8JF@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
SRR25158343_k127_603956_1	574087.Acear_0289	1.281e-96	334.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WAG5@53433|Halanaerobiales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158343_k127_603956_3	1122176.KB903535_gene1900	1.898e-67	245.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPMC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158343_k127_603956_8	706587.Desti_1113	2.453e-09	63.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42WCF@68525|delta/epsilon subdivisions,2WRES@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158343_k127_603956_5	309801.trd_0782	1.156e-50	201.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158343_k127_603956_2	768670.Calni_1838	6.999e-74	269.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GEXA@200930|Deferribacteres	200930|Deferribacteres	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
SRR25158343_k127_603956_7	89187.ISM_04185	9.194e-13	74.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,2U5W7@28211|Alphaproteobacteria,46NDA@74030|Roseovarius	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158343_k127_603956_6	314254.OA2633_05091	5.535e-20	100.0	COG2105@1|root,COG2105@2|Bacteria,1NIAM@1224|Proteobacteria,2UG92@28211|Alphaproteobacteria,43YGW@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158343_k127_603956_4	521098.Aaci_0345	8.831e-59	219.0	COG1686@1|root,COG1686@2|Bacteria,1VZJP@1239|Firmicutes	1239|Firmicutes	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR25158343_k127_689844_6	338963.Pcar_1695	5.295e-08	57.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
SRR25158343_k127_689844_0	204536.SULAZ_1250	3.558e-122	407.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,2G3J0@200783|Aquificae	200783|Aquificae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158343_k127_689844_1	1210884.HG799463_gene10314	4.003e-96	329.0	COG1626@1|root,COG1626@2|Bacteria,2J1CN@203682|Planctomycetes	203682|Planctomycetes	G	Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
SRR25158343_k127_689844_4	983917.RGE_46940	1.255e-30	123.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158343_k127_689844_5	215803.DB30_6445	3.119e-25	114.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,434GM@68525|delta/epsilon subdivisions,2WYTZ@28221|Deltaproteobacteria,2Z0M0@29|Myxococcales	28221|Deltaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
SRR25158343_k127_689844_8	235985.BBPN01000022_gene2543	6.285e-05	51.0	COG1846@1|root,COG1846@2|Bacteria,2INHB@201174|Actinobacteria,2NJ66@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	HTH_27,MarR
SRR25158343_k127_689844_3	311424.DhcVS_347	2.77e-55	203.0	COG0030@1|root,COG0030@2|Bacteria,2G6ER@200795|Chloroflexi,34CIF@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158343_k127_689844_7	327277.JHAL01000002_gene1173	4.628e-07	62.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
SRR25158343_k127_689844_2	1074451.CRL705_688	2.508e-88	304.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158343_k127_705428_4	1236976.JCM16418_991	1.178e-05	51.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,26QUX@186822|Paenibacillaceae	91061|Bacilli	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158343_k127_705428_2	457421.CBFG_00464	9.509e-25	109.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,269HT@186813|unclassified Clostridiales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158343_k127_705428_0	1382359.JIAL01000001_gene895	2.2e-240	758.0	COG0443@1|root,COG0443@2|Bacteria,3Y2XU@57723|Acidobacteria,2JHT1@204432|Acidobacteriia	204432|Acidobacteriia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158343_k127_705428_1	635013.TherJR_2449	1.285e-100	339.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158343_k127_705428_3	980584.AFPB01000163_gene2281	2.708e-07	61.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1HZSJ@117743|Flavobacteriia	976|Bacteroidetes	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
SRR25158343_k127_713980_5	742725.HMPREF9450_00703	1.329e-10	64.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,2FSN9@200643|Bacteroidia,22UMY@171550|Rikenellaceae	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158343_k127_713980_1	395494.Galf_1779	2.989e-43	164.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,44VRD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158343_k127_713980_2	1321814.HMPREF9089_01268	3.409e-26	115.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158343_k127_713980_4	378806.STAUR_7113	2.236e-16	87.0	COG0642@1|root,COG2205@2|Bacteria,1QX4R@1224|Proteobacteria,4301I@68525|delta/epsilon subdivisions,2WVE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MEDS
