## Sun Dec 14 09:30:18 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158343_bin.5.fa -m mmseqs --itype genome -o SRR25158343_bin.5 --output_dir /data/result/bins/wyx/egg/SRR25158343_bin.5 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158343_k127_113052_0	272134.KB731325_gene782	2.804e-69	237.0	COG1943@1|root,COG1943@2|Bacteria,1G603@1117|Cyanobacteria,1HC8N@1150|Oscillatoriales	1117|Cyanobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158343_k127_113052_1	1121091.AUMP01000006_gene4215	2.637e-32	131.0	COG2318@1|root,COG2318@2|Bacteria,1VC1G@1239|Firmicutes,4HMPJ@91061|Bacilli	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1191054_1	1122176.KB903565_gene3327	1.248e-188	603.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,4NK7Y@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
SRR25158343_k127_1191054_0	1237149.C900_05550	4.578e-286	897.0	COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRR25158343_k127_1191054_2	1242864.D187_008887	2.708e-147	484.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,EF-hand_5,Metallophos
SRR25158343_k127_1191054_3	1122138.AQUZ01000032_gene7197	1.058e-63	227.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4DN3M@85009|Propionibacteriales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158343_k127_1298059_1	143224.JQMD01000002_gene401	4.177e-38	149.0	COG2808@1|root,COG2808@2|Bacteria,4NINW@976|Bacteroidetes,1HZF0@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158343_k127_1298059_0	272134.KB731328_gene835	1.379e-107	357.0	COG3039@1|root,COG3039@2|Bacteria,1G7AF@1117|Cyanobacteria,1HFJI@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_5
SRR25158343_k127_1298059_2	1122604.JONR01000031_gene1290	8.817e-25	109.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,1X3F8@135614|Xanthomonadales	135614|Xanthomonadales	E	aminopeptidase	pepN	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158343_k127_1436692_23	234267.Acid_3868	2.786e-08	55.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158343_k127_1436692_0	1172185.KB911509_gene350	5.081e-223	715.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4FVKA@85025|Nocardiaceae	201174|Actinobacteria	O	HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158343_k127_1436692_18	1123320.KB889691_gene334	3.386e-28	116.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria	201174|Actinobacteria	O	Hydrogenase expression formation protein	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158343_k127_1436692_1	1521187.JPIM01000002_gene3139	1.665e-191	602.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,376PX@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158343_k127_1436692_19	485913.Krac_2530	2.553e-21	99.0	2DSXJ@1|root,33HU5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1436692_6	926550.CLDAP_24400	3.419e-147	473.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158343_k127_1436692_4	1340493.JNIF01000003_gene3161	1.835e-162	551.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_1436692_24	665571.STHERM_c06610	4.083e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,2J5PC@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158343_k127_1436692_9	649349.Lbys_1863	4.821e-79	277.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158343_k127_1436692_20	946362.XP_004987456.1	9.043e-20	99.0	COG0457@1|root,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	-	-	-	-	-	-	-	-	-	PH,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
SRR25158343_k127_1436692_16	1278073.MYSTI_01802	2.196e-33	149.0	2DEWU@1|root,2ZPJP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1436692_22	471854.Dfer_3481	8.373e-14	85.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158343_k127_1436692_11	865937.Gilli_0793	8.155e-74	276.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1IH9T@117743|Flavobacteriia,2P7KS@244698|Gillisia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158343_k127_1436692_17	391603.FBALC1_14282	2.325e-28	128.0	2EHYH@1|root,33BPY@2|Bacteria,4NZPB@976|Bacteroidetes,1I6BP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1436692_2	234267.Acid_5342	1.621e-171	546.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053,ko:K13735	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05100,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map05100	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	NHL,SGL
SRR25158343_k127_1436692_21	1122603.ATVI01000005_gene2979	1.167e-15	82.0	COG2159@1|root,COG2159@2|Bacteria,1QDV1@1224|Proteobacteria,1RYCT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158343_k127_1436692_14	1121007.AUML01000001_gene1306	1.551e-45	177.0	COG1506@1|root,COG1506@2|Bacteria,4NKM9@976|Bacteroidetes,1I0MY@117743|Flavobacteriia,2YKM2@290174|Aquimarina	976|Bacteroidetes	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158343_k127_1436692_7	204669.Acid345_0069	5.493e-106	357.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158343_k127_1436692_12	1408473.JHXO01000009_gene3383	4.778e-68	252.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,2FMQC@200643|Bacteroidia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158343_k127_1436692_13	204669.Acid345_1709	1.861e-47	184.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158343_k127_1436692_15	743719.PaelaDRAFT_0670	4.749e-36	142.0	COG0454@1|root,COG0454@2|Bacteria,1V2V3@1239|Firmicutes,4HMUS@91061|Bacilli,26YSY@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR25158343_k127_1436692_5	661478.OP10G_2288	7.926e-157	512.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
SRR25158343_k127_1436692_8	1122604.JONR01000033_gene34	8.268e-81	276.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158343_k127_1436692_10	1254432.SCE1572_26545	6.644e-75	265.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158343_k127_1436692_3	204669.Acid345_2229	1.549e-166	549.0	COG0308@1|root,COG0308@2|Bacteria,3Y7E9@57723|Acidobacteria,2JMED@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_1488559_1	1385517.N800_12010	2.272e-15	77.0	2AQ2A@1|root,31F7E@2|Bacteria,1QCMG@1224|Proteobacteria,1T8CS@1236|Gammaproteobacteria,1XAFU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1488559_0	1121918.ARWE01000001_gene1736	3.304e-164	526.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42PR5@68525|delta/epsilon subdivisions,2WMGT@28221|Deltaproteobacteria,43W24@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158343_k127_15162_2	1382356.JQMP01000001_gene1111	2.317e-45	177.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G64X@200795|Chloroflexi,27Z3R@189775|Thermomicrobia	189775|Thermomicrobia	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,GGDEF,NB-ARC,TPR_12
SRR25158343_k127_15162_3	980584.AFPB01000138_gene2690	2.47e-26	117.0	2C0A3@1|root,32Y9P@2|Bacteria,4PPZ1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_15162_0	290315.Clim_0035	0.0	1475.0	COG0243@1|root,COG0243@2|Bacteria,1FDP0@1090|Chlorobi	1090|Chlorobi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158343_k127_15162_4	237368.SCABRO_00288	4.188e-19	89.0	2DNV7@1|root,32ZAW@2|Bacteria,2J4XF@203682|Planctomycetes	203682|Planctomycetes	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158343_k127_15162_5	926561.KB900617_gene2071	0.0001037	48.0	COG0614@1|root,COG0614@2|Bacteria,1VDHT@1239|Firmicutes	1239|Firmicutes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158343_k127_15162_1	1122176.KB903565_gene3327	4.674e-71	249.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,4NK7Y@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
SRR25158343_k127_1546895_221	1121918.ARWE01000001_gene1836	3.394e-06	49.0	COG4968@1|root,COG4968@2|Bacteria,1QXNR@1224|Proteobacteria,43C4N@68525|delta/epsilon subdivisions,2WRDZ@28221|Deltaproteobacteria,43VE1@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA-N	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
SRR25158343_k127_1546895_36	1047013.AQSP01000115_gene361	5.269e-133	438.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1546895_89	330214.NIDE0778	1.54e-77	281.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158343_k127_1546895_162	572546.Arcpr_1022	2.46e-36	140.0	COG0836@1|root,arCOG02427@2157|Archaea,2XUHF@28890|Euryarchaeota,245ZJ@183980|Archaeoglobi	183980|Archaeoglobi	M	mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158343_k127_1546895_114	269799.Gmet_2345	2.661e-59	218.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158343_k127_1546895_185	1187851.A33M_2147	4.197e-23	109.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	epimerase dehydratase	rfbE	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158343_k127_1546895_136	56780.SYN_01954	2.732e-48	186.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
SRR25158343_k127_1546895_105	56780.SYN_01953	1.542e-67	235.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_1546895_97	880072.Desac_2808	2.847e-74	262.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2MRAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158343_k127_1546895_41	1198114.AciX9_1130	2.372e-129	447.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158343_k127_1546895_2	489825.LYNGBM3L_04500	4.13e-310	964.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158343_k127_1546895_45	41431.PCC8801_0820	1.691e-123	423.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGV5@43988|Cyanothece	1117|Cyanobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,Response_reg
SRR25158343_k127_1546895_30	555079.Toce_1130	6.648e-144	466.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158343_k127_1546895_148	1122921.KB898201_gene3195	1.007e-38	160.0	COG0535@1|root,COG0535@2|Bacteria,1UXWS@1239|Firmicutes	1239|Firmicutes	C	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158343_k127_1546895_154	497964.CfE428DRAFT_2498	7.032e-38	157.0	COG0707@1|root,COG0707@2|Bacteria,46SRU@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
SRR25158343_k127_1546895_123	215803.DB30_4430	1.876e-53	197.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YV5Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.304,1.1.1.47,1.1.1.76	ko:K00034,ko:K03366	ko00030,ko00650,ko01120,ko01200,map00030,map00650,map01120,map01200	-	R01520,R01521,R02855,R02946,R03707,R09078,R10505	RC00066,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158343_k127_1546895_172	575540.Isop_1303	2.381e-28	119.0	COG2193@1|root,COG2193@2|Bacteria,2IZYI@203682|Planctomycetes	203682|Planctomycetes	P	COG2193 Bacterioferritin (cytochrome b1)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158343_k127_1546895_132	234267.Acid_4617	5.527e-50	190.0	COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
SRR25158343_k127_1546895_19	309807.SRU_2648	2.039e-168	570.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1FIRV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
SRR25158343_k127_1546895_125	391625.PPSIR1_35862	5.818e-53	205.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158343_k127_1546895_71	768670.Calni_1865	2.08e-94	342.0	COG1391@1|root,COG1391@2|Bacteria,2GEZ7@200930|Deferribacteres	200930|Deferribacteres	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158343_k127_1546895_53	518766.Rmar_0925	2.267e-117	400.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158343_k127_1546895_56	344747.PM8797T_07337	2.985e-115	389.0	COG0591@1|root,COG0591@2|Bacteria,2IXNM@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158343_k127_1546895_74	1340493.JNIF01000003_gene1659	7.966e-90	304.0	COG2103@1|root,COG2103@2|Bacteria,3Y378@57723|Acidobacteria	57723|Acidobacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS_2
SRR25158343_k127_1546895_168	1293054.HSACCH_02396	8.379e-34	144.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,24BFK@186801|Clostridia	186801|Clostridia	G	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158343_k127_1546895_155	2340.JV46_22820	1.029e-37	153.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RQJD@1236|Gammaproteobacteria,1J60A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	LysR substrate binding domain	rbcR	-	-	ko:K21703,ko:K21711	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158343_k127_1546895_7	344747.PM8797T_07137	4.3e-248	792.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes	203682|Planctomycetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
SRR25158343_k127_1546895_26	682795.AciX8_2265	6.563e-151	520.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158343_k127_1546895_198	234267.Acid_2108	2.528e-18	96.0	COG0457@1|root,COG0457@2|Bacteria,3Y4E6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_1546895_98	515635.Dtur_0223	2.268e-72	258.0	COG1820@1|root,COG1820@2|Bacteria	2|Bacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158343_k127_1546895_187	760192.Halhy_6170	2.992e-22	107.0	2BF41@1|root,328W8@2|Bacteria,4P6H7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_131	313606.M23134_05224	5.179e-50	189.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158343_k127_1546895_58	1121930.AQXG01000001_gene1215	6.77e-112	377.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158343_k127_1546895_44	1123366.TH3_06160	2.323e-124	406.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,2JPRA@204441|Rhodospirillales	204441|Rhodospirillales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
SRR25158343_k127_1546895_59	671143.DAMO_1598	2.529e-107	359.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158343_k127_1546895_28	278963.ATWD01000001_gene2473	8.419e-146	485.0	COG4232@1|root,COG4232@2|Bacteria,3Y771@57723|Acidobacteria	57723|Acidobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD,Thioredoxin_7
SRR25158343_k127_1546895_159	204669.Acid345_2687	5.484e-37	147.0	COG5553@1|root,COG5553@2|Bacteria,3Y975@57723|Acidobacteria,2JNQM@204432|Acidobacteriia	204432|Acidobacteriia	S	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
SRR25158343_k127_1546895_212	1123013.AUIC01000003_gene346	1.291e-11	77.0	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria,4FKGE@85023|Microbacteriaceae	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158343_k127_1546895_34	759914.BP951000_1063	2.076e-138	454.0	COG0215@1|root,COG0215@2|Bacteria,2J618@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158343_k127_1546895_13	502025.Hoch_1577	1.685e-201	661.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_1546895_121	234267.Acid_1209	8.768e-55	198.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_1546895_146	620914.JH621256_gene1202	1.806e-39	152.0	COG1017@1|root,COG1017@2|Bacteria,4NS54@976|Bacteroidetes,1I7HW@117743|Flavobacteriia,2YKVA@290174|Aquimarina	976|Bacteroidetes	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	Globin
SRR25158343_k127_1546895_226	1210884.HG799462_gene8690	5.047e-05	47.0	COG2165@1|root,COG2165@2|Bacteria,2J0D5@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
SRR25158343_k127_1546895_191	1296416.JACB01000015_gene4681	4.459e-21	107.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_1546895_188	32057.KB217478_gene4556	4.984e-22	101.0	2CKCH@1|root,331PP@2|Bacteria,1G6N7@1117|Cyanobacteria,1HSVM@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_106	435908.IDSA_06045	1.771e-67	236.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Bacterioferritin	IV02_12050	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158343_k127_1546895_167	525904.Tter_0978	6.346e-34	137.0	COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria	2|Bacteria	L	HNH endonuclease	MA20_20605	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158343_k127_1546895_178	672.VV93_v1c00560	3.818e-26	113.0	COG0739@1|root,COG0739@2|Bacteria,1NF7B@1224|Proteobacteria	1224|Proteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR25158343_k127_1546895_157	980584.AFPB01000138_gene2681	1.54e-37	145.0	COG1017@1|root,COG1017@2|Bacteria,4PK8Z@976|Bacteroidetes,1IEWB@117743|Flavobacteriia,40777@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	Globin
SRR25158343_k127_1546895_22	1209072.ALBT01000017_gene4194	1.006e-154	492.0	COG0657@1|root,COG0657@2|Bacteria,1R79Q@1224|Proteobacteria,1S1MN@1236|Gammaproteobacteria,1FI3R@10|Cellvibrio	1236|Gammaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158343_k127_1546895_117	1341181.FLJC2902T_31630	1.051e-56	207.0	28JZ4@1|root,2Z90G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_176	1347342.BN863_18080	2.222e-26	119.0	2CIMC@1|root,32UX7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_20	118168.MC7420_1072	1.039e-162	520.0	COG1690@1|root,COG1690@2|Bacteria,1G0YE@1117|Cyanobacteria,1H8KT@1150|Oscillatoriales	1117|Cyanobacteria	S	family UPF0027	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,RtcB
SRR25158343_k127_1546895_78	1379698.RBG1_1C00001G1080	7.025e-87	317.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158343_k127_1546895_210	710686.Mycsm_02852	3.614e-13	77.0	COG0454@1|root,COG0456@2|Bacteria,2HHH0@201174|Actinobacteria,239YV@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_1546895_153	1458357.BG58_05000	5.266e-38	155.0	2CDZ6@1|root,2Z8WW@2|Bacteria,1R8IP@1224|Proteobacteria,2W7PR@28216|Betaproteobacteria,1KEXM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SRR25158343_k127_1546895_12	497964.CfE428DRAFT_5214	6.387e-204	647.0	COG2425@1|root,COG2425@2|Bacteria,46UN1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TROVE domain	-	-	-	-	-	-	-	-	-	-	-	-	TROVE
SRR25158343_k127_1546895_67	395961.Cyan7425_0002	2.012e-96	325.0	COG0300@1|root,COG0300@2|Bacteria,1G2Y4@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_1546895_32	756499.Desde_1179	2.648e-143	469.0	COG0318@1|root,COG0318@2|Bacteria,1TQKH@1239|Firmicutes,24ZPR@186801|Clostridia,26479@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158343_k127_1546895_116	504472.Slin_5367	1.129e-57	202.0	COG4270@1|root,COG4270@2|Bacteria,4NQEX@976|Bacteroidetes,47RC1@768503|Cytophagia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_233	1183438.GKIL_2486	0.0009726	42.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_109	1131269.AQVV01000007_gene1072	2.562e-63	229.0	COG0611@1|root,COG0611@2|Bacteria	2|Bacteria	H	thiamine-phosphate kinase activity	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946,ko:K07123	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c,iSFV_1184.SFV_0382,iYO844.BSU05900	AIRS,AIRS_C
SRR25158343_k127_1546895_179	234267.Acid_0018	8.645e-26	113.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158343_k127_1546895_31	234267.Acid_5786	2.257e-143	469.0	COG0265@1|root,COG0265@2|Bacteria,3Y2WB@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_1546895_118	502025.Hoch_4959	2.038e-55	214.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4399Y@68525|delta/epsilon subdivisions,2X4HE@28221|Deltaproteobacteria,2YZ0V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase; unclassified specificity.	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_1546895_65	886293.Sinac_0554	6.307e-98	334.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,2J2EJ@203682|Planctomycetes	203682|Planctomycetes	KLT	Forkhead associated domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
SRR25158343_k127_1546895_101	1382356.JQMP01000004_gene670	1.304e-70	246.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1546895_232	1120958.AULD01000006_gene554	0.0005676	52.0	COG3307@1|root,COG3307@2|Bacteria,2HBS3@201174|Actinobacteria,4FM8P@85023|Microbacteriaceae	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158343_k127_1546895_122	29581.BW37_01012	1.705e-54	204.0	2DVR0@1|root,33WUQ@2|Bacteria,1N2BP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_54	234267.Acid_1598	3.892e-116	383.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158343_k127_1546895_129	682795.AciX8_3099	3.798e-50	193.0	COG1295@1|root,COG1295@2|Bacteria,3Y3RZ@57723|Acidobacteria,2JIYV@204432|Acidobacteriia	204432|Acidobacteriia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158343_k127_1546895_47	945713.IALB_0983	3.867e-122	402.0	COG4299@1|root,COG4299@2|Bacteria	2|Bacteria	G	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
SRR25158343_k127_1546895_50	204669.Acid345_2300	7.148e-119	408.0	COG5316@1|root,COG5316@2|Bacteria,3Y46P@57723|Acidobacteria,2JMJ4@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SRR25158343_k127_1546895_147	935948.KE386494_gene986	9.132e-39	154.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,42G4W@68295|Thermoanaerobacterales	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158343_k127_1546895_194	333138.LQ50_14255	1.082e-19	101.0	COG3153@1|root,COG3153@2|Bacteria,1V0I4@1239|Firmicutes,4HCMH@91061|Bacilli,1ZJWG@1386|Bacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SRR25158343_k127_1546895_10	204669.Acid345_0047	2.854e-216	697.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria,2JIDH@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158343_k127_1546895_144	1519464.HY22_03120	5.269e-41	157.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158343_k127_1546895_171	1121920.AUAU01000009_gene1864	4.981e-31	142.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_180	234267.Acid_5658	1.466e-25	123.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_21	1379270.AUXF01000002_gene1516	2.139e-156	509.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158343_k127_1546895_81	1191523.MROS_0140	9.463e-85	299.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158343_k127_1546895_73	1267534.KB906757_gene1004	5.683e-91	310.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158343_k127_1546895_213	639030.JHVA01000001_gene2861	1.25e-10	71.0	2C0ZI@1|root,2ZAKK@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
SRR25158343_k127_1546895_23	234267.Acid_7221	1.152e-153	497.0	COG2271@1|root,COG2271@2|Bacteria,3Y2VG@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
SRR25158343_k127_1546895_108	639030.JHVA01000001_gene600	1.975e-64	229.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria,2JI6U@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158343_k127_1546895_86	234267.Acid_2975	1.473e-79	285.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_1546895_9	1267534.KB906757_gene1007	3.622e-223	709.0	2C0ZI@1|root,2ZAKK@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
SRR25158343_k127_1546895_220	1385511.N783_00010	1.945e-06	55.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli	91061|Bacilli	CG	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
SRR25158343_k127_1546895_35	247490.KSU1_C1276	1.881e-135	445.0	COG1012@1|root,COG1012@2|Bacteria,2IXMZ@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158343_k127_1546895_38	204669.Acid345_1052	2.599e-132	455.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_1546895_138	1267535.KB906767_gene4499	6.349e-48	178.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_1546895_209	317936.Nos7107_1718	2.197e-13	78.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_1546895_201	1198114.AciX9_2169	1.223e-16	88.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_1546895_217	582515.KR51_00021740	4.095e-09	65.0	296NU@1|root,2ZTXX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_231	525244.HMPREF0023_1514	0.0002962	49.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,3NK23@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158343_k127_1546895_208	643473.KB235930_gene2545	3.529e-14	83.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_1546895_5	1128421.JAGA01000004_gene2674	3.257e-268	834.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158343_k127_1546895_15	572546.Arcpr_1593	2.724e-184	601.0	COG0380@1|root,arCOG02831@2157|Archaea,2XSTE@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0380 Trehalose-6-phosphate synthase	otsA	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158343_k127_1546895_33	1117108.PAALTS15_15956	1.633e-141	478.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26SSP@186822|Paenibacillaceae	91061|Bacilli	S	Penicillin amidase	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158343_k127_1546895_193	685035.ADAE01000018_gene863	8.967e-20	96.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2K4GA@204457|Sphingomonadales	204457|Sphingomonadales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158343_k127_1546895_104	204669.Acid345_4232	3.044e-69	251.0	COG0793@1|root,COG0793@2|Bacteria,3Y3A7@57723|Acidobacteria,2JHJK@204432|Acidobacteriia	204432|Acidobacteriia	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158343_k127_1546895_145	886293.Sinac_6048	1.259e-39	153.0	COG0454@1|root,COG0454@2|Bacteria,2J01A@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
SRR25158343_k127_1546895_62	643473.KB235930_gene4348	2.089e-102	349.0	COG2124@1|root,COG2124@2|Bacteria,1G3SX@1117|Cyanobacteria,1HMP2@1161|Nostocales	1117|Cyanobacteria	Q	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158343_k127_1546895_137	204669.Acid345_0749	4.44e-48	192.0	COG0755@1|root,COG0755@2|Bacteria,3Y3QF@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158343_k127_1546895_164	443144.GM21_3520	5.743e-36	154.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,43SZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158343_k127_1546895_93	1267535.KB906767_gene1277	1.344e-76	267.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158343_k127_1546895_197	204669.Acid345_0439	2.114e-19	97.0	COG1845@1|root,COG1845@2|Bacteria,3Y2KJ@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158343_k127_1546895_170	313595.P700755_002189	3e-33	133.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia,4C39E@83612|Psychroflexus	976|Bacteroidetes	S	Protein of unknown function (DUF420)	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SRR25158343_k127_1546895_46	1379698.RBG1_1C00001G0798	2.766e-123	419.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
SRR25158343_k127_1546895_69	1267534.KB906754_gene2801	1.811e-94	331.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158343_k127_1546895_49	479437.Elen_1221	4.098e-120	394.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CV2B@84998|Coriobacteriia	84998|Coriobacteriia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158343_k127_1546895_128	1173026.Glo7428_2246	4.843e-52	189.0	COG1670@1|root,COG1670@2|Bacteria,1G5HU@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158343_k127_1546895_40	1121382.JQKG01000006_gene3411	8.603e-130	422.0	COG4608@1|root,COG4608@2|Bacteria,1WI6F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158343_k127_1546895_196	234267.Acid_1121	1.94e-19	98.0	2BRBT@1|root,32KAC@2|Bacteria,3Y4U0@57723|Acidobacteria	57723|Acidobacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158343_k127_1546895_68	204669.Acid345_4376	1.159e-95	327.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria,2JMFF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1546895_82	1340493.JNIF01000003_gene4681	1.024e-84	295.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1546895_113	925409.KI911562_gene2682	2.582e-61	218.0	29R44@1|root,30C5C@2|Bacteria,4NN15@976|Bacteroidetes,1ISDR@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_63	682795.AciX8_1569	2.467e-102	338.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1546895_120	204669.Acid345_3323	7.704e-55	212.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XR@57723|Acidobacteria,2JHTV@204432|Acidobacteriia	204432|Acidobacteriia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158343_k127_1546895_195	196162.Noca_2713	1.289e-19	96.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DR1A@85009|Propionibacteriales	201174|Actinobacteria	T	zinc-ribbon domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158343_k127_1546895_115	867845.KI911784_gene3628	6.448e-58	228.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi,375D7@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
SRR25158343_k127_1546895_215	1051501.AYTL01000034_gene3342	2.353e-09	65.0	COG1714@1|root,COG1714@2|Bacteria,1V6N5@1239|Firmicutes,4HJRB@91061|Bacilli,1ZI28@1386|Bacillus	91061|Bacilli	S	membrane	yckC	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158343_k127_1546895_79	234267.Acid_3432	1.728e-85	306.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
SRR25158343_k127_1546895_183	926566.Terro_2784	1.593e-23	104.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158343_k127_1546895_229	684949.ATTJ01000001_gene1517	0.0001697	46.0	COG0387@1|root,COG0387@2|Bacteria,1WJIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158343_k127_1546895_143	768671.ThimaDRAFT_1683	1.348e-41	158.0	COG4828@1|root,COG4828@2|Bacteria,1NPF1@1224|Proteobacteria,1SH6F@1236|Gammaproteobacteria,1X1YB@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR25158343_k127_1546895_51	1121324.CLIT_4c00250	1.342e-118	404.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,25RVB@186804|Peptostreptococcaceae	186801|Clostridia	P	CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158343_k127_1546895_95	247490.KSU1_C0634	1.634e-74	264.0	COG0628@1|root,COG0628@2|Bacteria,2J2TA@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158343_k127_1546895_57	1185876.BN8_05235	5.89e-113	372.0	COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,47PYQ@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
SRR25158343_k127_1546895_48	1356852.N008_20660	8.457e-122	404.0	COG4325@1|root,COG4325@2|Bacteria,4NFB6@976|Bacteroidetes,47N5E@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158343_k127_1546895_29	28072.Nos7524_2709	3.108e-145	481.0	COG1808@1|root,COG1808@2|Bacteria,1G3Y7@1117|Cyanobacteria,1HJ64@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158343_k127_1546895_135	489825.LYNGBM3L_16280	5.925e-49	183.0	COG2197@1|root,COG2197@2|Bacteria,1G0N8@1117|Cyanobacteria,1H7M9@1150|Oscillatoriales	1117|Cyanobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_1546895_151	575540.Isop_1850	1.918e-38	164.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
SRR25158343_k127_1546895_156	998674.ATTE01000001_gene1643	1.392e-37	147.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1S65I@1236|Gammaproteobacteria,462YF@72273|Thiotrichales	72273|Thiotrichales	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	MgtC
SRR25158343_k127_1546895_152	1267535.KB906767_gene635	2.15e-38	156.0	COG2968@1|root,COG2968@2|Bacteria,3Y844@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158343_k127_1546895_206	1232428.CAVO010000025_gene1625	1.027e-14	87.0	COG1376@1|root,COG1376@2|Bacteria,1TQAB@1239|Firmicutes,4H267@909932|Negativicutes	909932|Negativicutes	S	ErfK YbiS YcfS YnhG	erfK	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,YkuD
SRR25158343_k127_1546895_126	1307437.J139_04670	8.182e-53	191.0	COG2323@1|root,COG2323@2|Bacteria,1MW5I@1224|Proteobacteria,1S44G@1236|Gammaproteobacteria,2Q0T2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158343_k127_1546895_124	761193.Runsl_2645	5.603e-53	193.0	2DIFQ@1|root,30348@2|Bacteria,4NNAK@976|Bacteroidetes,47PM1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_0	153721.MYP_2694	0.0	1078.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,47KDS@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158343_k127_1546895_150	1476583.DEIPH_ctg139orf0014	1.676e-38	154.0	COG0517@1|root,COG0517@2|Bacteria,1WNHR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158343_k127_1546895_75	357808.RoseRS_1529	7.958e-89	312.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_1546895_107	1267534.KB906760_gene1549	1.431e-65	255.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158343_k127_1546895_18	1239962.C943_04413	5.299e-169	536.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158343_k127_1546895_199	1469607.KK073769_gene5664	3.01e-17	87.0	COG5499@1|root,COG5499@2|Bacteria,1G6YN@1117|Cyanobacteria,1HNWU@1161|Nostocales	1117|Cyanobacteria	K	COGs COG5499 transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
SRR25158343_k127_1546895_181	1210884.HG799463_gene10329	3.748e-24	104.0	COG4680@1|root,COG4680@2|Bacteria,2J3QG@203682|Planctomycetes	203682|Planctomycetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
SRR25158343_k127_1546895_4	1288963.ADIS_2622	2.585e-283	880.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,47KM5@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
SRR25158343_k127_1546895_166	616991.JPOO01000003_gene1429	1.966e-35	138.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1I3II@117743|Flavobacteriia,23IG9@178469|Arenibacter	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158343_k127_1546895_1	1121904.ARBP01000004_gene790	1.4e-322	994.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,4NG9R@976|Bacteroidetes,47KDW@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
SRR25158343_k127_1546895_94	204669.Acid345_1988	1.914e-76	276.0	COG0747@1|root,COG0747@2|Bacteria,3Y44K@57723|Acidobacteria,2JHM9@204432|Acidobacteriia	204432|Acidobacteriia	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158343_k127_1546895_103	1403819.BATR01000162_gene5300	1.413e-69	250.0	COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,2ITMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158343_k127_1546895_6	234267.Acid_4760	7.448e-252	805.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158343_k127_1546895_141	161156.JQKW01000011_gene955	4.277e-42	167.0	COG0388@1|root,COG0615@1|root,COG0388@2|Bacteria,COG0615@2|Bacteria,2GHDJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,CTP_transf_like
SRR25158343_k127_1546895_90	572544.Ilyop_1819	2.136e-77	269.0	COG2870@1|root,COG2870@2|Bacteria,378KV@32066|Fusobacteria	32066|Fusobacteria	M	Psort location Cytoplasmic, score	rfaE1	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158343_k127_1546895_174	1198114.AciX9_2167	2.951e-27	122.0	COG0463@1|root,COG0463@2|Bacteria,3Y8M0@57723|Acidobacteria,2JNIR@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_219	111781.Lepto7376_3465	7.557e-07	60.0	COG1216@1|root,COG1216@2|Bacteria,1GQRT@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase (GlcNAc)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc,NTP_transf_5
SRR25158343_k127_1546895_200	86106.I862_00955	4.101e-17	91.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,47FPG@766|Rickettsiales	766|Rickettsiales	O	COG1214 Inactive homolog of metal-dependent proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
SRR25158343_k127_1546895_230	1235803.C825_01817	0.0002019	53.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NI0T@976|Bacteroidetes,2G2NV@200643|Bacteroidia,22ZNR@171551|Porphyromonadaceae	976|Bacteroidetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosN,PQQ_2,PQQ_3
SRR25158343_k127_1546895_160	1201290.M902_0516	6.005e-37	143.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2MT2P@213481|Bdellovibrionales,2WNAN@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158343_k127_1546895_64	234267.Acid_7935	5.643e-98	327.0	COG0825@1|root,COG0825@2|Bacteria,3Y34D@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158343_k127_1546895_3	1158318.ATXC01000002_gene1498	4.297e-295	944.0	COG0587@1|root,COG0587@2|Bacteria,2G3PZ@200783|Aquificae	200783|Aquificae	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
SRR25158343_k127_1546895_60	246194.CHY_1398	4.583e-107	362.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,42FC8@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158343_k127_1546895_142	1267533.KB906738_gene2151	1.01e-41	158.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria,2JJ7J@204432|Acidobacteriia	204432|Acidobacteriia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158343_k127_1546895_87	1047013.AQSP01000134_gene1378	1.528e-79	272.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158343_k127_1546895_112	1047013.AQSP01000134_gene1379	2.11e-61	221.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158343_k127_1546895_17	1267535.KB906767_gene3229	3.859e-177	563.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158343_k127_1546895_14	306281.AJLK01000150_gene1926	3.541e-200	630.0	COG0499@1|root,COG0499@2|Bacteria,1G1MN@1117|Cyanobacteria,1JJ5C@1189|Stigonemataceae	1117|Cyanobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158343_k127_1546895_140	204669.Acid345_1515	7.027e-45	186.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
SRR25158343_k127_1546895_182	1267535.KB906767_gene1892	9.891e-24	111.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria,2JJ0T@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158343_k127_1546895_207	1047013.AQSP01000086_gene2015	3.236e-14	77.0	2B6R1@1|root,31ZPU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_43	1178540.BA70_14680	1.851e-126	415.0	COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1ZBF3@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ybbC	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158343_k127_1546895_139	1499967.BAYZ01000172_gene5769	2.98e-46	175.0	COG2071@1|root,COG2071@2|Bacteria,2NPQK@2323|unclassified Bacteria	2|Bacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158343_k127_1546895_102	1382359.JIAL01000001_gene1358	2.658e-70	242.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158343_k127_1546895_16	234267.Acid_7339	2.113e-179	572.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria	57723|Acidobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158343_k127_1546895_211	439481.Aboo_0327	8.185e-13	80.0	COG4934@1|root,arCOG05978@1|root,arCOG03669@2157|Archaea,arCOG05978@2157|Archaea,2Y7X2@28890|Euryarchaeota,3F38G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ,fn3
SRR25158343_k127_1546895_91	717231.Flexsi_1969	2.299e-77	266.0	COG0179@1|root,COG0179@2|Bacteria,2GF3S@200930|Deferribacteres	200930|Deferribacteres	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158343_k127_1546895_77	656519.Halsa_0675	1.241e-87	294.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3WABK@53433|Halanaerobiales	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158343_k127_1546895_84	1306174.JODP01000016_gene7221	3.478e-81	279.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158343_k127_1546895_189	1086011.HJ01_03285	1.089e-21	100.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_1546895_134	1157640.AQWO01000010_gene2827	7.298e-50	186.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158343_k127_1546895_204	1122915.AUGY01000110_gene6805	4.326e-16	84.0	COG3557@1|root,COG3557@2|Bacteria,1VC3B@1239|Firmicutes,4HM4G@91061|Bacilli,26XZF@186822|Paenibacillaceae	91061|Bacilli	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
SRR25158343_k127_1546895_163	289376.THEYE_A1249	2.779e-36	147.0	COG0842@1|root,COG0842@2|Bacteria,3J170@40117|Nitrospirae	40117|Nitrospirae	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K09694	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane
SRR25158343_k127_1546895_8	204669.Acid345_4697	2.77e-243	760.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158343_k127_1546895_227	706587.Desti_0054	8.979e-05	50.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MS60@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158343_k127_1546895_80	671143.DAMO_0342	5.699e-85	288.0	COG0149@1|root,COG0149@2|Bacteria,2NP24@2323|unclassified Bacteria	2|Bacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4715	TIM
SRR25158343_k127_1546895_42	390874.Tpet_0242	9.348e-129	425.0	COG0126@1|root,COG0126@2|Bacteria,2GBXW@200918|Thermotogae	200918|Thermotogae	F	belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK,TIM
SRR25158343_k127_1546895_205	545243.BAEV01000002_gene3299	7.994e-16	87.0	2DMIQ@1|root,32RV1@2|Bacteria,1VGN9@1239|Firmicutes,24I6Q@186801|Clostridia,36J8N@31979|Clostridiaceae	186801|Clostridia	S	Domain of Unknown Function with PDB structure (DUF3862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3862
SRR25158343_k127_1546895_24	204669.Acid345_2541	1.612e-151	484.0	COG0057@1|root,COG0057@2|Bacteria,3Y2QC@57723|Acidobacteria,2JI8H@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158343_k127_1546895_216	521674.Plim_0090	3.47e-09	70.0	COG1538@1|root,COG1538@2|Bacteria,2IYRU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158343_k127_1546895_110	247490.KSU1_D0287	4.919e-63	226.0	COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1546895_161	234267.Acid_6308	8.459e-37	150.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_1546895_55	1382306.JNIM01000001_gene3774	1.928e-115	383.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158343_k127_1546895_83	1267533.KB906734_gene4271	1.06e-81	283.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158343_k127_1546895_190	1121935.AQXX01000136_gene4070	2.643e-21	96.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XKZ0@135619|Oceanospirillales	135619|Oceanospirillales	G	Phosphocarrier protein HPr	ptsO	-	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
SRR25158343_k127_1546895_169	1499967.BAYZ01000065_gene6106	1.893e-33	134.0	COG2893@1|root,COG2893@2|Bacteria,2NRCX@2323|unclassified Bacteria	2|Bacteria	G	PTS system fructose IIA component	manX	-	2.7.1.191,2.7.1.194	ko:K02793,ko:K02794,ko:K02821	ko00051,ko00053,ko00520,ko01100,ko01120,ko02060,map00051,map00053,map00520,map01100,map01120,map02060	M00276,M00283,M00550	R02630,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.7.1	-	-	EIIA-man
SRR25158343_k127_1546895_96	1382359.JIAL01000001_gene2585	1.858e-74	261.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria,2JHJM@204432|Acidobacteriia	204432|Acidobacteriia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158343_k127_1546895_88	1304888.ATWF01000001_gene682	1.428e-78	273.0	COG1493@1|root,COG1493@2|Bacteria,2GF33@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
SRR25158343_k127_1546895_173	592026.GCWU0000282_001589	2.428e-28	121.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158343_k127_1546895_66	1382359.JIAL01000001_gene2583	3.906e-97	337.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria,2JIY6@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158343_k127_1546895_72	288000.BBta_0122	7.585e-92	309.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,3JSM6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158343_k127_1546895_177	204669.Acid345_1660	2.591e-26	127.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
SRR25158343_k127_1546895_27	204669.Acid345_4172	5.389e-146	481.0	COG0608@1|root,COG0608@2|Bacteria,3Y3HI@57723|Acidobacteria,2JICS@204432|Acidobacteriia	204432|Acidobacteriia	L	single-stranded-DNA-specific exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_1546895_92	335543.Sfum_0725	1.096e-76	266.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MRXH@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158343_k127_1546895_133	469610.HMPREF0189_00071	6.203e-50	187.0	COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,2VIWD@28216|Betaproteobacteria,1KJX2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	wcbP	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_1546895_202	555088.DealDRAFT_3051	2.712e-16	84.0	COG3603@1|root,COG3603@2|Bacteria	2|Bacteria	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
SRR25158343_k127_1546895_25	1121472.AQWN01000005_gene2569	3.763e-151	495.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,2601W@186807|Peptococcaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158343_k127_1546895_39	765869.BDW_11285	1.733e-131	427.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2MTGD@213481|Bdellovibrionales,2WJI0@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158343_k127_1546895_186	1382359.JIAL01000001_gene2631	1.248e-22	109.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_1546895_119	443144.GM21_1935	2.103e-55	204.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,43UBJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158343_k127_1546895_76	1121468.AUBR01000026_gene2918	1.164e-87	302.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158343_k127_1546895_214	317936.Nos7107_3877	1.06e-09	62.0	2EDPD@1|root,33FME@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1546895_61	1340493.JNIF01000003_gene4582	1.506e-104	349.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158343_k127_1546895_85	204669.Acid345_3335	3.184e-80	291.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158343_k127_1546895_175	1120973.AQXL01000126_gene2983	8.776e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,1VBIF@1239|Firmicutes,4HKKH@91061|Bacilli,27A72@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_1546895_99	204669.Acid345_2890	2.971e-72	252.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158343_k127_1546895_100	401053.AciPR4_1852	5.856e-71	254.0	COG1127@1|root,COG1127@2|Bacteria,3Y3YI@57723|Acidobacteria,2JIF1@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158343_k127_1546895_127	240015.ACP_2954	3.227e-52	199.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158343_k127_1546895_192	211114.JOEF01000013_gene4977	7.461e-21	95.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4E75F@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158343_k127_1546895_11	635013.TherJR_1489	1.886e-211	686.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,260PA@186807|Peptococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158343_k127_1546895_158	383372.Rcas_1971	5.187e-37	148.0	COG0204@1|root,COG0204@2|Bacteria,2GAE1@200795|Chloroflexi,375Q3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158343_k127_1546895_70	457570.Nther_0307	1.931e-94	322.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158343_k127_1546895_111	1123252.ATZF01000015_gene1801	2.768e-62	219.0	COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,27CZS@186824|Thermoactinomycetaceae	91061|Bacilli	S	Mycothiol maleylpyruvate isomerase N-terminal domain	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1546895_37	635013.TherJR_2972	1.461e-132	437.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158343_k127_1546895_149	1267533.KB906734_gene4259	1.169e-38	150.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158343_k127_1546895_203	1423747.BAMJ01000006_gene589	3.361e-16	81.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae	91061|Bacilli	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158343_k127_1546895_184	1340493.JNIF01000004_gene998	1.836e-23	105.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria	57723|Acidobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158343_k127_1546895_130	234267.Acid_7094	4.613e-50	184.0	COG0193@1|root,COG0193@2|Bacteria,3Y48V@57723|Acidobacteria	57723|Acidobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158343_k127_1546895_165	1267534.KB906758_gene2516	1.48e-35	143.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158343_k127_1546895_52	639030.JHVA01000001_gene2821	1.81e-118	389.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria,2JHTF@204432|Acidobacteriia	204432|Acidobacteriia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158343_k127_1551147_114	1157490.EL26_11745	5.767e-54	201.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,277ZR@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
SRR25158343_k127_1551147_156	251229.Chro_1242	4.541e-22	104.0	COG2340@1|root,COG2340@2|Bacteria,1G6I4@1117|Cyanobacteria,3VK17@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158343_k127_1551147_125	204669.Acid345_4603	2.013e-42	178.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158343_k127_1551147_137	1267533.KB906735_gene4906	3.328e-32	142.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria,2JHVA@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR25158343_k127_1551147_86	479434.Sthe_1685	1.422e-75	259.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi,27Y7N@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158343_k127_1551147_198	1410665.JNKR01000015_gene1223	5.092e-05	53.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158343_k127_1551147_84	1347392.CCEZ01000043_gene521	8.987e-79	280.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,36DEN@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SRR25158343_k127_1551147_73	1408422.JHYF01000002_gene2597	7.882e-93	314.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,36EJW@31979|Clostridiaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158343_k127_1551147_23	857087.Metme_3269	2.442e-171	554.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XE21@135618|Methylococcales	135618|Methylococcales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
SRR25158343_k127_1551147_95	357808.RoseRS_2424	2.654e-65	225.0	COG0229@1|root,COG0229@2|Bacteria,2G78V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158343_k127_1551147_13	485913.Krac_7757	5.2e-197	628.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158343_k127_1551147_108	1382359.JIAL01000001_gene476	1.81e-56	201.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158343_k127_1551147_155	56107.Cylst_4203	8.36e-23	104.0	COG2340@1|root,COG2340@2|Bacteria,1G6DK@1117|Cyanobacteria,1HNBI@1161|Nostocales	1117|Cyanobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158343_k127_1551147_45	1340493.JNIF01000003_gene4781	1.891e-129	424.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158343_k127_1551147_124	1379698.RBG1_1C00001G0519	3.08e-43	169.0	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
SRR25158343_k127_1551147_126	278963.ATWD01000001_gene4283	1.658e-40	156.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria,2JJDW@204432|Acidobacteriia	204432|Acidobacteriia	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158343_k127_1551147_142	1121472.AQWN01000002_gene2321	2.205e-26	121.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,262G6@186807|Peptococcaceae	186801|Clostridia	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158343_k127_1551147_22	234267.Acid_7763	1.996e-173	570.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158343_k127_1551147_72	402626.Rpic_0375	5.898e-93	311.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2VH6D@28216|Betaproteobacteria,1K4P9@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158343_k127_1551147_50	1151292.QEW_0249	5.951e-122	406.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,25R7Z@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158343_k127_1551147_141	204669.Acid345_1209	7.697e-27	114.0	2DIW1@1|root,32UBV@2|Bacteria,3Y5BC@57723|Acidobacteria,2JJSS@204432|Acidobacteriia	204432|Acidobacteriia	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158343_k127_1551147_115	484770.UFO1_1595	6.021e-54	205.0	COG3509@1|root,COG3509@2|Bacteria,1TT77@1239|Firmicutes,4H3TQ@909932|Negativicutes	909932|Negativicutes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_144	1254432.SCE1572_26965	1.197e-25	119.0	COG4733@1|root,COG4733@2|Bacteria,1QR73@1224|Proteobacteria,4387I@68525|delta/epsilon subdivisions,2X3HE@28221|Deltaproteobacteria,2YW3T@29|Myxococcales	28221|Deltaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_33	234267.Acid_7841	2.401e-150	521.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1551147_24	443144.GM21_1039	5.006e-170	544.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2WU51@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Sodium:dicarboxylate symporter family	-	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
SRR25158343_k127_1551147_113	1267534.KB906755_gene4692	5.43e-54	212.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_132	1267533.KB906733_gene2988	3.873e-37	143.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1551147_152	234267.Acid_1101	7.059e-24	103.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1551147_8	99598.Cal7507_0398	6.44e-246	777.0	COG0531@1|root,COG0531@2|Bacteria,1G1I6@1117|Cyanobacteria,1HK4Y@1161|Nostocales	1117|Cyanobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_186	240015.ACP_0754	8.488e-07	61.0	COG1596@1|root,COG1596@2|Bacteria,3Y57H@57723|Acidobacteria,2JJNS@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158343_k127_1551147_129	903818.KI912268_gene2237	2.927e-39	156.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
SRR25158343_k127_1551147_80	121225.PHUM411890-PA	1.867e-82	281.0	COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria,41XDM@6656|Arthropoda,3SIYY@50557|Insecta,3ECTD@33342|Paraneoptera	33208|Metazoa	Q	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_1551147_110	404380.Gbem_0655	2.758e-54	212.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,43SU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158343_k127_1551147_29	518766.Rmar_1421	3.859e-156	505.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158343_k127_1551147_49	1479239.JQMU01000001_gene1077	7.377e-125	414.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_168	204669.Acid345_2988	2.5e-15	82.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158343_k127_1551147_25	316067.Geob_0363	3.765e-168	543.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria	1224|Proteobacteria	E	PFAM Peptidase S10, serine carboxypeptidase	MA20_31445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRR25158343_k127_1551147_145	118173.KB235910_gene5142	1.246e-25	111.0	COG2913@1|root,COG2913@2|Bacteria,1G7DP@1117|Cyanobacteria,1HBT7@1150|Oscillatoriales	1117|Cyanobacteria	J	Protein of unknown function (DUF3574)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3574
SRR25158343_k127_1551147_120	477974.Daud_1891	3.501e-46	171.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,261XV@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SRR25158343_k127_1551147_81	880070.Cycma_4887	1.841e-79	274.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,47KBM@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
SRR25158343_k127_1551147_64	483219.LILAB_27800	3.899e-104	350.0	COG3182@1|root,COG3182@2|Bacteria,1QWJM@1224|Proteobacteria,42T7A@68525|delta/epsilon subdivisions,2WX40@28221|Deltaproteobacteria,2YWR4@29|Myxococcales	28221|Deltaproteobacteria	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
SRR25158343_k127_1551147_30	1267533.KB906733_gene2952	5.214e-155	517.0	COG4774@1|root,COG4774@2|Bacteria,3Y313@57723|Acidobacteria	57723|Acidobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_1551147_21	518766.Rmar_0899	1.34e-175	567.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_1551147_0	234267.Acid_2395	0.0	1364.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria	57723|Acidobacteria	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158343_k127_1551147_70	1403819.BATR01000075_gene2158	7.822e-95	323.0	COG2374@1|root,COG2374@2|Bacteria,46XBV@74201|Verrucomicrobia,2IVCM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_6	1123277.KB893180_gene2478	2.183e-256	803.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,47N05@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_1551147_54	204669.Acid345_1879	8.337e-112	371.0	COG0812@1|root,COG0812@2|Bacteria,3Y3AT@57723|Acidobacteria,2JIMJ@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158343_k127_1551147_150	1385935.N836_03830	2.653e-24	119.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158343_k127_1551147_10	204669.Acid345_4753	8.608e-228	726.0	COG0480@1|root,COG0480@2|Bacteria,3Y2RR@57723|Acidobacteria,2JI85@204432|Acidobacteriia	204432|Acidobacteriia	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_1551147_189	985053.VMUT_0169	4.408e-06	60.0	arCOG03700@1|root,arCOG03700@2157|Archaea,2XQSN@28889|Crenarchaeota	28889|Crenarchaeota	C	Blue copper protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158343_k127_1551147_56	1123248.KB893381_gene1105	2.57e-110	381.0	COG3667@1|root,COG3667@2|Bacteria,4NICY@976|Bacteroidetes,1IWVR@117747|Sphingobacteriia	976|Bacteroidetes	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_131	857087.Metme_1480	1.428e-37	145.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1S459@1236|Gammaproteobacteria,1XFIP@135618|Methylococcales	135618|Methylococcales	K	MerR, DNA binding	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158343_k127_1551147_97	1280953.HOC_07544	2.681e-63	221.0	COG3544@1|root,COG3544@2|Bacteria,1MVU8@1224|Proteobacteria,2TSBT@28211|Alphaproteobacteria,43XDF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158343_k127_1551147_2	886293.Sinac_2520	9.18e-288	916.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158343_k127_1551147_60	929556.Solca_3257	6.793e-106	353.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1IQI3@117747|Sphingobacteriia	976|Bacteroidetes	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158343_k127_1551147_1	1183438.GKIL_2419	2.92e-321	1006.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1G141@1117|Cyanobacteria	1117|Cyanobacteria	HJM	Mur ligase family, glutamate ligase domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
SRR25158343_k127_1551147_91	251221.35214701	7.961e-70	246.0	COG4242@1|root,COG4242@2|Bacteria,1G05A@1117|Cyanobacteria	1117|Cyanobacteria	E	Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158343_k127_1551147_205	714943.Mucpa_3716	0.0007647	44.0	2EK7X@1|root,33DY9@2|Bacteria,4NYAQ@976|Bacteroidetes,1IUER@117747|Sphingobacteriia	976|Bacteroidetes	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
SRR25158343_k127_1551147_27	1379270.AUXF01000004_gene3268	8.332e-163	535.0	COG0370@1|root,COG0370@2|Bacteria,1ZT1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158343_k127_1551147_167	1121344.JHZO01000006_gene1936	9.668e-16	79.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SRR25158343_k127_1551147_94	1232410.KI421428_gene1213	8.912e-66	232.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,43S93@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158343_k127_1551147_179	903818.KI912268_gene1794	8.1e-10	71.0	COG0457@1|root,COG0457@2|Bacteria,3Y8SB@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2
SRR25158343_k127_1551147_171	1131269.AQVV01000001_gene1393	6.245e-14	77.0	2CBGA@1|root,33A66@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_11	234267.Acid_0067	9.504e-205	647.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158343_k127_1551147_190	1121396.KB893057_gene2516	6.928e-06	55.0	COG4968@1|root,COG4968@2|Bacteria,1QNMD@1224|Proteobacteria,43A72@68525|delta/epsilon subdivisions,2WYJP@28221|Deltaproteobacteria,2MNPY@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
SRR25158343_k127_1551147_16	903818.KI912268_gene772	3.484e-184	595.0	COG1166@1|root,COG1166@2|Bacteria,3Y449@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SRR25158343_k127_1551147_99	1379698.RBG1_1C00001G0709	5.084e-62	226.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158343_k127_1551147_107	1304885.AUEY01000032_gene2006	2.799e-57	210.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2MJAD@213118|Desulfobacterales	28221|Deltaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158343_k127_1551147_197	706587.Desti_5023	3.477e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WQ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158343_k127_1551147_187	1122243.KB903804_gene2114	1.007e-06	54.0	2ESQJ@1|root,33K90@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_177	675806.VII_003470	6.596e-11	74.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1XUWY@135623|Vibrionales	135623|Vibrionales	M	Periplasmic protein involved in polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158343_k127_1551147_61	926692.AZYG01000056_gene470	1.207e-105	364.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WADN@53433|Halanaerobiales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158343_k127_1551147_78	1122182.KB903834_gene5898	6.997e-84	288.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria,4DJFC@85008|Micromonosporales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR25158343_k127_1551147_139	945713.IALB_2664	1.524e-29	124.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158343_k127_1551147_51	1123054.KB907701_gene1840	5.739e-115	383.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria,1RS7W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	proteins of the AP superfamily	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
SRR25158343_k127_1551147_199	1379270.AUXF01000001_gene1922	0.0001185	49.0	2EKHJ@1|root,33E7I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_14	1267535.KB906767_gene5021	6.732e-193	610.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	204432|Acidobacteriia	J	class II (D K	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158343_k127_1551147_7	1340493.JNIF01000004_gene652	9.102e-247	775.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1551147_140	1340493.JNIF01000004_gene653	8.333e-28	119.0	2D0AC@1|root,32T87@2|Bacteria,3Y56N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_134	706587.Desti_1483	1.873e-35	148.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158343_k127_1551147_123	449447.MAE_40260	1.021e-44	175.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1G1A0@1117|Cyanobacteria	1117|Cyanobacteria	GJM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158343_k127_1551147_176	177437.HRM2_35960	4.718e-11	72.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MISA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158343_k127_1551147_102	1408422.JHYF01000009_gene1999	1.993e-59	216.0	COG3635@1|root,COG3635@2|Bacteria,1UIDA@1239|Firmicutes,25EIA@186801|Clostridia	186801|Clostridia	G	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
SRR25158343_k127_1551147_37	316274.Haur_2328	2.375e-145	473.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi,374W1@32061|Chloroflexia	32061|Chloroflexia	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158343_k127_1551147_118	264462.Bd3503	1.317e-47	182.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WR0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158343_k127_1551147_9	477974.Daud_0168	2.622e-230	727.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158343_k127_1551147_69	1121123.AUAO01000001_gene890	2.105e-95	330.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1551147_35	450851.PHZ_c3416	1.105e-148	482.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1551147_46	1121920.AUAU01000004_gene638	3.914e-127	411.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158343_k127_1551147_178	1267535.KB906767_gene2973	5.468e-10	67.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_28	1267533.KB906733_gene3318	2.253e-160	514.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158343_k127_1551147_68	1279009.ADICEAN_01094	1.571e-95	317.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47U3U@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SRR25158343_k127_1551147_88	1211114.ALIP01000035_gene1658	1.879e-73	250.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,1S3V3@1236|Gammaproteobacteria,1XCRM@135614|Xanthomonadales	135614|Xanthomonadales	FJ	MafB19-like deaminase	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158343_k127_1551147_43	1239962.C943_00207	2.927e-132	432.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia	976|Bacteroidetes	E	PFAM Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158343_k127_1551147_5	1185876.BN8_02352	2.424e-265	822.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158343_k127_1551147_48	714943.Mucpa_2188	4.446e-126	415.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_1551147_105	448385.sce5075	3.87e-58	221.0	COG2339@1|root,COG3266@1|root,COG2339@2|Bacteria,COG3266@2|Bacteria,1P8NV@1224|Proteobacteria	1224|Proteobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158343_k127_1551147_182	471853.Bcav_2102	8.35e-09	68.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158343_k127_1551147_82	1267535.KB906767_gene5353	3.92e-79	275.0	COG0142@1|root,COG0142@2|Bacteria,3Y2VJ@57723|Acidobacteria,2JHS0@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158343_k127_1551147_103	1382359.JIAL01000001_gene117	1.212e-58	208.0	COG1666@1|root,COG1666@2|Bacteria,3Y4I3@57723|Acidobacteria,2JJ8P@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158343_k127_1551147_89	204669.Acid345_2029	6.887e-73	254.0	COG0084@1|root,COG0084@2|Bacteria,3Y4DK@57723|Acidobacteria,2JJ1I@204432|Acidobacteriia	204432|Acidobacteriia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158343_k127_1551147_196	1128427.KB904821_gene3381	3.299e-05	53.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158343_k127_1551147_19	1382359.JIAL01000001_gene119	2.52e-177	578.0	COG0143@1|root,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria,2JIC5@204432|Acidobacteriia	204432|Acidobacteriia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158343_k127_1551147_39	234267.Acid_6511	6.188e-143	472.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria	57723|Acidobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158343_k127_1551147_193	983548.Krodi_0920	1.271e-05	50.0	2APBA@1|root,31EDH@2|Bacteria,4NPIT@976|Bacteroidetes,1I25X@117743|Flavobacteriia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158343_k127_1551147_90	1047013.AQSP01000047_gene2586	1.79e-72	248.0	COG0302@1|root,COG0302@2|Bacteria,2NPE9@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659	2.7.6.3,3.5.4.16	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R03503,R04639,R05046,R05048	RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0928,iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158343_k127_1551147_119	398525.KB900701_gene3804	8.264e-47	177.0	COG0500@1|root,COG2226@2|Bacteria,1RF1C@1224|Proteobacteria,2U86S@28211|Alphaproteobacteria,3JXW1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1551147_66	697281.Mahau_1643	8.898e-104	349.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,42FR9@68295|Thermoanaerobacterales	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158343_k127_1551147_15	278963.ATWD01000002_gene307	2.226e-187	606.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158343_k127_1551147_40	240015.ACP_2753	1.593e-136	441.0	COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158343_k127_1551147_148	1131269.AQVV01000006_gene488	9.378e-25	116.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000006_gene488|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_202	1123075.AUDP01000016_gene3411	0.0003381	48.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3,HTH_31
SRR25158343_k127_1551147_183	926554.KI912631_gene3552	4.157e-08	65.0	COG4712@1|root,COG4712@2|Bacteria,1WIU2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Rad52 22 double-strand break repair protein	ddrA	GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701	-	-	-	-	-	-	-	-	-	-	Rad52_Rad22
SRR25158343_k127_1551147_151	304371.MCP_1472	3.942e-24	102.0	COG4895@1|root,arCOG04920@2157|Archaea,2Y0A3@28890|Euryarchaeota,2NB4K@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
SRR25158343_k127_1551147_122	671143.DAMO_2474	9.231e-45	166.0	COG1793@1|root,COG1793@2|Bacteria,2NR3Z@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase Ligase (LigD)	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158343_k127_1551147_77	517418.Ctha_1581	1.055e-86	308.0	COG0612@1|root,COG0612@2|Bacteria,1FEWA@1090|Chlorobi	1090|Chlorobi	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1551147_71	1122179.KB890458_gene744	3.304e-94	325.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1551147_111	1370125.AUWT01000032_gene1634	3.092e-54	199.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158343_k127_1551147_173	112098.XP_008613245.1	8.847e-13	78.0	KOG3689@1|root,KOG3689@2759|Eukaryota	2759|Eukaryota	T	3',5'-cyclic-nucleotide phosphodiesterase activity	-	-	3.1.4.53	ko:K13294	ko00230,map00230	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	GAF,PDEase_I
SRR25158343_k127_1551147_75	1340493.JNIF01000003_gene2530	2.687e-91	321.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158343_k127_1551147_42	1340493.JNIF01000003_gene3549	8.313e-135	469.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_1551147_128	762903.Pedsa_0002	2.112e-39	159.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158343_k127_1551147_38	1499967.BAYZ01000173_gene5813	3.717e-145	487.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
SRR25158343_k127_1551147_138	1173026.Glo7428_2473	2.157e-30	132.0	COG3842@1|root,COG3842@2|Bacteria,1G1HQ@1117|Cyanobacteria	1117|Cyanobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158343_k127_1551147_121	1267535.KB906767_gene3728	4.998e-45	182.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158343_k127_1551147_44	401053.AciPR4_1306	1.762e-129	434.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria,2JI79@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1551147_96	350688.Clos_1421	8.064e-64	229.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,36ED0@31979|Clostridiaceae	186801|Clostridia	S	tigr00255	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158343_k127_1551147_206	330214.NIDE2463	0.0008835	45.0	COG1758@1|root,COG1758@2|Bacteria,3J0UJ@40117|Nitrospirae	40117|Nitrospirae	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158343_k127_1551147_117	309803.CTN_0876	1.508e-52	193.0	COG0194@1|root,COG0194@2|Bacteria,2GD0U@200918|Thermotogae	200918|Thermotogae	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158343_k127_1551147_184	904314.SEVCU012_0633	9.76e-08	57.0	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	csbD	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158343_k127_1551147_12	204669.Acid345_3065	1.48e-199	636.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
SRR25158343_k127_1551147_116	204669.Acid345_4529	3.748e-53	197.0	2D4UK@1|root,32THN@2|Bacteria,3Y59Q@57723|Acidobacteria,2JK20@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142
SRR25158343_k127_1551147_74	204669.Acid345_4530	9.644e-92	332.0	COG4805@1|root,COG4805@2|Bacteria,3Y4PP@57723|Acidobacteria,2JKV8@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_164	485916.Dtox_3979	2.362e-18	98.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
SRR25158343_k127_1551147_41	1121904.ARBP01000005_gene4802	6.879e-136	443.0	COG0438@1|root,COG0438@2|Bacteria,4NKMC@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1551147_163	1121904.ARBP01000005_gene4801	1.465e-19	99.0	2APV8@1|root,31EZQ@2|Bacteria,4P91U@976|Bacteroidetes,47WG9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_185	349521.HCH_00081	1.55e-07	57.0	2EJJ6@1|root,33DA3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_55	313606.M23134_06161	2.003e-110	371.0	COG0438@1|root,COG0438@2|Bacteria,4NM4W@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1551147_146	313606.M23134_06285	5.465e-25	113.0	2EBPK@1|root,335PP@2|Bacteria,4NWAZ@976|Bacteroidetes,47W5A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_106	313606.M23134_06286	1.498e-57	211.0	2DC71@1|root,32TZ3@2|Bacteria,4NWF7@976|Bacteroidetes,47VGS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_34	682795.AciX8_1960	3.716e-149	484.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158343_k127_1551147_149	1324957.K933_11981	2.503e-24	120.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23TI5@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_1551147_160	101510.RHA1_ro00504	7.32e-21	101.0	COG0515@1|root,COG0515@2|Bacteria,2I34D@201174|Actinobacteria,4G9JR@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_204	591001.Acfer_0023	0.0006346	50.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
SRR25158343_k127_1551147_63	204669.Acid345_3700	3.722e-105	351.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria,2JP3Y@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158343_k127_1551147_85	278963.ATWD01000001_gene2060	1.418e-77	267.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria,2JK7K@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158343_k127_1551147_17	234267.Acid_1167	4.621e-178	566.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158343_k127_1551147_153	867903.ThesuDRAFT_00305	1.273e-23	103.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WCPE@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158343_k127_1551147_65	316067.Geob_2613	5.653e-104	346.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158343_k127_1551147_58	316067.Geob_2612	2.385e-109	363.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158343_k127_1551147_174	1089552.KI911559_gene2362	1.163e-12	69.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2JTZ3@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158343_k127_1551147_147	1340493.JNIF01000004_gene723	7.49e-25	110.0	COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158343_k127_1551147_62	926549.KI421517_gene1430	1.461e-105	353.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158343_k127_1551147_98	1089553.Tph_c14490	2.866e-63	222.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,42G0W@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
SRR25158343_k127_1551147_52	1232410.KI421413_gene593	1.122e-113	374.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158343_k127_1551147_31	204669.Acid345_1052	1.481e-153	518.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_1551147_109	234267.Acid_7677	1.287e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_1551147_181	1242864.D187_003591	2.941e-09	70.0	COG1361@1|root,COG3828@1|root,COG1361@2|Bacteria,COG3828@2|Bacteria,1MUQC@1224|Proteobacteria,434JE@68525|delta/epsilon subdivisions,2WYWK@28221|Deltaproteobacteria,2Z0T7@29|Myxococcales	28221|Deltaproteobacteria	M	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M11,Reprolysin_5,RicinB_lectin_2
SRR25158343_k127_1551147_172	384765.SIAM614_16512	1.326e-13	84.0	COG4249@1|root,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Peptidase C14 caspase catalytic subunit p20	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	PG_binding_1,Peptidase_C14,Sel1
SRR25158343_k127_1551147_200	1380391.JIAS01000012_gene4259	0.0002182	53.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TR94@28211|Alphaproteobacteria,2JWIY@204441|Rhodospirillales	204441|Rhodospirillales	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158343_k127_1551147_166	745718.JADT01000009_gene2948	3.285e-17	86.0	COG1470@1|root,COG2273@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2273@2|Bacteria,COG2931@2|Bacteria,4NJKV@976|Bacteroidetes,1I018@117743|Flavobacteriia	976|Bacteroidetes	Q	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase2,BACON,Big_2,F5_F8_type_C
SRR25158343_k127_1551147_188	1121127.JAFA01000009_gene6874	1.435e-06	54.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria,1K230@119060|Burkholderiaceae	28216|Betaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
SRR25158343_k127_1551147_175	1173028.ANKO01000158_gene4535	6.68e-12	76.0	COG1357@1|root,COG1357@2|Bacteria,1G4KR@1117|Cyanobacteria,1HAY3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158343_k127_1551147_127	1157708.KB907450_gene5521	4.283e-40	155.0	2DR9C@1|root,33AS0@2|Bacteria,1NJ0U@1224|Proteobacteria,2VYD2@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_161	65393.PCC7424_4683	6.18e-20	89.0	2C1SS@1|root,32YN6@2|Bacteria,1G9HK@1117|Cyanobacteria,3KKJV@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_159	247490.KSU1_C0079	3.398e-21	94.0	2E90H@1|root,31X4M@2|Bacteria,2J4J2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_104	1450525.JATV01000029_gene2314	2.357e-58	215.0	COG2865@1|root,COG2865@2|Bacteria,4NTCY@976|Bacteroidetes	976|Bacteroidetes	K	Domain of unknown function (DUF4062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
SRR25158343_k127_1551147_32	269799.Gmet_1770	2.151e-153	495.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158343_k127_1551147_18	1123277.KB893181_gene2296	4.946e-178	574.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158343_k127_1551147_101	1449126.JQKL01000042_gene1038	1.904e-61	223.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,268HU@186813|unclassified Clostridiales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_1551147_67	497964.CfE428DRAFT_4880	7.08e-100	344.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,46T28@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_31
SRR25158343_k127_1551147_79	1121374.KB891586_gene2441	1.985e-83	294.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158343_k127_1551147_135	335543.Sfum_3315	5.396e-34	139.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42W4B@68525|delta/epsilon subdivisions,2WP0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158343_k127_1551147_36	1519464.HY22_10910	7.194e-146	477.0	COG0277@1|root,COG0277@2|Bacteria,1FDCI@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158343_k127_1551147_165	153721.MYP_4620	2.753e-17	89.0	2EKCZ@1|root,33E39@2|Bacteria,4NXWT@976|Bacteroidetes,47VYQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_3	1232410.KI421424_gene1738	1.215e-268	841.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43S6K@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Ultra-violet resistance protein B	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158343_k127_1551147_158	639282.DEFDS_2033	3.048e-21	108.0	COG3210@1|root,COG3591@1|root,COG5513@1|root,COG3210@2|Bacteria,COG3591@2|Bacteria,COG5513@2|Bacteria	2|Bacteria	G	serine-type aminopeptidase activity	-	-	-	ko:K02030,ko:K14475	ko05143,map05143	M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	Inhibitor_I42
SRR25158343_k127_1551147_26	682795.AciX8_3108	1.647e-166	551.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y719@57723|Acidobacteria,2JKBH@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8,Trans_reg_C
SRR25158343_k127_1551147_157	926556.Echvi_2928	4.989e-22	103.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,47PUA@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158343_k127_1551147_57	247490.KSU1_C1189	1.526e-109	361.0	COG0152@1|root,COG0152@2|Bacteria,2IY7D@203682|Planctomycetes	203682|Planctomycetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158343_k127_1551147_195	56780.SYN_01756	2.53e-05	57.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria	1224|Proteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
SRR25158343_k127_1551147_201	1219076.N646_2812	0.0002306	49.0	COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,1SHTN@1236|Gammaproteobacteria,1Y2B5@135623|Vibrionales	135623|Vibrionales	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SRR25158343_k127_1551147_191	903818.KI912269_gene198	7.896e-06	51.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
SRR25158343_k127_1551147_83	1048983.EL17_13435	7.754e-79	272.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia	976|Bacteroidetes	S	beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158343_k127_1551147_130	1382359.JIAL01000001_gene1679	4.856e-38	145.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria,2JJEF@204432|Acidobacteriia	204432|Acidobacteriia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158343_k127_1551147_4	234267.Acid_6747	5.244e-266	827.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158343_k127_1551147_162	197221.22296197	1.231e-19	95.0	COG0783@1|root,COG0783@2|Bacteria,1G4ZH@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR25158343_k127_1551147_170	234267.Acid_2436	4.873e-14	86.0	COG3170@1|root,COG3170@2|Bacteria,3Y4RX@57723|Acidobacteria	57723|Acidobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1551147_100	323848.Nmul_A1191	6.74e-62	236.0	COG0642@1|root,COG0784@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,2WHH7@28216|Betaproteobacteria,372Y3@32003|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
SRR25158343_k127_1551147_59	945713.IALB_1309	1.796e-106	363.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1551147_53	1173024.KI912149_gene5690	2.345e-112	387.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JK6C@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158343_k127_1551147_20	272123.Anacy_1360	2.058e-176	568.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1HKB6@1161|Nostocales	1117|Cyanobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158343_k127_1551147_169	1322246.BN4_10330	3.602e-14	79.0	COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
SRR25158343_k127_1551147_93	1354303.M917_0523	5.358e-67	231.0	arCOG10217@1|root,301DU@2|Bacteria,1RDN4@1224|Proteobacteria,1S2BK@1236|Gammaproteobacteria,3NKY2@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4385
SRR25158343_k127_1551147_112	240015.ACP_1741	5.299e-54	207.0	COG1668@1|root,COG1668@2|Bacteria,3Y2XV@57723|Acidobacteria,2JIQK@204432|Acidobacteriia	204432|Acidobacteriia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158343_k127_1551147_76	1047013.AQSP01000052_gene2600	2.907e-90	306.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_1551147_92	697303.Thewi_2044	8.016e-69	246.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158343_k127_1551147_143	1286106.MPL1_05474	4.901e-26	114.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,46126@72273|Thiotrichales	72273|Thiotrichales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
SRR25158343_k127_1551147_47	639030.JHVA01000001_gene3551	4.687e-127	420.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158343_k127_1551147_87	204669.Acid345_2146	1.833e-74	277.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
SRR25158343_k127_1551147_154	929703.KE386491_gene280	4.816e-23	98.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,47Q5C@768503|Cytophagia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_165	873517.HMPREF1977_0829	4.346e-13	71.0	COG0338@1|root,COG0338@2|Bacteria,4NFZ2@976|Bacteroidetes,1I484@117743|Flavobacteriia,1EREU@1016|Capnocytophaga	976|Bacteroidetes	L	DNA adenine methylase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158343_k127_1631683_65	1298608.JCM18900_257	3.15e-100	332.0	28IMK@1|root,2Z8N2@2|Bacteria,1R85A@1224|Proteobacteria,1SIWB@1236|Gammaproteobacteria,3NR87@468|Moraxellaceae	1236|Gammaproteobacteria	L	Dam-replacing family	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DpnI
SRR25158343_k127_1631683_152	1121887.AUDK01000017_gene83	8.502e-22	97.0	28U4R@1|root,2ZGAN@2|Bacteria,4P9AF@976|Bacteroidetes,1IDX5@117743|Flavobacteriia,2NZE6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_75	761193.Runsl_4413	9.56e-87	288.0	COG0338@1|root,COG0338@2|Bacteria,4NRXP@976|Bacteroidetes	976|Bacteroidetes	L	DNA N-6-adenine-methyltransferase (Dam)	-	-	-	-	-	-	-	-	-	-	-	-	Dam
SRR25158343_k127_1631683_182	520999.PROVALCAL_03402	0.0001037	51.0	2E38J@1|root,32Y88@2|Bacteria,1NDNB@1224|Proteobacteria,1SDFI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VRR_NUC	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
SRR25158343_k127_1631683_164	1129374.AJE_08175	5.23e-14	77.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,1S5X5@1236|Gammaproteobacteria,46B0E@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)	umuD	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009355,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158343_k127_1631683_178	755732.Fluta_1019	5.225e-05	54.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158343_k127_1631683_5	234267.Acid_4922	5.04e-322	1000.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158343_k127_1631683_185	1122917.KB899662_gene2225	0.0008567	50.0	COG0457@1|root,COG0457@2|Bacteria,1V04B@1239|Firmicutes,4HBW4@91061|Bacilli,26QAG@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_1631683_162	1248760.ANFZ01000009_gene1181	2.46e-15	81.0	COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,2K5J6@204457|Sphingomonadales	204457|Sphingomonadales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_1631683_159	1408813.AYMG01000016_gene4823	2.056e-16	84.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,1IQT0@117747|Sphingobacteriia	976|Bacteroidetes	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1631683_145	697282.Mettu_0249	5.911e-25	105.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,1XGRY@135618|Methylococcales	135618|Methylococcales	S	PFAM ChaB	-	-	-	-	-	-	-	-	-	-	-	-	ChaB
SRR25158343_k127_1631683_160	1296416.JACB01000001_gene3358	2.497e-16	90.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia,2YKRI@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_1631683_42	269799.Gmet_0555	1.931e-132	437.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1631683_17	1173024.KI912149_gene5262	3.447e-224	711.0	COG1816@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG5278@1|root,COG1816@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5278@2|Bacteria,1GK1J@1117|Cyanobacteria,1JKBT@1189|Stigonemataceae	1117|Cyanobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158343_k127_1631683_135	234267.Acid_1758	6.679e-35	141.0	COG3245@1|root,COG3245@2|Bacteria,3Y5B1@57723|Acidobacteria	57723|Acidobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_132	234267.Acid_1757	1.759e-36	144.0	COG0789@1|root,COG0789@2|Bacteria,3Y5XK@57723|Acidobacteria	57723|Acidobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
SRR25158343_k127_1631683_177	926550.CLDAP_10820	9.277e-06	57.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
SRR25158343_k127_1631683_183	1173027.Mic7113_0190	0.0004641	51.0	COG0515@1|root,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H7V1@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	Pkinase,WD40
SRR25158343_k127_1631683_91	765420.OSCT_1703	6.565e-68	251.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_1631683_37	871963.Desdi_3516	1.078e-145	469.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,260HS@186807|Peptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158343_k127_1631683_179	1380386.JIAW01000011_gene3279	5.27e-05	53.0	2F87F@1|root,340KP@2|Bacteria,2GW0D@201174|Actinobacteria,2332C@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_184	247639.MGP2080_07092	0.0006758	48.0	2F1PW@1|root,33UQ6@2|Bacteria,1RHX8@1224|Proteobacteria,1SPAN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_137	395493.BegalDRAFT_1726	7.11e-34	139.0	COG5497@1|root,COG5497@2|Bacteria,1RCFU@1224|Proteobacteria	1224|Proteobacteria	S	secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2259
