## Wed Feb 18 23:41:32 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158343_bin.2.fa -m mmseqs --output SRR25158343_bin.2 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158343_bin.2 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158343_k127_1102016_21	216594.MMAR_3587	3.108e-26	118.0	2CK2M@1|root,32SBE@2|Bacteria,2IHIU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1102016_30	56780.SYN_00509	3.063e-15	89.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	ccrB	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1102016_20	373903.Hore_00200	1.634e-28	123.0	2F7D8@1|root,33ZU9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1102016_33	1345695.CLSA_c36540	1.405e-14	77.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,36W69@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158343_k127_1102016_27	1232449.BAHV02000002_gene248	2.217e-18	93.0	COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,25BC7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158343_k127_1102016_11	33876.JNXY01000038_gene8104	8.517e-43	166.0	COG0483@1|root,COG0483@2|Bacteria,2H8ZM@201174|Actinobacteria	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
SRR25158343_k127_1102016_13	1173027.Mic7113_5957	3.598e-37	155.0	COG4301@1|root,COG4301@2|Bacteria,1G2R0@1117|Cyanobacteria,1HETR@1150|Oscillatoriales	1117|Cyanobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158343_k127_1102016_8	457415.HMPREF1006_00222	4.999e-60	215.0	COG0217@1|root,COG0217@2|Bacteria,3T9QN@508458|Synergistetes	508458|Synergistetes	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158343_k127_1102016_10	1111479.AXAR01000007_gene920	3.153e-51	186.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,4HGM3@91061|Bacilli,279QS@186823|Alicyclobacillaceae	91061|Bacilli	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158343_k127_1102016_43	1537715.JQFJ01000002_gene790	2.439e-05	54.0	COG0295@1|root,COG0295@2|Bacteria,1RKQ5@1224|Proteobacteria,2U96B@28211|Alphaproteobacteria,2KD8D@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158343_k127_1102016_18	324602.Caur_1418	3.847e-29	123.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi,3774D@32061|Chloroflexia	32061|Chloroflexia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158343_k127_1102016_4	1117108.PAALTS15_06344	1.514e-133	434.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,26RSM@186822|Paenibacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158343_k127_1102016_45	566466.NOR53_1376	0.0001577	50.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1JA64@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pfam:N_methyl_3	pilA	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
SRR25158343_k127_1102016_7	1122947.FR7_3378	1.148e-72	261.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158343_k127_1102016_1	314231.FP2506_03675	4.396e-149	479.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2PJE8@255475|Aurantimonadaceae	28211|Alphaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158343_k127_1102016_25	1408254.T458_16010	6.439e-22	104.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HM0B@91061|Bacilli,26U1A@186822|Paenibacillaceae	91061|Bacilli	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158343_k127_1102016_23	1120973.AQXL01000105_gene2554	5.977e-22	103.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,278JG@186823|Alicyclobacillaceae	91061|Bacilli	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158343_k127_1102016_38	329726.AM1_4424	6.28e-10	66.0	COG1214@1|root,COG1214@2|Bacteria,1G57V@1117|Cyanobacteria	1117|Cyanobacteria	O	COG1214 Inactive homolog of metal-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
SRR25158343_k127_1102016_3	246194.CHY_1168	1.525e-139	460.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,42F5Q@68295|Thermoanaerobacterales	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158343_k127_1102016_34	414996.IL38_07855	2.814e-14	80.0	COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,40929@622450|Actinopolysporales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025,ko:K18569	ko00332,ko01130,map00332,map01130	-	R10748	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158343_k127_1102016_9	1121936.AUHI01000004_gene1639	7.941e-53	196.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli	91061|Bacilli	S	metallophosphoesterase	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
SRR25158343_k127_1102016_2	68170.KL590489_gene10375	3.552e-141	465.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4E5GJ@85010|Pseudonocardiales	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1102016_28	1449058.JQKT01000007_gene1342	2.686e-17	96.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4FMW7@85023|Microbacteriaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1102016_12	648757.Rvan_2759	1.896e-37	155.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,2UCGF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_1102016_26	1437425.CSEC_2042	3.138e-20	96.0	COG4403@1|root,COG4403@2|Bacteria,2JHAZ@204428|Chlamydiae	204428|Chlamydiae	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1102016_42	1089546.AQUI01000002_gene883	5.096e-06	55.0	28U3I@1|root,2ZG9M@2|Bacteria,2HCH1@201174|Actinobacteria	201174|Actinobacteria	S	zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC3
SRR25158343_k127_1102016_14	253839.SSNG_04896	4.22e-37	145.0	28MCB@1|root,2ZAQI@2|Bacteria,2IAWT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1102016_35	298653.Franean1_2653	8.865e-13	76.0	COG5635@1|root,COG5635@2|Bacteria,2H2QE@201174|Actinobacteria	201174|Actinobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1102016_36	106370.Francci3_0809	1.14e-12	74.0	COG4734@1|root,COG4734@2|Bacteria,2IQRG@201174|Actinobacteria,4EW4U@85013|Frankiales	201174|Actinobacteria	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
SRR25158343_k127_1102016_31	743525.TSC_c01320	3.64e-15	82.0	COG1051@1|root,COG1051@2|Bacteria,1WJX0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1102016_24	1444712.BN1013_01163	6.006e-22	104.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158343_k127_1102016_6	103733.JNYO01000025_gene8934	1.551e-97	341.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria,4DXPZ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter transmembrane region	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1102016_40	1463934.JOCF01000060_gene3428	8.412e-09	65.0	COG4106@1|root,COG4106@2|Bacteria,2IAN9@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158343_k127_1102016_39	1408473.JHXO01000004_gene11	2.622e-09	68.0	COG0637@1|root,COG0637@2|Bacteria,4NHHK@976|Bacteroidetes,2FV0I@200643|Bacteroidia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158343_k127_1102016_5	1380347.JNII01000005_gene3546	1.255e-110	375.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1102016_32	1223523.H340_15886	9.219e-15	80.0	COG1846@1|root,COG1846@2|Bacteria,2IFRN@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158343_k127_1102016_29	113355.CM001775_gene2244	2.022e-16	88.0	COG0170@1|root,COG0170@2|Bacteria,1G25U@1117|Cyanobacteria	1117|Cyanobacteria	I	Dolichol kinase	-	GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0006766,GO:0006775,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0010276,GO:0016101,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017144,GO:0018130,GO:0033306,GO:0034308,GO:0042360,GO:0042362,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1903173	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
SRR25158343_k127_1102016_0	446469.Sked_08040	9.215e-158	518.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K12954,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRR25158343_k127_1102016_22	1463857.JOFZ01000001_gene5825	5.754e-24	117.0	COG2273@1|root,COG2273@2|Bacteria,2GJQP@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16,Ricin_B_lectin
SRR25158343_k127_1102016_19	1463825.JNXC01000053_gene24	8.382e-29	118.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4E1CS@85010|Pseudonocardiales	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,Ricin_B_lectin,ThuA
SRR25158343_k127_1102016_41	1144275.COCOR_00648	1.714e-06	59.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158343_k127_1102016_17	1075090.GOAMR_03_01200	7.775e-30	133.0	COG0477@1|root,COG2814@2|Bacteria,2GJKY@201174|Actinobacteria,4GAQB@85026|Gordoniaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1102016_15	930171.Asphe3_02190	4.659e-37	161.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158343_k127_1102016_37	1033730.CAHG01000007_gene2614	5.794e-11	76.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM9_1,Glyco_hydro_8,Polysacc_deac_1
SRR25158343_k127_1102016_46	1449336.JQLO01000001_gene167	0.0002773	52.0	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	yhcS	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158343_k127_1102016_16	1050202.KB913024_gene1834	4.852e-32	140.0	COG1215@1|root,COG1215@2|Bacteria,2I97V@201174|Actinobacteria,408RV@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158343_k127_1107900_0	436114.SYO3AOP1_1393	2.923e-10	71.0	COG2801@1|root,COG2801@2|Bacteria,2G3YF@200783|Aquificae	200783|Aquificae	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,HTH_Tnp_Tc3_2,rve,rve_3
SRR25158343_k127_111342_7	1051632.TPY_2529	1.749e-24	117.0	COG0438@1|root,COG0438@2|Bacteria,1UMR3@1239|Firmicutes	1239|Firmicutes	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1,TPR_8
SRR25158343_k127_111342_2	324602.Caur_1741	9.425e-40	162.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_1,Glycos_transf_2
SRR25158343_k127_111342_0	997296.PB1_00360	6.392e-80	278.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	glgP	-	2.4.1.1,2.4.1.11	ko:K16153	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Glyco_trans_1_2,Glyco_transf_4,Glyco_transf_8,Glycogen_syn,Glycos_transf_1,Glycos_transf_2,Phosphorylase
SRR25158343_k127_111342_13	1236497.BAJQ01000028_gene2451	0.0001872	48.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,2FT5R@200643|Bacteroidia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158343_k127_111342_9	374847.Kcr_0841	5.369e-19	94.0	arCOG03850@1|root,arCOG03850@2157|Archaea	2157|Archaea	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158343_k127_111342_14	1121441.AUCX01000033_gene309	0.0003393	52.0	COG0438@1|root,COG0438@2|Bacteria,1R9QG@1224|Proteobacteria,42PQQ@68525|delta/epsilon subdivisions,2WTQJ@28221|Deltaproteobacteria,2M9KJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158343_k127_111342_1	58123.JOFJ01000005_gene1421	7.727e-48	186.0	COG3757@1|root,COG3757@2|Bacteria,2HUW8@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DUF1906
SRR25158343_k127_111342_3	3067.XP_002957368.1	8.304e-33	141.0	COG3325@1|root,KOG2806@2759|Eukaryota	2759|Eukaryota	G	chitin binding	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,Lectin_C,LysM,SRCR
SRR25158343_k127_111342_12	86416.Clopa_3372	7.388e-05	50.0	2EDVT@1|root,337QY@2|Bacteria,1VJDP@1239|Firmicutes,24U27@186801|Clostridia,36T4D@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
SRR25158343_k127_111342_10	246194.CHY_1666	6.547e-14	76.0	2DYXT@1|root,32V67@2|Bacteria,1VCUF@1239|Firmicutes,24QC0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_111342_6	1499685.CCFJ01000055_gene1927	3.375e-29	123.0	COG5492@1|root,COG5492@2|Bacteria,1W495@1239|Firmicutes,4I0QJ@91061|Bacilli,1ZKIA@1386|Bacillus	91061|Bacilli	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_111342_4	1283283.ATXA01000001_gene629	1.674e-31	143.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria	2|Bacteria	N	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
SRR25158343_k127_111342_11	284031.JNXD01000011_gene784	3.544e-08	67.0	2AVW6@1|root,31MQ0@2|Bacteria,2II8X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1119293_3	1137281.D778_01491	0.000803	54.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,1I1PS@117743|Flavobacteriia	976|Bacteroidetes	MUW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SRR25158343_k127_1119293_0	1906.SFRA_12915	1.366e-58	219.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_1119293_1	349520.PPE_04508	7.2e-32	142.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,26RVC@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158343_k127_1119293_2	748224.HMPREF9436_01491	1.34e-06	55.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia,3WKCK@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158343_k127_1141695_5	710687.KI912270_gene5026	1.355e-05	48.0	2B9ZR@1|root,323DD@2|Bacteria,2H80V@201174|Actinobacteria,23E7J@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1141695_0	635013.TherJR_1377	1.283e-158	520.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158343_k127_1141695_1	484770.UFO1_2023	5.702e-63	230.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,4H2B6@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158343_k127_1141695_3	697281.Mahau_1834	3.032e-27	122.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FK4@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158343_k127_1141695_2	698769.JFBD01000024_gene1884	2.541e-34	132.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1187568_0	358681.BBR47_37310	2.01e-41	166.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26R54@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158343_k127_1250299_32	590998.Celf_0320	1.608e-34	138.0	COG0494@1|root,COG0494@2|Bacteria,2GKUV@201174|Actinobacteria,4F2CI@85016|Cellulomonadaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1250299_34	1121890.AUDO01000010_gene359	1.269e-31	137.0	COG0189@1|root,COG0189@2|Bacteria,4PK43@976|Bacteroidetes,1IDSB@117743|Flavobacteriia,2NZ30@237|Flavobacterium	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_62	745718.JADT01000002_gene2430	8.963e-05	47.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_45	339670.Bamb_0825	2.859e-17	93.0	COG0837@1|root,COG1737@1|root,COG0837@2|Bacteria,COG1737@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1K3IA@119060|Burkholderiaceae	28216|Betaproteobacteria	F	belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
SRR25158343_k127_1250299_7	575590.HMPREF0156_01408	3.624e-99	329.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158343_k127_1250299_35	1122173.AXVL01000001_gene1691	1.492e-31	140.0	COG1122@1|root,COG3468@1|root,COG1122@2|Bacteria,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	sca2	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	Autotransporter,Spherulin4
SRR25158343_k127_1250299_8	316274.Haur_2832	2.477e-95	327.0	COG1626@1|root,COG1626@2|Bacteria	2|Bacteria	G	alpha,alpha-trehalase activity	treA	GO:0003674,GO:0003824,GO:0004553,GO:0004555,GO:0005575,GO:0005623,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006970,GO:0006972,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009628,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071704,GO:0104004,GO:1901575	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	iAF1260.b1197,iB21_1397.B21_01182,iBWG_1329.BWG_1022,iECBD_1354.ECBD_2425,iECB_1328.ECB_01172,iECDH10B_1368.ECDH10B_1250,iECDH1ME8569_1439.ECDH1ME8569_1136,iECD_1391.ECD_01172,iECUMN_1333.ECUMN_1493,iETEC_1333.ETEC_1301,iEcDH1_1363.EcDH1_2451,iEcHS_1320.EcHS_A1301,iEcolC_1368.EcolC_2429,iJO1366.b1197,iJR904.b1197,iSBO_1134.SBO_3518,iY75_1357.Y75_RS06245	Trehalase
SRR25158343_k127_1250299_3	1122138.AQUZ01000036_gene5443	1.495e-120	390.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria,4DMXX@85009|Propionibacteriales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158343_k127_1250299_22	1137799.GZ78_03755	9.014e-50	203.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XIWS@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158343_k127_1250299_9	867902.Ornrh_1375	1.549e-91	315.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158343_k127_1250299_33	391623.TERMP_00144	6.62e-32	134.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,2437T@183968|Thermococci	183968|Thermococci	I	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158343_k127_1250299_19	1121957.ATVL01000001_gene3558	2.562e-56	204.0	COG2220@1|root,COG2220@2|Bacteria,4P38Z@976|Bacteroidetes	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158343_k127_1250299_42	944560.HMPREF9058_0234	2.92e-22	107.0	COG2755@1|root,COG2755@2|Bacteria,2GRDF@201174|Actinobacteria,4D4AK@85005|Actinomycetales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_1250299_12	1463887.KL590024_gene1492	2.913e-74	256.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158343_k127_1250299_14	1449346.JQMO01000003_gene5277	3.226e-69	242.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,2M22M@2063|Kitasatospora	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1250299_37	471852.Tcur_2406	2.729e-29	131.0	COG0568@1|root,COG0568@2|Bacteria,2ID1P@201174|Actinobacteria,4EGBU@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_1250299_61	522306.CAP2UW1_0976	4.451e-05	51.0	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_57	502558.EGYY_27610	1.737e-06	56.0	COG1846@1|root,COG1846@2|Bacteria,2HWGC@201174|Actinobacteria,4CYCW@84998|Coriobacteriia	84998|Coriobacteriia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158343_k127_1250299_17	926569.ANT_03800	7.068e-62	222.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158343_k127_1250299_28	330084.JNYZ01000003_gene2182	4.181e-38	158.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DXKM@85010|Pseudonocardiales	201174|Actinobacteria	G	G5	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158343_k127_1250299_0	86416.Clopa_1446	1.445e-227	743.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,36DGD@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158343_k127_1250299_29	63737.Npun_R5371	2.261e-37	156.0	COG4301@1|root,COG4301@2|Bacteria,1G2R0@1117|Cyanobacteria,1HMIR@1161|Nostocales	1117|Cyanobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158343_k127_1250299_20	938289.CAJN020000002_gene728	7.837e-54	199.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,268FX@186813|unclassified Clostridiales	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
SRR25158343_k127_1250299_64	1306990.BARG01000063_gene7231	0.0004939	52.0	COG2866@1|root,COG2866@2|Bacteria,2GP4P@201174|Actinobacteria	201174|Actinobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158343_k127_1250299_5	871968.DESME_15175	4.828e-113	379.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158343_k127_1250299_6	760142.Hipma_0462	4.922e-102	349.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2M6H7@213113|Desulfurellales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158343_k127_1250299_39	342949.PNA2_1091	1.07e-25	113.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,245EJ@183968|Thermococci	183968|Thermococci	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
SRR25158343_k127_1250299_40	285535.JOEY01000022_gene573	1.335e-25	111.0	COG1051@1|root,COG1051@2|Bacteria,2GT4E@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158343_k127_1250299_13	1382304.JNIL01000001_gene3207	7.273e-74	253.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158343_k127_1250299_66	1907.SGLAU_25375	0.0007097	53.0	2DC7T@1|root,2ZD72@2|Bacteria,2IKX2@201174|Actinobacteria	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PqqD,Transglut_core3
SRR25158343_k127_1250299_15	1907.SGLAU_25370	8.093e-66	254.0	COG0367@1|root,COG0367@2|Bacteria,2GMIY@201174|Actinobacteria	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
SRR25158343_k127_1250299_52	243232.MJ_0226	6.571e-12	74.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,23QP7@183939|Methanococci	183939|Methanococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158343_k127_1250299_53	78245.Xaut_1568	1.044e-10	72.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,2UHQ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
SRR25158343_k127_1250299_16	2074.JNYD01000032_gene6473	3.86e-62	231.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DYGX@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_1250299_1	596152.DesU5LDRAFT_4062	1.848e-157	510.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2M812@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	AlkA N-terminal domain	ada	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158343_k127_1250299_26	1003195.SCAT_2708	2.192e-41	157.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158343_k127_1250299_18	298653.Franean1_5282	2.556e-57	210.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	pyrD	-	1.3.1.14,1.3.98.1	ko:K00226,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,DHO_dh,NAD_binding_1
SRR25158343_k127_1250299_41	768706.Desor_5016	1.835e-22	108.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
SRR25158343_k127_1250299_47	290340.AAur_2161	1.179e-15	92.0	2EE91@1|root,3383F@2|Bacteria,2IAWN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_43	1463887.KL589986_gene3033	1.393e-20	108.0	COG1749@1|root,COG1749@2|Bacteria,2I2X3@201174|Actinobacteria	201174|Actinobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,Mo-co_dimer,fn3
SRR25158343_k127_1250299_59	1996.JOFO01000070_gene2262	1.427e-05	56.0	COG3469@1|root,COG3469@2|Bacteria,2GJH0@201174|Actinobacteria,4EG1P@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 18	chiA	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_18,fn3
SRR25158343_k127_1250299_56	1304880.JAGB01000001_gene573	3.629e-07	57.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158343_k127_1250299_49	479435.Kfla_0649	3.448e-13	74.0	2EQEE@1|root,33I0E@2|Bacteria,2GS5M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_58	309800.C498_10831	4.99e-06	57.0	COG1917@1|root,COG3435@1|root,arCOG02994@2157|Archaea,arCOG03000@2157|Archaea,2XV3N@28890|Euryarchaeota,23SUX@183963|Halobacteria	183963|Halobacteria	Q	COG3435 Gentisate 1,2-dioxygenase	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
SRR25158343_k127_1250299_63	101852.XP_008081710.1	0.0001814	51.0	COG3193@1|root,2SMVS@2759|Eukaryota,3A486@33154|Opisthokonta,3P441@4751|Fungi,3QWK7@4890|Ascomycota	4751|Fungi	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158343_k127_1250299_24	1545701.LACWKB10_1464	1.268e-46	176.0	COG4047@1|root,COG4047@2|Bacteria,1U5P1@1239|Firmicutes,4IFDM@91061|Bacilli,3F697@33958|Lactobacillaceae	91061|Bacilli	L	oxidized base lesion DNA N-glycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_25	485913.Krac_5282	1.016e-43	165.0	COG0127@1|root,COG0127@2|Bacteria	2|Bacteria	F	nucleoside triphosphate catabolic process	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Ham1p_like
SRR25158343_k127_1250299_30	56107.Cylst_1978	6.946e-37	141.0	COG2337@1|root,COG2337@2|Bacteria,1G7P3@1117|Cyanobacteria,1HPNZ@1161|Nostocales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158343_k127_1250299_48	56107.Cylst_1979	8.086e-14	74.0	COG0864@1|root,COG0864@2|Bacteria,1G9E4@1117|Cyanobacteria,1HPW8@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_4	1157943.KB892705_gene706	1.546e-113	394.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,235P5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158343_k127_1250299_36	1120792.JAFV01000001_gene2044	1.75e-29	127.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,36XD7@31993|Methylocystaceae	28211|Alphaproteobacteria	E	TOBE domain	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158343_k127_1250299_46	932677.PAJ_p0012	8.973e-16	82.0	COG0745@1|root,COG0745@2|Bacteria,1MVQT@1224|Proteobacteria,1RNSY@1236|Gammaproteobacteria,3W0A2@53335|Pantoea	1236|Gammaproteobacteria	T	COG Signal transduction mechanisms	-	-	-	ko:K18144	ko01501,map01501	M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1250299_50	1131813.AQVT01000001_gene274	3.813e-13	75.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,1JS5P@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1250299_10	1297617.JPJD01000009_gene2950	1.653e-77	275.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,2689Q@186813|unclassified Clostridiales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_1250299_23	1423767.BALU01000005_gene913	1.437e-47	181.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158343_k127_1250299_21	760142.Hipma_0827	7.38e-53	207.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1250299_38	289376.THEYE_A1186	7.305e-27	115.0	COG2003@1|root,COG2003@2|Bacteria,3J12V@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158343_k127_1250299_51	1123013.AUIC01000002_gene976	1.063e-12	71.0	COG3041@1|root,COG3041@2|Bacteria	2|Bacteria	S	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
