## Sun Dec 14 12:28:20 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158347_bin.44.fa -m mmseqs --itype genome -o SRR25158347_bin.44 --output_dir /data/result/bins/wyx/egg/SRR25158347_bin.44 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158347_k127_1006926_15	1112204.GPOL_c07110	1.899e-08	57.0	COG2963@1|root,COG2963@2|Bacteria,2IMG6@201174|Actinobacteria,4GENJ@85026|Gordoniaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
SRR25158347_k127_1006926_2	1120949.KB903315_gene135	1.526e-81	279.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4DDJR@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158347_k127_1006926_8	1068980.ARVW01000001_gene2814	2.367e-36	143.0	COG4308@1|root,COG4308@2|Bacteria,2IN4A@201174|Actinobacteria,4E4Z1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	ephG	GO:0003674,GO:0003824,GO:0004301,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016801,GO:0016803,GO:0018904,GO:0033963,GO:0044237,GO:0044281,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0097176,GO:1901360	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
SRR25158347_k127_1006926_0	1386089.N865_16515	0.0	1186.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4FG7V@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_1006926_9	471853.Bcav_1407	6.939e-36	141.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158347_k127_1006926_3	502025.Hoch_5114	2.534e-74	265.0	28XBK@1|root,2ZJ9G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1006926_10	43354.JOIJ01000003_gene3828	1.62e-33	139.0	2F439@1|root,33WUU@2|Bacteria,2IDQW@201174|Actinobacteria,4E6FS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1006926_1	1122138.AQUZ01000017_gene6596	2.538e-260	825.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4DR7N@85009|Propionibacteriales	201174|Actinobacteria	E	GMC oxidoreductase	choD_2	-	1.1.1.400	ko:K20927	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
SRR25158347_k127_1006926_16	1123519.PSJM300_12915	2.415e-06	59.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1Z0QF@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
SRR25158347_k127_1006926_7	1157632.AQWQ01000013_gene2731	1.571e-36	156.0	COG0346@1|root,COG0346@2|Bacteria,2I8Q5@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1006926_14	1449976.KALB_6980	2.536e-13	78.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E3MG@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
SRR25158347_k127_1006926_11	298653.Franean1_4861	4.493e-30	134.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158347_k127_1006926_12	710686.Mycsm_04583	4.445e-24	106.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_1006926_5	479434.Sthe_2248	1.146e-41	158.0	COG2373@1|root,COG2373@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia	189775|Thermomicrobia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1006926_6	1298863.AUEP01000022_gene1862	1.993e-38	145.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria,4DV53@85009|Propionibacteriales	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158347_k127_1006926_4	35754.JNYJ01000011_gene736	1.588e-43	168.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DH9I@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_1009162_0	1173020.Cha6605_2878	3.947e-173	556.0	COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria	1117|Cyanobacteria	E	Beta-eliminating lyase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158347_k127_1009162_1	1415780.JPOG01000001_gene2970	1.005e-143	473.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPJY@1236|Gammaproteobacteria,1X4PP@135614|Xanthomonadales	135614|Xanthomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
SRR25158347_k127_1009162_2	1089544.KB912942_gene6062	6.084e-89	302.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,4DZAC@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1009162_4	1121949.AQXT01000002_gene385	1.653e-05	53.0	2DNW5@1|root,32ZGI@2|Bacteria,1MZA8@1224|Proteobacteria,2UD5I@28211|Alphaproteobacteria,43YNX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
SRR25158347_k127_1009162_3	1223543.GP2_043_00300	5.32e-22	101.0	COG5592@1|root,COG5592@2|Bacteria,2IGW0@201174|Actinobacteria,4GDIF@85026|Gordoniaceae	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158347_k127_1011998_0	525909.Afer_1020	0.0	1533.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_1011998_10	1304275.C41B8_18191	6.406e-41	171.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	dmsD	GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
SRR25158347_k127_1011998_1	1313172.YM304_39870	9.548e-141	466.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4CMVK@84992|Acidimicrobiia	84992|Acidimicrobiia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158347_k127_1011998_13	406124.ACPC01000020_gene3777	1.57e-16	91.0	COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli,1ZI1V@1386|Bacillus	91061|Bacilli	O	Belongs to the sulfur carrier protein TusA family	yrkI	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	-	-	-	-	-	-	-	-	-	TusA