SRR25158343_k127_1631683_98	1121091.AUMP01000024_gene3001	6.113e-56	201.0	COG1670@1|root,COG1670@2|Bacteria,1V5WS@1239|Firmicutes,4HH37@91061|Bacilli	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158343_k127_1631683_61	1121920.AUAU01000012_gene2645	3.482e-106	353.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158343_k127_1631683_154	65093.PCC7418_3086	1.958e-20	94.0	COG0681@1|root,COG0681@2|Bacteria,1GA6F@1117|Cyanobacteria	1117|Cyanobacteria	U	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158343_k127_1631683_48	518766.Rmar_1677	7.456e-122	398.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,1FIN7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158343_k127_1631683_129	1283283.ATXA01000026_gene3703	1.305e-37	142.0	2E3IE@1|root,32YGW@2|Bacteria,2GRK7@201174|Actinobacteria	201174|Actinobacteria	S	Hexameric tyrosine-coordinated heme protein (HTHP)	-	-	-	-	-	-	-	-	-	-	-	-	HTHP
SRR25158343_k127_1631683_59	266117.Rxyl_2537	1.617e-107	361.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CPHX@84995|Rubrobacteria	84995|Rubrobacteria	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158343_k127_1631683_124	1355374.JARU01000020_gene893	1.783e-39	151.0	COG1310@1|root,COG1310@2|Bacteria,1N3TI@1224|Proteobacteria,42TY4@68525|delta/epsilon subdivisions,2YQAW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158343_k127_1631683_21	1268072.PSAB_02820	1.139e-198	635.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,271Z6@186822|Paenibacillaceae	91061|Bacilli	H	ThiS family	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
SRR25158343_k127_1631683_60	78245.Xaut_2363	2.102e-107	350.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,3EYMY@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158343_k127_1631683_89	1121920.AUAU01000004_gene671	1.227e-73	258.0	COG3358@1|root,COG3358@2|Bacteria,3Y4K1@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158343_k127_1631683_85	682795.AciX8_4669	5.877e-76	261.0	COG0605@1|root,COG0605@2|Bacteria,3Y2HD@57723|Acidobacteria,2JIMM@204432|Acidobacteriia	204432|Acidobacteriia	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158343_k127_1631683_130	1460634.JCM19037_339	2.253e-37	143.0	COG0633@1|root,COG0633@2|Bacteria,1VAB4@1239|Firmicutes,4HM5K@91061|Bacilli	91061|Bacilli	C	2Fe-2S iron-sulfur cluster binding domain	fdx5	-	-	-	-	-	-	-	-	-	-	-	Fer2
SRR25158343_k127_1631683_87	945713.IALB_0353	1.055e-74	259.0	COG0101@1|root,COG0101@2|Bacteria	2|Bacteria	J	tRNA pseudouridine synthase activity	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158343_k127_1631683_141	391625.PPSIR1_04398	2.346e-28	119.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158343_k127_1631683_108	240015.ACP_0264	5.328e-48	180.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158343_k127_1631683_126	1267535.KB906767_gene3955	5.753e-39	160.0	COG0628@1|root,COG0628@2|Bacteria,3Y4YN@57723|Acidobacteria	57723|Acidobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158343_k127_1631683_39	671143.DAMO_2140	1.38e-136	443.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
SRR25158343_k127_1631683_121	1267535.KB906767_gene404	2.118e-40	158.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria,2JJ4I@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158343_k127_1631683_90	1131269.AQVV01000024_gene2355	2.345e-73	260.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158343_k127_1631683_100	1382359.JIAL01000001_gene2308	3.163e-55	201.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_1631683_49	1379698.RBG1_1C00001G0675	1.449e-121	400.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158343_k127_1631683_157	1267535.KB906767_gene2260	2.065e-19	95.0	COG3584@1|root,COG3584@2|Bacteria,3Y8W5@57723|Acidobacteria	57723|Acidobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
SRR25158343_k127_1631683_62	1174528.JH992892_gene6585	1.127e-105	350.0	COG2080@1|root,COG2080@2|Bacteria,1G3HY@1117|Cyanobacteria,1JH45@1189|Stigonemataceae	1117|Cyanobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158343_k127_1631683_32	1185876.BN8_02237	1.762e-156	499.0	COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,47P3C@768503|Cytophagia	976|Bacteroidetes	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4,1.2.5.3	ko:K03519,ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158343_k127_1631683_9	1185876.BN8_02238	6.358e-296	923.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,47TB7@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158343_k127_1631683_125	211114.JOEF01000004_gene6689	2.671e-39	152.0	2BHI3@1|root,32BKG@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158343_k127_1631683_19	927677.ALVU02000001_gene4113	7.744e-217	696.0	COG1529@1|root,COG1529@2|Bacteria,1G35M@1117|Cyanobacteria	1117|Cyanobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158343_k127_1631683_77	700598.Niako_5873	3.618e-85	287.0	COG0702@1|root,COG0702@2|Bacteria,4NGMR@976|Bacteroidetes,1ISJA@117747|Sphingobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158343_k127_1631683_10	1174528.JH992892_gene6587	1.469e-291	912.0	COG1529@1|root,COG1529@2|Bacteria,1G35M@1117|Cyanobacteria,1JHKP@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158343_k127_1631683_70	927677.ALVU02000001_gene4114	4.098e-93	317.0	COG1975@1|root,COG1975@2|Bacteria,1G2SP@1117|Cyanobacteria	1117|Cyanobacteria	O	maturation factor XdhC CoxF family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
SRR25158343_k127_1631683_110	1173027.Mic7113_0394	2.181e-47	177.0	COG2068@1|root,COG2068@2|Bacteria,1G608@1117|Cyanobacteria,1HBPU@1150|Oscillatoriales	1117|Cyanobacteria	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158343_k127_1631683_171	1121015.N789_12070	7.754e-09	62.0	2APC5@1|root,31EED@2|Bacteria,1QBPZ@1224|Proteobacteria,1T79X@1236|Gammaproteobacteria,1X904@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_53	1267534.KB906756_gene293	2.326e-116	386.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1631683_25	1217656.F964_01674	1.431e-190	602.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,3NM33@468|Moraxellaceae	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158343_k127_1631683_63	373994.Riv7116_3111	4.022e-104	346.0	COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,1HJG6@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158343_k127_1631683_117	32049.SYNPCC7002_A1401	5.44e-45	175.0	COG0248@1|root,COG0248@2|Bacteria,1FZZC@1117|Cyanobacteria,1GYWM@1129|Synechococcus	1117|Cyanobacteria	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158343_k127_1631683_175	1121930.AQXG01000019_gene82	5.25e-06	50.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes	976|Bacteroidetes	F	Creatinine amidohydrolase	crnA	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158343_k127_1631683_158	1198114.AciX9_2169	4.479e-18	92.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_1631683_51	1120965.AUBV01000001_gene3515	1.065e-118	388.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158343_k127_1631683_93	648996.Theam_1712	7.308e-66	233.0	COG0496@1|root,COG0496@2|Bacteria,2G3WU@200783|Aquificae	200783|Aquificae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158343_k127_1631683_166	1198114.AciX9_3417	2.002e-12	70.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria,2JJWG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158343_k127_1631683_7	1382359.JIAL01000001_gene12	7.182e-308	957.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158343_k127_1631683_38	240015.ACP_0140	1.838e-144	471.0	COG1109@1|root,COG1109@2|Bacteria,3Y2Y6@57723|Acidobacteria,2JHZU@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158343_k127_1631683_67	1121930.AQXG01000003_gene2510	6.823e-94	317.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1IQR5@117747|Sphingobacteriia	976|Bacteroidetes	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158343_k127_1631683_16	485913.Krac_10606	2.616e-231	724.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi	200795|Chloroflexi	C	PFAM amine oxidase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158343_k127_1631683_103	1123372.AUIT01000002_gene131	5.283e-52	192.0	COG0744@1|root,COG0744@2|Bacteria,2GHUC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRR25158343_k127_1631683_118	439235.Dalk_0228	1.563e-43	163.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,2MJVE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158343_k127_1631683_36	349161.Dred_1346	6.981e-149	490.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
SRR25158343_k127_1631683_64	330214.NIDE1256	4.475e-103	351.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1631683_84	933262.AXAM01000030_gene825	3.338e-76	273.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2MJ4J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
SRR25158343_k127_1631683_107	1434929.X946_4823	2.772e-48	185.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,1K5CY@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
SRR25158343_k127_1631683_138	383372.Rcas_1566	1.906e-32	133.0	2EB79@1|root,3357W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_128	234267.Acid_6218	1.155e-37	158.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_1631683_147	869213.JCM21142_93956	5.786e-24	105.0	COG0784@1|root,COG0784@2|Bacteria,4P2B8@976|Bacteroidetes	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158343_k127_1631683_173	765420.OSCT_1730	9.179e-08	63.0	COG0457@1|root,COG0457@2|Bacteria,2GBDY@200795|Chloroflexi,375DC@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
SRR25158343_k127_1631683_146	1122622.ATWJ01000010_gene1306	5.619e-24	106.0	2BCV5@1|root,326FU@2|Bacteria,2HBXJ@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_46	204669.Acid345_1443	1.364e-127	425.0	COG1012@1|root,COG1012@2|Bacteria,3Y6J2@57723|Acidobacteria,2JMD6@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158343_k127_1631683_41	204669.Acid345_2716	8.426e-133	459.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158343_k127_1631683_127	886293.Sinac_2076	8.364e-39	150.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158343_k127_1631683_80	1536774.H70357_29815	2.604e-81	282.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158343_k127_1631683_13	639282.DEFDS_1463	1.433e-255	816.0	COG0013@1|root,COG0013@2|Bacteria,2GF1K@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158343_k127_1631683_76	1120973.AQXL01000132_gene2193	1.64e-85	295.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,27A7C@186823|Alicyclobacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158343_k127_1631683_54	1267535.KB906767_gene577	4.351e-116	394.0	COG0497@1|root,COG0497@2|Bacteria,3Y2J4@57723|Acidobacteria,2JI9C@204432|Acidobacteriia	204432|Acidobacteriia	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158343_k127_1631683_115	316067.Geob_2055	3.277e-46	169.0	COG0590@1|root,COG0590@2|Bacteria	2|Bacteria	FJ	tRNA wobble adenosine to inosine editing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_163	1379698.RBG1_1C00001G1889	3.985e-14	79.0	COG2137@1|root,COG2137@2|Bacteria,2NPVT@2323|unclassified Bacteria	2|Bacteria	S	Modulates RecA activity	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496	2.4.1.337	ko:K03565,ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT4	-	RecX
SRR25158343_k127_1631683_92	1178537.BA1_00040	5.887e-66	237.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
SRR25158343_k127_1631683_122	439235.Dalk_1975	5.584e-40	162.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria,2MPGU@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158343_k127_1631683_140	491205.JARQ01000004_gene2511	1.561e-28	121.0	2CPJB@1|root,32SJ9@2|Bacteria,4PFZS@976|Bacteroidetes,1IGW3@117743|Flavobacteriia,3ZS2P@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_94	870187.Thini_3117	7.425e-65	228.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yijF	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
SRR25158343_k127_1631683_150	649638.Trad_1357	1.642e-22	106.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	PE-PPE,VKG_Carbox
SRR25158343_k127_1631683_180	864563.HMPREF9166_1435	6.489e-05	55.0	COG3307@1|root,COG3307@2|Bacteria,1V4DY@1239|Firmicutes,4H4E3@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158343_k127_1631683_66	518766.Rmar_2028	3.633e-95	347.0	COG0457@1|root,COG3829@1|root,COG0457@2|Bacteria,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1FIME@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158343_k127_1631683_1	671143.DAMO_0621	0.0	1255.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SRR25158343_k127_1631683_3	1234364.AMSF01000033_gene395	0.0	1095.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,1X351@135614|Xanthomonadales	135614|Xanthomonadales	M	in Yersinia the HmsR protein is an inner membrane protein	hmsR	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_hydro_18,Glyco_tranf_2_3,Polysacc_deac_1
SRR25158343_k127_1631683_47	251221.35211731	2.834e-122	402.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158343_k127_1631683_45	204669.Acid345_3251	1.096e-127	416.0	COG1294@1|root,COG1294@2|Bacteria,3Y3UT@57723|Acidobacteria,2JIRG@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158343_k127_1631683_24	204669.Acid345_3252	9.29e-193	612.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria,2JJ96@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158343_k127_1631683_143	502025.Hoch_5003	1.262e-26	111.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2YVP9@29|Myxococcales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158343_k127_1631683_11	404589.Anae109_0835	5.743e-281	882.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158343_k127_1631683_116	446470.Snas_0372	6.574e-46	171.0	COG4899@1|root,COG4899@2|Bacteria,2IGN5@201174|Actinobacteria,4F00Y@85014|Glycomycetales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
SRR25158343_k127_1631683_18	1340493.JNIF01000003_gene3519	9.364e-224	725.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1631683_71	886293.Sinac_4633	4.743e-91	316.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_1631683_29	1173023.KE650771_gene1929	3.544e-174	560.0	COG0654@1|root,COG0654@2|Bacteria,1G5VZ@1117|Cyanobacteria,1JII7@1189|Stigonemataceae	1117|Cyanobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158343_k127_1631683_34	861299.J421_1661	5.255e-154	499.0	COG0534@1|root,COG0534@2|Bacteria,1ZUGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158343_k127_1631683_99	765869.BDW_03405	2.571e-55	203.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2MT14@213481|Bdellovibrionales,2WMP7@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158343_k127_1631683_113	756272.Plabr_4030	6.773e-47	173.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1631683_148	1246995.AFR_18770	6.651e-24	108.0	2DQTX@1|root,32UPT@2|Bacteria,2ID1B@201174|Actinobacteria,4D8XE@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_52	1173026.Glo7428_2034	1.341e-117	388.0	COG3268@1|root,COG3268@2|Bacteria,1G3XG@1117|Cyanobacteria	1117|Cyanobacteria	S	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158343_k127_1631683_43	1191523.MROS_1166	3.594e-131	436.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158343_k127_1631683_88	429009.Adeg_1604	4.237e-74	260.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_1631683_101	204669.Acid345_2869	2.077e-54	200.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria,2JJTI@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158343_k127_1631683_136	1347368.HG964403_gene4517	2.019e-34	138.0	COG1670@1|root,COG1670@2|Bacteria,1VI3V@1239|Firmicutes,4HV5Y@91061|Bacilli,1ZS67@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158343_k127_1631683_134	1117315.AHCA01000006_gene2967	1.206e-35	142.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,2Q2D5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158343_k127_1631683_151	1116472.MGMO_141c00020	4.796e-22	101.0	2ESHS@1|root,32B3M@2|Bacteria,1P6E9@1224|Proteobacteria,1STKJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_6	1121405.dsmv_0036	6.317e-310	977.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158343_k127_1631683_120	204669.Acid345_3344	2.043e-40	163.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria,2JIK2@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SRR25158343_k127_1631683_106	204669.Acid345_0705	1.664e-48	187.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_1631683_104	398527.Bphyt_6223	1.348e-51	187.0	COG3832@1|root,COG3832@2|Bacteria,1RICZ@1224|Proteobacteria,2VTB3@28216|Betaproteobacteria,1K597@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158343_k127_1631683_149	439235.Dalk_1088	2.457e-23	111.0	COG0642@1|root,COG2202@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	2.7.13.3	ko:K02484,ko:K07645,ko:K07711	ko02020,ko02024,map02020,map02024	M00453,M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,PAS_3,PAS_8,Response_reg
SRR25158343_k127_1631683_35	67267.JNXT01000002_gene5941	2.891e-151	493.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158343_k127_1631683_174	797303.Natpe_0823	5.949e-07	63.0	COG1520@1|root,arCOG02556@2157|Archaea,2Y7Q9@28890|Euryarchaeota,240XC@183963|Halobacteria	183963|Halobacteria	C	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158343_k127_1631683_139	204669.Acid345_4448	9.803e-31	136.0	COG1595@1|root,COG1595@2|Bacteria,3Y7TB@57723|Acidobacteria,2JMZD@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158343_k127_1631683_123	1233950.IW22_07350	7.015e-40	151.0	2AWH3@1|root,31NDJ@2|Bacteria,4NRPZ@976|Bacteroidetes,1I4Y0@117743|Flavobacteriia,3ZSBB@59732|Chryseobacterium	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
SRR25158343_k127_1631683_56	1500281.JQKZ01000009_gene3066	5.04e-113	369.0	COG3361@1|root,COG3361@2|Bacteria,4NFDT@976|Bacteroidetes,1I03M@117743|Flavobacteriia,3ZR58@59732|Chryseobacterium	976|Bacteroidetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
SRR25158343_k127_1631683_82	760192.Halhy_1542	4.105e-77	267.0	COG0500@1|root,COG2226@2|Bacteria,4NGMD@976|Bacteroidetes,1IS7Q@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1631683_114	760192.Halhy_1541	2.198e-46	171.0	2AVPC@1|root,31MGE@2|Bacteria,4NQFW@976|Bacteroidetes,1IT5N@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_73	1340493.JNIF01000003_gene1300	3.242e-88	302.0	COG1073@1|root,COG1073@2|Bacteria,3Y99D@57723|Acidobacteria	57723|Acidobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF2048
SRR25158343_k127_1631683_172	1123377.AUIV01000008_gene1452	5.92e-08	63.0	2ET1X@1|root,33KK3@2|Bacteria	2|Bacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158343_k127_1631683_153	1248760.ANFZ01000009_gene1356	1.373e-21	108.0	COG3210@1|root,COG3210@2|Bacteria,1NFA7@1224|Proteobacteria,2UQTM@28211|Alphaproteobacteria,2K7A7@204457|Sphingomonadales	204457|Sphingomonadales	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158343_k127_1631683_30	1198114.AciX9_1400	1.105e-166	543.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1631683_155	399739.Pmen_0357	7.387e-20	94.0	COG2050@1|root,COG2050@2|Bacteria,1RE82@1224|Proteobacteria,1S9BW@1236|Gammaproteobacteria,1YGUG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRR25158343_k127_1631683_102	929703.KE386491_gene2143	1.659e-53	198.0	COG2755@1|root,COG2755@2|Bacteria,4NF7G@976|Bacteroidetes,47RZX@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_1631683_144	1267534.KB906760_gene1472	3.284e-26	124.0	28N30@1|root,2ZB8S@2|Bacteria,3Y2XH@57723|Acidobacteria,2JI3V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_79	204669.Acid345_4168	3.764e-83	282.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria,2JJ3P@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1631683_78	1267535.KB906767_gene897	6.116e-85	291.0	COG5002@1|root,COG5002@2|Bacteria,3Y99C@57723|Acidobacteria,2JP5N@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158343_k127_1631683_74	204669.Acid345_4171	5.136e-88	299.0	COG1398@1|root,COG1398@2|Bacteria,3Y3F9@57723|Acidobacteria,2JHWH@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158343_k127_1631683_28	1242864.D187_004920	1.446e-181	582.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158343_k127_1631683_27	1382359.JIAL01000001_gene616	5.369e-182	581.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria,2JHMR@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158343_k127_1631683_169	706587.Desti_3303	8.236e-10	63.0	COG0464@1|root,COG0464@2|Bacteria,1QFHD@1224|Proteobacteria,42QEP@68525|delta/epsilon subdivisions,2WIT4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	AAA ATPase, central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF4032
SRR25158343_k127_1631683_40	1392489.JPOL01000002_gene2135	9.635e-134	437.0	COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes	976|Bacteroidetes	I	Inositol-3-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158343_k127_1631683_22	861299.J421_4119	2.44e-195	620.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158343_k127_1631683_57	926550.CLDAP_14260	8.509e-111	368.0	COG3173@1|root,COG3173@2|Bacteria,2G5RM@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158343_k127_1631683_142	243090.RB12541	1.167e-27	127.0	COG0526@1|root,COG0526@2|Bacteria,2J35Z@203682|Planctomycetes	203682|Planctomycetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR25158343_k127_1631683_26	1295642.H839_03846	1.025e-187	593.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,1WE7R@129337|Geobacillus	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	bbsG	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_1631683_112	1144319.PMI16_04338	6.274e-47	174.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,474F3@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158343_k127_1631683_97	1268635.Loa_01727	1.338e-56	206.0	COG0596@1|root,COG0596@2|Bacteria,1QUVT@1224|Proteobacteria,1T22Q@1236|Gammaproteobacteria,1JCP7@118969|Legionellales	118969|Legionellales	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158343_k127_1631683_72	204669.Acid345_1469	3.761e-89	305.0	COG4972@1|root,COG4972@2|Bacteria,3Y804@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158343_k127_1631683_170	1304885.AUEY01000002_gene379	8.8e-10	67.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR25158343_k127_1631683_96	246197.MXAN_5772	5.61e-58	223.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158343_k127_1631683_161	1278073.MYSTI_06356	2.318e-15	80.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,2YVP4@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_31	215803.DB30_8120	4.557e-163	524.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2YUC2@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158343_k127_1631683_133	749414.SBI_05846	4.632e-36	140.0	COG0662@1|root,COG0662@2|Bacteria,2IPIR@201174|Actinobacteria	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer
SRR25158343_k127_1631683_83	469383.Cwoe_4613	2.285e-76	268.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158343_k127_1631683_44	1198114.AciX9_4589	3.749e-128	422.0	COG0438@1|root,COG0438@2|Bacteria,3Y2F3@57723|Acidobacteria,2JIQ3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1631683_131	324057.Pjdr2_1231	2.855e-37	155.0	COG0438@1|root,COG0438@2|Bacteria,1VEAG@1239|Firmicutes,4HN0E@91061|Bacilli,26TW2@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1631683_0	1144275.COCOR_03928	0.0	1664.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X7UA@28221|Deltaproteobacteria,2Z3KU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158343_k127_1631683_181	557599.MKAN_09140	7.617e-05	54.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2GNXG@201174|Actinobacteria,23296@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknD	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NHL,Pkinase
SRR25158343_k127_1631683_167	375451.RD1_B0015	3.958e-12	76.0	COG0671@1|root,COG0671@2|Bacteria,1N0QJ@1224|Proteobacteria,2UGVV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158343_k127_1631683_2	388467.A19Y_3871	0.0	1103.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158343_k127_1631683_111	1173022.Cri9333_4380	3.359e-47	179.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158343_k127_1631683_156	518766.Rmar_1142	1.959e-19	102.0	29JUY@1|root,306S8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1631683_58	880072.Desac_1327	2.826e-108	367.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2MRYR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Undecaprenyl-phosphate galactose phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158343_k127_1631683_105	1198114.AciX9_4582	1.626e-48	182.0	COG1596@1|root,COG1596@2|Bacteria,3Y591@57723|Acidobacteria,2JJVE@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158343_k127_1631683_168	1121448.DGI_1959	1.735e-10	70.0	COG0489@1|root,COG0489@2|Bacteria,1MZ64@1224|Proteobacteria,432Z4@68525|delta/epsilon subdivisions,2WXW1@28221|Deltaproteobacteria,2MDQQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	AAA domain	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31
SRR25158343_k127_1631683_95	1267535.KB906767_gene2403	3.064e-62	235.0	COG3206@1|root,COG3206@2|Bacteria,3Y4H3@57723|Acidobacteria,2JJ3W@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
SRR25158343_k127_1631683_33	227377.CBU_0503	1.581e-155	499.0	COG0174@1|root,COG0174@2|Bacteria,1NZU7@1224|Proteobacteria	1224|Proteobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158343_k127_1631683_20	929713.NIASO_15630	5.895e-207	657.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1IQY0@117747|Sphingobacteriia	976|Bacteroidetes	P	sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158343_k127_1631683_119	204669.Acid345_0534	8.336e-42	168.0	COG0738@1|root,COG0738@2|Bacteria,3Y57Y@57723|Acidobacteria,2JJQE@204432|Acidobacteriia	204432|Acidobacteriia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1631683_50	204669.Acid345_0533	6.287e-121	398.0	COG1609@1|root,COG1609@2|Bacteria,3Y6FV@57723|Acidobacteria,2JKJG@204432|Acidobacteriia	204432|Acidobacteriia	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158343_k127_1631683_8	234267.Acid_6939	5.987e-298	951.0	COG1629@1|root,COG4771@2|Bacteria,3Y2MF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1631683_81	1379270.AUXF01000001_gene2444	1.489e-77	269.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158343_k127_1631683_109	1472716.KBK24_0110000	1.273e-47	182.0	COG0627@1|root,COG0627@2|Bacteria,1NF5B@1224|Proteobacteria,2WGE5@28216|Betaproteobacteria,1KID6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158343_k127_1631683_15	485917.Phep_1292	4.678e-236	757.0	COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,1IR7F@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Malectin
SRR25158343_k127_1631683_86	485913.Krac_8838	7.167e-76	270.0	COG3875@1|root,COG3875@2|Bacteria,2G8B3@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158343_k127_1631683_14	469383.Cwoe_5411	1.367e-253	823.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158343_k127_1631683_23	697281.Mahau_2368	3.054e-195	621.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42ESS@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system	xylG	-	3.6.3.17	ko:K10441,ko:K10545	ko02010,map02010	M00212,M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4	-	-	ABC_tran
SRR25158343_k127_1631683_55	204669.Acid345_0905	2.315e-113	377.0	COG4214@1|root,COG4214@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR25158343_k127_1631683_69	1254432.SCE1572_35695	3.103e-93	317.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,4306C@68525|delta/epsilon subdivisions,2WVFZ@28221|Deltaproteobacteria,2YU0U@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein domain	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158343_k127_1631683_12	1123073.KB899241_gene2308	1.26e-266	844.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,1X3WR@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SRR25158343_k127_1631683_4	1173026.Glo7428_0932	0.0	1015.0	COG1216@1|root,COG5309@1|root,COG1216@2|Bacteria,COG5309@2|Bacteria,1G2MT@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
SRR25158343_k127_1631683_68	489825.LYNGBM3L_21210	1.885e-93	322.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1642801_94	1296416.JACB01000001_gene3282	8.959e-15	89.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia,2YKBW@290174|Aquimarina	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
SRR25158343_k127_1642801_78	1041826.FCOL_08560	1.821e-21	99.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2NUMJ@237|Flavobacterium	976|Bacteroidetes	EU	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
SRR25158343_k127_1642801_64	864702.OsccyDRAFT_4305	1.74e-34	149.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1H8JB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3471,PD40,Peptidase_S9,Peptidase_S9_N
SRR25158343_k127_1642801_35	765914.ThisiDRAFT_1706	2.293e-59	217.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1WW3B@135613|Chromatiales	135613|Chromatiales	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
SRR25158343_k127_1642801_24	163908.KB235896_gene2700	6.367e-85	291.0	COG2253@1|root,COG2253@2|Bacteria,1GBWG@1117|Cyanobacteria,1HQV5@1161|Nostocales	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158343_k127_1642801_46	360094.PXO_01414	5.508e-52	190.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,1RN7A@1236|Gammaproteobacteria,1X7AV@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158343_k127_1642801_90	452638.Pnec_1608	4.277e-17	86.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1K2Q6@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158343_k127_1642801_83	1121396.KB893055_gene2591	1.939e-20	97.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2MK10@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158343_k127_1642801_87	1121918.ARWE01000001_gene2862	2.625e-18	94.0	COG0258@1|root,COG0328@1|root,COG0258@2|Bacteria,COG0328@2|Bacteria,1NRSF@1224|Proteobacteria,42YWE@68525|delta/epsilon subdivisions,2WTRZ@28221|Deltaproteobacteria,43SWB@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	5_3_exonuc,5_3_exonuc_N,RNase_H
SRR25158343_k127_1642801_109	189753.AXAS01000004_gene1017	0.0001594	55.0	COG3843@1|root,COG3843@2|Bacteria,1MU0S@1224|Proteobacteria,2TSP8@28211|Alphaproteobacteria,3JSRJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Protein of unknown function (DUF3363)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3363
SRR25158343_k127_1642801_10	1382359.JIAL01000001_gene270	2.012e-122	405.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158343_k127_1642801_79	521460.Athe_2519	2.36e-21	110.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,42ERK@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM TRAG family protein	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
SRR25158343_k127_1642801_92	1385521.N803_11015	1.646e-16	91.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4FFW7@85021|Intrasporangiaceae	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158343_k127_1642801_67	754035.Mesau_06002	2.144e-33	135.0	COG3703@1|root,COG3703@2|Bacteria,1NRIR@1224|Proteobacteria,2UPT4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
SRR25158343_k127_1642801_30	251229.Chro_4000	1.078e-65	231.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158343_k127_1642801_63	195253.Syn6312_2763	9.997e-35	138.0	COG1974@1|root,COG1974@2|Bacteria,1G6T1@1117|Cyanobacteria,1H08K@1129|Synechococcus	1117|Cyanobacteria	L	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158343_k127_1642801_14	1121448.DGI_0475	1.349e-109	369.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NJ4@68525|delta/epsilon subdivisions,2WJXN@28221|Deltaproteobacteria,2M84T@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	umuC	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
SRR25158343_k127_1642801_84	349106.PsycPRwf_1871	2.396e-20	103.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S28H@1236|Gammaproteobacteria,3NJTE@468|Moraxellaceae	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158343_k127_1642801_86	1382359.JIAL01000001_gene292	1.979e-19	104.0	COG3451@1|root,COG3451@2|Bacteria,3Y70M@57723|Acidobacteria,2JKY3@204432|Acidobacteriia	204432|Acidobacteriia	U	type IV secretory pathway VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_105	1235457.C404_05735	8.977e-07	53.0	COG3291@1|root,COG3291@2|Bacteria,1R9R7@1224|Proteobacteria,2VUZS@28216|Betaproteobacteria,1K6JB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_0	204669.Acid345_1624	0.0	1231.0	COG4447@1|root,COG4447@2|Bacteria,3Y2SN@57723|Acidobacteria,2JIF7@204432|Acidobacteriia	204432|Acidobacteriia	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158343_k127_1642801_27	306281.AJLK01000073_gene2547	3.883e-70	245.0	COG4188@1|root,COG4188@2|Bacteria,1GD7B@1117|Cyanobacteria	1117|Cyanobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SRR25158343_k127_1642801_103	1183438.GKIL_0502	5.735e-08	55.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,PAF-AH_p_II
SRR25158343_k127_1642801_97	1469607.KK073768_gene323	8.294e-12	65.0	COG3293@1|root,336M0@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
SRR25158343_k127_1642801_101	118173.KB235913_gene4323	3.268e-10	66.0	COG1234@1|root,COG1234@2|Bacteria,1G1SW@1117|Cyanobacteria,1HATW@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR25158343_k127_1642801_56	1469607.KK073765_gene6469	5.272e-40	153.0	COG1234@1|root,COG1234@2|Bacteria,1G1SW@1117|Cyanobacteria,1HTPW@1161|Nostocales	1117|Cyanobacteria	L	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR25158343_k127_1642801_17	204669.Acid345_4339	3.303e-101	339.0	COG2855@1|root,COG2855@2|Bacteria,3Y3R4@57723|Acidobacteria,2JHTG@204432|Acidobacteriia	204432|Acidobacteriia	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
SRR25158343_k127_1642801_57	204669.Acid345_2687	1.284e-39	154.0	COG5553@1|root,COG5553@2|Bacteria,3Y975@57723|Acidobacteria,2JNQM@204432|Acidobacteriia	204432|Acidobacteriia	S	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
SRR25158343_k127_1642801_19	234267.Acid_6667	5.936e-91	308.0	COG0583@1|root,COG0583@2|Bacteria,3Y4AE@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158343_k127_1642801_3	886293.Sinac_0625	2.064e-235	758.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	2|Bacteria	S	PFAM Peptidase M16 inactive domain	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1642801_41	472759.Nhal_2145	1.749e-54	198.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria,1WYS2@135613|Chromatiales	135613|Chromatiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158343_k127_1642801_9	278963.ATWD01000001_gene2473	2.93e-149	497.0	COG4232@1|root,COG4232@2|Bacteria,3Y771@57723|Acidobacteria	57723|Acidobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD,Thioredoxin_7
SRR25158343_k127_1642801_85	694427.Palpr_2526	1.653e-19	101.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia,22XR2@171551|Porphyromonadaceae	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
SRR25158343_k127_1642801_69	234267.Acid_0091	5.736e-32	139.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158343_k127_1642801_36	234267.Acid_0090	3.647e-58	224.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrA	-	1.1.98.6,1.8.1.9,1.8.4.11,1.8.4.12	ko:K00384,ko:K12057,ko:K12267,ko:K21636	ko00230,ko00240,ko00450,ko01100,map00230,map00240,map00450,map01100	M00053	R02016,R03596,R09372,R11633,R11634,R11635,R11636	RC00013,RC00613,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.7.11.1	-	-	AhpC-TSA,PMSR,Pyr_redox_2,SelR,Thioredoxin,Thioredoxin_3,Thioredoxin_7,TraF
SRR25158343_k127_1642801_6	1340493.JNIF01000003_gene3421	2.222e-212	699.0	COG1629@1|root,COG1629@2|Bacteria,3Y67H@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_1642801_68	234267.Acid_0138	2.922e-32	145.0	COG3806@1|root,COG3806@2|Bacteria,3Y5HQ@57723|Acidobacteria	57723|Acidobacteria	T	Anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_75	234267.Acid_0137	4.986e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,3Y5ME@57723|Acidobacteria	57723|Acidobacteria	K	region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_1642801_13	313624.NSP_12570	5.129e-113	387.0	COG4178@1|root,COG4178@2|Bacteria,1G1HI@1117|Cyanobacteria,1HMHV@1161|Nostocales	1117|Cyanobacteria	S	ABC transporter	-	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
SRR25158343_k127_1642801_12	13035.Dacsa_3072	1.447e-116	396.0	COG4178@1|root,COG4178@2|Bacteria,1G1HI@1117|Cyanobacteria	1117|Cyanobacteria	S	ABC transporter	-	-	-	ko:K02021,ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.203.11,3.A.1.203.4,3.A.1.21	-	-	ABC_membrane_2,ABC_tran
SRR25158343_k127_1642801_76	1346330.M472_09650	5.736e-24	119.0	COG0526@1|root,COG0526@2|Bacteria,4NI7U@976|Bacteroidetes,1IPS3@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158343_k127_1642801_1	1121481.AUAS01000001_gene4718	7.742e-308	968.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47K02@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1642801_4	1340493.JNIF01000003_gene3421	3.033e-233	758.0	COG1629@1|root,COG1629@2|Bacteria,3Y67H@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_1642801_88	536227.CcarbDRAFT_0115	9.644e-18	94.0	COG1725@1|root,COG1725@2|Bacteria,1UI02@1239|Firmicutes,25E8R@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K07978	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158343_k127_1642801_77	1122194.AUHU01000005_gene996	3.355e-23	111.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG4974 Site-specific recombinase XerD	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158343_k127_1642801_81	264732.Moth_0358	1.122e-20	105.0	COG0358@1|root,COG0358@2|Bacteria,1UYVG@1239|Firmicutes,24GCV@186801|Clostridia,42G8Y@68295|Thermoanaerobacterales	186801|Clostridia	L	Domain of unknown function (DUF3854)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3854,zf-CHC2
SRR25158343_k127_1642801_95	926554.KI912677_gene2465	9.057e-15	82.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	yhjQ	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CBP_BcsQ,CbiA
SRR25158343_k127_1642801_55	1123288.SOV_4c02780	3.993e-40	162.0	COG0503@1|root,COG0553@1|root,COG2263@1|root,COG3846@1|root,COG0503@2|Bacteria,COG0553@2|Bacteria,COG2263@2|Bacteria,COG3846@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes	909932|Negativicutes	F	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158343_k127_1642801_8	4558.Sb06g028060.1	2.775e-157	537.0	KOG1513@1|root,KOG1513@2759|Eukaryota,37NG7@33090|Viridiplantae,3GCMS@35493|Streptophyta,3KNC8@4447|Liliopsida,3I81U@38820|Poales	35493|Streptophyta	KT	Protein strawberry notch	-	GO:0002009,GO:0002165,GO:0003002,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006355,GO:0006357,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007275,GO:0007389,GO:0007444,GO:0007447,GO:0007450,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008587,GO:0009266,GO:0009408,GO:0009628,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009953,GO:0009987,GO:0010286,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016584,GO:0019219,GO:0019222,GO:0022607,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031490,GO:0031497,GO:0032501,GO:0032502,GO:0034622,GO:0034728,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035222,GO:0035239,GO:0035295,GO:0040029,GO:0042393,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0048190,GO:0048513,GO:0048518,GO:0048522,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051276,GO:0051716,GO:0060255,GO:0060429,GO:0060562,GO:0065003,GO:0065004,GO:0065007,GO:0071103,GO:0071824,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:1900034,GO:1900036,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990841,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AAA_34,Helicase_C_4,PHD
SRR25158343_k127_1642801_31	1304872.JAGC01000009_gene1436	4.983e-63	230.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2M91P@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158343_k127_1642801_106	1183438.GKIL_1744	8.17e-06	51.0	2EFI4@1|root,339AK@2|Bacteria,1G9KJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_99	1469607.KK073765_gene6567	1.346e-10	71.0	2EANP@1|root,33TNY@2|Bacteria,1GK24@1117|Cyanobacteria,1HRCV@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_72	211165.AJLN01000015_gene2250	3.262e-27	119.0	2E1Q3@1|root,33RQ1@2|Bacteria,1GBXH@1117|Cyanobacteria,1JJVD@1189|Stigonemataceae	1117|Cyanobacteria	S	Prokaryotic E2 family D	-	-	-	-	-	-	-	-	-	-	-	-	Prok-E2_D
SRR25158343_k127_1642801_71	163908.KB235896_gene4912	6.762e-28	123.0	2BTXN@1|root,32P5U@2|Bacteria,1GHX5@1117|Cyanobacteria,1HRAB@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_42	927677.ALVU02000002_gene310	3.531e-54	201.0	COG0476@1|root,COG0476@2|Bacteria,1G5NY@1117|Cyanobacteria	1117|Cyanobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158343_k127_1642801_89	56107.Cylst_5239	2.315e-17	86.0	COG4646@1|root,COG4646@2|Bacteria,1GFRE@1117|Cyanobacteria	1117|Cyanobacteria	KL	Protein of unknown function (DUF2958)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2958
SRR25158343_k127_1642801_22	869209.Tresu_2629	6.966e-87	308.0	COG0464@1|root,COG0464@2|Bacteria,2J6T3@203691|Spirochaetes	203691|Spirochaetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158343_k127_1642801_73	1408437.JNJN01000016_gene512	6.38e-27	118.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,25W8H@186806|Eubacteriaceae	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158343_k127_1642801_47	28072.Nos7524_0983	9.481e-52	190.0	2BDHM@1|root,3276T@2|Bacteria,1G751@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_2	118168.MC7420_1255	1.039e-289	923.0	COG1002@1|root,COG1002@2|Bacteria,1G3V8@1117|Cyanobacteria,1H96M@1150|Oscillatoriales	1117|Cyanobacteria	L	COG1002 Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158343_k127_1642801_96	1047013.AQSP01000137_gene547	5.177e-12	78.0	COG0582@1|root,COG0582@2|Bacteria,2NRA8@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158343_k127_1642801_66	1031288.AXAA01000048_gene776	1.97e-33	151.0	COG3941@1|root,COG3941@2|Bacteria,1V33U@1239|Firmicutes,25JFK@186801|Clostridia,36M33@31979|Clostridiaceae	186801|Clostridia	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_26	1123277.KB893229_gene1930	6.797e-74	259.0	COG0358@1|root,COG0358@2|Bacteria,4NEFU@976|Bacteroidetes,47Q6Q@768503|Cytophagia	976|Bacteroidetes	L	COG NOG08810 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_11	1266925.JHVX01000006_gene2203	3.294e-122	413.0	COG5519@1|root,COG5519@2|Bacteria,1MW5H@1224|Proteobacteria,2VHZ7@28216|Betaproteobacteria,3732W@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Domain of unknown function (DUF927)	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	DUF927,PriCT_2,Toprim_3
SRR25158343_k127_1642801_65	1267533.KB906734_gene3683	1.109e-33	143.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158343_k127_1642801_60	246197.MXAN_0236	1.217e-38	159.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2YUS5@29|Myxococcales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158343_k127_1642801_29	1177154.Y5S_03342	4.459e-68	246.0	28KY1@1|root,2ZADS@2|Bacteria,1R4MP@1224|Proteobacteria,1RPYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_5	640511.BC1002_6472	1.583e-229	769.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,Response_reg
SRR25158343_k127_1642801_39	1122947.FR7_3924	9.977e-55	200.0	COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,4H2KJ@909932|Negativicutes	909932|Negativicutes	T	PFAM response regulator receiver, regulatory protein LuxR	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158343_k127_1642801_82	1121459.AQXE01000001_gene2852	1.459e-20	98.0	COG2199@1|root,COG2199@2|Bacteria,1R4NY@1224|Proteobacteria,43AEW@68525|delta/epsilon subdivisions,2WPD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
SRR25158343_k127_1642801_80	1038859.AXAU01000003_gene5960	3.019e-21	96.0	2F35P@1|root,33W0B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_62	1382359.JIAL01000001_gene1190	7.354e-37	147.0	2DN69@1|root,32VSI@2|Bacteria,3Y8AJ@57723|Acidobacteria,2JN5W@204432|Acidobacteriia	204432|Acidobacteriia	S	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
SRR25158343_k127_1642801_32	572546.Arcpr_0656	2.254e-62	234.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,245XG@183980|Archaeoglobi	183980|Archaeoglobi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158343_k127_1642801_40	1184267.A11Q_2332	1.302e-54	203.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2MUQI@213481|Bdellovibrionales,2WM7E@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	PFAM NAD-dependent epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
SRR25158343_k127_1642801_50	324602.Caur_1283	1.004e-48	188.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1642801_108	316067.Geob_2963	5.744e-05	55.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR25158343_k127_1642801_98	666685.R2APBS1_0223	8.549e-11	74.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1SG73@1236|Gammaproteobacteria,1X5NU@135614|Xanthomonadales	135614|Xanthomonadales	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,He_PIG
SRR25158343_k127_1642801_28	243164.DET1208	1.005e-69	249.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,34CN9@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158343_k127_1642801_23	1198232.CYCME_1442	8.358e-86	296.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158343_k127_1642801_33	1198232.CYCME_1452	7.703e-62	226.0	COG0673@1|root,COG0673@2|Bacteria,1R8B2@1224|Proteobacteria	1224|Proteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158343_k127_1642801_49	1198232.CYCME_1448	5.643e-49	186.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1642801_74	247490.KSU1_C1619	3.239e-26	122.0	COG1216@1|root,COG1216@2|Bacteria,2J0NC@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1642801_43	886293.Sinac_2707	2.138e-53	200.0	COG1215@1|root,COG1215@2|Bacteria,2J0YZ@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1642801_58	886293.Sinac_2707	3.403e-39	161.0	COG1215@1|root,COG1215@2|Bacteria,2J0YZ@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1642801_100	686578.AFFX01000015_gene1879	1.785e-10	68.0	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	ybcI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158343_k127_1642801_18	886293.Sinac_6605	4.379e-92	316.0	COG0438@1|root,COG0438@2|Bacteria,2J0HS@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1642801_15	886293.Sinac_6604	2.377e-107	362.0	COG0438@1|root,COG0438@2|Bacteria,2J2E7@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1642801_61	1121430.JMLG01000009_gene432	1.56e-38	156.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,261SN@186807|Peptococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158343_k127_1642801_52	1232410.KI421412_gene247	2.812e-46	181.0	COG0535@1|root,COG0535@2|Bacteria,1RADC@1224|Proteobacteria,42RDA@68525|delta/epsilon subdivisions,2WN4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
SRR25158343_k127_1642801_48	886293.Sinac_6608	9.887e-51	193.0	COG0500@1|root,COG2226@2|Bacteria,2J1F4@203682|Planctomycetes	203682|Planctomycetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1642801_21	1198232.CYCME_1447	1.178e-87	301.0	COG1216@1|root,COG1216@2|Bacteria,1RHVX@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1642801_70	316067.Geob_1222	2.122e-28	131.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_1642801_107	716544.wcw_0648	3.435e-05	52.0	2ENCP@1|root,33G06@2|Bacteria,2JHC7@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_7	402777.KB235903_gene853	7.57e-167	539.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158343_k127_1642801_104	1198232.CYCME_1453	5.211e-07	57.0	COG1232@1|root,COG1232@2|Bacteria,1QX3T@1224|Proteobacteria,1T3RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158343_k127_1642801_34	83406.HDN1F_22600	1.344e-61	227.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158343_k127_1642801_59	929506.CbC4_1012	6.866e-39	162.0	COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,24AD0@186801|Clostridia,36EMQ@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158343_k127_1642801_54	1121438.JNJA01000001_gene2116	3.248e-40	163.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2XA3V@28221|Deltaproteobacteria,2MCM8@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158343_k127_1642801_91	1168289.AJKI01000021_gene1727	4.99e-17	92.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,2FMI3@200643|Bacteroidia,3XITB@558415|Marinilabiliaceae	976|Bacteroidetes	Q	Mycolic acid cyclopropane synthetase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158343_k127_1642801_102	314266.SKA58_00005	1.957e-09	72.0	2C9DE@1|root,2Z8R4@2|Bacteria,1NVMQ@1224|Proteobacteria,2U51M@28211|Alphaproteobacteria,2K0UF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_16	1122138.AQUZ01000002_gene1954	3.351e-104	355.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4DTW1@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158343_k127_1642801_38	448385.sce7282	1.573e-55	211.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce7282|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_25	56107.Cylst_0473	1.535e-81	289.0	COG2215@1|root,COG2215@2|Bacteria,1G36H@1117|Cyanobacteria,1HQQ3@1161|Nostocales	1117|Cyanobacteria	S	High-affinity nickel-transport protein	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	DsbD_2,NicO
SRR25158343_k127_1642801_51	1049564.TevJSym_aa02470	1.513e-47	179.0	COG2215@1|root,COG2215@2|Bacteria,1R3QK@1224|Proteobacteria,1SARN@1236|Gammaproteobacteria,1JB4F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2,NicO
SRR25158343_k127_1642801_45	1173026.Glo7428_3224	2.19e-52	194.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria	1117|Cyanobacteria	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRR25158343_k127_1642801_44	1123508.JH636456_gene135	3.025e-53	196.0	COG2197@1|root,COG2197@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_1642801_53	1123242.JH636435_gene1488	1.935e-41	175.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HWE_HK,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3,STAS
SRR25158343_k127_1642801_37	313612.L8106_00900	6.51e-56	221.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2461@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158343_k127_1642801_93	1283284.AZUK01000001_gene1475	2.5e-15	87.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1Y3XQ@135624|Aeromonadales	135624|Aeromonadales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158343_k127_1642801_110	1122621.ATZA01000016_gene3727	0.0007209	48.0	293N5@1|root,2ZR3X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1642801_20	1304877.KI519399_gene2284	1.251e-88	302.0	COG0476@1|root,COG0476@2|Bacteria,1NFVV@1224|Proteobacteria,2TV6X@28211|Alphaproteobacteria,3K1XY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158343_k127_1681888_32	211165.AJLN01000066_gene4484	3.014e-22	99.0	COG3668@1|root,COG3668@2|Bacteria,1G8E5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Plasmid stabilisation system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158343_k127_1681888_34	1469607.KK073768_gene2753	1.87e-18	87.0	COG3609@1|root,COG3609@2|Bacteria,1GKND@1117|Cyanobacteria,1HTC6@1161|Nostocales	1117|Cyanobacteria	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
SRR25158343_k127_1681888_46	1120951.AUBG01000012_gene1660	2.293e-06	52.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158343_k127_1681888_43	485918.Cpin_6628	9.876e-08	66.0	2DP40@1|root,330F7@2|Bacteria,4NV4R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1681888_38	1353529.M899_2680	1.615e-12	82.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158343_k127_1681888_40	1536769.P40081_27470	3.332e-11	68.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
SRR25158343_k127_1681888_22	1250006.JHZZ01000001_gene1379	1.541e-65	256.0	COG0433@1|root,COG0433@2|Bacteria,4NVJM@976|Bacteroidetes,1I7IY@117743|Flavobacteriia,3VX4H@52959|Polaribacter	976|Bacteroidetes	S	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR25158343_k127_1681888_45	1565314.OA34_00075	1.734e-06	56.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2YNW3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158343_k127_1681888_14	391626.OAN307_c31540	1.354e-105	362.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1681888_30	1211777.BN77_p2150094	5.988e-26	123.0	COG0476@1|root,COG0476@2|Bacteria,1NPTG@1224|Proteobacteria,2UNBV@28211|Alphaproteobacteria,4BIPZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Prokaryotic E2 family C	-	-	-	-	-	-	-	-	-	-	-	-	Prok-E2_C,ThiF
SRR25158343_k127_1681888_35	1040982.AXAL01000005_gene3773	1.077e-14	80.0	2B8CA@1|root,337AS@2|Bacteria,1R3C7@1224|Proteobacteria,2U00A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158343_k127_1681888_48	1245469.S58_71780	7.111e-05	51.0	2C1UN@1|root,33WG6@2|Bacteria,1RM5V@1224|Proteobacteria,2UA1P@28211|Alphaproteobacteria,3K0HE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Predicted metal binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Metal_CEHH
SRR25158343_k127_1681888_44	1499680.CCFE01000010_gene87	1.342e-06	55.0	COG1476@1|root,COG1476@2|Bacteria,1UBUG@1239|Firmicutes,4IN9Y@91061|Bacilli,1ZN45@1386|Bacillus	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158343_k127_1681888_31	1196031.ALEG01000012_gene736	1.005e-25	113.0	COG2856@1|root,COG2856@2|Bacteria,1UKQW@1239|Firmicutes	1239|Firmicutes	K	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158343_k127_1681888_16	391626.OAN307_c31540	1.793e-97	332.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_1681888_25	375286.mma_2730	9.76e-51	184.0	arCOG06889@1|root,32RJ7@2|Bacteria,1N0UJ@1224|Proteobacteria,2VQ2T@28216|Betaproteobacteria,477Z7@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158343_k127_1681888_6	1392490.JHZX01000001_gene3018	1.078e-173	557.0	COG0846@1|root,COG0846@2|Bacteria,4NN8D@976|Bacteroidetes,1I1IA@117743|Flavobacteriia	976|Bacteroidetes	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
SRR25158343_k127_1681888_28	1121897.AUGO01000011_gene3150	1.829e-30	127.0	2DIKB@1|root,32UB7@2|Bacteria,4NQYE@976|Bacteroidetes,1I4B0@117743|Flavobacteriia,2NX4V@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158343_k127_1681888_23	257310.BB0482	3.024e-63	222.0	arCOG06889@1|root,32RJ7@2|Bacteria,1N0UJ@1224|Proteobacteria,2VXIV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158343_k127_1681888_50	1121090.KB894686_gene2991	0.0002787	48.0	COG1522@1|root,COG1522@2|Bacteria,1VVNW@1239|Firmicutes,4HWH8@91061|Bacilli,1ZFTW@1386|Bacillus	91061|Bacilli	K	sequence-specific DNA binding	xkdB	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1681888_11	402881.Plav_0314	2.46e-128	422.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,2U47U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
SRR25158343_k127_1681888_18	234267.Acid_2524	6.951e-81	280.0	2E0FE@1|root,32W1M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
SRR25158343_k127_1681888_49	1278073.MYSTI_04242	0.0001591	47.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	stk1	-	2.7.11.1	ko:K08282,ko:K11916,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko02044	-	-	-	DUF4384,FGE-sulfatase,Pkinase
SRR25158343_k127_1681888_27	1469607.KK073768_gene4395	4.021e-34	135.0	COG4113@1|root,COG4113@2|Bacteria,1G6NY@1117|Cyanobacteria,1HPH0@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158343_k127_1681888_47	1173028.ANKO01000164_gene2738	2.164e-05	49.0	2DSE5@1|root,33FS0@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
SRR25158343_k127_1681888_26	926566.Terro_2824	2.076e-36	149.0	COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria,2JKNX@204432|Acidobacteriia	204432|Acidobacteriia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR25158343_k127_1681888_15	639030.JHVA01000001_gene601	1.342e-98	332.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158343_k127_1681888_1	234267.Acid_0200	4.095e-281	885.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1681888_3	1267535.KB906767_gene1540	2.25e-232	756.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_1681888_39	388413.ALPR1_17993	2.85e-11	75.0	COG0329@1|root,COG0329@2|Bacteria,4NFIH@976|Bacteroidetes	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
SRR25158343_k127_1681888_10	234267.Acid_2658	2.284e-130	428.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2
SRR25158343_k127_1681888_4	1027273.GZ77_25715	2.756e-184	593.0	COG1069@1|root,COG1069@2|Bacteria,1MY11@1224|Proteobacteria,1RP3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the ribulokinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
SRR25158343_k127_1681888_2	1123242.JH636435_gene2020	2.636e-247	772.0	COG2407@1|root,COG2407@2|Bacteria,2IXT8@203682|Planctomycetes	203682|Planctomycetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1681888_13	497964.CfE428DRAFT_3513	3.312e-111	364.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158343_k127_1681888_17	497964.CfE428DRAFT_3511	3.305e-89	301.0	COG3836@1|root,COG3836@2|Bacteria,46V5P@74201|Verrucomicrobia	74201|Verrucomicrobia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158343_k127_1681888_7	234267.Acid_7032	3.187e-162	522.0	COG2271@1|root,COG2271@2|Bacteria,3Y3FW@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1681888_5	234267.Acid_2416	4.276e-178	570.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
SRR25158343_k127_1681888_9	1267535.KB906767_gene4826	2.458e-148	478.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,3Y2MP@57723|Acidobacteria,2JM00@204432|Acidobacteriia	204432|Acidobacteriia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158343_k127_1681888_21	204669.Acid345_1043	8.429e-68	248.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria,2JID2@204432|Acidobacteriia	204432|Acidobacteriia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158343_k127_1681888_12	1163617.SCD_n00323	3.822e-121	397.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2WGFK@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158343_k127_1681888_20	13035.Dacsa_1888	9.003e-75	257.0	COG0637@1|root,COG0637@2|Bacteria,1G6EG@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
SRR25158343_k127_1681888_41	926566.Terro_2875	1.86e-09	72.0	2C9DE@1|root,2Z8R4@2|Bacteria,3Y3TP@57723|Acidobacteria,2JISK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1681888_24	251221.35211166	1.051e-54	209.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SRR25158343_k127_1681888_37	429009.Adeg_0825	1.126e-12	80.0	2DU2I@1|root,33NNN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1681888_36	471223.GWCH70_3123	1.253e-13	84.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1WF2M@129337|Geobacillus	91061|Bacilli	M	Subtilase family	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,SLH
SRR25158343_k127_1681888_19	861299.J421_5966	3.244e-75	289.0	COG1112@1|root,COG1112@2|Bacteria	2|Bacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,DUF3320,DUF4011,DUF559,GreA_GreB
SRR25158343_k127_1681888_0	861299.J421_5967	0.0	1243.0	COG1112@1|root,COG1112@2|Bacteria	2|Bacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,DUF3320,DUF4011,DUF559,GreA_GreB
SRR25158343_k127_1681888_29	1128421.JAGA01000003_gene2851	4.059e-26	117.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DUF2779,PDDEXK_1
SRR25158343_k127_1681888_33	313606.M23134_06412	4.297e-20	91.0	COG3587@1|root,COG3587@2|Bacteria,4NGM0@976|Bacteroidetes,47NJ5@768503|Cytophagia	976|Bacteroidetes	V	Type III restriction enzyme, res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
SRR25158343_k127_1683103_148	1499967.BAYZ01000075_gene2072	1.502e-05	48.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158343_k127_1683103_126	56780.SYN_01756	1.655e-17	97.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria	1224|Proteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
SRR25158343_k127_1683103_153	398767.Glov_2153	0.0002749	50.0	COG4967@1|root,COG4967@2|Bacteria,1NHY3@1224|Proteobacteria,42WZH@68525|delta/epsilon subdivisions,2WSKR@28221|Deltaproteobacteria,43VUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	pilV-2	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SRR25158343_k127_1683103_154	1232437.KL662002_gene4686	0.0004495	50.0	COG4966@1|root,COG4966@2|Bacteria,1Q8WF@1224|Proteobacteria,4342J@68525|delta/epsilon subdivisions,2X4VM@28221|Deltaproteobacteria,2MM37@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SRR25158343_k127_1683103_138	1158150.KB906241_gene999	1.636e-09	71.0	COG4726@1|root,COG4726@2|Bacteria,1NK1B@1224|Proteobacteria,1SGXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
SRR25158343_k127_1683103_124	1122247.C731_2943	4.843e-20	93.0	COG1694@1|root,COG1694@2|Bacteria,2INKJ@201174|Actinobacteria	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158343_k127_1683103_51	1121468.AUBR01000010_gene2431	6.264e-103	355.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158343_k127_1683103_121	1410670.JHXF01000007_gene662	2.882e-22	101.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WK7G@541000|Ruminococcaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158343_k127_1683103_99	1230342.CTM_21301	4.715e-41	158.0	COG3034@1|root,COG3034@2|Bacteria,1VDHB@1239|Firmicutes,24DG5@186801|Clostridia,36HZJ@31979|Clostridiaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158343_k127_1683103_20	929562.Emtol_0548	2.621e-157	505.0	COG1914@1|root,COG1914@2|Bacteria,4NH9R@976|Bacteroidetes,47NVB@768503|Cytophagia	976|Bacteroidetes	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRR25158343_k127_1683103_53	929562.Emtol_0422	2.765e-99	329.0	COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,47JP6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158343_k127_1683103_68	700598.Niako_1615	1.77e-76	267.0	COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1IQAT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Allophanate hydrolase subunit 2	-	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
SRR25158343_k127_1683103_76	224308.BSU04080	9.61e-66	233.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,1ZDVS@1386|Bacillus	91061|Bacilli	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
SRR25158343_k127_1683103_81	1033737.CAEV01000022_gene3286	8.129e-62	225.0	COG1131@1|root,COG1131@2|Bacteria,1UHTY@1239|Firmicutes,24JZH@186801|Clostridia,36UHX@31979|Clostridiaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158343_k127_1683103_18	43989.cce_2032	4.556e-163	553.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGMH@43988|Cyanothece	1117|Cyanobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
SRR25158343_k127_1683103_58	639030.JHVA01000001_gene3875	1.669e-94	317.0	COG1173@1|root,COG1173@2|Bacteria,3Y45P@57723|Acidobacteria,2JIKH@204432|Acidobacteriia	204432|Acidobacteriia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158343_k127_1683103_59	1382359.JIAL01000001_gene2582	9.264e-88	300.0	COG0601@1|root,COG0601@2|Bacteria,3Y437@57723|Acidobacteria,2JHY6@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158343_k127_1683103_75	234267.Acid_7345	1.134e-66	235.0	COG0500@1|root,COG2226@2|Bacteria,3Y44I@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158343_k127_1683103_137	1038860.AXAP01000013_gene1183	8.173e-11	74.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2TRMX@28211|Alphaproteobacteria,3JSBY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Peptidase M16 inactive domain	pqqG	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1683103_135	1382359.JIAL01000001_gene2600	9.695e-13	80.0	COG0810@1|root,COG0810@2|Bacteria,3Y58J@57723|Acidobacteria,2JJPH@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158343_k127_1683103_88	1297742.A176_07019	4.291e-53	205.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SRR25158343_k127_1683103_42	525904.Tter_2339	2.155e-121	403.0	COG1914@1|root,COG1914@2|Bacteria,2NNYP@2323|unclassified Bacteria	2|Bacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
SRR25158343_k127_1683103_90	243231.GSU2316	5.183e-52	195.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,43S51@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
SRR25158343_k127_1683103_0	497964.CfE428DRAFT_1607	0.0	1254.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158343_k127_1683103_44	1521187.JPIM01000068_gene757	6.044e-118	389.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158343_k127_1683103_66	525904.Tter_2460	6.673e-78	268.0	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	agaR	-	-	ko:K02081,ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158343_k127_1683103_25	525904.Tter_2204	1.287e-146	473.0	COG1085@1|root,COG1085@2|Bacteria,2NQA3@2323|unclassified Bacteria	2|Bacteria	H	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
SRR25158343_k127_1683103_43	765420.OSCT_1871	1.204e-118	391.0	COG0483@1|root,COG0483@2|Bacteria,2G88V@200795|Chloroflexi	200795|Chloroflexi	G	inositol monophosphate 1-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_33	525904.Tter_2202	1.686e-135	446.0	COG0153@1|root,COG0153@2|Bacteria,2NQRK@2323|unclassified Bacteria	2|Bacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158343_k127_1683103_45	930946.AEOP01000018_gene1218	1.205e-116	384.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,4AX2H@81850|Leuconostocaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158343_k127_1683103_13	204669.Acid345_0903	1.059e-181	575.0	COG2115@1|root,COG2115@2|Bacteria,3Y841@57723|Acidobacteria,2JNHR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the xylose isomerase family	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158343_k127_1683103_11	204669.Acid345_0904	9.625e-186	592.0	COG1070@1|root,COG1070@2|Bacteria,3Y2V6@57723|Acidobacteria,2JJ35@204432|Acidobacteriia	204432|Acidobacteriia	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158343_k127_1683103_32	762903.Pedsa_0636	6.929e-137	443.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,1IRGT@117747|Sphingobacteriia	976|Bacteroidetes	C	galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRR25158343_k127_1683103_24	384765.SIAM614_30241	1.83e-147	483.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter	alsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158343_k127_1683103_35	1396141.BATP01000038_gene1207	2.041e-128	417.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158343_k127_1683103_91	1382359.JIAL01000001_gene235	7.504e-52	191.0	COG0664@1|root,COG0664@2|Bacteria,3Y4WU@57723|Acidobacteria,2JMTC@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_1683103_94	357808.RoseRS_4462	7.058e-46	176.0	294HY@1|root,2ZRXK@2|Bacteria,2GAIJ@200795|Chloroflexi,376D9@32061|Chloroflexia	32061|Chloroflexia	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158343_k127_1683103_89	204669.Acid345_0365	4.818e-52	193.0	COG2846@1|root,COG2846@2|Bacteria,3Y4SU@57723|Acidobacteria,2JMU3@204432|Acidobacteriia	204432|Acidobacteriia	D	Domain of Unknown function (DUF542)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SRR25158343_k127_1683103_1	1210884.HG799463_gene9843	7.007e-307	956.0	COG3256@1|root,COG3256@2|Bacteria,2J2IF@203682|Planctomycetes	203682|Planctomycetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRR25158343_k127_1683103_133	179408.Osc7112_1414	1.338e-13	74.0	COG0731@1|root,COG0731@2|Bacteria,1G1H0@1117|Cyanobacteria,1H7DQ@1150|Oscillatoriales	1117|Cyanobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158343_k127_1683103_155	65393.PCC7424_3775	0.0005346	44.0	COG0731@1|root,COG0731@2|Bacteria,1G1H0@1117|Cyanobacteria,3KFRC@43988|Cyanothece	1117|Cyanobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158343_k127_1683103_5	946077.W5A_05093	4.865e-225	705.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158343_k127_1683103_101	273116.14325467	1.366e-37	155.0	COG0446@1|root,arCOG01065@2157|Archaea,2Y306@28890|Euryarchaeota,24245@183967|Thermoplasmata	183967|Thermoplasmata	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_1683103_69	313596.RB2501_06965	3.137e-76	271.0	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
SRR25158343_k127_1683103_9	448385.sce0051	2.538e-208	665.0	COG0517@1|root,COG0517@2|Bacteria,1QZT1@1224|Proteobacteria,43CN4@68525|delta/epsilon subdivisions,2X7VC@28221|Deltaproteobacteria,2Z3IG@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158343_k127_1683103_112	714313.LSA_11450	3.669e-30	134.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae	91061|Bacilli	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158343_k127_1683103_123	1086011.HJ01_03285	1.616e-20	97.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_1683103_84	204669.Acid345_1498	1.776e-59	215.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_1683103_63	204669.Acid345_3828	2.763e-81	284.0	COG3303@1|root,COG3303@2|Bacteria,3Y999@57723|Acidobacteria,2JP5G@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SRR25158343_k127_1683103_87	1340493.JNIF01000003_gene1663	2.701e-53	211.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_26	1123248.KB893318_gene4193	2.501e-146	470.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1IT0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
SRR25158343_k127_1683103_49	1120965.AUBV01000006_gene2152	7.665e-110	365.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158343_k127_1683103_110	1380763.BG53_02405	1.155e-31	134.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,26SQY@186822|Paenibacillaceae	91061|Bacilli	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158343_k127_1683103_107	1449049.JONW01000008_gene530	1.684e-34	143.0	2C804@1|root,32VPI@2|Bacteria,1P2IC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_10	234267.Acid_0481	1.978e-186	595.0	COG1003@1|root,COG1003@2|Bacteria,3Y2UZ@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158343_k127_1683103_22	671143.DAMO_0706	6.508e-150	487.0	COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158343_k127_1683103_97	886377.Murru_1869	6.167e-45	166.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158343_k127_1683103_40	1150474.JQJI01000004_gene393	3.788e-125	411.0	COG0404@1|root,COG0404@2|Bacteria,2GC8B@200918|Thermotogae	200918|Thermotogae	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2007,GCV_T,GCV_T_C
SRR25158343_k127_1683103_134	929562.Emtol_4191	6.475e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_1683103_64	234267.Acid_3974	1.37e-79	274.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria	57723|Acidobacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
SRR25158343_k127_1683103_12	682795.AciX8_0803	2.939e-182	578.0	COG0334@1|root,COG0334@2|Bacteria,3Y3B4@57723|Acidobacteria,2JI4Q@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158343_k127_1683103_145	1267534.KB906758_gene2456	4.795e-07	63.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_56	926566.Terro_1501	4.676e-96	341.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Pep_M12B_propep,Reprolysin_5,Sortilin-Vps10
SRR25158343_k127_1683103_60	1379698.RBG1_1C00001G1766	1.734e-87	310.0	COG4365@1|root,COG4365@2|Bacteria,2NP8Q@2323|unclassified Bacteria	2|Bacteria	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
SRR25158343_k127_1683103_19	401053.AciPR4_0620	8.653e-159	524.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria,2JI29@204432|Acidobacteriia	204432|Acidobacteriia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158343_k127_1683103_4	1340493.JNIF01000003_gene4241	1.117e-259	831.0	COG4772@1|root,COG4772@2|Bacteria,3Y9AD@57723|Acidobacteria	57723|Acidobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1683103_15	1379270.AUXF01000002_gene1730	9.317e-176	567.0	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158343_k127_1683103_16	234267.Acid_1929	4.069e-168	560.0	COG2120@1|root,COG2120@2|Bacteria,3Y3BV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,PIG-L
SRR25158343_k127_1683103_38	401053.AciPR4_0365	1.661e-126	422.0	COG0165@1|root,COG0165@2|Bacteria,3Y7F3@57723|Acidobacteria,2JM7C@204432|Acidobacteriia	204432|Acidobacteriia	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158343_k127_1683103_115	1319815.HMPREF0202_02533	1.648e-27	119.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META
SRR25158343_k127_1683103_113	1120973.AQXL01000100_gene1127	1.985e-29	127.0	COG0546@1|root,COG0546@2|Bacteria,1V5HQ@1239|Firmicutes,4HM0E@91061|Bacilli,278JN@186823|Alicyclobacillaceae	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158343_k127_1683103_111	84531.JMTZ01000066_gene1920	1.915e-30	126.0	2E7CC@1|root,331VJ@2|Bacteria,1N8TM@1224|Proteobacteria,1SGJQ@1236|Gammaproteobacteria,1XB86@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF4087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4087
SRR25158343_k127_1683103_118	204669.Acid345_0154	3.535e-26	113.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria,2JN6E@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158343_k127_1683103_21	251221.35211608	3.348e-156	501.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158343_k127_1683103_130	1038859.AXAU01000001_gene2613	7.223e-15	80.0	2AKTJ@1|root,31BKK@2|Bacteria,1NYB1@1224|Proteobacteria,2UTN8@28211|Alphaproteobacteria,3K4H7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_78	1047013.AQSP01000057_gene1926	5.727e-65	239.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158343_k127_1683103_122	240015.ACP_1699	4.438e-22	101.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria,2JJPS@204432|Acidobacteriia	204432|Acidobacteriia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158343_k127_1683103_50	234267.Acid_7711	3.332e-109	362.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria	57723|Acidobacteria	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158343_k127_1683103_139	1095769.CAHF01000006_gene1893	2.744e-09	61.0	296I1@1|root,2ZTTI@2|Bacteria,1PAJI@1224|Proteobacteria,2W5RS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_80	1267535.KB906767_gene5080	6.877e-64	234.0	COG1503@1|root,COG1503@2|Bacteria,3Y6P2@57723|Acidobacteria	57723|Acidobacteria	J	eRF1 domain 3	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach,eRF1_3
SRR25158343_k127_1683103_29	686340.Metal_3938	1.033e-139	451.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,1XG2S@135618|Methylococcales	135618|Methylococcales	IQ	PFAM short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_1683103_141	56780.SYN_01757	1.823e-08	63.0	COG4966@1|root,COG4966@2|Bacteria,1Q8WE@1224|Proteobacteria,439J3@68525|delta/epsilon subdivisions,2X4VK@28221|Deltaproteobacteria,2MSHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158343_k127_1683103_116	1121423.JONT01000023_gene278	2.272e-27	127.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,2620J@186807|Peptococcaceae	186801|Clostridia	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158343_k127_1683103_2	929556.Solca_0720	3.18e-299	936.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_1683103_131	929562.Emtol_1676	8.687e-15	81.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_74	1295642.H839_06979	1.189e-68	243.0	COG1082@1|root,COG1082@2|Bacteria,1TS20@1239|Firmicutes,4HD4V@91061|Bacilli,1WG70@129337|Geobacillus	91061|Bacilli	G	Xylose isomerase-like TIM barrel	iolI	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158343_k127_1683103_62	1295642.H839_06949	3.826e-82	284.0	COG0673@1|root,COG0673@2|Bacteria,1TW1D@1239|Firmicutes,4I4QS@91061|Bacilli,1WFPB@129337|Geobacillus	91061|Bacilli	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158343_k127_1683103_117	639030.JHVA01000001_gene673	2.314e-26	120.0	2A9J8@1|root,30YRM@2|Bacteria,3Y4IZ@57723|Acidobacteria,2JJDB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_65	429009.Adeg_1474	1.355e-78	271.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158343_k127_1683103_129	204669.Acid345_0720	6.298e-16	81.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRR25158343_k127_1683103_37	246194.CHY_1570	2.865e-128	435.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,42F4K@68295|Thermoanaerobacterales	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR25158343_k127_1683103_14	526227.Mesil_3337	1.571e-176	566.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
SRR25158343_k127_1683103_46	742735.HMPREF9467_03271	9.41e-116	385.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,21YGP@1506553|Lachnoclostridium	186801|Clostridia	J	phenylalanyl-tRNA synthetase (alpha subunit)	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158343_k127_1683103_98	240015.ACP_2248	7.007e-42	158.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158343_k127_1683103_125	903818.KI912268_gene2462	3.317e-18	86.0	COG0291@1|root,COG0291@2|Bacteria,3Y5US@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158343_k127_1683103_85	1424334.W822_15190	1.602e-56	203.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,3T1Y6@506|Alcaligenaceae	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158343_k127_1683103_7	234267.Acid_7295	3.121e-214	683.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158343_k127_1683103_82	1267535.KB906767_gene4499	4.623e-60	213.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_1683103_152	1173027.Mic7113_0582	8.729e-05	50.0	COG3409@1|root,COG3409@2|Bacteria,1GR82@1117|Cyanobacteria,1HIA0@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_77	32057.KB217472_gene7872	1.535e-65	251.0	COG1075@1|root,COG1361@1|root,COG1572@1|root,COG2931@1|root,COG1075@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
SRR25158343_k127_1683103_71	1434929.X946_1416	1.973e-71	276.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2VZN8@28216|Betaproteobacteria,1KGFG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17
SRR25158343_k127_1683103_27	234267.Acid_7916	6.055e-145	507.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_1683103_57	886293.Sinac_4633	5.093e-96	332.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_1683103_73	468059.AUHA01000002_gene563	3.189e-69	259.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
SRR25158343_k127_1683103_72	1267533.KB906733_gene3362	5.953e-71	275.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158343_k127_1683103_28	234267.Acid_7916	1.711e-140	495.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_1683103_47	1232410.KI421413_gene941	8.191e-115	381.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43RY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158343_k127_1683103_142	1112216.JH594425_gene2015	3.652e-08	55.0	2EFZF@1|root,339RM@2|Bacteria,1Q79X@1224|Proteobacteria,2UWHC@28211|Alphaproteobacteria,2K7QX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_67	324602.Caur_3812	1.823e-77	270.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	-	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158343_k127_1683103_119	204669.Acid345_2058	6.091e-24	113.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_1683103_83	558152.IQ37_11810	1.103e-59	211.0	2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,1I8KU@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1683103_150	1206737.BAGF01000045_gene2865	6.901e-05	54.0	COG3409@1|root,COG3409@2|Bacteria,2HJ8T@201174|Actinobacteria,4G5V7@85025|Nocardiaceae	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_3	926550.CLDAP_29100	1.202e-272	847.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158343_k127_1683103_120	929556.Solca_0948	2.137e-23	111.0	2EAV9@1|root,334WR@2|Bacteria,4P8W8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_61	746697.Aeqsu_2426	1.276e-82	286.0	28P53@1|root,2ZC07@2|Bacteria,4NWI6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_41	706587.Desti_1404	3.883e-125	429.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
SRR25158343_k127_1683103_48	63737.Npun_R0239	2.876e-110	366.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158343_k127_1683103_109	1382359.JIAL01000001_gene2631	4.886e-34	146.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_1683103_34	926550.CLDAP_27470	4.941e-132	434.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158343_k127_1683103_6	1521187.JPIM01000116_gene3552	7.246e-222	699.0	COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi,3772R@32061|Chloroflexia	32061|Chloroflexia	E	PFAM phenylalanine histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158343_k127_1683103_104	1267534.KB906755_gene4754	3.763e-36	141.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria,2JJIE@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158343_k127_1683103_93	204669.Acid345_1996	7.762e-47	174.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria,2JJ48@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158343_k127_1683103_36	234267.Acid_1288	2.674e-128	427.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158343_k127_1683103_95	633149.Bresu_1179	1.551e-45	177.0	COG2856@1|root,COG2856@2|Bacteria,1N5MY@1224|Proteobacteria,2TYKC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Putative metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4344
SRR25158343_k127_1683103_146	497964.CfE428DRAFT_2100	1.09e-06	58.0	2EQI1@1|root,33I41@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878
SRR25158343_k127_1683103_17	997296.PB1_01175	8.888e-165	526.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
SRR25158343_k127_1683103_39	204669.Acid345_4390	1.654e-125	436.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158343_k127_1683103_30	1278073.MYSTI_04848	1.598e-139	457.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SRR25158343_k127_1683103_102	316274.Haur_0717	4.877e-37	160.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_1683103_55	234267.Acid_5981	5.228e-98	334.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1683103_70	1340493.JNIF01000003_gene4032	1.637e-73	263.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1683103_31	1267534.KB906754_gene3139	2.096e-139	447.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria,2JHSN@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158343_k127_1683103_105	497964.CfE428DRAFT_4951	1.071e-35	142.0	COG5485@1|root,COG5485@2|Bacteria,46T9K@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158343_k127_1683103_106	1123234.AUKI01000020_gene719	2.11e-35	140.0	COG0824@1|root,COG0824@2|Bacteria,4NSIG@976|Bacteroidetes,1I42Y@117743|Flavobacteriia	976|Bacteroidetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
SRR25158343_k127_1683103_86	1232410.KI421424_gene1665	5.051e-56	198.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,43SGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NDK	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158343_k127_1683103_151	397278.JOJN01000010_gene2267	7.964e-05	54.0	29X9F@1|root,30IYX@2|Bacteria,2HKUX@201174|Actinobacteria,4DVIN@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158343_k127_1683103_92	1340493.JNIF01000003_gene1773	1.102e-51	189.0	COG1143@1|root,COG1143@2|Bacteria,3Y371@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SRR25158343_k127_1683103_114	240015.ACP_3265	9.369e-29	123.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	irrE	-	-	ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF4344,Peptidase_M78
SRR25158343_k127_1683103_54	1379698.RBG1_1C00001G1345	9.315e-99	337.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
SRR25158343_k127_1683103_132	1340493.JNIF01000004_gene73	4.031e-14	84.0	COG3712@1|root,COG3712@2|Bacteria,3Y5MB@57723|Acidobacteria	57723|Acidobacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158343_k127_1683103_140	110663.KI911558_gene174	5.571e-09	67.0	COG1266@1|root,COG1266@2|Bacteria,1G0ZJ@1117|Cyanobacteria,1GZ8P@1129|Synechococcus	1117|Cyanobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158343_k127_1683103_79	926561.KB900617_gene2131	8.307e-65	230.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158343_k127_1683103_8	555079.Toce_2181	1.062e-212	674.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
SRR25158343_k127_1683103_52	329726.AM1_2195	1.035e-102	340.0	COG2877@1|root,COG2877@2|Bacteria,1G2XI@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158343_k127_1683103_156	512565.AMIS_12650	0.0005568	53.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4D90U@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_1683103_96	484770.UFO1_4213	3.611e-45	169.0	COG1778@1|root,COG1778@2|Bacteria,1V5JJ@1239|Firmicutes,4H4ID@909932|Negativicutes	909932|Negativicutes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
SRR25158343_k127_1683103_108	1487953.JMKF01000074_gene3684	3.975e-34	135.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158343_k127_1683103_23	886293.Sinac_0207	1.369e-148	479.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