SRR25158343_k127_1250299_55	742733.HMPREF9469_01346	1.261e-08	66.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia,220KS@1506553|Lachnoclostridium	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158343_k127_1250299_11	566461.SSFG_01032	2.95e-76	282.0	COG0791@1|root,COG3291@1|root,COG0791@2|Bacteria,COG3291@2|Bacteria,2GT7N@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall-associated hydrolases (Invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158343_k127_1250299_54	1297617.JPJD01000085_gene614	4.321e-10	62.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,2691F@186813|unclassified Clostridiales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158343_k127_1250299_2	1230343.CANP01000008_gene919	2.282e-131	434.0	COG2242@1|root,COG2242@2|Bacteria,1PEB4@1224|Proteobacteria,1T5ZE@1236|Gammaproteobacteria,1JFKT@118969|Legionellales	118969|Legionellales	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1250299_27	1089551.KE386572_gene1955	5.921e-41	172.0	COG3119@1|root,COG3119@2|Bacteria,1MYHH@1224|Proteobacteria,2UA67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158343_k127_1250299_31	504832.OCAR_7731	4.679e-36	146.0	2E54J@1|root,32ZXH@2|Bacteria,1R9DG@1224|Proteobacteria,2U2YG@28211|Alphaproteobacteria,3JR4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1302352_24	670307.HYPDE_37458	2.556e-57	210.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158343_k127_1302352_0	1444711.CCJF01000005_gene196	5.726e-253	805.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2JFD0@204428|Chlamydiae	204428|Chlamydiae	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158343_k127_1302352_13	1444711.CCJF01000005_gene195	8.74e-77	265.0	COG1273@1|root,COG1273@2|Bacteria,2JGQ1@204428|Chlamydiae	204428|Chlamydiae	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158343_k127_1302352_38	979556.MTES_2957	8.432e-24	108.0	COG3976@1|root,COG3976@2|Bacteria,2IQ4E@201174|Actinobacteria,4FQGD@85023|Microbacteriaceae	201174|Actinobacteria	S	FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
SRR25158343_k127_1302352_17	452863.Achl_2360	2.156e-65	234.0	COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,1W90X@1268|Micrococcaceae	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158343_k127_1302352_5	485913.Krac_3439	4.008e-127	423.0	COG1018@1|root,COG1018@2|Bacteria,2G9BE@200795|Chloroflexi	2|Bacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1,NQR2_RnfD_RnfE
SRR25158343_k127_1302352_34	69014.TK1719	9.494e-28	128.0	COG2244@1|root,arCOG02209@2157|Archaea,2XZJ5@28890|Euryarchaeota,243YW@183968|Thermococci	183968|Thermococci	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
SRR25158343_k127_1302352_16	373994.Riv7116_1073	2.561e-66	239.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,1HMER@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRR25158343_k127_1302352_18	565033.GACE_0494	2.35e-65	237.0	COG0438@1|root,arCOG01403@2157|Archaea,2XUUY@28890|Euryarchaeota,24798@183980|Archaeoglobi	183980|Archaeoglobi	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1302352_12	118173.KB235914_gene4084	2.3e-79	274.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1302352_48	1167006.UWK_02002	2.719e-10	72.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42MDA@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	General glycosylation pathway protein	pglH	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.292	ko:K17249	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1302352_23	345219.Bcoa_0878	6.176e-58	217.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,4IM2M@91061|Bacilli,1ZIX0@1386|Bacillus	91061|Bacilli	S	Polysaccharide pyruvyl transferase	-	-	-	ko:K16710	-	-	-	-	ko00000	-	-	-	PS_pyruv_trans
SRR25158343_k127_1302352_52	1211035.CD30_13785	4.305e-06	61.0	COG4485@1|root,COG4485@2|Bacteria,1VI49@1239|Firmicutes	1239|Firmicutes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158343_k127_1302352_26	1210908.HSB1_35020	1.999e-46	188.0	arCOG07351@1|root,arCOG07351@2157|Archaea,2XXPD@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1302352_1	667014.Thein_0592	1.843e-225	719.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,2GH2W@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Trehalose-phosphatase	-	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158343_k127_1302352_22	1121889.AUDM01000008_gene818	1.769e-58	211.0	COG2227@1|root,COG2227@2|Bacteria,4NWP3@976|Bacteroidetes,1I7B4@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1302352_41	1461580.CCAS010000016_gene1984	6.517e-16	86.0	COG0664@1|root,COG0664@2|Bacteria,1VD7I@1239|Firmicutes,4HMTP@91061|Bacilli	91061|Bacilli	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_1302352_40	1396418.BATQ01000170_gene2658	9.939e-17	84.0	COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia,2IVU2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Response_reg
SRR25158343_k127_1302352_44	395493.BegalDRAFT_0437	4.723e-13	74.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,GAF,GAF_2,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,Response_reg
SRR25158343_k127_1302352_30	357808.RoseRS_3771	1.313e-38	164.0	COG2202@1|root,COG2203@1|root,COG3290@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,2GBK6@200795|Chloroflexi,3770Y@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158343_k127_1302352_35	398527.Bphyt_6719	2.462e-27	128.0	COG3614@1|root,COG5001@1|root,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_3,PAS_4,PAS_9
SRR25158343_k127_1302352_55	1380391.JIAS01000015_gene129	0.0002368	47.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,2UBU4@28211|Alphaproteobacteria,2JTUG@204441|Rhodospirillales	204441|Rhodospirillales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158343_k127_1302352_9	1463934.JOCF01000055_gene2016	3.414e-94	340.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158343_k127_1302352_43	1437425.CSEC_0352	6.343e-15	76.0	2EIK5@1|root,33CBF@2|Bacteria,2JH9H@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1302352_54	1122599.AUGR01000014_gene617	0.000127	51.0	COG4968@1|root,COG4968@2|Bacteria,1MZT0@1224|Proteobacteria,1SEXY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158343_k127_1302352_6	743718.Isova_2404	1.372e-118	388.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4F3XF@85017|Promicromonosporaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
SRR25158343_k127_1302352_58	368407.Memar_0449	0.0005318	53.0	COG1061@1|root,arCOG00881@2157|Archaea,2Y6AU@28890|Euryarchaeota,2NAK7@224756|Methanomicrobia	224756|Methanomicrobia	K	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
SRR25158343_k127_1302352_36	1278308.KB907083_gene362	1.975e-24	118.0	COG1807@1|root,COG1807@2|Bacteria,2H5NR@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1302352_21	525909.Afer_1990	3.087e-60	223.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CNDB@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158343_k127_1302352_20	1463934.JOCF01000073_gene5807	2.757e-61	218.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158343_k127_1302352_7	395965.Msil_2410	2.791e-118	395.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TRNM@28211|Alphaproteobacteria,3NAQK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRR25158343_k127_1302352_25	1304880.JAGB01000002_gene1638	4.917e-56	212.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1302352_14	632335.Calkr_2381	2.769e-70	252.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,42G06@68295|Thermoanaerobacterales	186801|Clostridia	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1302352_2	1121957.ATVL01000006_gene2888	1.707e-159	514.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158343_k127_1302352_27	648757.Rvan_0674	3.314e-45	171.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,3N6P3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158343_k127_1302352_11	390989.JOEG01000006_gene839	5.427e-91	308.0	COG1752@1|root,COG1752@2|Bacteria,2IA6V@201174|Actinobacteria,4DJ6S@85008|Micromonosporales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158343_k127_1302352_50	757424.Hsero_2412	3.143e-09	67.0	COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_1302352_28	1297863.APJF01000010_gene3372	2.803e-44	166.0	COG0346@1|root,COG0346@2|Bacteria,1NA4J@1224|Proteobacteria,2VE9U@28211|Alphaproteobacteria,3K1XE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158343_k127_1302352_19	1121448.DGI_3412	6.079e-64	229.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2M9TD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158343_k127_1302352_4	661478.OP10G_1484	5.947e-129	416.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	xth	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158343_k127_1302352_42	1232666.JANE01000011_gene2046	1.096e-15	81.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli,4GZIG@90964|Staphylococcaceae	91061|Bacilli	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
SRR25158343_k127_1302352_61	69014.TK1886	0.0008502	50.0	COG0063@1|root,arCOG00018@2157|Archaea,2XU4W@28890|Euryarchaeota,242WG@183968|Thermococci	183968|Thermococci	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158343_k127_1302352_45	158787.BSCA_0032	6.365e-12	78.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158343_k127_1302352_56	1123386.AUIW01000015_gene560	0.0003116	53.0	COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
SRR25158343_k127_1302352_32	517418.Ctha_0623	2.927e-38	151.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158343_k127_1302352_8	552811.Dehly_0104	5.223e-109	369.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi,34D8Y@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158343_k127_1302352_15	1229517.AMFD01000027_gene540	3.956e-70	254.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158343_k127_1302352_31	326427.Cagg_0647	1.71e-38	162.0	COG0745@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,EAL,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158343_k127_1302352_39	1120978.KB894081_gene222	6.401e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,27FKB@186828|Carnobacteriaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1302352_49	469371.Tbis_0228	1.518e-09	66.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4E3G7@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_1302352_47	653733.Selin_1933	1.153e-11	70.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	umuD	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,Peptidase_S24
SRR25158343_k127_1302352_10	882.DVU_2906	5.266e-93	322.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NJ4@68525|delta/epsilon subdivisions,2WJXN@28221|Deltaproteobacteria,2M84T@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	umuC	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
SRR25158343_k127_1302352_29	631362.Thi970DRAFT_01680	2.119e-43	168.0	COG4122@1|root,COG4122@2|Bacteria,1N5R0@1224|Proteobacteria,1SHSR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
SRR25158343_k127_1302352_3	269800.Tfu_2779	4.724e-158	513.0	COG0520@1|root,COG0520@2|Bacteria,2IAKT@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158343_k127_1302352_37	888439.HMPREF9240_00772	2.015e-24	111.0	COG0009@1|root,COG2890@1|root,COG0009@2|Bacteria,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4D3I7@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
SRR25158343_k127_1302352_53	742159.HMPREF0004_1936	4.13e-05	53.0	COG0454@1|root,COG1214@1|root,COG0456@2|Bacteria,COG1214@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,3T2RU@506|Alcaligenaceae	28216|Betaproteobacteria	KO	Acetyltransferase	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158343_k127_1302352_46	1121920.AUAU01000005_gene1110	1.083e-11	78.0	COG3227@1|root,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.4.24.27	ko:K08603,ko:K20273	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
SRR25158343_k127_1302352_33	981369.JQMJ01000004_gene394	2.656e-35	153.0	COG5297@1|root,COG5297@2|Bacteria,2GK92@201174|Actinobacteria,2NHEI@228398|Streptacidiphilus	201174|Actinobacteria	G	Glycosyl hydrolases family 6	guxA1	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CBM_3,Glyco_hydro_6,fn3
SRR25158343_k127_1302352_51	485913.Krac_8476	2.806e-07	58.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158343_k127_1302352_57	1219077.VAZ01S_050_00430	0.000404	47.0	2AKIJ@1|root,31BAK@2|Bacteria,1Q747@1224|Proteobacteria,1THZ6@1236|Gammaproteobacteria,1XXZ2@135623|Vibrionales	135623|Vibrionales	-	-	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0042802,GO:0044425	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv
SRR25158343_k127_1302982_3	1173027.Mic7113_3977	1.047e-73	252.0	2EXMF@1|root,33QXB@2|Bacteria,1GC4N@1117|Cyanobacteria,1HEDY@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1302982_10	743722.Sph21_3555	7.127e-08	65.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IVF4@117747|Sphingobacteriia	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1302982_9	1459636.NTE_03024	3.287e-10	68.0	COG1430@1|root,arCOG03116@2157|Archaea	2157|Archaea	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158343_k127_1302982_2	153721.MYP_1065	3.487e-95	320.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,47KJX@768503|Cytophagia	976|Bacteroidetes	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
SRR25158343_k127_1302982_5	906888.JCM19314_3024	1.107e-25	111.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,1I2N1@117743|Flavobacteriia,3HKFB@363408|Nonlabens	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
SRR25158343_k127_1302982_6	1454004.AW11_00337	2.807e-14	85.0	COG0439@1|root,COG0439@2|Bacteria,1R5XW@1224|Proteobacteria	1224|Proteobacteria	I	Biotin carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
SRR25158343_k127_1302982_7	1463861.JNXE01000001_gene5092	5.66e-11	74.0	2E8R3@1|root,33322@2|Bacteria,2I97P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1302982_1	1476973.JMMB01000007_gene2674	7.339e-102	343.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25QX8@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158343_k127_1302982_0	744872.Spica_2740	1.039e-240	760.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158343_k127_1302982_11	319003.Bra1253DRAFT_07113	7.4e-05	53.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2TUGK@28211|Alphaproteobacteria,3JRNV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158343_k127_1302982_4	57918.XP_004309588.1	4.413e-26	117.0	COG0194@1|root,KOG0707@2759|Eukaryota,37QQK@33090|Viridiplantae,3GDEC@35493|Streptophyta,4JGVS@91835|fabids	35493|Streptophyta	F	Guanylate kinase	AGK2	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006185,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009141,GO:0009144,GO:0009150,GO:0009151,GO:0009152,GO:0009153,GO:0009161,GO:0009162,GO:0009163,GO:0009165,GO:0009167,GO:0009170,GO:0009179,GO:0009180,GO:0009182,GO:0009183,GO:0009185,GO:0009186,GO:0009188,GO:0009189,GO:0009199,GO:0009200,GO:0009205,GO:0009215,GO:0009225,GO:0009259,GO:0009260,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015031,GO:0015833,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019673,GO:0019692,GO:0019693,GO:0032501,GO:0032502,GO:0033036,GO:0034404,GO:0034436,GO:0034641,GO:0034654,GO:0040008,GO:0042278,GO:0042451,GO:0042455,GO:0042886,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046034,GO:0046037,GO:0046054,GO:0046060,GO:0046066,GO:0046128,GO:0046129,GO:0046385,GO:0046390,GO:0046483,GO:0046710,GO:0046711,GO:0046939,GO:0046940,GO:0048229,GO:0048638,GO:0048856,GO:0050145,GO:0050789,GO:0050793,GO:0051179,GO:0051234,GO:0055086,GO:0065007,GO:0071702,GO:0071704,GO:0071705,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901264,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158343_k127_1302982_8	430498.S8BCW2	7.459e-11	71.0	COG0194@1|root,COG5055@1|root,KOG0707@2759|Eukaryota,KOG4141@2759|Eukaryota,38FKZ@33154|Opisthokonta,3P1VP@4751|Fungi,3QU73@4890|Ascomycota	4751|Fungi	F	Guanylate kinase	GUK1	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046710,GO:0046711,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158343_k127_1315966_1	511051.CSE_10260	4.729e-65	237.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158343_k127_1315966_0	1382356.JQMP01000003_gene1994	9.18e-117	385.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158343_k127_1340216_1	326426.Bbr_0236	1.857e-48	194.0	COG2367@1|root,COG2367@2|Bacteria,2HZMP@201174|Actinobacteria,4D0YE@85004|Bifidobacteriales	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158343_k127_1340216_2	932678.THERU_01550	1.067e-45	174.0	COG1189@1|root,COG1189@2|Bacteria,2G3MN@200783|Aquificae	200783|Aquificae	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158343_k127_1340216_5	1128427.KB904821_gene949	2.326e-16	87.0	COG1926@1|root,COG1926@2|Bacteria,1G2IS@1117|Cyanobacteria,1H9WZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158343_k127_1340216_6	391596.PBAL39_25470	1.339e-12	76.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_1340216_7	1450525.JATV01000009_gene775	1.209e-06	58.0	2DF54@1|root,32U4N@2|Bacteria,4NWS7@976|Bacteroidetes,1I9NX@117743|Flavobacteriia	976|Bacteroidetes	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_3
SRR25158343_k127_1340216_0	446462.Amir_0736	1.636e-135	440.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4DYTA@85010|Pseudonocardiales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158343_k127_1340216_8	555779.Dthio_PD2627	0.0005712	47.0	2BM0F@1|root,32FHC@2|Bacteria,1P0SE@1224|Proteobacteria,431Z7@68525|delta/epsilon subdivisions,2WX5P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1340216_3	671143.DAMO_0814	1.391e-25	111.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158343_k127_1340216_4	1353529.M899_1584	2.654e-17	96.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,430W9@68525|delta/epsilon subdivisions,2MSZJ@213481|Bdellovibrionales,2WW2T@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
SRR25158343_k127_1377104_7	1123252.ATZF01000001_gene1239	1.889e-56	203.0	COG1695@1|root,COG1695@2|Bacteria,1TTSG@1239|Firmicutes,4INFV@91061|Bacilli,27CWE@186824|Thermoactinomycetaceae	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158343_k127_1377104_2	234621.RER_04220	1.538e-108	358.0	COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158343_k127_1377104_6	1197906.CAJQ02000041_gene4883	1.486e-69	245.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,3K4FA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158343_k127_1377104_13	1089439.KB902239_gene506	2.976e-05	46.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1377104_11	760142.Hipma_0827	3.46e-09	61.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1377104_0	459495.SPLC1_S050840	2.342e-158	505.0	COG0863@1|root,COG0863@2|Bacteria,1G3H1@1117|Cyanobacteria,1H9NU@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158343_k127_1377104_4	592316.Pat9b_3314	4.922e-90	304.0	2C2MK@1|root,2Z81Z@2|Bacteria,1R391@1224|Proteobacteria,1S1QP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Restriction endonuclease NotI	-	-	-	-	-	-	-	-	-	-	-	-	NotI
SRR25158343_k127_1377104_12	880072.Desac_1068	1.063e-05	51.0	COG2336@1|root,COG2336@2|Bacteria,1N7YN@1224|Proteobacteria,42VFV@68525|delta/epsilon subdivisions,2WRSX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
SRR25158343_k127_1377104_10	323259.Mhun_2566	3.146e-19	91.0	arCOG03403@1|root,arCOG03403@2157|Archaea,2Y5T8@28890|Euryarchaeota	28890|Euryarchaeota	K	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158343_k127_1377104_3	1123320.KB889705_gene9337	1.395e-91	325.0	2B3XC@1|root,31WMA@2|Bacteria,2IDGX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_30C
SRR25158343_k127_1377104_5	247490.KSU1_D0192	4.902e-83	285.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	hprA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158343_k127_1377104_9	1219049.SP5_067_00040	2.042e-35	147.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,2UCGF@28211|Alphaproteobacteria,2K3QZ@204457|Sphingomonadales	204457|Sphingomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_1377104_8	1144275.COCOR_02140	1.06e-45	186.0	COG1749@1|root,COG1749@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4082,Flg_bb_rod,Flg_bbr_C
SRR25158343_k127_1377104_1	1380346.JNIH01000022_gene4001	3.138e-110	378.0	COG3409@1|root,COG3409@2|Bacteria,2I30G@201174|Actinobacteria	201174|Actinobacteria	M	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan	csn	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_46
SRR25158343_k127_1379499_8	760142.Hipma_0827	6.426e-39	165.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1379499_9	456442.Mboo_0081	1.264e-36	143.0	COG2003@1|root,arCOG04919@2157|Archaea,2XY1U@28890|Euryarchaeota,2N9SM@224756|Methanomicrobia	224756|Methanomicrobia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158343_k127_1379499_18	762982.HMPREF9442_02462	0.0002332	50.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	-	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	FdtA
SRR25158343_k127_1379499_4	1312959.KI914655_gene654	2.012e-66	235.0	28JJ5@1|root,2Z9C9@2|Bacteria,2HB8W@201174|Actinobacteria,1WAJT@1268|Micrococcaceae	201174|Actinobacteria	S	infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158343_k127_1379499_5	479434.Sthe_2331	5.829e-64	231.0	KOG2524@1|root,2ZJ84@2|Bacteria,2G826@200795|Chloroflexi,27XIS@189775|Thermomicrobia	189775|Thermomicrobia	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
SRR25158343_k127_1379499_11	350688.Clos_1283	1.274e-27	122.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158343_k127_1379499_16	345341.KUTG_04140	5.258e-05	49.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1379499_10	426117.M446_5320	1.373e-30	124.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,1JUVH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158343_k127_1379499_15	1227268.HMPREF1552_01678	5.57e-08	56.0	COG0291@1|root,COG0291@2|Bacteria,37B4G@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158343_k127_1379499_7	522373.Smlt3377	9.167e-44	165.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1X53K@135614|Xanthomonadales	135614|Xanthomonadales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158343_k127_1379499_2	1064535.MELS_1461	2.394e-119	400.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,4H1VZ@909932|Negativicutes	909932|Negativicutes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158343_k127_1379499_3	1047013.AQSP01000118_gene1252	4.302e-93	341.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1379499_0	857293.CAAU_1996	3.57e-239	755.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,36DYE@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158343_k127_1379499_1	698737.SLGD_02551	7.323e-218	692.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,4GX9Y@90964|Staphylococcaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158343_k127_1379499_6	515635.Dtur_1263	5.324e-57	206.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158343_k127_1379499_12	1348663.KCH_53960	9.51e-11	76.0	COG3291@1|root,COG3291@2|Bacteria,2IDEY@201174|Actinobacteria,2M4AZ@2063|Kitasatospora	201174|Actinobacteria	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR25158343_k127_1379499_13	1380408.AVGH01000044_gene1352	1.448e-09	60.0	2DSQW@1|root,33H3S@2|Bacteria,1VP4J@1239|Firmicutes,4HSVH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1394969_0	1382306.JNIM01000001_gene1792	4.918e-47	192.0	COG0557@1|root,COG0557@2|Bacteria	2|Bacteria	K	exoribonuclease II activity	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,dsrm
SRR25158343_k127_1426752_10	1122963.AUHB01000001_gene461	5.564e-06	56.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,2U4V0@28211|Alphaproteobacteria,36Z3J@31993|Methylocystaceae	28211|Alphaproteobacteria	FH	NUDIX domain	-	-	2.7.7.1	ko:K13522	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NUDIX
SRR25158343_k127_1426752_5	1250005.PHEL85_0096	7.044e-23	105.0	COG1443@1|root,COG1443@2|Bacteria,4NRS2@976|Bacteroidetes,1I2UY@117743|Flavobacteriia,3VVFE@52959|Polaribacter	976|Bacteroidetes	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1426752_1	391615.ABSJ01000005_gene583	1.515e-63	227.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1J4DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158343_k127_1426752_9	381666.H16_A3223	8.101e-08	65.0	COG0367@1|root,COG0367@2|Bacteria,1N44T@1224|Proteobacteria,2W4WT@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	-
SRR25158343_k127_1426752_2	760568.Desku_1910	4.318e-52	198.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,26079@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM peptidase T-like protein	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158343_k127_1426752_8	637910.ROD_48381	7.705e-09	61.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RRSU@1236|Gammaproteobacteria,3WXGV@544|Citrobacter	1236|Gammaproteobacteria	C	Malate/L-lactate dehydrogenase	comC	-	1.1.1.338,1.5.1.21	ko:K13609,ko:K16844	ko00270,ko00310,ko00960,ko01100,ko01120,map00270,map00310,map00960,map01100,map01120	-	R02203,R07137	RC00031,RC00135	ko00000,ko00001,ko01000	-	-	-	Ldh_2