SRR25158343_k127_713980_0	1249627.D779_0867	5.926e-72	263.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158343_k127_713980_3	43354.JOIJ01000006_gene1884	1.574e-22	100.0	COG0566@1|root,COG0566@2|Bacteria,2HRZ2@201174|Actinobacteria,4EBF4@85010|Pseudonocardiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158343_k127_791535_0	2340.JV46_15070	4.71e-67	239.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1J5AE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158343_k127_791535_1	608506.COB47_1628	1.463e-55	203.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158343_k127_791535_3	522772.Dacet_0496	2.782e-42	161.0	COG0233@1|root,COG0233@2|Bacteria,2GFEE@200930|Deferribacteres	200930|Deferribacteres	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158343_k127_791535_4	1451261.AS96_14640	2.113e-27	125.0	COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4FPN8@85023|Microbacteriaceae	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158343_k127_791535_2	525904.Tter_1705	2.787e-45	179.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.4.21.107	ko:K04771,ko:K11749,ko:K16922	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158343_k127_7925_2	1321774.HMPREF9108_00274	6.019e-06	58.0	COG0568@1|root,COG0568@2|Bacteria,378VX@32066|Fusobacteria	32066|Fusobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_7925_0	1189612.A33Q_1338	4.225e-257	813.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158343_k127_7925_1	394503.Ccel_2057	1.102e-54	202.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,36EJZ@31979|Clostridiaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158343_k127_805184_0	469383.Cwoe_2887	3.845e-104	349.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CQZ9@84995|Rubrobacteria	84995|Rubrobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158343_k127_805184_2	670292.JH26_05880	3.633e-48	176.0	297W1@1|root,2ZV2M@2|Bacteria,1QN4J@1224|Proteobacteria,2U80H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158343_k127_805184_1	873447.SPB_0898	6.318e-57	206.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158343_k127_808948_22	342949.PNA2_1283	8.558e-05	47.0	COG1794@1|root,arCOG02006@2157|Archaea,2XYRI@28890|Euryarchaeota,243N8@183968|Thermococci	183968|Thermococci	M	Asp/Glu/Hydantoin racemase	racD-1	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158343_k127_808948_12	293826.Amet_3620	8.998e-22	102.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,36KFN@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158343_k127_808948_24	596324.TREVI0001_1776	0.0003157	46.0	COG3041@1|root,COG3041@2|Bacteria,2J8T3@203691|Spirochaetes	203691|Spirochaetes	S	Addiction module toxin, RelE StbE	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
SRR25158343_k127_808948_8	429009.Adeg_1564	2.836e-53	202.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,42F8I@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158343_k127_808948_5	1395587.P364_0101545	1.781e-59	223.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26S7H@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158343_k127_808948_7	309801.trd_0060	1.749e-57	213.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158343_k127_808948_4	767817.Desgi_3664	4.173e-67	250.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,260BS@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158343_k127_808948_3	1128427.KB904821_gene2097	6.323e-68	242.0	COG0275@1|root,COG0275@2|Bacteria,1G0AR@1117|Cyanobacteria,1H8QI@1150|Oscillatoriales	1117|Cyanobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158343_k127_808948_18	1385518.N798_09125	1.04e-13	76.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4FGK3@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158343_k127_808948_13	1032480.MLP_52170	1.051e-20	100.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4DV40@85009|Propionibacteriales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158343_k127_808948_2	1206737.BAGF01000027_gene1478	2.141e-113	370.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria,4FTXE@85025|Nocardiaceae	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158343_k127_808948_9	296591.Bpro_1367	2.529e-31	128.