SRR25158343_k127_1683103_100	1123073.KB899242_gene1384	1.462e-38	151.0	COG0454@1|root,COG0456@2|Bacteria,1RDH4@1224|Proteobacteria,1SCMT@1236|Gammaproteobacteria,1X66P@135614|Xanthomonadales	135614|Xanthomonadales	K	acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158343_k127_1683103_144	2754.EH55_11420	4.377e-07	61.0	2DRHE@1|root,33BRN@2|Bacteria,3TBTV@508458|Synergistetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1683103_103	1267534.KB906759_gene1860	1.791e-36	156.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_91	489825.LYNGBM3L_21210	4.274e-33	129.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_1705922_16	1123248.KB893322_gene633	5.295e-151	486.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158343_k127_1705922_90	1173026.Glo7428_0927	1.319e-33	137.0	COG0110@1|root,COG0110@2|Bacteria,1G9TY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158343_k127_1705922_27	1123248.KB893322_gene634	8.772e-111	361.0	COG0110@1|root,COG0110@2|Bacteria,4NVA6@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158343_k127_1705922_81	192952.MM_1142	6.394e-38	158.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,2N9R4@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1705922_83	396588.Tgr7_2371	2.761e-37	159.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria	1224|Proteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158343_k127_1705922_94	1274524.BSONL12_00982	1.097e-31	141.0	COG2120@1|root,COG2120@2|Bacteria,1V2QU@1239|Firmicutes,4HGPT@91061|Bacilli,1ZGPD@1386|Bacillus	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158343_k127_1705922_138	868595.Desca_2582	0.000452	51.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,2603G@186807|Peptococcaceae	186801|Clostridia	S	PFAM Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
SRR25158343_k127_1705922_14	1340493.JNIF01000003_gene3519	2.235e-170	576.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1705922_33	1267534.KB906754_gene2801	7.424e-93	326.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158343_k127_1705922_32	243231.GSU0099	3.998e-96	317.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SRR25158343_k127_1705922_82	1232410.KI421424_gene1859	1.867e-37	148.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SRR25158343_k127_1705922_37	1382359.JIAL01000001_gene1385	8.164e-90	307.0	COG0391@1|root,COG0391@2|Bacteria,3Y3ZE@57723|Acidobacteria,2JITK@204432|Acidobacteriia	204432|Acidobacteriia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158343_k127_1705922_20	717605.Theco_3721	6.785e-126	418.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,26RIB@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SRR25158343_k127_1705922_4	671143.DAMO_1991	3.123e-233	736.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
SRR25158343_k127_1705922_104	1347087.CBYO010000022_gene3857	3.37e-22	101.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,4HKWP@91061|Bacilli	91061|Bacilli	P	rhodanese	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158343_k127_1705922_59	1210884.HG799465_gene11742	8.17e-62	230.0	2AFAW@1|root,315A9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_45	1210884.HG799465_gene11742	4.842e-77	271.0	2AFAW@1|root,315A9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_77	649349.Lbys_0290	1.434e-39	159.0	2AFAW@1|root,315A9@2|Bacteria,4P2W4@976|Bacteroidetes,47UP5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_78	1123276.KB893251_gene3599	2.058e-39	156.0	2EBPD@1|root,335PG@2|Bacteria,4NW88@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_61	1047013.AQSP01000089_gene1181	4.186e-61	242.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158343_k127_1705922_21	234267.Acid_7916	1.695e-122	437.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_1705922_18	1301100.HG529233_gene7407	1.068e-132	434.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,36E24@31979|Clostridiaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158343_k127_1705922_15	649638.Trad_1384	2.948e-166	538.0	COG2041@1|root,COG2041@2|Bacteria,1WI25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158343_k127_1705922_8	661478.OP10G_1529	2.778e-204	651.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158343_k127_1705922_112	1047013.AQSP01000034_gene1652	2.248e-19	98.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158343_k127_1705922_64	367737.Abu_0830	1.293e-56	214.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2YTK1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SRR25158343_k127_1705922_11	1267535.KB906767_gene998	3.326e-186	612.0	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07680	ko02020,ko02024,map02020,map02024	M00476	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HAMP,HATPase_c_2,SpoIIE
SRR25158343_k127_1705922_65	1192034.CAP_5359	1.811e-56	203.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2YV3U@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158343_k127_1705922_89	880073.Calab_3344	2.947e-35	145.0	COG0698@1|root,COG0698@2|Bacteria,2NPF4@2323|unclassified Bacteria	2|Bacteria	G	ribose 5-phosphate isomerase B	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
SRR25158343_k127_1705922_133	1313421.JHBV01000030_gene2185	5.854e-06	55.0	2CB0Q@1|root,33N1Z@2|Bacteria,4NY6D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_43	1384057.CD33_15630	1.037e-80	278.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3IX5U@400634|Lysinibacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158343_k127_1705922_57	357808.RoseRS_1529	1.537e-62	242.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_1705922_126	533247.CRD_02400	4.009e-12	78.0	COG0457@1|root,COG0457@2|Bacteria,1G649@1117|Cyanobacteria,1HM2D@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_1705922_86	383372.Rcas_0336	3.512e-36	157.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_1705922_100	113355.CM001775_gene2675	7.316e-25	113.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	113355.CM001775_gene2675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_130	666681.M301_2336	3.469e-09	69.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
SRR25158343_k127_1705922_116	1382306.JNIM01000001_gene2191	3.021e-17	92.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	1382306.JNIM01000001_gene2191|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_56	383372.Rcas_0336	7.742e-63	239.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_1705922_23	748280.NH8B_3719	2.658e-118	388.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,2KPV7@206351|Neisseriales	206351|Neisseriales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158343_k127_1705922_67	521674.Plim_3770	7.135e-55	198.0	COG1018@1|root,COG2717@1|root,COG1018@2|Bacteria,COG2717@2|Bacteria,2J05J@203682|Planctomycetes	203682|Planctomycetes	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,Ferric_reduct,NAD_binding_1
SRR25158343_k127_1705922_60	240015.ACP_1819	2.036e-61	221.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158343_k127_1705922_36	251221.35213116	5.65e-92	314.0	COG0793@1|root,COG0793@2|Bacteria,1G58N@1117|Cyanobacteria	1117|Cyanobacteria	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
SRR25158343_k127_1705922_124	649743.HMPREF0972_00732	4.932e-14	79.0	COG1309@1|root,COG1309@2|Bacteria,2HJXI@201174|Actinobacteria,4D4C9@85005|Actinomycetales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158343_k127_1705922_28	1121373.KB903643_gene3643	4.046e-106	355.0	COG2220@1|root,COG2220@2|Bacteria,4NI69@976|Bacteroidetes,47K8S@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158343_k127_1705922_128	237368.SCABRO_02455	2.376e-10	66.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158343_k127_1705922_42	204669.Acid345_1347	4.732e-81	278.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158343_k127_1705922_95	756272.Plabr_0144	1.214e-31	136.0	COG5012@1|root,COG5012@2|Bacteria,2IZ1E@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,HTH_17
SRR25158343_k127_1705922_72	742733.HMPREF9469_02308	1.005e-46	173.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,21ZYM@1506553|Lachnoclostridium	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158343_k127_1705922_13	240015.ACP_2846	5.724e-174	555.0	COG0112@1|root,COG0112@2|Bacteria,3Y2JB@57723|Acidobacteria,2JI87@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158343_k127_1705922_111	1265503.KB905176_gene4082	1.824e-19	93.0	COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria,2Q86C@267889|Colwelliaceae	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_49	1237149.C900_01842	9.572e-68	238.0	2C2FI@1|root,32T83@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_0	575540.Isop_3282	0.0	1196.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158343_k127_1705922_73	935567.JAES01000019_gene1024	2.691e-46	175.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158343_k127_1705922_129	861299.J421_1420	4.882e-10	72.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	SLH,YkuD
SRR25158343_k127_1705922_119	56107.Cylst_1276	2.257e-16	90.0	COG1876@1|root,COG1876@2|Bacteria,1G4P0@1117|Cyanobacteria,1HIMP@1161|Nostocales	1117|Cyanobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	-	-	-	-	-	-	-	-	-	-	VanY
SRR25158343_k127_1705922_118	504472.Slin_2490	1.281e-16	85.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,47PDQ@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_1705922_123	595460.RRSWK_06362	3.265e-14	76.0	COG1595@1|root,COG1595@2|Bacteria,2IZXS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158343_k127_1705922_5	234267.Acid_5526	2.674e-231	725.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158343_k127_1705922_40	314345.SPV1_01002	3.606e-85	289.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_1705922_54	1123393.KB891333_gene2538	1.647e-63	225.0	COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,2VQIC@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRR25158343_k127_1705922_125	502025.Hoch_6233	1.137e-12	82.0	2EY5V@1|root,33REI@2|Bacteria,1NQKK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_76	1265505.ATUG01000001_gene4606	3.371e-40	156.0	COG3409@1|root,COG3409@2|Bacteria,1RBD0@1224|Proteobacteria	1224|Proteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
SRR25158343_k127_1705922_102	1121396.KB892979_gene1667	5.365e-24	114.0	2F8WN@1|root,3418I@2|Bacteria,1NYJX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_75	1254432.SCE1572_01405	3.466e-41	166.0	COG3409@1|root,COG3409@2|Bacteria,1QEQD@1224|Proteobacteria,4319J@68525|delta/epsilon subdivisions,2WWM3@28221|Deltaproteobacteria,2Z1Q7@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_122	1265505.ATUG01000001_gene4607	2.747e-14	78.0	2DY7W@1|root,348JE@2|Bacteria,1P2KV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_121	1183438.GKIL_3544	2.141e-14	79.0	COG1716@1|root,COG1716@2|Bacteria,1G9NG@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
SRR25158343_k127_1705922_80	1121396.KB892979_gene1668	1.199e-38	151.0	COG1716@1|root,COG1716@2|Bacteria,1N47K@1224|Proteobacteria,431RX@68525|delta/epsilon subdivisions,2WWF6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
SRR25158343_k127_1705922_10	443144.GM21_1216	2.663e-186	610.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
SRR25158343_k127_1705922_26	1131269.AQVV01000016_gene1877	3.34e-112	393.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	MA20_43810	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1705922_46	1382359.JIAL01000001_gene200	6.493e-77	264.0	COG4181@1|root,COG4181@2|Bacteria,3Y3RU@57723|Acidobacteria,2JI42@204432|Acidobacteriia	204432|Acidobacteriia	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_1705922_70	330214.NIDE0349	3.478e-52	194.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
SRR25158343_k127_1705922_17	1340493.JNIF01000003_gene1702	6.71e-148	477.0	COG0498@1|root,COG0498@2|Bacteria,3Y2GX@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158343_k127_1705922_84	926549.KI421517_gene3914	6.983e-37	142.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.14.99.48,1.14.99.57	ko:K07145,ko:K21481	ko00860,ko01110,map00860,map01110	-	R10468,R10510	RC03185	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158343_k127_1705922_25	926549.KI421517_gene3913	1.592e-115	383.0	COG5012@1|root,COG5012@2|Bacteria,4NRCW@976|Bacteroidetes,47UR1@768503|Cytophagia	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158343_k127_1705922_48	1121413.JMKT01000009_gene2017	1.585e-72	253.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZNH@68525|delta/epsilon subdivisions,2WV22@28221|Deltaproteobacteria,2MG18@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158343_k127_1705922_99	1121413.JMKT01000011_gene2368	3.82e-26	125.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1RGCV@1224|Proteobacteria,42YPK@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,Response_reg
SRR25158343_k127_1705922_30	1144275.COCOR_00615	1.526e-99	350.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2YXU5@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158343_k127_1705922_110	483219.LILAB_23455	1.182e-19	93.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1QUJ7@1224|Proteobacteria,43BJF@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Response_reg,sCache_like
SRR25158343_k127_1705922_6	1192034.CAP_7615	1.398e-211	677.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,42M4B@68525|delta/epsilon subdivisions,2WJDI@28221|Deltaproteobacteria,2YZG3@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158343_k127_1705922_103	639030.JHVA01000001_gene3555	7.29e-24	117.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
SRR25158343_k127_1705922_74	1267533.KB906733_gene2910	8.168e-44	174.0	COG0577@1|root,COG0577@2|Bacteria,3Y32V@57723|Acidobacteria,2JI59@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_1705922_134	929562.Emtol_2956	7.104e-05	55.0	COG5305@1|root,COG5305@2|Bacteria,4NHT8@976|Bacteroidetes,47MIS@768503|Cytophagia	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_1705922_105	1267533.KB906738_gene2439	2.869e-21	106.0	COG0392@1|root,COG0558@1|root,COG0392@2|Bacteria,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	CDP-OH_P_transf,LPG_synthase_TM
SRR25158343_k127_1705922_7	1174528.JH992893_gene5975	3.29e-206	655.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1G15G@1117|Cyanobacteria,1JHXK@1189|Stigonemataceae	1117|Cyanobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158343_k127_1705922_97	376686.Fjoh_0934	5.513e-29	118.0	2CMS6@1|root,32SFE@2|Bacteria,4NWI0@976|Bacteroidetes,1IAQW@117743|Flavobacteriia,2NWVT@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1705922_117	1122221.JHVI01000004_gene147	7.24e-17	81.0	2CMS6@1|root,32SFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1705922_68	861299.J421_3644	5.378e-54	198.0	COG0586@1|root,COG0586@2|Bacteria,1ZTJB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158343_k127_1705922_35	1173020.Cha6605_5370	5.478e-92	312.0	COG1881@1|root,COG1881@2|Bacteria,1G1EC@1117|Cyanobacteria	1117|Cyanobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
SRR25158343_k127_1705922_55	1479237.JMLY01000001_gene2174	7.646e-63	222.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158343_k127_1705922_136	1301098.PKB_4792	0.0001533	51.0	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	pilV	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SRR25158343_k127_1705922_63	204669.Acid345_2003	4.396e-59	233.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,DUF3494,PilX_N
SRR25158343_k127_1705922_115	873449.STRCR_0408	1.785e-17	85.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli	91061|Bacilli	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	yabO	-	-	-	-	-	-	-	-	-	-	-	S4
SRR25158343_k127_1705922_113	1267533.KB906733_gene3500	3.035e-19	100.0	COG0760@1|root,COG0760@2|Bacteria,3Y3V9@57723|Acidobacteria,2JICA@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
SRR25158343_k127_1705922_2	240015.ACP_2078	2.624e-297	951.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158343_k127_1705922_19	1304888.ATWF01000001_gene1132	1.259e-132	445.0	COG1190@1|root,COG1190@2|Bacteria,2GEUY@200930|Deferribacteres	200930|Deferribacteres	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158343_k127_1705922_108	863365.XHC_2071	5.61e-20	94.0	COG0457@1|root,COG0457@2|Bacteria,1NN7J@1224|Proteobacteria,1SSNA@1236|Gammaproteobacteria,1XB3N@135614|Xanthomonadales	135614|Xanthomonadales	S	Regulator of ribonuclease activity B	-	-	-	-	-	-	-	-	-	-	-	-	RraB
SRR25158343_k127_1705922_87	530564.Psta_1991	4.397e-36	141.0	2E5ES@1|root,3306N@2|Bacteria,2J0XS@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_38	1385935.N836_32435	5.498e-88	298.0	COG0697@1|root,COG0697@2|Bacteria,1G4U5@1117|Cyanobacteria,1HFB2@1150|Oscillatoriales	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158343_k127_1705922_93	1123242.JH636434_gene4709	1.499e-32	129.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158343_k127_1705922_106	244582.JQAK01000001_gene1753	3.953e-21	94.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,47FN6@766|Rickettsiales	766|Rickettsiales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158343_k127_1705922_109	1296415.JACC01000043_gene72	9.002e-20	95.0	2DT2Q@1|root,33IF9@2|Bacteria,4NYNC@976|Bacteroidetes,1I6R7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_127	631362.Thi970DRAFT_04594	4.093e-12	72.0	2EI34@1|root,33BUM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_71	204669.Acid345_0559	1.491e-47	184.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,LolA_like,MacB_PCD
SRR25158343_k127_1705922_98	373903.Hore_11160	2.013e-27	126.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,3WBJY@53433|Halanaerobiales	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1705922_101	1340493.JNIF01000003_gene1732	9e-25	114.0	28VQR@1|root,2ZHSP@2|Bacteria,3Y91E@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_24	1340493.JNIF01000004_gene993	2.647e-117	389.0	COG0438@1|root,COG0438@2|Bacteria,3Y67M@57723|Acidobacteria	57723|Acidobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_1705922_47	234267.Acid_2766	2.765e-75	268.0	COG0613@1|root,COG0613@2|Bacteria,3Y451@57723|Acidobacteria	57723|Acidobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_50	1340493.JNIF01000004_gene275	6.288e-67	254.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene275|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_131	1379281.AVAG01000011_gene1293	4.256e-08	67.0	COG2304@1|root,COG2304@2|Bacteria,1R845@1224|Proteobacteria,43D88@68525|delta/epsilon subdivisions,2X8EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_1705922_34	575590.HMPREF0156_01070	9.626e-93	340.0	arCOG06431@1|root,2ZA78@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_29	675812.VHA_003485	6.228e-103	351.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XSYD@135623|Vibrionales	135623|Vibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158343_k127_1705922_135	926566.Terro_3361	7.92e-05	51.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,DUF2637,TonB_C,YXWGXW
SRR25158343_k127_1705922_120	1056820.KB900631_gene2330	1.691e-15	80.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,2PNXY@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	Exonuclease VII small subunit	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158343_k127_1705922_114	391735.Veis_1494	4.235e-18	89.0	2DX4M@1|root,343C2@2|Bacteria,1P37C@1224|Proteobacteria,2W4MW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1705922_58	794903.OPIT5_07380	4.141e-62	221.0	COG0670@1|root,COG0670@2|Bacteria,46VEY@74201|Verrucomicrobia,3K9GN@414999|Opitutae	414999|Opitutae	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
SRR25158343_k127_1705922_85	272134.KB731324_gene2628	1.341e-36	143.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158343_k127_1705922_39	171693.BN988_03539	1.193e-85	294.0	COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli,23K1N@182709|Oceanobacillus	91061|Bacilli	S	Sulfatase-modifying factor enzyme 1	pkn1	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR25158343_k127_1705922_22	661478.OP10G_1297	2.442e-119	392.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158343_k127_1705922_69	342610.Patl_1507	4.186e-53	205.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,1T3J3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1705922_132	494419.ALPM01000075_gene1569	5.218e-07	58.0	COG0810@1|root,COG3401@1|root,COG4733@1|root,COG0810@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
SRR25158343_k127_1705922_96	1173024.KI912149_gene6476	5.01e-31	127.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158343_k127_1705922_31	1267533.KB906738_gene2031	5.804e-97	324.0	COG1398@1|root,COG1398@2|Bacteria,3Y3F9@57723|Acidobacteria,2JHWH@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158343_k127_1705922_1	926550.CLDAP_06210	0.0	1091.0	COG1274@1|root,COG1274@2|Bacteria,2G7VM@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158343_k127_1705922_66	945713.IALB_1247	5.816e-56	206.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158343_k127_1705922_88	1340493.JNIF01000004_gene771	1.899e-35	148.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	-	GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858	1.18.1.3	ko:K00529,ko:K04755,ko:K08952,ko:K08953,ko:K08954,ko:K15765	ko00071,ko00360,ko00623,ko00920,ko01100,ko01120,ko01220,map00071,map00360,map00623,map00920,map01100,map01120,map01220	M00538,M00545	R02000,R02550,R03562,R05666,R06782,R06783,R09513	RC00098,RC00269,RC00490,RC02556	br01602,ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	FAD_binding_6,Fer2
SRR25158343_k127_1705922_44	1089547.KB913013_gene1472	1.565e-79	273.0	COG1633@1|root,COG1633@2|Bacteria,4NIDS@976|Bacteroidetes,47K4D@768503|Cytophagia	976|Bacteroidetes	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158343_k127_1705922_52	314256.OG2516_17600	1.131e-65	234.0	COG1633@1|root,COG1633@2|Bacteria,1R8NN@1224|Proteobacteria,2VG99@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158343_k127_1705922_79	1303518.CCALI_02071	8.512e-39	149.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	sirR	-	-	ko:K03709,ko:K04758,ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.15	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158343_k127_1705922_9	452637.Oter_3586	2.635e-199	629.0	COG1914@1|root,COG1914@2|Bacteria,46SH7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
SRR25158343_k127_1705922_62	63737.Npun_F2502	2.055e-60	217.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,1HMVQ@1161|Nostocales	1117|Cyanobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
SRR25158343_k127_1705922_51	204669.Acid345_1221	8.395e-67	229.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158343_k127_1705922_53	1121440.AUMA01000007_gene1303	2.14e-64	223.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MAZM@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158343_k127_1705922_3	289377.HL41_05460	9.105e-281	878.0	COG0480@1|root,COG0480@2|Bacteria,2GH6R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_1705922_107	639030.JHVA01000001_gene1556	1.564e-20	90.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_1772108_3	1122970.AUHC01000001_gene523	8.697e-06	50.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1772108_1	469383.Cwoe_1095	3.309e-110	364.0	COG0524@1|root,COG0524@2|Bacteria,2HPJD@201174|Actinobacteria,4CQWU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158343_k127_1772108_2	1121904.ARBP01000003_gene6272	1.598e-45	168.0	COG0346@1|root,COG0346@2|Bacteria,4NQ3F@976|Bacteroidetes,47VM6@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158343_k127_1772108_0	755178.Cyan10605_1821	8.489e-209	657.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158343_k127_1774492_54	1122970.AUHC01000001_gene523	1.22e-05	50.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1774492_37	41431.PCC8801_1300	2.124e-42	169.0	COG0457@1|root,COG0457@2|Bacteria,1GIT8@1117|Cyanobacteria,3KHZU@43988|Cyanothece	1117|Cyanobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8,Trypsin_2
SRR25158343_k127_1774492_31	1121104.AQXH01000002_gene783	5.182e-53	196.0	2CWY1@1|root,32T0M@2|Bacteria,4P319@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1774492_17	1122604.JONR01000033_gene34	2.094e-84	286.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158343_k127_1774492_26	1254432.SCE1572_26545	6.274e-66	239.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158343_k127_1774492_33	515635.Dtur_0526	1.071e-47	175.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158343_k127_1774492_4	357808.RoseRS_1917	1.751e-171	544.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi,37708@32061|Chloroflexia	32061|Chloroflexia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
SRR25158343_k127_1774492_30	1519464.HY22_04810	2.203e-53	196.0	COG0177@1|root,COG0177@2|Bacteria,1FEVW@1090|Chlorobi	1090|Chlorobi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158343_k127_1774492_34	521098.Aaci_0535	2.1e-46	174.0	COG0346@1|root,COG0346@2|Bacteria,1V6K2@1239|Firmicutes,4HJ55@91061|Bacilli	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158343_k127_1774492_39	278963.ATWD01000001_gene2665	4.832e-40	153.0	COG0640@1|root,COG0640@2|Bacteria,3Y7J1@57723|Acidobacteria,2JMRU@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158343_k127_1774492_23	667014.Thein_0763	8.718e-73	252.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158343_k127_1774492_22	869210.Marky_1959	4.368e-73	258.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158343_k127_1774492_49	29581.BW37_01941	2.607e-16	87.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,2VVTK@28216|Betaproteobacteria,4753V@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158343_k127_1774492_36	1379698.RBG1_1C00001G1645	1.194e-42	167.0	COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
SRR25158343_k127_1774492_44	644282.Deba_1225	7.546e-29	127.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,1PGJ3@1224|Proteobacteria,4315J@68525|delta/epsilon subdivisions,2WWDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
SRR25158343_k127_1774492_6	309799.DICTH_0172	2.148e-146	481.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158343_k127_1774492_7	929703.KE386491_gene507	3.219e-142	456.0	COG1940@1|root,COG1940@2|Bacteria,4NGC1@976|Bacteroidetes,47KEB@768503|Cytophagia	976|Bacteroidetes	GK	PFAM ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158343_k127_1774492_24	234267.Acid_6262	9.002e-73	258.0	2DNAS@1|root,32WH6@2|Bacteria,3Y5UC@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1774492_25	1267535.KB906767_gene5053	1.02e-72	255.0	COG2367@1|root,COG2367@2|Bacteria,3Y3UF@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158343_k127_1774492_15	880073.Calab_2509	1.746e-97	322.0	COG0603@1|root,COG0603@2|Bacteria,2NPD6@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SRR25158343_k127_1774492_48	595460.RRSWK_02008	1.372e-16	89.0	2FECS@1|root,346CJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1774492_14	401053.AciPR4_1386	1.828e-98	336.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria,2JHY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_1774492_18	1121957.ATVL01000013_gene80	2.148e-80	286.0	COG1566@1|root,COG1566@2|Bacteria,4NEQJ@976|Bacteroidetes,47M5R@768503|Cytophagia	976|Bacteroidetes	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158343_k127_1774492_3	941449.dsx2_0707	4.947e-194	617.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,42KZU@68525|delta/epsilon subdivisions,2WJ6T@28221|Deltaproteobacteria,2M7RJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRR25158343_k127_1774492_20	1237149.C900_04110	1.111e-76	261.0	COG4430@1|root,COG4430@2|Bacteria,4NG4C@976|Bacteroidetes,47P8T@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
SRR25158343_k127_1774492_35	382464.ABSI01000005_gene1264	9.308e-43	163.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158343_k127_1774492_8	1123248.KB893324_gene1707	3.319e-125	404.0	COG0457@1|root,COG0457@2|Bacteria,4PN62@976|Bacteroidetes,1IQEB@117747|Sphingobacteriia	976|Bacteroidetes	S	Rifampin ADP-ribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Arr-ms
SRR25158343_k127_1774492_27	1121091.AUMP01000006_gene4227	2.183e-56	197.0	COG0346@1|root,COG0346@2|Bacteria,1V3YM@1239|Firmicutes,4HH9D@91061|Bacilli	91061|Bacilli	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158343_k127_1774492_52	485917.Phep_2383	3.502e-14	72.0	COG0346@1|root,COG0346@2|Bacteria,4NMH9@976|Bacteroidetes,1ISMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158343_k127_1774492_47	172045.KS04_19795	3.437e-19	88.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia,34RHF@308865|Elizabethkingia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
SRR25158343_k127_1774492_11	1144313.PMI10_00125	4.079e-101	338.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5M@976|Bacteroidetes,1I10P@117743|Flavobacteriia,2NUSY@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
SRR25158343_k127_1774492_51	1454007.JAUG01000059_gene3550	6.982e-15	76.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1INSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRR25158343_k127_1774492_32	575540.Isop_1666	2.92e-49	192.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
SRR25158343_k127_1774492_0	314607.KB13_1285	1.113e-310	966.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,1KQ66@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRR25158343_k127_1774492_28	1122182.KB903837_gene3800	2.776e-56	211.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4DM5Z@85008|Micromonosporales	201174|Actinobacteria	I	Carboxylesterase family	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
SRR25158343_k127_1774492_1	517418.Ctha_1856	1.344e-213	681.0	COG0488@1|root,COG0488@2|Bacteria,1FDIP@1090|Chlorobi	1090|Chlorobi	S	PFAM ABC transporter related	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158343_k127_1774492_5	929556.Solca_2505	1.194e-168	540.0	COG3934@1|root,COG3934@2|Bacteria,4NH10@976|Bacteroidetes,1IRN6@117747|Sphingobacteriia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42
SRR25158343_k127_1774492_43	1173022.Cri9333_3037	4.438e-37	142.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HAQ3@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158343_k127_1774492_21	314230.DSM3645_07485	4.204e-74	261.0	COG0673@1|root,COG0673@2|Bacteria,2J216@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158343_k127_1774492_10	661478.OP10G_2332	8.733e-120	396.0	COG2898@1|root,COG2898@2|Bacteria	2|Bacteria	K	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156
SRR25158343_k127_1774492_46	32057.KB217483_gene9468	8.368e-22	106.0	COG1404@1|root,COG1928@1|root,COG1404@2|Bacteria,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109,3.2.1.99	ko:K00728,ko:K06113,ko:K12685	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43,GT39	-	PMT,PMT_4TMC,SLH
SRR25158343_k127_1774492_40	1121481.AUAS01000001_gene4877	6.63e-40	156.0	COG3652@1|root,COG3652@2|Bacteria,4NQE9@976|Bacteroidetes,47QZE@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRR25158343_k127_1774492_41	861299.J421_3014	2.369e-38	145.0	2DJKR@1|root,32X86@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1774492_16	234267.Acid_7242	1.198e-85	294.0	COG3391@1|root,COG3391@2|Bacteria,3Y2SU@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158343_k127_1774492_19	1122221.JHVI01000028_gene1302	3.051e-80	270.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158343_k127_1774492_13	469383.Cwoe_4200	2.312e-99	334.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4CQBI@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158343_k127_1774492_42	1499967.BAYZ01000149_gene6772	2.993e-38	162.0	2EMQ9@1|root,33FCS@2|Bacteria	2|Bacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158343_k127_1774492_12	518766.Rmar_0304	1e-100	338.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1FJQT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	4Fe-4S double cluster binding domain	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRR25158343_k127_1774492_2	1267534.KB906758_gene2303	5.691e-200	669.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Y@57723|Acidobacteria,2JKVG@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1774492_38	886293.Sinac_7078	2.673e-42	170.0	COG0644@1|root,COG0644@2|Bacteria,2IZDK@203682|Planctomycetes	203682|Planctomycetes	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158343_k127_1774492_29	1121422.AUMW01000003_gene994	1.807e-53	200.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,24BDQ@186801|Clostridia,261Z4@186807|Peptococcaceae	186801|Clostridia	S	Zn-dependent hydrolase, glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158343_k127_1774492_9	1128398.Curi_c19700	6.358e-120	402.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2680K@186813|unclassified Clostridiales	186801|Clostridia	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158343_k127_1774492_50	204669.Acid345_0269	1.074e-15	80.0	2ENGH@1|root,33G40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1774492_55	1295642.H839_07279	7.605e-05	53.0	2E9CG@1|root,333K5@2|Bacteria,1U9XV@1239|Firmicutes,4IK5K@91061|Bacilli,1WH9X@129337|Geobacillus	91061|Bacilli	S	Tissue inhibitor of metalloproteinase	-	-	-	-	-	-	-	-	-	-	-	-	TIMP
SRR25158343_k127_1774492_45	1177179.A11A3_15950	1.241e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XKKE@135619|Oceanospirillales	135619|Oceanospirillales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158343_k127_1807077_1	714943.Mucpa_4701	2.358e-11	67.0	COG2963@1|root,COG2963@2|Bacteria,4NXP9@976|Bacteroidetes	976|Bacteroidetes	L	Transposase is3 is911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158343_k127_1807077_0	1166018.FAES_pFAES01008	8.653e-67	239.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,47MKZ@768503|Cytophagia	976|Bacteroidetes	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158343_k127_1811752_4	234267.Acid_3565	1.241e-164	565.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	ASH,CarboxypepD_reg,DUF11,FlgD_ig,HYR,Laminin_G_3,Plug,TonB_dep_Rec
SRR25158343_k127_1811752_28	240292.Ava_3538	8.01e-18	95.0	COG1876@1|root,COG1876@2|Bacteria,1G4P0@1117|Cyanobacteria,1HIMP@1161|Nostocales	1117|Cyanobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	-	-	-	-	-	-	-	-	-	-	VanY
SRR25158343_k127_1811752_29	886293.Sinac_0066	5.354e-17	92.0	COG3921@1|root,COG3921@2|Bacteria,2J1YT@203682|Planctomycetes	203682|Planctomycetes	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158343_k127_1811752_25	497964.CfE428DRAFT_4882	6.202e-31	142.0	2F6CM@1|root,33YVZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_23	1089550.ATTH01000001_gene2408	3.843e-37	158.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	2.3.1.43	ko:K00650	ko00564,ko04979,map00564,map04979	-	R02114	RC00037,RC00055	ko00000,ko00001,ko01000	-	-	-	DUF900,LCAT,Peptidase_C14
SRR25158343_k127_1811752_7	880073.Calab_0874	2.657e-135	440.0	COG0823@1|root,COG0823@2|Bacteria,2NQA4@2323|unclassified Bacteria	2|Bacteria	U	Periplasmic component of the Tol biopolymer transport system	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158343_k127_1811752_19	1122138.AQUZ01000002_gene1969	5.14e-41	162.0	28MYG@1|root,2ZB5C@2|Bacteria,2H19V@201174|Actinobacteria,4DU2K@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_17	1123508.JH636444_gene5476	9.09e-45	182.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SRR25158343_k127_1811752_6	1191523.MROS_0721	4.618e-136	443.0	COG1932@1|root,COG1932@2|Bacteria	2|Bacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158343_k127_1811752_12	485918.Cpin_4109	2.218e-73	255.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1IS17@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158343_k127_1811752_26	349521.HCH_06804	1.415e-28	122.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,1S2KT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_24	504472.Slin_2289	1.118e-32	133.0	COG0561@1|root,COG0561@2|Bacteria,4PKY8@976|Bacteroidetes,47YA2@768503|Cytophagia	976|Bacteroidetes	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_31	68199.JNZO01000046_gene6533	4.498e-16	91.0	2A1WW@1|root,30Q6B@2|Bacteria,2HGNT@201174|Actinobacteria	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158343_k127_1811752_32	573370.DMR_29500	3.397e-08	63.0	2AHBB@1|root,317MS@2|Bacteria,1PYZA@1224|Proteobacteria,435MG@68525|delta/epsilon subdivisions,2X00F@28221|Deltaproteobacteria,2M9DY@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_13	1123277.KB893196_gene4991	8.912e-73	254.0	COG0664@1|root,COG0664@2|Bacteria,4PM2A@976|Bacteroidetes,47KHT@768503|Cytophagia	976|Bacteroidetes	T	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158343_k127_1811752_21	1123508.JH636440_gene2572	1.327e-39	153.0	COG4319@1|root,COG4319@2|Bacteria,2J3B0@203682|Planctomycetes	203682|Planctomycetes	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158343_k127_1811752_10	926554.KI912657_gene4365	3.799e-94	317.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K06212,ko:K21990,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.4	-	-	Form_Nir_trans
SRR25158343_k127_1811752_15	927677.ALVU02000001_gene3277	1.75e-58	207.0	COG3871@1|root,COG3871@2|Bacteria,1GBSH@1117|Cyanobacteria	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
SRR25158343_k127_1811752_14	1408473.JHXO01000006_gene1219	7.153e-68	243.0	COG3291@1|root,COG3291@2|Bacteria,4NJR6@976|Bacteroidetes,2FX54@200643|Bacteroidia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_5	1320556.AVBP01000012_gene3572	3.25e-143	464.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
SRR25158343_k127_1811752_11	1297742.A176_01568	2.157e-80	281.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,43C12@68525|delta/epsilon subdivisions,2WXMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158343_k127_1811752_2	56107.Cylst_4051	1.106e-198	627.0	COG0477@1|root,COG2814@2|Bacteria,1G0BP@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158343_k127_1811752_16	105559.Nwat_1048	9.595e-53	193.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,1S3IM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158343_k127_1811752_9	1121957.ATVL01000008_gene4646	6.913e-101	366.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158343_k127_1811752_0	1121481.AUAS01000005_gene1783	0.0	1025.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
SRR25158343_k127_1811752_20	273068.TTE2189	7.34e-40	151.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,42GHI@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158343_k127_1811752_18	1120985.AUMI01000014_gene749	3.038e-42	170.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4H1VN@909932|Negativicutes	909932|Negativicutes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	AMIN,NAGPA
SRR25158343_k127_1811752_8	1340493.JNIF01000003_gene2831	5.554e-126	419.0	COG0415@1|root,COG0415@2|Bacteria,3Y31R@57723|Acidobacteria	57723|Acidobacteria	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158343_k127_1811752_27	215803.DB30_5360	2.242e-23	106.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_22	211165.AJLN01000081_gene1030	7.806e-39	152.0	29GXU@1|root,303VH@2|Bacteria,1G7X1@1117|Cyanobacteria,1JKDB@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1811752_30	573370.DMR_27510	1.218e-16	87.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158343_k127_1811752_1	278963.ATWD01000001_gene3278	2.301e-276	894.0	COG1629@1|root,COG4771@2|Bacteria,3Y3SA@57723|Acidobacteria,2JIYD@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_1811752_3	204669.Acid345_2229	4.763e-165	545.0	COG0308@1|root,COG0308@2|Bacteria,3Y7E9@57723|Acidobacteria,2JMED@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_1830255_204	1300150.EMQU_2698	7.884e-05	45.0	2DYD9@1|root,3497U@2|Bacteria,1VYPW@1239|Firmicutes,4HZAC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_192	1229276.DI53_1797	5.089e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158343_k127_1830255_74	1123376.AUIU01000013_gene1724	1.66e-69	255.0	COG0815@1|root,COG0815@2|Bacteria,3J0HA@40117|Nitrospirae	40117|Nitrospirae	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158343_k127_1830255_30	1158318.ATXC01000001_gene1139	9.12e-122	400.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158343_k127_1830255_10	234267.Acid_5065	8.687e-178	587.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria	57723|Acidobacteria	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158343_k127_1830255_168	941824.TCEL_02014	4.942e-13	73.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,36KSY@31979|Clostridiaceae	186801|Clostridia	L	Competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158343_k127_1830255_153	697303.Thewi_1030	1.459e-18	99.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,42F11@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158343_k127_1830255_161	1300345.LF41_2410	1.477e-15	83.0	COG2197@1|root,COG2197@2|Bacteria,1NA3X@1224|Proteobacteria	1224|Proteobacteria	KT	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
SRR25158343_k127_1830255_185	1267535.KB906767_gene4714	7.086e-07	59.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_171	1123325.JHUV01000012_gene1034	6.502e-11	74.0	COG3267@1|root,COG3267@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,SPOR
SRR25158343_k127_1830255_170	1123284.KB899064_gene941	2.525e-12	80.0	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,4HCUT@91061|Bacilli	91061|Bacilli	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR25158343_k127_1830255_207	1238450.VIBNISOn1_1570007	0.0001742	47.0	COG1414@1|root,COG1414@2|Bacteria,1PGPN@1224|Proteobacteria,1RRGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158343_k127_1830255_212	999423.HMPREF9161_00804	0.0008576	48.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158343_k127_1830255_205	318464.IO99_00420	9.713e-05	50.0	COG2856@1|root,COG2856@2|Bacteria,1VEWS@1239|Firmicutes,24R47@186801|Clostridia,36KJJ@31979|Clostridiaceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158343_k127_1830255_154	1341151.ASZU01000003_gene2417	1.993e-18	90.0	COG1714@1|root,COG1714@2|Bacteria,1UWKF@1239|Firmicutes,4I2FF@91061|Bacilli,27CZI@186824|Thermoactinomycetaceae	91061|Bacilli	S	Domain of Unknown Function with PDB structure (DUF3862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3862
SRR25158343_k127_1830255_132	1033732.CAHI01000006_gene2209	6.026e-32	131.0	2DJV2@1|root,32UDX@2|Bacteria,4NTF7@976|Bacteroidetes,2FU8P@200643|Bacteroidia,22VEE@171550|Rikenellaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_134	1382359.JIAL01000001_gene1169	6.909e-29	134.0	COG4373@1|root,COG4373@2|Bacteria,3Y318@57723|Acidobacteria,2JIZZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Mu-like prophage FluMu protein gp28	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
SRR25158343_k127_1830255_89	443144.GM21_3671	4.635e-60	228.0	2DNRB@1|root,32YRN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_176	880073.Calab_1462	7.026e-10	70.0	2EREN@1|root,33J06@2|Bacteria,2NRBT@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
SRR25158343_k127_1830255_151	323097.Nham_2366	1.218e-18	92.0	2F6K9@1|root,33Z35@2|Bacteria,1NX6D@1224|Proteobacteria,2UTN0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_209	931276.Cspa_c26590	0.0003156	48.0	COG4249@1|root,COG4249@2|Bacteria,1VPQ5@1239|Firmicutes,24TS2@186801|Clostridia,36N4D@31979|Clostridiaceae	186801|Clostridia	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
SRR25158343_k127_1830255_182	537013.CLOSTMETH_01228	2.023e-08	66.0	28IS3@1|root,2Z8R9@2|Bacteria,1TSHH@1239|Firmicutes,24CQ6@186801|Clostridia,3WHGD@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR25158343_k127_1830255_147	883081.HMPREF9698_01109	1.992e-23	119.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,27GNM@186828|Carnobacteriaceae	91061|Bacilli	S	Phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR25158343_k127_1830255_197	102129.Lepto7375DRAFT_7301	3.683e-05	58.0	COG3941@1|root,COG4678@1|root,COG3941@2|Bacteria,COG4678@2|Bacteria,1G8BM@1117|Cyanobacteria,1HHG8@1150|Oscillatoriales	1117|Cyanobacteria	G	Muramidase (Phage lambda lysozyme)	-	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158343_k127_1830255_138	485918.Cpin_2448	5.235e-26	124.0	COG2133@1|root,COG3408@1|root,COG4935@1|root,COG2133@2|Bacteria,COG3408@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Big_4,Big_5,Inhibitor_I9,Metallophos,PA,PA14,Peptidase_M36,Peptidase_S8,SLH
SRR25158343_k127_1830255_157	243231.GSU1945	1.287e-16	94.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1Q4PP@1224|Proteobacteria,42YRG@68525|delta/epsilon subdivisions,2WUJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
SRR25158343_k127_1830255_101	1047013.AQSP01000135_gene1581	1.189e-50	197.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158343_k127_1830255_9	557598.LHK_03208	7.152e-180	578.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,2KPRT@206351|Neisseriales	206351|Neisseriales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158343_k127_1830255_184	926566.Terro_3176	5.652e-08	65.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	spoIVB	-	3.4.21.116,3.4.24.3	ko:K01387,ko:K06399	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	Peptidase_M61,Peptidase_M9,Peptidase_M9_N
SRR25158343_k127_1830255_160	204669.Acid345_4348	1.232e-15	89.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria,2JIYP@204432|Acidobacteriia	204432|Acidobacteriia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
SRR25158343_k127_1830255_141	1267535.KB906767_gene291	1.385e-25	109.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SRR25158343_k127_1830255_127	1499967.BAYZ01000170_gene5526	4.808e-36	139.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158343_k127_1830255_200	218284.CCDN010000001_gene445	4.3e-05	53.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
SRR25158343_k127_1830255_33	575540.Isop_1088	2.272e-117	385.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158343_k127_1830255_13	59374.Fisuc_2256	1.841e-156	498.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	uxs	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_1830255_38	1121104.AQXH01000001_gene2099	1.542e-111	389.0	COG1506@1|root,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1IPE8@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR25158343_k127_1830255_143	86416.Clopa_2098	2.194e-24	108.0	2A1FW@1|root,30PPA@2|Bacteria,1UA53@1239|Firmicutes,254CY@186801|Clostridia,36TYS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_82	880073.Calab_1949	2.016e-66	236.0	COG2503@1|root,COG2503@2|Bacteria	2|Bacteria	M	HAD superfamily, subfamily IIIB (Acid phosphatase)	lppC	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158343_k127_1830255_61	1173024.KI912150_gene1258	6.582e-87	292.0	COG1515@1|root,COG1515@2|Bacteria,1G2HF@1117|Cyanobacteria,1JHXD@1189|Stigonemataceae	1117|Cyanobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158343_k127_1830255_72	926550.CLDAP_16470	2.07e-71	252.0	COG1173@1|root,COG1173@2|Bacteria,2G612@200795|Chloroflexi	200795|Chloroflexi	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158343_k127_1830255_69	1499967.BAYZ01000095_gene4083	3.72e-76	266.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	iLJ478.TM1747	BPD_transp_1
SRR25158343_k127_1830255_97	1329516.JPST01000003_gene1038	3.078e-55	200.0	COG1413@1|root,COG1413@2|Bacteria,1UHU8@1239|Firmicutes,4HKJW@91061|Bacilli,27D0I@186824|Thermoactinomycetaceae	91061|Bacilli	C	Protein of unknown function (DUF4241)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241
SRR25158343_k127_1830255_48	935836.JAEL01000014_gene2027	7.961e-100	335.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus	91061|Bacilli	E	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158343_k127_1830255_39	246194.CHY_1126	1.374e-110	368.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,42F1U@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158343_k127_1830255_64	926550.CLDAP_16450	7.774e-81	291.0	COG4166@1|root,COG4166@2|Bacteria,2G81P@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158343_k127_1830255_2	436114.SYO3AOP1_0213	1.266e-243	767.0	COG1217@1|root,COG1217@2|Bacteria,2G4QC@200783|Aquificae	200783|Aquificae	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158343_k127_1830255_35	765420.OSCT_2288	2.425e-116	381.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,375BG@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158343_k127_1830255_121	1267535.KB906767_gene4845	9.266e-41	157.0	COG2823@1|root,COG2823@2|Bacteria,3Y4KR@57723|Acidobacteria,2JJBS@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158343_k127_1830255_162	1198114.AciX9_2169	1.244e-14	83.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_1830255_104	243231.GSU1197	6.862e-50	183.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WP0F@28221|Deltaproteobacteria,43SHY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158343_k127_1830255_183	234267.Acid_2436	3.059e-08	66.0	COG3170@1|root,COG3170@2|Bacteria,3Y4RX@57723|Acidobacteria	57723|Acidobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_117	682795.AciX8_2195	2.669e-43	166.0	COG1765@1|root,COG1765@2|Bacteria,3Y563@57723|Acidobacteria,2JJUX@204432|Acidobacteriia	204432|Acidobacteriia	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158343_k127_1830255_175	220664.PFL_5499	4.744e-10	66.0	2FIF7@1|root,34A7E@2|Bacteria,1P0Y3@1224|Proteobacteria,1SRS2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3828)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
SRR25158343_k127_1830255_188	1169161.KB897718_gene3245	1.078e-06	60.0	COG2214@1|root,COG2214@2|Bacteria,2GJ55@201174|Actinobacteria	201174|Actinobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_119	1280001.BAOA01000019_gene467	6.916e-41	153.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,1XXXM@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158343_k127_1830255_29	335543.Sfum_1332	1.858e-122	409.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,42SZH@68525|delta/epsilon subdivisions,2WPX7@28221|Deltaproteobacteria,2MQHU@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158343_k127_1830255_156	1122222.AXWR01000043_gene2580	8.865e-18	93.0	2DUZD@1|root,33T56@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_211	1380600.AUYN01000009_gene2114	0.0006472	48.0	2EVPN@1|root,33P3M@2|Bacteria,4NXTE@976|Bacteroidetes,1I6J4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_67	1210884.HG799463_gene9403	1.323e-79	271.0	COG3921@1|root,COG3921@2|Bacteria,2J1YT@203682|Planctomycetes	203682|Planctomycetes	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158343_k127_1830255_42	204669.Acid345_4150	2.941e-103	347.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_62	521674.Plim_3377	3.141e-86	291.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	ART,Macro
SRR25158343_k127_1830255_60	661478.OP10G_1466	6.723e-90	301.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091,ko:K05967,ko:K07025	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NT5C
SRR25158343_k127_1830255_136	1279009.ADICEAN_01131	1.478e-28	128.0	COG1216@1|root,COG1216@2|Bacteria,4NNEA@976|Bacteroidetes,47QNU@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_1830255_22	580332.Slit_1514	3.899e-136	443.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,44V3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158343_k127_1830255_111	268407.PWYN_25710	3.501e-46	171.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_1830255_190	522306.CAP2UW1_2189	2.897e-06	55.0	2E3TX@1|root,32YRB@2|Bacteria,1NAJY@1224|Proteobacteria,2VX3D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_45	1408813.AYMG01000023_gene2101	1.011e-101	345.0	COG2890@1|root,COG2890@2|Bacteria,4NH0Q@976|Bacteroidetes,1IUVK@117747|Sphingobacteriia	976|Bacteroidetes	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
SRR25158343_k127_1830255_189	944481.JAFP01000001_gene1396	1.418e-06	56.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M6K6@213113|Desulfurellales	28221|Deltaproteobacteria	M	Surface antigen	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158343_k127_1830255_87	93220.LV28_05210	1.343e-60	212.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2VRG8@28216|Betaproteobacteria,1K76N@119060|Burkholderiaceae	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158343_k127_1830255_66	1121904.ARBP01000006_gene3852	1.148e-80	280.0	COG0726@1|root,COG0726@2|Bacteria,4NKYS@976|Bacteroidetes,47NF6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	pgdA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158343_k127_1830255_43	234267.Acid_1867	3.786e-103	347.0	COG0665@1|root,COG0665@2|Bacteria,3Y5BS@57723|Acidobacteria	57723|Acidobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303,ko:K21061	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R00610,R11428	RC00060,RC00135,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158343_k127_1830255_55	1379698.RBG1_1C00001G1531	4.585e-92	312.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158343_k127_1830255_167	663278.Ethha_1083	9.752e-14	75.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158343_k127_1830255_71	518766.Rmar_1551	7.622e-72	251.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158343_k127_1830255_94	234267.Acid_1848	1.541e-57	216.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_1830255_208	1120980.JQKH01000014_gene783	0.0003055	52.0	COG3392@1|root,COG3392@2|Bacteria,1R84X@1224|Proteobacteria,2VYIJ@28216|Betaproteobacteria,2KS59@206351|Neisseriales	206351|Neisseriales	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	MethyltransfD12
SRR25158343_k127_1830255_130	485913.Krac_11148	5.771e-33	135.0	COG3437@1|root,COG3437@2|Bacteria,2GA97@200795|Chloroflexi	2|Bacteria	KT	Diguanylate cyclase and metal dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,MASE1
SRR25158343_k127_1830255_180	31033.ENSTRUP00000004926	1.154e-08	68.0	COG0484@1|root,KOG0722@2759|Eukaryota,38F65@33154|Opisthokonta,3B9N4@33208|Metazoa,3CVHM@33213|Bilateria,484ZE@7711|Chordata,48Z2M@7742|Vertebrata,49YGP@7898|Actinopterygii	33208|Metazoa	O	DnaJ (Hsp40) homolog, subfamily C , member 25	DNAJC25	-	-	ko:K19371	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ
SRR25158343_k127_1830255_163	316274.Haur_1019	1.26e-14	79.0	2F0X9@1|root,340RI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_115	1267535.KB906767_gene874	1.654e-44	171.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_31	1230343.CANP01000031_gene2394	1.828e-119	393.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JD3W@118969|Legionellales	118969|Legionellales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158343_k127_1830255_107	886293.Sinac_3762	2.05e-48	183.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,2IZ1I@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
SRR25158343_k127_1830255_5	234267.Acid_3719	8.443e-224	736.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158343_k127_1830255_6	2325.TKV_c05890	2.094e-204	656.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158343_k127_1830255_7	234267.Acid_1531	5.403e-184	591.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158343_k127_1830255_126	118168.MC7420_2192	1.118e-36	155.0	COG2027@1|root,COG2027@2|Bacteria,1G06E@1117|Cyanobacteria,1H79I@1150|Oscillatoriales	1117|Cyanobacteria	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158343_k127_1830255_125	439481.Aboo_0474	4.647e-37	148.0	COG1059@1|root,arCOG04357@2157|Archaea,2XWSZ@28890|Euryarchaeota,3F2WU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)	ogg	-	4.2.99.18	ko:K03653	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158343_k127_1830255_155	1151292.QEW_0036	2.936e-18	99.0	COG3577@1|root,COG5010@1|root,COG3577@2|Bacteria,COG5010@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	ko:K06985,ko:K07272,ko:K20543,ko:K21007	ko02025,ko04112,map02025,map04112	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	1.B.55.3	-	-	Asp_protease_2,TPR_8,gag-asp_proteas
SRR25158343_k127_1830255_148	272123.Anacy_2095	1.131e-21	100.0	COG1848@1|root,COG1848@2|Bacteria,1G8T6@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158343_k127_1830255_194	1408304.JAHA01000008_gene1879	5.975e-06	57.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,4BW8Z@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
SRR25158343_k127_1830255_142	1156937.MFUM_1010067	2.132e-25	112.0	COG0741@1|root,COG0741@2|Bacteria,46W79@74201|Verrucomicrobia,37GKP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158343_k127_1830255_50	574087.Acear_0510	1.67e-99	341.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3WB7T@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158343_k127_1830255_90	204669.Acid345_3047	4.919e-60	218.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,3Y5CC@57723|Acidobacteria,2JHX0@204432|Acidobacteriia	204432|Acidobacteriia	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
SRR25158343_k127_1830255_144	316274.Haur_3076	4.168e-24	119.0	COG0741@1|root,COG1729@1|root,COG4105@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,2G6NM@200795|Chloroflexi,374VP@32061|Chloroflexia	32061|Chloroflexia	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
SRR25158343_k127_1830255_181	411477.PARMER_01374	1.775e-08	68.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,22X5K@171551|Porphyromonadaceae	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
SRR25158343_k127_1830255_41	639030.JHVA01000001_gene2145	2.606e-105	350.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JIT2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158343_k127_1830255_113	935567.JAES01000029_gene2759	1.33e-45	174.0	2ASN4@1|root,31I2V@2|Bacteria,1QFS0@1224|Proteobacteria,1TD1J@1236|Gammaproteobacteria,1X9WY@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_105	234267.Acid_4781	5.57e-49	181.0	COG0237@1|root,COG0237@2|Bacteria,3Y4R2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158343_k127_1830255_92	314287.GB2207_02287	1.173e-58	226.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1J6HF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158343_k127_1830255_52	251221.35214700	4.173e-98	348.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158343_k127_1830255_51	251221.35214699	4.096e-98	329.0	COG0601@1|root,COG0601@2|Bacteria,1G01A@1117|Cyanobacteria	1117|Cyanobacteria	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K15581,ko:K15585	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158343_k127_1830255_57	251221.35214698	9.156e-91	312.0	COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158343_k127_1830255_26	251221.35214697	3.266e-130	424.0	COG0444@1|root,COG0444@2|Bacteria,1G1NU@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158343_k127_1830255_25	765420.OSCT_0589	2.75e-130	424.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158343_k127_1830255_109	1380394.JADL01000011_gene3927	6.644e-47	173.0	COG1633@1|root,COG1633@2|Bacteria,1RGZG@1224|Proteobacteria,2UC9G@28211|Alphaproteobacteria,2JUTX@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
SRR25158343_k127_1830255_65	1184267.A11Q_2474	8.714e-81	273.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,439YB@68525|delta/epsilon subdivisions,2MTVS@213481|Bdellovibrionales,2X23X@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158343_k127_1830255_80	1125863.JAFN01000001_gene381	1.836e-66	252.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SRR25158343_k127_1830255_165	487796.Flav2ADRAFT_1527	2.516e-14	87.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158343_k127_1830255_177	487796.Flav2ADRAFT_1528	2.217e-09	63.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158343_k127_1830255_112	1094508.Tsac_0612	5.71e-46	182.0	COG2203@1|root,COG2206@1|root,COG3850@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3850@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42GDE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HAMP,HD,HD_5,PAS_9,PocR,Response_reg
SRR25158343_k127_1830255_70	292459.STH2676	5.123e-75	261.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21900	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158343_k127_1830255_114	292459.STH3176	6.098e-45	171.0	COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,24M03@186801|Clostridia	186801|Clostridia	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158343_k127_1830255_1	986075.CathTA2_1520	8.983e-273	853.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli	91061|Bacilli	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05640	FAD_binding_2,Succ_DH_flav_C
SRR25158343_k127_1830255_54	1034809.SLUG_17290	7.698e-95	317.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,4GX8N@90964|Staphylococcaceae	91061|Bacilli	C	succinate dehydrogenase	sdhB	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
SRR25158343_k127_1830255_11	1379698.RBG1_1C00001G0607	1.485e-176	580.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158343_k127_1830255_21	439235.Dalk_0818	1.584e-138	446.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158343_k127_1830255_8	1183438.GKIL_3395	1.915e-180	602.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_1830255_93	234267.Acid_1209	1.518e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_1830255_139	203122.Sde_0642	5.665e-26	117.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR25158343_k127_1830255_191	1382359.JIAL01000001_gene1533	4.233e-06	58.0	28MS6@1|root,2ZB0K@2|Bacteria,3Y38I@57723|Acidobacteria,2JHU5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_174	1382359.JIAL01000001_gene753	4.038e-10	68.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria,2JP08@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_166	32057.KB217478_gene3083	2.895e-14	78.0	COG5499@1|root,COG5499@2|Bacteria,1G6YN@1117|Cyanobacteria,1HNWU@1161|Nostocales	1117|Cyanobacteria	K	COGs COG5499 transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
SRR25158343_k127_1830255_0	1223410.KN050846_gene226	4.605e-321	1008.0	COG1061@1|root,COG1061@2|Bacteria,4NT3R@976|Bacteroidetes,1I4VZ@117743|Flavobacteriia	976|Bacteroidetes	KL	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
SRR25158343_k127_1830255_102	96561.Dole_2560	1.713e-50	184.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria,2MKC1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
SRR25158343_k127_1830255_4	411459.RUMOBE_00678	2.721e-231	734.0	COG2189@1|root,COG2189@2|Bacteria,1UVF7@1239|Firmicutes,25MPZ@186801|Clostridia,3Y23W@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158343_k127_1830255_187	632245.CLP_0113	8.653e-07	61.0	COG2865@1|root,COG2865@2|Bacteria,1UZZK@1239|Firmicutes,25CHX@186801|Clostridia,36EY6@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR25158343_k127_1830255_195	1487923.DP73_14315	1.043e-05	51.0	COG4636@1|root,COG4636@2|Bacteria,1V3G7@1239|Firmicutes,24H2Z@186801|Clostridia,266ZP@186807|Peptococcaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Uma2
SRR25158343_k127_1830255_149	68199.JNZO01000025_gene5851	1.935e-21	109.0	COG0358@1|root,COG0358@2|Bacteria,2IF71@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_3
SRR25158343_k127_1830255_34	1123277.KB893212_gene9	1.352e-116	396.0	COG2197@1|root,COG2197@2|Bacteria,4NES9@976|Bacteroidetes,47NH3@768503|Cytophagia	976|Bacteroidetes	KT	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,GerE,HTH_23
SRR25158343_k127_1830255_68	1121468.AUBR01000053_gene1603	7.774e-79	276.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42F9X@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158343_k127_1830255_152	416591.Tlet_1601	1.347e-18	91.0	COG1585@1|root,COG1585@2|Bacteria,2GDCD@200918|Thermotogae	200918|Thermotogae	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158343_k127_1830255_100	379066.GAU_0938	1.071e-51	195.0	COG0631@1|root,COG0631@2|Bacteria,1ZT1X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158343_k127_1830255_12	240015.ACP_1006	6.312e-161	514.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158343_k127_1830255_46	639030.JHVA01000001_gene3583	1.555e-100	336.0	COG0583@1|root,COG0583@2|Bacteria,3Y31P@57723|Acidobacteria,2JIC0@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158343_k127_1830255_19	945713.IALB_1286	2.513e-145	469.0	COG2170@1|root,COG2170@2|Bacteria	2|Bacteria	S	glutamate-cysteine ligase activity	ybdK	GO:0003674,GO:0003824,GO:0016874,GO:0016879	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158343_k127_1830255_77	1278073.MYSTI_03644	1.642e-67	239.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,42WI7@68525|delta/epsilon subdivisions,2WSAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158343_k127_1830255_158	706587.Desti_4587	3.473e-16	89.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,42SRU@68525|delta/epsilon subdivisions,2WPAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	guaA2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR25158343_k127_1830255_106	1123278.KB893389_gene4175	1.026e-48	178.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,47RTX@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158343_k127_1830255_32	443143.GM18_4377	6.475e-118	396.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158343_k127_1830255_14	880072.Desac_2105	1.936e-156	510.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158343_k127_1830255_15	925409.KI911562_gene202	9.177e-155	515.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158343_k127_1830255_129	404380.Gbem_3916	4.443e-33	131.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,43V3G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158343_k127_1830255_137	237368.SCABRO_02001	2.055e-28	121.0	COG0839@1|root,COG0839@2|Bacteria,2J0MC@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158343_k127_1830255_40	240015.ACP_0289	1.991e-106	356.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158343_k127_1830255_24	1267535.KB906767_gene4284	1.275e-130	445.0	COG3383@1|root,COG3383@2|Bacteria,3Y2T6@57723|Acidobacteria,2JIAG@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_10,Fer4_6,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRR25158343_k127_1830255_17	1121373.KB903623_gene2360	1.545e-149	485.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,47NNF@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRR25158343_k127_1830255_131	1121028.ARQE01000007_gene3787	7.095e-33	132.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,2UGFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158343_k127_1830255_120	1121028.ARQE01000007_gene3787	7.028e-41	154.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,2UGFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158343_k127_1830255_108	491205.JARQ01000011_gene1325	2.771e-47	175.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1HZPI@117743|Flavobacteriia,3ZQR9@59732|Chryseobacterium	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158343_k127_1830255_16	316067.Geob_0465	3.416e-153	493.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
SRR25158343_k127_1830255_116	1232410.KI421424_gene1782	4.625e-44	165.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2WQB1@28221|Deltaproteobacteria,43UPG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SRR25158343_k127_1830255_73	1122182.KB903813_gene2325	4.287e-70	243.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4D8NQ@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158343_k127_1830255_133	247490.KSU1_D0329	1.638e-30	126.0	COG0838@1|root,COG0838@2|Bacteria,2J09T@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158343_k127_1830255_173	903818.KI912269_gene353	2.896e-10	71.0	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_169	768670.Calni_0069	1.703e-12	69.0	COG2104@1|root,COG2104@2|Bacteria,2GG4I@200930|Deferribacteres	200930|Deferribacteres	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158343_k127_1830255_49	1340493.JNIF01000003_gene2305	1.075e-99	332.0	COG2022@1|root,COG2022@2|Bacteria,3Y2YY@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158343_k127_1830255_196	1122927.KB895413_gene1783	1.535e-05	53.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,26ZR6@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccB	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SRR25158343_k127_1830255_59	1444711.CCJF01000004_gene2434	1.524e-90	306.0	COG1090@1|root,COG1090@2|Bacteria,2JFV6@204428|Chlamydiae	204428|Chlamydiae	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158343_k127_1830255_122	401053.AciPR4_4209	4.6e-40	149.0	COG5207@1|root,COG5207@2|Bacteria,3Y5QE@57723|Acidobacteria	57723|Acidobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158343_k127_1830255_140	1120949.KB903312_gene613	8.651e-26	113.0	COG1959@1|root,COG1959@2|Bacteria,2IFDS@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158343_k127_1830255_99	926556.Echvi_0101	1.115e-52	192.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,47PPH@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
SRR25158343_k127_1830255_53	929703.KE386491_gene1241	9.701e-97	323.0	COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,47KW5@768503|Cytophagia	976|Bacteroidetes	S	PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158343_k127_1830255_28	1173024.KI912148_gene4321	1.197e-122	402.0	COG0604@1|root,COG0604@2|Bacteria,1G241@1117|Cyanobacteria,1JHGA@1189|Stigonemataceae	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158343_k127_1830255_135	861299.J421_0551	1.258e-28	117.0	2DNQD@1|root,32YJR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
SRR25158343_k127_1830255_79	761193.Runsl_0668	9.876e-67	234.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158343_k127_1830255_91	1189619.pgond44_11351	1.373e-59	220.0	2DBJ5@1|root,2Z9IG@2|Bacteria,4NI72@976|Bacteroidetes,1I06W@117743|Flavobacteriia,4C4A8@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_123	1384054.N790_09330	6.091e-38	146.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,1S8M3@1236|Gammaproteobacteria,1XAU1@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158343_k127_1830255_81	202952.BBLI01000013_gene1242	1.959e-66	234.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S4YD@1236|Gammaproteobacteria,3NKR3@468|Moraxellaceae	1236|Gammaproteobacteria	O	Glutathione peroxidase	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158343_k127_1830255_75	1541065.JRFE01000014_gene1536	8.528e-69	237.0	COG3576@1|root,COG3576@2|Bacteria,1G5D9@1117|Cyanobacteria,3VJJD@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158343_k127_1830255_44	1284352.AOIG01000008_gene2344	9.739e-102	339.0	COG0667@1|root,COG0667@2|Bacteria,1V300@1239|Firmicutes,4HERM@91061|Bacilli,26TBI@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_1830255_20	443144.GM21_2083	6.916e-143	462.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158343_k127_1830255_27	204773.HEAR3454	1.757e-127	416.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,473M9@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Luciferase-like monooxygenase	limB	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158343_k127_1830255_98	362418.IW19_00770	1.42e-53	193.0	COG1225@1|root,COG1225@2|Bacteria,4NMGU@976|Bacteroidetes,1I1JH@117743|Flavobacteriia,2NW0W@237|Flavobacterium	976|Bacteroidetes	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158343_k127_1830255_95	1459636.NTE_01147	1.705e-57	205.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158343_k127_1830255_88	929713.NIASO_14915	3.027e-60	212.0	COG1670@1|root,COG1670@2|Bacteria,4NNZ3@976|Bacteroidetes,1IY9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158343_k127_1830255_56	1382306.JNIM01000001_gene2538	4.106e-91	310.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158343_k127_1830255_83	566466.NOR53_177	6.849e-64	227.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,1SKH6@1236|Gammaproteobacteria,1J7J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_1830255_159	861299.J421_0675	5.323e-16	81.0	COG0640@1|root,COG0640@2|Bacteria,1ZV8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
SRR25158343_k127_1830255_47	886293.Sinac_1873	4.47e-100	332.0	COG1028@1|root,COG1028@2|Bacteria,2IZED@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_1830255_96	1185876.BN8_06700	1.51e-55	201.0	COG2085@1|root,COG2085@2|Bacteria,4NEC7@976|Bacteroidetes,47QUG@768503|Cytophagia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158343_k127_1830255_78	1487953.JMKF01000026_gene1438	4.532e-67	239.0	COG0451@1|root,COG0451@2|Bacteria,1G48F@1117|Cyanobacteria,1H82K@1150|Oscillatoriales	1117|Cyanobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158343_k127_1830255_37	714943.Mucpa_4043	4.539e-113	371.0	COG4221@1|root,COG4221@2|Bacteria,4NF39@976|Bacteroidetes,1IQ7S@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_1830255_18	1227739.Hsw_1849	1.895e-149	479.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47TTT@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_1830255_23	1298608.JCM18900_12056	3.251e-131	426.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,3NJRZ@468|Moraxellaceae	1236|Gammaproteobacteria	S	Alcohol dehydrogenase GroES-like domain	yjgB	GO:0003674,GO:0003824,GO:0004033,GO:0005488,GO:0008106,GO:0008150,GO:0008152,GO:0008270,GO:0016491,GO:0016614,GO:0016616,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158343_k127_1830255_179	221288.JH992901_gene4739	7.581e-09	59.0	COG1359@1|root,COG1359@2|Bacteria,1GAAJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158343_k127_1830255_118	485913.Krac_3335	7.314e-43	161.0	COG1764@1|root,COG1764@2|Bacteria,2G6W8@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158343_k127_1830255_128	365046.Rta_23420	5.831e-36	139.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,4AE6H@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158343_k127_1830255_63	1177181.T9A_00473	3.56e-86	297.0	COG2357@1|root,COG2357@2|Bacteria,1RDE9@1224|Proteobacteria,1RQJM@1236|Gammaproteobacteria,1XPUZ@135619|Oceanospirillales	135619|Oceanospirillales	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
SRR25158343_k127_1830255_3	1379270.AUXF01000004_gene3330	8.571e-235	742.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SRR25158343_k127_1830255_85	868595.Desca_1025	5.16e-62	223.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,260YT@186807|Peptococcaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158343_k127_1830255_103	204669.Acid345_4380	3.546e-50	202.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,3Y89N@57723|Acidobacteria	57723|Acidobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SRR25158343_k127_1830255_124	1158345.JNLL01000001_gene799	2.066e-37	149.0	COG0352@1|root,COG0352@2|Bacteria,2G51J@200783|Aquificae	200783|Aquificae	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE1	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158343_k127_1830255_84	525904.Tter_0647	1.21e-62	225.0	COG0351@1|root,COG0351@2|Bacteria,2NP3M@2323|unclassified Bacteria	2|Bacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00868,ko:K00941,ko:K03147,ko:K21219	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS03115	Phos_pyr_kin
SRR25158343_k127_1830255_178	1379698.RBG1_1C00001G0758	4.26e-09	67.0	2ER9F@1|root,33IV2@2|Bacteria,2NRV9@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1830255_110	1123248.KB893314_gene3458	2.311e-46	173.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1ITIY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SRR25158343_k127_1830255_86	1329516.JPST01000005_gene1351	7.421e-61	221.0	COG3253@1|root,COG3253@2|Bacteria,1VZPB@1239|Firmicutes,4HZ7E@91061|Bacilli,27B36@186824|Thermoactinomycetaceae	91061|Bacilli	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158343_k127_1830255_164	234267.Acid_7268	2.515e-14	76.0	COG1254@1|root,COG1254@2|Bacteria,3Y55N@57723|Acidobacteria	57723|Acidobacteria	C	acylphosphatase activity	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158343_k127_1830255_76	234267.Acid_7098	4.725e-68	235.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158343_k127_1830255_36	756067.MicvaDRAFT_1203	1.409e-115	387.0	COG3664@1|root,COG3664@2|Bacteria,1G06Z@1117|Cyanobacteria,1HA6V@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
SRR25158343_k127_1848968_63	1173027.Mic7113_5132	1.283e-105	350.0	COG0037@1|root,COG0037@2|Bacteria,1G2S7@1117|Cyanobacteria,1H8M3@1150|Oscillatoriales	1117|Cyanobacteria	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	-	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
SRR25158343_k127_1848968_24	234267.Acid_0475	1.752e-171	543.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158343_k127_1848968_122	489825.LYNGBM3L_53820	5.946e-51	183.0	COG0073@1|root,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10,6.1.1.20,6.1.1.6	ko:K01874,ko:K01890,ko:K04566,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03658,R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,B5,tRNA-synt_1f,tRNA-synt_1g,tRNA_bind
SRR25158343_k127_1848968_178	314285.KT71_08977	1.616e-19	94.0	COG0454@1|root,COG0456@2|Bacteria,1PF78@1224|Proteobacteria,1TBZZ@1236|Gammaproteobacteria,1JBPP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_48	666686.B1NLA3E_07420	5.581e-128	447.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,1V255@1239|Firmicutes,4HFUF@91061|Bacilli,1ZI0D@1386|Bacillus	91061|Bacilli	M	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Cytochrom_D1,Lactonase,Phosphoesterase
SRR25158343_k127_1848968_183	383372.Rcas_0309	3.831e-17	84.0	2EJQK@1|root,33DFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_17	344747.PM8797T_10559	1.716e-194	612.0	COG0156@1|root,COG0156@2|Bacteria,2IX0H@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_1848968_172	1303518.CCALI_00309	1.787e-21	102.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	DSPc,DUF442,PTPlike_phytase,Y_phosphatase2,Y_phosphatase3
SRR25158343_k127_1848968_193	1049564.TevJSym_az00020	8.45e-10	69.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,1RQXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
SRR25158343_k127_1848968_133	234267.Acid_0084	1.031e-47	184.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_130	1267534.KB906759_gene1703	2.958e-48	185.0	2EZNS@1|root,33STS@2|Bacteria,3Y75C@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_13	326427.Cagg_3471	2.414e-215	690.0	COG0855@1|root,COG0855@2|Bacteria,2G68J@200795|Chloroflexi,374Y0@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158343_k127_1848968_123	1242864.D187_008829	6.021e-51	184.0	COG1917@1|root,COG1917@2|Bacteria,1N222@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_1848968_207	224911.27352980	5.017e-05	54.0	2DR2Z@1|root,339YC@2|Bacteria,1R9Q5@1224|Proteobacteria,2TUVJ@28211|Alphaproteobacteria,3JTUZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3828)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
SRR25158343_k127_1848968_14	886293.Sinac_5685	7.009e-212	676.0	COG0308@1|root,COG0308@2|Bacteria,2J268@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158343_k127_1848968_153	756067.MicvaDRAFT_5266	1.727e-36	143.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria,1HBXY@1150|Oscillatoriales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158343_k127_1848968_150	1286632.P278_00970	5.305e-39	154.0	COG3485@1|root,COG3485@2|Bacteria,4NRRC@976|Bacteroidetes,1I3NS@117743|Flavobacteriia	976|Bacteroidetes	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158343_k127_1848968_147	234267.Acid_4096	9.375e-40	154.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_1848968_137	661478.OP10G_0672	5.51e-45	179.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158343_k127_1848968_88	234267.Acid_4621	1.031e-74	266.0	29ZE1@1|root,30MD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_51	1191523.MROS_0722	6.437e-126	415.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
SRR25158343_k127_1848968_181	42256.RradSPS_1816	7.326e-19	90.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158343_k127_1848968_111	373994.Riv7116_4608	2.56e-57	201.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158343_k127_1848968_1	883096.HMPREF9699_00377	0.0	1260.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
SRR25158343_k127_1848968_38	575590.HMPREF0156_01070	2.256e-142	460.0	arCOG06431@1|root,2ZA78@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_41	575590.HMPREF0156_01071	4.726e-135	433.0	COG0338@1|root,COG0338@2|Bacteria,4NIEI@976|Bacteroidetes	976|Bacteroidetes	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158343_k127_1848968_56	1173022.Cri9333_0734	3.145e-116	381.0	COG0702@1|root,COG0702@2|Bacteria,1GEDH@1117|Cyanobacteria	1117|Cyanobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158343_k127_1848968_52	1229487.AMYW01000004_gene2170	3.727e-122	398.0	COG2819@1|root,COG2819@2|Bacteria,4NGAG@976|Bacteroidetes,1HZR3@117743|Flavobacteriia,2NVA2@237|Flavobacterium	976|Bacteroidetes	S	esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158343_k127_1848968_66	1392489.JPOL01000002_gene364	1.924e-98	326.0	COG0428@1|root,COG0428@2|Bacteria,4NHR7@976|Bacteroidetes,1HZWS@117743|Flavobacteriia,2XI89@283735|Leeuwenhoekiella	976|Bacteroidetes	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
SRR25158343_k127_1848968_134	929713.NIASO_07760	1.469e-47	174.0	COG0607@1|root,COG0607@2|Bacteria,4P495@976|Bacteroidetes,1IYNV@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158343_k127_1848968_83	760192.Halhy_0526	1.625e-83	286.0	28WFG@1|root,2ZIFP@2|Bacteria,4NN2N@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_165	298655.KI912267_gene7424	4.27e-24	106.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158343_k127_1848968_3	1121104.AQXH01000004_gene69	0.0	1208.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1IQZ2@117747|Sphingobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158343_k127_1848968_115	1123248.KB893359_gene2191	2.052e-55	196.0	COG5579@1|root,COG5579@2|Bacteria,4NTDS@976|Bacteroidetes,1IT7C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,DUF1810
SRR25158343_k127_1848968_205	879310.HMPREF9162_2339	1.004e-05	51.0	2ED5D@1|root,33725@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF3601)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3601
SRR25158343_k127_1848968_12	1492738.FEM21_09520	2.317e-224	706.0	COG0397@1|root,COG0397@2|Bacteria,4NEIV@976|Bacteroidetes,1HXHE@117743|Flavobacteriia,2NUN0@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
SRR25158343_k127_1848968_110	1189620.AJXL01000173_gene2619	5.166e-58	211.0	2CT8A@1|root,32SST@2|Bacteria,4NSUB@976|Bacteroidetes,1I4F3@117743|Flavobacteriia,2NYJ7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_58	760192.Halhy_0957	2.847e-109	366.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
SRR25158343_k127_1848968_103	344747.PM8797T_05665	5.574e-65	226.0	COG0041@1|root,COG0041@2|Bacteria,2IZNG@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158343_k127_1848968_85	351160.LRC130	4.164e-75	258.0	COG4912@1|root,arCOG11010@2157|Archaea,2XWKG@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158343_k127_1848968_32	1267535.KB906767_gene2202	1.074e-150	484.0	COG0026@1|root,COG0026@2|Bacteria,3Y3RI@57723|Acidobacteria,2JHQJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158343_k127_1848968_127	452637.Oter_3517	7.45e-50	196.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158343_k127_1848968_168	756499.Desde_1153	2.234e-23	105.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,24QSV@186801|Clostridia,262VX@186807|Peptococcaceae	186801|Clostridia	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158343_k127_1848968_77	215803.DB30_5632	9.051e-90	304.0	COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,438ZF@68525|delta/epsilon subdivisions,2X44Q@28221|Deltaproteobacteria,2YY90@29|Myxococcales	28221|Deltaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
SRR25158343_k127_1848968_121	1267535.KB906767_gene1426	3.214e-51	189.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
SRR25158343_k127_1848968_118	1185876.BN8_04261	6.361e-54	193.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158343_k127_1848968_125	143224.JQMD01000002_gene2485	1.166e-50	191.0	COG0596@1|root,COG0596@2|Bacteria,4NY3Z@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158343_k127_1848968_55	1449065.JMLL01000001_gene4031	1.357e-118	389.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,2TURU@28211|Alphaproteobacteria,43J77@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
SRR25158343_k127_1848968_31	420662.Mpe_A0328	1.737e-152	489.0	COG2519@1|root,COG2519@2|Bacteria,1QWVH@1224|Proteobacteria,2WH1E@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158343_k127_1848968_108	1183438.GKIL_3942	1.518e-58	209.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158343_k127_1848968_95	204669.Acid345_2219	7.671e-73	277.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y9GC@57723|Acidobacteria,2JKTW@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158343_k127_1848968_46	1295642.H839_13479	6.049e-132	429.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,1WFMJ@129337|Geobacillus	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158343_k127_1848968_143	926560.KE387023_gene1232	1.049e-41	159.0	2E2F3@1|root,32XJG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_90	1502852.FG94_01154	5.404e-74	261.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,475FS@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158343_k127_1848968_117	574087.Acear_1859	2.665e-54	201.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WBB0@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158343_k127_1848968_54	1254432.SCE1572_44415	9.302e-120	399.0	COG1404@1|root,COG1404@2|Bacteria,1PEJJ@1224|Proteobacteria,438RE@68525|delta/epsilon subdivisions,2X3YD@28221|Deltaproteobacteria,2YXKA@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158343_k127_1848968_124	1304875.JAFZ01000002_gene336	7.509e-51	190.0	COG1752@1|root,COG1752@2|Bacteria,3TC9C@508458|Synergistetes	508458|Synergistetes	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158343_k127_1848968_53	290512.Paes_0606	1.751e-121	399.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