SRR25158343_k127_1426752_3	272623.L36841	9.57e-48	179.0	COG3382@1|root,COG3382@2|Bacteria,1TT38@1239|Firmicutes,4HCE2@91061|Bacilli,1YCDG@1357|Lactococcus	91061|Bacilli	K	B3/4 domain	XK27_07210	-	-	-	-	-	-	-	-	-	-	-	B3_4
SRR25158343_k127_1426752_6	13616.ENSMODP00000015272	2.181e-11	68.0	COG1011@1|root,COG3173@1|root,KOG1469@2759|Eukaryota,KOG3085@2759|Eukaryota,38BWX@33154|Opisthokonta,3BDYX@33208|Metazoa,3CUUN@33213|Bilateria,48ABS@7711|Chordata,4933E@7742|Vertebrata,3JAB2@40674|Mammalia,4JZ9V@9263|Metatheria	33208|Metazoa	I	acyl-CoA dehydrogenase family, member 10	ACAD10	GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K11729	-	-	-	-	ko00000	-	-	-	APH,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,HAD_2,Hydrolase
SRR25158343_k127_1426752_0	1211815.CBYP010000024_gene1562	1.199e-89	298.0	COG2133@1|root,COG3291@1|root,COG5479@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG5479@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,LGFP,PKD
SRR25158343_k127_1478463_0	1229780.BN381_80336	3.904e-62	224.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,3UWDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158343_k127_1478463_1	945713.IALB_0186	6.792e-08	66.0	COG4675@1|root,COG5276@1|root,COG4675@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Collar,Phage_fiber_2
SRR25158343_k127_1492270_22	80637.XP_007767174.1	2.864e-11	72.0	COG0500@1|root,KOG1269@2759|Eukaryota,3A1WA@33154|Opisthokonta,3P2Y5@4751|Fungi	4751|Fungi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158343_k127_1492270_16	1500259.JQLD01000009_gene1737	1.137e-15	81.0	COG2361@1|root,COG2361@2|Bacteria,1RAGS@1224|Proteobacteria,2UFCR@28211|Alphaproteobacteria,4BFV5@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158343_k127_1492270_19	767029.HMPREF9154_0160	2.367e-12	70.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_3,NTP_transf_2
SRR25158343_k127_1492270_17	1294143.H681_21650	3.21e-15	83.0	COG1443@1|root,COG1443@2|Bacteria,1P8AM@1224|Proteobacteria,1RQA3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	NUDIX hydrolase	yfcD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0565	NUDIX
SRR25158343_k127_1492270_12	525379.HMPREF0819_0968	2.659e-24	108.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli	91061|Bacilli	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158343_k127_1492270_14	1299327.I546_2367	3.079e-17	92.0	COG1216@1|root,COG1216@2|Bacteria,2I9Y7@201174|Actinobacteria,233HM@1762|Mycobacteriaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158343_k127_1492270_26	1299327.I546_2367	4.449e-06	53.0	COG1216@1|root,COG1216@2|Bacteria,2I9Y7@201174|Actinobacteria,233HM@1762|Mycobacteriaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158343_k127_1492270_7	656519.Halsa_2307	1.578e-46	174.0	COG0500@1|root,COG2226@2|Bacteria,1V5ZN@1239|Firmicutes,25HYE@186801|Clostridia,3WBSF@53433|Halanaerobiales	186801|Clostridia	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1492270_5	269800.Tfu_1742	6.832e-51	191.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1492270_10	393480.FNP_1210	1.129e-31	130.0	COG2109@1|root,COG2109@2|Bacteria,37A5H@32066|Fusobacteria	32066|Fusobacteria	H	cob(I)yrinic acid a,c-diamide adenosyltransferase	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158343_k127_1492270_13	515635.Dtur_0034	3.133e-18	88.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	nrdH	-	-	ko:K03676,ko:K06191	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158343_k127_1492270_11	525904.Tter_0069	4.023e-29	126.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158343_k127_1492270_24	1504823.CCMM01000012_gene1810	2.3e-07	55.0	COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158343_k127_1492270_21	1280001.BAOA01000079_gene3046	1.019e-11	72.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XSI7@135623|Vibrionales	135623|Vibrionales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158343_k127_1492270_23	1121028.ARQE01000001_gene3518	1.937e-07	58.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,2PJWJ@255475|Aurantimonadaceae	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158343_k127_1492270_1	547144.HydHO_1009	3.189e-179	575.0	COG0056@1|root,COG0056@2|Bacteria,2G3IZ@200783|Aquificae	200783|Aquificae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158343_k127_1492270_4	637390.AFOH01000107_gene176	3.423e-53	198.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,2NCA1@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158343_k127_1492270_0	1230342.CTM_26657	1.369e-202	639.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,36ERS@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158343_k127_1492270_20	469610.HMPREF0189_00039	5.629e-12	73.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158343_k127_1492270_18	1220534.B655_0386	2.263e-14	81.0	COG0580@1|root,arCOG04431@2157|Archaea,2XT1N@28890|Euryarchaeota,23P3G@183925|Methanobacteria	183925|Methanobacteria	G	PFAM Major intrinsic protein	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
SRR25158343_k127_1492270_15	1150398.JIBJ01000002_gene920	7.242e-16	87.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria,1W8JM@1268|Micrococcaceae	201174|Actinobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	rhaD	-	1.1.1.1,1.1.1.140,4.1.2.19	ko:K00001,ko:K00068,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R05607,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short,adh_short_C2
SRR25158343_k127_1492270_2	1122605.KB893644_gene1305	6.851e-95	349.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158343_k127_1492270_6	546271.Selsp_2040	6.422e-47	185.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4H3UJ@909932|Negativicutes	909932|Negativicutes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_1492270_8	1517681.HW45_20275	3.95e-36	149.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XT3R@135623|Vibrionales	135623|Vibrionales	M	UTP--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158343_k127_1492270_3	1444711.CCJF01000004_gene2402	1.652e-71	263.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2JFFG@204428|Chlamydiae	204428|Chlamydiae	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158343_k127_1516216_34	1219049.SP5_067_00040	0.0001671	49.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,2UCGF@28211|Alphaproteobacteria,2K3QZ@204457|Sphingomonadales	204457|Sphingomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_1516216_20	1121007.AUML01000001_gene1309	1.651e-15	90.0	COG4076@1|root,COG4076@2|Bacteria,4NSG2@976|Bacteroidetes,1IK7G@117743|Flavobacteriia	976|Bacteroidetes	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PRMT5
SRR25158343_k127_1516216_31	111780.Sta7437_2886	1.183e-06	53.0	COG3041@1|root,COG3041@2|Bacteria,1G7V7@1117|Cyanobacteria,3VMW8@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Plasmid maintenance system killer protein	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
SRR25158343_k127_1516216_35	1120963.KB894491_gene1107	0.0002035	46.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1516216_13	1219049.SP5_067_00040	2.946e-40	162.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,2UCGF@28211|Alphaproteobacteria,2K3QZ@204457|Sphingomonadales	204457|Sphingomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_1516216_8	574087.Acear_0203	4.23e-83	296.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia	186801|Clostridia	C	TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
SRR25158343_k127_1516216_22	1454202.PPBDW_100105___1	1.398e-12	71.0	COG0494@1|root,COG0494@2|Bacteria,1MZB8@1224|Proteobacteria,1SAAF@1236|Gammaproteobacteria,1Y3AE@135623|Vibrionales	135623|Vibrionales	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1516216_30	1280001.BAOA01000022_gene610	1.164e-06	53.0	COG0494@1|root,COG0494@2|Bacteria,1MZB8@1224|Proteobacteria,1SAAF@1236|Gammaproteobacteria,1Y3AE@135623|Vibrionales	135623|Vibrionales	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1516216_26	1123308.KB904559_gene1395	4.907e-08	63.0	COG0546@1|root,COG0546@2|Bacteria,1UYBR@1239|Firmicutes,4HZ8W@91061|Bacilli	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158343_k127_1516216_33	591158.SSMG_02629	4.305e-05	55.0	COG2755@1|root,COG2755@2|Bacteria,2GY4B@201174|Actinobacteria	201174|Actinobacteria	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRR25158343_k127_1516216_28	240015.ACP_0598	6.091e-08	59.0	2E8K6@1|root,332XV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1516216_14	1121430.JMLG01000001_gene2061	2.395e-28	118.0	COG5573@1|root,COG5573@2|Bacteria,1V7GS@1239|Firmicutes,24JFR@186801|Clostridia,2655B@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158343_k127_1516216_17	1444712.BN1013_01163	1.734e-19	96.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158343_k127_1516216_27	106370.Francci3_0878	5.188e-08	61.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4EU5A@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158343_k127_1516216_9	436229.JOEH01000030_gene4823	2.622e-75	260.0	2C4WQ@1|root,2ZB7D@2|Bacteria,2IAGK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1516216_6	67267.JNXT01000041_gene5581	5.187e-90	322.0	2BN9U@1|root,32GXB@2|Bacteria,2GN9A@201174|Actinobacteria	201174|Actinobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158343_k127_1516216_16	298655.KI912266_gene6443	1.495e-19	93.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_1516216_23	345341.KUTG_02545	8.426e-09	66.0	28HJF@1|root,337ZK@2|Bacteria,2IGKB@201174|Actinobacteria,4E7Z5@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Vps62
SRR25158343_k127_1516216_12	479434.Sthe_1249	6.841e-61	232.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158343_k127_1516216_25	471856.Jden_2469	3.353e-08	60.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158343_k127_1516216_10	401526.TcarDRAFT_2701	2.219e-63	229.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4H2HK@909932|Negativicutes	909932|Negativicutes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C,AdoHcyase_NAD
SRR25158343_k127_1516216_21	877421.AUJT01000003_gene3161	3.632e-13	80.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,27J9M@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158343_k127_1516216_15	675635.Psed_0380	1.434e-19	100.0	COG0189@1|root,COG0189@2|Bacteria,2HUCI@201174|Actinobacteria,4E25P@85010|Pseudonocardiales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1516216_11	315730.BcerKBAB4_1764	3.836e-63	233.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HDM0@91061|Bacilli,1ZDXU@1386|Bacillus	91061|Bacilli	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158343_k127_1516216_3	2002.JOEQ01000077_gene4088	2.484e-122	405.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4EHDN@85012|Streptosporangiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158343_k127_1516216_29	504728.K649_00235	1.094e-06	59.0	COG0560@1|root,COG0560@2|Bacteria,1WKQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
SRR25158343_k127_1516216_7	1123250.KB908412_gene2128	7.179e-90	314.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H2IU@909932|Negativicutes	909932|Negativicutes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158343_k127_1516216_5	391009.Tmel_1578	2.598e-93	320.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GC4M@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158343_k127_1516216_0	1233951.IO90_05685	2.433e-177	569.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia,3HHBQ@358033|Chryseobacterium	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158343_k127_1516216_18	1121022.ABENE_03565	5.584e-19	97.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,2KGBS@204458|Caulobacterales	204458|Caulobacterales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158343_k127_1516216_2	762948.HMPREF0733_10457	1.828e-123	402.0	COG1054@1|root,COG1054@2|Bacteria,2GMMP@201174|Actinobacteria,1W8JF@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
SRR25158343_k127_1516216_1	1042156.CXIVA_03500	2.66e-135	451.0	COG5265@1|root,COG5265@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147,ko:K12531	ko02020,map02020	M00326	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1516216_4	326424.FRAAL6509	7.406e-119	396.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERP6@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1521913_0	118166.JH976537_gene394	5.746e-157	497.0	COG3293@1|root,COG3293@2|Bacteria,1FZVT@1117|Cyanobacteria,1HDEX@1150|Oscillatoriales	1117|Cyanobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158343_k127_1521913_1	118166.JH976537_gene967	1.82e-11	64.0	28PZ7@1|root,2ZCIP@2|Bacteria,1G54I@1117|Cyanobacteria,1HAKF@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1527589_5	946235.CAER01000044_gene1839	1.892e-11	65.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,23KIN@182709|Oceanobacillus	91061|Bacilli	U	Signal peptidase, peptidase S26	spsB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158343_k127_1527589_1	688246.Premu_2583	3.113e-56	207.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158343_k127_1527589_0	1120985.AUMI01000016_gene1983	4.097e-80	275.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H331@909932|Negativicutes	909932|Negativicutes	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158343_k127_1527589_4	1246.JMEA01000006_gene63	2.886e-19	91.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,4AXZW@81850|Leuconostocaceae	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158343_k127_1527589_3	1265503.KB905163_gene2277	4.425e-26	126.0	COG3420@1|root,COG5306@1|root,COG3420@2|Bacteria,COG5306@2|Bacteria,1NGRY@1224|Proteobacteria,1T22S@1236|Gammaproteobacteria,2Q81Z@267889|Colwelliaceae	1236|Gammaproteobacteria	P	Pentaxin family	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	CUB,Laminin_G_3
SRR25158343_k127_1527589_2	68170.KL590490_gene1265	6.958e-27	128.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
SRR25158343_k127_1527589_6	1538295.JY96_16965	5.841e-06	60.0	COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
SRR25158343_k127_1594782_0	526227.Mesil_0007	4.52e-70	248.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158343_k127_1628540_7	1246995.AFR_28820	5.156e-05	53.0	COG1277@1|root,COG1277@2|Bacteria,2GMJD@201174|Actinobacteria,4DE12@85008|Micromonosporales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1628540_0	1120950.KB892751_gene6769	1.971e-97	327.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4DPR9@85009|Propionibacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1628540_4	1234593.ANBY01000040_gene813	2.652e-86	295.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,4GX35@90964|Staphylococcaceae	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158343_k127_1628540_1	1227261.HMPREF0043_01904	1.388e-96	329.0	COG0842@1|root,COG0842@2|Bacteria,2IB08@201174|Actinobacteria,4D4NV@85005|Actinomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158343_k127_1628540_2	1227261.HMPREF0043_01903	6.531e-95	317.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4D63Y@85005|Actinomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1628540_6	1306947.ARQD01000004_gene163	4.753e-09	60.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1628540_5	1198452.Jab_1c10470	1.181e-11	73.0	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1628540_3	1408321.JNJD01000012_gene2287	2.178e-93	322.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,27IH7@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_1702253_0	583355.Caka_1808	2.123e-97	331.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,3K7IM@414999|Opitutae	414999|Opitutae	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158343_k127_1702253_1	518766.Rmar_1101	7.146e-50	179.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1FIS2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_1765570_12	1122986.KB908322_gene1064	7.915e-24	111.0	COG0546@1|root,COG0546@2|Bacteria,4NMPP@976|Bacteroidetes,2FS95@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158343_k127_1765570_10	1380386.JIAW01000001_gene4730	2.461e-28	117.0	COG2315@1|root,COG2315@2|Bacteria,2IHRR@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158343_k127_1765570_5	1304284.L21TH_2076	4.693e-76	281.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,36FK8@31979|Clostridiaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158343_k127_1765570_2	871963.Desdi_2932	3.007e-111	371.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,260A0@186807|Peptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_1765570_15	2903.EOD27628	5.02e-17	88.0	KOG1584@1|root,KOG1584@2759|Eukaryota	2759|Eukaryota	S	sulfotransferase activity	St1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006805,GO:0006950,GO:0006952,GO:0008146,GO:0008150,GO:0008152,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016740,GO:0016782,GO:0042221,GO:0042742,GO:0043207,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0051923,GO:0070887,GO:0071466,GO:0098542	2.8.2.1,2.8.2.4	ko:K01014,ko:K01016,ko:K01025	ko00140,ko05204,map00140,map05204	-	R01242,R02350	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
SRR25158343_k127_1765570_8	673860.AciM339_1453	3.024e-47	184.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,3F2QZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Polyprenyl synthetase	idsA	GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158343_k127_1765570_0	1075090.GOAMR_59_00440	1.852e-266	850.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4GCPV@85026|Gordoniaceae	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158343_k127_1765570_9	1382306.JNIM01000001_gene2840	2.189e-34	141.0	COG1131@1|root,COG1131@2|Bacteria,2G6KA@200795|Chloroflexi	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1765570_1	1226325.HMPREF1548_04427	9.784e-170	563.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,36EWE@31979|Clostridiaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158343_k127_1765570_4	66869.JNXG01000020_gene3518	1.478e-77	267.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,419EZ@629295|Streptomyces griseus group	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158343_k127_1765570_3	66869.JNXG01000020_gene3517	1.144e-108	360.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_1765570_14	446470.Snas_3297	1.751e-19	101.0	2EYG2@1|root,33RPY@2|Bacteria,2H34T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1765570_11	322159.STER_0336	4.93e-25	111.0	COG0499@1|root,COG1051@1|root,COG0499@2|Bacteria,COG1051@2|Bacteria,1V1P7@1239|Firmicutes,4HFQH@91061|Bacilli	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	AdoHcyase_NAD,NUDIX
SRR25158343_k127_1765570_18	398511.BpOF4_12475	1.168e-06	60.0	COG3173@1|root,COG3173@2|Bacteria,1U4B2@1239|Firmicutes,4HG90@91061|Bacilli,1ZDFU@1386|Bacillus	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	APH
SRR25158343_k127_1765570_16	716928.AJQT01000023_gene3692	2.482e-10	68.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158343_k127_1765570_6	1122147.AUEH01000047_gene2951	7.249e-66	235.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158343_k127_1765570_13	1227349.C170_24518	1.291e-21	106.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,26R6H@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158343_k127_1765570_17	1211035.CD30_10150	8.955e-10	64.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3IYGY@400634|Lysinibacillus	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158343_k127_1765570_19	1231336.L248_1855	3.964e-05	57.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae	91061|Bacilli	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_1765570_7	648996.Theam_0905	7.316e-54	197.0	COG0130@1|root,COG0130@2|Bacteria,2G40M@200783|Aquificae	200783|Aquificae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
SRR25158343_k127_1772019_16	1231057.AMGD01000003_gene2184	3.95e-07	62.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,26DNM@186818|Planococcaceae	91061|Bacilli	M	Mechanosensitive ion channel family protein	ykuT	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158343_k127_1772019_12	28444.JODQ01000008_gene1197	4.998e-26	119.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4EHD3@85012|Streptosporangiales	201174|Actinobacteria	I	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158343_k127_1772019_9	1033730.CAHG01000016_gene292	7.404e-41	168.0	COG1409@1|root,COG5479@1|root,COG1409@2|Bacteria,COG5479@2|Bacteria,2GMJR@201174|Actinobacteria,4DRUQ@85009|Propionibacteriales	201174|Actinobacteria	M	Protein of unknown function (DUF3152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3152
SRR25158343_k127_1772019_13	1027396.LMOSA_1350	1.992e-15	87.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,26IRZ@186820|Listeriaceae	91061|Bacilli	K	LysR family	cysL	-	-	ko:K21900	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158343_k127_1772019_0	1047013.AQSP01000113_gene747	5.503e-150	482.0	COG1260@1|root,COG1260@2|Bacteria,2NNVE@2323|unclassified Bacteria	2|Bacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158343_k127_1772019_18	339860.Msp_1329	0.0002709	52.0	COG0483@1|root,arCOG01349@2157|Archaea,2Y87S@28890|Euryarchaeota,23PI8@183925|Methanobacteria	183925|Methanobacteria	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158343_k127_1772019_11	1382304.JNIL01000001_gene2067	7.873e-27	116.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,279S1@186823|Alicyclobacillaceae	91061|Bacilli	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158343_k127_1772019_7	2002.JOEQ01000038_gene4160	1.35e-65	237.0	COG0025@1|root,COG0025@2|Bacteria,2ICJV@201174|Actinobacteria	201174|Actinobacteria	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158343_k127_1772019_5	211114.JOEF01000002_gene4350	2.293e-75	275.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DZQT@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158343_k127_1772019_2	926550.CLDAP_09540	3.36e-141	460.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2G5XF@200795|Chloroflexi	2|Bacteria	L	PFAM UvrD REP helicase	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
SRR25158343_k127_1772019_4	926550.CLDAP_15930	3.205e-84	291.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158343_k127_1772019_1	1121396.KB893087_gene375	1.627e-149	499.0	COG1555@1|root,COG1555@2|Bacteria,1R9RS@1224|Proteobacteria	1224|Proteobacteria	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1772019_17	1122214.AQWH01000008_gene1547	7.468e-06	57.0	COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U12U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158343_k127_1772019_6	357808.RoseRS_0010	9.048e-71	256.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158343_k127_1772019_14	68194.JNXR01000001_gene6784	2.468e-10	73.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_1772019_15	1118235.CAJH01000024_gene1747	5.275e-08	62.0	COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria,1SCTX@1236|Gammaproteobacteria,1X6HK@135614|Xanthomonadales	135614|Xanthomonadales	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1772019_10	1151061.CAJY01000017_gene253	3.011e-30	127.0	COG1309@1|root,COG1309@2|Bacteria,2INBA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158343_k127_1772019_3	1501230.ET33_12970	1.858e-117	390.0	COG0654@1|root,COG0654@2|Bacteria,1V1VT@1239|Firmicutes,4HFX4@91061|Bacilli,26V4M@186822|Paenibacillaceae	91061|Bacilli	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158343_k127_1772019_8	1254432.SCE1572_21555	3.589e-54	196.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,439GU@68525|delta/epsilon subdivisions,2X4SU@28221|Deltaproteobacteria,2YZIQ@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158343_k127_1777918_9	1262914.BN533_01446	2.698e-23	112.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes,4H3UP@909932|Negativicutes	909932|Negativicutes	NU	Type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158343_k127_1777918_13	1121428.DESHY_60062___1	1.683e-06	61.0	COG2165@1|root,COG2165@2|Bacteria,1W5JZ@1239|Firmicutes,256FM@186801|Clostridia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158343_k127_1777918_12	1131462.DCF50_p2049	1.418e-06	56.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,25EY6@186801|Clostridia,263DH@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