SRR25158347_k127_1011998_8	1429046.RR21198_5341	1.963e-55	198.0	COG2210@1|root,COG2210@2|Bacteria,2HGHZ@201174|Actinobacteria,4FXJI@85025|Nocardiaceae	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158347_k127_1011998_12	882083.SacmaDRAFT_2578	9.646e-29	129.0	COG0640@1|root,COG0640@2|Bacteria,2IKPW@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158347_k127_1011998_11	298655.KI912267_gene7582	2.343e-33	132.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,4EWT6@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158347_k127_1011998_3	911045.PSE_4973	1.885e-119	391.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_1011998_2	1463881.KL591035_gene4926	8.494e-134	436.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158347_k127_1011998_7	1380390.JIAT01000009_gene637	4.366e-63	239.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4CTX9@84995|Rubrobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158347_k127_1011998_9	1121920.AUAU01000018_gene1786	1.826e-54	202.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR25158347_k127_1011998_4	1122611.KB903969_gene2390	9.539e-106	359.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EN4W@85012|Streptosporangiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	tgs1	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158347_k127_1011998_6	525904.Tter_2551	2.917e-78	275.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
SRR25158347_k127_1011998_5	2074.JNYD01000026_gene644	1.44e-97	327.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E08C@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158347_k127_1023411_3	1172179.AUKV01000031_gene5171	2.372e-22	107.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1023411_0	710111.FraQA3DRAFT_4752	6.305e-131	427.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4ERRB@85013|Frankiales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	vdh	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.23	ko:K00271	ko00280,ko01100,ko01110,ko01130,map00280,map01100,map01110,map01130	-	R01212,R01434	RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158347_k127_1023411_1	390989.JOEG01000017_gene6259	1.495e-117	391.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4DASB@85008|Micromonosporales	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158347_k127_1023411_2	754252.PFREUD_04770	1.143e-22	99.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DN2S@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158347_k127_106737_34	1121377.KB906418_gene3787	4.18e-17	85.0	COG5640@1|root,COG5640@2|Bacteria,1WN2M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158347_k127_106737_10	497964.CfE428DRAFT_0631	3.003e-134	460.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158347_k127_106737_2	861299.J421_1936	8.562e-234	739.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158347_k127_106737_18	1172186.KB911465_gene4327	3.088e-66	235.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,234PI@1762|Mycobacteriaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_106737_9	251221.35212956	8.356e-136	460.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1G45B@1117|Cyanobacteria	1117|Cyanobacteria	PT	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158347_k127_106737_24	247634.GPB2148_3766	2.353e-48	188.0	COG5361@1|root,COG5361@2|Bacteria,1N5FS@1224|Proteobacteria,1SC45@1236|Gammaproteobacteria,1JBXV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
SRR25158347_k127_106737_15	335543.Sfum_3525	2.772e-88	306.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,42Z3E@68525|delta/epsilon subdivisions,2WU93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158347_k127_106737_6	1415754.JQMK01000012_gene1199	2.699e-158	510.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,464C9@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	cysD	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_1303	PAPS_reduct
SRR25158347_k127_106737_1	314230.DSM3645_09257	1.726e-244	774.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2IX1D@203682|Planctomycetes	203682|Planctomycetes	H	May be the GTPase, regulating ATP sulfurylase activity	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158347_k127_106737_3	196162.Noca_4403	1.128e-217	706.0	COG2355@1|root,COG2355@2|Bacteria,2HZ6F@201174|Actinobacteria,4DPCY@85009|Propionibacteriales	201174|Actinobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_106737_37	29540.C481_00045	1.504e-06	60.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SRR25158347_k127_106737_31	1112216.JH594425_gene1764	2.692e-27	128.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2U4EG@28211|Alphaproteobacteria,2K2HU@204457|Sphingomonadales	204457|Sphingomonadales	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS,PAS_9,Response_reg