SRR25158343_k127_1848968_23	237368.SCABRO_01667	2.945e-172	560.0	COG3930@1|root,COG3930@2|Bacteria,2J4QT@203682|Planctomycetes	203682|Planctomycetes	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
SRR25158343_k127_1848968_70	237368.SCABRO_01668	7.611e-96	321.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
SRR25158343_k127_1848968_45	204669.Acid345_4480	2.896e-132	439.0	COG1807@1|root,COG1807@2|Bacteria,3Y383@57723|Acidobacteria,2JIBE@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_1848968_194	1340493.JNIF01000003_gene3328	1.829e-09	69.0	COG0457@1|root,COG0457@2|Bacteria	1340493.JNIF01000003_gene3328|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_217	1229487.AMYW01000018_gene4152	0.0008914	51.0	COG1629@1|root,COG4771@2|Bacteria,4NET0@976|Bacteroidetes,1HY46@117743|Flavobacteriia,2NTGY@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	hmuR	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158343_k127_1848968_25	1519464.HY22_10885	1.39e-170	544.0	COG0282@1|root,COG0282@2|Bacteria,1FDWK@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158343_k127_1848968_60	485918.Cpin_5355	9.48e-109	355.0	COG0655@1|root,COG0655@2|Bacteria,4NMBJ@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158343_k127_1848968_93	1254432.SCE1572_26545	3.159e-73	259.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158343_k127_1848968_91	1267535.KB906767_gene1118	1.368e-73	257.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158343_k127_1848968_119	880073.Calab_3278	2.593e-53	205.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
SRR25158343_k127_1848968_29	234267.Acid_4393	7.311e-158	530.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_82	1242864.D187_009224	2.4e-85	307.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria	1224|Proteobacteria	E	peptidase	ptpA_2	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
SRR25158343_k127_1848968_11	1128421.JAGA01000003_gene3542	1.266e-227	716.0	COG1233@1|root,COG1233@2|Bacteria,2NQPV@2323|unclassified Bacteria	2|Bacteria	Q	Thi4 family	crtO	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158343_k127_1848968_37	484770.UFO1_0085	2.05e-145	475.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4H23F@909932|Negativicutes	1239|Firmicutes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB
SRR25158343_k127_1848968_116	682795.AciX8_3113	7.89e-55	200.0	COG4099@1|root,COG4099@2|Bacteria,3Y5YX@57723|Acidobacteria,2JMZ4@204432|Acidobacteriia	204432|Acidobacteriia	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158343_k127_1848968_0	402777.KB235903_gene788	0.0	2627.0	COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1GHDJ@1117|Cyanobacteria,1H8KY@1150|Oscillatoriales	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158343_k127_1848968_49	1173027.Mic7113_3984	1.139e-127	436.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HA21@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
SRR25158343_k127_1848968_21	383372.Rcas_2645	7.25e-184	588.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158343_k127_1848968_6	240015.ACP_2983	3.024e-321	1008.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158343_k127_1848968_87	933262.AXAM01000062_gene954	7.898e-75	261.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MHX7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SRR25158343_k127_1848968_105	335543.Sfum_3369	3.1e-62	237.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MQUA@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DSHCT	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SRR25158343_k127_1848968_100	498761.HM1_1931	4.013e-71	249.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158343_k127_1848968_188	1267535.KB906767_gene5149	5.822e-12	76.0	COG1652@1|root,COG1652@2|Bacteria,3Y84E@57723|Acidobacteria	57723|Acidobacteria	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158343_k127_1848968_26	204669.Acid345_2380	1.599e-167	538.0	COG0477@1|root,COG0477@2|Bacteria,3Y334@57723|Acidobacteria,2JIV9@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158343_k127_1848968_141	1191523.MROS_1096	7.221e-42	171.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
SRR25158343_k127_1848968_136	1267534.KB906754_gene3619	4.629e-46	173.0	COG2197@1|root,COG2197@2|Bacteria,3Y4DR@57723|Acidobacteria,2JJ2N@204432|Acidobacteriia	204432|Acidobacteriia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_1848968_59	313606.M23134_03791	4.8e-109	361.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,47NU5@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
SRR25158343_k127_1848968_75	1407650.BAUB01000003_gene753	2.604e-90	302.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1GYC7@1129|Synechococcus	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158343_k127_1848968_65	485913.Krac_12069	9.234e-100	334.0	COG0604@1|root,COG0604@2|Bacteria,2G7Z0@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158343_k127_1848968_89	1385513.N780_03990	2.737e-74	263.0	COG3320@1|root,COG3320@2|Bacteria,1TQPW@1239|Firmicutes,4HAFC@91061|Bacilli,2Y9AX@289201|Pontibacillus	91061|Bacilli	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SRR25158343_k127_1848968_202	204669.Acid345_3561	9.124e-07	61.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_1848968_170	1006004.GBAG_3626	1.228e-21	102.0	2FIAR@1|root,2ZVC2@2|Bacteria,1NKIH@1224|Proteobacteria,1ST91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Lysine-specific metallo-endopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aspzincin_M35
SRR25158343_k127_1848968_184	1183438.GKIL_3544	2.215e-15	82.0	COG1716@1|root,COG1716@2|Bacteria,1G9NG@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
SRR25158343_k127_1848968_145	1121396.KB892979_gene1668	6.124e-41	157.0	COG1716@1|root,COG1716@2|Bacteria,1N47K@1224|Proteobacteria,431RX@68525|delta/epsilon subdivisions,2WWF6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
SRR25158343_k127_1848968_19	404380.Gbem_3035	1.753e-192	623.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
SRR25158343_k127_1848968_27	1265505.ATUG01000001_gene4608	2.411e-166	550.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,2MK30@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
SRR25158343_k127_1848968_5	1408418.JNJH01000025_gene61	0.0	1024.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2TRT7@28211|Alphaproteobacteria,2JV12@204441|Rhodospirillales	204441|Rhodospirillales	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
SRR25158343_k127_1848968_74	330214.NIDE1984	5.29e-93	316.0	COG3520@1|root,COG3520@2|Bacteria,3J18D@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:T6SS_VasB	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
SRR25158343_k127_1848968_18	886293.Sinac_2407	1.598e-193	622.0	COG3519@1|root,COG3519@2|Bacteria,2IYES@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, VC_A0110 family	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
SRR25158343_k127_1848968_152	886293.Sinac_2408	1.629e-36	143.0	COG3518@1|root,COG3518@2|Bacteria,2J0UC@203682|Planctomycetes	203682|Planctomycetes	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
SRR25158343_k127_1848968_120	886293.Sinac_7146	2.431e-52	190.0	COG3157@1|root,COG3157@2|Bacteria,2J0G0@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion system effector, Hcp1 family	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SRR25158343_k127_1848968_10	886293.Sinac_2410	1.637e-238	745.0	COG3517@1|root,COG3517@2|Bacteria,2IXI1@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, EvpB VC_A0108 family	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
SRR25158343_k127_1848968_102	160488.PP_3100	4.655e-65	226.0	COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,1T190@1236|Gammaproteobacteria,1YVMB@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	impB	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
SRR25158343_k127_1848968_106	330214.NIDE1976	1.55e-61	227.0	COG3515@1|root,COG3515@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	impA	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N,T6SS_VasJ
SRR25158343_k127_1848968_99	330214.NIDE1975	3.854e-71	249.0	COG4455@1|root,COG4455@2|Bacteria	2|Bacteria	U	Protein of avirulence locus involved in temperature-dependent protein secretion	impE	-	-	ko:K03217,ko:K11898	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	ImpE,TPR_19
SRR25158343_k127_1848968_78	330214.NIDE1973	2.793e-88	329.0	COG3523@1|root,COG3523@2|Bacteria,3J159@40117|Nitrospirae	40117|Nitrospirae	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
SRR25158343_k127_1848968_163	1265502.KB905930_gene1403	4.954e-28	122.0	COG3455@1|root,COG3455@2|Bacteria,1NMWP@1224|Proteobacteria,2VH4H@28216|Betaproteobacteria,4AJ3Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	Type VI secretion system protein DotU	dotU1	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
SRR25158343_k127_1848968_62	1267535.KB906767_gene921	1.035e-107	364.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZF@57723|Acidobacteria,2JKHI@204432|Acidobacteriia	204432|Acidobacteriia	S	type VI secretion protein, VC_A0114 family	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
SRR25158343_k127_1848968_113	886293.Sinac_7297	5.408e-57	208.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158343_k127_1848968_197	1173029.JH980292_gene281	4.615e-08	65.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1G1FY@1117|Cyanobacteria,1H9AW@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
SRR25158343_k127_1848968_189	123214.PERMA_1513	6.71e-12	78.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2G442@200783|Aquificae	200783|Aquificae	M	Lytic transglycosylase catalytic	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158343_k127_1848968_200	29306.JOBE01000048_gene5575	3.73e-07	63.0	COG1716@1|root,COG1716@2|Bacteria,2GK5I@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158343_k127_1848968_190	1313172.YM304_02170	4.609e-11	76.0	COG1716@1|root,COG1716@2|Bacteria,2HG8X@201174|Actinobacteria,4CN6T@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158343_k127_1848968_28	945713.IALB_2142	1.301e-160	517.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158343_k127_1848968_155	509191.AEDB02000074_gene1799	1.962e-34	143.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158343_k127_1848968_192	429009.Adeg_1610	5.604e-10	68.0	COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,25BKT@186801|Clostridia	186801|Clostridia	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_1848968_164	661478.OP10G_1418	1.297e-25	122.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin,Thioredoxin,Thioredoxin_8
SRR25158343_k127_1848968_97	1278073.MYSTI_03719	1.595e-72	258.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158343_k127_1848968_212	316274.Haur_0353	0.0003447	52.0	COG2314@1|root,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
SRR25158343_k127_1848968_39	264732.Moth_0993	1.96e-138	447.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,42EVK@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM isocitrate isopropylmalate dehydrogenase	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158343_k127_1848968_151	483219.LILAB_00830	1.547e-36	142.0	2CNQU@1|root,32SHJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158343_k127_1848968_47	1117319.PSPO_10709	2.314e-129	428.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,2Q0T7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	COG0006 Xaa-Pro aminopeptidase	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158343_k127_1848968_104	1123508.JH636440_gene2559	1.523e-64	233.0	2EZN7@1|root,33ST8@2|Bacteria,2J2CB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_140	1078085.HMPREF1210_02279	1.231e-42	161.0	2CE8C@1|root,32RZC@2|Bacteria,1W0I1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_171	1123508.JH636440_gene2560	1.285e-21	99.0	2BYEG@1|root,349F2@2|Bacteria,2J42U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_175	596151.DesfrDRAFT_1004	9.749e-21	98.0	COG0515@1|root,COG0515@2|Bacteria,1R14V@1224|Proteobacteria,43D6A@68525|delta/epsilon subdivisions,2X8D1@28221|Deltaproteobacteria,2MDPG@213115|Desulfovibrionales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_50	1395571.TMS3_0115850	7.629e-127	411.0	COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,1RQ5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_1848968_187	1463917.JODC01000007_gene7664	4.064e-12	72.0	2E9YS@1|root,3344A@2|Bacteria,2IJZ5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR25158343_k127_1848968_80	1382359.JIAL01000001_gene2075	2.593e-87	306.0	COG2234@1|root,COG2234@2|Bacteria,3Y53E@57723|Acidobacteria,2JKAS@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158343_k127_1848968_92	1286632.P278_02920	2.835e-73	255.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,1I1XD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158343_k127_1848968_16	1340493.JNIF01000003_gene3519	4.368e-202	665.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1848968_158	1173027.Mic7113_2654	3.878e-32	130.0	COG1670@1|root,COG1670@2|Bacteria,1G6F2@1117|Cyanobacteria	1117|Cyanobacteria	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158343_k127_1848968_138	1123073.KB899243_gene666	2.182e-44	164.0	2CX7C@1|root,32T1D@2|Bacteria,1N2N3@1224|Proteobacteria,1S4YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_101	234267.Acid_2365	1.697e-70	261.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158343_k127_1848968_159	570952.ATVH01000019_gene827	6.543e-32	131.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,2JU0D@204441|Rhodospirillales	204441|Rhodospirillales	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158343_k127_1848968_2	234267.Acid_2365	0.0	1242.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158343_k127_1848968_109	1254432.SCE1572_10340	4.465e-58	219.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WK41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR25158343_k127_1848968_142	671143.DAMO_1259	7.821e-42	161.0	COG1309@1|root,COG1309@2|Bacteria,2NQ8G@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	MA20_16815	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158343_k127_1848968_213	1549858.MC45_06205	0.0004809	47.0	2EJM3@1|root,33DC0@2|Bacteria,1NFBE@1224|Proteobacteria,2UH3B@28211|Alphaproteobacteria,2KE6K@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_210	1121952.ATXT01000013_gene2425	0.000224	48.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4FQDW@85023|Microbacteriaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158343_k127_1848968_44	1173023.KE650771_gene251	1.907e-132	439.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1JHEY@1189|Stigonemataceae	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158343_k127_1848968_166	215803.DB30_5360	6.89e-24	111.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_208	1267534.KB906757_gene1000	0.0001112	53.0	COG1629@1|root,COG4771@2|Bacteria,3Y3Y0@57723|Acidobacteria,2JIYU@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_1848968_68	927677.ALVU02000001_gene1455	6.447e-98	325.0	COG1125@1|root,COG1125@2|Bacteria	2|Bacteria	E	glycine betaine transport	yehX	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iECED1_1282.ECED1_2573,iEcE24377_1341.EcE24377A_2418,iPC815.YPO1198	ABC_tran,CBS
SRR25158343_k127_1848968_196	929704.Myrod_2820	8.349e-09	65.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,47GZM@76831|Myroides	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
SRR25158343_k127_1848968_112	234267.Acid_0913	5.167e-57	206.0	COG0321@1|root,COG0321@2|Bacteria,3Y448@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
SRR25158343_k127_1848968_129	1173022.Cri9333_2083	2.409e-48	186.0	COG0508@1|root,COG0508@2|Bacteria,1G0YZ@1117|Cyanobacteria,1H75Z@1150|Oscillatoriales	1117|Cyanobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_35	1183438.GKIL_3395	6.052e-148	501.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_1848968_128	234267.Acid_1209	1.839e-49	183.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_1848968_204	439235.Dalk_5269	2.572e-06	58.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R09K@1224|Proteobacteria	1224|Proteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2
SRR25158343_k127_1848968_43	1183438.GKIL_3395	1.057e-132	454.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_1848968_135	1183438.GKIL_3942	3.165e-46	173.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158343_k127_1848968_86	945713.IALB_2676	4.803e-75	259.0	COG4947@1|root,COG4947@2|Bacteria	2|Bacteria	P	esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158343_k127_1848968_40	401053.AciPR4_0705	1.233e-136	466.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158343_k127_1848968_96	278963.ATWD01000001_gene2127	1.002e-72	258.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158343_k127_1848968_57	909663.KI867150_gene2102	4.698e-110	379.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MQ74@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
SRR25158343_k127_1848968_209	1499967.BAYZ01000147_gene720	0.0001227	51.0	COG2891@1|root,COG2891@2|Bacteria,2NRRJ@2323|unclassified Bacteria	2|Bacteria	M	rod shape-determining protein MreD	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158343_k127_1848968_148	1449126.JQKL01000013_gene3435	1.158e-39	159.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,268FA@186813|unclassified Clostridiales	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158343_k127_1848968_22	1382359.JIAL01000001_gene760	2.53e-172	545.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158343_k127_1848968_8	472759.Nhal_1379	1.11e-268	850.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1S0BH@1236|Gammaproteobacteria,1X076@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158343_k127_1848968_173	472759.Nhal_1380	4.889e-21	97.0	COG0071@1|root,COG0071@2|Bacteria,1NPJI@1224|Proteobacteria,1SRY5@1236|Gammaproteobacteria,1X21C@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158343_k127_1848968_160	323848.Nmul_A1198	2.167e-29	122.0	COG0517@1|root,COG0517@2|Bacteria,1QTWY@1224|Proteobacteria,2VTYW@28216|Betaproteobacteria,373PN@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158343_k127_1848968_179	1379698.RBG1_1C00001G0683	4.237e-19	91.0	COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria	2|Bacteria	P	(Rieske (2Fe-2S) domain)	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158343_k127_1848968_64	204669.Acid345_2070	2.654e-104	347.0	2C1VH@1|root,2Z7Z3@2|Bacteria,3Y4CU@57723|Acidobacteria,2JJ58@204432|Acidobacteriia	204432|Acidobacteriia	S	3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Kdo_hydroxy
SRR25158343_k127_1848968_162	240016.ABIZ01000001_gene1444	3.161e-28	119.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,2IURJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158343_k127_1848968_67	215803.DB30_3960	3.692e-98	329.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42NV3@68525|delta/epsilon subdivisions,2X36K@28221|Deltaproteobacteria,2YWC6@29|Myxococcales	28221|Deltaproteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158343_k127_1848968_42	639030.JHVA01000001_gene1243	3.917e-134	437.0	COG0379@1|root,COG0379@2|Bacteria,3Y328@57723|Acidobacteria,2JHY8@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158343_k127_1848968_7	1232410.KI421422_gene2032	4.398e-290	911.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158343_k127_1848968_114	748449.Halha_0004	2.497e-56	211.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WA8H@53433|Halanaerobiales	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158343_k127_1848968_154	1166018.FAES_5179	1.718e-34	133.0	2EJF2@1|root,32Z95@2|Bacteria,4P5WW@976|Bacteroidetes,47VU2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_149	937777.Deipe_2227	4.531e-39	150.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	1.1.1.42,1.3.1.85	ko:K00031,ko:K14446	ko00020,ko00480,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00373,M00740	R00267,R00268,R01899,R09291	RC00001,RC00084,RC00114,RC00626,RC02481,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,GGDEF,PAS_9
SRR25158343_k127_1848968_20	313624.NSP_38100	4.522e-186	590.0	COG2312@1|root,COG2312@2|Bacteria,1GK9Y@1117|Cyanobacteria,1HMEE@1161|Nostocales	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRR25158343_k127_1848968_167	1353276.JADR01000003_gene2798	9.912e-24	107.0	COG0526@1|root,COG0526@2|Bacteria,4NT1F@976|Bacteroidetes,1I473@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158343_k127_1848968_131	1123371.ATXH01000033_gene423	6.89e-48	178.0	COG1309@1|root,COG1309@2|Bacteria,2GHH2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158343_k127_1848968_30	1379270.AUXF01000004_gene3094	7.498e-153	503.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158343_k127_1848968_185	195253.Syn6312_0756	7.302e-15	86.0	COG1596@1|root,COG1596@2|Bacteria,1G0AJ@1117|Cyanobacteria,1GYX1@1129|Synechococcus	1117|Cyanobacteria	M	Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158343_k127_1848968_36	1408444.JHYC01000016_gene2059	4.598e-147	477.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1JCAU@118969|Legionellales	118969|Legionellales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158343_k127_1848968_61	448385.sce1419	1.231e-108	382.0	COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,43F3Q@68525|delta/epsilon subdivisions,2X3A4@28221|Deltaproteobacteria,2YV2U@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
SRR25158343_k127_1848968_156	1443665.JACA01000022_gene5173	6.383e-34	151.0	2EKV8@1|root,33EIT@2|Bacteria,4PAWN@976|Bacteroidetes,1IHKK@117743|Flavobacteriia,2YHTD@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_157	756067.MicvaDRAFT_4958	2.998e-33	134.0	2CKCH@1|root,331PP@2|Bacteria,1G6N7@1117|Cyanobacteria,1HC5R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_107	945713.IALB_2758	2.023e-60	215.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_1848968_84	1123248.KB893327_gene796	6.144e-77	293.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158343_k127_1848968_146	545264.KB898756_gene1615	6.98e-41	153.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158343_k127_1848968_199	517418.Ctha_2311	9.483e-08	63.0	COG0457@1|root,COG0457@2|Bacteria	517418.Ctha_2311|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_72	350688.Clos_1079	1.045e-94	336.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,36EVK@31979|Clostridiaceae	186801|Clostridia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_1848968_69	1089547.KB913013_gene3293	1.292e-96	323.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,47JNV@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
SRR25158343_k127_1848968_33	485913.Krac_8259	1.184e-149	488.0	COG1233@1|root,COG1233@2|Bacteria,2G68M@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amine oxidase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158343_k127_1848968_203	926566.Terro_3361	1.245e-06	60.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,DUF2637,TonB_C,YXWGXW
SRR25158343_k127_1848968_73	1070319.CAGGBEG34_190038	1.738e-93	328.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158343_k127_1848968_126	1340493.JNIF01000003_gene4236	3.742e-50	184.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158343_k127_1848968_76	744872.Spica_0684	4.812e-90	311.0	COG0265@1|root,COG0265@2|Bacteria,2J6JY@203691|Spirochaetes	203691|Spirochaetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_1848968_94	1128421.JAGA01000002_gene1139	4.235e-73	250.0	COG3663@1|root,COG3663@2|Bacteria,2NRDF@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	mug	GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.28,6.3.3.2	ko:K01934,ko:K03649	ko00670,ko01100,ko03410,map00670,map01100,map03410	-	R02301	RC00183	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158343_k127_1848968_9	1198114.AciX9_3738	5.107e-245	792.0	COG1629@1|root,COG4771@2|Bacteria,3Y42T@57723|Acidobacteria,2JIWF@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_1848968_15	1158345.JNLL01000001_gene818	8.549e-204	646.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G3NT@200783|Aquificae	200783|Aquificae	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158343_k127_1848968_191	682795.AciX8_4403	2.151e-10	73.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158343_k127_1848968_34	234267.Acid_5235	3.688e-148	483.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158343_k127_1848968_132	1267535.KB906767_gene2360	7.447e-48	174.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158343_k127_1848968_98	926550.CLDAP_16210	8.885e-72	248.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158343_k127_1848968_71	935836.JAEL01000111_gene684	1.747e-95	321.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158343_k127_1848968_176	575586.HMPREF0016_03044	1.23e-20	94.0	COG1724@1|root,COG1724@2|Bacteria,1R11S@1224|Proteobacteria,1T4TC@1236|Gammaproteobacteria,3NPHU@468|Moraxellaceae	1236|Gammaproteobacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_1848968_177	548476.cauri_2257	1.704e-20	96.0	COG4226@1|root,COG4226@2|Bacteria,2IRP5@201174|Actinobacteria,22NMI@1653|Corynebacteriaceae	201174|Actinobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
SRR25158343_k127_1848968_81	526227.Mesil_0639	1.632e-85	292.0	COG1079@1|root,COG1079@2|Bacteria,1WJJD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158343_k127_1848968_79	926692.AZYG01000094_gene2006	6.545e-88	302.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WAFN@53433|Halanaerobiales	186801|Clostridia	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158343_k127_1848968_144	240015.ACP_2406	1.075e-41	159.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158343_k127_1848968_4	1121405.dsmv_2717	0.0	1075.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158343_k127_1848968_161	633149.Bresu_2368	2.174e-29	130.0	COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,2U7GA@28211|Alphaproteobacteria,2KGBW@204458|Caulobacterales	204458|Caulobacterales	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,VanY
SRR25158343_k127_1848968_195	861299.J421_1420	3.079e-09	69.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	SLH,YkuD
SRR25158343_k127_1848968_174	717605.Theco_2404	6.029e-21	101.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158343_k127_1848968_139	1123250.KB908379_gene1123	8.593e-44	171.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4H2CB@909932|Negativicutes	909932|Negativicutes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158343_k127_1859874_0	1183438.GKIL_0464	7.944e-133	433.0	COG0677@1|root,COG0677@2|Bacteria,1G4FW@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158343_k127_1859917_0	1183438.GKIL_0464	9.816e-132	430.0	COG0677@1|root,COG0677@2|Bacteria,1G4FW@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158343_k127_193904_1	391612.CY0110_06409	1.494e-12	70.0	COG3668@1|root,COG3668@2|Bacteria,1G90A@1117|Cyanobacteria,3KKKY@43988|Cyanothece	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158343_k127_193904_0	228410.NE2536	1.461e-150	482.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,2VN7F@28216|Betaproteobacteria,374M0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	InterPro IPR001584 COGs COG1425	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve
SRR25158343_k127_2012683_88	1211114.ALIP01000022_gene2450	5.248e-13	69.0	COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,1RPDB@1236|Gammaproteobacteria,1X3J9@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158343_k127_2012683_34	762903.Pedsa_0506	6.993e-99	336.0	2DB8U@1|root,2Z7SW@2|Bacteria,4NEUK@976|Bacteroidetes,1IQMM@117747|Sphingobacteriia	976|Bacteroidetes	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
SRR25158343_k127_2012683_83	667015.Bacsa_3637	8.31e-19	90.0	COG1917@1|root,COG1917@2|Bacteria,4NSEB@976|Bacteroidetes,2FSS8@200643|Bacteroidia,4AQZA@815|Bacteroidaceae	976|Bacteroidetes	S	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_2012683_87	1229780.BN381_40059	1.019e-13	85.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158343_k127_2012683_0	234267.Acid_2734	0.0	1112.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158343_k127_2012683_31	861299.J421_0382	4.419e-109	366.0	COG1940@1|root,COG1940@2|Bacteria,1ZV0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158343_k127_2012683_25	382464.ABSI01000011_gene2734	1.478e-115	395.0	COG0038@1|root,COG0038@2|Bacteria,46U35@74201|Verrucomicrobia,2IU1K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Voltage_CLC
SRR25158343_k127_2012683_85	204669.Acid345_3772	9.577e-16	84.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158343_k127_2012683_48	861299.J421_3197	8.693e-73	256.0	COG0796@1|root,COG0796@2|Bacteria,1ZUQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158343_k127_2012683_43	868595.Desca_0609	8.626e-86	290.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,26123@186807|Peptococcaceae	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
SRR25158343_k127_2012683_80	329726.AM1_4023	3.891e-20	97.0	COG4719@1|root,COG4719@2|Bacteria,1G6YW@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158343_k127_2012683_63	1229172.JQFA01000002_gene3172	1.987e-42	177.0	COG4964@1|root,COG4964@2|Bacteria,1G3U8@1117|Cyanobacteria,1H8H0@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the GSP D family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_35	1121104.AQXH01000001_gene1308	1.092e-98	367.0	COG2885@1|root,COG3188@1|root,COG2885@2|Bacteria,COG3188@2|Bacteria	2|Bacteria	NU	fimbrial usher porin activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF11,OmpA,Plug,SdrD_B,TonB_dep_Rec
SRR25158343_k127_2012683_51	713586.KB900536_gene2793	7.07e-60	224.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,1T2IX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_7	1267535.KB906767_gene2436	2.503e-204	647.0	COG0578@1|root,COG0578@2|Bacteria,3Y2YF@57723|Acidobacteria,2JI40@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158343_k127_2012683_39	1123276.KB893271_gene4004	1.917e-92	309.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158343_k127_2012683_29	622637.KE124769_gene221	2.394e-110	368.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,2U2RP@28211|Alphaproteobacteria,36ZV4@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158343_k127_2012683_89	1123276.KB893271_gene4004	2.067e-11	66.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158343_k127_2012683_11	218284.CCDN010000001_gene1818	3.161e-188	595.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,4HBRG@91061|Bacilli,1ZD6D@1386|Bacillus	91061|Bacilli	CF	dihydroorotate dehydrogenase	preA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
SRR25158343_k127_2012683_32	864702.OsccyDRAFT_2625	9.532e-107	355.0	COG0454@1|root,COG0456@2|Bacteria,1G2QV@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158343_k127_2012683_82	1223410.KN050846_gene73	7.688e-20	93.0	2EKX6@1|root,33EKQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_36	1122621.ATZA01000001_gene1942	8.199e-96	323.0	COG2234@1|root,COG2234@2|Bacteria,4NMZ4@976|Bacteroidetes,1IRUC@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158343_k127_2012683_84	1408287.AXUR01000021_gene419	1.438e-16	86.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158343_k127_2012683_21	1499680.CCFE01000011_gene714	6.985e-120	394.0	COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,1ZS5F@1386|Bacillus	91061|Bacilli	I	Alpha/beta hydrolase family	pepI	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158343_k127_2012683_27	1356854.N007_08015	1.714e-113	381.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli	91061|Bacilli	E	glutamate synthase	gltD	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
SRR25158343_k127_2012683_60	927677.ALVU02000001_gene1596	5.179e-46	169.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158343_k127_2012683_71	700598.Niako_1792	8.402e-35	143.0	2DM1Z@1|root,31DJ0@2|Bacteria,4NRU0@976|Bacteroidetes,1IYWW@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_86	192952.MM_2984	7.75e-14	76.0	arCOG07867@1|root,arCOG07867@2157|Archaea,2Y4V4@28890|Euryarchaeota,2NB6Q@224756|Methanomicrobia	224756|Methanomicrobia	S	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158343_k127_2012683_16	1396141.BATP01000059_gene2564	1.85e-146	468.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158343_k127_2012683_54	204669.Acid345_2503	4.481e-56	209.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	VPA0557	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
SRR25158343_k127_2012683_73	1267534.KB906760_gene1507	2.824e-31	137.0	COG0457@1|root,COG0457@2|Bacteria,3Y7NG@57723|Acidobacteria,2JMP3@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158343_k127_2012683_5	714943.Mucpa_6392	5.126e-240	749.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IP6V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140,ko:K22187	ko00040,ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00040,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935,R11768	RC00004,RC00080,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158343_k127_2012683_42	864051.BurJ1DRAFT_0894	6.97e-90	320.0	COG0823@1|root,COG0823@2|Bacteria,1R7MY@1224|Proteobacteria	1224|Proteobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PD40
SRR25158343_k127_2012683_46	684949.ATTJ01000001_gene496	6.602e-78	280.0	2F7K7@1|root,3400T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_12	1121342.AUCO01000017_gene2851	1.637e-179	574.0	COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,247WK@186801|Clostridia,36VS3@31979|Clostridiaceae	186801|Clostridia	FH	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	pucI	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158343_k127_2012683_19	204669.Acid345_1052	5.433e-122	435.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_2012683_75	864702.OsccyDRAFT_2580	2.541e-28	118.0	COG3409@1|root,COG3409@2|Bacteria,1GR82@1117|Cyanobacteria,1HIA0@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_91	1198114.AciX9_2169	4.038e-10	68.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_2012683_90	1267535.KB906767_gene1959	3.321e-10	64.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_2012683_57	1037409.BJ6T_87330	5.354e-50	189.0	COG0596@1|root,COG0596@2|Bacteria,1R9VJ@1224|Proteobacteria,2U26I@28211|Alphaproteobacteria,3JQRZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158343_k127_2012683_26	204669.Acid345_4396	4.278e-115	404.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_2012683_52	234267.Acid_1209	1.513e-59	212.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_2012683_9	215803.DB30_5624	1.449e-196	622.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42PXH@68525|delta/epsilon subdivisions,2WKEX@28221|Deltaproteobacteria,2YTWX@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158343_k127_2012683_30	204669.Acid345_1475	2.992e-110	368.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158343_k127_2012683_14	204669.Acid345_1474	5.578e-168	539.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158343_k127_2012683_15	760192.Halhy_3357	2.197e-158	511.0	COG0160@1|root,COG0160@2|Bacteria,4NIHH@976|Bacteroidetes,1IWIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158343_k127_2012683_99	1384066.JAGT01000001_gene608	0.0006003	48.0	COG0454@1|root,COG0456@2|Bacteria,1V6P2@1239|Firmicutes,24NU3@186801|Clostridia,3WKWF@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158343_k127_2012683_6	472759.Nhal_1374	3.146e-205	654.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158343_k127_2012683_77	926566.Terro_0195	7.437e-28	126.0	COG0308@1|root,COG0308@2|Bacteria,3Y6V6@57723|Acidobacteria,2JMGB@204432|Acidobacteriia	204432|Acidobacteriia	E	ERAP1-like C-terminal domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158343_k127_2012683_8	1198114.AciX9_0699	1.77e-200	657.0	COG0308@1|root,COG0308@2|Bacteria,3Y6V6@57723|Acidobacteria,2JMGB@204432|Acidobacteriia	204432|Acidobacteriia	E	ERAP1-like C-terminal domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158343_k127_2012683_55	1313421.JHBV01000023_gene5159	8.45e-54	199.0	COG1183@1|root,COG1183@2|Bacteria	2|Bacteria	I	phosphatidylcholine synthase activity	pcs	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576	2.7.8.24,2.7.8.8	ko:K01004,ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800,R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158343_k127_2012683_18	91464.S7335_5262	2.948e-127	423.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1GZYT@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158343_k127_2012683_70	237368.SCABRO_03987	5.541e-36	145.0	COG3222@1|root,COG3222@2|Bacteria,2J0B9@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SRR25158343_k127_2012683_44	316067.Geob_2204	6.224e-85	290.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,42NDF@68525|delta/epsilon subdivisions,2WJPS@28221|Deltaproteobacteria,43TE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158343_k127_2012683_24	945713.IALB_1972	3.063e-116	382.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
SRR25158343_k127_2012683_68	330214.NIDE0159	3.065e-37	142.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	yurZ	-	2.3.1.12,4.1.1.44	ko:K00627,ko:K01607	ko00010,ko00020,ko00362,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00020,map00362,map00620,map01100,map01110,map01120,map01130,map01200,map01220	M00307	R00209,R02569,R03470	RC00004,RC00938,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CMD
SRR25158343_k127_2012683_65	1379698.RBG1_1C00001G0694	2.671e-39	152.0	2AXD3@1|root,31PCE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SRR25158343_k127_2012683_76	1340493.JNIF01000003_gene4373	2.796e-28	120.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158343_k127_2012683_3	373994.Riv7116_6872	7.344e-249	775.0	COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria,1HIBK@1161|Nostocales	1117|Cyanobacteria	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158343_k127_2012683_97	1122135.KB893138_gene1094	2.766e-05	53.0	2DTQU@1|root,33MB4@2|Bacteria,1NPT6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_72	1499967.BAYZ01000194_gene3125	1.801e-34	135.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158343_k127_2012683_37	468059.AUHA01000005_gene2523	1.898e-95	319.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IP44@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158343_k127_2012683_49	234267.Acid_6750	3.876e-63	222.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158343_k127_2012683_10	991.IW20_16610	2.251e-196	626.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia,2NTIB@237|Flavobacterium	976|Bacteroidetes	P	Sulfate permease family	sulP	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Sulfate_transp
SRR25158343_k127_2012683_38	1121896.JMLU01000034_gene630	2.341e-94	314.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,2NVS1@237|Flavobacterium	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158343_k127_2012683_33	1122225.AULQ01000010_gene251	3.363e-102	338.0	COG3541@1|root,COG3541@2|Bacteria,4NI5D@976|Bacteroidetes,1HYX8@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
SRR25158343_k127_2012683_23	945713.IALB_2894	1.129e-118	385.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
SRR25158343_k127_2012683_41	945713.IALB_2895	1.486e-90	315.0	COG0719@1|root,COG0719@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
SRR25158343_k127_2012683_66	203119.Cthe_2572	5.685e-38	150.0	2BYHH@1|root,32X60@2|Bacteria,1VVGV@1239|Firmicutes,25124@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_13	234267.Acid_7702	1.725e-173	552.0	COG0520@1|root,COG0520@2|Bacteria,3Y2SC@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158343_k127_2012683_74	913865.DOT_1151	2.231e-30	124.0	2E4TA@1|root,32ZMP@2|Bacteria,1W3FK@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_2	204669.Acid345_0753	6.125e-263	817.0	COG3534@1|root,COG3534@2|Bacteria,3Y2ZG@57723|Acidobacteria,2JKB9@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SRR25158343_k127_2012683_28	760192.Halhy_0172	2.717e-111	366.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,1IPUH@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158343_k127_2012683_20	1254432.SCE1572_35695	4.892e-120	395.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,4306C@68525|delta/epsilon subdivisions,2WVFZ@28221|Deltaproteobacteria,2YU0U@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein domain	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158343_k127_2012683_95	1382359.JIAL01000001_gene2644	1.068e-06	59.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158343_k127_2012683_64	1121007.AUML01000003_gene2554	4.846e-42	156.0	COG3232@1|root,COG3232@2|Bacteria,4NQRH@976|Bacteroidetes,1I396@117743|Flavobacteriia,2YJUU@290174|Aquimarina	976|Bacteroidetes	E	5-carboxymethyl-2-hydroxymuconate isomerase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158343_k127_2012683_47	1121286.AUMT01000015_gene3712	2.256e-73	251.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,1I2VH@117743|Flavobacteriia,3ZNRA@59732|Chryseobacterium	976|Bacteroidetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158343_k127_2012683_53	362418.IW19_12130	1.161e-57	204.0	COG3708@1|root,COG3708@2|Bacteria,4NQ46@976|Bacteroidetes,1I45F@117743|Flavobacteriia,2NW6B@237|Flavobacterium	976|Bacteroidetes	K	transcription activator, effector binding	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
SRR25158343_k127_2012683_59	378806.STAUR_0109	6.688e-47	171.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,42U1Z@68525|delta/epsilon subdivisions,2WQ05@28221|Deltaproteobacteria,2Z1RY@29|Myxococcales	28221|Deltaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_2012683_4	405948.SACE_5619	2.07e-240	755.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158343_k127_2012683_79	886293.Sinac_1166	1.39e-24	114.0	2E2WE@1|root,32XXR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_56	754476.Q7A_1538	1.71e-52	188.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,461GC@72273|Thiotrichales	72273|Thiotrichales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158343_k127_2012683_78	980584.AFPB01000138_gene2668	1.133e-25	111.0	COG2346@1|root,COG2346@2|Bacteria,4PK6E@976|Bacteroidetes,1I8Z5@117743|Flavobacteriia,406MH@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	-
SRR25158343_k127_2012683_50	491205.JARQ01000006_gene2674	3.094e-62	232.0	COG2304@1|root,COG2304@2|Bacteria,4NIM2@976|Bacteroidetes	976|Bacteroidetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SRR25158343_k127_2012683_17	1267535.KB906767_gene873	8.778e-140	452.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	204432|Acidobacteriia	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158343_k127_2012683_62	1122197.ATWI01000015_gene843	1.471e-44	169.0	2EGH2@1|root,33A95@2|Bacteria,1N4Z1@1224|Proteobacteria,1SB1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4375
SRR25158343_k127_2012683_1	443143.GM18_0728	1.36e-284	882.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158343_k127_2012683_69	1198114.AciX9_2795	6.021e-37	154.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_2012683_61	240292.Ava_3740	5.477e-45	168.0	COG3467@1|root,COG3467@2|Bacteria,1G64G@1117|Cyanobacteria,1HS7G@1161|Nostocales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158343_k127_2012683_58	861299.J421_1010	6.504e-50	184.0	COG3127@1|root,COG3127@2|Bacteria,1ZU3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2012683_67	1267535.KB906767_gene2392	6.684e-38	145.0	COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRR25158343_k127_2012683_22	867903.ThesuDRAFT_01903	6.495e-119	393.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia	186801|Clostridia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
SRR25158343_k127_2012683_40	292459.STH2612	1.742e-91	322.0	COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,24DV3@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
SRR25158343_k127_2012683_45	1045004.OKIT_1444	6.418e-80	276.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,4AWH0@81850|Leuconostocaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158343_k127_2012683_81	639030.JHVA01000001_gene1556	4.278e-20	89.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_2018762_107	1211114.ALIP01000022_gene2450	1.807e-12	68.0	COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,1RPDB@1236|Gammaproteobacteria,1X3J9@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158343_k127_2018762_62	1112214.AHIS01000046_gene2222	2.54e-95	318.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,2K0AT@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158343_k127_2018762_51	1267534.KB906756_gene262	9.01e-117	385.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria,2JI9I@204432|Acidobacteriia	204432|Acidobacteriia	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158343_k127_2018762_53	1001240.GY21_18050	2.461e-114	387.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria,4FMYG@85023|Microbacteriaceae	201174|Actinobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
SRR25158343_k127_2018762_57	926556.Echvi_4034	5.929e-106	351.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	-	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158343_k127_2018762_54	1382359.JIAL01000001_gene1348	8.65e-113	368.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria,2JHIF@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_2018762_77	1128421.JAGA01000002_gene1756	9.567e-68	244.0	COG0006@1|root,COG0006@2|Bacteria,2NQIR@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	Creatinase_N,Peptidase_M24
SRR25158343_k127_2018762_27	1519464.HY22_10660	1.02e-185	591.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
SRR25158343_k127_2018762_71	1198114.AciX9_1762	5.561e-73	252.0	COG0800@1|root,COG0800@2|Bacteria,3Y4HZ@57723|Acidobacteria,2JKJ9@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158343_k127_2018762_15	1408473.JHXO01000013_gene495	1.499e-243	763.0	COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,2FNGR@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynBA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRR25158343_k127_2018762_79	639030.JHVA01000001_gene3967	5.958e-65	230.0	COG2186@1|root,COG2186@2|Bacteria,3Y47U@57723|Acidobacteria,2JI8P@204432|Acidobacteriia	204432|Acidobacteriia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158343_k127_2018762_104	682795.AciX8_2341	4.909e-14	79.0	COG0662@1|root,COG0662@2|Bacteria,3Y84R@57723|Acidobacteria,2JN54@204432|Acidobacteriia	204432|Acidobacteriia	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_12	926549.KI421517_gene2787	8.032e-253	794.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,47MS0@768503|Cytophagia	976|Bacteroidetes	V	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
SRR25158343_k127_2018762_75	762903.Pedsa_3357	4.339e-70	246.0	COG2755@1|root,COG2755@2|Bacteria,4NKE5@976|Bacteroidetes,1IQQE@117747|Sphingobacteriia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	rhgT_1	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Polysacc_deac_1
SRR25158343_k127_2018762_32	518766.Rmar_2391	2.34e-167	539.0	COG5434@1|root,COG5434@2|Bacteria,4NEM8@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Glyco_hydro_88,Pectate_lyase_3
SRR25158343_k127_2018762_60	1121929.KB898669_gene3217	4.461e-99	349.0	COG1657@1|root,COG4223@1|root,COG4412@1|root,COG4677@1|root,COG4733@1|root,COG5297@1|root,COG1657@2|Bacteria,COG4223@2|Bacteria,COG4412@2|Bacteria,COG4677@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria,1UWTS@1239|Firmicutes,4I2GN@91061|Bacilli,471DJ@74385|Gracilibacillus	91061|Bacilli	GI	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
SRR25158343_k127_2018762_25	234267.Acid_7510	2.354e-191	642.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_2018762_73	1123269.NX02_21130	1.332e-71	250.0	2DN0U@1|root,32UTB@2|Bacteria,1MZ2J@1224|Proteobacteria,2UHAI@28211|Alphaproteobacteria,2K24S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_90	1121104.AQXH01000002_gene535	9.774e-37	157.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IRFW@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158343_k127_2018762_93	864702.OsccyDRAFT_3546	3.493e-29	122.0	2EP9T@1|root,33GWJ@2|Bacteria,1GF45@1117|Cyanobacteria,1HGH2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_72	926550.CLDAP_15280	1.231e-71	267.0	COG0793@1|root,COG3468@1|root,COG0793@2|Bacteria,COG3468@2|Bacteria,2G7PQ@200795|Chloroflexi	200795|Chloroflexi	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158343_k127_2018762_86	1123269.NX02_21130	4.183e-47	179.0	2DN0U@1|root,32UTB@2|Bacteria,1MZ2J@1224|Proteobacteria,2UHAI@28211|Alphaproteobacteria,2K24S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_113	1118235.CAJH01000013_gene755	1.849e-06	57.0	2E3TX@1|root,32YRB@2|Bacteria,1NAJY@1224|Proteobacteria,1SDPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_102	273677.BW34_00441	2.491e-18	90.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4FNGB@85023|Microbacteriaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_2018762_83	639030.JHVA01000001_gene971	5.039e-53	195.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158343_k127_2018762_39	1121930.AQXG01000005_gene709	4.309e-146	500.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158343_k127_2018762_65	1267534.KB906757_gene1079	2.616e-80	279.0	COG1609@1|root,COG1609@2|Bacteria,3Y49N@57723|Acidobacteria,2JKAT@204432|Acidobacteriia	204432|Acidobacteriia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158343_k127_2018762_23	1121904.ARBP01000031_gene559	1.113e-196	625.0	COG2755@1|root,COG2755@2|Bacteria,4NK31@976|Bacteroidetes	976|Bacteroidetes	E	Sialate O-acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
SRR25158343_k127_2018762_13	1408813.AYMG01000006_gene4250	1.833e-250	796.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1IW9U@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_78	1340493.JNIF01000004_gene223	1.374e-65	225.0	COG1917@1|root,COG1917@2|Bacteria,3Y4HX@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_2018762_17	272134.KB731326_gene163	1.541e-237	745.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria,1H96B@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158343_k127_2018762_35	1121957.ATVL01000008_gene4016	4.956e-151	483.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47JBA@768503|Cytophagia	976|Bacteroidetes	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_2018762_64	1121895.Q765_09835	7.945e-81	274.0	COG0716@1|root,COG0716@2|Bacteria,4NNTA@976|Bacteroidetes,1I18K@117743|Flavobacteriia,2NTPK@237|Flavobacterium	976|Bacteroidetes	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
SRR25158343_k127_2018762_30	1322246.BN4_11133	9.366e-179	567.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2MA3T@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_2018762_40	1123276.KB893269_gene4783	7.122e-146	466.0	COG0656@1|root,COG0656@2|Bacteria,4NFTA@976|Bacteroidetes,47JTN@768503|Cytophagia	976|Bacteroidetes	S	PFAM Aldo keto reductase family	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_2018762_47	221288.JH992901_gene5205	1.633e-131	425.0	COG2207@1|root,COG2207@2|Bacteria,1G4F4@1117|Cyanobacteria,1JMEF@1189|Stigonemataceae	1117|Cyanobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
SRR25158343_k127_2018762_92	305900.GV64_23715	1.962e-34	143.0	29765@1|root,2ZUE2@2|Bacteria,1NEEK@1224|Proteobacteria,1SM02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1961
SRR25158343_k127_2018762_26	1303518.CCALI_02567	2.833e-186	603.0	28KZU@1|root,2ZAF0@2|Bacteria	2|Bacteria	G	Rhamnogalacturonate lyase	-	GO:0005575,GO:0005576	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,Rhamnogal_lyase,fn3_3
SRR25158343_k127_2018762_41	1173026.Glo7428_4012	1.552e-141	462.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
SRR25158343_k127_2018762_21	682795.AciX8_2295	8.287e-202	648.0	28KZU@1|root,2ZAF0@2|Bacteria	2|Bacteria	G	Rhamnogalacturonate lyase	-	GO:0005575,GO:0005576	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,Rhamnogal_lyase,fn3_3
SRR25158343_k127_2018762_31	742766.HMPREF9455_02338	1.542e-176	572.0	COG5434@1|root,COG5434@2|Bacteria,4NI6V@976|Bacteroidetes,2G2P0@200643|Bacteroidia,231Y2@171551|Porphyromonadaceae	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
SRR25158343_k127_2018762_29	861299.J421_5619	2.69e-180	576.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	3.2.1.15	ko:K01184	ko00040,ko01100,map00040,map01100	M00081	R01982,R02360	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_28,Pectate_lyase_3
SRR25158343_k127_2018762_63	234267.Acid_1173	1.826e-94	318.0	COG0657@1|root,COG0657@2|Bacteria,3Y2TC@57723|Acidobacteria	57723|Acidobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158343_k127_2018762_6	278963.ATWD01000001_gene1323	6.958e-285	893.0	COG3250@1|root,COG3250@2|Bacteria,3Y6CM@57723|Acidobacteria,2JKZF@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_109	1382359.JIAL01000001_gene1410	2.972e-08	57.0	COG3250@1|root,COG3250@2|Bacteria,3Y6CM@57723|Acidobacteria,2JKZF@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_70	1502852.FG94_02233	2.771e-74	260.0	COG2755@1|root,COG2755@2|Bacteria,1NRMA@1224|Proteobacteria	1224|Proteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_2018762_45	234267.Acid_4055	1.313e-132	434.0	COG0823@1|root,COG0823@2|Bacteria,3Y2NB@57723|Acidobacteria	57723|Acidobacteria	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase22
SRR25158343_k127_2018762_20	204669.Acid345_1627	2.942e-202	640.0	COG0477@1|root,COG0477@2|Bacteria,3Y4JA@57723|Acidobacteria,2JJBX@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158343_k127_2018762_2	234267.Acid_1227	0.0	1145.0	COG1629@1|root,COG4771@2|Bacteria	234267.Acid_1227|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_9	234267.Acid_5957	1.541e-266	848.0	COG3250@1|root,COG3250@2|Bacteria,3Y3MQ@57723|Acidobacteria	57723|Acidobacteria	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
SRR25158343_k127_2018762_88	198214.SF3978	9.332e-39	146.0	COG3254@1|root,COG3254@2|Bacteria,1RGYV@1224|Proteobacteria,1S6AI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Involved in the anomeric conversion of L-rhamnose	rhaM	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
SRR25158343_k127_2018762_46	639030.JHVA01000001_gene2325	4.056e-132	430.0	COG4225@1|root,COG4225@2|Bacteria,3Y5S1@57723|Acidobacteria,2JMEP@204432|Acidobacteriia	204432|Acidobacteriia	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
SRR25158343_k127_2018762_19	761193.Runsl_2134	6.406e-204	645.0	COG4225@1|root,COG4225@2|Bacteria,4NH7G@976|Bacteroidetes,47N5K@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl Hydrolase Family 88	yteR_9	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88,Lipase_GDSL_2
SRR25158343_k127_2018762_67	1340493.JNIF01000003_gene1932	2.726e-75	261.0	COG2755@1|root,COG2755@2|Bacteria,3Y4BD@57723|Acidobacteria	57723|Acidobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_2018762_22	1267535.KB906767_gene1348	5.773e-197	628.0	COG3534@1|root,COG3534@2|Bacteria,3Y48A@57723|Acidobacteria,2JKQ1@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SRR25158343_k127_2018762_10	234267.Acid_7826	8.901e-259	816.0	COG1172@1|root,COG1879@1|root,COG1172@2|Bacteria,COG1879@2|Bacteria,3Y5DG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
SRR25158343_k127_2018762_58	886293.Sinac_6994	1.131e-104	349.0	COG1172@1|root,COG1172@2|Bacteria,2J3I0@203682|Planctomycetes	203682|Planctomycetes	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
SRR25158343_k127_2018762_24	886293.Sinac_6993	3.277e-192	614.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
SRR25158343_k127_2018762_96	1173028.ANKO01000220_gene584	9.511e-26	115.0	COG1556@1|root,COG1556@2|Bacteria	2|Bacteria	S	LUD domain	lldG	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158343_k127_2018762_42	134676.ACPL_4163	1.243e-138	455.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4D9WU@85008|Micromonosporales	201174|Actinobacteria	C	conserved protein containing a ferredoxin-like domain	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158343_k127_2018762_69	1236973.JCM9157_3129	3.745e-75	259.0	COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,1ZCUT@1386|Bacillus	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158343_k127_2018762_50	485913.Krac_4280	6.227e-117	392.0	COG1070@1|root,COG1070@2|Bacteria,2G61N@200795|Chloroflexi	200795|Chloroflexi	G	carbohydrate kinase FGGY	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158343_k127_2018762_28	1380391.JIAS01000012_gene4060	4.611e-185	588.0	COG4952@1|root,COG4952@2|Bacteria,1PSSV@1224|Proteobacteria,2TSCI@28211|Alphaproteobacteria,2JVQN@204441|Rhodospirillales	204441|Rhodospirillales	M	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_5	1396141.BATP01000004_gene5821	1.394e-316	984.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,46TRI@74201|Verrucomicrobia,2IU45@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158343_k127_2018762_37	1502852.FG94_00929	2.795e-147	506.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_7	1502852.FG94_00930	5.977e-279	893.0	COG3250@1|root,COG3250@2|Bacteria,1NTQW@1224|Proteobacteria	1224|Proteobacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_11	1134474.O59_002443	2.6e-254	812.0	COG2730@1|root,COG2730@2|Bacteria,1R2K4@1224|Proteobacteria,1SKI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
SRR25158343_k127_2018762_38	1304880.JAGB01000001_gene978	2.301e-146	474.0	COG1904@1|root,COG1904@2|Bacteria,1TR4T@1239|Firmicutes,249B2@186801|Clostridia	186801|Clostridia	G	glucuronate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_4	452637.Oter_1355	0.0	1045.0	COG3250@1|root,COG3250@2|Bacteria,46UWF@74201|Verrucomicrobia,3K7BB@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_33	1198114.AciX9_0613	1.572e-163	527.0	COG3669@1|root,COG3669@2|Bacteria,3Y417@57723|Acidobacteria,2JHNC@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
SRR25158343_k127_2018762_44	234267.Acid_4052	1.338e-135	443.0	COG2755@1|root,COG3401@1|root,COG2755@2|Bacteria,COG3401@2|Bacteria,3Y3K6@57723|Acidobacteria	57723|Acidobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_2018762_1	714943.Mucpa_5121	0.0	1284.0	COG3250@1|root,COG3250@2|Bacteria,4NHU5@976|Bacteroidetes,1IPCB@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2018762_55	497964.CfE428DRAFT_6556	3.561e-107	356.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
SRR25158343_k127_2018762_95	1340493.JNIF01000003_gene1932	2.377e-26	111.0	COG2755@1|root,COG2755@2|Bacteria,3Y4BD@57723|Acidobacteria	57723|Acidobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_2018762_43	1499967.BAYZ01000150_gene1713	2.791e-137	443.0	COG0667@1|root,COG0667@2|Bacteria,2NS4R@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	ydjG	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_2018762_36	204669.Acid345_4068	2.11e-150	503.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,3Y4B2@57723|Acidobacteria,2JJ4V@204432|Acidobacteriia	204432|Acidobacteriia	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
SRR25158343_k127_2018762_14	945713.IALB_2594	2.656e-250	797.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158343_k127_2018762_68	518766.Rmar_1735	2.802e-75	261.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,1FJUS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158343_k127_2018762_48	370438.PTH_2316	1.08e-128	424.0	COG2271@1|root,COG2271@2|Bacteria,1TS8X@1239|Firmicutes,24A85@186801|Clostridia,2646A@186807|Peptococcaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_2018762_80	493475.GARC_0477	4.566e-57	209.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria,1SAFU@1236|Gammaproteobacteria,468T4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158343_k127_2018762_3	861299.J421_0364	0.0	1049.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	yicI	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
SRR25158343_k127_2018762_97	545694.TREPR_1979	2.088e-24	117.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158343_k127_2018762_59	641526.ADIWIN_4052	1.863e-104	352.0	COG0189@1|root,COG0189@2|Bacteria,4PKRE@976|Bacteroidetes,1IJDG@117743|Flavobacteriia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,Dala_Dala_lig_C
SRR25158343_k127_2018762_89	638303.Thal_1251	9.695e-37	147.0	COG1994@1|root,COG1994@2|Bacteria,2G44C@200783|Aquificae	200783|Aquificae	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158343_k127_2018762_49	1304880.JAGB01000004_gene1402	2.188e-122	400.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158343_k127_2018762_8	1286632.P278_11120	7.607e-276	856.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158343_k127_2018762_112	880071.Fleli_0700	6.418e-07	51.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K00138,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158343_k127_2018762_114	1035308.AQYY01000001_gene2413	0.0007303	48.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
SRR25158343_k127_2018762_91	983917.RGE_12890	1.451e-34	140.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158343_k127_2018762_66	91464.S7335_2357	3.36e-79	271.0	COG2201@1|root,COG2201@2|Bacteria,1GJ7G@1117|Cyanobacteria,1H1FB@1129|Synechococcus	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158343_k127_2018762_94	1128427.KB904821_gene2463	3.183e-27	112.0	COG2201@1|root,COG2201@2|Bacteria,1G3H5@1117|Cyanobacteria,1HAH2@1150|Oscillatoriales	1117|Cyanobacteria	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
SRR25158343_k127_2018762_0	1128427.KB904821_gene2462	0.0	1287.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H91P@1150|Oscillatoriales	1117|Cyanobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158343_k127_2018762_56	760117.JN27_08235	6.445e-107	362.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158343_k127_2018762_84	1185876.BN8_02105	7.141e-53	188.0	COG3564@1|root,COG3564@2|Bacteria,4NQEN@976|Bacteroidetes,47QCQ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF779)	-	-	-	ko:K09959	-	-	-	-	ko00000	-	-	-	DUF779
SRR25158343_k127_2018762_99	945713.IALB_2785	5.427e-22	98.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SRR25158343_k127_2018762_98	1237149.C900_00817	2.84e-22	102.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158343_k127_2018762_87	1340493.JNIF01000004_gene492	1.689e-45	174.0	COG1354@1|root,COG1354@2|Bacteria,3Y458@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158343_k127_2018762_82	234267.Acid_6490	1.154e-53	194.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158343_k127_2018762_76	1536770.R50345_20995	2.045e-68	245.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,26QZR@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158343_k127_2018762_18	1034807.FBFL15_2178	9.931e-237	764.0	COG0827@1|root,COG1002@1|root,COG4096@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,COG4096@2|Bacteria,4PKGP@976|Bacteroidetes,1IJTP@117743|Flavobacteriia,2NWWD@237|Flavobacterium	976|Bacteroidetes	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase
SRR25158343_k127_2018762_108	1121288.AULL01000019_gene1523	1.126e-08	64.0	2ET0D@1|root,33KIK@2|Bacteria,4PQ24@976|Bacteroidetes,1IKYQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_110	1236959.BAMT01000001_gene1553	2.827e-07	57.0	28ZRX@1|root,2ZMGQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_111	479432.Sros_3771	4.634e-07	57.0	2BNAB@1|root,32GXX@2|Bacteria,2HF1P@201174|Actinobacteria,4EPYI@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158343_k127_2018762_81	861299.J421_2399	1.049e-55	198.0	COG1832@1|root,COG1832@2|Bacteria,1ZTUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158343_k127_2018762_34	1121895.Q765_20595	2.91e-156	501.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2NTJW@237|Flavobacterium	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_2018762_61	204669.Acid345_2365	3.186e-97	327.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria,2JHW8@204432|Acidobacteriia	204432|Acidobacteriia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158343_k127_2018762_85	891968.Anamo_2043	1.762e-48	176.0	COG0346@1|root,COG0346@2|Bacteria,3TAXT@508458|Synergistetes	508458|Synergistetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158343_k127_2018762_101	883103.HMPREF9703_00958	1.752e-18	99.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,27FYU@186828|Carnobacteriaceae	91061|Bacilli	M	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
SRR25158343_k127_2018762_74	1379270.AUXF01000006_gene81	1.405e-71	251.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158343_k127_2018762_106	204669.Acid345_0249	8.377e-14	78.0	2ER1F@1|root,33IKZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_105	1280954.HPO_18852	5.859e-14	76.0	2EAJ0@1|root,334MZ@2|Bacteria,1P8GP@1224|Proteobacteria,2UWW3@28211|Alphaproteobacteria,43ZP3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2018762_52	1170562.Cal6303_4353	2.325e-114	375.0	COG0005@1|root,COG0005@2|Bacteria,1G1F3@1117|Cyanobacteria,1HIDW@1161|Nostocales	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158343_k127_2018762_16	118163.Ple7327_2936	2.206e-239	749.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,3VIVK@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158343_k127_2063612_209	69395.JQLZ01000002_gene942	1.023e-20	91.0	COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,2TSU5@28211|Alphaproteobacteria,2KHY1@204458|Caulobacterales	204458|Caulobacterales	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158343_k127_2063612_24	1123276.KB893282_gene3958	5.207e-158	505.0	COG4225@1|root,COG4225@2|Bacteria,4NGSJ@976|Bacteroidetes,47MHQ@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
SRR25158343_k127_2063612_38	1254432.SCE1572_31930	1.147e-139	483.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,4389V@68525|delta/epsilon subdivisions,2X3J8@28221|Deltaproteobacteria,2YWAY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_2063612_135	234267.Acid_7677	6.833e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_2063612_90	450851.PHZ_c1673	8.02e-89	302.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_272	1301098.PKB_4630	0.0004367	49.0	2E3TX@1|root,32YRB@2|Bacteria,1NAJY@1224|Proteobacteria,1SDPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_34	864702.OsccyDRAFT_1653	1.249e-145	471.0	COG1192@1|root,COG1192@2|Bacteria,1G47J@1117|Cyanobacteria,1H9G5@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA,Mrr_cat
SRR25158343_k127_2063612_141	1195236.CTER_0234	5.351e-56	199.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158343_k127_2063612_163	861299.J421_1246	1.972e-41	155.0	2DMJC@1|root,32RYJ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4186)	yneG	-	-	-	-	-	-	-	-	-	-	-	DUF4186
SRR25158343_k127_2063612_123	1198114.AciX9_1370	1.124e-63	226.0	COG3544@1|root,COG3544@2|Bacteria,3Y4G7@57723|Acidobacteria,2JKAH@204432|Acidobacteriia	2|Bacteria	P	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158343_k127_2063612_7	1198114.AciX9_1369	6.709e-275	860.0	COG5276@1|root,COG5276@2|Bacteria,3Y393@57723|Acidobacteria,2JMHD@204432|Acidobacteriia	2|Bacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158343_k127_2063612_153	1034807.FBFL15_0871	4.737e-46	175.0	2CMH2@1|root,32SES@2|Bacteria,4NSUS@976|Bacteroidetes,1I479@117743|Flavobacteriia,2NUH7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_88	457424.BFAG_03104	3.597e-91	317.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	AAA_15,AAA_21,ABC_tran
SRR25158343_k127_2063612_171	1480694.DC28_03395	1.189e-36	150.0	2BDBG@1|root,32707@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4435)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4435
SRR25158343_k127_2063612_164	118168.MC7420_2001	1.334e-39	154.0	COG1661@1|root,COG1661@2|Bacteria,1G86Y@1117|Cyanobacteria,1HBMJ@1150|Oscillatoriales	1117|Cyanobacteria	S	DNA-binding protein with PD1-like DNA-binding motif	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR25158343_k127_2063612_243	314285.KT71_08625	8.862e-09	67.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,1S9I3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nuclease	Z012_04225	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
SRR25158343_k127_2063612_56	1379270.AUXF01000003_gene3841	1.545e-119	399.0	COG2204@1|root,COG2204@2|Bacteria,1ZUM4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_2063612_96	379066.GAU_2015	1.019e-85	308.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1ZTDZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SRR25158343_k127_2063612_249	1267535.KB906767_gene3598	4.235e-07	60.0	COG0760@1|root,COG0760@2|Bacteria,3Y4KY@57723|Acidobacteria	57723|Acidobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
SRR25158343_k127_2063612_133	1382359.JIAL01000001_gene1619	1.585e-58	229.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
SRR25158343_k127_2063612_19	234267.Acid_3898	1.084e-181	594.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158343_k127_2063612_232	204669.Acid345_2692	1.235e-12	81.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_145	903818.KI912268_gene1803	8.208e-52	189.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SRR25158343_k127_2063612_175	1081640.AGFU01000006_gene1131	2.26e-32	130.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,2K54X@204457|Sphingomonadales	204457|Sphingomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158343_k127_2063612_160	1185876.BN8_05709	6.265e-43	163.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,47Q5G@768503|Cytophagia	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158343_k127_2063612_47	204669.Acid345_2270	2.594e-126	414.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158343_k127_2063612_36	1379270.AUXF01000001_gene2673	2.549e-145	471.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158343_k127_2063612_65	1303518.CCALI_01492	7.166e-110	363.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158343_k127_2063612_108	292563.Cyast_2603	1.158e-75	261.0	COG0730@1|root,COG0730@2|Bacteria,1G8EH@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158343_k127_2063612_235	1303518.CCALI_01493	2.82e-11	76.0	2DS8I@1|root,33F02@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158343_k127_2063612_270	1121335.Clst_2266	0.0002321	53.0	2BZCW@1|root,32R4U@2|Bacteria,1V7B7@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158343_k127_2063612_244	1961.JOAK01000019_gene6959	1.851e-08	66.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158343_k127_2063612_119	330214.NIDE0244	3.179e-67	236.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158343_k127_2063612_116	1183438.GKIL_4241	3.209e-71	248.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158343_k127_2063612_11	1267535.KB906767_gene3266	1.892e-211	668.0	COG0364@1|root,COG0364@2|Bacteria,3Y2JZ@57723|Acidobacteria,2JHKE@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158343_k127_2063612_193	215803.DB30_5360	2.3e-25	113.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_241	1267535.KB906767_gene2173	6.066e-09	68.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_2063612_185	204669.Acid345_1725	6.199e-29	128.0	COG2885@1|root,COG2885@2|Bacteria,3Y7Y8@57723|Acidobacteria,2JMX3@204432|Acidobacteriia	204432|Acidobacteriia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158343_k127_2063612_29	204669.Acid345_4350	5.422e-153	504.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158343_k127_2063612_92	485913.Krac_11550	2.129e-88	297.0	COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi	200795|Chloroflexi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158343_k127_2063612_117	1123037.AUDE01000017_gene2509	2.909e-69	242.0	COG3647@1|root,COG3647@2|Bacteria,4NMNV@976|Bacteroidetes,1I1B4@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR25158343_k127_2063612_143	1189619.pgond44_14883	9.01e-53	190.0	COG4276@1|root,COG4276@2|Bacteria,4NQ3V@976|Bacteroidetes,1I398@117743|Flavobacteriia	976|Bacteroidetes	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_15	1267533.KB906738_gene2247	4.386e-189	609.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria,2JI4Z@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRR25158343_k127_2063612_21	883126.HMPREF9710_00804	1.205e-173	553.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2VIPV@28216|Betaproteobacteria,47455@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158343_k127_2063612_214	1163407.UU7_10740	4.133e-19	91.0	2CDT8@1|root,33C3R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_77	1210884.HG799470_gene14473	3.976e-100	336.0	COG4447@1|root,COG4447@2|Bacteria,2J0B6@203682|Planctomycetes	203682|Planctomycetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158343_k127_2063612_156	272134.KB731324_gene5504	1.108e-43	162.0	2CP0Z@1|root,32SI8@2|Bacteria,1G5TF@1117|Cyanobacteria,1HB85@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158343_k127_2063612_82	272134.KB731324_gene5503	2.606e-97	325.0	COG1718@1|root,COG1718@2|Bacteria,1G3HN@1117|Cyanobacteria,1H954@1150|Oscillatoriales	1117|Cyanobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_250	118168.MC7420_1191	1.854e-06	58.0	2F0RE@1|root,33TTT@2|Bacteria,1GDEI@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_94	99598.Cal7507_6086	1.779e-87	292.0	COG3548@1|root,COG3548@2|Bacteria,1GKP7@1117|Cyanobacteria,1HRK3@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158343_k127_2063612_27	483219.LILAB_29235	3.197e-155	503.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158343_k127_2063612_74	1122221.JHVI01000005_gene598	2.11e-100	372.0	COG1404@1|root,COG1404@2|Bacteria,1WIDU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	3.4.21.111	ko:K20754	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I9,Peptidase_S8
SRR25158343_k127_2063612_122	1124780.ANNU01000036_gene65	1.084e-63	223.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,47PQR@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158343_k127_2063612_97	349161.Dred_1897	1.709e-85	290.0	COG1208@1|root,COG1208@2|Bacteria,1TPII@1239|Firmicutes,249GT@186801|Clostridia,260FK@186807|Peptococcaceae	186801|Clostridia	JM	TIGRFAM Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR25158343_k127_2063612_73	1123372.AUIT01000018_gene1408	3.032e-102	342.0	COG0451@1|root,COG0451@2|Bacteria,2GHYT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_2063612_107	765420.OSCT_0947	5.02e-76	267.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158343_k127_2063612_35	118166.JH976537_gene4466	1.607e-145	466.0	COG0451@1|root,COG0451@2|Bacteria,1G3FQ@1117|Cyanobacteria,1H989@1150|Oscillatoriales	1117|Cyanobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158343_k127_2063612_142	1244869.H261_21733	5.016e-54	196.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,2JT4Q@204441|Rhodospirillales	204441|Rhodospirillales	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_6,Hydrolase_like,NTP_transferase
SRR25158343_k127_2063612_128	118166.JH976537_gene4467	4.282e-61	217.0	COG0279@1|root,COG0279@2|Bacteria,1G1I9@1117|Cyanobacteria,1HDBA@1150|Oscillatoriales	1117|Cyanobacteria	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_4,Glycos_transf_1,SIS_2
SRR25158343_k127_2063612_79	679926.Mpet_1390	4.91e-100	338.0	COG2605@1|root,arCOG01030@2157|Archaea	2157|Archaea	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158343_k127_2063612_87	237368.SCABRO_01358	1.013e-91	311.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158343_k127_2063612_49	32057.KB217478_gene1814	1.713e-121	404.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1HMN9@1161|Nostocales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158343_k127_2063612_224	207559.Dde_2894	2.229e-15	86.0	COG2242@1|root,COG2242@2|Bacteria,1MYGE@1224|Proteobacteria,42VGU@68525|delta/epsilon subdivisions,2WS5G@28221|Deltaproteobacteria,2M91U@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	TIGRFAM methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158343_k127_2063612_140	1038859.AXAU01000034_gene167	1.981e-56	205.0	COG1196@1|root,COG1196@2|Bacteria,1R4QE@1224|Proteobacteria,2UADP@28211|Alphaproteobacteria,3K1ZI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	D	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Methyltransf_21
SRR25158343_k127_2063612_14	497965.Cyan7822_5350	3.066e-190	601.0	COG0500@1|root,COG0500@2|Bacteria,1GHCT@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158343_k127_2063612_52	1094980.Mpsy_2369	2.332e-120	392.0	COG1089@1|root,arCOG01373@2157|Archaea,2Y39G@28890|Euryarchaeota,2NAJT@224756|Methanomicrobia	224756|Methanomicrobia	M	RmlD substrate binding domain	-	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_2063612_20	929562.Emtol_4288	1.029e-177	562.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,47K8D@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_2063612_111	720554.Clocl_1328	1.801e-75	265.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,3WGZX@541000|Ruminococcaceae	186801|Clostridia	M	MobA-like NTP transferase domain	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158343_k127_2063612_227	591158.SSMG_01301	1.117e-14	87.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycosyl transferase, group 1	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2063612_218	1122137.AQXF01000004_gene1770	1.973e-17	95.0	COG0438@1|root,COG0438@2|Bacteria,1NBMD@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158343_k127_2063612_130	755178.Cyan10605_1636	2.245e-59	214.0	COG0451@1|root,COG0451@2|Bacteria,1GB5V@1117|Cyanobacteria	1117|Cyanobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158343_k127_2063612_78	755178.Cyan10605_2797	4.533e-100	335.0	COG0451@1|root,COG0451@2|Bacteria,1GCZ0@1117|Cyanobacteria	1117|Cyanobacteria	GM	RmlD substrate binding domain	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158343_k127_2063612_205	420246.GTNG_3256	1.156e-21	106.0	COG1216@1|root,COG1216@2|Bacteria,1UVKN@1239|Firmicutes,4I2BN@91061|Bacilli,1WHQ2@129337|Geobacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158343_k127_2063612_58	313606.M23134_05412	4.379e-118	387.0	COG1086@1|root,COG1086@2|Bacteria,4NHN3@976|Bacteroidetes,47TXG@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
SRR25158343_k127_2063612_86	1267533.KB906735_gene4438	1.55e-93	312.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
SRR25158343_k127_2063612_158	580327.Tthe_1179	4.25e-43	171.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,25ESM@186801|Clostridia,42J83@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2063612_152	91464.S7335_1865	5.436e-47	180.0	COG1216@1|root,COG1216@2|Bacteria,1GQEZ@1117|Cyanobacteria,1H1HU@1129|Synechococcus	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2,Methyltransf_11,Methyltransf_23
SRR25158343_k127_2063612_127	1227500.C494_20178	2.534e-61	226.0	arCOG01405@1|root,arCOG01405@2157|Archaea	2157|Archaea	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2063612_207	580327.Tthe_2188	1.71e-21	105.0	COG2227@1|root,COG2227@2|Bacteria,1VI0K@1239|Firmicutes,24W90@186801|Clostridia	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158343_k127_2063612_221	489825.LYNGBM3L_52710	7.059e-16	88.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
SRR25158343_k127_2063612_112	1356852.N008_03895	2.454e-75	267.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158343_k127_2063612_230	580327.Tthe_0916	7.135e-14	84.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158343_k127_2063612_17	1499967.BAYZ01000026_gene1631	1.438e-186	601.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158343_k127_2063612_213	1121957.ATVL01000011_gene3612	2.619e-19	102.0	28YGT@1|root,2ZKB0@2|Bacteria,4P2Q1@976|Bacteroidetes,47UKX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_18	489825.LYNGBM3L_45070	2.892e-182	576.0	COG0399@1|root,COG0399@2|Bacteria,1G47X@1117|Cyanobacteria,1H9EC@1150|Oscillatoriales	1117|Cyanobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158343_k127_2063612_59	926569.ANT_20140	2.399e-117	386.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SRR25158343_k127_2063612_75	941449.dsx2_1094	2.215e-100	332.0	COG0500@1|root,COG2226@2|Bacteria,1N867@1224|Proteobacteria,4310U@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158343_k127_2063612_70	926569.ANT_20140	9.532e-107	355.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SRR25158343_k127_2063612_226	67281.JNZZ01000019_gene9	7.556e-15	84.0	COG0223@1|root,COG0223@2|Bacteria,2GN1Z@201174|Actinobacteria,417P8@629295|Streptomyces griseus group	201174|Actinobacteria	J	Formyl transferase, C-terminal domain	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158343_k127_2063612_132	1131269.AQVV01000005_gene375	1.226e-58	211.0	COG0224@1|root,COG0224@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
SRR25158343_k127_2063612_146	694427.Palpr_1146	2.339e-51	197.0	2E0I2@1|root,32W3U@2|Bacteria,4NTX5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_264	523850.TON_1631	0.0001395	53.0	COG0392@1|root,arCOG00899@2157|Archaea,2XTI1@28890|Euryarchaeota,243F4@183968|Thermococci	183968|Thermococci	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158343_k127_2063612_60	1173027.Mic7113_5256	1.266e-116	381.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158343_k127_2063612_53	330214.NIDE3016	3.382e-120	390.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158343_k127_2063612_115	1499967.BAYZ01000186_gene3970	1.867e-71	256.0	COG0438@1|root,COG0438@2|Bacteria,2NR2T@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2063612_51	439235.Dalk_0708	4.407e-121	410.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR25158343_k127_2063612_257	580340.Tlie_0365	8.326e-06	58.0	COG0457@1|root,COG0457@2|Bacteria	580340.Tlie_0365|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_183	671143.DAMO_2346	1.788e-29	134.0	COG0484@1|root,COG3307@1|root,COG0484@2|Bacteria,COG3307@2|Bacteria,2NPHS@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	DnaJ,Wzy_C
SRR25158343_k127_2063612_62	204669.Acid345_3614	5.196e-115	387.0	COG0128@1|root,COG0128@2|Bacteria,3Y3RH@57723|Acidobacteria,2JI7W@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158343_k127_2063612_200	926566.Terro_2783	1.208e-22	103.0	COG2172@1|root,COG2172@2|Bacteria,3Y4TY@57723|Acidobacteria,2JJGJ@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158343_k127_2063612_168	1382359.JIAL01000001_gene2134	1.881e-38	146.0	COG1366@1|root,COG1366@2|Bacteria,3Y4U6@57723|Acidobacteria,2JJH2@204432|Acidobacteriia	204432|Acidobacteriia	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158343_k127_2063612_229	1340493.JNIF01000003_gene4496	4.848e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IP@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158343_k127_2063612_196	551275.KB899549_gene772	1.886e-23	107.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,43XTC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158343_k127_2063612_170	1202532.FF52_18370	1.575e-37	144.0	COG1652@1|root,COG1652@2|Bacteria,4NNRS@976|Bacteroidetes,1I1Y9@117743|Flavobacteriia,2NZY8@237|Flavobacterium	976|Bacteroidetes	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158343_k127_2063612_33	189753.AXAS01000140_gene6011	1.683e-147	479.0	COG1311@1|root,COG1311@2|Bacteria,1NRUE@1224|Proteobacteria,2UPJ1@28211|Alphaproteobacteria,3K3MS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA-directed DNA polymerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_169	756883.Halar_0396	8.716e-38	151.0	28H56@1|root,2N557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_32	204669.Acid345_2370	4.499e-149	483.0	COG0304@1|root,COG0304@2|Bacteria,3Y43C@57723|Acidobacteria,2JMFI@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158343_k127_2063612_44	1120746.CCNL01000006_gene373	8.185e-129	422.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SRR25158343_k127_2063612_231	903818.KI912268_gene2695	3.772e-13	77.0	COG5652@1|root,COG5652@2|Bacteria,3Y82N@57723|Acidobacteria	57723|Acidobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158343_k127_2063612_271	501479.ACNW01000074_gene1905	0.0002392	47.0	2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,2UFRY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR25158343_k127_2063612_98	1340493.JNIF01000004_gene350	4.121e-85	290.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158343_k127_2063612_8	234267.Acid_0463	1.069e-237	743.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158343_k127_2063612_161	215803.DB30_0685	2.719e-42	158.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158343_k127_2063612_192	234267.Acid_0462	4.073e-26	114.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158343_k127_2063612_236	795359.TOPB45_1550	2.066e-10	69.0	COG0711@1|root,COG0711@2|Bacteria,2GHRB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158343_k127_2063612_274	102125.Xen7305DRAFT_00044300	0.0009013	48.0	COG0711@1|root,COG0711@2|Bacteria,1G6NA@1117|Cyanobacteria,3VK38@52604|Pleurocapsales	1117|Cyanobacteria	U	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria	atpG	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158343_k127_2063612_83	861299.J421_1261	1.483e-96	332.0	COG0612@1|root,COG0612@2|Bacteria,1ZT7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