SRR25158343_k127_1777918_3	42256.RradSPS_0863	1.94e-83	293.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158343_k127_1777918_2	635013.TherJR_1754	3.231e-121	411.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,2603X@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158343_k127_1777918_17	1042209.HK44_026675	0.0008041	47.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158343_k127_1777918_5	1219049.SP5_067_00040	1.551e-45	177.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,2UCGF@28211|Alphaproteobacteria,2K3QZ@204457|Sphingomonadales	204457|Sphingomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_1777918_7	1232410.KI421413_gene633	3.234e-32	126.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,42QWQ@68525|delta/epsilon subdivisions,2WMRI@28221|Deltaproteobacteria,43T93@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1777918_8	1120705.FG95_03711	2.581e-25	106.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,2U6KV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1777918_10	926564.KI911641_gene2204	5.557e-15	78.0	2965V@1|root,2ZTG1@2|Bacteria,2HAT5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1777918_4	1120950.KB892765_gene5685	4.016e-50	190.0	COG3173@1|root,COG3173@2|Bacteria,2IH8M@201174|Actinobacteria,4DUHM@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158343_k127_1777918_6	1116232.AHBF01000021_gene3452	2.622e-36	149.0	COG0189@1|root,COG0189@2|Bacteria,2I8TP@201174|Actinobacteria	201174|Actinobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1777918_0	1121939.L861_16525	0.0	3339.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Insecticidal toxin complex	tcaC	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SRR25158343_k127_1777918_1	1121939.L861_16530	8.428e-290	910.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	VRP1
SRR25158343_k127_1828376_38	1122164.JHWF01000017_gene503	5.25e-06	50.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1828376_36	644282.Deba_1392	2.557e-10	69.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1R7IR@1224|Proteobacteria,42MT7@68525|delta/epsilon subdivisions,2WITW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_1,TPR_14,TPR_2,TPR_8
SRR25158343_k127_1828376_34	386415.NT01CX_0759	6.34e-14	84.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,36DG8@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158343_k127_1828376_10	1321778.HMPREF1982_03264	1.852e-55	204.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,268HU@186813|unclassified Clostridiales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_1828376_5	273677.BW34_02430	2.534e-76	269.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4FKF2@85023|Microbacteriaceae	201174|Actinobacteria	J	tRNA synthetases class I (W and Y)	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158343_k127_1828376_17	1125718.HMPREF1318_2666	8.938e-43	172.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4D36A@85005|Actinomycetales	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158343_k127_1828376_26	573370.DMR_15350	7.835e-29	119.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2MBIE@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158343_k127_1828376_15	1322246.BN4_12726	1.616e-49	180.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MBR8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158343_k127_1828376_30	1242969.ATCC51562_1715	2.073e-25	111.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2YPKU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158343_k127_1828376_6	1194972.MVAC_07579	5.641e-68	242.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,2350J@1762|Mycobacteriaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158343_k127_1828376_13	331678.Cphamn1_2270	2.106e-51	188.0	COG0522@1|root,COG0522@2|Bacteria,1FDFW@1090|Chlorobi	1090|Chlorobi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158343_k127_1828376_22	877411.JMMA01000002_gene2729	2.448e-33	132.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158343_k127_1828376_20	926550.CLDAP_03860	8.833e-37	144.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158343_k127_1828376_39	1501268.EW14_1896	1.551e-05	48.0	COG0257@1|root,COG0257@2|Bacteria,1GRE2@1117|Cyanobacteria,1MP6X@1212|Prochloraceae	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158343_k127_1828376_27	1144664.F973_02477	9.122e-29	116.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,3NPBC@468|Moraxellaceae	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158343_k127_1828376_4	593907.Celgi_0836	2.368e-86	304.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4F0MV@85016|Cellulomonadaceae	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158343_k127_1828376_2	1713.JOFV01000008_gene3174	8.407e-157	507.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4F0FK@85016|Cellulomonadaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1828376_29	717606.PaecuDRAFT_1919	1.273e-26	114.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,26WST@186822|Paenibacillaceae	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158343_k127_1828376_19	944479.JQLX01000017_gene295	1.56e-39	156.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,2M6ZB@213113|Desulfurellales	28221|Deltaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158343_k127_1828376_28	1123263.AUKY01000019_gene1305	3.218e-27	114.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,3VQGV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158343_k127_1828376_8	1122602.ATXP01000001_gene913	1.01e-58	208.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,1W829@1268|Micrococcaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158343_k127_1828376_24	485913.Krac_12514	2.523e-31	127.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158343_k127_1828376_21	1123302.KB904166_gene638	1.605e-35	137.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli	91061|Bacilli	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158343_k127_1828376_9	596330.HMPREF0628_0304	9.484e-58	206.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,22G54@1570339|Peptoniphilaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158343_k127_1828376_25	1236976.JCM16418_4437	1.246e-29	121.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,26XQC@186822|Paenibacillaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158343_k127_1828376_14	441768.ACL_0097	1.772e-50	182.0	COG0093@1|root,COG0093@2|Bacteria,3WTN8@544448|Tenericutes	544448|Tenericutes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158343_k127_1828376_32	552396.HMPREF0863_02787	1.768e-17	88.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,3VR8U@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158343_k127_1828376_37	944481.JAFP01000001_gene1471	1.357e-06	52.0	COG0255@1|root,COG0255@2|Bacteria,1Q8ZW@1224|Proteobacteria,439UP@68525|delta/epsilon subdivisions,2X58C@28221|Deltaproteobacteria,2M7GU@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal L29 protein	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158343_k127_1828376_12	573061.Clocel_3726	3.831e-53	190.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,36E4K@31979|Clostridiaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158343_k127_1828376_7	498761.HM1_1384	1.507e-63	224.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158343_k127_1828376_31	938288.HG326226_gene681	8.224e-19	92.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,2695W@186813|unclassified Clostridiales	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158343_k127_1828376_23	504487.JCM19302_3153	4.274e-33	129.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158343_k127_1828376_3	1220589.CD32_05040	2.528e-94	316.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3IW55@400634|Lysinibacillus	91061|Bacilli	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158343_k127_1828376_35	751994.AGIG01000002_gene921	3.277e-12	71.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158343_k127_1828376_16	1089553.Tph_c25840	8.916e-43	165.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42ERX@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158343_k127_1828376_11	498761.HM1_1378	1.256e-54	198.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158343_k127_1828376_18	635013.TherJR_0295	1.967e-42	158.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158343_k127_1828376_1	336407.RBE_1064	5.282e-181	574.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,47EUU@766|Rickettsiales	766|Rickettsiales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_1828376_33	887898.HMPREF0551_1400	1.918e-17	85.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,1JZU8@119060|Burkholderiaceae	28216|Betaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,4.2.1.91,5.4.99.5	ko:K01713,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158343_k127_1828376_0	338966.Ppro_0677	1.102e-271	852.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,43SV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_1829704_5	56107.Cylst_4409	2.42e-81	284.0	2EIH2@1|root,33PXJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1829704_25	1125779.HMPREF1219_01713	9.252e-06	51.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158343_k127_1829704_26	1184609.KILIM_033_00530	2.399e-05	50.0	COG2002@1|root,COG2002@2|Bacteria,2GWQF@201174|Actinobacteria	201174|Actinobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158343_k127_1829704_22	1312959.KI914681_gene2003	2.187e-09	64.0	COG5611@1|root,COG5611@2|Bacteria,2GUMH@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158343_k127_1829704_14	1444712.BN1013_02355	2.595e-30	125.0	COG0537@1|root,COG0537@2|Bacteria,2JG1P@204428|Chlamydiae	204428|Chlamydiae	FG	trans-aconitate 2-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158343_k127_1829704_23	1150469.RSPPHO_02782	2.418e-07	56.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K10297	-	-	-	-	ko00000,ko04121	-	-	-	Beta_helix,SLH,TIR_2
SRR25158343_k127_1829704_24	1120949.KB903339_gene7883	2.199e-06	53.0	COG1051@1|root,COG1051@2|Bacteria,2IIHF@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1829704_10	1001240.GY21_13000	3.432e-39	153.0	COG1576@1|root,COG1576@2|Bacteria,2HFEZ@201174|Actinobacteria,4FP0J@85023|Microbacteriaceae	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1829704_28	471852.Tcur_4375	0.0001577	53.0	COG1426@1|root,COG1426@2|Bacteria,2IQH6@201174|Actinobacteria,4EQ5P@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158343_k127_1829704_27	941770.GL622178_gene99	8.898e-05	53.0	COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4HHZ7@91061|Bacilli,3FCA2@33958|Lactobacillaceae	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158343_k127_1829704_0	1120972.AUMH01000003_gene2909	3.394e-193	631.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,2783N@186823|Alicyclobacillaceae	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158343_k127_1829704_2	309801.trd_0177	9.322e-98	331.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia	189775|Thermomicrobia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158343_k127_1829704_3	1128421.JAGA01000002_gene1414	2.9e-94	325.0	COG0769@1|root,COG0769@2|Bacteria,2NNZM@2323|unclassified Bacteria	2|Bacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_1829704_17	910964.GEAM_4144	1.752e-21	99.0	COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,1S44A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	belongs to the nudix hydrolase family	rppH_2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158343_k127_1829704_4	313589.JNB_10919	1.957e-91	309.0	COG1834@1|root,COG1834@2|Bacteria,2I0JX@201174|Actinobacteria,4FIA5@85021|Intrasporangiaceae	201174|Actinobacteria	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158343_k127_1829704_18	1120951.AUBG01000012_gene1641	1.291e-13	73.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158343_k127_1829704_1	1121428.DESHY_160190___1	3.316e-167	541.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2611G@186807|Peptococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158343_k127_1829704_12	573413.Spirs_1140	1.85e-33	143.0	COG0805@1|root,COG0805@2|Bacteria	2|Bacteria	U	protein transport	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158343_k127_1829704_21	1122223.KB890696_gene488	2.131e-09	61.0	COG1826@1|root,COG1826@2|Bacteria,1WKJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158343_k127_1829704_19	561175.KB894093_gene3997	2.805e-10	68.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria	201174|Actinobacteria	M	Sortase (surface protein transpeptidase)	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158343_k127_1829704_8	1379698.RBG1_1C00001G1620	2.366e-55	207.0	COG2222@1|root,COG2222@2|Bacteria,2NQVV@2323|unclassified Bacteria	2|Bacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	pgi	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRR25158343_k127_1829704_16	1144275.COCOR_04539	1.354e-22	103.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_1829704_7	1268237.G114_16330	9.651e-56	202.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07660	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1829704_11	1128427.KB904821_gene1193	8.458e-34	143.0	COG5002@1|root,COG5002@2|Bacteria,1G236@1117|Cyanobacteria,1H8UW@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158343_k127_1829704_15	1443665.JACA01000003_gene940	4.694e-25	113.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,1I2B0@117743|Flavobacteriia,2YHB3@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
SRR25158343_k127_1829704_6	926562.Oweho_0708	3.352e-73	267.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia,2PAKF@246874|Cryomorphaceae	976|Bacteroidetes	J	Arginyl tRNA synthetase N terminal domain	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158343_k127_1829704_20	452652.KSE_16480	8.84e-10	66.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,2M2W5@2063|Kitasatospora	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158343_k127_1829704_9	888050.HMPREF9004_0735	3.655e-50	182.0	COG0229@1|root,COG0229@2|Bacteria,2IIHB@201174|Actinobacteria,4D857@85005|Actinomycetales	201174|Actinobacteria	O	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158343_k127_1829704_13	264462.Bd1346	6.399e-33	134.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,42W1X@68525|delta/epsilon subdivisions,2MTXK@213481|Bdellovibrionales,2WRUK@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158343_k127_1831314_12	879305.HMPREF9290_0300	3.199e-32	131.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,22G6R@1570339|Peptoniphilaceae	186801|Clostridia	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158343_k127_1831314_6	553184.ATORI0001_0239	4.001e-96	327.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CVG1@84998|Coriobacteriia	84998|Coriobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158343_k127_1831314_21	1499967.BAYZ01000080_gene910	0.0001577	53.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,ESPR,LVIVD,YadA_anchor,YadA_head,YadA_stalk
SRR25158343_k127_1831314_7	1280671.AUJH01000002_gene1799	8.169e-89	310.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,4BWJF@830|Butyrivibrio	186801|Clostridia	C	ATP synthase alpha/beta chain, C terminal domain	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
SRR25158343_k127_1831314_18	1178540.BA70_10670	1.829e-10	71.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
SRR25158343_k127_1831314_2	1410622.JNKY01000010_gene1155	6.553e-114	381.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,27IDF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158343_k127_1831314_19	999411.HMPREF1092_03006	2.74e-07	56.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,36MZ0@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
SRR25158343_k127_1831314_20	1306174.JODP01000001_gene5090	2.392e-05	56.0	COG1470@1|root,COG1470@2|Bacteria,2I2TR@201174|Actinobacteria	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF916
SRR25158343_k127_1831314_4	1504822.CCNO01000015_gene584	4.555e-107	357.0	COG0482@1|root,COG0482@2|Bacteria,2NNPW@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158343_k127_1831314_1	479431.Namu_5171	1.282e-188	609.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4ERRJ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158343_k127_1831314_8	1382306.JNIM01000001_gene244	6.641e-84	295.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
SRR25158343_k127_1831314_14	1521187.JPIM01000030_gene1516	3.143e-19	93.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,375V0@32061|Chloroflexia	32061|Chloroflexia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158343_k127_1831314_9	635013.TherJR_1896	4.935e-51	196.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,260MF@186807|Peptococcaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158343_k127_1831314_13	1141106.CAIB01000157_gene1448	5.631e-32	139.0	COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4I27S@91061|Bacilli,4GX44@90964|Staphylococcaceae	91061|Bacilli	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,LysM
SRR25158343_k127_1831314_5	1150474.JQJI01000001_gene1858	1.972e-99	338.0	COG0536@1|root,COG0536@2|Bacteria,2GCFB@200918|Thermotogae	200918|Thermotogae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158343_k127_1831314_17	237368.SCABRO_03007	2.33e-11	76.0	2A1MP@1|root,30PVX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1831314_3	1122201.AUAZ01000005_gene594	6.892e-113	380.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2925 Exonuclease I	sbcB	GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
SRR25158343_k127_1831314_0	264732.Moth_0255	0.0	1187.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158343_k127_1831314_10	179408.Osc7112_4384	1.452e-50	189.0	COG0586@1|root,COG0586@2|Bacteria,1G4C6@1117|Cyanobacteria,1HHG1@1150|Oscillatoriales	1117|Cyanobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158343_k127_1831314_15	383372.Rcas_1070	3.153e-18	93.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi,375RP@32061|Chloroflexia	32061|Chloroflexia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158343_k127_1831314_11	1122611.KB904011_gene6846	2.75e-45	165.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria,4EHHY@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1906497_8	523841.HFX_1343	5.694e-21	101.0	arCOG01782@1|root,arCOG01782@2157|Archaea,2XT72@28890|Euryarchaeota,23UM6@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158343_k127_1906497_11	102129.Lepto7375DRAFT_2809	2.77e-12	72.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158343_k127_1906497_2	1128421.JAGA01000003_gene3053	1.568e-65	243.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
SRR25158343_k127_1906497_3	985867.AEWF01000002_gene1418	5.874e-52	190.0	COG1051@1|root,COG1051@2|Bacteria,1Q922@1224|Proteobacteria,2URFC@28211|Alphaproteobacteria,47F9R@766|Rickettsiales	766|Rickettsiales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1906497_5	1122182.KB903813_gene2582	5.085e-34	144.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	Beta_helix,CHAP,FG-GAP,NLPC_P60,Transglycosylas,VCBS
SRR25158343_k127_1906497_7	638303.Thal_0818	1.491e-22	103.0	COG0615@1|root,COG0615@2|Bacteria,2G3YJ@200783|Aquificae	200783|Aquificae	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
SRR25158343_k127_1906497_10	929562.Emtol_1048	3.138e-20	96.0	COG3059@1|root,COG3059@2|Bacteria,4P9H9@976|Bacteroidetes,47RAZ@768503|Cytophagia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1906497_9	1198449.ACAM_0725	1.174e-20	100.0	COG0127@1|root,arCOG04184@2157|Archaea,2XQHP@28889|Crenarchaeota	28889|Crenarchaeota	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	ntpA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158343_k127_1906497_6	1291743.LOSG293_050060	4.994e-33	139.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae	91061|Bacilli	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158343_k127_1906497_1	401526.TcarDRAFT_0928	1.552e-175	569.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4H2PQ@909932|Negativicutes	909932|Negativicutes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158343_k127_1906497_4	525904.Tter_1610	8.435e-39	163.0	COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria	2|Bacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158343_k127_1906497_0	525904.Tter_0948	1.128e-207	661.0	COG0481@1|root,COG0481@2|Bacteria,2NNXG@2323|unclassified Bacteria	2|Bacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158343_k127_1906497_12	1123503.KB908060_gene145	2.548e-08	62.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,2KGBR@204458|Caulobacterales	204458|Caulobacterales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158343_k127_1951659_0	748727.CLJU_c01660	5.077e-29	128.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,36W69@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158343_k127_1951659_1	1150469.RSPPHO_02781	3.043e-06	49.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_195285_1	1385517.N800_15150	1.97e-126	410.0	COG1680@1|root,COG1680@2|Bacteria,1QJH7@1224|Proteobacteria,1S0KP@1236|Gammaproteobacteria,1X3UV@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_195285_0	1120953.AUBH01000010_gene111	7.406e-147	477.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,466QD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158343_k127_195285_2	313590.MED134_03534	1.291e-65	235.0	COG2207@1|root,COG2207@2|Bacteria,4NIRD@976|Bacteroidetes,1I0T7@117743|Flavobacteriia	976|Bacteroidetes	K	dna-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158343_k127_1964201_24	1122228.AQXR01000008_gene709	5.499e-08	62.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158343_k127_1964201_1	526227.Mesil_2174	1.003e-125	417.0	COG0423@1|root,COG0423@2|Bacteria,1WIB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158343_k127_1964201_5	1380347.JNII01000006_gene1386	2.047e-75	262.0	COG3064@1|root,COG3064@2|Bacteria,2IPMP@201174|Actinobacteria,4EWGV@85013|Frankiales	201174|Actinobacteria	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1964201_25	502558.EGYY_14670	6.841e-08	62.0	COG1432@1|root,COG1432@2|Bacteria,2HVW0@201174|Actinobacteria,4CXKZ@84998|Coriobacteriia	84998|Coriobacteriia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158343_k127_1964201_14	1194165.CAJF01000026_gene3333	3.916e-43	161.0	2DS51@1|root,33EJB@2|Bacteria,2IM77@201174|Actinobacteria,4FPD7@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158343_k127_1964201_21	330214.NIDE2428	1.592e-17	88.0	COG3431@1|root,COG3431@2|Bacteria,3J1A3@40117|Nitrospirae	40117|Nitrospirae	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
SRR25158343_k127_1964201_2	1121877.JQKF01000045_gene1204	9.197e-118	397.0	COG0210@1|root,COG0507@1|root,COG0210@2|Bacteria,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD2	-	3.6.4.12	ko:K03657,ko:K15255	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032,ko03400	-	-	-	AAA_11,AAA_12,AAA_19,HTH_40,PIF1,PLDc_2,UvrD-helicase,UvrD_C,UvrD_C_2
SRR25158343_k127_1964201_26	1123322.KB904652_gene526	2.056e-06	54.0	2E6DR@1|root,3311A@2|Bacteria,2IKTW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1964201_17	747365.Thena_0582	3.927e-35	142.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,25JY3@186801|Clostridia,42IIJ@68295|Thermoanaerobacterales	186801|Clostridia	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158343_k127_1964201_20	523850.TON_1624	8.4e-20	97.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,243AW@183968|Thermococci	183968|Thermococci	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
SRR25158343_k127_1964201_10	289376.THEYE_A1186	3.211e-59	212.0	COG2003@1|root,COG2003@2|Bacteria,3J12V@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158343_k127_1964201_23	1203568.HMPREF1484_00048	2.927e-13	74.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4FCP1@85020|Dermabacteraceae	201174|Actinobacteria	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158343_k127_1964201_8	395961.Cyan7425_3751	2.557e-65	233.0	COG0275@1|root,COG0275@2|Bacteria,1G0AR@1117|Cyanobacteria,3KH7K@43988|Cyanothece	1117|Cyanobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158343_k127_1964201_6	525904.Tter_1614	1.784e-71	263.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