SRR25158347_k127_106737_0	269800.Tfu_2239	2.622e-246	777.0	COG1960@1|root,COG1960@2|Bacteria,2GJ4X@201174|Actinobacteria,4EKCQ@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA oxidase	acx	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_106737_17	287986.DV20_34300	2.722e-78	271.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4DZV4@85010|Pseudonocardiales	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_106737_8	44060.JODL01000002_gene2165	6.491e-145	475.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_106737_4	675635.Psed_6174	1.739e-196	630.0	COG0183@1|root,COG0183@2|Bacteria,2GJI8@201174|Actinobacteria,4DXSK@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_106737_36	1380390.JIAT01000011_gene2858	8.141e-09	69.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Fer4_7,HTH_Crp_2,cNMP_binding
SRR25158347_k127_106737_25	28444.JODQ01000008_gene1181	1.403e-37	159.0	COG0664@1|root,COG0664@2|Bacteria,2I8QQ@201174|Actinobacteria,4EGBT@85012|Streptosporangiales	201174|Actinobacteria	T	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_106737_12	909613.UO65_5818	7.671e-114	381.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4DX45@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158347_k127_106737_27	525909.Afer_0695	4.068e-32	139.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4CNCN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158347_k127_106737_28	1120936.KB907215_gene3993	2.239e-31	131.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4EFNK@85012|Streptosporangiales	201174|Actinobacteria	K	transcriptional regulator	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158347_k127_106737_32	321332.CYB_0249	8.84e-25	108.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1GZ8T@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_106737_19	543632.JOJL01000005_gene4760	6.258e-66	249.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRR25158347_k127_106737_16	929712.KI912613_gene2927	1.17e-87	300.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CPI2@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158347_k127_106737_20	570268.ANBB01000019_gene4394	2.905e-58	226.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4EN5V@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158347_k127_106737_21	263358.VAB18032_25110	1.658e-55	210.0	COG0738@1|root,COG0738@2|Bacteria,2I4C7@201174|Actinobacteria,4DMQ0@85008|Micromonosporales	201174|Actinobacteria	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158347_k127_106737_29	1299327.I546_5781	8.451e-30	125.0	COG5485@1|root,COG5485@2|Bacteria,2INMM@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158347_k127_106737_23	1116232.AHBF01000058_gene521	2.247e-48	194.0	COG1670@1|root,COG1670@2|Bacteria,2IFNY@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferases including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158347_k127_106737_26	646529.Desaci_3974	3.21e-32	144.0	COG2247@1|root,COG5492@1|root,COG2247@2|Bacteria,COG5492@2|Bacteria,1TPEQ@1239|Firmicutes,24DNM@186801|Clostridia,2614X@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_2
SRR25158347_k127_106737_30	465515.Mlut_14360	3.94e-28	131.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,1W98D@1268|Micrococcaceae	201174|Actinobacteria	S	Transglycosylase-like domain	-	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
SRR25158347_k127_106737_38	269800.Tfu_0507	1.762e-05	55.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4EFVQ@85012|Streptosporangiales	201174|Actinobacteria	O	Trypsin-like peptidase domain	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_106737_5	227882.SAV_1345	2.2e-195	627.0	2CB1C@1|root,2Z7M2@2|Bacteria,2GM87@201174|Actinobacteria	201174|Actinobacteria	S	Transmembrane protein of unknown function (DUF3556)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3556
SRR25158347_k127_106737_33	345341.KUTG_03845	3.748e-24	110.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria,4E5WD@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_106737_11	483219.LILAB_28075	2.512e-114	386.0	COG0488@1|root,COG0488@2|Bacteria,1QUVR@1224|Proteobacteria,42P66@68525|delta/epsilon subdivisions,2WJ2D@28221|Deltaproteobacteria,2YWET@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158347_k127_106737_14	1229780.BN381_10294	7.921e-93	320.0	COG2733@1|root,COG2733@2|Bacteria,2GKGM@201174|Actinobacteria,3UX18@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158347_k127_106737_35	314230.DSM3645_06144	1.968e-12	82.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158347_k127_106737_13	1068980.ARVW01000001_gene3331	9.942e-112	409.0	COG5276@1|root,COG5276@2|Bacteria,2IAAZ@201174|Actinobacteria	201174|Actinobacteria	O	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,P_proprotein