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2VV8S@28216|Betaproteobacteria,4AHZ3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158343_k127_808948_23	1158607.UAU_01847	0.0001065	51.0	COG0681@1|root,COG0681@2|Bacteria,1VH6F@1239|Firmicutes,4HJZA@91061|Bacilli,4B6IN@81852|Enterococcaceae	91061|Bacilli	U	Peptidase S24-like	sipW	GO:0003674,GO:0003824,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158343_k127_808948_0	1121877.JQKF01000045_gene1204	2.637e-154	502.0	COG0210@1|root,COG0507@1|root,COG0210@2|Bacteria,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD2	-	3.6.4.12	ko:K03657,ko:K15255	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032,ko03400	-	-	-	AAA_11,AAA_12,AAA_19,HTH_40,PIF1,PLDc_2,UvrD-helicase,UvrD_C,UvrD_C_2
SRR25158343_k127_808948_15	316274.Haur_2887	2.748e-17	88.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158343_k127_808948_10	264731.PRU_1343	1.077e-23	108.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,2FNW6@200643|Bacteroidia	976|Bacteroidetes	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158343_k127_808948_16	857293.CAAU_2054	4.892e-16	80.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,36NYT@31979|Clostridiaceae	186801|Clostridia	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR25158343_k127_808948_11	292459.STH876	4.563e-23	102.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158343_k127_808948_1	1156937.MFUM_80005	4.142e-141	461.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,37GG5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158343_k127_808948_14	316274.Haur_2708	1.68e-18	94.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,375M0@32061|Chloroflexia	32061|Chloroflexia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158343_k127_808948_21	1265502.KB905953_gene760	2.405e-05	54.0	COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria,2WGTG@28216|Betaproteobacteria,4AIN6@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158343_k127_808948_17	7739.XP_002594906.1	7.85e-14	78.0	COG0500@1|root,KOG4058@2759|Eukaryota,39SC5@33154|Opisthokonta,3BDSU@33208|Metazoa,3CX4A@33213|Bilateria,488H1@7711|Chordata	33208|Metazoa	Q	positive regulation of sensory perception of pain	FAM173B	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016020,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0019866,GO:0030061,GO:0031090,GO:0031644,GO:0031646,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044057,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0048518,GO:0050789,GO:0051239,GO:0051240,GO:0051930,GO:0051931,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1904058	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_808948_25	1408417.JHYB01000002_gene377	0.0003638	46.0	COG1722@1|root,COG1722@2|Bacteria,3WUX2@544448|Tenericutes	544448|Tenericutes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158343_k127_808948_6	314230.DSM3645_22876	2.228e-59	220.0	COG1570@1|root,COG1570@2|Bacteria,2IXGG@203682|Planctomycetes	203682|Planctomycetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158343_k127_808948_19	1101188.KI912155_gene1498	5.078e-12	72.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
SRR25158343_k127_841792_0	1545701.LACWKB10_0073	3.577e-99	337.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158343_k127_841792_2	2074.JNYD01000005_gene3306	4.244e-05	52.0	COG1051@1|root,COG1051@2|Bacteria,2IQZT@201174|Actinobacteria,4E5NW@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_841792_1	743718.Isova_2519	7.359e-35	149.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4F495@85017|Promicromonosporaceae	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
SRR25158343_k127_875803_4	1116231.SMA_1505	2.948e-77	264.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158343_k127_875803_2	255470.cbdbA543	1.806e-101	342.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,34CN2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158343_k127_875803_16	1469245.JFBG01000084_gene192	3.094e-07	63.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1WVY3@135613|Chromatiales	135613|Chromatiales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_875803_0	1408439.JHXW01000002_gene650	1.249e-231	744.0	COG0653@1|root,COG0653@2|Bacteria,378NS@32066|Fusobacteria	32066|Fusobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158343_k127_875803_13	862514.HMPREF0623_1694	7.042e-12	70.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158343_k127_875803_3	443906.CMM_0515	1.213e-82	290.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4FKF7@85023|Microbacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158343_k127_875803_5	237368.SCABRO_00086	1.931e-73	256.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_24,PDDEXK_1