SRR25158343_k127_2063612_57	861299.J421_1260	5.062e-119	399.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_2063612_131	163908.KB235896_gene2825	2.326e-59	214.0	COG0500@1|root,COG0500@2|Bacteria,1GQRZ@1117|Cyanobacteria,1HQI1@1161|Nostocales	1117|Cyanobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TPMT
SRR25158343_k127_2063612_39	1123073.KB899241_gene2108	6.088e-139	464.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,LTD
SRR25158343_k127_2063612_259	1499967.BAYZ01000124_gene2569	1.744e-05	56.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.40	ko:K05989,ko:K20541	-	-	-	-	ko00000,ko01000,ko02000	4.D.3.1.6	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,fn3
SRR25158343_k127_2063612_10	714943.Mucpa_4442	1.23e-211	673.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
SRR25158343_k127_2063612_9	234267.Acid_3143	2.357e-225	715.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158343_k127_2063612_6	1267535.KB906767_gene3806	3.889e-283	880.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158343_k127_2063612_179	1386089.N865_07060	1.669e-30	122.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4FHCP@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158343_k127_2063612_159	330214.NIDE1061	4.707e-43	162.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158343_k127_2063612_30	1340493.JNIF01000003_gene3112	1.578e-151	495.0	COG0029@1|root,COG0029@2|Bacteria,3Y39F@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158343_k127_2063612_71	1174528.JH992898_gene1315	5.202e-104	347.0	COG2367@1|root,COG2367@2|Bacteria,1G1KE@1117|Cyanobacteria,1JIXY@1189|Stigonemataceae	1117|Cyanobacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158343_k127_2063612_177	1121920.AUAU01000028_gene1383	5.242e-31	126.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158343_k127_2063612_134	1121904.ARBP01000009_gene4328	6.61e-58	227.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158343_k127_2063612_265	1205753.A989_01605	0.0001418	55.0	COG0726@1|root,COG0726@2|Bacteria,1RFCG@1224|Proteobacteria,1S808@1236|Gammaproteobacteria,1X451@135614|Xanthomonadales	135614|Xanthomonadales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158343_k127_2063612_113	1144275.COCOR_03283	3.525e-75	268.0	2EBW1@1|root,335VE@2|Bacteria,1NPNE@1224|Proteobacteria,432H3@68525|delta/epsilon subdivisions,2WXS6@28221|Deltaproteobacteria,2Z25U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_199	255470.cbdbA1523	8.996e-23	107.0	COG0515@1|root,COG0515@2|Bacteria	255470.cbdbA1523|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_181	1122169.AREN01000028_gene2879	5.073e-30	124.0	2DDSA@1|root,2ZJ2B@2|Bacteria,1QBI7@1224|Proteobacteria,1T73I@1236|Gammaproteobacteria,1JETT@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_42	1242864.D187_009322	4.936e-135	448.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2X9B9@28221|Deltaproteobacteria,2YX2A@29|Myxococcales	28221|Deltaproteobacteria	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158343_k127_2063612_157	861299.J421_2678	1.902e-43	161.0	COG3104@1|root,COG3104@2|Bacteria,1ZSRG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158343_k127_2063612_114	1121930.AQXG01000005_gene597	3.114e-73	254.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158343_k127_2063612_118	1267534.KB906756_gene632	6.451e-69	248.0	COG3437@1|root,COG3437@2|Bacteria,3Y2TI@57723|Acidobacteria,2JHKC@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
SRR25158343_k127_2063612_124	926559.JoomaDRAFT_0071	7.72e-63	226.0	29QDR@1|root,30BD1@2|Bacteria,4P01M@976|Bacteroidetes,1I7I4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_186	1385512.N784_12085	8.624e-29	121.0	2E5HE@1|root,3308U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_67	1385512.N784_12080	7.484e-108	375.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K03546	-	M00221	-	-	ko00000,ko00002,ko02000,ko03400	3.A.1.2	-	-	AAA_11,AAA_12,AAA_15,AAA_23,BPD_transp_2,DUF3732,IF2_N
SRR25158343_k127_2063612_89	867903.ThesuDRAFT_02222	7.316e-90	326.0	COG3378@1|root,COG5519@1|root,COG3378@2|Bacteria,COG5519@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia	186801|Clostridia	L	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
SRR25158343_k127_2063612_234	1120973.AQXL01000053_gene1853	1.793e-11	78.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	PriCT_2,Prim-Pol
SRR25158343_k127_2063612_245	1894.JOER01000072_gene7835	8.201e-08	63.0	2EI4I@1|root,33BVW@2|Bacteria,2IQR6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_191	1116375.VEJY3_04030	6.01e-27	126.0	COG3183@1|root,COG3183@2|Bacteria,1MZRA@1224|Proteobacteria,1SA0W@1236|Gammaproteobacteria,1XYI8@135623|Vibrionales	135623|Vibrionales	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR25158343_k127_2063612_91	796620.VIBC2010_09847	9.398e-89	310.0	COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,1SC80@1236|Gammaproteobacteria,1XZ99@135623|Vibrionales	135623|Vibrionales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
SRR25158343_k127_2063612_217	1123058.KB894266_gene1536	1.87e-17	90.0	COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,1I686@117743|Flavobacteriia	976|Bacteroidetes	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158343_k127_2063612_266	867902.Ornrh_1586	0.0001479	54.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	SpvB
SRR25158343_k127_2063612_195	880072.Desac_0543	4.902e-25	118.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,42Q95@68525|delta/epsilon subdivisions,2WKM2@28221|Deltaproteobacteria,2MS1I@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
SRR25158343_k127_2063612_155	1267533.KB906734_gene3891	1.829e-44	172.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158343_k127_2063612_54	945713.IALB_1039	4.139e-120	396.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SRR25158343_k127_2063612_50	204669.Acid345_1941	2.513e-121	396.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria,2JI2H@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158343_k127_2063612_5	760192.Halhy_4981	1.645e-293	914.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,1IR1K@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_2063612_26	667014.Thein_1915	5.508e-156	501.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158343_k127_2063612_84	525904.Tter_1437	9.519e-95	318.0	COG0345@1|root,COG0345@2|Bacteria,2NPIR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158343_k127_2063612_22	272134.KB731324_gene3218	5.764e-159	527.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MHYT,PAS,PAS_3,PAS_9
SRR25158343_k127_2063612_110	1183438.GKIL_2285	1.799e-75	261.0	COG0400@1|root,COG0400@2|Bacteria,1G3RX@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
SRR25158343_k127_2063612_126	1123278.KB893388_gene5681	4.8e-62	217.0	COG1247@1|root,COG1247@2|Bacteria,4NRD5@976|Bacteroidetes,47QE1@768503|Cytophagia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158343_k127_2063612_255	1123389.ATXJ01000005_gene1942	4.811e-06	54.0	2CFP7@1|root,33AK5@2|Bacteria,1WK2M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_228	2002.JOEQ01000009_gene6495	3.007e-14	78.0	COG1051@1|root,COG1051@2|Bacteria,2IIJJ@201174|Actinobacteria,4EJRA@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_2063612_166	234267.Acid_7287	5.248e-39	153.0	COG0461@1|root,COG0461@2|Bacteria,3Y6JQ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158343_k127_2063612_109	1267535.KB906767_gene4255	1.373e-75	259.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158343_k127_2063612_206	697281.Mahau_0162	1.682e-21	96.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,42GPV@68295|Thermoanaerobacterales	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158343_k127_2063612_1	504472.Slin_5713	0.0	1207.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	GRASP55_65,PD40,PDZ_2,Peptidase_S41,Tricorn_C1
SRR25158343_k127_2063612_46	1502852.FG94_02765	3.862e-127	420.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,476TQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_2063612_31	1502852.FG94_02765	1.871e-150	492.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,476TQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_2063612_165	1173023.KE650771_gene3319	2.901e-39	159.0	COG4977@1|root,COG4977@2|Bacteria,1G1HG@1117|Cyanobacteria,1JKB0@1189|Stigonemataceae	1117|Cyanobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC
SRR25158343_k127_2063612_136	179408.Osc7112_0047	2.37e-57	205.0	2B3ZT@1|root,31WPY@2|Bacteria,1GEG9@1117|Cyanobacteria	1117|Cyanobacteria	S	SMI1 / KNR4 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_242	583345.Mmol_0910	8.654e-09	65.0	COG0438@1|root,COG0457@1|root,COG3914@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,2KMDJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,Methyltransf_12,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_2063612_202	204669.Acid345_3339	2.46e-22	102.0	2DB97@1|root,32TX2@2|Bacteria,3Y59S@57723|Acidobacteria,2JJUG@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_45	1123023.JIAI01000001_gene7663	2.358e-127	426.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4E1JQ@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158343_k127_2063612_174	318161.Sden_2488	5.48e-34	136.0	COG0454@1|root,COG0456@2|Bacteria,1N506@1224|Proteobacteria,1S97J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_2063612_104	1218103.CIN01S_12_00170	2.016e-77	263.0	COG1670@1|root,COG1670@2|Bacteria,4NM3W@976|Bacteroidetes,1I1MN@117743|Flavobacteriia,3ZSTN@59732|Chryseobacterium	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158343_k127_2063612_99	28072.Nos7524_2690	5.228e-85	288.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1HK26@1161|Nostocales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158343_k127_2063612_197	240016.ABIZ01000001_gene103	2.066e-23	105.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_85	649638.Trad_2457	5.626e-94	316.0	COG4711@1|root,COG4711@2|Bacteria,1WMQT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative integral membrane protein (DUF2391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2391
SRR25158343_k127_2063612_12	909663.KI867150_gene1794	5.541e-210	672.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MQD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158343_k127_2063612_93	398512.JQKC01000038_gene4565	4.457e-88	307.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,24DGJ@186801|Clostridia,3WQGW@541000|Ruminococcaceae	186801|Clostridia	S	HD domain	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158343_k127_2063612_194	398512.JQKC01000038_gene4566	4.436e-25	111.0	COG3465@1|root,COG3465@2|Bacteria,1VHV4@1239|Firmicutes,25AY4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K09388	-	-	-	-	ko00000	-	-	-	-
SRR25158343_k127_2063612_69	525373.HMPREF0766_14337	4.537e-107	349.0	COG1961@1|root,COG1961@2|Bacteria,4NJM8@976|Bacteroidetes,1ITQV@117747|Sphingobacteriia	976|Bacteroidetes	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR25158343_k127_2063612_80	888059.HMPREF9071_1751	5.594e-100	334.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia,1ERT1@1016|Capnocytophaga	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
SRR25158343_k127_2063612_154	395493.BegalDRAFT_3288	5.179e-46	169.0	COG0827@1|root,COG0827@2|Bacteria,1MVG5@1224|Proteobacteria	1224|Proteobacteria	LV	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
SRR25158343_k127_2063612_198	1122621.ATZA01000101_gene1491	4.543e-23	100.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1IS5H@117747|Sphingobacteriia	976|Bacteroidetes	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
SRR25158343_k127_2063612_3	395493.BegalDRAFT_3287	0.0	1069.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1MVG5@1224|Proteobacteria,1SZ1A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	TaqI-like C-terminal specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
SRR25158343_k127_2063612_76	1444712.BN1013_02446	3.344e-100	331.0	COG4185@1|root,COG4185@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
SRR25158343_k127_2063612_215	706587.Desti_5179	8.476e-19	87.0	2EH1B@1|root,33ATB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_0	880073.Calab_3102	0.0	1637.0	COG0553@1|root,COG3886@1|root,COG0553@2|Bacteria,COG3886@2|Bacteria,2NQHS@2323|unclassified Bacteria	2|Bacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII,SNF2_N
SRR25158343_k127_2063612_72	266264.Rmet_2670	2.619e-102	347.0	COG2189@1|root,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158343_k127_2063612_187	1537917.JU82_07710	4.392e-28	115.0	2AM36@1|root,31BX9@2|Bacteria,1P030@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_204	1304885.AUEY01000062_gene2641	8.998e-22	102.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158343_k127_2063612_240	1230342.CTM_17177	2.931e-09	63.0	COG1396@1|root,COG1396@2|Bacteria,1VG62@1239|Firmicutes,24NEA@186801|Clostridia,36KT5@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
SRR25158343_k127_2063612_2	526227.Mesil_0570	0.0	1139.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria	2|Bacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_11,AAA_12,AAA_30,PDDEXK_1,UvrD_C_2,Viral_helicase1
SRR25158343_k127_2063612_105	234267.Acid_2524	7.51e-77	270.0	2E0FE@1|root,32W1M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
SRR25158343_k127_2063612_43	402881.Plav_0314	7.79e-130	426.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,2U47U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
SRR25158343_k127_2063612_100	1122173.AXVL01000018_gene452	5.689e-85	291.0	COG0863@1|root,COG0863@2|Bacteria,37A63@32066|Fusobacteria	32066|Fusobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158343_k127_2063612_268	1122917.KB899685_gene3231	0.0001671	49.0	COG1522@1|root,COG1522@2|Bacteria,1VVNW@1239|Firmicutes,4HWH8@91061|Bacilli,26XQT@186822|Paenibacillaceae	91061|Bacilli	K	sequence-specific DNA binding	xkdB	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_66	1340493.JNIF01000003_gene3183	1.02e-108	399.0	COG3209@1|root,COG3209@2|Bacteria,3Y7FC@57723|Acidobacteria	57723|Acidobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158343_k127_2063612_220	700598.Niako_5053	3.362e-16	90.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158343_k127_2063612_260	1340493.JNIF01000003_gene2904	3.759e-05	52.0	COG3209@1|root,COG3209@2|Bacteria,3Y5MY@57723|Acidobacteria	57723|Acidobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_248	1396418.BATQ01000172_gene2884	3.193e-07	56.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158343_k127_2063612_246	1207055.C100_22570	1.175e-07	66.0	2C9DE@1|root,2Z8R4@2|Bacteria,1NVMQ@1224|Proteobacteria,2U51M@28211|Alphaproteobacteria,2K0UF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_251	935948.KE386494_gene78	2.243e-06	57.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,42G7Y@68295|Thermoanaerobacterales	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158343_k127_2063612_201	1265502.KB905949_gene940	1.826e-22	98.0	2DSQC@1|root,33H1C@2|Bacteria,1NCJN@1224|Proteobacteria,2W3WE@28216|Betaproteobacteria,4AIA0@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_190	1122915.AUGY01000041_gene821	3.077e-27	113.0	2EHP8@1|root,33BF1@2|Bacteria	2|Bacteria	S	Multiubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	Multi_ubiq
SRR25158343_k127_2063612_28	1122915.AUGY01000041_gene822	4e-154	496.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158343_k127_2063612_139	1122915.AUGY01000041_gene823	6.302e-57	200.0	2BWTI@1|root,32SZZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_63	391626.OAN307_c31540	9.655e-112	379.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_2063612_219	1047013.AQSP01000118_gene1263	1.963e-16	86.0	COG0817@1|root,COG0817@2|Bacteria	2|Bacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158343_k127_2063612_262	402881.Plav_0322	0.0001023	50.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158343_k127_2063612_167	1033743.CAES01000002_gene1810	7.253e-39	160.0	COG0715@1|root,COG0715@2|Bacteria,1TRYN@1239|Firmicutes,4I97Z@91061|Bacilli,2715F@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158343_k127_2063612_147	1235799.C818_00853	6.934e-51	190.0	COG0600@1|root,COG0600@2|Bacteria,1V3NA@1239|Firmicutes,24G03@186801|Clostridia,27MWT@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158343_k127_2063612_120	543728.Vapar_5516	7.353e-66	234.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,4ACPW@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158343_k127_2063612_273	1033743.CAES01000002_gene1810	0.0008169	51.0	COG0715@1|root,COG0715@2|Bacteria,1TRYN@1239|Firmicutes,4I97Z@91061|Bacilli,2715F@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158343_k127_2063612_144	46234.ANA_C11797	2.424e-52	201.0	28K4Y@1|root,2Z9TT@2|Bacteria,1G1ES@1117|Cyanobacteria	1117|Cyanobacteria	-	-	mcnG	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_137	1343740.M271_28670	4.259e-57	207.0	COG3382@1|root,COG3382@2|Bacteria,2GMX2@201174|Actinobacteria	201174|Actinobacteria	S	B3 4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
SRR25158343_k127_2063612_225	1173022.Cri9333_0591	2.953e-15	85.0	2EDSP@1|root,337N3@2|Bacteria,1GA9F@1117|Cyanobacteria,1HFTJ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_13	1173022.Cri9333_0588	2.497e-195	625.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF3631
SRR25158343_k127_2063612_68	1173022.Cri9333_0587	3.517e-107	359.0	COG0399@1|root,COG0399@2|Bacteria,1GF8X@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158343_k127_2063612_121	1307759.JOMJ01000003_gene1324	1.14e-65	236.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42QHV@68525|delta/epsilon subdivisions,2WK71@28221|Deltaproteobacteria,2MBCK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158343_k127_2063612_23	1250005.PHEL85_3386	4.045e-158	537.0	COG0433@1|root,COG0433@2|Bacteria,4NVJM@976|Bacteroidetes,1I7IY@117743|Flavobacteriia,3VX4H@52959|Polaribacter	976|Bacteroidetes	S	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
SRR25158343_k127_2063612_150	1047013.AQSP01000109_gene2428	2.297e-49	190.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158343_k127_2063612_178	1047013.AQSP01000109_gene2428	9.56e-31	136.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158343_k127_2063612_233	1280.SAXN108_2120	1.619e-12	75.0	COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HNDI@91061|Bacilli,4GZ2R@90964|Staphylococcaceae	91061|Bacilli	L	terminase small subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
SRR25158343_k127_2063612_64	56780.SYN_02041	1.749e-110	361.0	28IYQ@1|root,2Z8WB@2|Bacteria,1MY3Q@1224|Proteobacteria	1224|Proteobacteria	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
SRR25158343_k127_2063612_41	946483.Cenrod_2479	1.03e-135	437.0	COG0863@1|root,COG0863@2|Bacteria,1P97D@1224|Proteobacteria,2WGY7@28216|Betaproteobacteria,4AJZW@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158343_k127_2063612_148	278963.ATWD01000002_gene345	7.681e-51	191.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
SRR25158343_k127_2063612_81	867903.ThesuDRAFT_02222	3.4e-99	355.0	COG3378@1|root,COG5519@1|root,COG3378@2|Bacteria,COG5519@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia	186801|Clostridia	L	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
SRR25158343_k127_2063612_239	1094508.Tsac_1081	1.522e-09	72.0	COG3378@1|root,COG3378@2|Bacteria,1U5Q1@1239|Firmicutes,24M6G@186801|Clostridia	186801|Clostridia	S	Phage plasmid primase P4 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_172	1123037.AUDE01000048_gene482	1.942e-36	156.0	COG0265@1|root,COG0265@2|Bacteria,4NPPM@976|Bacteroidetes,1I66Q@117743|Flavobacteriia	976|Bacteroidetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
SRR25158343_k127_2063612_252	888059.HMPREF9071_1199	2.482e-06	60.0	COG3209@1|root,COG3209@2|Bacteria,4PHY2@976|Bacteroidetes,1IDNE@117743|Flavobacteriia,1EQ7G@1016|Capnocytophaga	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_173	313628.LNTAR_15097	3.744e-35	140.0	2DZEP@1|root,32V8S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_103	1117315.AHCA01000003_gene188	7.585e-78	281.0	COG4928@1|root,COG4928@2|Bacteria,1RBWH@1224|Proteobacteria,1S7YY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
SRR25158343_k127_2063612_102	1121472.AQWN01000003_gene1538	3.476e-79	272.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158343_k127_2063612_48	1341151.ASZU01000026_gene1120	1.346e-121	398.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,27BEG@186824|Thermoactinomycetaceae	91061|Bacilli	O	Pyridine nucleotide-disulphide oxidoreductase	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_2063612_138	375286.mma_3637	4.64e-57	205.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2VRSU@28216|Betaproteobacteria,474F4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Lipocalin-like domain	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
SRR25158343_k127_2063612_210	667014.Thein_0931	4.086e-20	93.0	COG2331@1|root,COG2331@2|Bacteria,2GI3F@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158343_k127_2063612_222	204669.Acid345_3561	1.53e-15	87.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_2063612_208	1336208.JADY01000029_gene2312	3.365e-21	107.0	COG2885@1|root,COG2885@2|Bacteria,1N4QS@1224|Proteobacteria	1224|Proteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
SRR25158343_k127_2063612_188	743721.Psesu_1609	6.753e-28	120.0	COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria,1TAFV@1236|Gammaproteobacteria,1X74T@135614|Xanthomonadales	135614|Xanthomonadales	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
SRR25158343_k127_2063612_25	933262.AXAM01000003_gene2875	6.252e-158	520.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2MIIX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158343_k127_2063612_37	234267.Acid_3898	7.372e-144	482.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158343_k127_2063612_211	196490.AUEZ01000008_gene5433	1.416e-19	92.0	2BTH2@1|root,32NPE@2|Bacteria,1P4VQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_61	700598.Niako_5168	5.656e-116	382.0	COG5549@1|root,COG5549@2|Bacteria,4PKRA@976|Bacteroidetes,1J0TR@117747|Sphingobacteriia	976|Bacteroidetes	O	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
SRR25158343_k127_2063612_40	272123.Anacy_0228	8.467e-136	471.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158343_k127_2063612_216	388467.A19Y_2252	1.091e-18	100.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G3QU@1117|Cyanobacteria,1HAPS@1150|Oscillatoriales	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PPC,Peptidase_C11
SRR25158343_k127_2063612_256	595536.ADVE02000002_gene4118	6.591e-06	53.0	COG2801@1|root,COG2801@2|Bacteria,1NEIM@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_149	1469607.KK073768_gene1853	7.034e-50	194.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HMGW@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158343_k127_2063612_95	357808.RoseRS_3131	3.112e-87	311.0	COG3903@1|root,COG3903@2|Bacteria,2G8KB@200795|Chloroflexi	200795|Chloroflexi	K	NB-ARC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,NB-ARC,TPR_12
SRR25158343_k127_2063612_182	1173022.Cri9333_3090	1.724e-29	136.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1H73P@1150|Oscillatoriales	1117|Cyanobacteria	KLT	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,Guanylate_cyc
SRR25158343_k127_2063612_151	1173028.ANKO01000195_gene5937	8.401e-49	198.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
SRR25158343_k127_2063612_176	1469607.KK073768_gene1426	2.374e-31	142.0	COG1075@1|root,COG4249@1|root,COG1075@2|Bacteria,COG4249@2|Bacteria,1G42B@1117|Cyanobacteria,1HPW7@1161|Nostocales	1117|Cyanobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	LCAT,Peptidase_C14
SRR25158343_k127_2063612_55	99598.Cal7507_3400	4.806e-120	428.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_12,TPR_7,TPR_8
SRR25158343_k127_2063612_263	1499967.BAYZ01000009_gene5337	0.0001042	53.0	2EKNX@1|root,33ECP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_261	717606.PaecuDRAFT_4452	3.816e-05	53.0	COG4193@1|root,COG4193@2|Bacteria	2|Bacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,Glucosaminidase,NLPC_P60,Peptidase_C39_2,SLH
SRR25158343_k127_2063612_258	944560.HMPREF9058_0151	8.869e-06	58.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria,4D3A2@85005|Actinomycetales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TrwB_AAD_bind
SRR25158343_k127_2063612_203	686340.Metal_4003	3.924e-22	98.0	2E3RU@1|root,32YPG@2|Bacteria,1NAWV@1224|Proteobacteria,1TC7Q@1236|Gammaproteobacteria,1XGPB@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2063612_106	1492737.FEM08_26930	7.786e-77	261.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia,2NVHB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	CHB_HEX_C_1,DUF4982,Fn3_assoc,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2063612_4	1492737.FEM08_26930	0.0	1053.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia,2NVHB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	CHB_HEX_C_1,DUF4982,Fn3_assoc,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158343_k127_2063612_189	394.NGR_a01960	1.65e-27	117.0	29W4Y@1|root,30HPW@2|Bacteria,1PAEP@1224|Proteobacteria,2UYIS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158343_k127_2063612_101	290399.Arth_4482	2.72e-82	297.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-E2_A,Prok-E2_B,Prok-JAB,ThiF
SRR25158343_k127_2063612_125	658187.LDG_5780	3.717e-62	219.0	COG1961@1|root,COG1961@2|Bacteria,1RA0V@1224|Proteobacteria,1RPSK@1236|Gammaproteobacteria,1JGHE@118969|Legionellales	118969|Legionellales	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
SRR25158343_k127_2063612_212	379066.GAU_3762	1.854e-19	105.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SRR25158343_k127_2063612_247	1267005.KB911255_gene3062	1.731e-07	65.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Big_1,CHU_C,Peptidase_S74,SLH
SRR25158343_k127_2063612_254	391598.FBBAL38_10042	4.329e-06	51.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158343_k127_2063612_16	204669.Acid345_4392	5.026e-188	622.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158343_k127_2089998_145	1379270.AUXF01000003_gene3855	2.063e-38	146.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158343_k127_2089998_32	204669.Acid345_0710	3.76e-133	435.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria,2JMAK@204432|Acidobacteriia	204432|Acidobacteriia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
SRR25158343_k127_2089998_8	1267535.KB906767_gene3340	3.791e-212	665.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158343_k127_2089998_13	760568.Desku_1668	3.695e-187	599.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158343_k127_2089998_214	997296.PB1_14964	9.193e-05	55.0	COG3330@1|root,COG3330@2|Bacteria,1V2ZT@1239|Firmicutes,4I257@91061|Bacilli,1ZG55@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912
SRR25158343_k127_2089998_187	243231.GSU0673	3.935e-14	82.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria,43VBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158343_k127_2089998_126	1123288.SOV_3c03480	1.659e-46	181.0	COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,4H25K@909932|Negativicutes	909932|Negativicutes	M	lipopolysaccharide heptosyltransferase	rfaF	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158343_k127_2089998_121	215803.DB30_7594	3.783e-50	190.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SRR25158343_k127_2089998_78	1260356.D920_01497	1.984e-81	282.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,4B00D@81852|Enterococcaceae	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRR25158343_k127_2089998_25	760142.Hipma_0864	6.881e-143	485.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2M6ZV@213113|Desulfurellales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158343_k127_2089998_195	285535.JOEY01000033_gene9350	3.843e-12	77.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_2089998_189	102125.Xen7305DRAFT_00033220	4.796e-14	83.0	COG3452@1|root,COG5002@1|root,COG3452@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158343_k127_2089998_44	1094980.Mpsy_3113	3.49e-115	377.0	COG0714@1|root,arCOG00441@2157|Archaea,2Y6X0@28890|Euryarchaeota,2NAEY@224756|Methanomicrobia	224756|Methanomicrobia	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
SRR25158343_k127_2089998_108	1134912.AJTV01000002_gene1748	2.615e-59	215.0	2AC8B@1|root,311T0@2|Bacteria,1NK0P@1224|Proteobacteria,2VD5M@28211|Alphaproteobacteria,3713U@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_150	160799.PBOR_16515	7.967e-35	136.0	COG0457@1|root,COG0457@2|Bacteria,1VDZT@1239|Firmicutes,4HX3R@91061|Bacilli,26Z1E@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_68	1267535.KB906767_gene4333	1.474e-88	318.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria,2JI5M@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
SRR25158343_k127_2089998_1	1340493.JNIF01000004_gene626	1.224e-317	1009.0	COG1629@1|root,COG4771@2|Bacteria,3Y6GV@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_2089998_151	1123242.JH636434_gene3566	2.213e-33	143.0	COG0613@1|root,COG0613@2|Bacteria,2J1VB@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_184	404589.Anae109_0108	5.276e-15	80.0	COG4627@1|root,COG4627@2|Bacteria,1N8RI@1224|Proteobacteria,43BG0@68525|delta/epsilon subdivisions,2X6UB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158343_k127_2089998_140	448385.sce1328	2.504e-40	154.0	COG4276@1|root,COG4276@2|Bacteria,1R0BS@1224|Proteobacteria,43CU7@68525|delta/epsilon subdivisions,2X81U@28221|Deltaproteobacteria,2Z3JC@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158343_k127_2089998_148	380358.XALC_2740	2.536e-35	145.0	COG1331@1|root,COG1331@2|Bacteria,1QWIF@1224|Proteobacteria,1T2VZ@1236|Gammaproteobacteria,1XD6X@135614|Xanthomonadales	135614|Xanthomonadales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
SRR25158343_k127_2089998_19	945713.IALB_2412	3.112e-167	539.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	ddc	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158343_k127_2089998_37	1379698.RBG1_1C00001G1351	3.605e-126	417.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158343_k127_2089998_56	1396418.BATQ01000104_gene5463	4.016e-98	329.0	COG0559@1|root,COG0559@2|Bacteria,46UCA@74201|Verrucomicrobia,2IVC6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158343_k127_2089998_60	1379698.RBG1_1C00001G1349	4.134e-94	322.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158343_k127_2089998_61	1157490.EL26_09475	5.37e-94	314.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,2781Z@186823|Alicyclobacillaceae	91061|Bacilli	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158343_k127_2089998_66	626939.HMPREF9443_01167	4.063e-91	305.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4H223@909932|Negativicutes	909932|Negativicutes	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158343_k127_2089998_179	82996.sch_05285	4.562e-18	99.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,3ZZJF@613|Serratia	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158343_k127_2089998_69	485913.Krac_3712	3.634e-88	302.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158343_k127_2089998_213	207954.MED92_01104	5.999e-05	55.0	COG4254@1|root,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,1XNT0@135619|Oceanospirillales	135619|Oceanospirillales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158343_k127_2089998_81	1348908.KI518586_gene3086	1.823e-77	270.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,1ZB56@1386|Bacillus	91061|Bacilli	P	COG1230 Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158343_k127_2089998_80	443144.GM21_0578	3.319e-79	279.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43B2T@68525|delta/epsilon subdivisions,2X6GN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	larA	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158343_k127_2089998_112	504472.Slin_7046	3.32e-53	192.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,47MUD@768503|Cytophagia	976|Bacteroidetes	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158343_k127_2089998_9	1121015.N789_06360	2.091e-206	664.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria,1X44S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158343_k127_2089998_20	1121015.N789_06355	4.208e-154	497.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RP7V@1236|Gammaproteobacteria,1X42N@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158343_k127_2089998_135	404380.Gbem_1026	1.468e-42	165.0	COG0500@1|root,COG2226@2|Bacteria,1QYSR@1224|Proteobacteria,42Z2G@68525|delta/epsilon subdivisions,2WUBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_73	1242864.D187_000461	8.999e-84	299.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales	28221|Deltaproteobacteria	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
SRR25158343_k127_2089998_209	700598.Niako_2496	5.126e-06	52.0	COG1359@1|root,COG1359@2|Bacteria,4P3Z8@976|Bacteroidetes	976|Bacteroidetes	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_39	1120705.FG95_00881	8.111e-120	397.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TQRF@28211|Alphaproteobacteria,2KD3V@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_2089998_117	1254432.SCE1572_45490	4.558e-51	188.0	COG3409@1|root,COG3409@2|Bacteria,1Q95M@1224|Proteobacteria,43760@68525|delta/epsilon subdivisions,2X24E@28221|Deltaproteobacteria,2Z001@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_57	1541065.JRFE01000024_gene1143	5.161e-98	329.0	COG0053@1|root,COG0053@2|Bacteria,1G361@1117|Cyanobacteria,3VM1Q@52604|Pleurocapsales	1117|Cyanobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158343_k127_2089998_154	1121091.AUMP01000006_gene4215	1.126e-31	129.0	COG2318@1|root,COG2318@2|Bacteria,1VC1G@1239|Firmicutes,4HMPJ@91061|Bacilli	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_2089998_5	1499967.BAYZ01000182_gene4414	1.396e-243	769.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158343_k127_2089998_107	290397.Adeh_3744	1.474e-60	213.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158343_k127_2089998_183	297246.lpp2475	5.069e-15	82.0	2C50I@1|root,33MW9@2|Bacteria,1QBED@1224|Proteobacteria,1T7I0@1236|Gammaproteobacteria,1JFEI@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_185	457396.CSBG_00702	6.143e-15	82.0	COG0749@1|root,COG0749@2|Bacteria,1TT5M@1239|Firmicutes,248J9@186801|Clostridia,36IN9@31979|Clostridiaceae	186801|Clostridia	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A,DNA_pol_A_exo1
SRR25158343_k127_2089998_109	452637.Oter_3715	1.565e-56	204.0	COG3132@1|root,COG3132@2|Bacteria,46VIH@74201|Verrucomicrobia,3K85I@414999|Opitutae	414999|Opitutae	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SRR25158343_k127_2089998_156	483219.LILAB_07800	8.276e-31	135.0	COG4219@1|root,COG4219@2|Bacteria,1P0K4@1224|Proteobacteria	1224|Proteobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_101	1380390.JIAT01000009_gene362	1.506e-64	233.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158343_k127_2089998_67	746697.Aeqsu_1198	6.519e-90	310.0	COG1331@1|root,COG1331@2|Bacteria,4NIPN@976|Bacteroidetes,1HZZV@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
SRR25158343_k127_2089998_129	635013.TherJR_2128	6.099e-45	185.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158343_k127_2089998_203	909943.HIMB100_00007280	5.999e-09	66.0	2DBSD@1|root,2ZARI@2|Bacteria,1MX0F@1224|Proteobacteria,2TUNC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
SRR25158343_k127_2089998_54	330214.NIDE2011	4.346e-103	354.0	COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria	2|Bacteria	S	type VI secretion protein	sciH	-	-	ko:K11900,ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
SRR25158343_k127_2089998_96	1121895.Q765_17990	5.35e-67	236.0	COG3361@1|root,COG3361@2|Bacteria,4NITY@976|Bacteroidetes,1I0CJ@117743|Flavobacteriia,2NUTU@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158343_k127_2089998_50	1120977.JHUX01000003_gene2072	4.483e-107	356.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,3NKAC@468|Moraxellaceae	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
SRR25158343_k127_2089998_82	1499967.BAYZ01000014_gene6405	2.053e-77	270.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
SRR25158343_k127_2089998_113	1499967.BAYZ01000014_gene6406	1.451e-52	194.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158343_k127_2089998_46	1123073.KB899241_gene2080	6.362e-110	364.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XCJS@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_2089998_12	1173029.JH980292_gene420	4.633e-188	606.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158343_k127_2089998_6	1411123.JQNH01000001_gene261	4.275e-243	764.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TT2P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	elongator protein 3 miab nifb	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158343_k127_2089998_141	1296416.JACB01000004_gene1133	2.776e-40	156.0	COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,1I2P2@117743|Flavobacteriia,2YIQT@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158343_k127_2089998_49	234267.Acid_3898	2.307e-108	377.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158343_k127_2089998_164	204669.Acid345_2150	2.4e-28	120.0	2DMJE@1|root,32RYR@2|Bacteria,3Y4XN@57723|Acidobacteria,2JJFS@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SRR25158343_k127_2089998_162	96561.Dole_1383	8.013e-29	121.0	2AFH8@1|root,315HQ@2|Bacteria,1Q8KQ@1224|Proteobacteria,432Q5@68525|delta/epsilon subdivisions,2WY4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_200	215803.DB30_3743	6.399e-10	61.0	2ANK2@1|root,31DJ5@2|Bacteria,1QAV5@1224|Proteobacteria,435BD@68525|delta/epsilon subdivisions,2WZNS@28221|Deltaproteobacteria,2Z2FM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_204	215803.DB30_3744	8.694e-09	59.0	2BQRB@1|root,32JMY@2|Bacteria,1PDGZ@1224|Proteobacteria,435GN@68525|delta/epsilon subdivisions,2WZU3@28221|Deltaproteobacteria,2Z2RN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_125	926549.KI421517_gene1746	4.463e-47	193.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
SRR25158343_k127_2089998_197	243090.RB7985	2.112e-11	71.0	COG1446@1|root,COG4319@1|root,COG1446@2|Bacteria,COG4319@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
SRR25158343_k127_2089998_188	1078085.HMPREF1210_03371	4.64e-14	78.0	2E9CG@1|root,333K5@2|Bacteria,1V87Y@1239|Firmicutes,4HIGZ@91061|Bacilli,26FG7@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIMP
SRR25158343_k127_2089998_165	204669.Acid345_4518	7.893e-28	116.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia	204432|Acidobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158343_k127_2089998_133	1121481.AUAS01000006_gene880	2.56e-43	171.0	COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes,47JW0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158343_k127_2089998_205	644282.Deba_2010	1.377e-08	63.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084,ko:K06888	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158343_k127_2089998_77	1267535.KB906767_gene1613	8.154e-82	285.0	COG0820@1|root,COG0820@2|Bacteria,3Y3HQ@57723|Acidobacteria,2JIT9@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158343_k127_2089998_92	1519464.HY22_05890	3.122e-69	245.0	COG1864@1|root,COG1864@2|Bacteria,1FFIK@1090|Chlorobi	1090|Chlorobi	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
SRR25158343_k127_2089998_122	1403819.BATR01000118_gene4062	3.47e-49	179.0	COG4276@1|root,COG4276@2|Bacteria,46W6H@74201|Verrucomicrobia,2IUR6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_26	1408445.JHXP01000015_gene3465	1.211e-140	466.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_12,Methyltransf_23
SRR25158343_k127_2089998_79	269797.Mbar_A0237	5.062e-81	281.0	COG0463@1|root,arCOG01381@2157|Archaea,2XYGG@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_2089998_30	867845.KI911784_gene1207	6.866e-135	441.0	COG1134@1|root,COG1134@2|Bacteria,2G7ZX@200795|Chloroflexi,3772I@32061|Chloroflexia	32061|Chloroflexia	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
SRR25158343_k127_2089998_84	237368.SCABRO_01358	5.288e-76	266.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158343_k127_2089998_166	565033.GACE_1131	1.075e-27	124.0	COG0463@1|root,arCOG01381@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_2089998_100	1123277.KB893244_gene5128	7.797e-65	236.0	COG0438@1|root,COG0438@2|Bacteria,4NIV3@976|Bacteroidetes,47P66@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_2089998_119	1121405.dsmv_2878	1.217e-50	194.0	COG0438@1|root,COG0438@2|Bacteria,1N8I7@1224|Proteobacteria,430YI@68525|delta/epsilon subdivisions,2WVV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158343_k127_2089998_16	204669.Acid345_3796	1.745e-173	557.0	COG2006@1|root,COG2006@2|Bacteria,3Y7YQ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SRR25158343_k127_2089998_24	204669.Acid345_3795	4.363e-147	479.0	COG1541@1|root,COG1541@2|Bacteria,3Y7IW@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SRR25158343_k127_2089998_62	234267.Acid_0002	1.205e-93	320.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria	57723|Acidobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158343_k127_2089998_28	1123405.AUMM01000042_gene303	6.267e-137	450.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,26NI0@186821|Sporolactobacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158343_k127_2089998_196	1128427.KB904821_gene2820	1.723e-11	72.0	2E9TG@1|root,333ZH@2|Bacteria,1G9X8@1117|Cyanobacteria,1HDWC@1150|Oscillatoriales	1117|Cyanobacteria	S	Nuclease A inhibitor-like protein	-	-	-	-	-	-	-	-	-	-	-	-	NuiA
SRR25158343_k127_2089998_160	1191523.MROS_2479	2.443e-29	126.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807,DUF4097
SRR25158343_k127_2089998_161	195103.CPF_2844	2.446e-29	134.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,36DNU@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158343_k127_2089998_215	344747.PM8797T_13223	0.0001576	49.0	2CD9R@1|root,2ZRYM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_43	1382359.JIAL01000001_gene1140	2.414e-115	381.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158343_k127_2089998_94	1267533.KB906734_gene4160	1.007e-67	235.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria,2JJ2U@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158343_k127_2089998_192	1118060.CAGZ01000001_gene219	6.818e-13	69.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4CWG7@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158343_k127_2089998_186	648996.Theam_0471	7.969e-15	82.0	COG0594@1|root,COG0594@2|Bacteria,2G4D4@200783|Aquificae	200783|Aquificae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158343_k127_2089998_172	742743.HMPREF9453_02031	4.576e-24	103.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4H5K3@909932|Negativicutes	909932|Negativicutes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158343_k127_2089998_127	1267535.KB906767_gene3477	5.039e-46	188.0	COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria,2JI2B@204432|Acidobacteriia	204432|Acidobacteriia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158343_k127_2089998_180	1121382.JQKG01000010_gene4701	2.212e-16	84.0	COG1847@1|root,COG1847@2|Bacteria,1WJEC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158343_k127_2089998_45	224324.aq_871	9.695e-112	376.0	COG0486@1|root,COG0486@2|Bacteria,2G3TR@200783|Aquificae	200783|Aquificae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158343_k127_2089998_10	240015.ACP_2349	1.013e-201	646.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158343_k127_2089998_63	1267535.KB906767_gene3196	5.107e-93	314.0	COG1192@1|root,COG1192@2|Bacteria,3Y2Y2@57723|Acidobacteria,2JI26@204432|Acidobacteriia	204432|Acidobacteriia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158343_k127_2089998_87	1232410.KI421422_gene2042	4.61e-73	255.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43S4I@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158343_k127_2089998_64	457396.CSBG_00587	1.295e-91	311.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,36DGY@31979|Clostridiaceae	186801|Clostridia	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158343_k127_2089998_201	443144.GM21_3587	1.879e-09	64.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158343_k127_2089998_136	204669.Acid345_2680	5.674e-42	168.0	COG0805@1|root,COG0805@2|Bacteria,3Y3UC@57723|Acidobacteria,2JISU@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158343_k127_2089998_29	234267.Acid_1509	1.983e-135	451.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_158	42256.RradSPS_3078	3.874e-30	123.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158343_k127_2089998_124	237368.SCABRO_01183	3.962e-47	175.0	COG0607@1|root,COG0607@2|Bacteria,2IZ80@203682|Planctomycetes	203682|Planctomycetes	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
SRR25158343_k127_2089998_98	247490.KSU1_C0674	8.104e-66	233.0	COG0730@1|root,COG0730@2|Bacteria,2IY5M@203682|Planctomycetes	203682|Planctomycetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158343_k127_2089998_35	234267.Acid_7272	6.57e-130	429.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
SRR25158343_k127_2089998_153	452637.Oter_1445	5.303e-33	134.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
SRR25158343_k127_2089998_157	639030.JHVA01000001_gene3982	1.731e-30	128.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158343_k127_2089998_120	32049.SYNPCC7002_A1083	2.472e-50	187.0	2DPQC@1|root,332YT@2|Bacteria,1GF5K@1117|Cyanobacteria,1H2V6@1129|Synechococcus	1117|Cyanobacteria	S	Histone deacetylation protein Rxt3	-	-	-	-	-	-	-	-	-	-	-	-	LCCL
SRR25158343_k127_2089998_159	218284.CCDN010000001_gene1198	1.473e-29	123.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus	91061|Bacilli	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	dfrA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
SRR25158343_k127_2089998_143	264462.Bd3477	1.41e-38	151.0	COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria,42Y4E@68525|delta/epsilon subdivisions,2WT9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_137	246197.MXAN_6264	1.125e-41	155.0	COG4539@1|root,COG4539@2|Bacteria,1NXWT@1224|Proteobacteria,4384M@68525|delta/epsilon subdivisions,2X9XD@28221|Deltaproteobacteria,2YVQP@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158343_k127_2089998_40	266117.Rxyl_1675	1.305e-117	394.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4CU2I@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158343_k127_2089998_4	1122603.ATVI01000007_gene1801	4.105e-244	776.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales	135614|Xanthomonadales	S	transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158343_k127_2089998_7	861299.J421_1696	5.372e-227	726.0	COG2866@1|root,COG2866@2|Bacteria,1ZUNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158343_k127_2089998_17	1304872.JAGC01000009_gene46	2.365e-172	565.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,42PKQ@68525|delta/epsilon subdivisions,2WM5Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158343_k127_2089998_99	234267.Acid_6464	6.672e-65	239.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_6464|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_11	1118058.CAGY01000001_gene597	2.465e-189	603.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4D3ID@85005|Actinomycetales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158343_k127_2089998_51	941824.TCEL_01822	1.225e-106	355.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,36DRX@31979|Clostridiaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
SRR25158343_k127_2089998_170	1123371.ATXH01000022_gene961	4e-25	111.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158343_k127_2089998_146	56780.SYN_02013	3.432e-36	144.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,43BPU@68525|delta/epsilon subdivisions,2X712@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
SRR25158343_k127_2089998_93	32057.KB217472_gene7872	5.068e-69	263.0	COG1075@1|root,COG1361@1|root,COG1572@1|root,COG2931@1|root,COG1075@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
SRR25158343_k127_2089998_210	240292.Ava_3537	2.747e-05	55.0	2B5U0@1|root,31YPS@2|Bacteria,1GJSR@1117|Cyanobacteria,1HSGV@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_41	194439.CT0456	7.057e-117	394.0	COG0644@1|root,COG0644@2|Bacteria,1FDTA@1090|Chlorobi	1090|Chlorobi	C	oxidoreductase	-	-	5.5.1.19	ko:K14605	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	-
SRR25158343_k127_2089998_106	1303518.CCALI_01646	2.921e-61	218.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	ComFC	-	-	-	-	-	-	-	-	-	-	-	DZR,Pribosyltran,zinc_ribbon_2
SRR25158343_k127_2089998_85	868864.Dester_1329	5.665e-76	263.0	COG1694@1|root,COG3956@2|Bacteria,2G3T8@200783|Aquificae	200783|Aquificae	S	TIGRFAM MazG family protein	mazG	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
SRR25158343_k127_2089998_194	1144275.COCOR_02400	3.386e-12	74.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2YVZK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR25158343_k127_2089998_89	1313421.JHBV01000031_gene1370	7.939e-72	251.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1INS0@117747|Sphingobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SRR25158343_k127_2089998_114	1227360.C176_08122	2.044e-52	189.0	COG1247@1|root,COG1247@2|Bacteria,1V4AZ@1239|Firmicutes,4HGZ3@91061|Bacilli,26EYT@186818|Planococcaceae	91061|Bacilli	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_2089998_152	315750.BPUM_1137	2.497e-33	136.0	COG1670@1|root,COG1670@2|Bacteria,1V5D0@1239|Firmicutes,4HHID@91061|Bacilli,1ZG49@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158343_k127_2089998_149	318464.IO99_02700	4.362e-35	139.0	COG3981@1|root,COG3981@2|Bacteria,1VBAS@1239|Firmicutes,24IT8@186801|Clostridia,36ISC@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158343_k127_2089998_95	596152.DesU5LDRAFT_3966	1.659e-67	241.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2M8RD@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158343_k127_2089998_91	1123399.AQVE01000011_gene1233	8.202e-70	249.0	2EE8J@1|root,33831@2|Bacteria,1ND96@1224|Proteobacteria,1SED2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_52	313624.NSP_38390	1.701e-106	367.0	COG0661@1|root,COG0661@2|Bacteria,1G1JI@1117|Cyanobacteria,1HIKI@1161|Nostocales	1117|Cyanobacteria	S	pfam abc1	aarF	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158343_k127_2089998_169	204669.Acid345_2015	2.314e-25	116.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158343_k127_2089998_132	1121930.AQXG01000018_gene758	2.621e-44	164.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
SRR25158343_k127_2089998_128	445961.IW15_13605	2.373e-45	166.0	COG0346@1|root,COG0346@2|Bacteria,4NSWT@976|Bacteroidetes,1I4YP@117743|Flavobacteriia,3ZS5V@59732|Chryseobacterium	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158343_k127_2089998_216	1248917.ANFX01000008_gene282	0.0005	48.0	28ZXZ@1|root,2ZMNF@2|Bacteria,1NM5Z@1224|Proteobacteria,2UWBC@28211|Alphaproteobacteria,2K81I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_130	204669.Acid345_4601	1.323e-44	177.0	COG0457@1|root,COG0457@2|Bacteria,3Y7NG@57723|Acidobacteria,2JMP3@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158343_k127_2089998_70	525904.Tter_1363	3.762e-88	303.0	COG0635@1|root,COG0635@2|Bacteria,2NP4Y@2323|unclassified Bacteria	2|Bacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158343_k127_2089998_218	1356852.N008_10130	0.0008169	49.0	COG5661@1|root,COG5661@2|Bacteria,4NGA8@976|Bacteroidetes,47M9V@768503|Cytophagia	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_3	330214.NIDE1392	3.93e-267	842.0	COG0046@1|root,COG0046@2|Bacteria,3J0TJ@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
SRR25158343_k127_2089998_176	1123248.KB893385_gene4832	1.218e-19	100.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1IPR4@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158343_k127_2089998_134	1191523.MROS_1419	2.779e-43	165.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158343_k127_2089998_47	525904.Tter_2338	7.347e-109	365.0	COG2239@1|root,COG2239@2|Bacteria,2NP79@2323|unclassified Bacteria	2|Bacteria	P	MgtE intracellular N domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR25158343_k127_2089998_147	631362.Thi970DRAFT_00139	1.262e-35	147.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1WZ62@135613|Chromatiales	135613|Chromatiales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
SRR25158343_k127_2089998_202	390989.JOEG01000005_gene2065	5.518e-09	64.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4DD6M@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158343_k127_2089998_36	1089548.KI783301_gene1764	2.347e-129	422.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3WEU6@539002|Bacillales incertae sedis	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_2089998_110	1122925.KB895399_gene234	7.893e-56	207.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158343_k127_2089998_97	1121403.AUCV01000014_gene4608	5.822e-66	253.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2MHUB@213118|Desulfobacterales	28221|Deltaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SRR25158343_k127_2089998_0	1278073.MYSTI_05900	0.0	1403.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158343_k127_2089998_75	204669.Acid345_3013	6.067e-83	286.0	COG0395@1|root,COG0395@2|Bacteria,3Y7HR@57723|Acidobacteria	57723|Acidobacteria	G	Inward rectifier potassium channel	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
SRR25158343_k127_2089998_34	485913.Krac_11844	2.198e-132	441.0	COG0477@1|root,COG0477@2|Bacteria,2G5J9@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_2089998_105	29306.JOBE01000002_gene2839	1.212e-62	222.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158343_k127_2089998_217	1286632.P278_09370	0.0005	48.0	COG3187@1|root,COG3650@1|root,COG3187@2|Bacteria,COG3650@2|Bacteria,4NN1R@976|Bacteroidetes,1I1BF@117743|Flavobacteriia	976|Bacteroidetes	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META,NlpE
SRR25158343_k127_2089998_131	10228.TriadP58018	2.068e-44	166.0	COG0456@1|root,KOG3139@2759|Eukaryota,3A5U0@33154|Opisthokonta	33154|Opisthokonta	S	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_2089998_14	886293.Sinac_0940	3.387e-184	591.0	COG2234@1|root,COG2234@2|Bacteria,2IZHS@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158343_k127_2089998_168	1403819.BATR01000049_gene1425	1.464e-25	113.0	COG3963@1|root,COG3963@2|Bacteria,46WXJ@74201|Verrucomicrobia,2IW1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158343_k127_2089998_2	1267535.KB906767_gene2433	8.942e-298	935.0	COG0550@1|root,COG0550@2|Bacteria,3Y343@57723|Acidobacteria,2JHPW@204432|Acidobacteriia	204432|Acidobacteriia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158343_k127_2089998_59	639030.JHVA01000001_gene3564	4.495e-96	327.0	COG0758@1|root,COG0758@2|Bacteria,3Y42M@57723|Acidobacteria,2JI6N@204432|Acidobacteriia	204432|Acidobacteriia	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158343_k127_2089998_198	338963.Pcar_1000	9.804e-11	72.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,43SGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158343_k127_2089998_103	204669.Acid345_0278	1.248e-63	228.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
SRR25158343_k127_2089998_86	1298863.AUEP01000001_gene1082	4.268e-74	259.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4DPP7@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158343_k127_2089998_111	289376.THEYE_A0571	1.958e-53	202.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,3J0VG@40117|Nitrospirae	40117|Nitrospirae	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158343_k127_2089998_90	1304888.ATWF01000001_gene1131	3.374e-70	251.0	COG1077@1|root,COG1077@2|Bacteria,2GEVU@200930|Deferribacteres	200930|Deferribacteres	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158343_k127_2089998_83	109871.XP_006679093.1	2.433e-76	278.0	COG2114@1|root,KOG1023@2759|Eukaryota,3AIAN@33154|Opisthokonta,3PB75@4751|Fungi	4751|Fungi	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,Guanylate_cyc
SRR25158343_k127_2089998_38	1121459.AQXE01000009_gene554	7.076e-125	411.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158343_k127_2089998_55	391625.PPSIR1_26006	5.248e-103	365.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,434NC@68525|delta/epsilon subdivisions,2WYZN@28221|Deltaproteobacteria,2Z10G@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158343_k127_2089998_88	1121104.AQXH01000002_gene666	8.693e-73	256.0	28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,1IZ2P@117747|Sphingobacteriia	976|Bacteroidetes	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
SRR25158343_k127_2089998_76	886293.Sinac_5558	1.38e-82	287.0	COG0624@1|root,COG0624@2|Bacteria,2IZ39@203682|Planctomycetes	203682|Planctomycetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158343_k127_2089998_71	251221.35210700	3.29e-87	297.0	COG0708@1|root,COG0708@2|Bacteria,1G29X@1117|Cyanobacteria	1117|Cyanobacteria	L	Exodeoxyribonuclease iii	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158343_k127_2089998_21	1173021.ALWA01000020_gene220	1.041e-152	492.0	COG0436@1|root,COG0436@2|Bacteria,1G202@1117|Cyanobacteria	1117|Cyanobacteria	E	Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_2089998_167	1198114.AciX9_0361	1.867e-26	121.0	COG0265@1|root,COG0265@2|Bacteria,3Y4AJ@57723|Acidobacteria,2JJ4W@204432|Acidobacteriia	204432|Acidobacteriia	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
SRR25158343_k127_2089998_42	595460.RRSWK_04856	2.412e-116	384.0	28M67@1|root,2ZAJW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_22	903818.KI912268_gene729	1.407e-151	495.0	COG1232@1|root,COG1232@2|Bacteria,3Y3KX@57723|Acidobacteria	57723|Acidobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158343_k127_2089998_123	443143.GM18_1466	1.835e-47	173.0	COG0614@1|root,COG0614@2|Bacteria,1MZ6W@1224|Proteobacteria	1224|Proteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158343_k127_2089998_15	1242864.D187_003660	2.823e-182	584.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42N8N@68525|delta/epsilon subdivisions,2WKR3@28221|Deltaproteobacteria,2YUA0@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158343_k127_2089998_181	1192034.CAP_1496	2.821e-16	80.0	2DI1Z@1|root,301RV@2|Bacteria,1NM7Q@1224|Proteobacteria,433HJ@68525|delta/epsilon subdivisions,2WXZG@28221|Deltaproteobacteria,2Z1QD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158343_k127_2089998_31	1121920.AUAU01000009_gene1851	1.631e-134	451.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158343_k127_2089998_155	204669.Acid345_0106	3.932e-31	126.0	COG1586@1|root,COG1586@2|Bacteria,3Y8GM@57723|Acidobacteria	57723|Acidobacteria	E	S-adenosylmethionine decarboxylase	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
SRR25158343_k127_2089998_139	216594.MMAR_0242	4.78e-41	164.0	COG0657@1|root,COG0823@1|root,COG0657@2|Bacteria,COG0823@2|Bacteria,2I40M@201174|Actinobacteria,233DD@1762|Mycobacteriaceae	201174|Actinobacteria	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE
SRR25158343_k127_2089998_116	1123278.KB893563_gene4528	4.271e-51	186.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PPC@768503|Cytophagia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158343_k127_2089998_102	880073.Calab_0822	3.733e-64	226.0	COG1435@1|root,COG1435@2|Bacteria,2NP88@2323|unclassified Bacteria	2|Bacteria	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
SRR25158343_k127_2089998_171	204669.Acid345_3993	4.081e-25	118.0	COG2304@1|root,COG2304@2|Bacteria,3Y44P@57723|Acidobacteria,2JIT1@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_2089998_58	886293.Sinac_7192	7.3e-98	327.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158343_k127_2089998_207	1173020.Cha6605_1439	5.937e-08	54.0	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Plasmid stabilisation system protein	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158343_k127_2089998_206	762903.Pedsa_3487	5.577e-08	54.0	2EC7X@1|root,3366F@2|Bacteria,4NMV1@976|Bacteroidetes,1IYXF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_199	1453498.LG45_09845	4.082e-10	66.0	2DQ1A@1|root,2ZZUS@2|Bacteria,4PG7T@976|Bacteroidetes,1IDY2@117743|Flavobacteriia,2NZFZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_212	1337936.IJ00_04720	4e-05	56.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,1FZVW@1117|Cyanobacteria,1HMS2@1161|Nostocales	1117|Cyanobacteria	T	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
SRR25158343_k127_2089998_191	469618.FVAG_02649	2.791e-13	83.0	COG1729@1|root,COG1729@2|Bacteria,37AC6@32066|Fusobacteria	32066|Fusobacteria	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
SRR25158343_k127_2089998_142	579137.Metvu_0990	2.913e-39	168.0	COG0515@1|root,arCOG03682@2157|Archaea,2XWZP@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_2089998_18	234267.Acid_6644	4.653e-169	552.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158343_k127_2089998_48	517418.Ctha_1875	1.329e-108	361.0	COG0009@1|root,COG0009@2|Bacteria,1FDI3@1090|Chlorobi	1090|Chlorobi	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158343_k127_2089998_53	272134.KB731324_gene4758	2.16e-106	377.0	COG0419@1|root,COG0419@2|Bacteria,1G281@1117|Cyanobacteria,1HA31@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM RecF RecN SMC N terminal domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_21,AAA_23,SMC_N
SRR25158343_k127_2089998_115	378806.STAUR_7858	4.116e-51	188.0	COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,42SK8@68525|delta/epsilon subdivisions,2WPU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158343_k127_2089998_175	312309.VF_1936	8.993e-22	100.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XT8K@135623|Vibrionales	135623|Vibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158343_k127_2089998_65	945713.IALB_2314	2.708e-91	326.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158343_k127_2089998_138	1410653.JHVC01000009_gene2830	1.668e-41	165.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,36FBU@31979|Clostridiaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158343_k127_2089998_72	1069080.KB913028_gene1617	1.269e-86	295.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H1WW@909932|Negativicutes	909932|Negativicutes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158343_k127_2089998_211	533240.CRC_02550	2.968e-05	58.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria,1HM3X@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
SRR25158343_k127_2089998_174	717231.Flexsi_0998	1.455e-22	106.0	COG1579@1|root,COG1579@2|Bacteria,2GFHX@200930|Deferribacteres	200930|Deferribacteres	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158343_k127_2089998_33	266117.Rxyl_3166	5.983e-133	444.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
SRR25158343_k127_2089998_23	1267535.KB906767_gene758	1.823e-148	501.0	COG1530@1|root,COG1530@2|Bacteria,3Y40K@57723|Acidobacteria,2JHQU@204432|Acidobacteriia	204432|Acidobacteriia	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR25158343_k127_2089998_208	682795.AciX8_0365	2.572e-07	61.0	2A6XZ@1|root,30VSX@2|Bacteria,3Y4RH@57723|Acidobacteria,2JJCB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2089998_27	443254.Marpi_1745	3.954e-140	472.0	COG0542@1|root,COG0542@2|Bacteria,2GC73@200918|Thermotogae	200918|Thermotogae	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158343_k127_2089998_104	1123399.AQVE01000026_gene3025	6.883e-63	223.0	COG4636@1|root,COG4636@2|Bacteria,1RKNN@1224|Proteobacteria,1S8PQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158343_k127_2089998_173	717605.Theco_2404	1.937e-23	108.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158343_k127_2089998_193	929712.KI912613_gene712	8.042e-13	78.0	COG1376@1|root,COG1376@2|Bacteria,2HSK1@201174|Actinobacteria,4CS2R@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158343_k127_2126608_1	243233.MCA0142	1.38e-56	205.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158343_k127_2126608_0	1121918.ARWE01000001_gene1736	3.624e-168	537.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42PR5@68525|delta/epsilon subdivisions,2WMGT@28221|Deltaproteobacteria,43W24@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158343_k127_2150355_0	335543.Sfum_1860	4.044e-85	299.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_2150355_1	489825.LYNGBM3L_21200	4.567e-29	118.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_2189261_43	69395.JQLZ01000002_gene942	1.023e-20	91.0	COG3717@1|root,COG3717@2|Bacteria,1MU9D@1224|Proteobacteria,2TSU5@28211|Alphaproteobacteria,2KHY1@204458|Caulobacterales	204458|Caulobacterales	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158343_k127_2189261_8	1267533.KB906733_gene3250	4.44e-197	632.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JHXZ@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158343_k127_2189261_9	1267534.KB906754_gene3614	8.817e-190	618.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria,2JIH1@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_2189261_5	234267.Acid_2679	1.831e-244	778.0	COG1472@1|root,COG1472@2|Bacteria,3Y3QE@57723|Acidobacteria	57723|Acidobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158343_k127_2189261_1	1382359.JIAL01000001_gene1503	5.904e-255	827.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158343_k127_2189261_22	1267534.KB906754_gene2891	1.468e-81	299.0	COG0457@1|root,COG0457@2|Bacteria,3Y74E@57723|Acidobacteria,2JK7F@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158343_k127_2189261_2	1382359.JIAL01000001_gene1409	3.551e-253	793.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JKYK@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158343_k127_2189261_12	649638.Trad_2531	3.499e-142	457.0	COG0667@1|root,COG0667@2|Bacteria,1WKZ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_2189261_15	1267534.KB906755_gene4156	1.192e-134	437.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Z2@57723|Acidobacteria,2JMN3@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158343_k127_2189261_40	204669.Acid345_1693	2.584e-31	128.0	2E81U@1|root,332FW@2|Bacteria,3Y5IC@57723|Acidobacteria,2JJWT@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2189261_4	945713.IALB_2579	7.162e-251	797.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	bglX	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158343_k127_2189261_33	714943.Mucpa_1912	1.026e-45	181.0	COG2730@1|root,COG2730@2|Bacteria,4NJFV@976|Bacteroidetes,1IXI3@117747|Sphingobacteriia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	celC	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SRR25158343_k127_2189261_7	215803.DB30_3103	4.204e-206	666.0	COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,42YD5@68525|delta/epsilon subdivisions,2X313@28221|Deltaproteobacteria,2YTXH@29|Myxococcales	28221|Deltaproteobacteria	G	Putative carbohydrate binding domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
SRR25158343_k127_2189261_27	1121382.JQKG01000003_gene4250	7.06e-65	235.0	COG1940@1|root,COG1940@2|Bacteria,1WI42@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158343_k127_2189261_16	378806.STAUR_5260	4.267e-126	416.0	COG2706@1|root,COG2706@2|Bacteria,1MUKZ@1224|Proteobacteria,4394D@68525|delta/epsilon subdivisions,2X4AE@28221|Deltaproteobacteria,2YYM5@29|Myxococcales	28221|Deltaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
SRR25158343_k127_2189261_19	861299.J421_5627	1.626e-99	331.0	COG2273@1|root,COG2273@2|Bacteria,1ZUUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRR25158343_k127_2189261_3	1408473.JHXO01000001_gene2217	2.861e-251	800.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FN2H@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	csxA_2	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_N
SRR25158343_k127_2189261_29	639030.JHVA01000001_gene3673	1.653e-59	221.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria,2JIYY@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158343_k127_2189261_23	1158608.I583_00248	7.59e-79	269.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HCWT@91061|Bacilli,4AZIE@81852|Enterococcaceae	91061|Bacilli	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_2189261_28	223184.AS25_07540	9.938e-65	237.0	COG0577@1|root,COG0577@2|Bacteria,2HSU1@201174|Actinobacteria,1W7RQ@1268|Micrococcaceae	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_2189261_36	314230.DSM3645_05894	1.719e-37	143.0	COG0393@1|root,COG0393@2|Bacteria,2J0RP@203682|Planctomycetes	203682|Planctomycetes	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158343_k127_2189261_34	32042.PstZobell_00417	2.04e-41	157.0	COG0454@1|root,COG0456@2|Bacteria,1NDIX@1224|Proteobacteria,1S9JW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_2189261_25	1122604.JONR01000033_gene34	6.909e-70	245.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158343_k127_2189261_32	1254432.SCE1572_26545	8.292e-50	191.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158343_k127_2189261_0	1279009.ADICEAN_02099	0.0	1155.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47U1U@768503|Cytophagia	976|Bacteroidetes	E	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4,Peptidase_M1
SRR25158343_k127_2189261_14	865937.Gilli_3266	3.671e-136	438.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1HXEB@117743|Flavobacteriia,2P5VI@244698|Gillisia	976|Bacteroidetes	V	COGs COG1131 ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158343_k127_2189261_39	1121930.AQXG01000001_gene1398	4.272e-34	145.0	2DPWS@1|root,333QK@2|Bacteria	2|Bacteria	-	-	-	-	4.2.1.131	ko:K09844	ko00906,ko01100,map00906,map01100	-	R07516,R07519,R07522,R07528,R07532,R07536,R07539,R07543,R09790	RC00966	ko00000,ko00001,ko01000	-	-	-	-
SRR25158343_k127_2189261_47	179408.Osc7112_5297	2.329e-05	52.0	2E789@1|root,331RY@2|Bacteria,1G9HM@1117|Cyanobacteria,1HC8E@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2189261_13	1380350.JIAP01000005_gene2945	1.157e-139	460.0	COG0477@1|root,COG0477@2|Bacteria,1RGPN@1224|Proteobacteria,2TQKW@28211|Alphaproteobacteria,43RR7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRR25158343_k127_2189261_24	1303518.CCALI_00314	7.812e-73	265.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158343_k127_2189261_11	484770.UFO1_1464	4.406e-162	530.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4H723@909932|Negativicutes	909932|Negativicutes	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158343_k127_2189261_48	13333.ERN05462	0.0008566	51.0	KOG2293@1|root,KOG2293@2759|Eukaryota,37MPN@33090|Viridiplantae,3GBDD@35493|Streptophyta	35493|Streptophyta	KT	domain-containing protein	-	GO:0000123,GO:0000228,GO:0000785,GO:0000790,GO:0002151,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005783,GO:0005844,GO:0006325,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010521,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0012505,GO:0016043,GO:0016569,GO:0016570,GO:0016573,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019538,GO:0030234,GO:0030425,GO:0031011,GO:0031248,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033202,GO:0034046,GO:0034708,GO:0035097,GO:0036211,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043086,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043543,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044463,GO:0044464,GO:0044665,GO:0045934,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051338,GO:0051348,GO:0051972,GO:0051974,GO:0060255,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070603,GO:0070717,GO:0071339,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097346,GO:0097447,GO:0097458,GO:0098772,GO:0120025,GO:0120038,GO:1900180,GO:1900182,GO:1901363,GO:1901564,GO:1902493,GO:1902494,GO:1903827,GO:1903829,GO:1904356,GO:1904357,GO:1904749,GO:1904751,GO:1904949,GO:1990234,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251	-	ko:K11674	ko05168,map05168	-	-	-	ko00000,ko00001,ko03036	-	-	-	FHA,MCRS_N
SRR25158343_k127_2189261_42	1397693.KK211187_gene1173	3.294e-27	127.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3WEHU@539002|Bacillales incertae sedis	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158343_k127_2189261_46	469378.Ccur_03340	6.816e-08	64.0	COG1716@1|root,COG1716@2|Bacteria,2HUFE@201174|Actinobacteria,4CUEU@84998|Coriobacteriia	84998|Coriobacteriia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158343_k127_2189261_37	272562.CA_C0506	2.548e-37	160.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,36EMG@31979|Clostridiaceae	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158343_k127_2189261_38	306537.jk0040	8.416e-35	151.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,22KAF@1653|Corynebacteriaceae	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158343_k127_2189261_35	929712.KI912613_gene1134	7.382e-40	167.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158343_k127_2189261_17	945713.IALB_0548	1.262e-124	412.0	COG0213@1|root,COG0213@2|Bacteria	2|Bacteria	F	phosphorylase activity	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158343_k127_2189261_21	469617.FUAG_02984	2.712e-95	325.0	COG2304@1|root,COG2304@2|Bacteria,37BRZ@32066|Fusobacteria	32066|Fusobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_2189261_18	264462.Bd0445	1.921e-101	341.0	COG1744@1|root,COG1744@2|Bacteria,1NGHH@1224|Proteobacteria,42RBQ@68525|delta/epsilon subdivisions,2MTH8@213481|Bdellovibrionales,2WN1W@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	PFAM Basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158343_k127_2189261_10	670487.Ocepr_0826	1.506e-170	548.0	COG3845@1|root,COG3845@2|Bacteria,1WIKU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158343_k127_2189261_45	1122613.ATUP01000001_gene1189	3.51e-08	61.0	COG3476@1|root,COG3476@2|Bacteria,1Q1NU@1224|Proteobacteria,2V9CE@28211|Alphaproteobacteria,440GM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRR25158343_k127_2189261_20	1123325.JHUV01000009_gene326	5.639e-96	327.0	COG0436@1|root,COG0436@2|Bacteria,2G3VY@200783|Aquificae	200783|Aquificae	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_2189261_31	218284.CCDN010000002_gene2535	8.209e-50	180.0	COG0346@1|root,COG0346@2|Bacteria,1VAEF@1239|Firmicutes,4HGTX@91061|Bacilli,1ZIBX@1386|Bacillus	91061|Bacilli	E	Glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158343_k127_2189261_30	1267533.KB906733_gene3430	5.546e-54	194.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158343_k127_2189261_41	1047013.AQSP01000139_gene2414	5.27e-28	123.0	COG0457@1|root,COG0457@2|Bacteria,2NRWN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2189261_26	502025.Hoch_3628	3.099e-67	237.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2Z36A@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158343_k127_2189261_6	404589.Anae109_1213	7.652e-220	693.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158343_k127_2189261_44	502025.Hoch_3248	3.01e-10	62.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158343_k127_2210497_26	1340493.JNIF01000003_gene3205	1e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria	57723|Acidobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_2210497_12	1267535.KB906767_gene2705	1.761e-52	186.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158343_k127_2210497_6	748449.Halha_0189	1.878e-69	241.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WAJF@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158343_k127_2210497_10	1267535.KB906767_gene2703	1.578e-57	207.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria,2JIZE@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158343_k127_2210497_25	204669.Acid345_1228	1.272e-19	92.0	COG0089@1|root,COG0089@2|Bacteria,3Y58W@57723|Acidobacteria,2JJR2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158343_k127_2210497_1	1340493.JNIF01000003_gene3210	2.724e-121	394.0	COG0090@1|root,COG0090@2|Bacteria,3Y3DH@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158343_k127_2210497_19	289376.THEYE_A1442	1.276e-34	134.0	COG0185@1|root,COG0185@2|Bacteria,3J0MU@40117|Nitrospirae	40117|Nitrospirae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158343_k127_2210497_23	929562.Emtol_0510	7.801e-22	104.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,47QFH@768503|Cytophagia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158343_k127_2210497_2	1340493.JNIF01000003_gene3213	8.741e-87	293.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158343_k127_2210497_7	1540257.JQMW01000011_gene2063	3.993e-64	222.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,36E4K@31979|Clostridiaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158343_k127_2210497_29	523794.Lebu_0247	5.057e-05	48.0	COG0255@1|root,COG0255@2|Bacteria,37BA7@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158343_k127_2210497_24	338963.Pcar_0710	9.083e-22	101.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,43VE7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158343_k127_2210497_15	1163389.OOM_0231	1.007e-46	170.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,460HS@72273|Thiotrichales	72273|Thiotrichales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158343_k127_2210497_22	1220551.SCHR_06105	2.217e-25	111.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,4GZ3Q@90964|Staphylococcaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158343_k127_2210497_3	370438.PTH_0332	7.409e-84	282.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158343_k127_2210497_21	863239.AFIZ01000013_gene1223	3.824e-33	130.0	COG0199@1|root,COG0199@2|Bacteria,2IKN9@201174|Actinobacteria,22NID@1653|Corynebacteriaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158343_k127_2210497_16	1340493.JNIF01000003_gene3221	9.268e-46	168.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158343_k127_2210497_11	1267533.KB906735_gene5115	2.661e-55	199.0	COG0097@1|root,COG0097@2|Bacteria,3Y496@57723|Acidobacteria,2JJ4H@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158343_k127_2210497_18	1340493.JNIF01000003_gene3223	3.565e-40	152.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria	57723|Acidobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158343_k127_2210497_8	398512.JQKC01000042_gene4178	2.03e-61	215.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158343_k127_2210497_28	278963.ATWD01000001_gene1822	3.665e-13	72.0	COG1841@1|root,COG1841@2|Bacteria,3Y5I2@57723|Acidobacteria,2JJZB@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158343_k127_2210497_17	858215.Thexy_0353	2.237e-43	163.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158343_k127_2210497_0	278963.ATWD01000001_gene1820	7.24e-146	476.0	COG0201@1|root,COG0201@2|Bacteria,3Y38D@57723|Acidobacteria,2JISZ@204432|Acidobacteriia	204432|Acidobacteriia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158343_k127_2210497_9	1123371.ATXH01000034_gene775	9.118e-61	216.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158343_k127_2210497_4	1120985.AUMI01000006_gene2203	1.084e-82	283.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158343_k127_2210497_20	401053.AciPR4_3213	5.274e-34	132.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria,2JJUQ@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158343_k127_2210497_27	1367491.BN865_05530c	6.419e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2YQQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158343_k127_2210497_13	697303.Thewi_2230	1.752e-47	173.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158343_k127_2210497_14	1267535.KB906767_gene2680	2.011e-47	173.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158343_k127_2210497_5	278963.ATWD01000001_gene1813	2.164e-72	250.0	COG0522@1|root,COG0522@2|Bacteria,3Y2I1@57723|Acidobacteria,2JHR6@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158343_k127_222153_0	234267.Acid_5431	3.215e-129	437.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_222153_1	234267.Acid_5431	2.463e-66	242.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_2231067_0	1336803.PHEL49_0023	5.034e-13	71.0	2CAWQ@1|root,33AP4@2|Bacteria,4NXQ3@976|Bacteroidetes,1I6HG@117743|Flavobacteriia,3VXE3@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_2231067_1	1054213.HMPREF9946_05337	8.005e-09	67.0	COG5655@1|root,COG5655@2|Bacteria,1N22J@1224|Proteobacteria,2UGBX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_1
SRR25158343_k127_246708_195	204669.Acid345_0395	1.744e-65	239.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria,2JP02@204432|Acidobacteriia	204432|Acidobacteriia	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_246708_410	74547.PMT_1811	7.747e-09	67.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_246708_317	502025.Hoch_3506	6.331e-33	136.0	COG0406@1|root,COG0406@2|Bacteria,1QNKV@1224|Proteobacteria,435FE@68525|delta/epsilon subdivisions,2WZSY@28221|Deltaproteobacteria,2Z2PF@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158343_k127_246708_80	240015.ACP_2651	1.599e-143	463.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria,2JHYH@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158343_k127_246708_181	1340493.JNIF01000004_gene264	3.778e-70	252.0	COG3872@1|root,COG3872@2|Bacteria,3Y66K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158343_k127_246708_245	864069.MicloDRAFT_00046540	1.975e-48	179.0	COG2323@1|root,COG2323@2|Bacteria,1PKVB@1224|Proteobacteria,2UZH7@28211|Alphaproteobacteria,1JUD7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158343_k127_246708_336	395493.BegalDRAFT_1852	1.448e-28	116.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,461AF@72273|Thiotrichales	72273|Thiotrichales	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158343_k127_246708_383	267747.PPA2344	2.402e-17	90.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4DR7I@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158343_k127_246708_201	1158318.ATXC01000001_gene1019	1.922e-62	222.0	COG0325@1|root,COG0325@2|Bacteria,2G4IZ@200783|Aquificae	200783|Aquificae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158343_k127_246708_427	314287.GB2207_08106	9.782e-07	58.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158343_k127_246708_368	517418.Ctha_0036	1.675e-20	94.0	COG1872@1|root,COG1872@2|Bacteria,1FE84@1090|Chlorobi	1090|Chlorobi	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158343_k127_246708_130	204669.Acid345_2125	8.834e-98	325.0	COG0217@1|root,COG0217@2|Bacteria,3Y2UW@57723|Acidobacteria,2JIJW@204432|Acidobacteriia	204432|Acidobacteriia	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158343_k127_246708_254	643648.Slip_0741	4.402e-46	171.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,42JYC@68298|Syntrophomonadaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158343_k127_246708_131	1123302.KB904156_gene1496	6.803e-95	320.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,4HC38@91061|Bacilli	91061|Bacilli	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158343_k127_246708_267	443143.GM18_1701	1.208e-42	166.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158343_k127_246708_256	1162668.LFE_1933	1.043e-45	174.0	COG0571@1|root,COG0571@2|Bacteria,3J119@40117|Nitrospirae	40117|Nitrospirae	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	-	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158343_k127_246708_95	221288.JH992901_gene2502	4.158e-125	413.0	COG1819@1|root,COG1819@2|Bacteria,1G3IM@1117|Cyanobacteria,1JIXF@1189|Stigonemataceae	1117|Cyanobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
SRR25158343_k127_246708_341	1294265.JCM21738_4707	8.903e-28	127.0	COG3206@1|root,COG3206@2|Bacteria,1V8AX@1239|Firmicutes,4HCT2@91061|Bacilli,1ZDP1@1386|Bacillus	91061|Bacilli	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158343_k127_246708_232	765912.Thimo_3399	1.07e-52	192.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1WYE4@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158343_k127_246708_308	1123508.JH636448_gene7636	5.066e-34	148.0	COG0515@1|root,COG0515@2|Bacteria,2J2VN@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_246708_210	1267534.KB906754_gene2807	9.831e-59	211.0	COG2128@1|root,COG2128@2|Bacteria,3Y7Z1@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158343_k127_246708_89	706587.Desti_0351	6.357e-130	430.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_246708_186	671143.DAMO_2838	4.518e-69	254.0	COG4191@1|root,COG4191@2|Bacteria,2NQ9P@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158343_k127_246708_248	204669.Acid345_3450	4.87e-48	191.0	COG0768@1|root,COG0768@2|Bacteria,3Y3EP@57723|Acidobacteria,2JI45@204432|Acidobacteriia	204432|Acidobacteriia	M	penicillin-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
SRR25158343_k127_246708_65	661478.OP10G_1859	4.48e-155	512.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158343_k127_246708_350	870187.Thini_1410	5.965e-25	115.0	COG4461@1|root,COG4461@2|Bacteria,1NH4M@1224|Proteobacteria	1224|Proteobacteria	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_178	861299.J421_3685	3.189e-72	248.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158343_k127_246708_176	373903.Hore_18890	1.729e-72	261.0	COG0859@1|root,COG1519@1|root,COG0859@2|Bacteria,COG1519@2|Bacteria,1TT7Z@1239|Firmicutes,24KS2@186801|Clostridia,3WCB0@53433|Halanaerobiales	186801|Clostridia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glyco_transf_9,Glycos_transf_N