SRR25158343_k127_1964201_7	1382356.JQMP01000004_gene471	3.551e-68	244.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158343_k127_1964201_9	1274524.BSONL12_11431	1.182e-63	234.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBY5@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158343_k127_1964201_13	1410650.JHWL01000003_gene2914	8.395e-44	174.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,4BY9U@830|Butyrivibrio	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158343_k127_1964201_27	411460.RUMTOR_00791	2.557e-06	59.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,24XIM@186801|Clostridia,3Y0YK@572511|Blautia	186801|Clostridia	K	Sigma-70 factor, region 1.2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_1964201_0	926549.KI421517_gene3766	1.733e-259	821.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158343_k127_1964201_11	667014.Thein_1585	1.283e-56	209.0	COG0758@1|root,COG0758@2|Bacteria,2GHI2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158343_k127_1964201_16	1188256.BASI01000005_gene1957	1.472e-37	149.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,3FD21@34008|Rhodovulum	28211|Alphaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158343_k127_1964201_3	324602.Caur_3106	2.367e-97	334.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,375A1@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158343_k127_1964201_15	1396141.BATP01000059_gene2585	4.205e-43	166.0	COG1187@1|root,COG1187@2|Bacteria,46SWQ@74201|Verrucomicrobia,2IUBZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_1964201_22	1122212.AULO01000007_gene2594	1.805e-17	96.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,1XPFN@135619|Oceanospirillales	135619|Oceanospirillales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158343_k127_1964201_12	941639.BCO26_0690	2.378e-45	185.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus	91061|Bacilli	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRR25158343_k127_1964201_4	455632.SGR_219	5.069e-94	317.0	COG0702@1|root,COG0702@2|Bacteria,2HBFK@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158343_k127_1964201_18	1183438.GKIL_4112	1.382e-22	100.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158343_k127_1964201_19	331678.Cphamn1_0140	7.532e-20	93.0	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	GO:0000166,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0003842,GO:0004657,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006355,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009889,GO:0009890,GO:0009892,GO:0009898,GO:0009987,GO:0010133,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043565,GO:0043648,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0048519,GO:0048523,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0098552,GO:0098562,GO:0140110,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iPC815.YPO1851,iSbBS512_1146.SbBS512_E2304	Aldedh,Pro_dh,Pro_dh-DNA_bdg,RHH_1
SRR25158343_k127_1973394_5	7425.NV12514-PA	5.002e-06	50.0	COG0563@1|root,KOG3079@2759|Eukaryota,38HJ3@33154|Opisthokonta,3BD3B@33208|Metazoa,3CXR5@33213|Bilateria,41YRI@6656|Arthropoda,3SM4H@50557|Insecta,46H9X@7399|Hymenoptera	33208|Metazoa	F	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors	CMPK1	GO:0000003,GO:0003674,GO:0003824,GO:0004127,GO:0004550,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006165,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006225,GO:0006227,GO:0006240,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009185,GO:0009186,GO:0009188,GO:0009189,GO:0009193,GO:0009194,GO:0009196,GO:0009197,GO:0009218,GO:0009219,GO:0009220,GO:0009221,GO:0009259,GO:0009260,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0018963,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0019752,GO:0019856,GO:0022414,GO:0022602,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0036430,GO:0042455,GO:0042537,GO:0042698,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046048,GO:0046049,GO:0046062,GO:0046077,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046385,GO:0046390,GO:0046483,GO:0046704,GO:0046705,GO:0046939,GO:0046940,GO:0048511,GO:0048609,GO:0050145,GO:0055086,GO:0070013,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.14	ko:K13800	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00052	R00158,R00512,R01665,R11891,R11892	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	ADK
SRR25158343_k127_1973394_3	1354314.CHV_a0211	2.165e-65	231.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,47KDT@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158343_k127_1973394_1	1382306.JNIM01000001_gene41	4.441e-82	287.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158343_k127_1973394_0	203119.Cthe_0445	1.357e-121	405.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158343_k127_1973394_4	1345697.M493_14125	3.157e-49	180.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,1WG2W@129337|Geobacillus	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158343_k127_1973394_2	1236902.ANAS01000023_gene3339	1.215e-80	276.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4EGWK@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158343_k127_1996164_12	1224318.DT73_23675	5.767e-08	57.0	COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair	tatD	GO:0000175,GO:0000302,GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009056,GO:0009057,GO:0009636,GO:0009987,GO:0010035,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046700,GO:0046872,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901700	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158343_k127_1996164_0	1110502.TMO_1679	1.396e-120	403.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,2JPGA@204441|Rhodospirillales	204441|Rhodospirillales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158343_k127_1996164_4	754035.Mesau_03183	9.45e-53	192.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,43KUC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1996164_16	1109445.AGSX01000042_gene426	0.0006418	51.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1T25X@1236|Gammaproteobacteria,1YZWP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,Response_reg
SRR25158343_k127_1996164_9	1094980.Mpsy_1538	2.513e-16	93.0	COG2304@1|root,COG4934@1|root,arCOG02902@2157|Archaea,arCOG03665@2157|Archaea	2157|Archaea	O	tripeptidyl-peptidase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,Peptidase_S8,Pro-kuma_activ,VWA,VWA_2
SRR25158343_k127_1996164_13	436229.JOEH01000034_gene3533	1.771e-06	60.0	COG1361@1|root,COG1361@2|Bacteria,2HZGC@201174|Actinobacteria,2NF9J@228398|Streptacidiphilus	201174|Actinobacteria	M	Bacterial protein of unknown function (DUF916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF916
SRR25158343_k127_1996164_1	1123354.AUDR01000003_gene1561	7e-116	383.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,1KS3I@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_1996164_7	517418.Ctha_1785	1.07e-45	176.0	COG0077@1|root,COG0077@2|Bacteria,1FDK0@1090|Chlorobi	1090|Chlorobi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158343_k127_1996164_11	673860.AciM339_0691	1.773e-08	64.0	COG0317@1|root,arCOG06870@2157|Archaea	2157|Archaea	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
SRR25158343_k127_1996164_10	882083.SacmaDRAFT_4368	3.682e-13	75.0	COG1011@1|root,COG1011@2|Bacteria,2ISUR@201174|Actinobacteria,4E5JP@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR25158343_k127_1996164_5	1157637.KB892109_gene4419	1.624e-49	183.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1996164_6	1121019.AUMN01000004_gene1324	2.644e-48	178.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria,1WBMA@1268|Micrococcaceae	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158343_k127_1996164_14	1140002.I570_01122	2.103e-05	55.0	COG1940@1|root,COG1940@2|Bacteria,1UWY8@1239|Firmicutes,4I34Z@91061|Bacilli,4B228@81852|Enterococcaceae	91061|Bacilli	GK	Glucokinase	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158343_k127_1996164_15	219305.MCAG_05543	0.0003092	49.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,TIR_2,Trypsin_2,WD40
SRR25158343_k127_1996164_3	1123252.ATZF01000017_gene1718	6.772e-73	253.0	COG2267@1|root,COG2267@2|Bacteria,1UHSX@1239|Firmicutes,4IS8N@91061|Bacilli	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1996164_2	926550.CLDAP_30600	1.378e-73	255.0	COG1478@1|root,COG1478@2|Bacteria	2|Bacteria	S	coenzyme F420-1:gamma-L-glutamate ligase activity	CP_1112	-	6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34	ko:K12234,ko:K22099	ko00680,ko00790,ko01120,map00680,map00790,map01120	M00378,M00840	R00942,R02237,R04241,R09399,R09400	RC00064,RC00090,RC00141,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158343_k127_2000161_21	649831.L083_6735	2.981e-25	108.0	COG1694@1|root,COG1694@2|Bacteria,2INKJ@201174|Actinobacteria,4DEQB@85008|Micromonosporales	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158343_k127_2000161_11	706587.Desti_4437	3.583e-71	250.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MQVX@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM HhH-GPD superfamily base excision DNA repair protein	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRR25158343_k127_2000161_6	1122182.KB903839_gene996	9.543e-99	337.0	COG0017@1|root,COG0017@2|Bacteria,2I2KQ@201174|Actinobacteria,4D8VG@85008|Micromonosporales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158343_k127_2000161_33	987059.RBXJA2T_02931	1.12e-06	60.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,1KK97@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
SRR25158343_k127_2000161_19	1121890.AUDO01000004_gene2094	3.513e-31	131.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1I1EZ@117743|Flavobacteriia,2NWHS@237|Flavobacterium	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158343_k127_2000161_31	469381.Dpep_0051	3.504e-11	70.0	COG2856@1|root,COG2856@2|Bacteria,3TBV1@508458|Synergistetes	508458|Synergistetes	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158343_k127_2000161_13	880071.Fleli_2809	1.401e-55	203.0	COG0368@1|root,COG0368@2|Bacteria,4NHNT@976|Bacteroidetes,47MF0@768503|Cytophagia	976|Bacteroidetes	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158343_k127_2000161_18	686340.Metal_3923	8.819e-34	138.0	COG0406@1|root,COG0406@2|Bacteria,1N14H@1224|Proteobacteria,1SBX7@1236|Gammaproteobacteria,1XGZW@135618|Methylococcales	135618|Methylococcales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158343_k127_2000161_30	1340493.JNIF01000003_gene1795	1.924e-11	70.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria	57723|Acidobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158343_k127_2000161_37	1184607.AUCHE_09_00650	0.0001663	49.0	COG2246@1|root,COG2246@2|Bacteria,2GT0Q@201174|Actinobacteria	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158343_k127_2000161_29	1244528.CFT03427_0342	7.628e-13	77.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2YNHV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
SRR25158343_k127_2000161_34	928724.SacglDRAFT_01805	1.536e-06	58.0	COG0500@1|root,COG2226@2|Bacteria,2HFM8@201174|Actinobacteria,4DYRC@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	crtT	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158343_k127_2000161_14	926569.ANT_19980	7.495e-52	202.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G67F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158343_k127_2000161_10	485913.Krac_7830	1.59e-75	267.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2000161_17	1123304.AQYA01000035_gene1020	1.005e-36	147.0	COG4185@1|root,COG4185@2|Bacteria,1V28J@1239|Firmicutes,4HGK7@91061|Bacilli	91061|Bacilli	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
SRR25158343_k127_2000161_23	1121342.AUCO01000011_gene2941	4.762e-25	115.0	COG0560@1|root,COG0560@2|Bacteria,1V4PY@1239|Firmicutes,25CGU@186801|Clostridia,36WVR@31979|Clostridiaceae	186801|Clostridia	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158343_k127_2000161_38	519989.ECTPHS_11989	0.0001761	52.0	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1RY1Q@1236|Gammaproteobacteria,1WX7C@135613|Chromatiales	135613|Chromatiales	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158343_k127_2000161_16	56780.SYN_01031	2.4e-38	157.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2MQDR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Nucleotidyl transferase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158343_k127_2000161_4	479434.Sthe_1355	9.18e-127	419.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158343_k127_2000161_0	479435.Kfla_3744	3.764e-153	491.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4DPM2@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_2000161_32	1248760.ANFZ01000013_gene1868	1.112e-10	64.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,2UJBM@28211|Alphaproteobacteria,2K7JS@204457|Sphingomonadales	204457|Sphingomonadales	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158343_k127_2000161_35	261292.Nit79A3_0970	7.344e-06	53.0	COG5573@1|root,COG5573@2|Bacteria,1N3BU@1224|Proteobacteria,2VX6S@28216|Betaproteobacteria,373B1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158343_k127_2000161_9	222534.KB893670_gene3838	1.091e-80	272.0	COG1898@1|root,COG1898@2|Bacteria,2I5HZ@201174|Actinobacteria	201174|Actinobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158343_k127_2000161_8	1122609.AUGT01000009_gene3168	1.158e-91	309.0	COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4DN84@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
SRR25158343_k127_2000161_3	298655.KI912266_gene1381	1.011e-138	445.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4ETV6@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0334	NTP_transferase
SRR25158343_k127_2000161_28	1296416.JACB01000036_gene2828	3.396e-13	74.0	2ACPE@1|root,312A1@2|Bacteria,4PH64@976|Bacteroidetes,1IMCS@117743|Flavobacteriia,2YJZB@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2000161_1	1296416.JACB01000036_gene2829	2.201e-148	488.0	COG2303@1|root,COG2303@2|Bacteria,4PH1X@976|Bacteroidetes,1IMAH@117743|Flavobacteriia,2YJ6R@290174|Aquimarina	976|Bacteroidetes	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2000161_27	317655.Sala_2220	2.975e-13	80.0	COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,2K0TF@204457|Sphingomonadales	204457|Sphingomonadales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158343_k127_2000161_12	1687.BCOR_0220	2.423e-62	222.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	kfoC	-	-	-	-	-	-	-	-	-	-	-	GlcNAc,Glyco_transf_7C,Glycos_transf_2
SRR25158343_k127_2000161_20	1220534.B655_1615	1.254e-27	117.0	COG2246@1|root,arCOG02228@2157|Archaea,2Y20I@28890|Euryarchaeota,23PR3@183925|Methanobacteria	183925|Methanobacteria	S	PFAM GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158343_k127_2000161_24	77635.BISU_1038	8.224e-19	93.0	COG0671@1|root,COG0671@2|Bacteria,2HZQV@201174|Actinobacteria,4D1AP@85004|Bifidobacteriales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158343_k127_2000161_5	272568.GDI3373	3.218e-122	421.0	COG4485@1|root,COG4485@2|Bacteria,1QGV0@1224|Proteobacteria	1224|Proteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2000161_25	590998.Celf_2499	2.486e-17	96.0	COG3858@1|root,COG5479@1|root,COG3858@2|Bacteria,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria	201174|Actinobacteria	M	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LGFP
SRR25158343_k127_2000161_26	36630.CADNFIAP00000974	1.769e-16	93.0	2EGJ7@1|root,2SMGR@2759|Eukaryota,39WHG@33154|Opisthokonta,3NZGG@4751|Fungi,3QXT1@4890|Ascomycota,20MYK@147545|Eurotiomycetes,3S8HM@5042|Eurotiales	4751|Fungi	S	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HET,VCBS
SRR25158343_k127_2000161_2	1536775.H70737_27870	5.946e-148	489.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,4HE8D@91061|Bacilli,26UJK@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
SRR25158343_k127_2000161_15	1121924.ATWH01000013_gene564	1.677e-45	177.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_2,TPR_8
SRR25158343_k127_2000161_7	1346.DQ08_05710	1.734e-92	319.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli	91061|Bacilli	P	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system	rgpD	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158343_k127_2000161_36	561180.BIFGAL_03969	2.387e-05	48.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CZ73@85004|Bifidobacteriales	201174|Actinobacteria	U	Transport permease protein	tagG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158343_k127_2000325_1	469383.Cwoe_5676	1.179e-129	418.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158343_k127_2000325_8	1121035.AUCH01000013_gene3142	6.648e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158343_k127_2000325_12	1120936.KB907209_gene1785	3.62e-09	66.0	arCOG06881@1|root,32GSN@2|Bacteria,2H4NV@201174|Actinobacteria,4ENR2@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2000325_3	2074.JNYD01000066_gene6458	8.917e-53	200.0	COG1597@1|root,COG1597@2|Bacteria,2HQQU@201174|Actinobacteria,4E9MR@85010|Pseudonocardiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158343_k127_2000325_9	1317124.DW2_04740	9.187e-14	82.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,2TST9@28211|Alphaproteobacteria,2XMJC@285107|Thioclava	28211|Alphaproteobacteria	G	Carbohydrate kinase	frk	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158343_k127_2000325_4	717774.Marme_4210	9.614e-48	181.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,1RS6X@1236|Gammaproteobacteria,1XITG@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
SRR25158343_k127_2000325_5	1150398.JIBJ01000008_gene628	1.144e-28	125.0	COG2367@1|root,COG2367@2|Bacteria,2HTQA@201174|Actinobacteria,1WC25@1268|Micrococcaceae	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRR25158343_k127_2000325_6	864051.BurJ1DRAFT_0558	1.58e-27	114.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158343_k127_2000325_10	525260.HMPREF0276_0714	9.618e-11	74.0	COG1749@1|root,COG2374@1|root,COG1749@2|Bacteria,COG2374@2|Bacteria,2HVE1@201174|Actinobacteria,22K38@1653|Corynebacteriaceae	201174|Actinobacteria	N	extracellular nuclease	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Collagen,Exo_endo_phos,LTD,Rib
SRR25158343_k127_2000325_11	983548.Krodi_0608	1.098e-10	74.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia,37ER8@326319|Dokdonia	976|Bacteroidetes	S	Domain of unknown function (DUF4131)	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
SRR25158343_k127_2000325_2	2074.JNYD01000006_gene1794	1.398e-75	261.0	COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4E5TG@85010|Pseudonocardiales	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,Excalibur
SRR25158343_k127_2000325_0	390989.JOEG01000024_gene6107	1.061e-169	554.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria,4DBRW@85008|Micromonosporales	201174|Actinobacteria	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158343_k127_2000325_13	196162.Noca_0715	2.236e-08	61.0	COG1051@1|root,COG1051@2|Bacteria,2GPP2@201174|Actinobacteria,4DQE2@85009|Propionibacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_2000325_7	1278308.KB907083_gene362	2.773e-19	102.0	COG1807@1|root,COG1807@2|Bacteria,2H5NR@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2006902_2	1121335.Clst_0952	8.271e-15	80.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24U24@186801|Clostridia,3WJ3V@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158343_k127_2006902_1	380358.XALC_0355	5.598e-18	92.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1X691@135614|Xanthomonadales	135614|Xanthomonadales	S	competence protein	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158343_k127_2006902_3	1168059.KB899087_gene1061	3.156e-10	66.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_2006902_0	1173263.Syn7502_03353	1.067e-22	106.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_2075091_0	1121877.JQKF01000002_gene1700	1.762e-281	879.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158343_k127_2097848_0	1499967.BAYZ01000074_gene2127	2.037e-36	147.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158343_k127_2097848_1	1237149.C900_00045	2.014e-07	61.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes,47RG0@768503|Cytophagia	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158343_k127_2100700_5	1122182.KB903817_gene1802	6.126e-93	320.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4DDU5@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158343_k127_2100700_9	985665.HPL003_19530	1.393e-76	266.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,26RT6@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
SRR25158343_k127_2100700_33	864565.HMPREF0379_1804	2.116e-14	78.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,24JQE@186801|Clostridia,25RK9@186804|Peptostreptococcaceae	186801|Clostridia	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158343_k127_2100700_41	1033740.CAEW01000025_gene690	1.117e-06	52.0	COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HIE1@91061|Bacilli,26FS5@186818|Planococcaceae	91061|Bacilli	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158343_k127_2100700_47	1333523.L593_09020	0.0001682	46.0	COG0537@1|root,arCOG00419@2157|Archaea,2XXWC@28890|Euryarchaeota,23V8Q@183963|Halobacteria	183963|Halobacteria	F	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit2	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158343_k127_2100700_37	926561.KB900618_gene217	1.975e-10	68.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia	186801|Clostridia	P	Chromate	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158343_k127_2100700_35	246199.CUS_5435	2.435e-12	74.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,3WJYR@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	chrA2	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158343_k127_2100700_4	1437425.CSEC_2435	1.673e-96	327.0	COG1622@1|root,COG1622@2|Bacteria,2JFR4@204428|Chlamydiae	204428|Chlamydiae	C	COX Aromatic Rich Motif	cyoA	-	1.10.3.10	ko:K02297	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX2,COX_ARM
SRR25158343_k127_2100700_0	1444712.BN1013_00113	4.863e-299	929.0	COG0843@1|root,COG0843@2|Bacteria,2JFT7@204428|Chlamydiae	204428|Chlamydiae	C	Cytochrome C and Quinol oxidase polypeptide I	cyoB	-	1.10.3.10	ko:K02298	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX1
SRR25158343_k127_2100700_11	1076550.LH22_17590	1.078e-68	239.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,3VY2G@53335|Pantoea	1236|Gammaproteobacteria	C	cytochrome o ubiquinol oxidase, subunit III	cyoC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0019646,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070069,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902494,GO:1902600	-	ko:K02299	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	iPC815.YPO3166	COX3
SRR25158343_k127_2100700_27	1444711.CCJF01000005_gene1099	8.984e-21	100.0	COG3125@1|root,COG3125@2|Bacteria,2JGFM@204428|Chlamydiae	204428|Chlamydiae	C	Prokaryotic Cytochrome C oxidase subunit IV	cyoD	-	-	ko:K02300	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX4_pro
SRR25158343_k127_2100700_7	1444711.CCJF01000005_gene1098	1.924e-89	303.0	COG0109@1|root,COG0109@2|Bacteria,2JFWP@204428|Chlamydiae	204428|Chlamydiae	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158343_k127_2100700_24	525904.Tter_1681	1.265e-23	115.0	COG2843@1|root,COG3103@1|root,COG2843@2|Bacteria,COG4991@2|Bacteria,2NPJI@2323|unclassified Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	2.7.11.1	ko:K07282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PGA_cap,SH3_3,SH3_4
SRR25158343_k127_2100700_8	489825.LYNGBM3L_30690	4.939e-80	282.0	COG0285@1|root,COG0285@2|Bacteria	2|Bacteria	H	dihydrofolate synthase activity	capB	-	6.3.2.12,6.3.2.17	ko:K01932,ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_2100700_40	36809.MAB_0162c	1.09e-06	58.0	COG4322@1|root,COG4322@2|Bacteria,2IDUB@201174|Actinobacteria,23EZD@1762|Mycobacteriaceae	201174|Actinobacteria	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
SRR25158343_k127_2100700_39	329726.AM1_6107	2.003e-07	59.0	COG0702@1|root,COG0702@2|Bacteria,1G3PB@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158343_k127_2100700_6	566461.SSFG_01032	1.383e-90	325.0	COG0791@1|root,COG3291@1|root,COG0791@2|Bacteria,COG3291@2|Bacteria,2GT7N@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall-associated hydrolases (Invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158343_k127_2100700_28	996637.SGM_1197	4.644e-20	96.0	COG3103@1|root,COG4991@2|Bacteria,2INEH@201174|Actinobacteria	201174|Actinobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158343_k127_2100700_38	1220534.B655_1810	1.748e-07	61.0	COG0560@1|root,COG1340@1|root,arCOG01158@2157|Archaea,arCOG01159@2157|Archaea,2XT0C@28890|Euryarchaeota,23NM8@183925|Methanobacteria	183925|Methanobacteria	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
SRR25158343_k127_2100700_44	1280001.BAOA01000039_gene2493	1.017e-05	57.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XTHJ@135623|Vibrionales	135623|Vibrionales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008997,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