SRR25158347_k127_106737_7	555079.Toce_2001	4.982e-157	507.0	COG2403@1|root,COG2403@2|Bacteria,1TPZD@1239|Firmicutes,24E2D@186801|Clostridia,42HSE@68295|Thermoanaerobacterales	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158347_k127_106737_22	263358.VAB18032_26626	8.963e-51	186.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4DB3G@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_1101583_4	634497.HAH_2435	4.199e-06	50.0	COG0596@1|root,arCOG01648@2157|Archaea	2157|Archaea	IQ	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
SRR25158347_k127_1101583_0	335543.Sfum_2279	6.823e-116	401.0	COG1404@1|root,COG1404@2|Bacteria,1PFBD@1224|Proteobacteria,43A1G@68525|delta/epsilon subdivisions,2X9U2@28221|Deltaproteobacteria,2MSGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158347_k127_1101583_3	309798.COPRO5265_0441	5.33e-16	93.0	COG1404@1|root,COG3292@1|root,COG5295@1|root,COG1404@2|Bacteria,COG3292@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	3.2.1.99,4.2.2.20,4.2.2.21	ko:K06113,ko:K08961,ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Cu_amine_oxidN1,Peptidase_S8,SLH,VCBS
SRR25158347_k127_1101583_1	158190.SpiGrapes_0053	2.362e-37	151.0	2EHEG@1|root,33B6E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158347_k127_1101583_2	1177594.MIC448_2190012	3.791e-19	99.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1104750_15	365528.KB891102_gene4586	1.777e-44	163.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4ESUM@85013|Frankiales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158347_k127_1104750_8	222534.KB893671_gene3130	2.918e-110	373.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4ERQF@85013|Frankiales	201174|Actinobacteria	H	Mur ligase, middle domain protein	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_1104750_17	868595.Desca_0706	3.469e-32	131.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25ZZS@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158347_k127_1104750_2	656024.FsymDg_1524	1.032e-178	566.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4ES3S@85013|Frankiales	201174|Actinobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158347_k127_1104750_13	1298880.AUEV01000003_gene3537	2.632e-50	191.0	COG1792@1|root,COG1792@2|Bacteria,2GJN0@201174|Actinobacteria	201174|Actinobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158347_k127_1104750_20	1223523.H340_24445	1.825e-10	68.0	COG2891@1|root,COG2891@2|Bacteria,2GN0I@201174|Actinobacteria	201174|Actinobacteria	M	rod shape-determining protein (MreD)	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158347_k127_1104750_5	469371.Tbis_1685	1.041e-136	462.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4E550@85010|Pseudonocardiales	201174|Actinobacteria	DM	PFAM penicillin-binding protein transpeptidase	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
SRR25158347_k127_1104750_11	561175.KB894104_gene1145	2.253e-86	306.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4EFT6@85012|Streptosporangiales	201174|Actinobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158347_k127_1104750_0	1120954.ATXE01000003_gene664	3.401e-244	773.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4DNWJ@85009|Propionibacteriales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158347_k127_1104750_16	457425.XNR_4342	3.905e-38	156.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158347_k127_1104750_6	1380354.JIAN01000006_gene1053	7.784e-131	440.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4F0RJ@85016|Cellulomonadaceae	201174|Actinobacteria	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158347_k127_1104750_3	471852.Tcur_2881	1.07e-171	559.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EG83@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_1104750_1	561175.KB894098_gene5360	4.683e-191	622.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EGNQ@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_1104750_4	1382306.JNIM01000001_gene2717	9.339e-169	549.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158347_k127_1104750_14	196162.Noca_4380	2.615e-47	183.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4DRCX@85009|Propionibacteriales	201174|Actinobacteria	O	PFAM Sucraseferredoxin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158347_k127_1104750_19	877420.ATVW01000001_gene2020	2.93e-23	103.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,27NZI@186928|unclassified Lachnospiraceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158347_k127_1104750_18	1224163.B841_10045	5.428e-31	123.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,22NIK@1653|Corynebacteriaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158347_k127_1104750_7	28444.JODQ01000007_gene6068	3.024e-124	413.