SRR25158343_k127_246708_196	926692.AZYG01000040_gene1541	5.575e-65	235.0	COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,24HYU@186801|Clostridia,3WAME@53433|Halanaerobiales	186801|Clostridia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158343_k127_246708_255	502025.Hoch_3876	4.907e-46	185.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria,2YXDF@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
SRR25158343_k127_246708_421	1340493.JNIF01000003_gene3631	3.102e-07	57.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158343_k127_246708_299	1340493.JNIF01000003_gene3632	2.917e-35	146.0	COG0356@1|root,COG0356@2|Bacteria,3Y4CM@57723|Acidobacteria	57723|Acidobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158343_k127_246708_423	269799.Gmet_3358	4.498e-07	57.0	2BF8R@1|root,3291I@2|Bacteria,1QN8M@1224|Proteobacteria,437DE@68525|delta/epsilon subdivisions,2X2JG@28221|Deltaproteobacteria,43VQ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ATP synthase I chain	atpI	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
SRR25158343_k127_246708_449	1449049.JONW01000005_gene1440	0.000222	48.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UH8M@28211|Alphaproteobacteria,2KHA6@204458|Caulobacterales	204458|Caulobacterales	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158343_k127_246708_182	1235803.C825_01776	4.057e-70	251.0	COG0535@1|root,COG0535@2|Bacteria,4PA9R@976|Bacteroidetes,2FWDR@200643|Bacteroidia	976|Bacteroidetes	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
SRR25158343_k127_246708_241	743836.AYNA01000104_gene2059	8.327e-50	193.0	COG1215@1|root,COG1215@2|Bacteria,1R8UT@1224|Proteobacteria,2TVQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
SRR25158343_k127_246708_369	977880.RALTA_B0262	2.308e-20	99.0	COG1637@1|root,COG1637@2|Bacteria,1NA4I@1224|Proteobacteria,2VZ7F@28216|Betaproteobacteria,1K60E@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Endonuclease NucS	-	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158343_k127_246708_47	382464.ABSI01000021_gene413	1.446e-176	560.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158343_k127_246708_237	1123376.AUIU01000014_gene612	8.257e-51	192.0	COG0135@1|root,COG0135@2|Bacteria,3J0SA@40117|Nitrospirae	40117|Nitrospirae	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158343_k127_246708_219	1158318.ATXC01000001_gene1455	4.788e-57	208.0	COG0134@1|root,COG0134@2|Bacteria,2G3YD@200783|Aquificae	200783|Aquificae	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158343_k127_246708_156	1449126.JQKL01000014_gene2976	2.255e-84	291.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,267KV@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158343_k127_246708_164	1382306.JNIM01000001_gene2647	1.18e-78	267.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi	200795|Chloroflexi	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158343_k127_246708_90	1131269.AQVV01000007_gene1011	1.019e-128	427.0	COG0147@1|root,COG0147@2|Bacteria	2|Bacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158343_k127_246708_163	109760.SPPG_06999T0	8.255e-79	273.0	COG1028@1|root,KOG0725@2759|Eukaryota,3905U@33154|Opisthokonta,3NVVN@4751|Fungi	4751|Fungi	Q	Sporulation protein SPS19	SPS19	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0007049,GO:0008150,GO:0008152,GO:0008670,GO:0009056,GO:0009062,GO:0009653,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0031907,GO:0031974,GO:0032502,GO:0032505,GO:0032787,GO:0034293,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046395,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:1901575,GO:1903046	1.3.1.34	ko:K13237	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158343_k127_246708_262	1340493.JNIF01000003_gene4280	1.811e-44	170.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria	57723|Acidobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_175	1232410.KI421424_gene1720	7.238e-73	261.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43S42@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	HrcA protein C terminal domain	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158343_k127_246708_353	646529.Desaci_4012	8.04e-24	111.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158343_k127_246708_17	1379281.AVAG01000028_gene141	8.013e-243	763.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2M9A5@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158343_k127_246708_96	1232410.KI421424_gene1723	5.073e-125	410.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158343_k127_246708_217	1120999.JONM01000004_gene3718	1.357e-57	205.0	COG4899@1|root,COG4899@2|Bacteria,1N9UQ@1224|Proteobacteria,2VWTJ@28216|Betaproteobacteria,2KS9D@206351|Neisseriales	206351|Neisseriales	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
SRR25158343_k127_246708_316	1267535.KB906767_gene2672	6.268e-33	132.0	COG1610@1|root,COG1610@2|Bacteria,3Y4VF@57723|Acidobacteria,2JJJH@204432|Acidobacteriia	204432|Acidobacteriia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158343_k127_246708_358	926566.Terro_4379	1.016e-22	100.0	COG0776@1|root,COG0776@2|Bacteria,3Y50P@57723|Acidobacteria,2JJJ5@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158343_k127_246708_229	1123376.AUIU01000013_gene1890	6.871e-54	195.0	COG0127@1|root,COG0127@2|Bacteria,3J0ST@40117|Nitrospirae	40117|Nitrospirae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158343_k127_246708_40	404380.Gbem_3035	1.74e-191	621.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
SRR25158343_k127_246708_300	246197.MXAN_4169	5.123e-35	141.0	COG1716@1|root,COG1716@2|Bacteria,1N47K@1224|Proteobacteria,434WB@68525|delta/epsilon subdivisions,2WZ7A@28221|Deltaproteobacteria,2Z1HC@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
SRR25158343_k127_246708_377	864051.BurJ1DRAFT_1088	5.592e-18	89.0	296WU@1|root,2ZU5K@2|Bacteria,1PBR9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_344	156578.ATW7_01792	1.258e-26	126.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1R9SB@1224|Proteobacteria,1RYBD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
SRR25158343_k127_246708_188	63737.Npun_R1097	1.221e-68	236.0	COG4104@1|root,COG4104@2|Bacteria,1G6FA@1117|Cyanobacteria	1117|Cyanobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
SRR25158343_k127_246708_343	1079986.JH164879_gene2144	5.049e-27	115.0	COG3631@1|root,COG3631@2|Bacteria,2GX6I@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158343_k127_246708_393	861299.J421_6251	2.858e-14	81.0	2EE31@1|root,337XM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_78	234267.Acid_7916	5.745e-145	490.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	234267.Acid_7916|-	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_246708_211	234267.Acid_7677	9.976e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_246708_281	1124780.ANNU01000018_gene1662	6.482e-39	150.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158343_k127_246708_138	163908.KB235896_gene4436	3.932e-93	315.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1HJXK@1161|Nostocales	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
SRR25158343_k127_246708_174	177439.DP0755	1.622e-73	268.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_246708_27	1379698.RBG1_1C00001G0471	5.413e-215	678.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158343_k127_246708_69	861299.J421_1737	1.127e-151	492.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
SRR25158343_k127_246708_261	1267533.KB906734_gene4339	4.029e-45	171.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158343_k127_246708_15	714943.Mucpa_3534	1.121e-260	822.0	COG0514@1|root,COG0514@2|Bacteria,4NG10@976|Bacteroidetes,1IQU0@117747|Sphingobacteriia	976|Bacteroidetes	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158343_k127_246708_66	1382359.JIAL01000001_gene754	6.434e-155	499.0	COG0686@1|root,COG0686@2|Bacteria,3Y3Y9@57723|Acidobacteria,2JI1M@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158343_k127_246708_370	395493.BegalDRAFT_0545	4.41e-20	94.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158343_k127_246708_391	306281.AJLK01000161_gene226	7.811e-15	79.0	COG0643@1|root,COG2199@1|root,COG0643@2|Bacteria,COG3706@2|Bacteria,1G26V@1117|Cyanobacteria,1JJEE@1189|Stigonemataceae	1117|Cyanobacteria	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158343_k127_246708_141	443143.GM18_3515	6.132e-91	318.0	COG1625@1|root,COG1625@2|Bacteria,1R76F@1224|Proteobacteria,42PNQ@68525|delta/epsilon subdivisions,2WKT9@28221|Deltaproteobacteria,43SDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
SRR25158343_k127_246708_145	926549.KI421517_gene3030	1.432e-90	304.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Fer4,Lactamase_B
SRR25158343_k127_246708_408	4792.ETI33489	3.351e-09	68.0	COG3914@1|root,KOG4626@2759|Eukaryota,3Q8CX@4776|Peronosporales	4776|Peronosporales	GOT	Glycosyl transferase family 41	-	-	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
SRR25158343_k127_246708_169	46429.BV95_02932	8.791e-76	264.0	COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,2U5FS@28211|Alphaproteobacteria,2K3WS@204457|Sphingomonadales	204457|Sphingomonadales	M	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
SRR25158343_k127_246708_238	247490.KSU1_D0503	1.073e-50	197.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158343_k127_246708_151	525904.Tter_0241	3.706e-86	296.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158343_k127_246708_206	153721.MYP_2628	1.332e-59	212.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,47JIZ@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158343_k127_246708_73	118163.Ple7327_1120	2.043e-147	472.0	COG0596@1|root,COG0596@2|Bacteria,1G21Y@1117|Cyanobacteria,3VI18@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158343_k127_246708_428	572546.Arcpr_1099	2.141e-06	53.0	COG1826@1|root,arCOG02694@2157|Archaea,2XZZ6@28890|Euryarchaeota,246CG@183980|Archaeoglobi	183980|Archaeoglobi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158343_k127_246708_457	448385.sce8618	0.000512	51.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158343_k127_246708_404	114615.BRADO3890	2.724e-10	65.0	2EN2V@1|root,33FR1@2|Bacteria,1NJXZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_170	1307436.PBF_11482	2.265e-75	260.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,1ZB50@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158343_k127_246708_29	1266925.JHVX01000002_gene842	7.716e-214	677.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VJQV@28216|Betaproteobacteria,3720X@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158343_k127_246708_454	713586.KB900536_gene1761	0.000458	48.0	COG1977@1|root,COG1977@2|Bacteria,1NHG7@1224|Proteobacteria,1TK6F@1236|Gammaproteobacteria,1WZUM@135613|Chromatiales	135613|Chromatiales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158343_k127_246708_278	1267533.KB906737_gene1631	7.696e-41	159.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria,2JMGK@204432|Acidobacteriia	204432|Acidobacteriia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158343_k127_246708_224	1229172.JQFA01000002_gene4447	8.996e-56	200.0	COG0317@1|root,COG0317@2|Bacteria,1G7H6@1117|Cyanobacteria,1HE76@1150|Oscillatoriales	1117|Cyanobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158343_k127_246708_120	234267.Acid_0264	2.82e-103	359.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
SRR25158343_k127_246708_429	1291050.JAGE01000001_gene1415	3.478e-06	59.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WK39@541000|Ruminococcaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4
SRR25158343_k127_246708_335	42256.RradSPS_0292	2.741e-29	126.0	COG2802@1|root,COG2802@2|Bacteria,2HP4R@201174|Actinobacteria,4CQGD@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
SRR25158343_k127_246708_162	1487953.JMKF01000056_gene4491	4.243e-79	279.0	COG0420@1|root,COG0420@2|Bacteria,1G36T@1117|Cyanobacteria,1HAG7@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA repair exonuclease	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
SRR25158343_k127_246708_193	926550.CLDAP_23740	1.363e-66	237.0	COG1218@1|root,COG1218@2|Bacteria	2|Bacteria	P	3'(2'),5'-bisphosphate nucleotidase activity	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158343_k127_246708_125	864702.OsccyDRAFT_1712	3.282e-100	334.0	COG4221@1|root,COG4221@2|Bacteria,1G2X4@1117|Cyanobacteria,1HA68@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_246708_177	1185876.BN8_06144	2.566e-72	247.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
SRR25158343_k127_246708_39	243231.GSU2317	9.298e-192	615.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
SRR25158343_k127_246708_149	1123371.ATXH01000016_gene1819	1.804e-87	298.0	COG0157@1|root,COG0157@2|Bacteria,2GHBY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158343_k127_246708_309	1216932.CM240_2970	5.667e-34	142.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,248TA@186801|Clostridia,36ESX@31979|Clostridiaceae	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158343_k127_246708_123	204669.Acid345_1393	3.039e-101	357.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria,2JIN2@204432|Acidobacteriia	204432|Acidobacteriia	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
SRR25158343_k127_246708_64	1340493.JNIF01000003_gene2599	2.605e-155	502.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_246708_430	272123.Anacy_0135	3.649e-06	57.0	COG4276@1|root,COG4276@2|Bacteria,1G9U4@1117|Cyanobacteria,1HN5F@1161|Nostocales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_424	767434.Fraau_0164	4.862e-07	60.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1X5Z4@135614|Xanthomonadales	135614|Xanthomonadales	NU	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158343_k127_246708_140	1198114.AciX9_1495	1.015e-91	313.0	COG1044@1|root,COG1044@2|Bacteria,3Y2JC@57723|Acidobacteria,2JI2Y@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SRR25158343_k127_246708_293	1249627.D779_1330	6.272e-37	148.0	COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,1S823@1236|Gammaproteobacteria,1WYPU@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158343_k127_246708_35	234267.Acid_0690	5.979e-203	659.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158343_k127_246708_305	56780.SYN_02178	4.542e-34	138.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2MQDY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158343_k127_246708_200	56780.SYN_02178	1.135e-62	228.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2MQDY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158343_k127_246708_113	293826.Amet_2788	1.968e-107	362.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,36DPK@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158343_k127_246708_263	1121468.AUBR01000002_gene656	3.025e-44	172.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,42FIH@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158343_k127_246708_158	290315.Clim_1585	1.912e-83	286.0	COG1562@1|root,COG1562@2|Bacteria,1FD9U@1090|Chlorobi	1090|Chlorobi	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158343_k127_246708_295	98439.AJLL01000090_gene68	1.8e-36	148.0	COG2340@1|root,COG2340@2|Bacteria,1G766@1117|Cyanobacteria,1JJRU@1189|Stigonemataceae	1117|Cyanobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,PPC
SRR25158343_k127_246708_412	118163.Ple7327_2400	1.99e-08	61.0	2EE59@1|root,337ZW@2|Bacteria,1G955@1117|Cyanobacteria,3VMXN@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_354	204669.Acid345_3695	8.439e-24	103.0	2BYAI@1|root,315Y9@2|Bacteria,3Y52S@57723|Acidobacteria,2JJJK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_363	330214.NIDE2908	2.762e-21	96.0	COG3536@1|root,COG3536@2|Bacteria,3J1AV@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
SRR25158343_k127_246708_371	1382305.AZUC01000007_gene1509	1.901e-19	91.0	COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,26GF0@186818|Planococcaceae	91061|Bacilli	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
SRR25158343_k127_246708_442	234267.Acid_5585	0.0001362	52.0	COG5523@1|root,COG5523@2|Bacteria	2|Bacteria	T	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
SRR25158343_k127_246708_25	1173022.Cri9333_3473	3.837e-216	692.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria,1HA6X@1150|Oscillatoriales	1117|Cyanobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158343_k127_246708_228	159087.Daro_1928	2.998e-55	199.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KWIF@206389|Rhodocyclales	206389|Rhodocyclales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158343_k127_246708_292	1166018.FAES_4690	2.309e-37	149.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,47PEA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_94	401053.AciPR4_1768	2.505e-125	409.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158343_k127_246708_33	234267.Acid_3724	5.137e-206	653.0	COG2234@1|root,COG2234@2|Bacteria,3Y4CJ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158343_k127_246708_396	321332.CYB_1277	7.156e-13	81.0	2EEBA@1|root,3385M@2|Bacteria,1GABH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_121	1047013.AQSP01000055_gene266	2.217e-102	342.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158343_k127_246708_45	639282.DEFDS_0115	3.821e-182	578.0	COG1004@1|root,COG1004@2|Bacteria,2GF0F@200930|Deferribacteres	200930|Deferribacteres	C	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158343_k127_246708_56	251221.35213042	1.157e-164	537.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158343_k127_246708_194	555079.Toce_1809	3.024e-66	237.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
SRR25158343_k127_246708_320	754477.Q7C_578	8.802e-33	133.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,460YH@72273|Thiotrichales	72273|Thiotrichales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158343_k127_246708_111	1267535.KB906767_gene3803	3.355e-109	371.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria,2JIAX@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SRR25158343_k127_246708_28	1382359.JIAL01000001_gene1877	6.167e-214	696.0	COG0532@1|root,COG0532@2|Bacteria,3Y3UG@57723|Acidobacteria,2JHXH@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158343_k127_246708_385	562970.Btus_1542	1.988e-16	83.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,278JM@186823|Alicyclobacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158343_k127_246708_167	204669.Acid345_4214	1.08e-76	269.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158343_k127_246708_236	1485545.JQLW01000009_gene213	3.798e-51	187.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria	1224|Proteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158343_k127_246708_152	1379698.RBG1_1C00001G0812	2.116e-85	287.0	COG0177@1|root,COG0177@2|Bacteria,2NPBI@2323|unclassified Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158343_k127_246708_86	886293.Sinac_3294	7.422e-134	436.0	COG0399@1|root,COG0399@2|Bacteria,2IXRE@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158343_k127_246708_239	1267535.KB906767_gene3613	1.2e-50	190.0	COG1183@1|root,COG1183@2|Bacteria,3Y3I7@57723|Acidobacteria,2JIEG@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158343_k127_246708_250	1123511.KB905853_gene3725	1.435e-46	175.0	COG0688@1|root,COG0688@2|Bacteria,1V3FQ@1239|Firmicutes,4H45T@909932|Negativicutes	909932|Negativicutes	I	Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158343_k127_246708_375	1128421.JAGA01000001_gene2128	1.42e-18	86.0	2BWQN@1|root,347D7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_112	243231.GSU0094	1.315e-107	373.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158343_k127_246708_440	1231185.BAMP01000117_gene1490	4.89e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_246708_414	1550073.JROH01000009_gene1300	3.677e-08	55.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_246708_257	667014.Thein_1912	1.21e-45	169.0	COG0590@1|root,COG0590@2|Bacteria,2GHG8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158343_k127_246708_243	491915.Aflv_1798	4.944e-49	193.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,21VEU@150247|Anoxybacillus	91061|Bacilli	K	Fibronectin-binding protein A N-terminus (FbpA)	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SRR25158343_k127_246708_435	570952.ATVH01000011_gene179	1.125e-05	58.0	COG1714@1|root,COG1714@2|Bacteria,1Q20I@1224|Proteobacteria,2V9JC@28211|Alphaproteobacteria,2JTX1@204441|Rhodospirillales	204441|Rhodospirillales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158343_k127_246708_365	1379698.RBG1_1C00001G0819	3.57e-21	98.0	COG4911@1|root,COG4911@2|Bacteria,2NQ4H@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158343_k127_246708_207	1165094.RINTHH_20180	1.903e-59	214.0	COG1432@1|root,COG1432@2|Bacteria,1G3J6@1117|Cyanobacteria,1HKVX@1161|Nostocales	1117|Cyanobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158343_k127_246708_184	1329516.JPST01000015_gene737	3.135e-69	245.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,27B1W@186824|Thermoactinomycetaceae	91061|Bacilli	J	RNA 2'-O ribose methyltransferase substrate binding	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158343_k127_246708_451	877455.Metbo_2028	0.0003474	51.0	arCOG01917@1|root,arCOG01917@2157|Archaea	2157|Archaea	M	deoxyhypusine monooxygenase activity	-	-	-	ko:K21463	-	-	-	-	ko00000	-	-	-	zinc_ribbon_2
SRR25158343_k127_246708_91	234267.Acid_0265	1.231e-128	437.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
SRR25158343_k127_246708_108	479434.Sthe_0801	5.823e-115	380.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158343_k127_246708_129	237368.SCABRO_03813	2.504e-98	341.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SRR25158343_k127_246708_260	926550.CLDAP_15070	3.932e-45	172.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	M1-693	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
SRR25158343_k127_246708_249	1121346.KB899820_gene2776	3.67e-47	186.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,26RTN@186822|Paenibacillaceae	91061|Bacilli	GK	ROK family	xylR5	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_27,HTH_IclR,ROK
SRR25158343_k127_246708_110	204669.Acid345_3201	1.437e-111	369.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria,2JKTE@204432|Acidobacteriia	204432|Acidobacteriia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158343_k127_246708_323	321327.CYA_2265	2.553e-32	143.0	COG1721@1|root,COG1721@2|Bacteria,1G15B@1117|Cyanobacteria,1GZR9@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158343_k127_246708_373	1382356.JQMP01000003_gene1789	2.881e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_246708_441	580327.Tthe_0345	7.341e-05	54.0	COG5662@1|root,COG5662@2|Bacteria,1U13D@1239|Firmicutes,24AF3@186801|Clostridia,42FDE@68295|Thermoanaerobacterales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,DUF4367,zf-HC2
SRR25158343_k127_246708_419	1515746.HR45_10025	2.202e-07	63.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,2Q9SH@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158343_k127_246708_426	261292.Nit79A3_2343	8.247e-07	60.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
SRR25158343_k127_246708_417	1007104.SUS17_932	1.59e-07	65.0	2C9DE@1|root,2Z8R4@2|Bacteria,1NVMQ@1224|Proteobacteria,2U51M@28211|Alphaproteobacteria,2K0UF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_294	1197477.IA57_02270	7.851e-37	157.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1HYRA@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4
SRR25158343_k127_246708_382	926566.Terro_1495	1.398e-17	96.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158343_k127_246708_3	443143.GM18_2076	0.0	1178.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,43U5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SRR25158343_k127_246708_403	1249480.B649_11415	1.68e-10	67.0	2CCD9@1|root,32NJ2@2|Bacteria,1Q3UE@1224|Proteobacteria,42XU5@68525|delta/epsilon subdivisions,2YQSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
SRR25158343_k127_246708_266	204669.Acid345_1037	3.724e-43	179.0	COG3595@1|root,COG3595@2|Bacteria,3Y97I@57723|Acidobacteria,2JNRB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_142	1379698.RBG1_1C00001G1080	6.557e-91	330.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158343_k127_246708_296	879212.DespoDRAFT_01679	2.252e-36	154.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,43B47@68525|delta/epsilon subdivisions,2X6I0@28221|Deltaproteobacteria,2MPUU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
SRR25158343_k127_246708_310	498848.TaqDRAFT_4855	7.219e-34	141.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158343_k127_246708_136	204669.Acid345_4746	8.596e-94	316.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158343_k127_246708_137	696369.KI912183_gene2381	1.385e-93	314.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26011@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158343_k127_246708_407	641143.HMPREF9331_01803	3.287e-09	64.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia,1ER40@1016|Capnocytophaga	976|Bacteroidetes	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
SRR25158343_k127_246708_242	234267.Acid_1082	4.238e-49	182.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria	57723|Acidobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158343_k127_246708_438	1415166.NONO_c00100	3.487e-05	52.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158343_k127_246708_398	1230341.MJ3_03312	2.045e-12	71.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158343_k127_246708_55	697303.Thewi_0693	1.386e-165	533.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158343_k127_246708_81	272134.KB731324_gene3218	9.33e-141	466.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MHYT,PAS,PAS_3,PAS_9
SRR25158343_k127_246708_18	1121920.AUAU01000004_gene641	7.583e-239	757.0	COG1770@1|root,COG1770@2|Bacteria,3Y3PK@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9A, prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158343_k127_246708_273	234267.Acid_5135	1.65e-41	160.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Z3@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_246708_342	234267.Acid_3522	2.049e-27	119.0	2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
SRR25158343_k127_246708_409	1267535.KB906767_gene3333	4.68e-09	64.0	2EGKM@1|root,33ACV@2|Bacteria,3Y5U1@57723|Acidobacteria,2JK61@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_84	562970.Btus_2368	1.755e-136	444.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158343_k127_246708_187	1158345.JNLL01000001_gene1904	8.415e-69	241.0	COG1912@1|root,COG1912@2|Bacteria,2G44H@200783|Aquificae	200783|Aquificae	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158343_k127_246708_448	1267534.KB906755_gene4292	0.0001942	53.0	2A87I@1|root,30X8J@2|Bacteria,3Y4II@57723|Acidobacteria,2JJBN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbI
SRR25158343_k127_246708_253	1340493.JNIF01000004_gene505	4.205e-46	182.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_246708_433	1499967.BAYZ01000009_gene5337	9.376e-06	56.0	2EKNX@1|root,33ECP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_227	319795.Dgeo_0362	1.523e-55	206.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158343_k127_246708_67	1005058.UMN179_01250	4.11e-153	496.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1Y79S@135625|Pasteurellales	135625|Pasteurellales	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158343_k127_246708_348	1123508.JH636456_gene134	2.931e-25	118.0	COG2202@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3,STAS
SRR25158343_k127_246708_247	1504672.669784484	2.201e-48	186.0	COG2202@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WHG2@28216|Betaproteobacteria,4AJX0@80864|Comamonadaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
SRR25158343_k127_246708_380	583355.Caka_1913	7.039e-18	95.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158343_k127_246708_276	404380.Gbem_2640	4.036e-41	165.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43U6A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158343_k127_246708_16	204669.Acid345_0064	3.02e-245	773.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158343_k127_246708_161	1379698.RBG1_1C00001G1625	2.887e-80	276.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158343_k127_246708_379	204669.Acid345_2357	6.088e-18	91.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria,2JJKB@204432|Acidobacteriia	204432|Acidobacteriia	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SRR25158343_k127_246708_268	1403313.AXBR01000008_gene621	1.727e-42	169.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158343_k127_246708_390	1382359.JIAL01000001_gene2110	3.766e-15	78.0	COG0268@1|root,COG0268@2|Bacteria,3Y5CZ@57723|Acidobacteria,2JJS9@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158343_k127_246708_401	1123371.ATXH01000018_gene1364	4.14e-11	73.0	COG0484@1|root,COG0484@2|Bacteria,2GIGH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	DnaJ central domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158343_k127_246708_395	1340493.JNIF01000003_gene1846	3.275e-13	76.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158343_k127_246708_179	1449126.JQKL01000009_gene363	3.726e-71	260.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26ARS@186813|unclassified Clostridiales	186801|Clostridia	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158343_k127_246708_122	1267535.KB906767_gene2479	7.134e-102	348.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria,2JI3B@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158343_k127_246708_306	1123059.KB823011_gene1558	4.626e-34	133.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2U9EX@28211|Alphaproteobacteria,43Y4W@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158343_k127_246708_271	204669.Acid345_2199	4.424e-42	166.0	COG1725@1|root,COG1725@2|Bacteria,3Y8PU@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158343_k127_246708_319	880072.Desac_0441	8.515e-33	144.0	COG0515@1|root,COG2199@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,1PEAT@1224|Proteobacteria,4306N@68525|delta/epsilon subdivisions,2WVD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_246708_114	525904.Tter_0425	1.539e-105	352.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158343_k127_246708_366	1540221.JQNI01000002_gene1515	6.015e-21	100.0	arCOG13559@1|root,33239@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRR25158343_k127_246708_106	1191523.MROS_0617	6.553e-116	384.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158343_k127_246708_180	655815.ZPR_1903	3.93e-71	243.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,1I1ZI@117743|Flavobacteriia	976|Bacteroidetes	FJ	deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158343_k127_246708_311	1232410.KI421413_gene468	7.321e-34	136.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,42U5S@68525|delta/epsilon subdivisions,2WQRJ@28221|Deltaproteobacteria,43SQN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158343_k127_246708_72	714943.Mucpa_6423	1.241e-148	483.0	COG4630@1|root,COG4630@2|Bacteria,4NI8H@976|Bacteroidetes,1IQYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM 2Fe-2S -binding	-	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158343_k127_246708_4	700598.Niako_0452	0.0	1061.0	COG4631@1|root,COG4631@2|Bacteria,4PMEG@976|Bacteroidetes,1IPUS@117747|Sphingobacteriia	976|Bacteroidetes	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158343_k127_246708_159	926549.KI421517_gene1629	1.058e-81	283.0	COG1975@1|root,COG1975@2|Bacteria,4NJH1@976|Bacteroidetes,47NXR@768503|Cytophagia	976|Bacteroidetes	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158343_k127_246708_213	365044.Pnap_2179	2.67e-58	209.0	COG3212@1|root,COG3212@2|Bacteria,1N0D3@1224|Proteobacteria	1224|Proteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRR25158343_k127_246708_312	1519464.HY22_10210	8.621e-34	136.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3,AhpC-TSA
SRR25158343_k127_246708_374	379066.GAU_0167	8.978e-19	89.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SRR25158343_k127_246708_31	247490.KSU1_C0443	3.828e-210	672.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
SRR25158343_k127_246708_226	1267535.KB906767_gene4055	1.354e-55	217.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
SRR25158343_k127_246708_270	1382359.JIAL01000001_gene1949	1.884e-42	160.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158343_k127_246708_155	1121468.AUBR01000006_gene356	1.78e-84	290.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,42EWY@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158343_k127_246708_104	204669.Acid345_3635	2.911e-117	402.0	COG0768@1|root,COG0768@2|Bacteria,3Y2XX@57723|Acidobacteria,2JHPS@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158343_k127_246708_146	204669.Acid345_3633	1.312e-89	312.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_246708_115	1047013.AQSP01000140_gene2478	3.825e-105	353.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
SRR25158343_k127_246708_103	1382359.JIAL01000001_gene1975	7.162e-118	394.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_246708_148	204669.Acid345_3630	4.634e-88	304.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158343_k127_246708_135	443143.GM18_3887	4.751e-94	321.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,43UB0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158343_k127_246708_58	1121403.AUCV01000008_gene1508	1.607e-161	520.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_246708_406	338963.Pcar_2198	2.495e-09	68.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,43SIM@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	POTRA domain, FtsQ-type	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158343_k127_246708_126	269799.Gmet_0416	2.518e-99	338.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158343_k127_246708_98	204669.Acid345_3451	5.079e-122	402.0	COG0206@1|root,COG0206@2|Bacteria,3Y2WG@57723|Acidobacteria,2JHRJ@204432|Acidobacteriia	204432|Acidobacteriia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158343_k127_246708_362	1267535.KB906767_gene2339	1.061e-21	98.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria,2JNEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
SRR25158343_k127_246708_154	555079.Toce_0654	2.519e-85	294.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,42FJX@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158343_k127_246708_389	316274.Haur_4036	2.817e-15	80.0	COG0745@1|root,COG0745@2|Bacteria,2G8CZ@200795|Chloroflexi,375CM@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_246708_329	243231.GSU2046	4.577e-31	137.0	COG0745@1|root,COG0745@2|Bacteria,1NER5@1224|Proteobacteria,42VHC@68525|delta/epsilon subdivisions,2WSGQ@28221|Deltaproteobacteria,43UMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158343_k127_246708_14	269799.Gmet_0956	3.344e-266	848.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158343_k127_246708_212	1340493.JNIF01000003_gene2851	1.141e-58	216.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,HEAT_2
SRR25158343_k127_246708_456	267377.MMP0827	0.0004874	46.0	arCOG03453@1|root,arCOG03453@2157|Archaea,2Y50E@28890|Euryarchaeota,23RRD@183939|Methanococci	183939|Methanococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_71	330214.NIDE0026	2.151e-150	488.0	COG1252@1|root,COG1252@2|Bacteria,3J12C@40117|Nitrospirae	40117|Nitrospirae	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_246708_117	3218.PP1S46_300V6.1	2.614e-104	350.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_246708_92	1449126.JQKL01000021_gene73	1.2e-125	421.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,267UW@186813|unclassified Clostridiales	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_246708_234	1379698.RBG1_1C00001G1716	2.352e-51	200.0	COG0544@1|root,COG0544@2|Bacteria,2NPBN@2323|unclassified Bacteria	2|Bacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158343_k127_246708_153	864563.HMPREF9166_0751	2.422e-85	286.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4H2XP@909932|Negativicutes	909932|Negativicutes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158343_k127_246708_52	671143.DAMO_2181	1.186e-168	539.0	COG1219@1|root,COG1219@2|Bacteria,2NNN2@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158343_k127_246708_314	714943.Mucpa_6549	5.73e-33	134.0	2DN7D@1|root,32VY2@2|Bacteria,4NTEH@976|Bacteroidetes,1J140@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158343_k127_246708_298	1131730.BAVI_00170	1.711e-35	139.0	COG3607@1|root,COG3607@2|Bacteria,1VF7V@1239|Firmicutes,4HKER@91061|Bacilli,1ZR2B@1386|Bacillus	91061|Bacilli	S	Extradiol dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158343_k127_246708_302	192952.MM_0012	6.98e-35	136.0	COG5507@1|root,arCOG09468@2157|Archaea,2Y13Q@28890|Euryarchaeota,2NB85@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
SRR25158343_k127_246708_215	761193.Runsl_0545	1.108e-57	205.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,47QQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRR25158343_k127_246708_222	468059.AUHA01000002_gene379	6.48e-56	201.0	COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1J056@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158343_k127_246708_233	1121895.Q765_19295	2.005e-51	184.0	COG3324@1|root,COG3324@2|Bacteria,4NRUY@976|Bacteroidetes,1I3NB@117743|Flavobacteriia	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158343_k127_246708_85	1237149.C900_03010	3.87e-135	437.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,47JXN@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	xylR	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158343_k127_246708_356	1121920.AUAU01000001_gene2169	2.855e-23	108.0	2919Q@1|root,32TZW@2|Bacteria,3Y5IU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_346	1134912.AJTV01000002_gene1748	4.682e-26	117.0	2AC8B@1|root,311T0@2|Bacteria,1NK0P@1224|Proteobacteria,2VD5M@28211|Alphaproteobacteria,3713U@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_24	1406840.Q763_15640	1.131e-217	685.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
SRR25158343_k127_246708_339	379066.GAU_3293	4.12e-28	118.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
SRR25158343_k127_246708_334	395961.Cyan7425_0500	5.948e-30	119.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,3KIU5@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158343_k127_246708_434	661478.OP10G_3996	9.87e-06	48.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158343_k127_246708_402	1123508.JH636444_gene5535	1.273e-10	68.0	COG4296@1|root,COG4296@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2262)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2262
SRR25158343_k127_246708_1	755178.Cyan10605_2363	0.0	1358.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1G0PS@1117|Cyanobacteria	1117|Cyanobacteria	H	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158343_k127_246708_388	1185876.BN8_04235	2.09e-15	78.0	COG5466@1|root,COG5466@2|Bacteria,4NVUX@976|Bacteroidetes,47SA9@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158343_k127_246708_83	1379698.RBG1_1C00001G0798	3.471e-139	475.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
SRR25158343_k127_246708_307	1392489.JPOL01000002_gene2816	4.976e-34	139.0	COG5403@1|root,COG5403@2|Bacteria,4NEX0@976|Bacteroidetes,1HYHW@117743|Flavobacteriia,2XJCV@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158343_k127_246708_134	454957.IA64_19735	4.614e-94	333.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,1SZ73@1236|Gammaproteobacteria,1X33T@135614|Xanthomonadales	135614|Xanthomonadales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158343_k127_246708_166	395493.BegalDRAFT_1731	2.443e-78	284.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,45ZRX@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158343_k127_246708_282	247490.KSU1_D0595	8.238e-39	164.0	COG0265@1|root,COG0265@2|Bacteria,2J23K@203682|Planctomycetes	203682|Planctomycetes	OT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
SRR25158343_k127_246708_386	709986.Deima_0770	2.096e-16	83.0	2EDR5@1|root,3321U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_60	204669.Acid345_2712	1.391e-160	523.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SRR25158343_k127_246708_437	880073.Calab_3334	2.971e-05	55.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
SRR25158343_k127_246708_458	525146.Ddes_1237	0.0005261	52.0	29W60@1|root,30HR4@2|Bacteria,1RJNX@1224|Proteobacteria,42T35@68525|delta/epsilon subdivisions,2WP20@28221|Deltaproteobacteria,2M98P@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
SRR25158343_k127_246708_160	1123376.AUIU01000019_gene1250	1.999e-81	287.0	COG0373@1|root,COG0373@2|Bacteria,3J0BD@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158343_k127_246708_330	269799.Gmet_2901	5.198e-31	139.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,43SZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158343_k127_246708_231	204669.Acid345_0749	4.037e-53	207.0	COG0755@1|root,COG0755@2|Bacteria,3Y3QF@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158343_k127_246708_413	290397.Adeh_2980	2.467e-08	64.0	COG4235@1|root,COG4235@2|Bacteria,1RITV@1224|Proteobacteria,43CCM@68525|delta/epsilon subdivisions,2X7NI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
SRR25158343_k127_246708_46	880073.Calab_3390	2.407e-179	569.0	COG1740@1|root,COG1740@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	hyaA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_76,iUTI89_1310.UTI89_C1040	NiFe_hyd_SSU_C,Oxidored_q6
SRR25158343_k127_246708_8	880073.Calab_3389	5.031e-298	921.0	COG0374@1|root,COG0374@2|Bacteria	2|Bacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iSbBS512_1146.SbBS512_E2342	NiFeSe_Hases
SRR25158343_k127_246708_144	880073.Calab_3388	1.13e-90	304.0	COG1969@1|root,COG1969@2|Bacteria	2|Bacteria	C	respiratory electron transport chain	cybH	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158343_k127_246708_289	714943.Mucpa_5243	1.373e-37	148.0	COG0680@1|root,COG0680@2|Bacteria,4NRQY@976|Bacteroidetes,1IT7D@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0680 Ni Fe-hydrogenase maturation factor	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158343_k127_246708_359	1249997.JHZW01000002_gene1817	1.355e-22	104.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_246708_93	925409.KI911562_gene548	2.216e-125	407.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1IP1D@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158343_k127_246708_53	929713.NIASO_19955	3.773e-168	540.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
SRR25158343_k127_246708_5	700598.Niako_0114	0.0	1048.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
SRR25158343_k127_246708_32	398767.Glov_2503	1.648e-207	661.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,43SU0@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158343_k127_246708_420	479435.Kfla_4887	3.03e-07	57.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4DQCD@85009|Propionibacteriales	201174|Actinobacteria	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158343_k127_246708_63	330214.NIDE0999	6.783e-156	497.0	COG0059@1|root,COG0059@2|Bacteria,3J0DW@40117|Nitrospirae	40117|Nitrospirae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158343_k127_246708_447	338966.Ppro_0731	0.0001911	49.0	COG1917@1|root,COG1917@2|Bacteria,1RHSW@1224|Proteobacteria,42TSH@68525|delta/epsilon subdivisions,2WQ63@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_246708_116	1448860.BBJO01000003_gene2660	1.278e-104	348.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,23SQX@183963|Halobacteria	183963|Halobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158343_k127_246708_199	742738.HMPREF9460_01964	4.421e-63	231.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,268HD@186813|unclassified Clostridiales	186801|Clostridia	E	Chorismate mutase type II	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158343_k127_246708_42	1123368.AUIS01000001_gene1868	8.802e-191	600.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,1S11K@1236|Gammaproteobacteria,2NBQA@225057|Acidithiobacillales	225057|Acidithiobacillales	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158343_k127_246708_119	525904.Tter_0227	1.391e-103	347.0	COG1171@1|root,COG1171@2|Bacteria,2NQCM@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0000287,GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006464,GO:0006520,GO:0006549,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008838,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009071,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0031406,GO:0032787,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.3.1.263,3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989,ko:K21400	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2699,iECED1_1282.ECED1_3331,iJN678.ilvA,iLJ478.TM0356,iNJ661.Rv1559	PALP,Thr_dehydrat_C
SRR25158343_k127_246708_13	1173022.Cri9333_1348	4.292e-273	848.0	COG0129@1|root,COG0129@2|Bacteria,1G0KD@1117|Cyanobacteria,1H8V6@1150|Oscillatoriales	1117|Cyanobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158343_k127_246708_0	398512.JQKC01000033_gene5010	0.0	1987.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158343_k127_246708_36	720554.Clocl_0015	9.197e-195	618.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158343_k127_246708_259	861299.J421_6107	2.392e-45	168.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158343_k127_246708_191	696281.Desru_0916	4.71e-67	239.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia,264GJ@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158343_k127_246708_355	289376.THEYE_A1338	1.926e-23	104.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158343_k127_246708_303	525244.HMPREF0023_0346	9.679e-35	141.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S28H@1236|Gammaproteobacteria,3NJTE@468|Moraxellaceae	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158343_k127_246708_38	1123058.KB894281_gene1769	2.923e-192	631.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158343_k127_246708_322	596151.DesfrDRAFT_1284	2.015e-32	132.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,42T6V@68525|delta/epsilon subdivisions,2WPNI@28221|Deltaproteobacteria,2MC1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158343_k127_246708_100	118173.KB235910_gene5084	2.474e-121	402.0	COG0389@1|root,COG0389@2|Bacteria,1G07F@1117|Cyanobacteria,1H6YS@1150|Oscillatoriales	1117|Cyanobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
SRR25158343_k127_246708_304	1303518.CCALI_01081	4.328e-34	148.0	COG0515@1|root,COG0515@2|Bacteria	1303518.CCALI_01081|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_246708_128	234267.Acid_7262	9.651e-99	331.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_352	1453503.AU05_21485	7.006e-24	103.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1YGFT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
SRR25158343_k127_246708_165	1267535.KB906767_gene4415	1.208e-78	276.0	COG1044@1|root,COG1044@2|Bacteria,3Y6ZT@57723|Acidobacteria	57723|Acidobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
SRR25158343_k127_246708_392	401053.AciPR4_2583	8.51e-15	79.0	2EC48@1|root,33633@2|Bacteria,3Y5ER@57723|Acidobacteria,2JJVN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_291	886293.Sinac_0326	2.25e-37	154.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_246708_22	1358423.N180_18665	9.013e-221	705.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158343_k127_246708_59	204669.Acid345_2858	3.919e-161	541.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	2|Bacteria	I	Phosphate acyltransferases	fadD	-	2.3.1.51,6.2.1.3	ko:K00655,ko:K01897	ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00089	R01280,R02241,R09381	RC00004,RC00014,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
SRR25158343_k127_246708_205	502025.Hoch_2148	5.334e-61	222.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158343_k127_246708_258	1278073.MYSTI_03333	1.857e-45	175.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158343_k127_246708_171	1318628.MARLIPOL_14805	1.026e-74	257.0	COG2129@1|root,COG2129@2|Bacteria,1RFU9@1224|Proteobacteria,1S4S2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphoesterases, related to the Icc protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158343_k127_246708_101	1341181.FLJC2902T_18350	3.082e-120	396.0	COG1748@1|root,COG1748@2|Bacteria,4PDGG@976|Bacteroidetes,1I0IM@117743|Flavobacteriia,2NTRF@237|Flavobacterium	976|Bacteroidetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158343_k127_246708_9	682795.AciX8_3208	2.674e-293	920.0	COG0466@1|root,COG0466@2|Bacteria,3Y3DI@57723|Acidobacteria,2JIB4@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158343_k127_246708_318	1267535.KB906767_gene2786	8.121e-33	133.0	2DB97@1|root,32TX2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_214	903814.ELI_3523	4.165e-58	208.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,25VE4@186806|Eubacteriaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158343_k127_246708_21	1267535.KB906767_gene3177	2.668e-224	703.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158343_k127_246708_325	1177154.Y5S_00479	7.571e-32	131.0	294RE@1|root,2ZS4P@2|Bacteria,1P9TN@1224|Proteobacteria,1SV2K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_418	1382359.JIAL01000001_gene985	1.767e-07	62.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158343_k127_246708_109	945713.IALB_0042	4.328e-112	378.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158343_k127_246708_265	1385510.N781_13785	3.663e-43	163.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,2YAFC@289201|Pontibacillus	91061|Bacilli	J	acetyltransferase	ydaF	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158343_k127_246708_74	941824.TCEL_02067	8.088e-147	477.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,36EP1@31979|Clostridiaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158343_k127_246708_269	309807.SRU_2855	1.756e-42	165.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1FJ14@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158343_k127_246708_12	1267535.KB906767_gene4053	3.884e-277	876.0	COG1629@1|root,COG4771@2|Bacteria,3Y36N@57723|Acidobacteria,2JI4W@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158343_k127_246708_77	452637.Oter_3899	2.361e-145	481.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46UA9@74201|Verrucomicrobia,3K7MZ@414999|Opitutae	414999|Opitutae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
SRR25158343_k127_246708_235	1123399.AQVE01000001_gene529	3.528e-51	192.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158343_k127_246708_337	1121920.AUAU01000014_gene2807	1.675e-28	122.0	COG0558@1|root,COG0558@2|Bacteria,3Y4S5@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158343_k127_246708_349	931626.Awo_c00810	3.837e-25	109.0	2AFFK@1|root,315FP@2|Bacteria,1U4XW@1239|Firmicutes,256TB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_10	1499967.BAYZ01000026_gene1569	5.81e-292	908.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158343_k127_246708_105	1382359.JIAL01000001_gene2461	1.792e-116	387.0	COG0484@1|root,COG0484@2|Bacteria,3Y2XW@57723|Acidobacteria,2JHWV@204432|Acidobacteriia	204432|Acidobacteriia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158343_k127_246708_290	1267535.KB906767_gene2804	1.608e-37	145.0	COG0789@1|root,COG0789@2|Bacteria,3Y4KX@57723|Acidobacteria,2JJA1@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158343_k127_246708_208	1267534.KB906758_gene2303	2.193e-59	236.0	COG1629@1|root,COG4771@2|Bacteria,3Y77Y@57723|Acidobacteria,2JKVG@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_246708_461	706587.Desti_0302	0.0008446	50.0	COG0745@1|root,COG0745@2|Bacteria	706587.Desti_0302|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_97	574087.Acear_1673	1.484e-122	437.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WAB0@53433|Halanaerobiales	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158343_k127_246708_2	1121930.AQXG01000002_gene2043	0.0	1220.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158343_k127_246708_313	338966.Ppro_1729	8.767e-34	146.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158343_k127_246708_332	204669.Acid345_1215	4.017e-30	124.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria,2JJFX@204432|Acidobacteriia	204432|Acidobacteriia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158343_k127_246708_221	429009.Adeg_1979	4.458e-56	200.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,42G01@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158343_k127_246708_11	379066.GAU_2797	8.266e-290	909.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158343_k127_246708_378	204536.SULAZ_1302	5.836e-18	88.0	COG4783@1|root,COG4783@2|Bacteria,2G573@200783|Aquificae	200783|Aquificae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158343_k127_246708_57	1173025.GEI7407_1132	3.245e-164	550.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9
SRR25158343_k127_246708_185	1123401.JHYQ01000013_gene636	3.792e-69	241.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,460KC@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158343_k127_246708_364	1144275.COCOR_01355	2.885e-21	100.0	2BU8D@1|root,32PHV@2|Bacteria,1NANB@1224|Proteobacteria,433N8@68525|delta/epsilon subdivisions,2WXKZ@28221|Deltaproteobacteria,2YW2P@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
SRR25158343_k127_246708_367	929704.Myrod_1792	1.017e-20	104.0	COG3266@1|root,COG3266@2|Bacteria,4NMES@976|Bacteroidetes,1HYRQ@117743|Flavobacteriia,47H3A@76831|Myroides	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_150	1128421.JAGA01000003_gene3582	1.143e-86	298.0	COG0042@1|root,COG0042@2|Bacteria,2NP3E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158343_k127_246708_453	1088869.GMO_10510	0.0004408	52.0	COG0392@1|root,COG0392@2|Bacteria,1RF8R@1224|Proteobacteria,2U7DD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158343_k127_246708_49	264462.Bd1973	1.974e-171	545.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2MSRZ@213481|Bdellovibrionales,2WJ3Z@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	acyl-coa dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_246708_173	1254432.SCE1572_32230	2.084e-74	261.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,42U5B@68525|delta/epsilon subdivisions,2WQVN@28221|Deltaproteobacteria,2YWFF@29|Myxococcales	28221|Deltaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158343_k127_246708_297	335543.Sfum_0003	6.379e-36	139.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2MRZN@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158343_k127_246708_43	234267.Acid_1040	5.398e-189	614.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria	57723|Acidobacteria	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
SRR25158343_k127_246708_23	1303518.CCALI_00492	1.224e-220	704.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158343_k127_246708_88	880073.Calab_0801	7.36e-133	452.0	COG3591@1|root,COG3591@2|Bacteria,2NQEJ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase S46	-	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158343_k127_246708_284	888060.HMPREF9081_0577	1.87e-38	155.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4H4HE@909932|Negativicutes	909932|Negativicutes	M	Peptidase, M23 family	envC_2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158343_k127_246708_394	240015.ACP_1890	1.563e-13	79.0	2DMGW@1|root,32REM@2|Bacteria,3Y4XX@57723|Acidobacteria,2JJER@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
SRR25158343_k127_246708_252	234267.Acid_0793	2.388e-46	175.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_246708_347	1379698.RBG1_1C00001G1318	6.632e-26	121.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158343_k127_246708_204	278963.ATWD01000001_gene2151	3.815e-61	214.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria,2JJ32@204432|Acidobacteriia	204432|Acidobacteriia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158343_k127_246708_7	289376.THEYE_A0859	2.587e-299	938.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158343_k127_246708_209	338963.Pcar_2042	3.715e-59	227.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43S23@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158343_k127_246708_50	335543.Sfum_2637	2.852e-170	549.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MQX1@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158343_k127_246708_225	639030.JHVA01000001_gene1237	1.243e-55	202.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_246708_416	1047013.AQSP01000139_gene2326	1.509e-07	61.0	COG5660@1|root,COG5660@2|Bacteria	2|Bacteria	S	Putative zinc-finger	sigC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
SRR25158343_k127_246708_432	435591.BDI_2640	7.082e-06	57.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,2FV2Q@200643|Bacteroidia,22YZE@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_439	1443665.JACA01000020_gene5040	3.734e-05	55.0	COG3595@1|root,COG3595@2|Bacteria,4NGJ2@976|Bacteroidetes,1I063@117743|Flavobacteriia,2YGWJ@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_202	395494.Galf_0410	2.127e-62	220.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,44UYM@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158343_k127_246708_79	1227739.Hsw_0885	6.248e-145	476.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47M14@768503|Cytophagia	976|Bacteroidetes	G	Peptidase, M28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158343_k127_246708_357	1123288.SOV_4c02030	6.719e-23	115.0	COG0810@1|root,COG5263@1|root,COG0810@2|Bacteria,COG5263@2|Bacteria,1V30N@1239|Firmicutes,4H8HT@909932|Negativicutes	909932|Negativicutes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_285	700598.Niako_2300	2.508e-38	153.0	2CG8S@1|root,32S3E@2|Bacteria,4NS84@976|Bacteroidetes,1IXWY@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
SRR25158343_k127_246708_48	661478.OP10G_1570	3.398e-174	569.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,YARHG,zinc_ribbon_2
SRR25158343_k127_246708_340	661478.OP10G_1571	4.939e-28	121.0	2DMSI@1|root,32TE7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_223	643648.Slip_0641	7.721e-56	210.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap,Peptidase_M15
SRR25158343_k127_246708_279	1123288.SOV_4c02030	2.214e-40	175.0	COG0810@1|root,COG5263@1|root,COG0810@2|Bacteria,COG5263@2|Bacteria,1V30N@1239|Firmicutes,4H8HT@909932|Negativicutes	909932|Negativicutes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_264	565034.BHWA1_01643	5.792e-44	187.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRR25158343_k127_246708_397	1304872.JAGC01000005_gene1863	8.121e-13	84.0	COG0457@1|root,COG0457@2|Bacteria,1R10W@1224|Proteobacteria,43D4R@68525|delta/epsilon subdivisions,2X8BA@28221|Deltaproteobacteria,2MHFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158343_k127_246708_315	696747.NIES39_A00620	5.801e-33	148.0	COG0457@1|root,COG0457@2|Bacteria,1GMUY@1117|Cyanobacteria,1HFF9@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10,TPR_11
SRR25158343_k127_246708_361	944481.JAFP01000001_gene1635	1.021e-21	111.0	COG4254@1|root,COG5513@1|root,COG4254@2|Bacteria,COG5513@2|Bacteria,1R1RW@1224|Proteobacteria,42WV0@68525|delta/epsilon subdivisions,2WTHA@28221|Deltaproteobacteria,2M7DD@213113|Desulfurellales	28221|Deltaproteobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158343_k127_246708_70	1278073.MYSTI_05664	1.642e-151	495.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Aminotran_5,DUF4377,Lactamase_B,Rhodanese
SRR25158343_k127_246708_192	861299.J421_2096	5.934e-67	237.0	COG3279@1|root,COG3279@2|Bacteria,1ZTKG@142182|Gemmatimonadetes	2|Bacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	EAL,LytTR,Response_reg
SRR25158343_k127_246708_251	1163407.UU7_14910	1.483e-46	183.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158343_k127_246708_19	313606.M23134_00438	1.737e-235	736.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158343_k127_246708_30	1121286.AUMT01000003_gene1990	2.731e-210	668.0	COG1228@1|root,COG4538@1|root,COG1228@2|Bacteria,COG4538@2|Bacteria,4NGGD@976|Bacteroidetes,1I07B@117743|Flavobacteriia,3ZR5G@59732|Chryseobacterium	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
SRR25158343_k127_246708_301	1504672.669785508	6.748e-35	140.0	COG3230@1|root,COG3230@2|Bacteria,1N9VG@1224|Proteobacteria,2VVRM@28216|Betaproteobacteria,4AFXK@80864|Comamonadaceae	28216|Betaproteobacteria	P	Heme oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Heme_oxygenase
SRR25158343_k127_246708_190	313606.M23134_00440	3.966e-67	234.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158343_k127_246708_230	251229.Chro_5449	1.154e-53	194.0	COG0454@1|root,COG0454@2|Bacteria,1GR2B@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158343_k127_246708_327	1196323.ALKF01000203_gene3746	2.013e-31	130.0	COG3797@1|root,COG3797@2|Bacteria,1VJ1T@1239|Firmicutes,4HQ2E@91061|Bacilli,274WH@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158343_k127_246708_168	926549.KI421517_gene828	2.472e-76	261.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
SRR25158343_k127_246708_61	880071.Fleli_0540	1.934e-157	503.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158343_k127_246708_44	1313421.JHBV01000043_gene3012	5.761e-186	589.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158343_k127_246708_360	1121272.KB903249_gene2389	8.546e-22	106.0	COG3173@1|root,COG3173@2|Bacteria,2HH8W@201174|Actinobacteria,4DIM4@85008|Micromonosporales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
SRR25158343_k127_246708_197	221288.JH992901_gene5147	1.244e-63	222.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria,1JKN0@1189|Stigonemataceae	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SRR25158343_k127_246708_62	313606.M23134_00448	6.132e-157	506.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158343_k127_246708_107	1515613.HQ37_05955	3.481e-115	392.0	2C6VU@1|root,2Z7RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_274	269798.CHU_2091	2.168e-41	156.0	COG3012@1|root,COG3012@2|Bacteria,4NT83@976|Bacteroidetes,47RFN@768503|Cytophagia	976|Bacteroidetes	S	Preprotein translocase subunit SecA	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
SRR25158343_k127_246708_75	234267.Acid_2681	8.494e-146	470.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
SRR25158343_k127_246708_446	41431.PCC8801_3312	0.0001857	44.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,3KHH2@43988|Cyanothece	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158343_k127_246708_436	1120973.AQXL01000095_gene238	2.182e-05	49.0	COG0412@1|root,COG0412@2|Bacteria,1UZRU@1239|Firmicutes,4HEHA@91061|Bacilli,2785N@186823|Alicyclobacillaceae	91061|Bacilli	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158343_k127_246708_203	861299.J421_0970	2.699e-62	225.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	fes	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
SRR25158343_k127_246708_321	1101190.ARWB01000001_gene91	1.375e-32	143.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria,3700Q@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158343_k127_246708_287	1131269.AQVV01000025_gene2327	5.871e-38	164.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HTH_31
SRR25158343_k127_246708_218	357808.RoseRS_1519	2.326e-57	225.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,Pkinase
SRR25158343_k127_246708_26	215803.DB30_2893	7.152e-216	691.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YYTH@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	prlC1	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158343_k127_246708_118	313606.M23134_04461	6.885e-104	344.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,47JB0@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158343_k127_246708_172	1174528.JH992891_gene352	1.293e-74	259.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158343_k127_246708_328	1122223.KB890687_gene2590	4.281e-31	126.0	COG2050@1|root,COG2050@2|Bacteria,1WJS6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158343_k127_246708_82	1379270.AUXF01000004_gene3094	1.839e-139	464.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158343_k127_246708_405	234267.Acid_0548	2.194e-09	70.0	COG3307@1|root,COG3307@2|Bacteria,3Y88V@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158343_k127_246708_132	1232437.KL661987_gene326	1.155e-94	323.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2MKAM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158343_k127_246708_275	1267535.KB906767_gene3210	3.716e-41	175.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_246708_326	404589.Anae109_2606	1.336e-31	144.0	COG2244@1|root,COG2244@2|Bacteria,1P0EB@1224|Proteobacteria,431IR@68525|delta/epsilon subdivisions,2WW7D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158343_k127_246708_283	1123242.JH636434_gene4270	1.654e-38	161.0	COG1541@1|root,COG1541@2|Bacteria,2IZEM@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
SRR25158343_k127_246708_124	404380.Gbem_3444	1.812e-100	344.0	COG2006@1|root,COG2006@2|Bacteria,1NS70@1224|Proteobacteria,42Y7Z@68525|delta/epsilon subdivisions,2WTXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SRR25158343_k127_246708_399	882086.SacxiDRAFT_0073	6.319e-12	74.0	COG2230@1|root,COG2230@2|Bacteria,2I3H4@201174|Actinobacteria	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_246708_183	935863.AWZR01000003_gene2835	4.358e-70	252.0	2DBFX@1|root,2Z917@2|Bacteria,1P4PR@1224|Proteobacteria,1RWCW@1236|Gammaproteobacteria,1X36T@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_147	1121403.AUCV01000032_gene2914	3.362e-88	320.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,42SMC@68525|delta/epsilon subdivisions,2X5EG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
SRR25158343_k127_246708_272	269799.Gmet_2004	1.579e-41	168.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,43VBU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_246708_127	1267535.KB906767_gene2188	6.196e-99	336.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_246708_51	234267.Acid_0272	4.55e-169	552.0	COG0367@1|root,COG0367@2|Bacteria,3Y75N@57723|Acidobacteria	57723|Acidobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158343_k127_246708_76	1210884.HG799469_gene14188	1.71e-145	471.0	COG0438@1|root,COG0438@2|Bacteria,2J15Q@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158343_k127_246708_422	292459.STH640	3.299e-07	59.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158343_k127_246708_102	204669.Acid345_4396	3.318e-120	417.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_246708_411	1480694.DC28_09925	1.21e-08	61.0	COG0695@1|root,COG0695@2|Bacteria,2JAZC@203691|Spirochaetes	203691|Spirochaetes	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158343_k127_246708_331	266117.Rxyl_0743	1.794e-30	123.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158343_k127_246708_6	321332.CYB_1115	2.223e-320	999.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G0GP@1117|Cyanobacteria,1GYTG@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158343_k127_246708_37	1279009.ADICEAN_03089	1.102e-193	614.0	COG0612@1|root,COG0612@2|Bacteria,4NE0K@976|Bacteroidetes,47TKT@768503|Cytophagia	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_246708_68	861299.J421_0763	4.536e-153	497.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_246708_333	1519464.HY22_13530	4.136e-30	123.0	COG4712@1|root,COG4712@2|Bacteria	2|Bacteria	S	DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	DUF1071,Rad52_Rad22
SRR25158343_k127_246708_133	323261.Noc_0468	3.118e-94	325.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria,1WXGY@135613|Chromatiales	135613|Chromatiales	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158343_k127_246708_20	771875.Ferpe_2025	7.662e-230	722.0	COG1884@1|root,COG1884@2|Bacteria,2GBZM@200918|Thermotogae	200918|Thermotogae	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158343_k127_246708_384	870187.Thini_0083	1.203e-16	82.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,1SESI@1236|Gammaproteobacteria,463D1@72273|Thiotrichales	72273|Thiotrichales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR25158343_k127_246708_338	1382359.JIAL01000001_gene2570	3.431e-28	123.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria,2JJBC@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_198	436114.SYO3AOP1_0232	2.624e-63	232.0	COG2265@1|root,COG2265@2|Bacteria,2G3V7@200783|Aquificae	200783|Aquificae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
SRR25158343_k127_246708_277	1173022.Cri9333_3521	4.888e-41	154.0	COG0745@1|root,COG0745@2|Bacteria,1G76E@1117|Cyanobacteria,1HBQR@1150|Oscillatoriales	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158343_k127_246708_41	1173022.Cri9333_3522	1.791e-191	617.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1G26V@1117|Cyanobacteria,1HABC@1150|Oscillatoriales	1117|Cyanobacteria	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158343_k127_246708_240	1173022.Cri9333_3523	4.331e-50	184.0	COG0835@1|root,COG0835@2|Bacteria,1G7FI@1117|Cyanobacteria,1HBXN@1150|Oscillatoriales	1117|Cyanobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158343_k127_246708_34	1173028.ANKO01000214_gene6278	1.381e-203	656.0	COG0840@1|root,COG0840@2|Bacteria,1G4MY@1117|Cyanobacteria,1HA77@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRR25158343_k127_246708_54	1173028.ANKO01000214_gene6277	7.635e-167	546.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158343_k127_246708_139	56110.Oscil6304_4194	2.066e-92	311.0	COG1352@1|root,COG1352@2|Bacteria,1G4QS@1117|Cyanobacteria,1H8YH@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575,ko:K13486	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR25158343_k127_246708_87	1173028.ANKO01000214_gene6271	1.389e-133	434.0	COG2201@1|root,COG2201@2|Bacteria,1G2N5@1117|Cyanobacteria,1H741@1150|Oscillatoriales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158343_k127_246708_288	401526.TcarDRAFT_0869	1.315e-37	145.0	COG0745@1|root,COG0745@2|Bacteria	401526.TcarDRAFT_0869|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_189	56110.Oscil6304_3208	2.174e-67	235.0	COG1776@1|root,COG1776@2|Bacteria,1G9M7@1117|Cyanobacteria,1HHRB@1150|Oscillatoriales	1117|Cyanobacteria	NT	CheC inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
SRR25158343_k127_246708_99	1174528.JH992898_gene5117	8.664e-122	409.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	1174528.JH992898_gene5117|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_244	661367.LLO_3021	1.016e-48	188.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,1STBF@1236|Gammaproteobacteria,1JD5H@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_246708_216	1499967.BAYZ01000147_gene731	1.119e-57	213.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158343_k127_246708_351	72658.Bostr.23794s0725.1.p	6.445e-24	104.0	COG1324@1|root,KOG3338@2759|Eukaryota,37Q9K@33090|Viridiplantae,3GBI0@35493|Streptophyta,3HU5S@3699|Brassicales	35493|Streptophyta	P	CutA1 divalent ion tolerance protein	-	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158343_k127_246708_220	1267535.KB906767_gene4484	6.148e-57	202.0	293T3@1|root,2ZR8H@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
SRR25158343_k127_246708_324	345219.Bcoa_2029	4.008e-32	125.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,1ZHUY@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SRR25158343_k127_246708_425	756067.MicvaDRAFT_2573	7.176e-07	53.0	COG4194@1|root,COG4194@2|Bacteria,1G8KT@1117|Cyanobacteria,1HCI5@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
SRR25158343_k127_246708_157	861299.J421_0058	2.4e-84	287.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158343_k127_246708_143	1382359.JIAL01000001_gene1578	1.082e-90	304.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158343_k127_246708_286	682795.AciX8_3255	3.189e-38	165.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158343_k127_246708_445	667014.Thein_0942	0.0001851	48.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,2GIQQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
SRR25158343_k127_246708_246	204669.Acid345_2226	2.173e-48	184.0	COG0457@1|root,COG0457@2|Bacteria,3Y893@57723|Acidobacteria,2JNSA@204432|Acidobacteriia	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_303193_1	580327.Tthe_1687	5.268e-13	71.0	COG2963@1|root,COG2963@2|Bacteria,1VEWG@1239|Firmicutes,24QQZ@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158343_k127_303193_0	1166018.FAES_pFAES01008	1.638e-76	267.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,47MKZ@768503|Cytophagia	976|Bacteroidetes	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158343_k127_306309_6	491915.Aflv_1240	9.867e-155	497.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli,21VZV@150247|Anoxybacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_306309_13	641107.CDLVIII_5234	3.14e-71	256.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,36E4B@31979|Clostridiaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158343_k127_306309_20	194439.CT1330	1.113e-42	161.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,1FDMF@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaC
SRR25158343_k127_306309_22	1303518.CCALI_02289	1.483e-29	128.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
SRR25158343_k127_306309_16	56780.SYN_03169	1.477e-57	210.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2WSHT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158343_k127_306309_26	1198114.AciX9_2169	3.999e-15	82.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_306309_18	264462.Bd3503	4.66e-48	183.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WR0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158343_k127_306309_19	1227739.Hsw_2994	8.966e-48	182.0	COG5429@1|root,COG5429@2|Bacteria,4NNGV@976|Bacteroidetes,47RAT@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
SRR25158343_k127_306309_0	204669.Acid345_2022	0.0	1115.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158343_k127_306309_25	68170.KL590535_gene3759	2.822e-16	85.0	COG5401@1|root,COG5401@2|Bacteria,2H4HT@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158343_k127_306309_27	1410653.JHVC01000014_gene3381	2.431e-13	74.0	2E6RA@1|root,32P0C@2|Bacteria,1UPZJ@1239|Firmicutes,24S9G@186801|Clostridia,36NDX@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2695
SRR25158343_k127_306309_9	1121272.KB903293_gene7328	5.486e-121	401.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria,4DCIJ@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158343_k127_306309_29	278963.ATWD01000001_gene3853	3.245e-05	53.0	COG2825@1|root,COG2825@2|Bacteria,3Y4WC@57723|Acidobacteria,2JJHF@204432|Acidobacteriia	204432|Acidobacteriia	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158343_k127_306309_4	1121382.JQKG01000017_gene1804	2.812e-176	564.0	COG1488@1|root,COG1488@2|Bacteria,1WM9C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	2.4.2.12	ko:K03462	ko00760,ko01100,ko04621,map00760,map01100,map04621	-	R01271	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158343_k127_306309_14	358681.BBR47_15260	8.323e-69	243.0	COG4295@1|root,COG4295@2|Bacteria,1TSFT@1239|Firmicutes,4HGDA@91061|Bacilli,26QRJ@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2263
SRR25158343_k127_306309_11	1121904.ARBP01000004_gene925	5.025e-97	332.0	COG3386@1|root,COG3386@2|Bacteria,4PKKP@976|Bacteroidetes,47RQ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158343_k127_306309_12	195250.CM001776_gene3096	3.559e-91	312.0	COG1051@1|root,COG1056@1|root,COG1051@2|Bacteria,COG1056@2|Bacteria,1G1NY@1117|Cyanobacteria,1H02C@1129|Synechococcus	1117|Cyanobacteria	FH	Cytidylyltransferase-like	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.7.7.1	ko:K13522	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NUDIX
SRR25158343_k127_306309_28	1410632.JHWW01000020_gene364	1.402e-08	67.0	2DUUF@1|root,33SB4@2|Bacteria,1V7YB@1239|Firmicutes,24MDM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_306309_10	1469245.JFBG01000027_gene1490	1.011e-103	353.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158343_k127_306309_15	234267.Acid_1127	9.625e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_306309_7	1183438.GKIL_3395	1.249e-151	511.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_306309_3	1303518.CCALI_00899	2.339e-176	565.0	COG0423@1|root,COG0423@2|Bacteria	2|Bacteria	J	glycyl-tRNA aminoacylation	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
SRR25158343_k127_306309_5	335659.S23_05140	3.942e-170	546.0	COG1787@1|root,COG1787@2|Bacteria,1NEPX@1224|Proteobacteria,2UFBH@28211|Alphaproteobacteria,3K37W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_306309_31	436308.Nmar_1073	0.0001189	52.0	COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea	2157|Archaea	C	LamG domain protein jellyroll fold domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	Copper-bind,GSDH,Laminin_G_3,ThuA,fn3
SRR25158343_k127_306309_17	314278.NB231_14333	3.546e-56	202.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria,1S6QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158343_k127_306309_1	411684.HPDFL43_20137	2.404e-232	738.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,43IV8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158343_k127_306309_23	1128421.JAGA01000002_gene576	2.649e-28	115.0	COG0184@1|root,COG0184@2|Bacteria,2NPTZ@2323|unclassified Bacteria	2|Bacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158343_k127_306309_2	1144275.COCOR_06267	2.554e-189	601.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158343_k127_306309_21	1274374.CBLK010000053_gene2206	2.014e-37	148.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,26XI3@186822|Paenibacillaceae	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158343_k127_306309_24	177416.FTT_0351	1.854e-27	117.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,460U0@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158343_k127_306309_8	682795.AciX8_1027	1.198e-139	451.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158343_k127_320997_0	195250.CM001776_gene1195	4.786e-243	784.0	COG4644@1|root,COG4644@2|Bacteria,1G1DD@1117|Cyanobacteria,1H2YR@1129|Synechococcus	1117|Cyanobacteria	L	L COG4644 Transposase and inactivated derivatives, TnpA family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
SRR25158343_k127_320997_1	1313421.JHBV01000143_gene1158	5.226e-86	289.0	COG1961@1|root,COG1961@2|Bacteria,4NJM8@976|Bacteroidetes,1ITQV@117747|Sphingobacteriia	976|Bacteroidetes	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR25158343_k127_320997_2	1191523.MROS_2208	5.59e-83	303.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	irp	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158343_k127_320997_3	1444711.CCJF01000005_gene854	2.124e-07	53.0	COG2217@1|root,COG2217@2|Bacteria,2JFNZ@204428|Chlamydiae	204428|Chlamydiae	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
SRR25158343_k127_501038_3	941824.TCEL_00205	1.619e-156	507.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,36EAU@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158343_k127_501038_19	234267.Acid_3868	4.33e-71	245.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158343_k127_501038_21	1540221.JQNI01000004_gene99	1.244e-66	234.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158343_k127_501038_11	204669.Acid345_0924	8.217e-93	308.0	COG0378@1|root,COG0378@2|Bacteria,3Y3AD@57723|Acidobacteria,2JJ75@204432|Acidobacteriia	204432|Acidobacteriia	KO	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
SRR25158343_k127_501038_30	1267533.KB906737_gene1742	1.573e-31	126.0	COG0375@1|root,COG0375@2|Bacteria,3Y5WA@57723|Acidobacteria,2JK5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
SRR25158343_k127_501038_35	237368.SCABRO_03527	8.333e-19	93.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158343_k127_501038_34	401053.AciPR4_3838	3.233e-20	99.0	COG3477@1|root,COG3477@2|Bacteria,3Y8IX@57723|Acidobacteria,2JNGH@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1440
SRR25158343_k127_501038_25	743836.AYNA01000096_gene1975	2.013e-43	165.0	COG0680@1|root,COG0680@2|Bacteria,1N48F@1224|Proteobacteria	1224|Proteobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158343_k127_501038_31	479434.Sthe_2493	4.236e-31	124.0	COG0680@1|root,COG0680@2|Bacteria,2G86Z@200795|Chloroflexi,27YUD@189775|Thermomicrobia	189775|Thermomicrobia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_501038_12	1267533.KB906737_gene1734	7.255e-90	307.0	2DBQJ@1|root,2ZAF2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_501038_17	886293.Sinac_4496	5.226e-74	254.0	29Z4R@1|root,30M2D@2|Bacteria,2J2SH@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_501038_20	682795.AciX8_4217	9.748e-69	239.0	2ADVU@1|root,313MT@2|Bacteria,3Y7R2@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_501038_28	886293.Sinac_4494	1.252e-33	137.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	NifU,Rieske
SRR25158343_k127_501038_0	1267533.KB906737_gene1730	0.0	1062.0	COG0374@1|root,COG0374@2|Bacteria,3Y3C2@57723|Acidobacteria,2JJUU@204432|Acidobacteriia	204432|Acidobacteriia	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SRR25158343_k127_501038_1	682795.AciX8_4213	7.263e-213	663.0	COG1740@1|root,COG1740@2|Bacteria,3Y3HS@57723|Acidobacteria,2JJYD@204432|Acidobacteriia	204432|Acidobacteriia	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
SRR25158343_k127_501038_26	1267535.KB906767_gene4012	8.161e-38	148.0	COG3477@1|root,COG3477@2|Bacteria,3Y7QZ@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1440)	-	-	-	ko:K08996	-	-	-	-	ko00000	-	-	-	DUF1440
SRR25158343_k127_501038_8	1519464.HY22_08540	7.671e-107	354.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158343_k127_501038_15	1410653.JHVC01000003_gene3916	1.353e-83	292.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,36DRS@31979|Clostridiaceae	186801|Clostridia	M	Peptidase, S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158343_k127_501038_5	1469557.JSWF01000014_gene2626	7.718e-140	454.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1HZRM@117743|Flavobacteriia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
SRR25158343_k127_501038_9	204669.Acid345_2087	1.335e-103	344.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
SRR25158343_k127_501038_14	864073.HFRIS_013299	2.212e-84	289.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VZ36@28216|Betaproteobacteria,472UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158343_k127_501038_10	448385.sce9293	5.247e-96	321.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria	1224|Proteobacteria	S	phosphohydrolases	cpdA	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158343_k127_501038_4	192952.MM_3198	5.889e-147	479.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
SRR25158343_k127_501038_27	382464.ABSI01000020_gene223	9.349e-34	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_501038_24	452637.Oter_3517	2.03e-61	229.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158343_k127_501038_6	63577.G9NQK4	1.154e-139	450.0	COG1087@1|root,KOG1371@2759|Eukaryota,39KCQ@33154|Opisthokonta,3PBHS@4751|Fungi,3RN10@4890|Ascomycota	4751|Fungi	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SRR25158343_k127_501038_22	682795.AciX8_3399	4.23e-65	233.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158343_k127_501038_23	765420.OSCT_1167	3.3e-64	225.0	COG4636@1|root,COG4636@2|Bacteria,2G9UV@200795|Chloroflexi,37786@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158343_k127_501038_36	317936.Nos7107_1630	1.405e-18	93.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Cu_amine_oxidN1
SRR25158343_k127_501038_7	682795.AciX8_3319	7.116e-116	384.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria,2JITB@204432|Acidobacteriia	204432|Acidobacteriia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158343_k127_501038_16	1396141.BATP01000009_gene2656	3.116e-80	274.0	COG3361@1|root,COG3361@2|Bacteria,46X33@74201|Verrucomicrobia,2IUDI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
SRR25158343_k127_501038_13	234267.Acid_1310	1.384e-85	292.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria	57723|Acidobacteria	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158343_k127_501038_2	1267535.KB906767_gene1169	1.223e-165	535.0	COG1502@1|root,COG1502@2|Bacteria,3Y2GD@57723|Acidobacteria	57723|Acidobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158343_k127_501038_18	204669.Acid345_0496	2.547e-73	258.0	COG3568@1|root,COG3568@2|Bacteria,3Y4HM@57723|Acidobacteria,2JKST@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158343_k127_501038_32	32057.KB217478_gene452	1.01e-28	121.0	COG2389@1|root,COG2389@2|Bacteria,1G6XV@1117|Cyanobacteria,1HKET@1161|Nostocales	1117|Cyanobacteria	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2227