SRR25158343_k127_2100700_23	1451189.CFAL_00755	5.325e-24	115.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,22JP8@1653|Corynebacteriaceae	201174|Actinobacteria	K	function transcriptional attenuator common domain protein	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158343_k127_2100700_48	665950.HMPREF1025_02255	0.000321	52.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,27KN2@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158343_k127_2100700_25	696281.Desru_3851	1.933e-21	98.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,262DN@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158343_k127_2100700_20	1121912.AUHD01000002_gene3301	9.41e-45	169.0	COG0431@1|root,COG0431@2|Bacteria,4NN31@976|Bacteroidetes,1IB8A@117743|Flavobacteriia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158343_k127_2100700_13	483219.LILAB_25725	2.116e-64	227.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2YV3E@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
SRR25158343_k127_2100700_46	313612.L8106_13935	0.0001065	51.0	COG0748@1|root,COG0748@2|Bacteria,1G7EG@1117|Cyanobacteria,1HC06@1150|Oscillatoriales	1117|Cyanobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158343_k127_2100700_31	717231.Flexsi_1964	3.59e-15	81.0	COG1837@1|root,COG1837@2|Bacteria,2GFZI@200930|Deferribacteres	200930|Deferribacteres	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158343_k127_2100700_34	1188236.MARG_1140	1.793e-12	72.0	COG0228@1|root,COG0228@2|Bacteria,3WTVG@544448|Tenericutes	544448|Tenericutes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158343_k127_2100700_19	1158608.I583_02628	7.872e-49	184.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,4B0CI@81852|Enterococcaceae	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158343_k127_2100700_32	1329516.JPST01000035_gene3173	5.639e-15	81.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,27C00@186824|Thermoactinomycetaceae	91061|Bacilli	F	NUDIX domain	apfA	-	3.6.1.61	ko:K18445	ko00230,map00230	-	R00184	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158343_k127_2100700_22	1382356.JQMP01000003_gene1311	1.246e-25	111.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi,27YFI@189775|Thermomicrobia	189775|Thermomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158343_k127_2100700_1	986075.CathTA2_2210	5.862e-265	839.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158343_k127_2100700_10	1121020.JIAG01000005_gene2322	7.453e-76	261.0	COG2872@1|root,COG2872@2|Bacteria,2HTR2@201174|Actinobacteria,1WC4E@1268|Micrococcaceae	201174|Actinobacteria	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_SAD
SRR25158343_k127_2100700_18	862967.SIR_0630	2.857e-49	185.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,42E5W@671232|Streptococcus anginosus group	91061|Bacilli	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158343_k127_2100700_16	502558.EGYY_30010	6.774e-58	213.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4CU9A@84998|Coriobacteriia	84998|Coriobacteriia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158343_k127_2100700_12	1278073.MYSTI_04345	1.244e-67	250.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_2100700_29	208444.JNYY01000009_gene3352	1.06e-19	94.0	COG1396@1|root,COG2944@1|root,COG1396@2|Bacteria,COG2944@2|Bacteria,2IBMZ@201174|Actinobacteria	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2100700_26	114615.BRADO0690	6.963e-21	103.0	COG0189@1|root,COG0189@2|Bacteria,1PBT7@1224|Proteobacteria,2TVR7@28211|Alphaproteobacteria,3JTWH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_2100700_17	1196324.A374_05301	2.173e-50	191.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli	91061|Bacilli	P	COG0598 Mg2 and Co2 transporters	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158343_k127_2100700_30	264731.PRU_2628	1.844e-15	83.0	COG1051@1|root,COG1998@1|root,COG1051@2|Bacteria,COG1998@2|Bacteria,4NP2X@976|Bacteroidetes,2FMSZ@200643|Bacteroidia	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,zf-NADH-PPase
SRR25158343_k127_2100700_21	485913.Krac_5282	1.553e-36	145.0	COG0127@1|root,COG0127@2|Bacteria	2|Bacteria	F	nucleoside triphosphate catabolic process	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Ham1p_like
SRR25158343_k127_2100700_2	118163.Ple7327_3341	2.286e-162	534.0	COG0272@1|root,COG0272@2|Bacteria,1G12K@1117|Cyanobacteria,3VIN6@52604|Pleurocapsales	1117|Cyanobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158343_k127_2100700_3	1120959.ATXF01000007_gene2411	1.807e-104	347.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FMKM@85023|Microbacteriaceae	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158343_k127_2100700_15	1416759.AYMR01000020_gene26	5.508e-58	207.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4FK45@85023|Microbacteriaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158343_k127_2100700_42	391612.CY0110_00790	1.949e-06	61.0	COG0557@1|root,COG0557@2|Bacteria,1G3WK@1117|Cyanobacteria,3KHJT@43988|Cyanothece	1117|Cyanobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,dsrm
SRR25158343_k127_2100700_14	1150399.AQYK01000002_gene2138	1.582e-63	233.0	COG1686@1|root,COG1686@2|Bacteria,2GM2X@201174|Actinobacteria,4FMB7@85023|Microbacteriaceae	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR25158343_k127_21114_1	479433.Caci_4080	5.18e-119	406.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
SRR25158343_k127_21114_13	479431.Namu_2532	2.341e-06	61.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,NLPC_P60,PG_binding_1,PhageMin_Tail
SRR25158343_k127_21114_14	1288.SXYLSMQ121_0125	0.00062	52.0	COG1388@1|root,COG1388@2|Bacteria,1V7FX@1239|Firmicutes,4HJS7@91061|Bacilli,4GXPS@90964|Staphylococcaceae	91061|Bacilli	M	Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells	sceD	-	-	-	-	-	-	-	-	-	-	-	Transglycosylas
SRR25158343_k127_21114_6	887929.HMP0721_1865	1.459e-53	202.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,25V7R@186806|Eubacteriaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158343_k127_21114_5	765420.OSCT_2682	7.702e-72	256.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,374SP@32061|Chloroflexia	32061|Chloroflexia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158343_k127_21114_2	1120973.AQXL01000114_gene719	3.184e-116	389.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,277VV@186823|Alicyclobacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158343_k127_21114_11	552398.HMPREF0866_02545	5.31e-11	63.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3WM8B@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158343_k127_21114_12	383372.Rcas_1424	1.555e-07	59.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,375ZH@32061|Chloroflexia	32061|Chloroflexia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158343_k127_21114_8	1408422.JHYF01000006_gene1019	1.205e-18	97.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,36FE7@31979|Clostridiaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158343_k127_21114_9	1122602.ATXP01000005_gene2073	1.736e-15	82.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,1W97Y@1268|Micrococcaceae	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158343_k127_21114_7	1499689.CCNN01000007_gene979	1.942e-38	159.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia,36E4C@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_21114_15	1197906.CAJQ02000010_gene3441	0.0008626	52.0	COG3307@1|root,COG3307@2|Bacteria,1MWJM@1224|Proteobacteria,2TRG6@28211|Alphaproteobacteria,3JUWK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	-O-antigen	MA20_36890	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158343_k127_21114_4	1121430.JMLG01000005_gene705	6.941e-86	291.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158343_k127_21114_0	760568.Desku_1534	0.0	1066.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SRR25158343_k127_21114_3	688269.Theth_0190	8.66e-91	312.0	COG0026@1|root,COG0026@2|Bacteria	2|Bacteria	F	5-(carboxyamino)imidazole ribonucleotide synthase activity	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	ATP-grasp
SRR25158343_k127_2138994_0	1347086.CCBA010000023_gene2067	8.84e-10	66.0	COG1051@1|root,COG1051@2|Bacteria,1V6ZQ@1239|Firmicutes,4HIQM@91061|Bacilli,1ZIC1@1386|Bacillus	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_2138994_1	1038859.AXAU01000002_gene750	0.0002641	51.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,AKAP7_NLS
SRR25158343_k127_2181762_8	313612.L8106_02282	1.176e-17	96.0	COG1520@1|root,COG2931@1|root,COG4886@1|root,COG5276@1|root,COG5373@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4886@2|Bacteria,COG5276@2|Bacteria,COG5373@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,Peptidase_M10_C
SRR25158343_k127_2181762_12	1212548.B381_17674	0.0003415	49.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1Z3FG@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NU	COG4969 Tfp pilus assembly protein, major pilin PilA	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
SRR25158343_k127_2181762_5	1499680.CCFE01000018_gene1436	5.362e-32	139.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,1ZD1H@1386|Bacillus	91061|Bacilli	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158343_k127_2181762_1	1304865.JAGF01000001_gene3210	1.583e-109	374.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158343_k127_2181762_7	557436.Lreu_0058	1.698e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HG2E@91061|Bacilli,3F53G@33958|Lactobacillaceae	91061|Bacilli	K	response regulator	dltr	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_2181762_4	1133850.SHJG_7760	1.206e-41	157.0	2DMJC@1|root,32RYJ@2|Bacteria,2IHZV@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4186)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186
SRR25158343_k127_2181762_9	1463825.JNXC01000003_gene3807	3.338e-14	78.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4E1ZE@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_2181762_6	1077144.AGFF01000007_gene1686	1.072e-29	124.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_2181762_3	1121272.KB903290_gene4659	7.44e-43	164.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4D8QU@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_2181762_10	1297581.H919_08245	4.766e-12	76.0	COG1277@1|root,COG1277@2|Bacteria,1V1P1@1239|Firmicutes,4HCZ3@91061|Bacilli,21W53@150247|Anoxybacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158343_k127_2181762_0	1380394.JADL01000009_gene3334	7.312e-117	386.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
SRR25158343_k127_2181762_11	1032480.MLP_13640	3.987e-05	55.0	COG3173@1|root,COG3173@2|Bacteria,2GMHD@201174|Actinobacteria,4DRQU@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158343_k127_2181762_2	946077.W5A_13535	1.766e-95	325.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_19,HTH_3
SRR25158343_k127_2196063_4	1115515.EV102420_02_02960	0.0003272	55.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1RQSJ@1236|Gammaproteobacteria,3XM4R@561|Escherichia	1236|Gammaproteobacteria	O	Metalloprotease that cleaves substrates preferentially between Phe-Phe residues. Plays a role in response to some stress conditions. Seems to regulate the expression of speB	yggG	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0006971,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009266,GO:0009279,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0034605,GO:0034644,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0070011,GO:0071214,GO:0071470,GO:0071476,GO:0071478,GO:0071482,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564	-	ko:K07387	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158343_k127_2196063_2	313612.L8106_06854	4.305e-35	138.0	COG0080@1|root,COG0080@2|Bacteria,1G4ZJ@1117|Cyanobacteria,1HAME@1150|Oscillatoriales	1117|Cyanobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158343_k127_2196063_0	644966.Tmar_2308	3.095e-65	227.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WCHU@538999|Clostridiales incertae sedis	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158343_k127_2196063_3	933115.GPDM_13231	2.036e-18	99.0	COG1215@1|root,COG1215@2|Bacteria,1UE3Q@1239|Firmicutes,4HCUV@91061|Bacilli,26EMY@186818|Planococcaceae	91061|Bacilli	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158343_k127_2196063_1	292459.STH843	2.465e-40	161.0	COG2203@1|root,COG5002@1|root,COG5278@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
SRR25158343_k127_2230744_0	1688.BCUN_0265	1.14e-67	244.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,2I2GA@201174|Actinobacteria,4D07F@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
SRR25158343_k127_2230744_5	441620.Mpop_2665	1.906e-24	105.0	2E4R2@1|root,32ZJM@2|Bacteria,1N9RQ@1224|Proteobacteria,2UFU4@28211|Alphaproteobacteria,1JWM5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2230744_7	1437600.JDUI01000008_gene1336	1.453e-08	66.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
SRR25158343_k127_2230744_6	940282.CADQ01000022_gene2093	3.22e-09	68.0	2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RecT
SRR25158343_k127_2230744_4	1232449.BAHV02000018_gene1537	5.863e-26	112.0	2DZY9@1|root,32VN1@2|Bacteria,1VE0V@1239|Firmicutes,24P7G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2230744_10	1232410.KI421413_gene661	2.831e-06	53.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,43SE6@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response)	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158343_k127_2230744_9	1034347.CAHJ01000074_gene2789	6.313e-08	62.0	COG5482@1|root,COG5482@2|Bacteria,1V3FI@1239|Firmicutes,4HI6C@91061|Bacilli,1ZDPW@1386|Bacillus	91061|Bacilli	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2161
SRR25158343_k127_2230744_3	485918.Cpin_3879	3.677e-43	175.0	COG1783@1|root,COG1783@2|Bacteria,4PN7V@976|Bacteroidetes	976|Bacteroidetes	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_3,Terminase_6
SRR25158343_k127_2230744_11	945712.CULC22_01178	6.611e-06	59.0	COG4383@1|root,COG4383@2|Bacteria,2H8VW@201174|Actinobacteria,22JK7@1653|Corynebacteriaceae	201174|Actinobacteria	S	Mu-like prophage protein gp29	-	-	-	-	-	-	-	-	-	-	-	-	DUF935
SRR25158343_k127_2230744_8	56780.SYN_03379	5.952e-08	59.0	2CDSP@1|root,32RYD@2|Bacteria,1N213@1224|Proteobacteria,42U4H@68525|delta/epsilon subdivisions,2WQTU@28221|Deltaproteobacteria,2MSDT@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2230744_2	621372.ACIH01000097_gene2787	1.335e-50	190.0	COG4397@1|root,COG4397@2|Bacteria,1TSQ3@1239|Firmicutes,4I9KF@91061|Bacilli,271PY@186822|Paenibacillaceae	91061|Bacilli	S	Mu-like prophage major head subunit gpT	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_gpT
SRR25158343_k127_2230744_1	644966.Tmar_0048	1.054e-65	255.0	COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia	186801|Clostridia	M	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PhageMin_Tail
SRR25158343_k127_2230744_12	323097.Nham_3850	0.0002068	51.0	COG3210@1|root,COG3210@2|Bacteria,1PE7J@1224|Proteobacteria,2UZPP@28211|Alphaproteobacteria,3K4JU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_226741_9	698737.SLGD_02450	2.845e-15	83.0	COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli,4GXJR@90964|Staphylococcaceae	91061|Bacilli	M	Peptidoglycan hydrolase involved in the splitting of the septum during cell division	sle1	-	3.5.1.28	ko:K22409	-	-	-	-	ko00000,ko01000	-	CBM50	-	CHAP,LysM
SRR25158343_k127_226741_13	330084.JNYZ01000003_gene2298	0.0007327	51.0	28JC4@1|root,2Z96S@2|Bacteria,2IEPB@201174|Actinobacteria	201174|Actinobacteria	S	P22 coat protein-protein 5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
SRR25158343_k127_226741_12	697284.ERIC2_c26570	3.653e-05	54.0	2C4QM@1|root,32REC@2|Bacteria,1V795@1239|Firmicutes,4HXX2@91061|Bacilli,26Z03@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
SRR25158343_k127_226741_6	1206739.BAGJ01000051_gene5082	1.209e-23	111.0	2DMHA@1|root,32RIQ@2|Bacteria,2I8K6@201174|Actinobacteria,4G4KX@85025|Nocardiaceae	201174|Actinobacteria	S	Phage minor capsid protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Phage_min_cap2
SRR25158343_k127_226741_3	2754.EH55_06900	9.125e-44	178.0	28JFV@1|root,2Z99R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
SRR25158343_k127_226741_4	665950.HMPREF1025_01581	5.017e-41	170.0	COG5362@1|root,COG5362@2|Bacteria,1TSQB@1239|Firmicutes,24ACE@186801|Clostridia	186801|Clostridia	S	TIGRFAM Phage	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_226741_1	1395513.P343_08010	1.408e-86	302.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,26PCB@186821|Sporolactobacillaceae	91061|Bacilli	KL	PFAM DNA methylase N-4 N-6 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
SRR25158343_k127_226741_10	1340493.JNIF01000003_gene3703	1.906e-10	64.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158343_k127_226741_0	1121877.JQKF01000019_gene2594	1.717e-89	304.0	COG0463@1|root,COG0463@2|Bacteria,2GJ9C@201174|Actinobacteria	201174|Actinobacteria	M	Reversibly glycosylated polypeptide	-	-	-	-	-	-	-	-	-	-	-	-	RGP
SRR25158343_k127_226741_5	413816.BBJP01000006_gene395	1.468e-33	140.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23SHF@183963|Halobacteria	183963|Halobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158343_k127_226741_8	1449976.KALB_4695	4.325e-17	89.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	cbpD	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHAP,CW_binding_1,GBS_Bsp-like,SH3_5
SRR25158343_k127_226741_2	1027292.HMPREF9372_0959	1.977e-86	297.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli,26H3K@186818|Planococcaceae	91061|Bacilli	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_226741_7	1444310.JANV01000162_gene1220	9.001e-19	95.0	299WX@1|root,2ZWYS@2|Bacteria,1V4RB@1239|Firmicutes,4HRT6@91061|Bacilli,1ZHPN@1386|Bacillus	91061|Bacilli	S	ERF superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ERF
SRR25158343_k127_28398_17	391603.FBALC1_10642	1.068e-08	66.0	COG1443@1|root,COG1443@2|Bacteria,4NRS2@976|Bacteroidetes,1I2UY@117743|Flavobacteriia	976|Bacteroidetes	I	Hydrolase of MutT (Nudix) family protein	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_28398_18	1123075.AUDP01000011_gene1862	8.977e-06	56.0	COG0637@1|root,COG0637@2|Bacteria,1V1NW@1239|Firmicutes,24G37@186801|Clostridia,3WJ7V@541000|Ruminococcaceae	186801|Clostridia	S	subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,HAD_2
SRR25158343_k127_28398_16	317619.ANKN01000208_gene2051	7.451e-18	85.0	COG1598@1|root,COG1598@2|Bacteria,1G97T@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158343_k127_28398_0	13349.G1X601	1.404e-202	642.0	COG0766@1|root,2QV7D@2759|Eukaryota,38E4I@33154|Opisthokonta,3PEFV@4751|Fungi,3R423@4890|Ascomycota	4751|Fungi	E	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	EPSP_synthase
SRR25158343_k127_28398_1	1123400.KB904774_gene3265	2.729e-139	458.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,45ZMT@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158343_k127_28398_11	1206731.BAGB01000168_gene1298	6.124e-41	157.0	2AQGI@1|root,31FP2@2|Bacteria,2HJ9N@201174|Actinobacteria,4G5ZS@85025|Nocardiaceae	201174|Actinobacteria	S	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_28398_12	415426.Hbut_1358	7.674e-41	161.0	COG0464@1|root,arCOG01308@2157|Archaea,2XPPI@28889|Crenarchaeota	28889|Crenarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
SRR25158343_k127_28398_2	13349.G1X602	4.157e-130	423.0	COG0812@1|root,2QR6B@2759|Eukaryota,39ZJS@33154|Opisthokonta,3PDT8@4751|Fungi,3R3IT@4890|Ascomycota	4751|Fungi	M	Udp-n-acetylenolpyruvoylglucosamine reductase	-	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158343_k127_28398_15	1121372.AULK01000013_gene356	2.294e-18	98.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4FKB4@85023|Microbacteriaceae	201174|Actinobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158343_k127_28398_13	1155714.KB891988_gene1817	1.931e-39	156.0	COG1073@1|root,COG1073@2|Bacteria,2I4RK@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158343_k127_28398_7	326423.RBAM_034180	8.513e-53	188.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	ywkD	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158343_k127_28398_9	1122963.AUHB01000007_gene3697	8.496e-49	179.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	1.1.1.169,3.1.3.25,3.6.1.55	ko:K00077,ko:K01092,ko:K03574	ko00521,ko00562,ko00770,ko01100,ko01110,ko04070,map00521,map00562,map00770,map01100,map01110,map04070	M00119,M00131	R01185,R01186,R01187,R02472	RC00078,RC00726	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	NUDIX
SRR25158343_k127_28398_4	485913.Krac_12421	3.136e-62	216.0	COG2764@1|root,COG2764@2|Bacteria,2G7I7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRR25158343_k127_28398_5	243233.MCA0342	1.529e-61	231.0	COG0249@1|root,COG0249@2|Bacteria,1R85X@1224|Proteobacteria,1RYSC@1236|Gammaproteobacteria,1XE12@135618|Methylococcales	135618|Methylococcales	L	PFAM DNA mismatch repair protein MutS, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
SRR25158343_k127_28398_3	309801.trd_0813	6.558e-94	324.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,27XRP@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158343_k127_28398_10	1227499.C493_01575	1.829e-44	172.0	COG1121@1|root,arCOG00201@2157|Archaea,2XTEU@28890|Euryarchaeota,23SAC@183963|Halobacteria	183963|Halobacteria	E	COG1121 ABC-type Mn Zn transport systems, ATPase component	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158343_k127_28398_8	572480.Arnit_0679	2.591e-50	190.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2YMMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158343_k127_28398_6	383372.Rcas_0805	4.15e-54	218.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
SRR25158343_k127_337231_0	888743.HMPREF9141_1966	7.822e-16	86.0	COG0546@1|root,COG0546@2|Bacteria,4NNJ1@976|Bacteroidetes,2G32S@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158343_k127_341014_1	1140.Synpcc7942_0287	7.307e-36	145.0	COG1340@1|root,COG1340@2|Bacteria	2|Bacteria	KT	protein secretion by the type IV secretion system	potC	-	2.1.1.172,2.1.1.80,3.1.1.61	ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00207,M00299,M00506	R07234	RC00003	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1	-	-	Abhydrolase_8,BPD_transp_1,CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,Ion_trans_2,PAS_4,PhageMin_Tail
SRR25158343_k127_341014_3	1536773.R70331_21560	5.46e-08	55.0	COG0537@1|root,COG0537@2|Bacteria,1VSAZ@1239|Firmicutes,4HUKN@91061|Bacilli,26YC8@186822|Paenibacillaceae	91061|Bacilli	FG	Diadenosine tetraphosphate	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158343_k127_341014_2	426716.JOAJ01000005_gene2532	3.216e-21	103.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,4FU35@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3235)	rpfA	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0040008,GO:0040009,GO:0040010,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0060255,GO:0065007	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	DUF3235,Transglycosylas
SRR25158343_k127_341014_0	1121939.L861_16530	0.0	3058.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	VRP1
SRR25158343_k127_450603_5	926550.CLDAP_37440	1.896e-84	309.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158343_k127_450603_4	1122927.KB895417_gene3213	8.957e-90	312.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,26QDD@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158343_k127_450603_3	345341.KUTG_01907	9.415e-98	326.0	COG0500@1|root,COG2226@2|Bacteria,2IGXK@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_450603_1	1303518.CCALI_00246	2.396e-159	525.0	COG1200@1|root,COG1200@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158343_k127_450603_8	448385.sce8059	1.737e-28	121.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2YVK3@29|Myxococcales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158343_k127_450603_13	1410668.JNKC01000016_gene993	0.000703	42.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_450603_0	1408813.AYMG01000038_gene270	0.0	1214.0	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	2.1.1.72	ko:K03427,ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,HSDR_N_2,Methylase_S,N6_Mtase,TaqI_C