SRR25158343_k127_875803_8	864702.OsccyDRAFT_1690	1.216e-37	149.0	COG0546@1|root,COG0546@2|Bacteria,1G52P@1117|Cyanobacteria,1HB0I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Haloacid dehalogenase-like hydrolase	cbbZp	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158343_k127_875803_7	1192034.CAP_2274	1.195e-53	192.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2WNTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158343_k127_875803_15	63737.Npun_R0530	8.497e-10	64.0	2CCDG@1|root,32RVE@2|Bacteria,1G7TR@1117|Cyanobacteria,1HPGG@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_875803_12	1434325.AZQN01000004_gene1819	1.934e-13	77.0	2CAGA@1|root,331BW@2|Bacteria,4NXN3@976|Bacteroidetes,47SRW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_875803_10	479434.Sthe_1164	4.563e-23	102.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,27YGT@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158343_k127_875803_1	1229780.BN381_250056	1.876e-162	526.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRR25158343_k127_875803_9	1278304.JAFR01000006_gene443	3.538e-31	128.0	COG0782@1|root,COG0782@2|Bacteria,3WTDQ@544448|Tenericutes	544448|Tenericutes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158343_k127_875803_6	1541959.KQ51_00006	1.856e-71	257.0	COG0442@1|root,COG0442@2|Bacteria	2|Bacteria	J	prolyl-tRNA aminoacylation	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.proS,iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158343_k127_875803_11	565034.BHWA1_00686	1.022e-14	83.0	COG0263@1|root,COG0263@2|Bacteria,2J6GB@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158343_k127_875803_14	765420.OSCT_0359	1.104e-11	68.0	COG1266@1|root,COG1266@2|Bacteria,2GBQ5@200795|Chloroflexi,37605@32061|Chloroflexia	32061|Chloroflexia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158343_k127_878186_0	1451261.AS96_14610	6.203e-14	85.0	COG3704@1|root,COG3704@2|Bacteria	2|Bacteria	U	protein secretion by the type IV secretion system	-	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158343_k127_881939_3	742733.HMPREF9469_03625	1.853e-15	86.0	2E1MQ@1|root,32WYT@2|Bacteria,1VB8R@1239|Firmicutes,24R84@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_881939_4	1121934.AUDX01000017_gene664	1.157e-11	72.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158343_k127_881939_5	1158610.UC3_00232	3.081e-06	56.0	COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HIA0@91061|Bacilli,4B01E@81852|Enterococcaceae	91061|Bacilli	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158343_k127_881939_1	452863.Achl_2796	4.014e-62	229.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158343_k127_881939_2	935839.JAGJ01000030_gene3025	9.591e-19	94.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4F3D2@85017|Promicromonosporaceae	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_881939_0	497964.CfE428DRAFT_0788	6.167e-107	349.0	COG0362@1|root,COG0362@2|Bacteria,46SDE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158343_k127_884013_6	218140.BPSY_0981	5.773e-08	61.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4D13A@85004|Bifidobacteriales	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158343_k127_884013_2	1121372.AULK01000005_gene1583	2.192e-46	170.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4FNQ7@85023|Microbacteriaceae	201174|Actinobacteria	O	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158343_k127_884013_4	1123315.AUIP01000001_gene1531	7.581e-27	116.0	COG1733@1|root,COG1733@2|Bacteria,1VH3Q@1239|Firmicutes,4HNMI@91061|Bacilli	91061|Bacilli	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158343_k127_884013_3	264462.Bd1346	1.691e-36	144.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,42W1X@68525|delta/epsilon subdivisions,2MTXK@213481|Bdellovibrionales,2WRUK@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158343_k127_884013_5	1380386.JIAW01000001_gene4730	1.132e-25	110.0	COG2315@1|root,COG2315@2|Bacteria,2IHRR@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158343_k127_884013_0	1150399.AQYK01000001_gene1865	2.018e-155	505.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FK9S@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_884013_1	1121288.AULL01000013_gene1626	1.605e-61	220.