SRR25158343_k127_501038_33	335543.Sfum_0069	8.101e-22	109.0	COG1357@1|root,COG2201@1|root,COG1357@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K18876	ko02020,ko02030,ko04626,map02020,map02030,map04626	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,DDE_5,Response_reg,TAL_effector
SRR25158343_k127_501038_37	457396.CSBG_00374	7.407e-09	57.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,36FEX@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpA2	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158343_k127_504010_1	903818.KI912268_gene3150	4.935e-221	701.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158343_k127_504010_3	204669.Acid345_1391	2.017e-171	546.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158343_k127_504010_13	903818.KI912268_gene3152	1.977e-116	387.0	COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
SRR25158343_k127_504010_29	525904.Tter_0360	2.303e-60	232.0	COG5427@1|root,COG5427@2|Bacteria	2|Bacteria	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_504010_50	497964.CfE428DRAFT_4456	1.216e-23	117.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_504010_66	28444.JODQ01000008_gene1147	0.0002104	48.0	2C9IE@1|root,31AT3@2|Bacteria,2IM6M@201174|Actinobacteria,4EJKC@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158343_k127_504010_56	218491.ECA2896	3.301e-14	74.0	arCOG12966@1|root,3325K@2|Bacteria,1N9AA@1224|Proteobacteria,1SDN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_504010_2	926550.CLDAP_38340	3.799e-175	565.0	COG0433@1|root,COG0433@2|Bacteria,2G78T@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
SRR25158343_k127_504010_32	886293.Sinac_4049	2.161e-54	196.0	COG0783@1|root,COG0783@2|Bacteria,2IZJP@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR25158343_k127_504010_17	1301100.HG529422_gene4234	3.455e-103	347.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,36DHM@31979|Clostridiaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158343_k127_504010_45	1121289.JHVL01000041_gene3051	4.221e-31	132.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,36IPK@31979|Clostridiaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
SRR25158343_k127_504010_53	1379858.N508_01750	1.844e-18	89.0	COG1734@1|root,COG1734@2|Bacteria,2GFP6@200930|Deferribacteres	200930|Deferribacteres	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158343_k127_504010_43	1347087.CBYO010000020_gene2972	3.63e-32	132.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli	91061|Bacilli	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158343_k127_504010_44	204669.Acid345_0022	3.258e-31	127.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria,2JJ9Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158343_k127_504010_38	1286171.EAL2_c11660	5.159e-34	139.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,25WQX@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158343_k127_504010_9	234267.Acid_3160	3.043e-131	427.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR25158343_k127_504010_39	373994.Riv7116_4537	5.381e-34	132.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HNYF@1161|Nostocales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158343_k127_504010_48	1158318.ATXC01000002_gene1585	1.509e-24	107.0	COG0261@1|root,COG0261@2|Bacteria,2G4AY@200783|Aquificae	200783|Aquificae	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158343_k127_504010_35	379066.GAU_2588	1.669e-41	158.0	COG1853@1|root,COG1853@2|Bacteria,1ZTVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158343_k127_504010_22	1267535.KB906767_gene4165	2.527e-82	283.0	COG0142@1|root,COG0142@2|Bacteria,3Y2HS@57723|Acidobacteria,2JIPK@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158343_k127_504010_23	1163617.SCD_n01348	4.285e-80	287.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VHWW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	eight transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
SRR25158343_k127_504010_26	933262.AXAM01000034_gene1565	2.724e-67	256.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
SRR25158343_k127_504010_37	401053.AciPR4_0585	1.085e-34	151.0	COG3206@1|root,COG3206@2|Bacteria,3Y3JI@57723|Acidobacteria,2JI13@204432|Acidobacteriia	204432|Acidobacteriia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
SRR25158343_k127_504010_30	639030.JHVA01000001_gene3247	3.585e-60	221.0	COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria,2JKNX@204432|Acidobacteriia	204432|Acidobacteriia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR25158343_k127_504010_36	1125863.JAFN01000001_gene472	1.242e-38	158.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,42QS3@68525|delta/epsilon subdivisions,2WMX0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Capsular exopolysaccharide family	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,ParA
SRR25158343_k127_504010_16	1125863.JAFN01000001_gene473	4.944e-104	354.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158343_k127_504010_47	1121441.AUCX01000008_gene2153	3.089e-25	116.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42SP0@68525|delta/epsilon subdivisions,2WNYF@28221|Deltaproteobacteria,2MAXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158343_k127_504010_41	945713.IALB_2314	7.735e-33	140.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158343_k127_504010_51	1444712.BN1013_00784	3.288e-19	100.0	COG0582@1|root,COG0582@2|Bacteria,2JG7E@204428|Chlamydiae	204428|Chlamydiae	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158343_k127_504010_61	1047013.AQSP01000118_gene1263	1.431e-07	60.0	COG0817@1|root,COG0817@2|Bacteria	2|Bacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158343_k127_504010_14	391626.OAN307_c31540	1.599e-113	384.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158343_k127_504010_15	592029.DDD_0686	1.254e-104	357.0	COG1746@1|root,COG1746@2|Bacteria	2|Bacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158343_k127_504010_12	941639.BCO26_0358	2.544e-121	400.0	COG1403@1|root,COG1403@2|Bacteria,1V68V@1239|Firmicutes	1239|Firmicutes	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_504010_24	1122173.AXVL01000018_gene452	2.26e-77	271.0	COG0863@1|root,COG0863@2|Bacteria,37A63@32066|Fusobacteria	32066|Fusobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158343_k127_504010_58	65393.PCC7424_3207	1.716e-08	58.0	COG3668@1|root,COG3668@2|Bacteria,1G90A@1117|Cyanobacteria,3KKKY@43988|Cyanothece	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158343_k127_504010_11	402881.Plav_0314	1.584e-125	413.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,2U47U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
SRR25158343_k127_504010_25	234267.Acid_2524	2.666e-76	269.0	2E0FE@1|root,32W1M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
SRR25158343_k127_504010_19	204669.Acid345_4390	1.302e-94	345.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
SRR25158343_k127_504010_31	1183438.GKIL_3396	4.889e-55	199.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
SRR25158343_k127_504010_60	1463853.JOHW01000039_gene5337	4.765e-08	63.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158343_k127_504010_62	1123399.AQVE01000007_gene1058	1.726e-07	64.0	COG3063@1|root,COG3063@2|Bacteria,1R1T7@1224|Proteobacteria,1S64D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_504010_34	682795.AciX8_1493	2.283e-44	179.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158343_k127_504010_49	1121396.KB893096_gene3543	1.887e-24	116.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42QGU@68525|delta/epsilon subdivisions,2WMBM@28221|Deltaproteobacteria,2MI32@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158343_k127_504010_21	682795.AciX8_1492	7.262e-89	322.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	57723|Acidobacteria	D	G-rich domain on putative tyrosine kinase	-	-	2.7.10.1	ko:K08252,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
SRR25158343_k127_504010_5	1122927.KB895417_gene3169	1.172e-149	496.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,276H6@186822|Paenibacillaceae	91061|Bacilli	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158343_k127_504010_65	1524467.IV04_21350	0.0001727	48.0	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria,402YH@613|Serratia	1236|Gammaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	ybcI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158343_k127_504010_27	1232437.KL661988_gene156	1.131e-63	224.0	COG0500@1|root,COG2226@2|Bacteria,1RG8C@1224|Proteobacteria,42ZN1@68525|delta/epsilon subdivisions,2WV4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_504010_46	391009.Tmel_0361	1.396e-30	136.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158343_k127_504010_42	1123057.P872_13745	3.495e-32	141.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158343_k127_504010_54	1121012.AUKX01000058_gene1355	1.181e-16	93.0	2ACRJ@1|root,312CA@2|Bacteria,4NNY3@976|Bacteroidetes,1I6D8@117743|Flavobacteriia	976|Bacteroidetes	S	EpsG family	-	-	-	-	-	-	-	-	-	-	-	-	EpsG
SRR25158343_k127_504010_8	1121288.AULL01000002_gene2111	3.513e-135	438.0	COG0189@1|root,COG0189@2|Bacteria,4NHYZ@976|Bacteroidetes,1IN97@117743|Flavobacteriia,3ZTVA@59732|Chryseobacterium	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158343_k127_504010_6	620914.JH621250_gene2212	1.852e-148	479.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,1HXBG@117743|Flavobacteriia,2YIQP@290174|Aquimarina	976|Bacteroidetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
SRR25158343_k127_504010_10	338966.Ppro_2450	3.261e-128	420.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,43S9C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158343_k127_504010_20	992406.RIA_1504	3.198e-94	312.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,1HWQ3@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	wcgN	-	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
SRR25158343_k127_504010_7	883096.HMPREF9699_01729	6.96e-143	459.0	COG0189@1|root,COG0189@2|Bacteria,4NHX0@976|Bacteroidetes,1IJ8Z@117743|Flavobacteriia	976|Bacteroidetes	HJ	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
SRR25158343_k127_504010_28	873517.HMPREF1977_1693	1.616e-63	224.0	COG1011@1|root,COG1011@2|Bacteria,4NQJ0@976|Bacteroidetes,1I1I6@117743|Flavobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158343_k127_504010_63	1451189.CFAL_07725	2.703e-07	55.0	COG2963@1|root,COG2963@2|Bacteria,2HGWI@201174|Actinobacteria,22PPS@1653|Corynebacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
SRR25158343_k127_504010_40	1166018.FAES_pFAES01008	5.881e-34	137.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,47MKZ@768503|Cytophagia	976|Bacteroidetes	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158343_k127_504010_52	153948.NAL212_2524	3.733e-19	91.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,37275@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158343_k127_504010_33	391603.FBALC1_05468	1.762e-47	180.0	COG2242@1|root,COG2242@2|Bacteria,4PMEA@976|Bacteroidetes,1I6FQ@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158343_k127_504010_4	1296415.JACC01000002_gene3257	1.272e-168	537.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia,2YIT9@290174|Aquimarina	976|Bacteroidetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158343_k127_504010_55	443144.GM21_0901	7.404e-16	82.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	algA	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,FdtA,MannoseP_isomer,NTP_transferase
SRR25158343_k127_504010_18	485916.Dtox_2855	1.225e-102	346.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,261N7@186807|Peptococcaceae	186801|Clostridia	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R02984,R05176	RC00289,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158343_k127_504010_0	671143.DAMO_1991	1.015e-235	745.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
SRR25158343_k127_504010_59	457396.CSBG_00374	2.047e-08	56.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,36FEX@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wbpA2	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158343_k127_517765_0	309807.SRU_0853	2.261e-61	222.0	COG3039@1|root,COG3039@2|Bacteria,4PM5N@976|Bacteroidetes	2|Bacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
SRR25158343_k127_633810_53	234267.Acid_5431	1.216e-136	458.0	COG1629@1|root,COG4771@2|Bacteria,3Y2GB@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_633810_220	397948.Cmaq_0211	1.998e-48	185.0	COG0492@1|root,arCOG01296@2157|Archaea,2XPQC@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_633810_252	1121403.AUCV01000069_gene2317	2.779e-34	153.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
SRR25158343_k127_633810_324	760154.Sulba_2107	1.497e-12	75.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42TN2@68525|delta/epsilon subdivisions,2YT3Y@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158343_k127_633810_327	1348114.OM33_20145	5.902e-11	75.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2PZG1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
SRR25158343_k127_633810_115	575540.Isop_3689	3.043e-93	324.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,2IXQA@203682|Planctomycetes	203682|Planctomycetes	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Globin,HAMP,MCPsignal,PAS_3,PAS_4,PAS_9
SRR25158343_k127_633810_44	575540.Isop_3690	2.02e-151	513.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,2IWWG@203682|Planctomycetes	203682|Planctomycetes	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158343_k127_633810_283	504472.Slin_0027	2.552e-24	115.0	COG0657@1|root,COG2755@1|root,COG0657@2|Bacteria,COG2755@2|Bacteria,4NNWF@976|Bacteroidetes,47RDI@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,Lipase_GDSL_2,Peptidase_S9
SRR25158343_k127_633810_172	649638.Trad_2700	1.016e-63	227.0	COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_633810_351	56107.Cylst_5059	2.773e-06	59.0	28K7X@1|root,2Z9VW@2|Bacteria,1G4E1@1117|Cyanobacteria,1HK48@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_330	163908.KB235896_gene1806	8.046e-11	73.0	28K7X@1|root,2Z9VW@2|Bacteria,1G4E1@1117|Cyanobacteria,1HK48@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_369	1469607.KK073768_gene2659	0.0004463	51.0	28K7X@1|root,2Z9VW@2|Bacteria,1G4E1@1117|Cyanobacteria,1HK48@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_60	443254.Marpi_1268	6.698e-134	442.0	COG0064@1|root,COG0064@2|Bacteria,2GCBS@200918|Thermotogae	200918|Thermotogae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158343_k127_633810_152	204669.Acid345_4431	3.215e-75	263.0	COG0265@1|root,COG0265@2|Bacteria,3Y99F@57723|Acidobacteria,2JJ0S@204432|Acidobacteriia	204432|Acidobacteriia	O	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SRR25158343_k127_633810_63	1267535.KB906767_gene3137	1.326e-132	452.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158343_k127_633810_192	933262.AXAM01000086_gene2640	1.693e-56	206.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria,2MIT5@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158343_k127_633810_167	926561.KB900617_gene1663	2.772e-67	240.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WAHZ@53433|Halanaerobiales	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158343_k127_633810_191	555079.Toce_1426	9.238e-57	210.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,42FIR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158343_k127_633810_30	111780.Sta7437_4128	8.352e-165	529.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria,3VI4W@52604|Pleurocapsales	1117|Cyanobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
SRR25158343_k127_633810_282	1340493.JNIF01000003_gene2460	2.365e-24	117.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_633810_284	1267534.KB906756_gene313	2.85e-24	117.0	COG2304@1|root,COG2304@2|Bacteria,3Y6C6@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SRR25158343_k127_633810_197	1211035.CD30_18750	2.393e-54	205.0	COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3IY7Y@400634|Lysinibacillus	91061|Bacilli	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_633810_151	330214.NIDE3038	2.421e-75	264.0	COG0673@1|root,COG0673@2|Bacteria,3J0M7@40117|Nitrospirae	40117|Nitrospirae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158343_k127_633810_195	204669.Acid345_4212	2.181e-55	213.0	COG1807@1|root,COG1807@2|Bacteria,3Y2K3@57723|Acidobacteria,2JHZC@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_633810_148	204669.Acid345_1160	1.083e-76	265.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158343_k127_633810_325	1121920.AUAU01000002_gene2002	3.18e-11	67.0	2CDNF@1|root,2ZTQP@2|Bacteria,3Y955@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_37	1183438.GKIL_3395	1.848e-156	523.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_633810_45	1267533.KB906733_gene3429	2.614e-150	481.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158343_k127_633810_345	1051501.AYTL01000030_gene3156	1.389e-07	53.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_10	243231.GSU2350	8.039e-233	737.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158343_k127_633810_146	1278073.MYSTI_06260	1.387e-77	276.0	COG2866@1|root,COG2866@2|Bacteria,1R6VU@1224|Proteobacteria	1224|Proteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158343_k127_633810_301	204669.Acid345_2988	3.143e-19	94.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158343_k127_633810_113	1382305.AZUC01000063_gene3363	3.092e-96	322.0	COG2321@1|root,COG2321@2|Bacteria,1TQKF@1239|Firmicutes,4HB7I@91061|Bacilli,26E8G@186818|Planococcaceae	91061|Bacilli	S	Putative neutral zinc metallopeptidase	XK27_03670	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158343_k127_633810_116	1121904.ARBP01000007_gene3016	3.921e-93	317.0	COG0596@1|root,COG0596@2|Bacteria,4NIQH@976|Bacteroidetes,47MKK@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158343_k127_633810_266	234267.Acid_5168	2.566e-31	125.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria	57723|Acidobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158343_k127_633810_209	1047013.AQSP01000137_gene553	1.831e-51	196.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158343_k127_633810_320	1217710.F969_01048	1.466e-14	76.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SEPS@1236|Gammaproteobacteria,3NPSB@468|Moraxellaceae	1236|Gammaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
SRR25158343_k127_633810_103	861299.J421_3940	3.15e-107	361.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
SRR25158343_k127_633810_257	118168.MC7420_5387	1.203e-32	131.0	COG0780@1|root,COG0780@2|Bacteria,1G5W6@1117|Cyanobacteria,1HB47@1150|Oscillatoriales	1117|Cyanobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158343_k127_633810_277	204669.Acid345_0553	1.957e-26	116.0	COG1329@1|root,COG1329@2|Bacteria,3Y4ZG@57723|Acidobacteria,2JMXA@204432|Acidobacteriia	204432|Acidobacteriia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158343_k127_633810_254	335543.Sfum_0084	9.379e-34	137.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158343_k127_633810_92	267608.RSc0539	1.666e-113	379.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1K3N3@119060|Burkholderiaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158343_k127_633810_337	378806.STAUR_4216	2.355e-09	63.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_9	234267.Acid_5526	3.88e-235	738.0	COG1032@1|root,COG1032@2|Bacteria,3Y2NI@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158343_k127_633810_321	215803.DB30_0786	3.682e-13	75.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,42SJ2@68525|delta/epsilon subdivisions,2WPC9@28221|Deltaproteobacteria,2Z01N@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K07773	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158343_k127_633810_67	401053.AciPR4_1374	1.72e-129	421.0	COG0535@1|root,COG0535@2|Bacteria,3Y3TY@57723|Acidobacteria,2JHZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158343_k127_633810_164	645991.Sgly_0136	8.306e-68	244.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158343_k127_633810_207	1336245.JAGO01000013_gene1642	3.392e-52	194.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XHIV@135619|Oceanospirillales	135619|Oceanospirillales	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_633810_234	1242864.D187_004633	5.987e-41	159.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria,2YV5C@29|Myxococcales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158343_k127_633810_247	1191523.MROS_1520	3.435e-37	145.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158343_k127_633810_85	1142394.PSMK_05030	1.974e-117	384.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
SRR25158343_k127_633810_215	1142394.PSMK_05040	4.247e-50	185.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_633810_212	562970.Btus_1758	1.318e-50	187.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,2789X@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158343_k127_633810_228	1123399.AQVE01000001_gene736	1.206e-44	170.0	2DQHJ@1|root,336X1@2|Bacteria,1QYDU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_141	264462.Bd3186	2.816e-79	272.0	COG0500@1|root,COG0500@2|Bacteria,1QY2M@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_633810_101	880073.Calab_1597	2.451e-109	360.0	COG2107@1|root,COG2107@2|Bacteria,2NQC0@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158343_k127_633810_222	234267.Acid_5311	3.593e-47	180.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_255	1382359.JIAL01000001_gene1609	2.135e-33	139.0	COG0204@1|root,COG0204@2|Bacteria,3Y49D@57723|Acidobacteria,2JJ6K@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158343_k127_633810_21	886293.Sinac_6154	4.328e-174	573.0	COG2866@1|root,COG2866@2|Bacteria,2IXPH@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158343_k127_633810_98	1173026.Glo7428_2179	7.788e-110	362.0	COG4294@1|root,COG4294@2|Bacteria,1G10X@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
SRR25158343_k127_633810_294	1347368.HG964404_gene5488	7.085e-21	99.0	2CA9Z@1|root,32ZYB@2|Bacteria	2|Bacteria	S	SMI1-KNR4 cell-wall	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4,SUKH_6
SRR25158343_k127_633810_130	1238182.C882_0401	2.894e-86	298.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VFY5@28211|Alphaproteobacteria,2JRKP@204441|Rhodospirillales	204441|Rhodospirillales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158343_k127_633810_76	395493.BegalDRAFT_0132	5.703e-122	407.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
SRR25158343_k127_633810_288	102129.Lepto7375DRAFT_0021	2.089e-23	117.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,1FZVW@1117|Cyanobacteria,1H8VD@1150|Oscillatoriales	1117|Cyanobacteria	T	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
SRR25158343_k127_633810_308	251221.35210810	5.781e-18	99.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_193	903818.KI912268_gene674	2.454e-56	223.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
SRR25158343_k127_633810_166	314275.MADE_1011875	1.482e-67	238.0	arCOG14015@1|root,30H02@2|Bacteria,1R3JD@1224|Proteobacteria,1S3GD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_62	1163408.UU9_07109	7.412e-133	432.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria	1224|Proteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158343_k127_633810_223	450851.PHZ_c0831	7.894e-47	177.0	COG4977@1|root,COG4977@2|Bacteria,1PFG6@1224|Proteobacteria,2V7GC@28211|Alphaproteobacteria,2KJ6G@204458|Caulobacterales	204458|Caulobacterales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158343_k127_633810_51	518766.Rmar_0546	1.2e-139	465.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1FKC5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158343_k127_633810_230	886293.Sinac_3762	3.405e-44	171.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,2IZ1I@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
SRR25158343_k127_633810_251	1239962.C943_03877	7.691e-35	145.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158343_k127_633810_253	1499967.BAYZ01000090_gene4936	7.493e-34	142.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158343_k127_633810_0	929556.Solca_2801	0.0	1204.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IPRD@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
SRR25158343_k127_633810_280	243231.GSU3495	7.973e-25	107.0	2E7B6@1|root,331UK@2|Bacteria,1N80C@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_162	269799.Gmet_2052	1.686e-68	246.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158343_k127_633810_300	204669.Acid345_4341	1.223e-19	90.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria,2JJSQ@204432|Acidobacteriia	204432|Acidobacteriia	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
SRR25158343_k127_633810_216	1348338.ADILRU_1342	8.665e-50	185.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4FMR0@85023|Microbacteriaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
SRR25158343_k127_633810_206	338963.Pcar_1692	1.46e-52	198.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43RXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158343_k127_633810_355	234267.Acid_4474	2.943e-05	54.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158343_k127_633810_336	1340493.JNIF01000003_gene1849	2.275e-09	67.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158343_k127_633810_303	1968.JOEV01000046_gene2342	4.51e-19	92.0	2E37T@1|root,32Y7G@2|Bacteria,2GQH5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158343_k127_633810_23	1380384.JADN01000007_gene1616	1.959e-172	551.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158343_k127_633810_88	485918.Cpin_1817	3.69e-116	380.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158343_k127_633810_332	251229.Chro_4009	4.544e-10	72.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SRR25158343_k127_633810_126	330214.NIDE3564	4.484e-87	322.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
SRR25158343_k127_633810_318	709032.Sulku_1940	1.264e-14	86.0	COG0457@1|root,COG0457@2|Bacteria,1PGQM@1224|Proteobacteria,433NE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_333	1174684.EBMC1_01665	7.007e-10	67.0	2BUWS@1|root,32Q8X@2|Bacteria,1P2PU@1224|Proteobacteria,2UV5V@28211|Alphaproteobacteria,2KBCD@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_231	575540.Isop_1666	9.767e-44	181.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
SRR25158343_k127_633810_121	83219.PM02_05110	2.154e-90	309.0	COG0662@1|root,COG1917@1|root,COG0662@2|Bacteria,COG1917@2|Bacteria,1NNBT@1224|Proteobacteria,2U1PR@28211|Alphaproteobacteria,3ZVCJ@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_633810_238	1242864.D187_004067	3.104e-40	160.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YWZJ@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4
SRR25158343_k127_633810_260	234267.Acid_4894	2.652e-32	132.0	COG2365@1|root,COG2365@2|Bacteria,3Y8BW@57723|Acidobacteria	57723|Acidobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
SRR25158343_k127_633810_198	204669.Acid345_4703	3.3e-54	196.0	COG2318@1|root,COG2318@2|Bacteria,3Y4AI@57723|Acidobacteria,2JKRK@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SRR25158343_k127_633810_79	926561.KB900623_gene1074	4.002e-121	400.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WB5Z@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158343_k127_633810_177	204669.Acid345_1420	1.107e-61	229.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria,2JI1B@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158343_k127_633810_71	485916.Dtox_3202	7.844e-127	415.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,260R0@186807|Peptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRR25158343_k127_633810_56	468059.AUHA01000004_gene2288	2.371e-135	439.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1IQ0J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_633810_28	946077.W5A_11881	5.805e-166	529.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
SRR25158343_k127_633810_142	269798.CHU_1271	4.583e-79	268.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,47P9A@768503|Cytophagia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158343_k127_633810_133	742766.HMPREF9455_00099	5.526e-85	287.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,2FMBX@200643|Bacteroidia,22WHU@171551|Porphyromonadaceae	976|Bacteroidetes	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158343_k127_633810_97	694427.Palpr_1159	6.756e-110	360.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,2FNY2@200643|Bacteroidia,22WRH@171551|Porphyromonadaceae	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158343_k127_633810_145	485918.Cpin_1832	8.887e-78	265.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1INTS@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158343_k127_633810_286	1086011.HJ01_03285	9.404e-24	106.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_633810_346	1541065.JRFE01000014_gene1180	1.517e-07	58.0	2BVEX@1|root,32QUF@2|Bacteria,1GRAW@1117|Cyanobacteria	1117|Cyanobacteria	S	Family of unknown function (DUF5335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5335
SRR25158343_k127_633810_265	1267533.KB906733_gene3397	2.474e-31	136.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_633810_262	1120949.KB903318_gene1999	1.016e-31	134.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DINJ@85008|Micromonosporales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158343_k127_633810_335	1267534.KB906759_gene1638	2.129e-09	68.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_633810_17	1101191.KI912577_gene2037	3.873e-194	639.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JSCQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158343_k127_633810_273	1173020.Cha6605_0957	2.657e-28	119.0	arCOG08935@1|root,32Z08@2|Bacteria,1GAUH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_214	797209.ZOD2009_10355	2.563e-50	187.0	arCOG13341@1|root,arCOG13341@2157|Archaea,2XXWE@28890|Euryarchaeota,23WKG@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_278	240015.ACP_2535	2.561e-26	114.0	COG0071@1|root,COG0071@2|Bacteria,3Y8FE@57723|Acidobacteria,2JNDQ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934,HSP20
SRR25158343_k127_633810_293	743722.Sph21_2115	4.44e-21	98.0	COG3467@1|root,COG3467@2|Bacteria,4NQFR@976|Bacteroidetes,1ITPB@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158343_k127_633810_281	1112216.JH594425_gene339	1.946e-24	104.0	COG2261@1|root,COG2261@2|Bacteria,1NNKP@1224|Proteobacteria,2UGGY@28211|Alphaproteobacteria,2K82R@204457|Sphingomonadales	204457|Sphingomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158343_k127_633810_322	518766.Rmar_1007	5.51e-13	79.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1FJR9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_633810_114	211165.AJLN01000094_gene1126	6.141e-94	327.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG5278@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5278@2|Bacteria,1GK1J@1117|Cyanobacteria,1JKBT@1189|Stigonemataceae	1117|Cyanobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158343_k127_633810_69	204669.Acid345_0751	1.456e-128	426.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_633810_1	671143.DAMO_1138	0.0	1052.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdxB	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158343_k127_633810_343	1340493.JNIF01000004_gene374	5.619e-08	61.0	297M3@1|root,2ZUU3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_39	1128421.JAGA01000002_gene335	3.072e-154	499.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158343_k127_633810_55	643473.KB235930_gene2840	1.399e-135	460.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIYG@1161|Nostocales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,Response_reg
SRR25158343_k127_633810_189	720554.Clocl_1813	6.742e-58	208.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WIMJ@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158343_k127_633810_229	1267535.KB906767_gene3059	1.218e-44	165.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria,2JJ9V@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158343_k127_633810_139	926569.ANT_28060	1.215e-79	273.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158343_k127_633810_289	1385513.N780_10825	1.437e-22	105.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,2YA7R@289201|Pontibacillus	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158343_k127_633810_310	56780.SYN_00766	1.564e-17	84.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MQIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158343_k127_633810_304	1499967.BAYZ01000028_gene1320	4.806e-19	89.0	COG0228@1|root,COG0228@2|Bacteria,2NPWN@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158343_k127_633810_47	234267.Acid_2573	1.427e-147	482.0	COG0541@1|root,COG0541@2|Bacteria,3Y3AU@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158343_k127_633810_360	1224318.DT73_07900	0.0001219	51.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Periplasmic or secreted lipoprotein	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158343_k127_633810_246	234267.Acid_2356	2.373e-37	154.0	COG0859@1|root,COG0859@2|Bacteria,3Y616@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158343_k127_633810_150	1463821.JOGR01000001_gene1376	3.224e-76	263.0	COG2227@1|root,COG2227@2|Bacteria,2I8GJ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_633810_312	234267.Acid_2357	2.599e-17	83.0	COG2835@1|root,COG2835@2|Bacteria,3Y8VE@57723|Acidobacteria	57723|Acidobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158343_k127_633810_4	1183438.GKIL_3129	7.861e-302	937.0	COG0365@1|root,COG0365@2|Bacteria,1G0E7@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158343_k127_633810_368	395965.Msil_1613	0.0004327	49.0	294WE@1|root,2ZS9E@2|Bacteria,1R3S1@1224|Proteobacteria,2U2AB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_110	1198114.AciX9_1463	4.898e-99	370.0	COG0457@1|root,COG0457@2|Bacteria	1198114.AciX9_1463|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_33	682795.AciX8_0335	1.017e-163	543.0	COG2304@1|root,COG2304@2|Bacteria,3Y5S3@57723|Acidobacteria	57723|Acidobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SRR25158343_k127_633810_233	682795.AciX8_0336	2.808e-42	176.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K19693	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Reg_prop
SRR25158343_k127_633810_241	234267.Acid_2189	1.546e-39	170.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y2ZI@57723|Acidobacteria	57723|Acidobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158343_k127_633810_236	338963.Pcar_3086	1.963e-40	159.0	COG2197@1|root,COG2197@2|Bacteria,1PHR7@1224|Proteobacteria,42UJB@68525|delta/epsilon subdivisions,2WQPN@28221|Deltaproteobacteria,43SQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158343_k127_633810_344	926566.Terro_3361	1.002e-07	63.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,DUF2637,TonB_C,YXWGXW
SRR25158343_k127_633810_317	1453505.JASY01000002_gene2543	8.18e-16	85.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia,2NTW5@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
SRR25158343_k127_633810_341	1205680.CAKO01000029_gene5066	4.244e-08	61.0	2BRJ3@1|root,32KI7@2|Bacteria,1RI18@1224|Proteobacteria,2U8IN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_221	365044.Pnap_1409	3.024e-47	173.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,4AERU@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158343_k127_633810_269	1340493.JNIF01000003_gene2460	2.191e-29	132.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_633810_73	234267.Acid_3614	9.425e-126	414.0	COG1060@1|root,COG1060@2|Bacteria,3Y2IA@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158343_k127_633810_242	306281.AJLK01000148_gene1872	4.454e-39	151.0	COG1695@1|root,COG1695@2|Bacteria,1G79H@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158343_k127_633810_232	204669.Acid345_3342	2.112e-43	169.0	COG1427@1|root,COG1427@2|Bacteria,3Y3PU@57723|Acidobacteria,2JIWB@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158343_k127_633810_208	632335.Calkr_2020	1.031e-51	191.0	COG1878@1|root,COG1878@2|Bacteria,1UFUJ@1239|Firmicutes,24HGD@186801|Clostridia,42GJQ@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM cyclase family protein	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158343_k127_633810_285	937777.Deipe_2668	7.935e-24	104.0	COG3695@1|root,COG3695@2|Bacteria	2|Bacteria	L	enzyme binding	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,YjbR
SRR25158343_k127_633810_122	1210884.HG799468_gene13789	2.699e-90	322.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158343_k127_633810_68	1089553.Tph_c10350	3.03e-129	429.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,42EX2@68295|Thermoanaerobacterales	186801|Clostridia	C	FAD linked oxidase	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158343_k127_633810_296	1117314.PCIT_22454	2.584e-20	98.0	COG2062@1|root,COG2062@2|Bacteria,1QVVF@1224|Proteobacteria,1T2K8@1236|Gammaproteobacteria,2Q5H5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158343_k127_633810_129	861299.J421_0799	1.474e-86	296.0	COG0657@1|root,COG0657@2|Bacteria,1ZTVM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	alpha/beta hydrolase fold	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158343_k127_633810_134	797209.ZOD2009_13761	1.848e-83	292.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVFS@28890|Euryarchaeota,23UCU@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158343_k127_633810_43	929556.Solca_3153	1.437e-151	501.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158343_k127_633810_86	324602.Caur_0607	3.498e-117	399.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
SRR25158343_k127_633810_201	1070319.CAGGBEG34_190038	1.732e-53	209.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158343_k127_633810_34	696369.KI912183_gene1959	2.011e-162	526.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2602C@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158343_k127_633810_210	929703.KE386491_gene3265	5.492e-51	184.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,47Y1I@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158343_k127_633810_176	1033810.HLPCO_002620	7.606e-62	218.0	COG0703@1|root,COG0703@2|Bacteria	2|Bacteria	F	shikimate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
SRR25158343_k127_633810_188	360911.EAT1b_0098	4.248e-58	208.0	COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli	91061|Bacilli	F	topology modulation protein	flaR	-	-	-	-	-	-	-	-	-	-	-	AAA_18,ABC_tran
SRR25158343_k127_633810_15	889378.Spiaf_0670	2.086e-197	623.0	COG0148@1|root,COG0148@2|Bacteria,2J59Y@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158343_k127_633810_80	525897.Dbac_2296	1.822e-118	395.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2M7ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Transporter-associated region	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158343_k127_633810_243	237368.SCABRO_01532	3.275e-38	151.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria	2|Bacteria	C	iron-sulfur transferase activity	nifU	-	-	ko:K07126,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
SRR25158343_k127_633810_291	204669.Acid345_0181	2.405e-21	101.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158343_k127_633810_297	215803.DB30_0160	2.746e-20	96.0	COG1051@1|root,COG1051@2|Bacteria,1QX3X@1224|Proteobacteria,437EV@68525|delta/epsilon subdivisions,2X2M4@28221|Deltaproteobacteria,2YZWY@29|Myxococcales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_633810_99	1267535.KB906767_gene5069	8.497e-110	363.0	28HGI@1|root,2Z7SC@2|Bacteria,3Y3VE@57723|Acidobacteria,2JICD@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_258	105559.Nwat_0733	1.836e-32	133.0	COG1416@1|root,COG1416@2|Bacteria,1RFD1@1224|Proteobacteria,1S7R2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur reduction protein DsrE	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158343_k127_633810_11	247490.KSU1_B0460	4.447e-214	683.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158343_k127_633810_82	485913.Krac_1373	4.738e-118	397.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158343_k127_633810_36	318996.AXAZ01000054_gene6389	9.829e-160	517.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158343_k127_633810_363	1229203.KI301992_gene876	0.0002042	49.0	2BJUH@1|root,32E6P@2|Bacteria,2HX37@201174|Actinobacteria,3UXKN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158343_k127_633810_65	240015.ACP_2383	9.969e-131	426.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158343_k127_633810_155	240015.ACP_2560	3.273e-73	252.0	COG1136@1|root,COG1136@2|Bacteria,3Y3JD@57723|Acidobacteria,2JIHH@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_633810_316	234267.Acid_7919	5.419e-16	90.0	COG2834@1|root,COG2834@2|Bacteria,3Y4A1@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
SRR25158343_k127_633810_307	401053.AciPR4_4037	5.611e-18	88.0	2DR0H@1|root,339NS@2|Bacteria,3Y59F@57723|Acidobacteria,2JJP9@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Caa(3)-type oxidase, subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158343_k127_633810_174	278963.ATWD01000001_gene3302	9.506e-63	226.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria,2JI50@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158343_k127_633810_7	234267.Acid_0498	1.782e-258	806.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158343_k127_633810_109	204669.Acid345_2996	2.049e-101	342.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158343_k127_633810_128	886293.Sinac_3660	5.918e-87	297.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158343_k127_633810_359	1316927.ATKI01000061_gene4040	0.0001116	51.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_104	234267.Acid_0494	3.406e-106	359.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria	57723|Acidobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_200	204669.Acid345_3000	1.139e-53	199.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158343_k127_633810_183	1128421.JAGA01000003_gene2872	1.325e-59	211.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SRR25158343_k127_633810_16	1128421.JAGA01000003_gene2871	2.36e-196	622.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SRR25158343_k127_633810_2	1128421.JAGA01000003_gene2870	2e-323	1022.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SRR25158343_k127_633810_137	525904.Tter_1596	3.488e-82	279.0	COG3880@1|root,COG3880@2|Bacteria,2NPCX@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,GSu_C4xC__C2xCH,UVR
SRR25158343_k127_633810_268	1260356.D920_02676	5.67e-30	131.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,4AZ7R@81852|Enterococcaceae	91061|Bacilli	G	ROK family	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
SRR25158343_k127_633810_315	316067.Geob_3138	1.584e-16	89.0	COG0586@1|root,COG0586@2|Bacteria,1NBBA@1224|Proteobacteria,42MFR@68525|delta/epsilon subdivisions,2WR9B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158343_k127_633810_131	204669.Acid345_2431	4.678e-86	295.0	COG2605@1|root,COG2605@2|Bacteria,3Y56A@57723|Acidobacteria,2JP24@204432|Acidobacteriia	204432|Acidobacteriia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158343_k127_633810_311	379066.GAU_0274	2.565e-17	92.0	2DD36@1|root,2ZGAH@2|Bacteria,1ZU63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_119	240015.ACP_0725	3.246e-92	309.0	COG0047@1|root,COG0047@2|Bacteria,3Y2YN@57723|Acidobacteria,2JIBA@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158343_k127_633810_295	1238182.C882_1353	1.267e-20	93.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2JTEV@204441|Rhodospirillales	204441|Rhodospirillales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158343_k127_633810_326	234267.Acid_6361	5.342e-11	68.0	COG4818@1|root,COG4818@2|Bacteria,3Y5MZ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,zinc_ribbon_2
SRR25158343_k127_633810_27	335543.Sfum_0660	2.918e-166	533.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2MREF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158343_k127_633810_362	224308.BSU03540	0.0001615	51.0	2E30Y@1|root,32Y1E@2|Bacteria,1VF3X@1239|Firmicutes,4HNVI@91061|Bacilli,1ZKJM@1386|Bacillus	91061|Bacilli	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
SRR25158343_k127_633810_91	1094980.Mpsy_1929	2.741e-114	377.0	COG0136@1|root,arCOG00494@2157|Archaea,2XTKH@28890|Euryarchaeota,2N920@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM Semialdehyde dehydrogenase NAD - binding	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158343_k127_633810_340	743720.Psefu_0146	3.801e-08	58.0	2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR25158343_k127_633810_299	1123278.KB893441_gene1918	3.92e-20	102.0	2960U@1|root,2ZTBG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_354	1227261.HMPREF0043_01305	1.587e-05	55.0	2A46Z@1|root,30SS6@2|Bacteria,2H936@201174|Actinobacteria,4D7MF@85005|Actinomycetales	201174|Actinobacteria	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
SRR25158343_k127_633810_50	1183438.GKIL_2901	2.987e-143	481.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_2901|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_633810_347	998674.ATTE01000001_gene920	3.612e-07	60.0	COG0775@1|root,COG4783@1|root,COG0775@2|Bacteria,COG4783@2|Bacteria,1QXHY@1224|Proteobacteria	1224|Proteobacteria	F	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR25158343_k127_633810_179	234267.Acid_1127	2.994e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_633810_170	351627.Csac_1960	6.525e-66	239.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42F6W@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	aspC	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_633810_95	592026.GCWU0000282_000316	2.1e-110	366.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158343_k127_633810_305	374847.Kcr_0038	1.604e-18	92.0	COG0456@1|root,arCOG00833@2157|Archaea	2157|Archaea	C	PFAM GCN5-related N-acetyltransferase	-	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158343_k127_633810_225	386415.NT01CX_0248	6.868e-46	173.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,36I8K@31979|Clostridiaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158343_k127_633810_59	204669.Acid345_0689	4.332e-134	439.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158343_k127_633810_348	1121405.dsmv_0774	5.735e-07	60.0	COG0784@1|root,COG0784@2|Bacteria,1RHWK@1224|Proteobacteria,42SCZ@68525|delta/epsilon subdivisions,2WPGH@28221|Deltaproteobacteria,2MK6H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SRR25158343_k127_633810_96	1198114.AciX9_2892	3.373e-110	387.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158343_k127_633810_270	1382359.JIAL01000001_gene2418	4.296e-29	129.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_633810_339	1267533.KB906734_gene4216	3.408e-08	57.0	arCOG13401@1|root,33MMV@2|Bacteria,3Y5TE@57723|Acidobacteria,2JNR5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
SRR25158343_k127_633810_181	1340493.JNIF01000003_gene2102	5.363e-60	219.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
SRR25158343_k127_633810_226	1487953.JMKF01000053_gene1809	1.343e-45	173.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,1HA80@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158343_k127_633810_38	1379698.RBG1_1C00001G0745	2.643e-156	512.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158343_k127_633810_205	861299.J421_0340	1.39e-52	198.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158343_k127_633810_120	449447.MAE_45090	3.529e-92	314.0	COG0500@1|root,COG0500@2|Bacteria,1GQ10@1117|Cyanobacteria	1117|Cyanobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158343_k127_633810_204	1121887.AUDK01000026_gene1956	1.061e-52	194.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia,2NSSS@237|Flavobacterium	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158343_k127_633810_240	379066.GAU_1192	7.582e-40	158.0	COG1234@1|root,COG1234@2|Bacteria,1ZT5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158343_k127_633810_84	1382359.JIAL01000001_gene2411	7.898e-118	395.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_633810_22	234267.Acid_3565	3.309e-173	590.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	ASH,CarboxypepD_reg,DUF11,FlgD_ig,HYR,Laminin_G_3,Plug,TonB_dep_Rec
SRR25158343_k127_633810_190	861299.J421_4352	9.089e-58	211.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158343_k127_633810_74	234267.Acid_7871	5.046e-124	419.0	COG0616@1|root,COG0616@2|Bacteria,3Y3M1@57723|Acidobacteria	57723|Acidobacteria	OU	PFAM peptidase S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158343_k127_633810_41	621372.ACIH01000238_gene2054	2.07e-153	496.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,26RY1@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158343_k127_633810_169	1492737.FEM08_00190	1.381e-66	230.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1I1DP@117743|Flavobacteriia,2NW3U@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158343_k127_633810_272	929562.Emtol_2413	1.433e-28	120.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,47PZ9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158343_k127_633810_106	316067.Geob_1802	5.614e-103	348.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158343_k127_633810_259	5888.CAK71852	2.179e-32	140.0	KOG0032@1|root,KOG0032@2759|Eukaryota,3ZB73@5878|Ciliophora	5878|Ciliophora	T	EF-hand domain pair	-	-	2.7.11.1	ko:K13412	ko04626,ko05145,map04626,map05145	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	EF-hand_1,EF-hand_5,EF-hand_7,Pkinase
SRR25158343_k127_633810_143	237368.SCABRO_03899	7.366e-79	270.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158343_k127_633810_275	1499684.CCNP01000018_gene1061	3.677e-27	121.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,36H7U@31979|Clostridiaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158343_k127_633810_180	272123.Anacy_4111	1.409e-60	215.0	COG0220@1|root,COG0220@2|Bacteria,1G312@1117|Cyanobacteria,1HJXW@1161|Nostocales	1117|Cyanobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SRR25158343_k127_633810_213	1340493.JNIF01000004_gene944	1.71e-50	198.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158343_k127_633810_218	243231.GSU0388	3.006e-49	183.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158343_k127_633810_90	1379698.RBG1_1C00001G0364	1.802e-115	381.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158343_k127_633810_364	349124.Hhal_1506	0.0002521	51.0	COG4818@1|root,COG4818@2|Bacteria	2|Bacteria	S	TM2 domain	M1-746	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SRR25158343_k127_633810_42	1424334.W822_18305	1.324e-152	492.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VKAV@28216|Betaproteobacteria,3T22D@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
SRR25158343_k127_633810_250	1173022.Cri9333_1771	4.224e-35	149.0	COG2898@1|root,COG2898@2|Bacteria,1G1E7@1117|Cyanobacteria,1H7PX@1150|Oscillatoriales	1117|Cyanobacteria	S	'Conserved protein	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,tRNA-synt_2_TM
SRR25158343_k127_633810_18	1122216.AUHW01000012_gene1521	4.222e-190	610.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4H32N@909932|Negativicutes	909932|Negativicutes	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
SRR25158343_k127_633810_102	1173023.KE650771_gene5328	5.599e-109	357.0	COG1136@1|root,COG1136@2|Bacteria,1G4IP@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_633810_5	489825.LYNGBM3L_63180	1.553e-271	856.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,1H9BF@1150|Oscillatoriales	1117|Cyanobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158343_k127_633810_159	331678.Cphamn1_1477	1.445e-68	243.0	COG0845@1|root,COG0845@2|Bacteria,1FEGG@1090|Chlorobi	1090|Chlorobi	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
SRR25158343_k127_633810_239	1499967.BAYZ01000078_gene990	4.157e-40	159.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
SRR25158343_k127_633810_135	313596.RB2501_03270	2.448e-83	284.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158343_k127_633810_287	1166018.FAES_0248	1.393e-23	103.0	COG3502@1|root,COG3502@2|Bacteria,4NV0K@976|Bacteroidetes,47SFX@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
SRR25158343_k127_633810_187	1499684.CCNP01000015_gene357	9.911e-59	212.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,36DP0@31979|Clostridiaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158343_k127_633810_185	1123368.AUIS01000020_gene1105	2.651e-59	211.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,1T880@1236|Gammaproteobacteria,2NCF2@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158343_k127_633810_224	1291050.JAGE01000001_gene3018	4.738e-46	176.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
SRR25158343_k127_633810_237	204669.Acid345_4287	2.504e-40	155.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria,2JJ9D@204432|Acidobacteriia	204432|Acidobacteriia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158343_k127_633810_219	1173029.JH980292_gene2496	6.368e-49	193.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158343_k127_633810_29	118166.JH976537_gene17	8.783e-166	531.0	COG1232@1|root,COG1232@2|Bacteria,1GBRP@1117|Cyanobacteria,1HF96@1150|Oscillatoriales	1117|Cyanobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158343_k127_633810_89	272134.KB731324_gene4073	1.207e-115	380.0	COG0500@1|root,COG2226@2|Bacteria,1GQU7@1117|Cyanobacteria,1HHZR@1150|Oscillatoriales	1117|Cyanobacteria	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158343_k127_633810_75	1173029.JH980292_gene2498	1.133e-123	404.0	COG0726@1|root,COG0726@2|Bacteria,1G3JU@1117|Cyanobacteria,1HABD@1150|Oscillatoriales	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158343_k127_633810_46	272134.KB731324_gene4075	5.352e-148	483.0	COG1232@1|root,COG1232@2|Bacteria,1G465@1117|Cyanobacteria,1H9AU@1150|Oscillatoriales	1117|Cyanobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158343_k127_633810_125	272134.KB731324_gene4076	2.694e-88	295.0	COG0110@1|root,COG0110@2|Bacteria,1G65X@1117|Cyanobacteria,1H84W@1150|Oscillatoriales	1117|Cyanobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
SRR25158343_k127_633810_261	685727.REQ_44570	4.376e-32	127.0	COG2169@1|root,COG2169@2|Bacteria,2IQMA@201174|Actinobacteria,4G3ZH@85025|Nocardiaceae	201174|Actinobacteria	F	Metal binding domain of Ada	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
SRR25158343_k127_633810_72	272134.KB731324_gene4077	8.452e-126	411.0	COG0673@1|root,COG0673@2|Bacteria,1G0M6@1117|Cyanobacteria,1HA0M@1150|Oscillatoriales	1117|Cyanobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158343_k127_633810_35	272134.KB731324_gene4078	7.003e-161	517.0	COG0399@1|root,COG0399@2|Bacteria,1G3H0@1117|Cyanobacteria,1H8TM@1150|Oscillatoriales	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158343_k127_633810_19	1123508.JH636439_gene1510	5.09e-178	576.0	COG0463@1|root,COG0726@1|root,COG0463@2|Bacteria,COG0726@2|Bacteria,2IWT2@203682|Planctomycetes	203682|Planctomycetes	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Glycos_transf_2,Polysacc_deac_1
SRR25158343_k127_633810_100	240016.ABIZ01000001_gene1751	1.166e-109	368.0	COG0381@1|root,COG0381@2|Bacteria,46V5D@74201|Verrucomicrobia	74201|Verrucomicrobia	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158343_k127_633810_271	575540.Isop_1522	1.047e-28	117.0	COG1146@1|root,COG1146@2|Bacteria,2J013@203682|Planctomycetes	203682|Planctomycetes	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SRR25158343_k127_633810_66	1267535.KB906767_gene3449	1.423e-129	422.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158343_k127_633810_105	861299.J421_1210	6.505e-104	351.0	28JRE@1|root,2Z9H3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_112	272134.KB731324_gene3515	6.691e-98	348.0	2CAE5@1|root,313QD@2|Bacteria,1GCRF@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_8	1173028.ANKO01000124_gene2863	3.953e-252	816.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158343_k127_633810_350	1040987.AZUY01000007_gene748	2.669e-06	56.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,43JFG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_22745	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158343_k127_633810_276	573063.Metin_0198	5.975e-27	116.0	COG2314@1|root,COG3815@1|root,arCOG03293@2157|Archaea,arCOG03949@2157|Archaea,2XYU1@28890|Euryarchaeota,23RS2@183939|Methanococci	183939|Methanococci	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_357	1123065.ATWL01000004_gene2898	7.211e-05	49.0	2DRD4@1|root,33B9X@2|Bacteria,2GTDE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_108	156578.ATW7_01977	4.013e-102	349.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
SRR25158343_k127_633810_154	926561.KB900617_gene2293	1.301e-73	256.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3WAEH@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158343_k127_633810_57	661478.OP10G_2288	6.515e-135	449.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
SRR25158343_k127_633810_127	682795.AciX8_0370	4.564e-87	295.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR25158343_k127_633810_144	289376.THEYE_A0090	1.357e-78	270.0	COG1043@1|root,COG1043@2|Bacteria,3J0G6@40117|Nitrospirae	40117|Nitrospirae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158343_k127_633810_227	1382359.JIAL01000001_gene791	3.554e-45	168.0	COG0764@1|root,COG0764@2|Bacteria,3Y4CG@57723|Acidobacteria,2JJ97@204432|Acidobacteriia	204432|Acidobacteriia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158343_k127_633810_358	338966.Ppro_3018	9.517e-05	52.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,43SMD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158343_k127_633810_83	204669.Acid345_0248	6.724e-118	416.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria,2JHYD@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158343_k127_633810_3	1382359.JIAL01000001_gene2740	2.543e-307	960.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158343_k127_633810_196	397945.Aave_3700	1.212e-54	206.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,4AA4E@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158343_k127_633810_61	471854.Dfer_5079	1.753e-133	439.0	COG1231@1|root,COG1231@2|Bacteria,4NJU7@976|Bacteroidetes,47NP2@768503|Cytophagia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158343_k127_633810_54	443143.GM18_3009	6.595e-136	443.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158343_k127_633810_217	278963.ATWD01000001_gene1705	1.671e-49	205.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158343_k127_633810_175	204669.Acid345_2476	5.581e-62	244.0	COG0729@1|root,COG4775@1|root,COG0729@2|Bacteria,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SRR25158343_k127_633810_31	1267535.KB906767_gene4686	3.519e-164	539.0	COG1305@1|root,COG1305@2|Bacteria,3Y3A2@57723|Acidobacteria	57723|Acidobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SRR25158343_k127_633810_58	1267535.KB906767_gene4685	4.023e-134	451.0	COG1305@1|root,COG1305@2|Bacteria,3Y2TK@57723|Acidobacteria,2JHX7@204432|Acidobacteriia	204432|Acidobacteriia	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SRR25158343_k127_633810_20	555779.Dthio_PD2814	3e-176	557.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2M98D@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158343_k127_633810_161	468059.AUHA01000002_gene399	1.561e-68	238.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes	976|Bacteroidetes	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158343_k127_633810_118	502025.Hoch_6778	3.083e-92	312.0	COG0491@1|root,COG0491@2|Bacteria,1Q2NG@1224|Proteobacteria,4389J@68525|delta/epsilon subdivisions,2X3IZ@28221|Deltaproteobacteria,2YWA6@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158343_k127_633810_202	1333507.AUTQ01000260_gene3680	3.016e-53	195.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,2Q13K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158343_k127_633810_203	1129794.C427_3346	5.061e-53	190.0	COG0454@1|root,COG0456@2|Bacteria,1RJ1K@1224|Proteobacteria,1S6RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_633810_182	1267533.KB906734_gene4092	1.277e-59	212.0	COG1225@1|root,COG1225@2|Bacteria,3Y4W0@57723|Acidobacteria,2JJ7A@204432|Acidobacteriia	204432|Acidobacteriia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158343_k127_633810_156	926554.KI912637_gene3425	3.141e-72	255.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158343_k127_633810_361	421072.IO89_15200	0.0001546	46.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia,3HHED@358033|Chryseobacterium	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158343_k127_633810_48	1173026.Glo7428_3072	2.49e-147	496.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G0P4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SRR25158343_k127_633810_111	234267.Acid_2600	5.479e-98	329.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_78	926569.ANT_00770	3.012e-121	441.0	COG2373@1|root,COG2373@2|Bacteria,2G8BN@200795|Chloroflexi	200795|Chloroflexi	S	A-macroglobulin receptor	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
SRR25158343_k127_633810_319	1198114.AciX9_2169	1.291e-14	80.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_633810_138	1120973.AQXL01000128_gene2864	5.039e-82	284.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,2789H@186823|Alicyclobacillaceae	91061|Bacilli	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158343_k127_633810_274	234267.Acid_6217	1.594e-27	124.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_633810_158	1173020.Cha6605_4325	1.227e-70	246.0	COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158343_k127_633810_40	648996.Theam_0211	3.958e-154	499.0	COG1206@1|root,COG1206@2|Bacteria,2G3NY@200783|Aquificae	200783|Aquificae	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158343_k127_633810_329	748727.CLJU_c01460	7.97e-11	71.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,36FHM@31979|Clostridiaceae	186801|Clostridia	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158343_k127_633810_64	1183438.GKIL_0215	3.541e-131	457.0	COG0443@1|root,COG0443@2|Bacteria,1G1EM@1117|Cyanobacteria	1117|Cyanobacteria	O	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_149	1122216.AUHW01000005_gene530	1.539e-76	276.0	COG0206@1|root,COG0206@2|Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin,Tubulin_2
SRR25158343_k127_633810_366	533247.CRD_02230	0.0003092	49.0	2ET2G@1|root,33KKN@2|Bacteria,1GAYY@1117|Cyanobacteria,1HS7T@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_245	927677.ALVU02000001_gene2487	1.602e-37	158.0	2CC1C@1|root,2ZVZA@2|Bacteria,1G6DH@1117|Cyanobacteria,1H5Z5@1142|Synechocystis	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_136	118161.KB235922_gene1842	3.967e-83	290.0	28MUN@1|root,2ZB2G@2|Bacteria,1G3VC@1117|Cyanobacteria	1117|Cyanobacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
SRR25158343_k127_633810_249	1354303.M917_1571	3.685e-35	145.0	COG3183@1|root,COG3183@2|Bacteria,1MZRA@1224|Proteobacteria,1SA0W@1236|Gammaproteobacteria,3NMCQ@468|Moraxellaceae	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR25158343_k127_633810_26	1280679.ATVX01000013_gene2584	8.802e-167	535.0	2CCB0@1|root,2Z8JN@2|Bacteria,1VDSG@1239|Firmicutes,24Q8M@186801|Clostridia	186801|Clostridia	S	NurA domain	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR25158343_k127_633810_6	439235.Dalk_0399	5.74e-267	836.0	COG0433@1|root,COG0433@2|Bacteria,1R7TJ@1224|Proteobacteria,42XP2@68525|delta/epsilon subdivisions,2WSTV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
SRR25158343_k127_633810_199	632292.Calhy_0017	1.09e-53	195.0	COG0500@1|root,COG0500@2|Bacteria,1UI1D@1239|Firmicutes,25EAD@186801|Clostridia	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,NUDIX
SRR25158343_k127_633810_87	234267.Acid_6030	8.8e-117	385.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K06877,ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,Intron_maturas2,RVT_1
SRR25158343_k127_633810_178	641143.HMPREF9331_02382	2.017e-61	216.0	COG4502@1|root,COG4502@2|Bacteria,4NTF5@976|Bacteroidetes,1I4GR@117743|Flavobacteriia	976|Bacteroidetes	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
SRR25158343_k127_633810_184	767817.Desgi_0258	1.781e-59	223.0	2CAZK@1|root,3005R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_349	1471459.JFLJ01000130_gene1468	1.253e-06	59.0	2AH0G@1|root,3179B@2|Bacteria,1GIPU@1117|Cyanobacteria,1MNER@1212|Prochloraceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_153	373994.Riv7116_3958	1.925e-74	256.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HM2J@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158343_k127_633810_107	373994.Riv7116_5472	1.824e-102	348.0	COG0389@1|root,COG0389@2|Bacteria,1G07F@1117|Cyanobacteria	1117|Cyanobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
SRR25158343_k127_633810_292	1137281.D778_02695	3.57e-21	98.0	COG1974@1|root,COG1974@2|Bacteria,4NQXK@976|Bacteroidetes,1I2WU@117743|Flavobacteriia	976|Bacteroidetes	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158343_k127_633810_264	1173023.KE650771_gene4075	2.456e-31	139.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1JIDX@1189|Stigonemataceae	1117|Cyanobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158343_k127_633810_331	1048983.EL17_00800	8.929e-11	71.0	COG3103@1|root,COG3103@2|Bacteria,4P4QK@976|Bacteroidetes	976|Bacteroidetes	T	Protein of unknown function (DUF3761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3761,SH3_3
SRR25158343_k127_633810_298	556268.OFAG_00319	3.892e-20	100.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
SRR25158343_k127_633810_160	761193.Runsl_4889	1.56e-68	249.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,47JAH@768503|Cytophagia	976|Bacteroidetes	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
SRR25158343_k127_633810_81	1165096.ARWF01000001_gene2387	2.648e-118	412.0	COG5519@1|root,COG5519@2|Bacteria,1MW5H@1224|Proteobacteria,2VHZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Domain of unknown function (DUF927)	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	DUF927,PriCT_2,Toprim_3
SRR25158343_k127_633810_302	272560.BPSL3344	3.955e-19	100.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,2W247@28216|Betaproteobacteria,1KGXI@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158343_k127_633810_77	945713.IALB_1883	7.277e-122	413.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158343_k127_633810_267	1123242.JH636434_gene4709	1.294e-30	124.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158343_k127_633810_52	497964.CfE428DRAFT_4279	2.284e-137	452.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase middle domain protein	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_633810_140	517418.Ctha_1979	2.325e-79	274.0	COG0329@1|root,COG0329@2|Bacteria,1FDG2@1090|Chlorobi	1090|Chlorobi	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158343_k127_633810_244	1313421.JHBV01000031_gene1550	4.916e-38	151.0	COG0739@1|root,COG0739@2|Bacteria,4NMHB@976|Bacteroidetes	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158343_k127_633810_163	1173028.ANKO01000032_gene1752	8.085e-68	247.0	COG1835@1|root,COG1835@2|Bacteria,1GB27@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158343_k127_633810_117	1121904.ARBP01000005_gene4611	5.01e-93	309.0	COG0135@1|root,COG0135@2|Bacteria,4NK5D@976|Bacteroidetes,47NUD@768503|Cytophagia	976|Bacteroidetes	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158343_k127_633810_194	391598.FBBAL38_08510	5.647e-56	203.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158343_k127_633810_123	1382359.JIAL01000001_gene2279	4.396e-89	305.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria,2JIEY@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158343_k127_633810_157	1499967.BAYZ01000195_gene3083	3.257e-71	255.0	COG3372@1|root,COG3372@2|Bacteria	2|Bacteria	S	COGs COG3372 conserved	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
SRR25158343_k127_633810_49	1499967.BAYZ01000028_gene1368	1.523e-143	468.0	COG1061@1|root,COG1061@2|Bacteria,2NRQG@2323|unclassified Bacteria	2|Bacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158343_k127_633810_93	204669.Acid345_2491	1.673e-112	379.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
SRR25158343_k127_633810_334	164757.Mjls_4975	1.04e-09	65.0	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria,239A7@1762|Mycobacteriaceae	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
SRR25158343_k127_633810_165	1047013.AQSP01000111_gene1662	1.065e-67	239.0	COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158343_k127_633810_132	204669.Acid345_4498	5.069e-86	296.0	COG2021@1|root,COG2021@2|Bacteria,3Y4EW@57723|Acidobacteria,2JMVK@204432|Acidobacteriia	204432|Acidobacteriia	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158343_k127_633810_12	204669.Acid345_4499	2.091e-211	663.0	COG2873@1|root,COG2873@2|Bacteria,3Y2JU@57723|Acidobacteria,2JMB4@204432|Acidobacteriia	204432|Acidobacteriia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158343_k127_633810_168	1379698.RBG1_1C00001G1640	1.349e-66	235.0	COG1028@1|root,COG1028@2|Bacteria,2NP4D@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158343_k127_633810_328	485913.Krac_6686	7.109e-11	64.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
SRR25158343_k127_633810_248	485913.Krac_12343	2.085e-36	157.0	COG0515@1|root,COG0515@2|Bacteria	485913.Krac_12343|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_13	518766.Rmar_1427	2.027e-208	668.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1FIMS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158343_k127_633810_94	215803.DB30_4900	6.735e-111	375.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_633810_309	644801.Psest_2912	1.125e-17	89.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,1S5VD@1236|Gammaproteobacteria,1Z2N5@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158343_k127_633810_173	306281.AJLK01000036_gene5772	5.822e-63	223.0	COG0122@1|root,COG0122@2|Bacteria,1G394@1117|Cyanobacteria,1JKIH@1189|Stigonemataceae	1117|Cyanobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158343_k127_633810_235	204669.Acid345_0634	1.241e-40	154.0	COG1522@1|root,COG1522@2|Bacteria,3Y52K@57723|Acidobacteria,2JJEJ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158343_k127_633810_171	5786.XP_003288594.1	8.945e-65	232.0	COG3186@1|root,KOG3820@2759|Eukaryota,3XFIR@554915|Amoebozoa	554915|Amoebozoa	E	Biopterin-dependent aromatic amino acid hydroxylase	-	GO:0000003,GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009073,GO:0009074,GO:0009095,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019438,GO:0019439,GO:0019752,GO:0019954,GO:0022607,GO:0034617,GO:0042737,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0048037,GO:0050662,GO:0051259,GO:0051262,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1902221,GO:1902222	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
SRR25158343_k127_633810_313	318167.Sfri_0485	2.6e-17	86.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,2QA85@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_633810_186	221288.JH992901_gene5571	3.392e-59	213.0	COG0664@1|root,COG0664@2|Bacteria,1G1UQ@1117|Cyanobacteria,1JIKW@1189|Stigonemataceae	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_633810_124	1237149.C900_03630	1.04e-88	299.0	COG0500@1|root,COG2226@2|Bacteria,4PBWW@976|Bacteroidetes,47WFT@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_633810_32	204669.Acid345_2004	5.146e-164	524.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158343_k127_633810_211	1123228.AUIH01000039_gene2897	6.483e-51	189.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1XJ3I@135619|Oceanospirillales	135619|Oceanospirillales	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158343_k127_633810_14	93220.LV28_03160	4.04e-201	634.0	COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,2VJUH@28216|Betaproteobacteria,1K0PW@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158343_k127_633810_147	204669.Acid345_2006	1.613e-77	269.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria,2JMV1@204432|Acidobacteriia	204432|Acidobacteriia	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_633810_24	1128421.JAGA01000001_gene2399	2.135e-172	551.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
SRR25158343_k127_633810_25	1121918.ARWE01000001_gene1717	5.271e-170	545.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43RZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Glutamine amidotransferases class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158343_k127_633810_352	1196031.ALEG01000029_gene3659	4.126e-06	54.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1V2NW@1239|Firmicutes,4HGAA@91061|Bacilli,1ZC79@1386|Bacillus	91061|Bacilli	KP	helix_turn_helix, Arsenical Resistance Operon Repressor	M1-798	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Rhodanese
SRR25158343_k127_633810_367	93220.LV28_14400	0.0003166	44.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,1K3HB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
SRR25158343_k127_633810_263	1434929.X946_5630	1.887e-31	128.0	2E7CC@1|root,331VJ@2|Bacteria,1N8TM@1224|Proteobacteria,2VVSE@28216|Betaproteobacteria,1KB49@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4087
SRR25158343_k127_633810_70	880073.Calab_0614	2.191e-127	417.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158343_k127_72914_0	382245.ASA_3009	3.273e-179	569.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1Y5B5@135624|Aeromonadales	135624|Aeromonadales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158343_k127_748287_38	1121289.JHVL01000038_gene2998	1.26e-06	54.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	prdR	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
SRR25158343_k127_748287_4	1121430.JMLG01000003_gene556	2.39e-218	694.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158343_k127_748287_27	1270196.JCKI01000010_gene781	1.496e-32	136.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1ISGX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158343_k127_748287_34	459495.SPLC1_S011080	1.884e-12	74.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,1FZWT@1117|Cyanobacteria,1H90D@1150|Oscillatoriales	1117|Cyanobacteria	CO	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158343_k127_748287_20	1210884.HG799463_gene9989	1.713e-50	184.0	COG1595@1|root,COG1595@2|Bacteria,2IZXS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158343_k127_748287_21	530564.Psta_1179	4.141e-42	166.0	28IQM@1|root,2Z8QA@2|Bacteria,2IY3I@203682|Planctomycetes	203682|Planctomycetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158343_k127_748287_2	886293.Sinac_0625	5.416e-261	833.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	2|Bacteria	S	PFAM Peptidase M16 inactive domain	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_748287_30	234267.Acid_4199	6.103e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,3Y6TU@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_748287_12	234267.Acid_2364	1.101e-97	334.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158343_k127_748287_1	234267.Acid_2365	0.0	1069.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158343_k127_748287_13	234267.Acid_2365	6.624e-88	317.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,3Y6DS@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158343_k127_748287_15	926549.KI421517_gene3389	7.459e-82	278.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,47R25@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158343_k127_748287_37	929562.Emtol_0553	9.819e-07	52.0	2EHP7@1|root,33BF0@2|Bacteria,4NYRZ@976|Bacteroidetes,47SMN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_748287_31	1340493.JNIF01000003_gene4370	5.924e-21	105.0	29UCR@1|root,30FP6@2|Bacteria,3Y4J8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_748287_28	272134.KB731324_gene3671	1.048e-30	124.0	COG2314@1|root,COG2314@2|Bacteria,1G9J3@1117|Cyanobacteria,1HDPD@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
SRR25158343_k127_748287_3	1267534.KB906758_gene2271	1.219e-237	771.0	COG1629@1|root,COG4771@2|Bacteria,3Y42T@57723|Acidobacteria,2JIWF@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_748287_0	945713.IALB_2232	0.0	1349.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_748287_19	748449.Halha_2399	5.491e-56	210.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158343_k127_748287_23	497965.Cyan7822_3560	3.546e-39	170.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,3KGI4@43988|Cyanothece	1117|Cyanobacteria	N	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
SRR25158343_k127_748287_29	457396.CSBG_00974	8.159e-29	126.0	COG0115@1|root,COG0115@2|Bacteria,1V3JS@1239|Firmicutes,24JA5@186801|Clostridia,36ISU@31979|Clostridiaceae	186801|Clostridia	EH	Aminotransferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158343_k127_748287_8	204669.Acid345_3357	9.942e-174	581.0	COG4191@1|root,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
SRR25158343_k127_748287_41	717606.PaecuDRAFT_2665	0.0006967	52.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1UJQY@1239|Firmicutes,4ITDJ@91061|Bacilli,270X3@186822|Paenibacillaceae	91061|Bacilli	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_748287_17	886293.Sinac_0607	1.183e-62	221.0	COG2323@1|root,COG2323@2|Bacteria,2J1PB@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158343_k127_748287_10	589865.DaAHT2_0507	6.014e-143	468.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MHXE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158343_k127_748287_25	1267535.KB906767_gene493	6.345e-34	136.0	COG0454@1|root,COG0454@2|Bacteria,3Y9FN@57723|Acidobacteria	57723|Acidobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158343_k127_748287_39	1077144.AGFF01000010_gene2660	1.945e-06	55.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	petC	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158343_k127_748287_16	309801.trd_A0816	1.714e-79	285.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158343_k127_748287_14	215803.DB30_7982	7.588e-88	297.0	COG0500@1|root,COG0500@2|Bacteria,1QX9N@1224|Proteobacteria,438JR@68525|delta/epsilon subdivisions,2X3UE@28221|Deltaproteobacteria,2YX4R@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158343_k127_748287_18	1382359.JIAL01000001_gene1364	9.767e-60	216.0	COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria,2JJCF@204432|Acidobacteriia	204432|Acidobacteriia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158343_k127_748287_36	945713.IALB_1682	7.498e-08	60.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR25158343_k127_748287_6	700598.Niako_0720	4.125e-205	649.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1IP31@117747|Sphingobacteriia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158343_k127_748287_11	204669.Acid345_0710	2.477e-130	430.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria,2JMAK@204432|Acidobacteriia	204432|Acidobacteriia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
SRR25158343_k127_748287_5	240015.ACP_0705	2.812e-209	657.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158343_k127_748287_26	234267.Acid_7287	2.429e-33	136.0	COG0461@1|root,COG0461@2|Bacteria,3Y6JQ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158343_k127_748287_35	1183438.GKIL_3013	2.3e-12	71.0	28VTD@1|root,2ZHV3@2|Bacteria,1GFYH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_748287_7	760568.Desku_1668	2.33e-179	576.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158343_k127_748287_40	1121430.JMLG01000003_gene634	0.0005583	51.0	COG3330@1|root,COG3330@2|Bacteria,1TY60@1239|Firmicutes,2578K@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912
SRR25158343_k127_748287_33	1121403.AUCV01000010_gene1338	1.1e-12	78.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158343_k127_748287_22	204669.Acid345_4722	5.636e-40	155.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJJZ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158343_k127_748287_9	497964.CfE428DRAFT_1748	4.991e-152	489.0	COG3392@1|root,COG3392@2|Bacteria,46WWM@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
SRR25158343_k127_748287_24	401526.TcarDRAFT_1317	1.968e-34	144.0	COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,4H25K@909932|Negativicutes	909932|Negativicutes	M	lipopolysaccharide heptosyltransferase	rfaF	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158343_k127_778851_7	204669.Acid345_4326	9.199e-67	237.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria,2JI3X@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158343_k127_778851_1	485918.Cpin_3266	6.488e-189	598.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158343_k127_778851_6	530564.Psta_0005	2.522e-67	237.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158343_k127_778851_3	1229204.AMYY01000001_gene2699	1.183e-109	370.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2U25U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
SRR25158343_k127_778851_2	762903.Pedsa_1232	4.854e-129	428.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
SRR25158343_k127_778851_5	1499967.BAYZ01000065_gene6109	6.982e-78	269.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
SRR25158343_k127_778851_10	1170562.Cal6303_3204	1.094e-32	135.0	2A97U@1|root,30YCI@2|Bacteria,1G5XN@1117|Cyanobacteria,1HNP9@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SRR25158343_k127_778851_9	857087.Metme_3122	2.161e-40	161.0	2DWHQ@1|root,32V1N@2|Bacteria,1NJ85@1224|Proteobacteria,1SQVJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_778851_11	1198114.AciX9_2169	1.861e-16	87.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_778851_4	204669.Acid345_4392	8.648e-104	367.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158343_k127_778851_8	1382356.JQMP01000001_gene1111	6.89e-41	174.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G64X@200795|Chloroflexi,27Z3R@189775|Thermomicrobia	189775|Thermomicrobia	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,GGDEF,NB-ARC,TPR_12
SRR25158343_k127_778851_0	1122176.KB903565_gene3328	1.536e-320	990.0	COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes	976|Bacteroidetes	C	Molybdopterin oxidoreductase	-	-	1.7.2.3,1.8.5.5	ko:K07812,ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.4,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158343_k127_822690_87	1297742.A176_06198	3.84e-19	92.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2YW5U@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158343_k127_822690_3	1382359.JIAL01000001_gene2069	1.533e-220	693.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158343_k127_822690_28	1089550.ATTH01000001_gene1831	2.091e-106	376.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
SRR25158343_k127_822690_60	234267.Acid_1209	6.669e-48	177.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_822690_106	1267534.KB906758_gene2456	1.289e-07	62.0	COG2885@1|root,COG2885@2|Bacteria,3Y310@57723|Acidobacteria,2JI18@204432|Acidobacteriia	57723|Acidobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_99	335659.S23_22370	7.091e-11	73.0	COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,3JW8J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
SRR25158343_k127_822690_7	926560.KE387023_gene3588	1.897e-180	574.0	COG1171@1|root,COG1171@2|Bacteria,1WJZG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158343_k127_822690_35	373903.Hore_14640	2.519e-84	293.0	COG0330@1|root,COG0330@2|Bacteria,1W711@1239|Firmicutes,25IRK@186801|Clostridia,3WC5Y@53433|Halanaerobiales	186801|Clostridia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158343_k127_822690_41	886293.Sinac_4789	6.196e-63	221.0	COG0386@1|root,COG0386@2|Bacteria,2IZ7Z@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158343_k127_822690_81	335543.Sfum_2529	6.936e-29	123.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MRXS@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158343_k127_822690_20	1122176.KB903532_gene2606	3.243e-127	416.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158343_k127_822690_69	204669.Acid345_4036	3.663e-39	156.0	COG0561@1|root,COG0561@2|Bacteria,3Y4J5@57723|Acidobacteria,2JJB7@204432|Acidobacteriia	204432|Acidobacteriia	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158343_k127_822690_59	321332.CYB_1473	3.419e-48	177.0	COG0652@1|root,COG0652@2|Bacteria,1G5BD@1117|Cyanobacteria,1H0AB@1129|Synechococcus	1117|Cyanobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rot	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158343_k127_822690_48	203119.Cthe_1343	1.727e-55	198.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158343_k127_822690_77	1569209.BBPH01000174_gene3844	4.992e-31	130.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,2PUPV@265|Paracoccus	28211|Alphaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768,ko:K09565	ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158343_k127_822690_82	204669.Acid345_3561	3.484e-25	117.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158343_k127_822690_67	1408436.JHXY01000005_gene35	7.991e-40	160.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25W0K@186806|Eubacteriaceae	186801|Clostridia	J	RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158343_k127_822690_53	399795.CtesDRAFT_PD2817	1.234e-50	184.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,4ADJH@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158343_k127_822690_63	1304284.L21TH_1877	5.784e-44	168.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36EIP@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