SRR25158343_k127_450603_12	1280676.AUJO01000001_gene2647	2.707e-10	67.0	2BUGF@1|root,32PSG@2|Bacteria,1VY5B@1239|Firmicutes,252HR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_450603_2	414996.IL38_17240	3.316e-101	344.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,409ZU@622450|Actinopolysporales	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158343_k127_450603_7	1304880.JAGB01000002_gene1880	1.766e-61	228.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158343_k127_450603_9	1122915.AUGY01000009_gene4815	1.33e-26	118.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,26QUX@186822|Paenibacillaceae	91061|Bacilli	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158343_k127_450603_10	904296.HMPREF9124_1095	9.426e-26	112.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,2PS8W@265975|Oribacterium	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158343_k127_450603_6	194439.CT1553	5.565e-70	243.0	COG0740@1|root,COG0740@2|Bacteria,1FDAQ@1090|Chlorobi	1090|Chlorobi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158343_k127_571577_35	28737.XP_006888430.1	0.0007437	51.0	COG2334@1|root,2QT7T@2759|Eukaryota,38G0M@33154|Opisthokonta,3BESY@33208|Metazoa,3CU55@33213|Bilateria,4891Z@7711|Chordata,48YI4@7742|Vertebrata,3JENX@40674|Mammalia,34UAT@311790|Afrotheria	33208|Metazoa	S	Hydroxylysine kinase	HYKK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006553,GO:0006554,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0047992,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.1.81	ko:K18201	ko00310,ko01100,map00310,map01100	-	R03378	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158343_k127_571577_10	177437.HRM2_08780	1.091e-39	153.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,42SQG@68525|delta/epsilon subdivisions,2WP5Y@28221|Deltaproteobacteria,2MK7A@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158343_k127_571577_31	1134474.O59_001763	3.718e-05	57.0	COG3420@1|root,COG3420@2|Bacteria,1R91N@1224|Proteobacteria,1RZ4P@1236|Gammaproteobacteria,1FHZW@10|Cellvibrio	1236|Gammaproteobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158343_k127_571577_23	700598.Niako_2938	3.799e-12	79.0	2DFCI@1|root,2ZRBH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_571577_14	519441.Smon_1069	1.134e-35	156.0	COG0125@1|root,COG0125@2|Bacteria,379MW@32066|Fusobacteria	32066|Fusobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158343_k127_571577_29	1507.HMPREF0262_02663	1.677e-06	61.0	COG0119@1|root,COG0119@2|Bacteria,1TRIK@1239|Firmicutes,249Q4@186801|Clostridia,36FTI@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158343_k127_571577_18	997829.HMPREF1121_00880	1.296e-26	113.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,2FT8J@200643|Bacteroidia,22YB1@171551|Porphyromonadaceae	976|Bacteroidetes	J	Has endoribonuclease activity on mRNA	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158343_k127_571577_1	319795.Dgeo_1794	3.515e-155	506.0	COG1171@1|root,COG1171@2|Bacteria,1WJZG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158343_k127_571577_7	33876.JNXY01000035_gene764	8.019e-63	242.0	COG0624@1|root,COG0624@2|Bacteria,2I9GD@201174|Actinobacteria,4DCBI@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158343_k127_571577_12	867845.KI911784_gene2506	5.226e-37	161.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,3756D@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158343_k127_571577_22	1211035.CD30_03380	4.986e-18	92.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3IXG3@400634|Lysinibacillus	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158343_k127_571577_15	882.DVU_2927	1.233e-33	134.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,42SHZ@68525|delta/epsilon subdivisions,2WPFZ@28221|Deltaproteobacteria,2MC0K@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158343_k127_571577_13	485913.Krac_2468	7.612e-37	143.0	COG0432@1|root,COG0432@2|Bacteria,2G9B9@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158343_k127_571577_17	1128421.JAGA01000002_gene415	1.149e-30	136.0	COG0568@1|root,COG0568@2|Bacteria,2NQNT@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_571577_5	1121428.DESHY_40088___1	1.45e-79	286.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,2602Z@186807|Peptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158343_k127_571577_2	635013.TherJR_2972	3.153e-141	462.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158343_k127_571577_25	663278.Ethha_0166	2.296e-09	62.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WJW1@541000|Ruminococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158343_k127_571577_9	1232436.CAPF01000083_gene839	3.518e-53	195.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CUFU@84998|Coriobacteriia	84998|Coriobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158343_k127_571577_21	997353.HMPREF9144_0421	2.788e-19	94.0	COG1051@1|root,COG1051@2|Bacteria,4NP2X@976|Bacteroidetes,2FMSZ@200643|Bacteroidia	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,zf-NADH-PPase
SRR25158343_k127_571577_20	575590.HMPREF0156_01437	9.906e-20	97.0	COG1051@1|root,COG1051@2|Bacteria,4NP2X@976|Bacteroidetes	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,zf-NADH-PPase
SRR25158343_k127_571577_19	926561.KB900623_gene1087	8.11e-24	114.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WAJB@53433|Halanaerobiales	186801|Clostridia	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_571577_4	1307761.L21SP2_0779	9.743e-83	293.0	COG0215@1|root,COG0215@2|Bacteria,2J618@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158343_k127_571577_11	1246995.AFR_40545	4.748e-39	160.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4D8Z9@85008|Micromonosporales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158343_k127_571577_3	471856.Jden_0448	4.443e-92	315.0	COG0438@1|root,COG0438@2|Bacteria,2GP0E@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_571577_6	1123355.JHYO01000032_gene11	3.135e-63	231.0	COG0438@1|root,COG0438@2|Bacteria,1PEAE@1224|Proteobacteria,2TRDN@28211|Alphaproteobacteria,370MI@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_571577_33	1123242.JH636436_gene634	7.506e-05	54.0	COG2267@1|root,COG2267@2|Bacteria,2IYU8@203682|Planctomycetes	203682|Planctomycetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158343_k127_571577_8	1348338.ADILRU_0956	6.206e-59	213.0	COG1876@1|root,COG1876@2|Bacteria,2IN2C@201174|Actinobacteria,4FPFY@85023|Microbacteriaceae	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158343_k127_571577_30	82654.Pse7367_0692	1.617e-05	50.0	2ESF9@1|root,33K00@2|Bacteria,1GGDN@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_571577_26	431943.CKL_1924	2.877e-08	61.0	COG5346@1|root,COG5346@2|Bacteria,1VK78@1239|Firmicutes,24QRV@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2335
SRR25158343_k127_571577_27	32057.KB217473_gene7785	1.449e-07	55.0	COG3677@1|root,COG3677@2|Bacteria,1GBBG@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158343_k127_571577_0	1123013.AUIC01000004_gene1695	2.953e-210	687.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4FKJ5@85023|Microbacteriaceae	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158343_k127_571577_16	1536772.R70723_15385	7.476e-32	129.0	COG1051@1|root,COG1051@2|Bacteria,1V6D5@1239|Firmicutes,4HJTU@91061|Bacilli,26XD5@186822|Paenibacillaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_571577_34	981223.AIED01000047_gene1413	0.000134	44.0	2AZTC@1|root,31S2K@2|Bacteria,1QPJP@1224|Proteobacteria,1TNA5@1236|Gammaproteobacteria,3NQ8M@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_59642_23	563040.Saut_2106	1.003e-05	54.0	COG2956@1|root,COG2956@2|Bacteria,1QUIS@1224|Proteobacteria,42M7G@68525|delta/epsilon subdivisions,2YMKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_7,TPR_8
SRR25158343_k127_59642_13	1380354.JIAN01000006_gene482	3.507e-28	126.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria	201174|Actinobacteria	NU	pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158343_k127_59642_2	639282.DEFDS_1109	2.699e-124	419.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158343_k127_59642_3	469381.Dpep_2276	5.725e-120	396.0	COG2805@1|root,COG2805@2|Bacteria,3T9Z7@508458|Synergistetes	508458|Synergistetes	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158343_k127_59642_5	379066.GAU_2568	5.418e-74	263.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158343_k127_59642_11	1280390.CBQR020000150_gene3997	5.924e-36	146.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli,26V43@186822|Paenibacillaceae	91061|Bacilli	NOU	peptidase	comC	-	3.4.23.43	ko:K02236,ko:K02654	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158343_k127_59642_27	1458427.BAWN01000015_gene932	0.0007132	48.0	COG4967@1|root,COG4967@2|Bacteria,1RK2M@1224|Proteobacteria,2VT1W@28216|Betaproteobacteria,4AEIG@80864|Comamonadaceae	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SRR25158343_k127_59642_6	1138822.PL11_04820	5.715e-54	201.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158343_k127_59642_9	1121272.KB903289_gene4134	9.221e-43	162.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4DDFU@85008|Micromonosporales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158343_k127_59642_22	1267533.KB906736_gene1044	4.823e-08	64.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria,2JIP1@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
SRR25158343_k127_59642_17	1396418.BATQ01000140_gene3203	1.667e-17	87.0	COG4974@1|root,COG4974@2|Bacteria,46WTJ@74201|Verrucomicrobia,2IUR5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR25158343_k127_59642_21	446470.Snas_0904	6.599e-10	69.0	COG3568@1|root,COG3568@2|Bacteria,2HF1S@201174|Actinobacteria,4F09Q@85014|Glycomycetales	2|Bacteria	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158343_k127_59642_18	33876.JNXY01000026_gene3503	4.358e-13	72.0	2EFVT@1|root,339N0@2|Bacteria,2GWUH@201174|Actinobacteria,4DGHW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_59642_4	633147.Olsu_0349	1.158e-87	311.0	COG5265@1|root,COG5265@2|Bacteria,2I6AF@201174|Actinobacteria,4CUQX@84998|Coriobacteriia	84998|Coriobacteriia	O	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_59642_7	1203622.HMPREF1290_01539	1.663e-53	203.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,22KIM@1653|Corynebacteriaceae	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	GO:0000988,GO:0000990,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009405,GO:0009415,GO:0009628,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016020,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0043254,GO:0044087,GO:0044419,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_59642_1	1123013.AUIC01000007_gene192	8.3e-126	421.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_59642_20	582515.KR51_00033050	5.322e-10	67.0	COG1327@1|root,COG1327@2|Bacteria,1G5PE@1117|Cyanobacteria	1117|Cyanobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158343_k127_59642_0	1121930.AQXG01000003_gene2749	3.378e-160	524.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158343_k127_59642_14	3983.cassava4.1_033949m	5.581e-24	109.0	28N75@1|root,2QUSF@2759|Eukaryota,37HS3@33090|Viridiplantae,3G9DW@35493|Streptophyta,4JG68@91835|fabids	35493|Streptophyta	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
SRR25158343_k127_59642_16	525904.Tter_0337	1.378e-18	89.0	COG3695@1|root,COG3695@2|Bacteria,2NRVD@2323|unclassified Bacteria	2|Bacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158343_k127_59642_8	1211819.CALK01000046_gene1747	1.647e-52	196.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,3VP3J@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158343_k127_59642_25	1245469.S58_71890	0.0001933	51.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2UJPY@28211|Alphaproteobacteria,3K4AT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158343_k127_59642_15	673860.AciM339_0030	1.434e-20	99.0	COG2220@1|root,arCOG00497@2157|Archaea,2XZBG@28890|Euryarchaeota,3F2Q1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158343_k127_59642_19	1408439.JHXW01000016_gene79	2.248e-12	69.0	COG0227@1|root,COG0227@2|Bacteria,37AJS@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158343_k127_59642_12	936455.KI421499_gene3443	5.919e-31	130.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2TRIF@28211|Alphaproteobacteria,3JT09@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Peptidase M50	MA20_27160	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158343_k127_59642_10	760142.Hipma_0827	1.837e-36	156.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_607696_7	1206744.BAGL01000044_gene991	2.238e-29	133.0	2BGS1@1|root,32AR6@2|Bacteria,2HH86@201174|Actinobacteria,4FUNW@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_607696_2	273068.TTE1344	4.272e-85	297.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158343_k127_607696_3	641524.ADICYQ_0300	1.248e-79	280.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
SRR25158343_k127_607696_0	563192.HMPREF0179_03201	3.814e-143	465.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
SRR25158343_k127_607696_1	429009.Adeg_0202	5.077e-132	444.0	COG3387@1|root,COG3387@2|Bacteria,1TSFD@1239|Firmicutes,24EW4@186801|Clostridia,42F5M@68295|Thermoanaerobacterales	186801|Clostridia	G	glycoside hydrolase 15-related	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
SRR25158343_k127_607696_8	416870.llmg_0098	1.891e-10	63.0	COG0267@1|root,COG0267@2|Bacteria,1U2G9@1239|Firmicutes,4IC2F@91061|Bacilli,1YBUF@1357|Lactococcus	91061|Bacilli	J	structural constituent of ribosome	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158343_k127_607696_6	590998.Celf_0320	1.04e-42	162.0	COG0494@1|root,COG0494@2|Bacteria,2GKUV@201174|Actinobacteria,4F2CI@85016|Cellulomonadaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_607696_5	1123020.AUIE01000040_gene4508	2.531e-43	160.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,1YJSX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158343_k127_608091_0	645991.Sgly_0384	0.0	1191.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25ZXZ@186807|Peptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158343_k127_608091_1	383372.Rcas_1597	0.0	1054.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,374SV@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158343_k127_608091_2	1121344.JHZO01000004_gene1221	7.227e-53	190.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158343_k127_608091_3	352165.HMPREF7215_0920	1.516e-43	164.0	COG0049@1|root,COG0049@2|Bacteria,3TAVX@508458|Synergistetes	508458|Synergistetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158343_k127_641032_1	2074.JNYD01000017_gene4360	9.867e-112	370.0	COG3491@1|root,COG3491@2|Bacteria,2IFWJ@201174|Actinobacteria,4EAFK@85010|Pseudonocardiales	201174|Actinobacteria	C	non-haem dioxygenase in morphine synthesis N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
SRR25158343_k127_641032_0	28042.GU90_11225	2.332e-115	379.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4DXKF@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158343_k127_641032_8	296591.Bpro_4770	3.077e-46	171.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VSAQ@28216|Betaproteobacteria,4AEGJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158343_k127_641032_23	397291.C804_01022	6.385e-10	63.0	COG2336@1|root,COG2336@2|Bacteria,1VHRI@1239|Firmicutes,24RYI@186801|Clostridia,27PT4@186928|unclassified Lachnospiraceae	186801|Clostridia	T	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158343_k127_641032_14	697282.Mettu_1892	5.083e-30	122.0	COG2337@1|root,COG2337@2|Bacteria,1PVJ9@1224|Proteobacteria,1TM47@1236|Gammaproteobacteria,1XGTH@135618|Methylococcales	2|Bacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	chpA	GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158343_k127_641032_28	1121286.AUMT01000004_gene795	3.972e-07	54.0	COG1403@1|root,COG1403@2|Bacteria,4NW50@976|Bacteroidetes,1IB5W@117743|Flavobacteriia	976|Bacteroidetes	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR25158343_k127_641032_26	1394178.AWOO02000089_gene1099	2.922e-08	62.0	COG0500@1|root,COG2226@2|Bacteria,2IJED@201174|Actinobacteria,4EP6P@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158343_k127_641032_13	1041930.Mtc_0377	9.795e-32	132.0	COG0135@1|root,arCOG01983@2157|Archaea,2XXCM@28890|Euryarchaeota,2NBIJ@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158343_k127_641032_19	857087.Metme_3454	1.843e-20	93.0	COG2026@1|root,COG2026@2|Bacteria,1QCBC@1224|Proteobacteria,1SFK3@1236|Gammaproteobacteria,1XGPR@135618|Methylococcales	135618|Methylococcales	DJ	TIGRFAM Addiction module toxin, RelE StbE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158343_k127_641032_25	933262.AXAM01000006_gene1850	6.634e-09	59.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,42WJ7@68525|delta/epsilon subdivisions,2WRB6@28221|Deltaproteobacteria,2MP47@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_641032_32	1382356.JQMP01000003_gene1519	0.0006879	45.0	COG2258@1|root,COG2258@2|Bacteria,2G7HE@200795|Chloroflexi,27YRB@189775|Thermomicrobia	189775|Thermomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158343_k127_641032_15	485913.Krac_9592	8.755e-27	113.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20,HTH_5,Methyltransf_11
SRR25158343_k127_641032_9	665959.HMPREF1013_03184	6.874e-40	153.0	COG3832@1|root,COG3832@2|Bacteria,1V352@1239|Firmicutes,4HIVF@91061|Bacilli,1ZDWI@1386|Bacillus	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158343_k127_641032_18	479434.Sthe_0865	8.167e-23	103.0	COG1661@1|root,COG1661@2|Bacteria	2|Bacteria	O	DNA-binding protein with PD1-like DNA-binding motif	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR25158343_k127_641032_11	203123.OEOE_0214	6.125e-37	147.0	COG2173@1|root,COG2173@2|Bacteria,1V76X@1239|Firmicutes,4HINF@91061|Bacilli,4AXQI@81850|Leuconostocaceae	91061|Bacilli	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158343_k127_641032_17	768671.ThimaDRAFT_0495	3.994e-26	116.0	COG4678@1|root,COG4678@2|Bacteria,1MXCR@1224|Proteobacteria,1RPZR@1236|Gammaproteobacteria,1WW1Z@135613|Chromatiales	135613|Chromatiales	G	PFAM TraG-like protein, N-terminal region	-	-	-	ko:K12056	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraG_N
SRR25158343_k127_641032_5	1380370.JIBA01000018_gene533	9.991e-54	192.0	2CHCP@1|root,32S5R@2|Bacteria,2IRB0@201174|Actinobacteria,4FHN7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158343_k127_641032_4	1220535.IMCC14465_15080	3.579e-58	216.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,2VCCD@28211|Alphaproteobacteria,4BPDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158343_k127_641032_29	1116231.SMA_0814	1.048e-05	55.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli	91061|Bacilli	F	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR25158343_k127_641032_27	1122137.AQXF01000001_gene3367	6.473e-08	55.0	COG3102@1|root,COG3102@2|Bacteria	2|Bacteria	S	YecM protein	yecM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09907	-	-	-	-	ko00000	-	-	-	YecM
SRR25158343_k127_641032_30	1122137.AQXF01000001_gene3367	3.421e-05	49.0	COG3102@1|root,COG3102@2|Bacteria	2|Bacteria	S	YecM protein	yecM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09907	-	-	-	-	ko00000	-	-	-	YecM
SRR25158343_k127_641032_31	748671.LCRIS_01791	0.0001525	47.0	29QEZ@1|root,30BEA@2|Bacteria,1U7ZS@1239|Firmicutes,4IHX6@91061|Bacilli,3FAD5@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_641032_2	257310.BB2490	9.633e-111	378.0	COG2159@1|root,COG2159@2|Bacteria,1R8PV@1224|Proteobacteria,2VQ4H@28216|Betaproteobacteria,3T50B@506|Alcaligenaceae	28216|Betaproteobacteria	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
SRR25158343_k127_641032_3	485913.Krac_3987	6.419e-61	211.0	COG4898@1|root,COG4898@2|Bacteria,2G6Z7@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
SRR25158343_k127_641032_12	1122176.KB903542_gene361	7.267e-33	145.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1ISNT@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S10	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRR25158343_k127_641032_21	1123252.ATZF01000001_gene1546	8.401e-16	85.0	COG1051@1|root,COG1051@2|Bacteria,1UWW9@1239|Firmicutes,4HPVD@91061|Bacilli,27CZB@186824|Thermoactinomycetaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_641032_20	55529.EKX43619	1.206e-19	98.0	2ES2T@1|root,2SUR4@2759|Eukaryota	2759|Eukaryota	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158343_k127_641032_10	1206737.BAGF01000062_gene4081	1.258e-37	144.0	COG4319@1|root,COG4319@2|Bacteria,2I7Q3@201174|Actinobacteria,4G9V6@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158343_k127_641032_24	1547437.LL06_22320	8.437e-10	69.0	2DNR3@1|root,32YQ5@2|Bacteria,1N6UX@1224|Proteobacteria,2UG7C@28211|Alphaproteobacteria,43QE9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158343_k127_641032_6	1267535.KB906767_gene4484	9.629e-49	184.0	293T3@1|root,2ZR8H@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
SRR25158343_k127_641032_16	1150600.ADIARSV_1222	8.95e-27	115.0	COG3177@1|root,COG3177@2|Bacteria,4NSD2@976|Bacteroidetes,1J08H@117747|Sphingobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Penicillinase_R
SRR25158343_k127_77961_0	1235790.C805_00061	3.84e-19	92.0	2DZY9@1|root,32VN1@2|Bacteria,1VE0V@1239|Firmicutes,24P7G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_878580_42	1229172.JQFA01000004_gene524	1.283e-06	56.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,1H77Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,Response_reg
SRR25158343_k127_878580_37	1122137.AQXF01000001_gene3147	6.11e-08	63.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158343_k127_878580_34	8090.ENSORLP00000016029	2.48e-12	74.0	COG0500@1|root,KOG4058@2759|Eukaryota,39SC5@33154|Opisthokonta,3BDSU@33208|Metazoa,3CX4A@33213|Bilateria,488H1@7711|Chordata,4931R@7742|Vertebrata,49S9D@7898|Actinopterygii	33208|Metazoa	Q	Family with sequence similarity 173, member B	FAM173B	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016020,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0019866,GO:0030061,GO:0031090,GO:0031644,GO:0031646,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044057,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0048518,GO:0050789,GO:0051239,GO:0051240,GO:0051930,GO:0051931,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1904058	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_878580_47	323259.Mhun_3008	0.0008835	45.0	COG1722@1|root,arCOG03646@2157|Archaea	2157|Archaea	L	PFAM Exonuclease VII small subunit	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158343_k127_878580_15	314230.DSM3645_22876	3.759e-57	213.0	COG1570@1|root,COG1570@2|Bacteria,2IXGG@203682|Planctomycetes	203682|Planctomycetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158343_k127_878580_28	1101188.KI912155_gene1498	3.64e-23	111.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
SRR25158343_k127_878580_31	1343739.PAP_07460	7.211e-17	93.0	COG1041@1|root,arCOG00047@2157|Archaea,2Y2EJ@28890|Euryarchaeota,2432J@183968|Thermococci	183968|Thermococci	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
SRR25158343_k127_878580_32	690850.Desaf_1981	5.388e-15	78.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MCGT@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158343_k127_878580_14	1378168.N510_02923	4.018e-60	223.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes	1239|Firmicutes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_878580_29	1303518.CCALI_00427	1.31e-22	102.0	COG0745@1|root,COG0745@2|Bacteria	1303518.CCALI_00427|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
SRR25158343_k127_878580_1	1105031.HMPREF1141_1649	1.134e-174	562.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,36DBK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
SRR25158343_k127_878580_7	1274524.BSONL12_01202	5.672e-78	276.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
SRR25158343_k127_878580_30	649831.L083_2527	1.199e-20	105.0	COG3942@1|root,COG3942@2|Bacteria,2GR17@201174|Actinobacteria	201174|Actinobacteria	V	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
SRR25158343_k127_878580_24	485916.Dtox_3965	4.027e-29	128.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,2611R@186807|Peptococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158343_k127_878580_8	1235793.C809_03313	5.846e-78	266.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,27IGZ@186928|unclassified Lachnospiraceae	186801|Clostridia	D	ATPases associated with a variety of cellular activities	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158343_k127_878580_17	391616.OA238_c24740	7.22e-40	160.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	1224|Proteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158343_k127_878580_27	1423743.JCM14108_259	3.783e-25	118.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_878580_40	12957.ACEP14011-PA	4.364e-07	58.0	COG0464@1|root,KOG0733@2759|Eukaryota,38CEF@33154|Opisthokonta,3BADF@33208|Metazoa,3CV7U@33213|Bilateria,41USS@6656|Arthropoda,3SJ0S@50557|Insecta,46JGP@7399|Hymenoptera	33208|Metazoa	O	Nucleolin binding domain	NVL	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005697,GO:0005730,GO:0006950,GO:0007154,GO:0008144,GO:0008150,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010556,GO:0010557,GO:0010604,GO:0010876,GO:0010941,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019915,GO:0022613,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033554,GO:0035639,GO:0036094,GO:0042254,GO:0042594,GO:0042981,GO:0043021,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044877,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048582,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051094,GO:0051171,GO:0051173,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051338,GO:0051347,GO:0051716,GO:0051972,GO:0051973,GO:0060255,GO:0060548,GO:0061062,GO:0061063,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071496,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990275,GO:1990904,GO:2000026,GO:2000112,GO:2000278,GO:2000573	-	ko:K14571	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	AAA,Nucleolin_bd