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia,3ZPN5@59732|Chryseobacterium	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158343_k127_906092_0	1472418.BBJC01000007_gene2643	7.341e-16	85.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Competence protein	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158343_k127_906092_1	1121335.Clst_0952	1.844e-15	83.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24U24@186801|Clostridia,3WJ3V@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158343_k127_922382_0	562743.JH976435_gene3324	1.817e-15	88.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU03790	AA_kinase,ACT,ACT_7
SRR25158343_k127_922382_1	1385515.N791_10860	6.956e-12	76.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,1X5T7@135614|Xanthomonadales	135614|Xanthomonadales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve_3
SRR25158343_k127_922382_3	1338011.BD94_1214	0.0001024	46.0	COG2755@1|root,COG2755@2|Bacteria,4NPMA@976|Bacteroidetes,1I2G1@117743|Flavobacteriia,34QEZ@308865|Elizabethkingia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_922382_2	1218108.KB908300_gene2567	2.704e-07	56.0	COG2755@1|root,COG2755@2|Bacteria,4NPMA@976|Bacteroidetes,1I2G1@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_953097_1	349161.Dred_0641	1.212e-43	166.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,260IB@186807|Peptococcaceae	186801|Clostridia	O	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_953097_2	525904.Tter_1432	4.713e-41	162.0	COG2890@1|root,COG2890@2|Bacteria,2NPDN@2323|unclassified Bacteria	2|Bacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.297,2.1.1.298	ko:K02493,ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009,ko03012	-	-	-	MTS
SRR25158343_k127_953097_3	1077144.AGFF01000004_gene2100	6.351e-25	112.0	COG0317@1|root,COG0317@2|Bacteria,2IC8P@201174|Actinobacteria	201174|Actinobacteria	KT	Guanosine polyphosphate pyrophosphohydrolases synthetases	spoT	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158343_k127_953097_0	525904.Tter_1654	6.91e-63	219.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158343_k127_958319_4	700015.Corgl_1596	6.682e-28	116.0	2DT5B@1|root,33ISI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_958319_1	653733.Selin_1951	6.055e-180	570.0	COG0050@1|root,COG0050@2|Bacteria	2|Bacteria	J	translation elongation factor activity	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_958319_0	1158318.ATXC01000001_gene1277	1.706e-269	845.0	COG0480@1|root,COG0480@2|Bacteria,2G3NW@200783|Aquificae	200783|Aquificae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_958319_3	352165.HMPREF7215_0920	3.049e-45	172.0	COG0049@1|root,COG0049@2|Bacteria,3TAVX@508458|Synergistetes	508458|Synergistetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158343_k127_958319_2	1121344.JHZO01000004_gene1221	4.437e-54	194.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158343_k127_968404_7	868131.MSWAN_1387	1.051e-06	60.0	arCOG02566@1|root,arCOG02566@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_968404_8	436229.JOEH01000001_gene1470	1.587e-05	56.0	COG1470@1|root,COG1470@2|Bacteria,2I2TR@201174|Actinobacteria,2NH7Y@228398|Streptacidiphilus	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF916
SRR25158343_k127_968404_5	1499967.BAYZ01000080_gene910	2.26e-08	69.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,ESPR,LVIVD,YadA_anchor,YadA_head,YadA_stalk
SRR25158343_k127_968404_2	379731.PST_0153	7.233e-19	96.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1S1S2@1236|Gammaproteobacteria,1Z0ZV@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA,Pkinase,dCache_1
SRR25158343_k127_968404_1	1382306.JNIM01000001_gene751	2.82e-48	181.0	COG0745@1|root,COG0745@2|Bacteria,2G6H6@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_968404_0	981383.AEWH01000046_gene1359	2.656e-72	249.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli	91061|Bacilli	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158343_k127_968404_3	639282.DEFDS_1815	6.097e-14	84.0	COG0280@1|root,COG0280@2|Bacteria,2GEYU@200930|Deferribacteres	200930|Deferribacteres	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
SRR25158343_k127_968404_4	89187.ISM_10695	5.881e-13	81.0	COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,2TVFP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
## 512 queries scanned
## Total time (seconds): 3.9208524227142334
## Rate: 130.58 q/s