SRR25158343_k127_822690_23	204669.Acid345_0189	3.065e-119	394.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria,2JKNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158343_k127_822690_83	649747.HMPREF0083_01742	1.809e-23	109.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26QK6@186822|Paenibacillaceae	91061|Bacilli	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158343_k127_822690_8	742765.HMPREF9457_02698	5.185e-161	520.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,27UZ7@189330|Dorea	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158343_k127_822690_101	981369.JQMJ01000004_gene132	2.16e-09	66.0	2B5PB@1|root,31YIT@2|Bacteria,2HR65@201174|Actinobacteria,2NN1P@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_40	1487953.JMKF01000085_gene4325	2.239e-76	258.0	COG2343@1|root,COG2343@2|Bacteria,1G50P@1117|Cyanobacteria,1HAMP@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG2343 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158343_k127_822690_17	522306.CAP2UW1_2496	2.059e-134	443.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158343_k127_822690_64	204669.Acid345_1880	7.04e-44	164.0	28NYH@1|root,2ZBVN@2|Bacteria,3Y4V7@57723|Acidobacteria,2JJEB@204432|Acidobacteriia	204432|Acidobacteriia	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
SRR25158343_k127_822690_46	234267.Acid_1127	1.961e-57	209.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_822690_29	1340493.JNIF01000004_gene288	7.75e-103	357.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20951	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	PQQ_2
SRR25158343_k127_822690_95	65093.PCC7418_1251	4.715e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria	1117|Cyanobacteria	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
SRR25158343_k127_822690_110	335543.Sfum_3514	1.771e-05	48.0	COG3034@1|root,COG3034@2|Bacteria,1QTMV@1224|Proteobacteria,42W1K@68525|delta/epsilon subdivisions,2X5QE@28221|Deltaproteobacteria,2MS74@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158343_k127_822690_12	1382359.JIAL01000001_gene641	8.855e-151	486.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria,2JI0S@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158343_k127_822690_16	240015.ACP_3470	2.272e-135	439.0	COG0473@1|root,COG0473@2|Bacteria,3Y38Z@57723|Acidobacteria,2JHJJ@204432|Acidobacteriia	204432|Acidobacteriia	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158343_k127_822690_4	1329516.JPST01000001_gene982	8.063e-217	681.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,27AYD@186824|Thermoactinomycetaceae	91061|Bacilli	E	Aconitase family (aconitate hydratase)	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
SRR25158343_k127_822690_37	1118054.CAGW01000071_gene1761	2.173e-82	278.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,26RMU@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158343_k127_822690_92	59374.Fisuc_2558	2.244e-15	79.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	-	-	5.4.99.5	ko:K04092,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,MFS_1
SRR25158343_k127_822690_25	204669.Acid345_3110	1.344e-114	378.0	COG2876@1|root,COG2876@2|Bacteria,3Y64W@57723|Acidobacteria,2JMIX@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158343_k127_822690_47	1192034.CAP_1695	1.158e-56	212.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158343_k127_822690_55	1382359.JIAL01000001_gene2808	3.393e-50	188.0	COG0428@1|root,COG0428@2|Bacteria,3Y4A7@57723|Acidobacteria,2JJ1K@204432|Acidobacteriia	204432|Acidobacteriia	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
SRR25158343_k127_822690_84	591001.Acfer_0224	1.856e-23	111.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4H1Z7@909932|Negativicutes	909932|Negativicutes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158343_k127_822690_74	1267535.KB906767_gene2794	1.196e-35	145.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria,2JNB7@204432|Acidobacteriia	204432|Acidobacteriia	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_62	1267535.KB906767_gene2795	7.853e-45	170.0	COG1704@1|root,COG1704@2|Bacteria,3Y4QG@57723|Acidobacteria,2JJCD@204432|Acidobacteriia	204432|Acidobacteriia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158343_k127_822690_93	1191523.MROS_1787	1.226e-13	74.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SRR25158343_k127_822690_86	234267.Acid_0323	7.179e-20	91.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SRR25158343_k127_822690_75	234267.Acid_0322	1.653e-31	124.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
SRR25158343_k127_822690_72	215803.DB30_1141	1.988e-36	139.0	COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,42UCN@68525|delta/epsilon subdivisions,2WQ3V@28221|Deltaproteobacteria,2Z195@29|Myxococcales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
SRR25158343_k127_822690_44	234267.Acid_0320	5.861e-58	212.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria	57723|Acidobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158343_k127_822690_45	246194.CHY_0339	1.314e-57	208.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,42FJD@68295|Thermoanaerobacterales	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158343_k127_822690_52	682795.AciX8_4904	2.952e-51	189.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158343_k127_822690_78	269798.CHU_0267	1.425e-30	130.0	2CIQE@1|root,2ZR1N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_15	523791.Kkor_1853	9.184e-137	443.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1XIBE@135619|Oceanospirillales	135619|Oceanospirillales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158343_k127_822690_2	713586.KB900536_gene476	5.37e-273	863.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1WXK8@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158343_k127_822690_49	1123508.JH636439_gene1028	9.782e-55	203.0	COG0122@1|root,COG0122@2|Bacteria,2J0B5@203682|Planctomycetes	203682|Planctomycetes	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158343_k127_822690_79	5911.EAR90273	8.382e-30	135.0	COG0457@1|root,COG3914@1|root,KOG0591@1|root,KOG0591@2759|Eukaryota,KOG1124@2759|Eukaryota,KOG4626@2759|Eukaryota,3ZD0M@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_8
SRR25158343_k127_822690_34	357808.RoseRS_1529	7.883e-89	317.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_822690_109	1515613.HQ37_03595	4.79e-06	55.0	2EVRD@1|root,33P5B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_76	234267.Acid_6219	2.537e-31	135.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158343_k127_822690_38	715226.ABI_09510	5.042e-79	285.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158343_k127_822690_108	408672.NBCG_04886	2.134e-06	56.0	2EGCD@1|root,33A46@2|Bacteria,2GWRN@201174|Actinobacteria,4DSNQ@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,DUF4352
SRR25158343_k127_822690_54	234267.Acid_7677	1.338e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_822690_33	1183438.GKIL_2901	6.454e-101	355.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_2901|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_822690_9	1183438.GKIL_2901	1.231e-158	534.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_2901|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_822690_107	58123.JOFJ01000007_gene691	7.176e-07	53.0	2BKUK@1|root,32FAZ@2|Bacteria,2GZ3J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_88	203122.Sde_0642	1.177e-17	92.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR25158343_k127_822690_104	1300143.CCAV010000007_gene3258	8.634e-09	58.0	COG4461@1|root,COG4461@2|Bacteria,4NK5M@976|Bacteroidetes,1I16D@117743|Flavobacteriia,3ZRW5@59732|Chryseobacterium	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_36	62928.azo3774	1.519e-82	295.0	COG0515@1|root,COG0515@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pkn9	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_822690_50	1382306.JNIM01000001_gene897	9.606e-53	196.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158343_k127_822690_94	946483.Cenrod_0258	1.613e-13	77.0	COG0265@1|root,COG0265@2|Bacteria,1QVRK@1224|Proteobacteria	1224|Proteobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_43	379066.GAU_3832	4.478e-62	231.0	COG0515@1|root,COG0515@2|Bacteria	379066.GAU_3832|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_98	743836.AYNA01000147_gene549	2.014e-11	76.0	COG0265@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1716@2|Bacteria,1QJ3A@1224|Proteobacteria,2U3UY@28211|Alphaproteobacteria,36ZV6@31993|Methylocystaceae	28211|Alphaproteobacteria	OT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
SRR25158343_k127_822690_26	379066.GAU_3831	3.056e-111	382.0	COG0265@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K03220	-	M00332	-	-	ko00000,ko00002,ko02044	3.A.6.1	-	-	FHA,Trypsin,Trypsin_2
SRR25158343_k127_822690_70	420324.KI911956_gene3388	9.513e-39	149.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2U05I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158343_k127_822690_56	1313421.JHBV01000016_gene5604	8.662e-50	192.0	2DHAX@1|root,32U8Z@2|Bacteria	2|Bacteria	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158343_k127_822690_85	861299.J421_2716	2.532e-23	103.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_0	760192.Halhy_6518	0.0	1047.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IR4V@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
SRR25158343_k127_822690_91	1121920.AUAU01000015_gene1154	1.16e-16	87.0	2EPT7@1|root,33HDR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158343_k127_822690_42	118168.MC7420_553	9.205e-63	223.0	COG1592@1|root,COG1592@2|Bacteria,1G5YD@1117|Cyanobacteria,1HBFD@1150|Oscillatoriales	1117|Cyanobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158343_k127_822690_24	1121434.AULY01000012_gene2797	9.13e-117	390.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_822690_71	1121918.ARWE01000001_gene1838	1.661e-37	156.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,43BPZ@68525|delta/epsilon subdivisions,2X717@28221|Deltaproteobacteria,43SDR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	pilS	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158343_k127_822690_6	485918.Cpin_3752	1.859e-180	572.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1IV68@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
SRR25158343_k127_822690_32	1519464.HY22_10730	4.412e-101	344.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_822690_73	555088.DealDRAFT_1660	1.194e-35	139.0	COG2030@1|root,COG2030@2|Bacteria,1V6MY@1239|Firmicutes,24NB6@186801|Clostridia,42K0A@68298|Syntrophomonadaceae	186801|Clostridia	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158343_k127_822690_1	1094466.KQS_04245	7.26e-322	1014.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
SRR25158343_k127_822690_89	1524467.IV04_15070	2.599e-17	83.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria,1T1TK@1236|Gammaproteobacteria,400E6@613|Serratia	1236|Gammaproteobacteria	S	Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid	mhpC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0018771,GO:0019439,GO:0019622,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046164,GO:0046395,GO:0046435,GO:0052823,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616	3.7.1.14,3.7.1.8	ko:K05714,ko:K10222	ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220	M00543,M00545	R02603,R02606,R05359,R05360,R05361,R06789	RC00475,RC00476,RC00752,RC00753,RC00757,RC01337	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.ECDH10B_1361	Abhydrolase_1
SRR25158343_k127_822690_80	266265.Bxe_B0037	4.781e-29	125.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,2VIUP@28216|Betaproteobacteria,1K4F8@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid	mhpC	-	3.7.1.14	ko:K05714	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R02603,R06789	RC00752,RC00753,RC01337	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158343_k127_822690_30	639282.DEFDS_1468	2.256e-101	351.0	COG1022@1|root,COG1022@2|Bacteria,2GEWU@200930|Deferribacteres	200930|Deferribacteres	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158343_k127_822690_51	179408.Osc7112_2658	4.135e-52	191.0	COG5190@1|root,COG5190@2|Bacteria,1G5PJ@1117|Cyanobacteria,1HEF4@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM NLI interacting factor	-	-	-	-	-	-	-	-	-	-	-	-	NIF
SRR25158343_k127_822690_27	1144275.COCOR_07826	4.541e-111	369.0	COG0332@1|root,COG0332@2|Bacteria,1NSH9@1224|Proteobacteria,42Z79@68525|delta/epsilon subdivisions,2WUD8@28221|Deltaproteobacteria,2YUSN@29|Myxococcales	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158343_k127_822690_57	697303.Thewi_0630	1.393e-49	187.0	COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,247QR@186801|Clostridia,42H1C@68295|Thermoanaerobacterales	186801|Clostridia	I	Ndr family	-	-	1.11.1.10,3.1.1.24	ko:K00433,ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158343_k127_822690_11	1267533.KB906741_gene585	1.371e-154	529.0	COG1629@1|root,COG4771@2|Bacteria,3Y6Z9@57723|Acidobacteria,2JKTJ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_822690_103	398578.Daci_4533	4.099e-09	67.0	COG1309@1|root,COG1309@2|Bacteria,1PFFA@1224|Proteobacteria,2VUU9@28216|Betaproteobacteria,4AGMH@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158343_k127_822690_58	1049564.TevJSym_aa02470	5.871e-49	184.0	COG2215@1|root,COG2215@2|Bacteria,1R3QK@1224|Proteobacteria,1SARN@1236|Gammaproteobacteria,1JB4F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2,NicO
SRR25158343_k127_822690_19	1120934.KB894435_gene4438	1.334e-127	436.0	COG0019@1|root,COG3919@1|root,COG0019@2|Bacteria,COG3919@2|Bacteria,2H2S0@201174|Actinobacteria	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Orn_Arg_deC_N
SRR25158343_k127_822690_14	861299.J421_0736	6.171e-145	473.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158343_k127_822690_5	861299.J421_0737	1.149e-181	579.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158343_k127_822690_21	861299.J421_0738	6.429e-126	422.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158343_k127_822690_61	1385513.N780_05795	7.102e-46	169.0	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,2YANF@289201|Pontibacillus	91061|Bacilli	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158343_k127_822690_66	714943.Mucpa_2596	1.352e-42	158.0	COG2343@1|root,COG2343@2|Bacteria,4NSIC@976|Bacteroidetes,1ITCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158343_k127_822690_100	1173024.KI912148_gene3976	2.291e-10	71.0	2AH40@1|root,317DH@2|Bacteria,1GK7I@1117|Cyanobacteria,1JKJC@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_102	317936.Nos7107_1630	3.856e-09	66.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Cu_amine_oxidN1
SRR25158343_k127_822690_13	204669.Acid345_4299	1.935e-147	497.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria,2JHU4@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158343_k127_822690_31	1047013.AQSP01000113_gene754	4.32e-101	352.0	COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria	2|Bacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158343_k127_822690_10	1232410.KI421412_gene97	4.12e-155	508.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43SAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-70 factor, region 1.1	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158343_k127_822690_68	1408813.AYMG01000012_gene889	2.167e-39	150.0	2C5VR@1|root,32CJG@2|Bacteria,4NQV8@976|Bacteroidetes,1ITMX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_18	1304885.AUEY01000047_gene79	2.599e-134	449.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MI8S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158343_k127_822690_39	32057.KB217478_gene702	2.181e-77	274.0	COG0337@1|root,COG0337@2|Bacteria,1G03C@1117|Cyanobacteria,1HIJQ@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158343_k127_822690_90	43759.JNWK01000035_gene3291	9.095e-17	84.0	COG1670@1|root,COG1670@2|Bacteria,2IS7Y@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158343_k127_822690_22	401053.AciPR4_1260	3.447e-122	406.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158343_k127_822690_96	671143.DAMO_0870	9.066e-12	77.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	ko:K03194	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	CHAP,SLT
SRR25158343_k127_822690_105	452652.KSE_02830	1.608e-08	63.0	COG2954@1|root,COG2954@2|Bacteria,2IHDK@201174|Actinobacteria,2M36J@2063|Kitasatospora	201174|Actinobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_822690_65	986075.CathTA2_1922	1.8e-43	163.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli	91061|Bacilli	I	Dehydrogenase	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_862873_3	1198114.AciX9_2169	2.299e-19	94.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158343_k127_862873_4	1244869.H261_09387	5.722e-19	94.0	2CTAY@1|root,32ST0@2|Bacteria,1N57M@1224|Proteobacteria,2UDXZ@28211|Alphaproteobacteria,2JTMY@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_862873_2	926566.Terro_3400	2.057e-23	112.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_862873_1	236814.IX39_00835	5.12e-58	215.0	2CIIB@1|root,30490@2|Bacteria,4NPGD@976|Bacteroidetes,1I7VY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_862873_5	391009.Tmel_0308	7.732e-07	52.0	COG0338@1|root,COG0338@2|Bacteria,2GDKV@200918|Thermotogae	200918|Thermotogae	H	Site-specific DNA-methyltransferase (adenine-specific)	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158343_k127_868515_80	113355.CM001775_gene3329	1.399e-21	108.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	113355.CM001775_gene3329|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_67	330214.NIDE4035	6.087e-41	174.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158343_k127_868515_54	383372.Rcas_0336	5.102e-55	218.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158343_k127_868515_59	391625.PPSIR1_33781	2.109e-47	196.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SRR25158343_k127_868515_70	204669.Acid345_2954	2.758e-37	146.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria,2JJWZ@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158343_k127_868515_61	928724.SacglDRAFT_02272	2.383e-45	173.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4E2XM@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158343_k127_868515_63	1232410.KI421413_gene484	2.045e-44	166.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,437CT@68525|delta/epsilon subdivisions,2XA0U@28221|Deltaproteobacteria,43VKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158343_k127_868515_107	926566.Terro_2955	0.0005507	48.0	COG1629@1|root,COG4771@2|Bacteria,3Y2WI@57723|Acidobacteria,2JKNG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_868515_49	1086011.HJ01_03159	1.071e-60	214.0	COG0782@1|root,COG0782@2|Bacteria,4NM9C@976|Bacteroidetes,1I2YK@117743|Flavobacteriia,2NWBA@237|Flavobacterium	976|Bacteroidetes	K	Transcription elongation factor, GreA/GreB, C-term	-	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB
SRR25158343_k127_868515_16	1297570.MESS4_750051	8.897e-134	449.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,43KFD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158343_k127_868515_73	491915.Aflv_0680	9.437e-31	125.0	COG1876@1|root,COG1876@2|Bacteria,1V69M@1239|Firmicutes,4HI21@91061|Bacilli	91061|Bacilli	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	ycdD3	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,Peptidase_M15_4
SRR25158343_k127_868515_23	589865.DaAHT2_2162	1.551e-117	388.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,42MR3@68525|delta/epsilon subdivisions,2X2HD@28221|Deltaproteobacteria,2MNV8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SRR25158343_k127_868515_42	1487923.DP73_18500	7.302e-65	230.0	arCOG06916@1|root,30456@2|Bacteria,1VX97@1239|Firmicutes,2524T@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
SRR25158343_k127_868515_99	318464.IO99_13290	1.579e-05	49.0	2DKKM@1|root,309U3@2|Bacteria,1USJV@1239|Firmicutes,24ZBP@186801|Clostridia,36R54@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_101	172088.AUGA01000020_gene3550	5.942e-05	55.0	COG1705@1|root,COG1705@2|Bacteria,1Q6GA@1224|Proteobacteria,2VCM5@28211|Alphaproteobacteria,3K56M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MNU	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_91	1117647.M5M_09220	1.482e-09	61.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1J4SH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158343_k127_868515_9	1267534.KB906756_gene140	4.092e-181	599.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
SRR25158343_k127_868515_32	204669.Acid345_1052	2.984e-88	312.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_868515_8	204669.Acid345_1052	2.7e-183	602.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158343_k127_868515_18	234267.Acid_3528	8.36e-132	425.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria	57723|Acidobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158343_k127_868515_79	235909.GK0183	3.79e-24	108.0	COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,1WGBX@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF1569)	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_868515_19	391625.PPSIR1_29036	1.479e-124	415.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158343_k127_868515_72	234267.Acid_2675	3.986e-31	128.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158343_k127_868515_22	309801.trd_A0425	1.068e-118	400.0	COG2268@1|root,COG2268@2|Bacteria,2GBEI@200795|Chloroflexi,27Z5S@189775|Thermomicrobia	189775|Thermomicrobia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SRR25158343_k127_868515_102	1195236.CTER_0209	7.684e-05	52.0	COG1585@1|root,COG1585@2|Bacteria,1VD3E@1239|Firmicutes,24H38@186801|Clostridia,3WP65@541000|Ruminococcaceae	186801|Clostridia	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449,NfeD
SRR25158343_k127_868515_89	1267533.KB906733_gene2871	1.511e-14	83.0	28QZS@1|root,346UA@2|Bacteria,3Y8H4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_55	909663.KI867150_gene798	2.32e-51	186.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria,2MQJ3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
SRR25158343_k127_868515_51	1047013.AQSP01000111_gene1672	5.406e-60	220.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158343_k127_868515_78	1322246.BN4_11661	1.37e-26	112.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,43BPD@68525|delta/epsilon subdivisions,2X70Q@28221|Deltaproteobacteria,2MF45@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158343_k127_868515_44	1158338.JNLJ01000001_gene295	8.671e-63	222.0	COG0283@1|root,COG0283@2|Bacteria,2G3Z6@200783|Aquificae	200783|Aquificae	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158343_k127_868515_76	887062.HGR_08944	3.112e-27	113.0	arCOG13010@1|root,33AIE@2|Bacteria,1NJAU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_74	1107311.Q767_01975	3.221e-29	122.0	COG2315@1|root,COG2315@2|Bacteria,4NTRF@976|Bacteroidetes,1ID1Z@117743|Flavobacteriia,2NWYS@237|Flavobacterium	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158343_k127_868515_20	204669.Acid345_2367	2.284e-122	401.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria,2JIUS@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158343_k127_868515_82	1123248.KB893385_gene4832	1.145e-19	95.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1IPR4@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158343_k127_868515_21	1174528.JH992892_gene6553	9.859e-120	391.0	28IG1@1|root,2Z8HJ@2|Bacteria,1G0EA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_29	1121377.KB906410_gene609	2.42e-92	321.0	COG4292@1|root,COG5207@1|root,COG4292@2|Bacteria,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	ltrA	-	-	ko:K03455,ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2,2.A.37	-	-	IRK,LtrA,zf-UBP
SRR25158343_k127_868515_7	485913.Krac_3213	4.871e-187	598.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158343_k127_868515_47	207954.MED92_11069	3.959e-61	215.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5U@1224|Proteobacteria,1SAZE@1236|Gammaproteobacteria,1XPKV@135619|Oceanospirillales	135619|Oceanospirillales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_33	378806.STAUR_5458	3.539e-85	292.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,42WB3@68525|delta/epsilon subdivisions,2WWR6@28221|Deltaproteobacteria,2YYFB@29|Myxococcales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158343_k127_868515_41	1459636.NTE_03091	1.314e-65	228.0	COG0431@1|root,arCOG04624@2157|Archaea,41T7Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
SRR25158343_k127_868515_24	1449076.JOOE01000001_gene2448	6.774e-111	366.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VFDU@28211|Alphaproteobacteria,2K48Y@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158343_k127_868515_12	102232.GLO73106DRAFT_00023900	1.058e-149	479.0	COG0657@1|root,COG0657@2|Bacteria,1G3P7@1117|Cyanobacteria	1117|Cyanobacteria	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158343_k127_868515_56	279714.FuraDRAFT_3523	1.297e-50	186.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158343_k127_868515_46	868864.Dester_0907	1.981e-61	217.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158343_k127_868515_64	1121289.JHVL01000002_gene2352	2.477e-44	170.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158343_k127_868515_66	1173264.KI913949_gene204	6.005e-41	158.0	28MW3@1|root,2ZB3G@2|Bacteria,1G2E1@1117|Cyanobacteria,1H8Z6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_38	1173264.KI913949_gene4371	1.046e-73	263.0	COG1630@1|root,COG1630@2|Bacteria,1G2J2@1117|Cyanobacteria,1HADT@1150|Oscillatoriales	1117|Cyanobacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR25158343_k127_868515_57	1499967.BAYZ01000163_gene6577	9.971e-50	182.0	COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158343_k127_868515_14	861299.J421_2513	2.649e-140	458.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158343_k127_868515_28	1144275.COCOR_01136	1.177e-92	316.0	COG2008@1|root,COG2008@2|Bacteria,1RBRU@1224|Proteobacteria,4302S@68525|delta/epsilon subdivisions,2WV77@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
SRR25158343_k127_868515_5	379066.GAU_0593	2.13e-188	600.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRR25158343_k127_868515_92	547144.HydHO_0028	4.304e-09	62.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_868515_2	700598.Niako_0113	0.0	1068.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1IR3G@117747|Sphingobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158343_k127_868515_6	1111479.AXAR01000001_gene354	2.777e-188	605.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,2785Q@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158343_k127_868515_69	1268068.PG5_15130	1.98e-39	153.0	COG4461@1|root,COG4461@2|Bacteria	2|Bacteria	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LprI
SRR25158343_k127_868515_25	392500.Swoo_1206	1.631e-107	353.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,1RPKU@1236|Gammaproteobacteria,2Q8Y0@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158343_k127_868515_27	1403819.BATR01000118_gene4111	1.348e-98	354.0	COG3264@1|root,COG3264@2|Bacteria,46T7X@74201|Verrucomicrobia,2IWP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158343_k127_868515_108	313595.P700755_002546	0.0006651	43.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia,4C318@83612|Psychroflexus	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158343_k127_868515_65	387093.SUN_0406	4.548e-44	169.0	COG4461@1|root,COG4461@2|Bacteria,1PFFH@1224|Proteobacteria,43ABM@68525|delta/epsilon subdivisions,2YR0C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
SRR25158343_k127_868515_90	102232.GLO73106DRAFT_00029150	2.162e-14	78.0	2E3TX@1|root,32YRB@2|Bacteria,1GQPR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_50	314292.VAS14_10569	3.927e-60	218.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZ89@1236|Gammaproteobacteria,1Y248@135623|Vibrionales	135623|Vibrionales	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158343_k127_868515_81	113355.CM001775_gene773	1.798e-21	100.0	2DKZK@1|root,310GY@2|Bacteria,1G6D3@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3011
SRR25158343_k127_868515_11	1382359.JIAL01000001_gene2707	8.4e-168	535.0	COG0183@1|root,COG0183@2|Bacteria,3Y2U4@57723|Acidobacteria,2JIS1@204432|Acidobacteriia	204432|Acidobacteriia	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158343_k127_868515_15	102129.Lepto7375DRAFT_1173	1.288e-139	454.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria,1H96B@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158343_k127_868515_48	1120980.JQKH01000009_gene1421	9.388e-61	213.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,2KR3G@206351|Neisseriales	206351|Neisseriales	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158343_k127_868515_34	439235.Dalk_3095	2.197e-84	283.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158343_k127_868515_62	1038860.AXAP01000007_gene6022	4.742e-45	168.0	COG1432@1|root,COG1432@2|Bacteria,1RJI8@1224|Proteobacteria	1224|Proteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158343_k127_868515_53	1502852.FG94_04119	1.083e-56	205.0	COG0637@1|root,COG0637@2|Bacteria,1MX3R@1224|Proteobacteria,2WGNJ@28216|Betaproteobacteria,475HR@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158343_k127_868515_30	666681.M301_1823	6.007e-90	302.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,2VJTM@28216|Betaproteobacteria,2KNKJ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
SRR25158343_k127_868515_26	666681.M301_2735	5.202e-101	335.0	COG4705@1|root,COG4705@2|Bacteria,1MVMJ@1224|Proteobacteria,2VJTM@28216|Betaproteobacteria,2KNKJ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Repeat of Unknown Function (DUF347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF347
SRR25158343_k127_868515_93	796606.BMMGA3_09330	4.448e-08	58.0	2EJIK@1|root,33D9H@2|Bacteria,1VKCQ@1239|Firmicutes,4HR92@91061|Bacilli,1ZIHV@1386|Bacillus	91061|Bacilli	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRR25158343_k127_868515_37	379066.GAU_2880	3.923e-75	269.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158343_k127_868515_36	234267.Acid_5477	2.777e-82	279.0	COG0745@1|root,COG0745@2|Bacteria,3Y522@57723|Acidobacteria	57723|Acidobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_868515_71	926549.KI421517_gene1149	8.258e-35	139.0	297E6@1|root,2ZUMN@2|Bacteria,4NPTI@976|Bacteroidetes,47R84@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158343_k127_868515_3	1121468.AUBR01000038_gene1965	1.094e-266	843.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia,42HW6@68295|Thermoanaerobacterales	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158343_k127_868515_103	998088.B565_1782	8.325e-05	55.0	COG1192@1|root,COG1192@2|Bacteria,1R5IJ@1224|Proteobacteria	1224|Proteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_96	1463820.JOGW01000014_gene447	1.08e-06	58.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158343_k127_868515_83	1308866.J416_15292	2.1e-19	93.0	2D7FD@1|root,32TNY@2|Bacteria,1VADP@1239|Firmicutes,4HKCW@91061|Bacilli,471VU@74385|Gracilibacillus	91061|Bacilli	S	Domain of unknown function (DUF1992)	ydhN1	-	-	-	-	-	-	-	-	-	-	-	DUF1992
SRR25158343_k127_868515_75	316275.VSAL_I1221	6.43e-28	119.0	COG3305@1|root,COG3305@2|Bacteria,1RKBI@1224|Proteobacteria,1S6AE@1236|Gammaproteobacteria,1XYMS@135623|Vibrionales	135623|Vibrionales	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
SRR25158343_k127_868515_39	1144275.COCOR_04876	7.474e-71	256.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria	1224|Proteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158343_k127_868515_43	357808.RoseRS_3801	3.172e-63	229.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158343_k127_868515_10	309807.SRU_2163	4.2e-172	559.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1FIQC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158343_k127_868515_77	204669.Acid345_4448	7.679e-27	122.0	COG1595@1|root,COG1595@2|Bacteria,3Y7TB@57723|Acidobacteria,2JMZD@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158343_k127_868515_106	401053.AciPR4_3867	0.0003843	49.0	COG5662@1|root,COG5662@2|Bacteria,3Y511@57723|Acidobacteria,2JK2E@204432|Acidobacteriia	204432|Acidobacteriia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158343_k127_868515_40	1347392.CCEZ01000016_gene2939	3.792e-69	241.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,36E7D@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
SRR25158343_k127_868515_100	1267535.KB906767_gene3275	2.208e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria,2JNRM@204432|Acidobacteriia	204432|Acidobacteriia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_868515_17	1340493.JNIF01000003_gene3549	3.993e-132	461.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_868515_98	160860.XP_007349263.1	4.808e-06	58.0	COG0013@1|root,KOG1155@2759|Eukaryota,38EMD@33154|Opisthokonta,3NU5Y@4751|Fungi,3UY4S@5204|Basidiomycota,22648@155619|Agaricomycetes,3H289@355688|Agaricomycetes incertae sedis	4751|Fungi	DO	TPR-like protein	cut23	GO:0000151,GO:0000152,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016567,GO:0019538,GO:0019941,GO:0030071,GO:0030163,GO:0030332,GO:0031145,GO:0031331,GO:0031461,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070647,GO:0071704,GO:0090068,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252	-	ko:K03355	ko04110,ko04111,ko04113,ko04114,ko04120,ko04914,ko05166,map04110,map04111,map04113,map04114,map04120,map04914,map05166	M00389	-	-	ko00000,ko00001,ko00002,ko03036,ko04121	-	-	-	ANAPC8,TPR_1,TPR_8
SRR25158343_k127_868515_13	1340493.JNIF01000003_gene3549	3.517e-147	505.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158343_k127_868515_35	1054460.SPPN_04715	4.543e-84	295.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli	91061|Bacilli	S	COG1078 HD superfamily phosphohydrolases	ywfO	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158343_k127_868515_94	483219.LILAB_04485	1.279e-07	63.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SRR25158343_k127_868515_58	1089550.ATTH01000001_gene2218	4.601e-48	181.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158343_k127_868515_4	926549.KI421517_gene2964	2.176e-198	638.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158343_k127_868515_88	543632.JOJL01000001_gene7548	2.268e-15	81.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4DEUJ@85008|Micromonosporales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158343_k127_868515_0	234267.Acid_5456	0.0	1941.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158343_k127_868515_1	204669.Acid345_4676	0.0	1877.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria,2JIQM@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158343_k127_868515_60	1123325.JHUV01000003_gene1576	5.68e-47	172.0	COG0222@1|root,COG0222@2|Bacteria,2G42K@200783|Aquificae	200783|Aquificae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158343_k127_868515_68	240015.ACP_2926	1.015e-40	156.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria,2JJ81@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158343_k127_868515_31	1121920.AUAU01000017_gene1254	2.57e-88	296.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria	57723|Acidobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158343_k127_868515_45	637390.AFOH01000118_gene328	1.172e-61	215.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,2NCW7@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158343_k127_868515_52	204669.Acid345_4681	6.013e-57	203.0	COG0250@1|root,COG0250@2|Bacteria,3Y3ZR@57723|Acidobacteria,2JHU8@204432|Acidobacteriia	204432|Acidobacteriia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158343_k127_868515_104	1207063.P24_18349	0.0001125	48.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2JTWP@204441|Rhodospirillales	204441|Rhodospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158343_k127_868515_87	269799.Gmet_0612	9.72e-17	80.0	COG0267@1|root,COG0267@2|Bacteria,1NJ67@1224|Proteobacteria,42V5X@68525|delta/epsilon subdivisions,2WSIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158343_k127_868515_86	1340493.JNIF01000003_gene3205	1e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria	57723|Acidobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158343_k127_894430_136	1173022.Cri9333_2401	8.041e-12	66.0	COG2337@1|root,COG2337@2|Bacteria,1G5S4@1117|Cyanobacteria,1HBT3@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158343_k127_894430_132	1078085.HMPREF1210_00659	1.997e-15	82.0	2E0S4@1|root,32WA4@2|Bacteria,1VCC7@1239|Firmicutes,4HKRB@91061|Bacilli,26I15@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_1	502025.Hoch_3248	0.0	1251.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158343_k127_894430_20	1123073.KB899242_gene1567	7.97e-168	538.0	2DBJC@1|root,2Z9K5@2|Bacteria,1NQYW@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 47	-	-	3.2.1.113	ko:K01230	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00073,M00074	R05982,R06722	-	ko00000,ko00001,ko00002,ko01000,ko04131	-	GH47	-	Glyco_hydro_47
SRR25158343_k127_894430_0	760117.JN27_15985	0.0	1372.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158343_k127_894430_55	290397.Adeh_1164	2.03e-83	288.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
SRR25158343_k127_894430_18	861299.J421_1510	1.119e-178	574.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158343_k127_894430_150	1288079.AUKN01000019_gene2766	0.0001669	51.0	2E6DR@1|root,3311A@2|Bacteria,2IKTW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_46	1210884.HG799474_gene15172	4.927e-96	329.0	COG2355@1|root,COG2355@2|Bacteria,2IXYG@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158343_k127_894430_14	118163.Ple7327_1970	4.245e-191	636.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3VMAA@52604|Pleurocapsales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9
SRR25158343_k127_894430_8	1047013.AQSP01000121_gene2697	3.818e-263	833.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158343_k127_894430_72	661478.OP10G_3900	2.235e-67	241.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158343_k127_894430_40	504472.Slin_4173	4.728e-110	370.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158343_k127_894430_47	243231.GSU2316	2.495e-95	323.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,43S51@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
SRR25158343_k127_894430_49	204669.Acid345_0136	8.517e-92	308.0	COG1521@1|root,COG1521@2|Bacteria,3Y398@57723|Acidobacteria,2JI76@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158343_k127_894430_98	1499968.TCA2_2528	3.848e-44	170.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158343_k127_894430_45	1296416.JACB01000015_gene4813	2.691e-98	330.0	COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,1HYNH@117743|Flavobacteriia,2YHUU@290174|Aquimarina	976|Bacteroidetes	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158343_k127_894430_19	1406840.Q763_08415	2.443e-171	546.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,1HXXC@117743|Flavobacteriia,2NUET@237|Flavobacterium	976|Bacteroidetes	S	Sulfatase maturase	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR25158343_k127_894430_140	269797.Mbar_A1824	1.638e-09	69.0	COG5635@1|root,arCOG02967@2157|Archaea,arCOG06747@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NARR@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
SRR25158343_k127_894430_7	1121459.AQXE01000016_gene37	6.097e-276	874.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2M9Q4@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158343_k127_894430_81	1242864.D187_000505	1.443e-57	226.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158343_k127_894430_124	1348663.KCH_74750	4.618e-24	119.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,2M588@2063|Kitasatospora	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
SRR25158343_k127_894430_121	1173029.JH980292_gene1820	2.034e-25	121.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_1,TPR_11,TPR_2,TPR_8
SRR25158343_k127_894430_113	1031288.AXAA01000001_gene2245	1.121e-33	151.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158343_k127_894430_30	251229.Chro_4009	3.279e-130	453.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SRR25158343_k127_894430_122	511051.CSE_09940	2.069e-25	113.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
SRR25158343_k127_894430_74	1128421.JAGA01000003_gene3171	1.334e-65	237.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
SRR25158343_k127_894430_139	1232410.KI421412_gene441	1.175e-09	63.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
SRR25158343_k127_894430_91	1121897.AUGO01000013_gene3229	2.732e-48	186.0	COG0627@1|root,COG0627@2|Bacteria,4NE7D@976|Bacteroidetes,1HYRB@117743|Flavobacteriia,2NT0U@237|Flavobacterium	976|Bacteroidetes	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158343_k127_894430_110	215803.DB30_8095	2.585e-36	142.0	2E3R3@1|root,32YNW@2|Bacteria,1N9P4@1224|Proteobacteria,432YQ@68525|delta/epsilon subdivisions,2WXU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_60	204669.Acid345_2060	1.526e-80	275.0	COG0483@1|root,COG0483@2|Bacteria,3Y3GD@57723|Acidobacteria,2JHRB@204432|Acidobacteriia	204432|Acidobacteriia	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158343_k127_894430_42	1267535.KB906767_gene1747	4.368e-100	333.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158343_k127_894430_92	1121286.AUMT01000002_gene1298	1.014e-46	172.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,3ZS40@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SRR25158343_k127_894430_66	1340493.JNIF01000003_gene2986	1.916e-76	273.0	COG0285@1|root,COG0285@2|Bacteria,3Y3ZA@57723|Acidobacteria	57723|Acidobacteria	H	Mur ligase, middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158343_k127_894430_37	194439.CT0399	1.099e-114	374.0	COG0588@1|root,COG0588@2|Bacteria,1FDHF@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158343_k127_894430_86	1307759.JOMJ01000004_gene2828	1.086e-52	195.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
SRR25158343_k127_894430_2	234267.Acid_7263	0.0	1196.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158343_k127_894430_80	234267.Acid_1035	1.129e-57	210.0	COG0463@1|root,COG0463@2|Bacteria,3Y982@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158343_k127_894430_50	1121920.AUAU01000007_gene408	2.087e-89	315.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158343_k127_894430_22	1169144.KB910946_gene3669	6.206e-155	504.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158343_k127_894430_152	682795.AciX8_4716	0.0004293	46.0	2EN0M@1|root,33FNU@2|Bacteria,3Y60X@57723|Acidobacteria,2JJZX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_118	1192034.CAP_6755	1.555e-27	116.0	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,42VKR@68525|delta/epsilon subdivisions,2WS4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158343_k127_894430_87	234267.Acid_6711	6.424e-50	184.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,DUF4833
SRR25158343_k127_894430_123	1382359.JIAL01000001_gene2418	2.213e-25	117.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria,2JIRN@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_894430_100	1340493.JNIF01000003_gene3663	7.021e-43	162.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria	57723|Acidobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158343_k127_894430_36	1128421.JAGA01000003_gene2902	1.367e-115	383.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	iJN678.pfkA	PFK
SRR25158343_k127_894430_41	429009.Adeg_0968	7.545e-105	353.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
SRR25158343_k127_894430_135	1449338.JQLU01000005_gene3476	1.021e-14	83.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UZ12@1239|Firmicutes,4HCUD@91061|Bacilli,27I1P@186828|Carnobacteriaceae	91061|Bacilli	M	NlpC/P60 family	usp	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP,NLPC_P60
SRR25158343_k127_894430_109	1379270.AUXF01000003_gene3855	1.199e-36	141.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158343_k127_894430_3	234267.Acid_0759	2.295e-320	1010.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,Peptidase_S9
SRR25158343_k127_894430_39	316274.Haur_0326	4.512e-110	366.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,374U8@32061|Chloroflexia	32061|Chloroflexia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158343_k127_894430_65	1444712.BN1013_01420	1.085e-76	263.0	COG0221@1|root,COG0221@2|Bacteria,2JFXQ@204428|Chlamydiae	204428|Chlamydiae	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158343_k127_894430_102	246197.MXAN_6341	8.086e-41	164.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158343_k127_894430_75	945713.IALB_0025	2.318e-65	236.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	ypdA	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
SRR25158343_k127_894430_67	204669.Acid345_3062	8.738e-75	274.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria,2JMNJ@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158343_k127_894430_57	234267.Acid_1101	1.198e-82	280.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158343_k127_894430_13	266117.Rxyl_1110	1.52e-197	625.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158343_k127_894430_115	234267.Acid_1496	8.337e-32	132.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria	57723|Acidobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158343_k127_894430_25	204669.Acid345_0704	3.796e-149	481.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158343_k127_894430_17	1382359.JIAL01000001_gene2977	9.426e-183	597.0	COG0539@1|root,COG0539@2|Bacteria,3Y3DA@57723|Acidobacteria,2JHS3@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158343_k127_894430_117	234267.Acid_4299	2.312e-29	119.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria	57723|Acidobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158343_k127_894430_84	234267.Acid_4300	2.957e-55	198.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158343_k127_894430_53	457570.Nther_1199	3.66e-85	312.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia	186801|Clostridia	O	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158343_k127_894430_27	644282.Deba_1726	2.496e-144	476.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158343_k127_894430_56	204669.Acid345_2141	4.749e-83	288.0	COG2133@1|root,COG2133@2|Bacteria,3Y98P@57723|Acidobacteria,2JP56@204432|Acidobacteriia	204432|Acidobacteriia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_63	234267.Acid_3254	1.829e-77	274.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158343_k127_894430_129	264732.Moth_0638	1.321e-17	99.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158343_k127_894430_105	1121428.DESHY_40225___1	2.512e-39	158.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,261DG@186807|Peptococcaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
SRR25158343_k127_894430_104	204669.Acid345_3367	1.483e-39	153.0	COG0735@1|root,COG0735@2|Bacteria,3Y4W6@57723|Acidobacteria,2JJH1@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158343_k127_894430_141	314271.RB2654_04944	5.542e-09	65.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	metal-binding protein	nqrF	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRR25158343_k127_894430_38	234267.Acid_1567	4.257e-114	381.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158343_k127_894430_119	1122164.JHWF01000030_gene2324	1.043e-26	122.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria,1SGBD@1236|Gammaproteobacteria,1JCCV@118969|Legionellales	118969|Legionellales	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
SRR25158343_k127_894430_131	1437425.CSEC_2049	9.368e-17	86.0	COG1777@1|root,COG1777@2|Bacteria,2JG25@204428|Chlamydiae	204428|Chlamydiae	K	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_44	661478.OP10G_0723	7.348e-99	332.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158343_k127_894430_93	1267535.KB906767_gene4070	2.247e-46	179.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
SRR25158343_k127_894430_88	861299.J421_4343	7.595e-50	183.0	COG0262@1|root,COG0262@2|Bacteria,1ZU5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158343_k127_894430_130	1210884.HG799466_gene12434	1.829e-17	91.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,AraC_binding,DJ-1_PfpI,HTH_18,HTH_AraC
SRR25158343_k127_894430_23	1121904.ARBP01000007_gene2939	2.596e-153	500.0	COG0362@1|root,COG0362@2|Bacteria,4NG05@976|Bacteroidetes,47NDJ@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158343_k127_894430_125	1178825.ALIH01000002_gene940	1.61e-23	108.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158343_k127_894430_6	1123508.JH636439_gene1277	8.485e-280	880.0	COG0243@1|root,COG0243@2|Bacteria,2IXVV@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SRR25158343_k127_894430_133	445961.IW15_16350	5.975e-15	79.0	2E6K6@1|root,3316Y@2|Bacteria,4NT3A@976|Bacteroidetes,1I409@117743|Flavobacteriia,3ZSDK@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_62	1121957.ATVL01000011_gene3572	3.591e-79	274.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158343_k127_894430_54	1123073.KB899241_gene3101	9.363e-84	285.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XCBQ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_894430_52	1117379.BABA_00490	1.934e-86	294.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus	91061|Bacilli	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158343_k127_894430_120	1160718.SU9_02429	6.392e-26	122.0	28HEJ@1|root,2Z7QZ@2|Bacteria,2I8GI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185,DUF5005
SRR25158343_k127_894430_11	1254432.SCE1572_31475	1.076e-217	680.0	COG4948@1|root,COG4948@2|Bacteria,1NI9F@1224|Proteobacteria,435N4@68525|delta/epsilon subdivisions,2X01C@28221|Deltaproteobacteria,2Z1AH@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158343_k127_894430_35	204669.Acid345_0640	7.925e-117	383.0	COG0657@1|root,COG0657@2|Bacteria,3Y44Z@57723|Acidobacteria,2JJYN@204432|Acidobacteriia	204432|Acidobacteriia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158343_k127_894430_21	391037.Sare_3007	3.216e-165	545.0	COG3408@1|root,COG3408@2|Bacteria,2H31J@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_94	1267535.KB906767_gene4363	1.791e-45	190.0	COG0383@1|root,COG0383@2|Bacteria,3Y77D@57723|Acidobacteria,2JKQ2@204432|Acidobacteriia	204432|Acidobacteriia	G	Polysaccharide lyase family 4, domain III	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
SRR25158343_k127_894430_15	204669.Acid345_0638	4.665e-188	626.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HY@57723|Acidobacteria,2JIYZ@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_894430_78	1040986.ATYO01000001_gene1592	1.825e-63	230.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158343_k127_894430_69	1267535.KB906767_gene1722	1.002e-68	242.0	COG1028@1|root,COG1028@2|Bacteria,3Y7GE@57723|Acidobacteria,2JM48@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158343_k127_894430_34	1128912.GMES_3105	6.695e-117	398.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,1S0S6@1236|Gammaproteobacteria,46A7Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158343_k127_894430_107	999419.HMPREF1077_01323	9.988e-38	153.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia,2304Q@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158343_k127_894430_32	1267535.KB906767_gene3747	3.091e-125	413.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria,2JIYY@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158343_k127_894430_146	684949.ATTJ01000002_gene152	1.374e-05	53.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	legA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Ank_2,Ank_4,Peptidase_M48
SRR25158343_k127_894430_83	234267.Acid_1127	1.325e-55	200.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158343_k127_894430_31	1183438.GKIL_2901	2.346e-125	430.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_2901|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158343_k127_894430_151	7370.XP_005182854.1	0.0002133	52.0	COG1525@1|root,KOG2039@2759|Eukaryota,38HTP@33154|Opisthokonta,3BB9N@33208|Metazoa,3CV4Y@33213|Bilateria,41V3D@6656|Arthropoda,3SI77@50557|Insecta,44Z90@7147|Diptera	33208|Metazoa	K	It is involved in the biological process described with gene silencing by RNA	SND1	GO:0000003,GO:0003674,GO:0003712,GO:0003713,GO:0003824,GO:0004518,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010528,GO:0010529,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016441,GO:0016442,GO:0016458,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022414,GO:0031047,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031332,GO:0032501,GO:0032504,GO:0032991,GO:0034641,GO:0034655,GO:0035194,GO:0035195,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045935,GO:0046483,GO:0046700,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097433,GO:0140110,GO:1901360,GO:1901361,GO:1901575,GO:1902680,GO:1903506,GO:1903508,GO:1990904,GO:2001141	-	ko:K13221,ko:K15979	ko05169,ko05203,map05169,map05203	-	-	-	ko00000,ko00001,ko03041	-	-	-	SNase,TUDOR
SRR25158343_k127_894430_143	756067.MicvaDRAFT_4267	6.159e-08	60.0	COG3170@1|root,COG3170@2|Bacteria,1G596@1117|Cyanobacteria,1HBZQ@1150|Oscillatoriales	1117|Cyanobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_61	1267533.KB906733_gene3362	1.818e-79	287.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158343_k127_894430_64	937777.Deipe_2119	7.111e-77	265.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158343_k127_894430_58	1382359.JIAL01000001_gene1276	2.898e-82	282.0	COG0774@1|root,COG0774@2|Bacteria,3Y40I@57723|Acidobacteria,2JI1R@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
SRR25158343_k127_894430_103	313612.L8106_26062	1.562e-40	161.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria,1H7Z3@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRR25158343_k127_894430_89	926549.KI421517_gene500	5.686e-49	177.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,47QAF@768503|Cytophagia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR25158343_k127_894430_43	383372.Rcas_1801	2.328e-99	340.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi,3754D@32061|Chloroflexia	32061|Chloroflexia	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158343_k127_894430_112	234267.Acid_3749	2.505e-34	141.0	29B3X@1|root,2ZY2J@2|Bacteria,3Y92X@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158343_k127_894430_128	639030.JHVA01000001_gene2680	3.306e-20	102.0	29B3X@1|root,2ZY2J@2|Bacteria,3Y92X@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158343_k127_894430_96	234267.Acid_3750	2.655e-44	167.0	COG1131@1|root,COG1131@2|Bacteria,3Y50U@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_894430_101	639030.JHVA01000001_gene2679	4.385e-41	158.0	COG1131@1|root,COG1131@2|Bacteria,3Y50U@57723|Acidobacteria,2JM9C@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_894430_116	639030.JHVA01000001_gene2678	1.549e-31	127.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria,2JK5T@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158343_k127_894430_111	234267.Acid_1190	1.352e-34	141.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158343_k127_894430_9	861299.J421_3346	2.239e-226	712.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158343_k127_894430_26	1123008.KB905700_gene2139	1.179e-144	470.0	COG1680@1|root,COG1680@2|Bacteria,4PHZD@976|Bacteroidetes,2G1GG@200643|Bacteroidia,2312Z@171551|Porphyromonadaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_894430_126	395961.Cyan7425_0091	9.232e-23	101.0	COG0662@1|root,COG0662@2|Bacteria,1GEZS@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158343_k127_894430_106	880073.Calab_0535	1.253e-38	151.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158343_k127_894430_76	313595.P700755_003529	3.283e-64	227.0	28JH1@1|root,2Z9AM@2|Bacteria,4NJYJ@976|Bacteroidetes,1I0ZC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_148	1502851.FG93_02494	3.948e-05	52.0	2ER1C@1|root,33IKW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_85	309807.SRU_1476	4.045e-55	202.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,1FIVI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158343_k127_894430_4	1123276.KB893247_gene178	1.115e-316	985.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
SRR25158343_k127_894430_90	452637.Oter_3517	2.498e-48	189.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158343_k127_894430_95	880073.Calab_1746	2.46e-45	166.0	2CIU6@1|root,32S8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_99	215803.DB30_7158	6.853e-43	164.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WQUD@28221|Deltaproteobacteria,2YVF3@29|Myxococcales	28221|Deltaproteobacteria	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158343_k127_894430_12	861299.J421_3345	4.016e-201	634.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158343_k127_894430_82	370438.PTH_1362	9.941e-57	200.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158343_k127_894430_68	1249997.JHZW01000003_gene3139	5.023e-73	256.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,1HX0M@117743|Flavobacteriia,2PIFJ@252356|Maribacter	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158343_k127_894430_5	929703.KE386491_gene1900	3.454e-283	883.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47JV2@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
SRR25158343_k127_894430_79	1121957.ATVL01000006_gene3165	5.671e-60	210.0	COG0454@1|root,COG0456@2|Bacteria,4NQ7Z@976|Bacteroidetes,47QG5@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158343_k127_894430_147	1144313.PMI10_03218	2.72e-05	47.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,1I213@117743|Flavobacteriia,2NT1W@237|Flavobacterium	976|Bacteroidetes	S	Bacteriocin-protection protein	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158343_k127_894430_51	1454007.JAUG01000012_gene2442	3.02e-87	306.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158343_k127_894430_10	204669.Acid345_1454	8.387e-222	701.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158343_k127_894430_108	247490.KSU1_C0427	2.775e-37	152.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158343_k127_894430_144	1173022.Cri9333_0457	6.74e-08	61.0	290V7@1|root,2ZNH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_29	880072.Desac_0330	2.051e-132	436.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158343_k127_894430_70	1340493.JNIF01000003_gene3892	1.243e-68	261.0	COG1452@1|root,COG1452@2|Bacteria,3Y37B@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
SRR25158343_k127_894430_24	272134.KB731324_gene981	1.111e-152	499.0	28H9S@1|root,2Z7ME@2|Bacteria,1G53B@1117|Cyanobacteria,1HAD7@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
SRR25158343_k127_894430_77	929556.Solca_0274	9.592e-64	225.0	COG3179@1|root,COG3179@2|Bacteria,4NQZS@976|Bacteroidetes,1IYFN@117747|Sphingobacteriia	976|Bacteroidetes	S	Chitinase class I	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_19
SRR25158343_k127_894430_149	1121104.AQXH01000001_gene1191	6.228e-05	55.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	BBP2,MucBP,Porin_4,SLH
SRR25158343_k127_894430_33	204669.Acid345_0712	5.793e-122	399.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria,2JI58@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158343_k127_894430_59	1499967.BAYZ01000178_gene4651	1.054e-80	283.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158343_k127_894430_71	926549.KI421517_gene2917	1.589e-68	240.0	COG4572@1|root,COG4572@2|Bacteria,4PM1W@976|Bacteroidetes,47XZW@768503|Cytophagia	976|Bacteroidetes	S	Cation transport regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_894430_73	331678.Cphamn1_0934	1.128e-66	244.0	COG0373@1|root,COG0373@2|Bacteria,1FDBA@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158343_k127_894430_48	401526.TcarDRAFT_0742	4.631e-93	315.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158343_k127_894430_137	1408433.JHXV01000008_gene225	3.126e-10	70.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia,2PA6W@246874|Cryomorphaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRR25158343_k127_894430_28	1191523.MROS_0609	3.104e-134	436.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3734,iSBO_1134.SBO_4018	URO-D
SRR25158343_k127_894430_16	945713.IALB_0538	6.597e-183	582.0	COG0635@1|root,COG0635@2|Bacteria	2|Bacteria	H	coproporphyrinogen oxidase activity	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	HemN_C,Radical_SAM
SRR25158343_k127_894430_97	179408.Osc7112_1665	3.139e-44	166.0	COG0276@1|root,COG0276@2|Bacteria,1G1UI@1117|Cyanobacteria,1H74W@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Chloroa_b-bind,Ferrochelatase
SRR25158343_k127_924198_50	1191523.MROS_0607	6.076e-92	315.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515	Ferrochelatase
SRR25158343_k127_924198_47	880073.Calab_3717	1.629e-98	337.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
SRR25158343_k127_924198_66	1041142.ATTP01000015_gene6738	1.146e-69	244.0	COG0388@1|root,COG0388@2|Bacteria,1NMSE@1224|Proteobacteria,2VDME@28211|Alphaproteobacteria,4BBRJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158343_k127_924198_25	340099.Teth39_1889	9.667e-140	450.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
SRR25158343_k127_924198_18	358681.BBR47_18060	1.517e-173	554.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
SRR25158343_k127_924198_62	1121405.dsmv_3027	4.943e-75	262.0	COG3016@1|root,COG3016@2|Bacteria,1QHS4@1224|Proteobacteria,4315A@68525|delta/epsilon subdivisions,2WW96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
SRR25158343_k127_924198_119	331678.Cphamn1_0017	2.081e-16	85.0	COG0792@1|root,COG0792@2|Bacteria,1FE8E@1090|Chlorobi	1090|Chlorobi	J	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158343_k127_924198_101	985255.APHJ01000019_gene737	1.165e-33	135.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I28K@117743|Flavobacteriia,2P7ST@244698|Gillisia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SRR25158343_k127_924198_131	531844.FIC_00631	2.645e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,4NME3@976|Bacteroidetes,1I7J3@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
SRR25158343_k127_924198_60	224719.Abm4_1001	5.85e-77	267.0	COG0548@1|root,arCOG00862@2157|Archaea,2XTW9@28890|Euryarchaeota,23NS3@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158343_k127_924198_53	1163407.UU7_01712	7.579e-89	304.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1S7AW@1236|Gammaproteobacteria,1X35E@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158343_k127_924198_42	518766.Rmar_0947	5.037e-106	356.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158343_k127_924198_73	497964.CfE428DRAFT_4056	1.493e-57	207.0	COG2755@1|root,COG2755@2|Bacteria,46T12@74201|Verrucomicrobia	74201|Verrucomicrobia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158343_k127_924198_114	1121899.Q764_06450	4.766e-20	93.0	COG2388@1|root,COG2388@2|Bacteria,4NST0@976|Bacteroidetes,1I3YV@117743|Flavobacteriia,2NX90@237|Flavobacterium	976|Bacteroidetes	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158343_k127_924198_118	1267535.KB906767_gene3274	1.317e-16	85.0	2CIIF@1|root,30NI8@2|Bacteria,3Y8FJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_56	545243.BAEV01000039_gene1463	1.215e-81	284.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,36E3S@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158343_k127_924198_23	234267.Acid_7606	6.496e-143	492.0	COG1629@1|root,COG4771@2|Bacteria,3Y3YV@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158343_k127_924198_102	1382359.JIAL01000001_gene1850	3.291e-33	134.0	2ADDN@1|root,3133D@2|Bacteria,3Y4SX@57723|Acidobacteria,2JJFB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_133	247639.MGP2080_14009	1.386e-09	70.0	COG2128@1|root,COG2128@2|Bacteria,1PC51@1224|Proteobacteria,1RS2U@1236|Gammaproteobacteria,1J74C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158343_k127_924198_125	1210884.HG799464_gene10708	4.982e-13	81.0	COG2128@1|root,COG2128@2|Bacteria,2IYJK@203682|Planctomycetes	2|Bacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Glutaredoxin
SRR25158343_k127_924198_35	204669.Acid345_1712	2.273e-119	399.0	COG1680@1|root,COG1680@2|Bacteria,3Y3WB@57723|Acidobacteria,2JJDH@204432|Acidobacteriia	204432|Acidobacteriia	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158343_k127_924198_64	518766.Rmar_0949	3.06e-71	254.0	COG1763@1|root,COG1763@2|Bacteria,4PM6G@976|Bacteroidetes,1FK05@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_19	289377.HL41_03500	1.986e-172	548.0	COG0137@1|root,COG0137@2|Bacteria,2GGZY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158343_k127_924198_112	767817.Desgi_2597	8.003e-22	100.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158343_k127_924198_86	1121930.AQXG01000003_gene2645	9.153e-47	179.0	COG3176@1|root,COG3176@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
SRR25158343_k127_924198_65	518766.Rmar_1205	1.391e-70	246.0	COG3332@1|root,COG3332@2|Bacteria,4NMX4@976|Bacteroidetes,1FJ9F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRR25158343_k127_924198_40	382464.ABSI01000005_gene1401	1.376e-107	370.0	COG0189@1|root,COG0586@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,46UXZ@74201|Verrucomicrobia	74201|Verrucomicrobia	HJ	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158343_k127_924198_103	1250232.JQNJ01000001_gene3560	1.153e-32	131.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,1I3A8@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158343_k127_924198_116	382464.ABSI01000005_gene1399	4.59e-18	91.0	COG2318@1|root,COG2318@2|Bacteria,46WF2@74201|Verrucomicrobia,2IWE9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_85	861299.J421_1881	4.954e-47	177.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,PD40
SRR25158343_k127_924198_45	861299.J421_1875	4.238e-101	337.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
SRR25158343_k127_924198_15	861299.J421_1876	7.537e-184	589.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158343_k127_924198_69	118168.MC7420_8161	1.356e-65	230.0	COG0572@1|root,COG0572@2|Bacteria,1G67K@1117|Cyanobacteria,1HC0C@1150|Oscillatoriales	1117|Cyanobacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158343_k127_924198_78	234267.Acid_3141	1.108e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,3Y5J6@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_924198_21	861299.J421_1879	3.538e-164	527.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158343_k127_924198_143	321955.AAGP01000059_gene1411	0.0008138	45.0	COG5662@1|root,COG5662@2|Bacteria,2I5Y8@201174|Actinobacteria,4FAHN@85019|Brevibacteriaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158343_k127_924198_87	1116472.MGMO_177c00220	4.302e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,1XFI1@135618|Methylococcales	135618|Methylococcales	K	RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_924198_142	426117.M446_3934	0.0006584	46.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2UKDJ@28211|Alphaproteobacteria,1JYEB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158343_k127_924198_141	640510.BC1001_4770	0.0001746	48.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158343_k127_924198_55	864702.OsccyDRAFT_4593	1.182e-81	280.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria,1H9H5@1150|Oscillatoriales	1117|Cyanobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158343_k127_924198_6	861299.J421_1872	9.115e-250	780.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158343_k127_924198_32	211165.AJLN01000061_gene3947	2.022e-124	408.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158343_k127_924198_100	1333998.M2A_1149	1.285e-34	138.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,4BQUK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
SRR25158343_k127_924198_52	118173.KB235914_gene2349	7.644e-91	301.0	COG0431@1|root,COG0431@2|Bacteria,1G3AZ@1117|Cyanobacteria,1HAU3@1150|Oscillatoriales	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158343_k127_924198_2	671143.DAMO_0621	0.0	1359.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SRR25158343_k127_924198_88	671143.DAMO_1116	5.886e-46	178.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158343_k127_924198_20	251221.35211731	3.338e-168	535.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158343_k127_924198_26	204669.Acid345_0689	2.132e-136	445.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158343_k127_924198_14	63737.Npun_R2418	9.468e-189	595.0	COG1063@1|root,COG1063@2|Bacteria,1G26C@1117|Cyanobacteria,1HIG2@1161|Nostocales	1117|Cyanobacteria	E	Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158343_k127_924198_70	1173022.Cri9333_2459	1.675e-64	229.0	COG5637@1|root,COG5637@2|Bacteria,1G2FS@1117|Cyanobacteria,1H9BE@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158343_k127_924198_36	1173024.KI912151_gene2147	4.484e-119	393.0	COG0300@1|root,COG0300@2|Bacteria,1G1AT@1117|Cyanobacteria,1JKU3@1189|Stigonemataceae	1117|Cyanobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_924198_28	357808.RoseRS_1582	4.529e-133	432.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	RMMBL
SRR25158343_k127_924198_12	1123508.JH636447_gene7801	1.387e-196	626.0	COG1793@1|root,COG1793@2|Bacteria,2IY9R@203682|Planctomycetes	203682|Planctomycetes	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158343_k127_924198_77	1267535.KB906767_gene3930	6.487e-51	201.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158343_k127_924198_11	1267211.KI669560_gene2369	9.639e-198	626.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158343_k127_924198_129	234267.Acid_0500	4.97e-11	70.0	2DR0H@1|root,339NS@2|Bacteria,3Y59F@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Caa(3)-type oxidase, subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158343_k127_924198_74	1128421.JAGA01000003_gene2879	1.212e-55	205.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158343_k127_924198_5	234267.Acid_0498	3.566e-261	814.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158343_k127_924198_46	234267.Acid_0497	4.397e-99	336.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
SRR25158343_k127_924198_126	234267.Acid_0495	9.634e-13	75.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_43	1128421.JAGA01000003_gene2874	1.125e-103	349.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_81	525904.Tter_1592	5.292e-48	179.0	COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158343_k127_924198_82	1128421.JAGA01000003_gene2872	1.252e-47	177.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SRR25158343_k127_924198_13	1128421.JAGA01000003_gene2871	1.786e-189	601.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SRR25158343_k127_924198_4	472759.Nhal_2603	0.0	1039.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
SRR25158343_k127_924198_57	1267535.KB906767_gene1582	1.325e-81	278.0	COG3880@1|root,COG3880@2|Bacteria,3Y2KG@57723|Acidobacteria,2JHTD@204432|Acidobacteriia	204432|Acidobacteriia	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SRR25158343_k127_924198_7	234267.Acid_7324	1.562e-232	732.0	COG0028@1|root,COG0028@2|Bacteria,3Y3QI@57723|Acidobacteria	57723|Acidobacteria	EH	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158343_k127_924198_75	525904.Tter_2124	1.636e-54	207.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
SRR25158343_k127_924198_48	485913.Krac_10321	4.033e-95	323.0	COG4948@1|root,COG4948@2|Bacteria,2G83T@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158343_k127_924198_90	1267533.KB906735_gene4526	1.601e-44	173.0	COG1295@1|root,COG1295@2|Bacteria,3Y3RZ@57723|Acidobacteria,2JIYV@204432|Acidobacteriia	204432|Acidobacteriia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158343_k127_924198_3	1123278.KB893387_gene4377	0.0	1266.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NJWD@976|Bacteroidetes,47NJ1@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158343_k127_924198_39	1123248.KB893326_gene1247	1.13e-115	379.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Hemerythrin,Rieske
SRR25158343_k127_924198_96	1121288.AULL01000018_gene1941	3.711e-37	143.0	2DD18@1|root,2ZG4B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_144	278963.ATWD01000001_gene2001	0.0008138	45.0	2FIH7@1|root,34A99@2|Bacteria,3Y8E3@57723|Acidobacteria,2JNKE@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_41	163908.KB235896_gene3107	4.168e-106	347.0	COG2132@1|root,COG2132@2|Bacteria,1GHJ9@1117|Cyanobacteria,1HTC3@1161|Nostocales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158343_k127_924198_106	1123368.AUIS01000005_gene413	1.054e-28	121.0	COG3652@1|root,COG3652@2|Bacteria,1N6QU@1224|Proteobacteria,1T0P2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4142
SRR25158343_k127_924198_71	1312959.KI914679_gene1954	8.12e-61	214.0	arCOG04511@1|root,329Z6@2|Bacteria,2GYB3@201174|Actinobacteria	201174|Actinobacteria	S	Fe2+ transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Iron_transport
SRR25158343_k127_924198_84	375286.mma_1955	3.309e-47	173.0	COG1661@1|root,COG1661@2|Bacteria,1RJC1@1224|Proteobacteria,2VXP3@28216|Betaproteobacteria,47560@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
SRR25158343_k127_924198_33	709986.Deima_1180	4.035e-124	408.0	COG0387@1|root,COG0387@2|Bacteria,1WJIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158343_k127_924198_24	497964.CfE428DRAFT_1182	5.88e-140	453.0	COG0300@1|root,COG0300@2|Bacteria,46TCZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158343_k127_924198_16	1040983.AXAE01000013_gene5806	1.765e-182	582.0	COG3664@1|root,COG3664@2|Bacteria,1MWYX@1224|Proteobacteria,2U4D0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 39	xynB	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
SRR25158343_k127_924198_17	1320556.AVBP01000001_gene4641	6.48e-176	561.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,2U1B2@28211|Alphaproteobacteria,43RF4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
SRR25158343_k127_924198_0	857087.Metme_2224	0.0	2659.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XDIT@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SRR25158343_k127_924198_145	118005.AWNK01000006_gene1283	0.0008169	51.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158343_k127_924198_128	237368.SCABRO_02261	1.197e-11	68.0	COG0582@1|root,COG0582@2|Bacteria,2J3PC@203682|Planctomycetes	203682|Planctomycetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158343_k127_924198_110	330214.NIDE0335	2.352e-22	111.0	COG0582@1|root,COG0582@2|Bacteria,3J133@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158343_k127_924198_117	570967.JMLV01000006_gene274	8.713e-18	85.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2UFXF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
SRR25158343_k127_924198_109	555779.Dthio_PD1883	2.271e-26	111.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria,2MDD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
SRR25158343_k127_924198_139	479437.Elen_0560	8.544e-05	47.0	COG1598@1|root,COG1598@2|Bacteria,2HTYK@201174|Actinobacteria,4CWFU@84998|Coriobacteriia	84998|Coriobacteriia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158343_k127_924198_134	1144275.COCOR_05058	5.198e-08	64.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158343_k127_924198_92	903818.KI912268_gene967	9.895e-40	156.0	COG0558@1|root,COG0558@2|Bacteria,3Y520@57723|Acidobacteria	57723|Acidobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158343_k127_924198_68	1519464.HY22_00520	8.303e-68	245.0	COG5621@1|root,COG5621@2|Bacteria	2|Bacteria	S	spheroidene biosynthetic process	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158343_k127_924198_136	401053.AciPR4_3582	4.551e-06	58.0	COG5662@1|root,COG5662@2|Bacteria,3Y4JS@57723|Acidobacteria,2JJ7U@204432|Acidobacteriia	204432|Acidobacteriia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158343_k127_924198_94	452637.Oter_3187	8.716e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,46U3X@74201|Verrucomicrobia,3K7M2@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_924198_135	234267.Acid_5362	1.85e-07	62.0	COG2976@1|root,COG2976@2|Bacteria,3Y9AW@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
SRR25158343_k127_924198_37	234267.Acid_3927	5.596e-117	389.0	COG0189@1|root,COG0189@2|Bacteria,3Y37D@57723|Acidobacteria	57723|Acidobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_122	1278073.MYSTI_06291	1.473e-14	84.0	2EDTI@1|root,337NU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_95	378806.STAUR_6365	1.565e-37	151.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria,438WP@68525|delta/epsilon subdivisions,2X9RW@28221|Deltaproteobacteria,2YY15@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158343_k127_924198_1	926550.CLDAP_00560	0.0	1748.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
SRR25158343_k127_924198_130	1122179.KB890436_gene1351	1.842e-10	70.0	COG5523@1|root,COG5523@2|Bacteria,4NVAK@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_108	1121015.N789_09315	1.671e-26	119.0	COG4319@1|root,COG4319@2|Bacteria,1PZUH@1224|Proteobacteria,1SUHF@1236|Gammaproteobacteria,1XBQN@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158343_k127_924198_31	1173026.Glo7428_1305	1.091e-125	410.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1G1R7@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR25158343_k127_924198_99	1123377.AUIV01000002_gene1158	2.979e-35	149.0	2AQ2A@1|root,31F7E@2|Bacteria,1QCMG@1224|Proteobacteria,1T8CS@1236|Gammaproteobacteria,1XAFU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_22	1173027.Mic7113_3665	1.264e-154	493.0	COG0667@1|root,COG0667@2|Bacteria,1G3RI@1117|Cyanobacteria,1HHEI@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158343_k127_924198_30	1341151.ASZU01000017_gene1764	3.722e-128	424.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,27BMY@186824|Thermoactinomycetaceae	91061|Bacilli	S	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158343_k127_924198_54	485913.Krac_6983	3.837e-88	309.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	AhpC-TSA,MauE
SRR25158343_k127_924198_34	411477.PARMER_02193	1.442e-120	398.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,2FMUM@200643|Bacteroidia,22VYI@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158343_k127_924198_120	572480.Arnit_0651	2.101e-16	83.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2YPSE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Preprotein translocase	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158343_k127_924198_44	1267533.KB906734_gene4325	1.24e-103	357.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria,2JHJC@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158343_k127_924198_67	1198114.AciX9_3623	7.011e-68	245.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158343_k127_924198_127	1340493.JNIF01000003_gene1849	5.084e-12	76.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158343_k127_924198_61	234267.Acid_1281	3.235e-75	260.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR25158343_k127_924198_115	639030.JHVA01000001_gene2639	4.999e-19	92.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria,2JJKY@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158343_k127_924198_124	204669.Acid345_0151	2.56e-13	76.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria,2JJQV@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158343_k127_924198_137	204669.Acid345_0152	1.423e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria,2JISD@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158343_k127_924198_8	234267.Acid_1285	4.353e-227	725.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria	57723|Acidobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158343_k127_924198_80	70601.3257265	1.594e-49	179.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158343_k127_924198_111	1379281.AVAG01000065_gene1170	7.701e-22	96.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MD8Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158343_k127_924198_123	370438.PTH_0118	5.026e-14	84.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,266W1@186807|Peptococcaceae	186801|Clostridia	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158343_k127_924198_29	1288.SXYLSMQ121_0860	5.082e-132	444.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,4GXXM@90964|Staphylococcaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158343_k127_924198_105	1340493.JNIF01000003_gene4460	2.933e-29	128.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158343_k127_924198_10	398767.Glov_1900	2.512e-203	643.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158343_k127_924198_121	717605.Theco_2032	8.213e-15	84.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,26SDE@186822|Paenibacillaceae	91061|Bacilli	S	Helix-turn-helix domain	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
SRR25158343_k127_924198_93	926569.ANT_07230	3.887e-38	146.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
SRR25158343_k127_924198_27	517418.Ctha_1060	2.099e-135	451.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	eutE	-	1.2.1.10	ko:K00132	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158343_k127_924198_107	891968.Anamo_0112	2.713e-28	117.0	COG4577@1|root,COG4577@2|Bacteria,3TB6U@508458|Synergistetes	508458|Synergistetes	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
SRR25158343_k127_924198_91	1267535.KB906767_gene623	3.852e-41	166.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_924198_63	926566.Terro_3400	4.414e-73	258.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158343_k127_924198_97	1047013.AQSP01000139_gene2410	8.423e-36	143.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158343_k127_924198_138	350688.Clos_1205	4.21e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes	1239|Firmicutes	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
SRR25158343_k127_924198_89	1340493.JNIF01000003_gene4118	1.321e-45	181.0	COG0250@1|root,COG0250@2|Bacteria,3Y3I1@57723|Acidobacteria	57723|Acidobacteria	K	Participates in transcription elongation, termination and antitermination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_9	1340493.JNIF01000003_gene3519	1.706e-216	707.0	COG1629@1|root,COG4771@2|Bacteria,3Y3HA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158343_k127_924198_72	234267.Acid_0903	3.266e-60	213.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158343_k127_924198_51	1232410.KI421418_gene2263	1.07e-91	308.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158343_k127_924198_58	717605.Theco_2070	1.182e-80	275.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,26QD1@186822|Paenibacillaceae	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158343_k127_924198_49	1382359.JIAL01000001_gene1355	9.596e-95	320.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158343_k127_924198_79	234267.Acid_0907	1.534e-50	182.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158343_k127_924198_76	240015.ACP_2944	2.237e-53	192.0	COG0102@1|root,COG0102@2|Bacteria,3Y4U5@57723|Acidobacteria,2JJGG@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158343_k127_924198_38	234267.Acid_1509	5.827e-116	391.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_98	1354300.AUQY01000002_gene1129	2.008e-35	141.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,22HGQ@1570339|Peptoniphilaceae	186801|Clostridia	L	Hydrolase, NUDIX family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158343_k127_924198_59	197221.22295627	7.877e-80	277.0	COG1131@1|root,COG1131@2|Bacteria,1G0UC@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158343_k127_924198_104	204669.Acid345_1573	1.3e-32	139.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158343_k127_924198_83	204669.Acid345_1572	2.684e-47	180.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158343_k127_924198_132	945713.IALB_0677	8.537e-10	72.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
## 4020 queries scanned
## Total time (seconds): 20.149406909942627
## Rate: 199.51 q/s