SRR25158343_k127_878580_48	93059.P9211_09061	0.0008945	50.0	COG0465@1|root,COG0465@2|Bacteria,1G1S2@1117|Cyanobacteria,1MKUM@1212|Prochloraceae	1117|Cyanobacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH4	GO:0003674,GO:0003824,GO:0004176,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0010206,GO:0010304,GO:0015979,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031323,GO:0031324,GO:0042548,GO:0042623,GO:0043155,GO:0043170,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158343_k127_878580_45	926560.KE387027_gene756	0.0004464	51.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
SRR25158343_k127_878580_4	765420.OSCT_1746	2.91e-105	353.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,374TI@32061|Chloroflexia	32061|Chloroflexia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158343_k127_878580_33	317025.Tcr_1940	1.729e-12	79.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,45ZZU@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_878580_0	305900.GV64_18745	9.011e-222	716.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XIDI@135619|Oceanospirillales	135619|Oceanospirillales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158343_k127_878580_39	1033734.CAET01000039_gene307	3.049e-07	59.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1ZFW8@1386|Bacillus	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158343_k127_878580_6	370438.PTH_0013	2.202e-81	287.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,260VV@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158343_k127_878580_9	237368.SCABRO_00086	7.089e-73	257.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_24,PDDEXK_1
SRR25158343_k127_878580_16	221288.JH992901_gene5711	1.524e-41	162.0	COG0546@1|root,COG0546@2|Bacteria,1G52P@1117|Cyanobacteria,1JJNM@1189|Stigonemataceae	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	cbbZp	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158343_k127_878580_25	590998.Celf_0320	1.804e-27	116.0	COG0494@1|root,COG0494@2|Bacteria,2GKUV@201174|Actinobacteria,4F2CI@85016|Cellulomonadaceae	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_878580_44	1499967.BAYZ01000097_gene4351	4.044e-05	54.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,PKD,VWA
SRR25158343_k127_878580_22	518766.Rmar_0203	2.594e-33	136.0	2BVXG@1|root,32UI7@2|Bacteria,4PEMY@976|Bacteroidetes,1FJBH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
SRR25158343_k127_878580_36	7070.TC002057-PA	3.118e-08	66.0	COG0334@1|root,KOG2250@2759|Eukaryota,38GEK@33154|Opisthokonta,3BHQW@33208|Metazoa,3CSIC@33213|Bilateria,41TCT@6656|Arthropoda,3SFMK@50557|Insecta	33208|Metazoa	E	Belongs to the Glu Leu Phe Val dehydrogenases family	GLUD1	GO:0000166,GO:0001882,GO:0001883,GO:0002791,GO:0002793,GO:0003008,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006082,GO:0006103,GO:0006106,GO:0006116,GO:0006139,GO:0006520,GO:0006536,GO:0006537,GO:0006538,GO:0006541,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009117,GO:0009987,GO:0010035,GO:0010038,GO:0010044,GO:0010646,GO:0010647,GO:0010817,GO:0016020,GO:0016053,GO:0016054,GO:0016491,GO:0016597,GO:0016638,GO:0016639,GO:0017076,GO:0019001,GO:0019362,GO:0019551,GO:0019637,GO:0019674,GO:0019752,GO:0019866,GO:0019899,GO:0021549,GO:0022037,GO:0023051,GO:0023056,GO:0030554,GO:0030902,GO:0031090,GO:0031406,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032024,GO:0032501,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032879,GO:0032880,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046883,GO:0046887,GO:0048037,GO:0048513,GO:0048518,GO:0048522,GO:0048731,GO:0048856,GO:0050662,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0050796,GO:0050877,GO:0050890,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051186,GO:0051222,GO:0051223,GO:0051287,GO:0055086,GO:0055114,GO:0060322,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0070403,GO:0070728,GO:0071704,GO:0072350,GO:0072524,GO:0090087,GO:0090276,GO:0090277,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1903530,GO:1903532,GO:1904951	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158343_k127_878580_21	471223.GWCH70_1293	2.336e-33	134.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli,1WGIJ@129337|Geobacillus	91061|Bacilli	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
SRR25158343_k127_878580_46	521011.Mpal_1435	0.0004643	48.0	COG0537@1|root,arCOG00419@2157|Archaea,2Y0J5@28890|Euryarchaeota,2NA21@224756|Methanomicrobia	224756|Methanomicrobia	F	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158343_k127_878580_5	679926.Mpet_0738	2.254e-95	331.0	COG1384@1|root,arCOG00485@2157|Archaea,2XTR5@28890|Euryarchaeota,2N9FV@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158343_k127_878580_23	1121344.JHZO01000004_gene1233	1.237e-30	126.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3WIJW@541000|Ruminococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158343_k127_878580_2	574087.Acear_0370	3.173e-134	448.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,3WAH2@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158343_k127_878580_35	113395.AXAI01000004_gene4498	2.265e-11	74.0	COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,2TTX7@28211|Alphaproteobacteria,3JSCR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158343_k127_878580_20	1321814.HMPREF9089_00530	1.616e-33	143.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25VUG@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158343_k127_878580_12	42256.RradSPS_1408	7.445e-64	226.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158343_k127_878580_18	1216007.AOPM01000111_gene347	3.757e-38	149.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,2Q0S4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158343_k127_878580_13	608506.COB47_1628	2.684e-60	214.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158343_k127_878580_11	2340.JV46_15070	1.447e-64	228.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1J5AE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158343_k127_878580_10	1121382.JQKG01000014_gene253	3.028e-72	256.0	COG2899@1|root,COG2899@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
SRR25158343_k127_878580_26	880074.BARVI_09815	2.791e-27	115.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,2FTUG@200643|Bacteroidia,22YDW@171551|Porphyromonadaceae	976|Bacteroidetes	J	50S ribosomal protein L31 type B	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158343_k127_878580_3	525904.Tter_1654	1.779e-113	378.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158343_k127_878580_19	552811.Dehly_0967	6.36e-34	141.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi,34CQQ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158343_k127_878580_41	1499967.BAYZ01000080_gene910	1.235e-06	63.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2NRZP@2323|unclassified Bacteria	2|Bacteria	M	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,ESPR,LVIVD,YadA_anchor,YadA_head,YadA_stalk
SRR25158343_k127_887593_0	1382356.JQMP01000003_gene1305	2.492e-75	265.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,27XP2@189775|Thermomicrobia	189775|Thermomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR25158343_k127_887593_2	172088.AUGA01000046_gene1308	1.824e-26	116.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,3JTAJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630	-	R00653	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	Pep_deformylase
SRR25158343_k127_887593_1	648996.Theam_0215	1.227e-46	181.0	COG0223@1|root,COG0223@2|Bacteria,2G3PD@200783|Aquificae	200783|Aquificae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158343_k127_887593_3	350058.Mvan_5961	8.747e-09	64.0	2B9ZR@1|root,323DD@2|Bacteria,2H80V@201174|Actinobacteria,23E7J@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_90500_0	68170.KL590507_gene9563	2.332e-06	52.0	2DKBJ@1|root,32UET@2|Bacteria,2IIG6@201174|Actinobacteria,4E63I@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_978250_4	717231.Flexsi_1822	7.608e-47	174.0	COG0231@1|root,COG0231@2|Bacteria,2GEJZ@200930|Deferribacteres	200930|Deferribacteres	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158343_k127_978250_8	1127696.HMPREF9134_00383	1.375e-10	63.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,2FT22@200643|Bacteroidia,22Y4P@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158343_k127_978250_5	1353529.M899_1251	2.055e-30	125.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2MT2P@213481|Bdellovibrionales,2WNAN@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158343_k127_978250_7	676032.FN3523_1056	9.18e-17	85.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,460SS@72273|Thiotrichales	72273|Thiotrichales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158343_k127_978250_1	657322.FPR_01960	2.808e-147	492.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158343_k127_978250_2	1304284.L21TH_1990	5.088e-129	437.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158343_k127_978250_3	525904.Tter_0795	2.715e-50	185.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158343_k127_978250_0	903814.ELI_2063	8.105e-208	669.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25V7M@186806|Eubacteriaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158343_k127_978250_6	113355.CM001775_gene2886	1.217e-23	103.0	COG0184@1|root,COG0184@2|Bacteria,1G7NP@1117|Cyanobacteria	1117|Cyanobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158343_k127_982352_2	580331.Thit_2014	1.12e-235	754.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158343_k127_982352_19	1382315.JPOI01000001_gene2946	5.344e-91	313.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1WG3Q@129337|Geobacillus	91061|Bacilli	K	Participates in both transcription termination and antitermination	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158343_k127_982352_5	416870.llmg_0319	9.417e-201	654.0	COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,1YB3M@1357|Lactococcus	91061|Bacilli	E	Aminopeptidase with broad substrate specificity to several peptides. It has more affinity for oligopeptides than for dipeptides. It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover	pepN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158343_k127_982352_65	1408437.JNJN01000037_gene432	2.234e-12	74.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,25X8A@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158343_k127_982352_32	1121949.AQXT01000002_gene3019	6.525e-44	168.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,43XM1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158343_k127_982352_51	592031.GCWU000322_00102	2.43e-25	111.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158343_k127_982352_8	1121104.AQXH01000001_gene2104	3.324e-130	426.0	COG0281@1|root,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,PTA_PTB,malic
SRR25158343_k127_982352_22	673862.BABL1_374	1.213e-75	274.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158343_k127_982352_33	43354.JOIJ01000006_gene1884	6.709e-40	154.0	COG0566@1|root,COG0566@2|Bacteria,2HRZ2@201174|Actinobacteria,4EBF4@85010|Pseudonocardiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158343_k127_982352_58	1449347.JQLN01000007_gene1553	1.943e-16	91.0	COG2340@1|root,COG2340@2|Bacteria,2I39U@201174|Actinobacteria	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158343_k127_982352_0	1121346.KB899810_gene1510	1.969e-271	878.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158343_k127_982352_76	1217720.ALOX01000090_gene3433	4.187e-05	55.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria,2JQDC@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_S11,SPOR
SRR25158343_k127_982352_73	500633.CLOHIR_00894	2.125e-06	55.0	COG4980@1|root,COG4980@2|Bacteria,1VK4M@1239|Firmicutes,24VID@186801|Clostridia	186801|Clostridia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR25158343_k127_982352_21	485913.Krac_5164	3.688e-83	285.0	COG1210@1|root,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158343_k127_982352_15	1304880.JAGB01000001_gene694	1.484e-108	369.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158343_k127_982352_7	748449.Halha_2302	7.259e-137	449.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3WA7Q@53433|Halanaerobiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158343_k127_982352_62	1045004.OKIT_0256	4.111e-14	75.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,4AXWV@81850|Leuconostocaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158343_k127_982352_1	479434.Sthe_0796	2.263e-263	826.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158343_k127_982352_43	314345.SPV1_10621	8.688e-31	129.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
SRR25158343_k127_982352_64	742733.HMPREF9469_02301	4.646e-13	80.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,220DS@1506553|Lachnoclostridium	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158343_k127_982352_18	1163408.UU9_03218	2.268e-93	317.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1X34A@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the class I fructose-bisphosphate aldolase family	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR25158343_k127_982352_9	1121924.ATWH01000014_gene3393	4.572e-129	420.0	COG3958@1|root,COG3958@2|Bacteria,2I8VM@201174|Actinobacteria,4FKW5@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158343_k127_982352_16	1121924.ATWH01000014_gene3392	1.223e-99	332.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria,4FN7S@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158343_k127_982352_54	525309.HMPREF0494_1835	1.972e-18	93.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158343_k127_982352_46	469371.Tbis_2531	4.351e-29	124.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4E2S1@85010|Pseudonocardiales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158343_k127_982352_11	1203556.HMPREF1478_01795	1.507e-119	395.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D318@85005|Actinomycetales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158343_k127_982352_40	1123013.AUIC01000004_gene1752	3.024e-31	130.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3067,iE2348C_1286.E2348C_3641,iECABU_c1320.ECABU_c38150,iECED1_1282.ECED1_4056,iECNA114_1301.ECNA114_3494,iECOK1_1307.ECOK1_3810,iECP_1309.ECP_3483,iECS88_1305.ECS88_3783,iECSF_1327.ECSF_3218,iLF82_1304.LF82_1531,iNRG857_1313.NRG857_16815,iUMN146_1321.UM146_17040,iUTI89_1310.UTI89_C3895,ic_1306.c4167	NUDIX
SRR25158343_k127_982352_77	1089545.KB913037_gene2792	5.363e-05	51.0	COG1051@1|root,COG1051@2|Bacteria,2IMQZ@201174|Actinobacteria,4EF1D@85010|Pseudonocardiales	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158343_k127_982352_23	259536.Psyc_1296	4.434e-73	250.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,3NJX9@468|Moraxellaceae	1236|Gammaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iJN746.PP_0538,iPC815.YPO3521	Pyrophosphatase
SRR25158343_k127_982352_55	1285586.H131_20942	5.19e-18	93.0	COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UGF1@1239|Firmicutes,4HBM4@91061|Bacilli,3IWSP@400634|Lysinibacillus	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
SRR25158343_k127_982352_39	1040983.AXAE01000004_gene820	3.291e-32	135.0	COG1018@1|root,COG1018@2|Bacteria,1PEWB@1224|Proteobacteria,2UGW8@28211|Alphaproteobacteria,43QTP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	NQR2, RnfD, RnfE family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1,NQR2_RnfD_RnfE
SRR25158343_k127_982352_20	264732.Moth_2420	2.006e-84	290.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_982352_69	1347392.CCEZ01000009_gene2337	4.176e-09	60.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158343_k127_982352_49	1229780.BN381_350110	1.583e-26	116.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,3UWVE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158343_k127_982352_6	1304865.JAGF01000001_gene3962	1.015e-183	592.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_982352_3	1122182.KB903833_gene5566	1.863e-205	670.0	COG3409@1|root,COG3409@2|Bacteria,2H4NG@201174|Actinobacteria	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_982352_17	929506.CbC4_0959	9.921e-97	347.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,36DSY@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR25158343_k127_982352_35	215803.DB30_1656	1.512e-37	147.0	COG0537@1|root,COG0537@2|Bacteria,1R7GK@1224|Proteobacteria	1224|Proteobacteria	FG	diadenosine tetraphosphate	hit	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158343_k127_982352_74	290512.Paes_1776	4.384e-06	54.0	2DNS7@1|root,32YWC@2|Bacteria,1FFKA@1090|Chlorobi	1090|Chlorobi	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158343_k127_982352_24	385682.AFSL01000055_gene430	2.698e-71	253.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,3XIT0@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class II core domain (F)	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158343_k127_982352_37	1451261.AS96_06990	6.345e-34	136.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4FNDQ@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF520)	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158343_k127_982352_14	298654.FraEuI1c_1162	6.502e-110	371.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4ESP9@85013|Frankiales	201174|Actinobacteria	G	Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
SRR25158343_k127_982352_36	1541960.KQ78_02072	5.885e-36	151.0	COG1322@1|root,COG1322@2|Bacteria,3WTE9@544448|Tenericutes	544448|Tenericutes	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158343_k127_982352_68	1380347.JNII01000007_gene331	6.496e-10	64.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF3703,PAP2
SRR25158343_k127_982352_30	1394176.AWUO01000001_gene1161	1.033e-51	189.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4D0W1@85004|Bifidobacteriales	201174|Actinobacteria	L	Methylpurine-DNA glycosylase (MPG)	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158343_k127_982352_50	479434.Sthe_1164	1.393e-25	112.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,27YGT@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158343_k127_982352_48	693746.OBV_17850	4.581e-27	112.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158343_k127_982352_4	485913.Krac_10794	1.043e-202	647.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_982352_44	1150399.AQYK01000002_gene3179	8.918e-31	135.0	COG1664@1|root,COG1664@2|Bacteria,2H52M@201174|Actinobacteria	201174|Actinobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_982352_13	641107.CDLVIII_0077	2.127e-111	375.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,36EXD@31979|Clostridiaceae	186801|Clostridia	L	AAA ATPase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158343_k127_982352_12	519989.ECTPHS_09687	1.493e-116	387.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1WVWR@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158343_k127_982352_10	289377.HL41_06580	4.216e-121	420.0	COG0474@1|root,COG0474@2|Bacteria,2GGR5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158343_k127_982352_26	760142.Hipma_0827	1.303e-60	227.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_982352_78	879212.DespoDRAFT_01679	0.0002029	53.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,43B47@68525|delta/epsilon subdivisions,2X6I0@28221|Deltaproteobacteria,2MPUU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
SRR25158343_k127_982352_34	1120978.KB894083_gene914	8.494e-40	163.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,4HC9M@91061|Bacilli,27HZ9@186828|Carnobacteriaceae	91061|Bacilli	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
SRR25158343_k127_982352_66	1121468.AUBR01000041_gene1711	3.979e-12	78.0	29D8E@1|root,3006C@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4417)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4417
SRR25158343_k127_982352_72	714083.JH370377_gene1708	5.011e-07	59.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4FKD4@85023|Microbacteriaceae	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158343_k127_982352_53	992406.RIA_0339	4.486e-20	103.0	COG3012@1|root,COG3012@2|Bacteria,4NMKK@976|Bacteroidetes,1I1MV@117743|Flavobacteriia	976|Bacteroidetes	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_982352_31	910313.HMPREF9320_1635	2.56e-50	189.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,Shikimate_DH,Shikimate_dh_N
SRR25158343_k127_982352_38	1116232.AHBF01000001_gene6010	7.219e-34	141.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158343_k127_982352_47	910313.HMPREF9320_1632	5.069e-28	126.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158343_k127_982352_56	877455.Metbo_2196	1.155e-17	91.0	COG0207@1|root,arCOG03214@2157|Archaea,2XYEP@28890|Euryarchaeota,23P47@183925|Methanobacteria	183925|Methanobacteria	F	Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRR25158343_k127_982352_52	1122933.JNIY01000012_gene1319	4.123e-23	109.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DZR,Helicase_C,PLDc_N,Pribosyltran,ResIII
SRR25158343_k127_982352_42	641491.DND132_3374	4.78e-31	130.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MBDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	hydrolase, HAD-superfamily, subfamily IIIA	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158343_k127_982352_79	1120950.KB892757_gene6552	0.0003158	49.0	295RB@1|root,2ZT2P@2|Bacteria,2GSR0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158343_k127_982352_57	243232.MJ_0226	1.204e-17	90.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,23QP7@183939|Methanococci	183939|Methanococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158343_k127_982352_67	188626.HMPREF0321_2909	2.077e-11	74.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	KorB,ParBc,RepB
SRR25158343_k127_982352_28	178901.AmDm5_1268	1.332e-55	211.0	COG1961@1|root,COG1961@2|Bacteria,1MV0C@1224|Proteobacteria,2TSYH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
SRR25158343_k127_982352_27	573370.DMR_15210	1.024e-55	204.0	28M2G@1|root,2ZAGX@2|Bacteria,1QDCH@1224|Proteobacteria,42UN0@68525|delta/epsilon subdivisions,2WWWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR25158343_k127_982352_41	203119.Cthe_3048	3.534e-31	126.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158343_k127_982352_59	1210884.HG799466_gene12357	4.994e-16	79.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
SRR25158343_k127_982352_70	469383.Cwoe_1968	8.396e-08	64.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,KAP_NTPase
SRR25158343_k127_982352_60	428125.CLOLEP_01900	8.375e-16	83.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1UNF1@1239|Firmicutes	1239|Firmicutes	L	COG1112 Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,zf-C4_Topoisom
SRR25158343_k127_982352_63	472759.Nhal_3830	6.227e-14	74.0	COG5304@1|root,COG5304@2|Bacteria,1NBCZ@1224|Proteobacteria,1SCSH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
SRR25158343_k127_982352_45	1499967.BAYZ01000104_gene3668	3.093e-29	119.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR25158343_k127_982352_71	292563.Cyast_0003	1.886e-07	55.0	COG3041@1|root,COG3041@2|Bacteria,1G76D@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM Addiction module toxin, RelE StbE	-	-	-	-	-	-	-	-	-	-	-	-	YafQ_toxin
SRR25158343_k127_982352_61	1223410.KN050846_gene2586	4.884e-15	78.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,1HXTK@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158343_k127_98898_0	697281.Mahau_2167	3.925e-43	161.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158343_k127_98898_2	981384.AEYW01000025_gene4166	7.932e-06	56.0	COG1051@1|root,COG1051@2|Bacteria,1N1KH@1224|Proteobacteria,2UA1K@28211|Alphaproteobacteria,4NCCF@97050|Ruegeria	28211|Alphaproteobacteria	F	Belongs to the Nudix hydrolase family	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_98898_1	28072.Nos7524_0473	6.387e-07	59.0	COG1476@1|root,COG1476@2|Bacteria,1G7B8@1117|Cyanobacteria	1117|Cyanobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
## 1046 queries scanned
## Total time (seconds): 16.829107522964478
## Rate: 62.15 q/s