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4EG53@85012|Streptosporangiales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158347_k127_1104750_9	471853.Bcav_1625	8.357e-102	344.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158347_k127_1104750_12	1304875.JAFZ01000001_gene1827	2.961e-54	196.0	COG1704@1|root,COG1704@2|Bacteria,3TAYK@508458|Synergistetes	508458|Synergistetes	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158347_k127_1104750_10	1306174.JODP01000032_gene4027	2.261e-95	338.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158347_k127_1108740_4	467200.ACFA01000087_gene1343	6.457e-31	123.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158347_k127_1108740_6	583355.Caka_1851	2.807e-14	78.0	COG0236@1|root,COG0236@2|Bacteria,46W39@74201|Verrucomicrobia,3K88G@414999|Opitutae	414999|Opitutae	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR25158347_k127_1108740_5	29306.JOBE01000003_gene4292	2.978e-17	91.0	COG2091@1|root,COG2091@2|Bacteria,2IQ65@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
SRR25158347_k127_1108740_1	1380347.JNII01000006_gene1150	8.838e-115	390.0	COG2986@1|root,COG2986@2|Bacteria,2GK17@201174|Actinobacteria,4EX88@85013|Frankiales	201174|Actinobacteria	E	Aromatic amino acid lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158347_k127_1108740_3	1157708.KB907454_gene2897	6.986e-39	149.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2VSXM@28216|Betaproteobacteria,4AENZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158347_k127_1108740_0	1122939.ATUD01000003_gene3524	0.0	1069.0	COG2838@1|root,COG2838@2|Bacteria,2GJ1C@201174|Actinobacteria,4CPDI@84995|Rubrobacteria	84995|Rubrobacteria	C	Monomeric isocitrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	IDH
SRR25158347_k127_1108740_2	1278078.G419_08399	1.694e-95	324.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4FVCA@85025|Nocardiaceae	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158347_k127_1108740_7	1121952.ATXT01000013_gene2421	0.0001004	54.0	COG1131@1|root,COG1131@2|Bacteria,2ICIF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_1110432_1	1206730.BAGA01000079_gene1262	1.566e-75	270.0	COG2220@1|root,COG2220@2|Bacteria,2IT2Z@201174|Actinobacteria,4FXF0@85025|Nocardiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_3
SRR25158347_k127_1110432_2	1289387.AUKW01000002_gene71	3.958e-50	186.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1110432_0	1122611.KB903939_gene373	9.288e-120	416.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4EH5T@85012|Streptosporangiales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158347_k127_1110432_3	1449048.JQKU01000022_gene2716	1.992e-43	172.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,23D4Q@1762|Mycobacteriaceae	201174|Actinobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158347_k127_1119410_5	1122604.JONR01000050_gene3146	1.106e-104	351.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1S01V@1236|Gammaproteobacteria,1X4DC@135614|Xanthomonadales	135614|Xanthomonadales	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158347_k127_1119410_2	287986.DV20_02610	1.104e-162	520.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	desA3_2	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158347_k127_1119410_13	1179773.BN6_00090	5.574e-11	72.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4E3F4@85010|Pseudonocardiales	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR25158347_k127_1119410_0	1408422.JHYF01000006_gene1011	3.986e-288	910.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158347_k127_1119410_1	269800.Tfu_0006	7.977e-252	793.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4EGRF@85012|Streptosporangiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158347_k127_1119410_4	204669.Acid345_0985	8.936e-115	378.0	COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria,2JKGK@204432|Acidobacteriia	204432|Acidobacteriia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158347_k127_1119410_12	414996.IL38_01650	2.82e-13	76.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4097V@622450|Actinopolysporales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158347_k127_1119410_6	710687.KI912270_gene5201	4.794e-97	331.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,233RS@1762|Mycobacteriaceae	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158347_k127_1119410_7	1123320.KB889730_gene6006	1.778e-81	285.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158347_k127_1119410_3	222534.KB893717_gene2024	1.104e-158	516.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4ES24@85013|Frankiales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158347_k127_1119410_11	398513.BBNG_01778	9.39e-14	73.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4D1EF@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158347_k127_1119410_14	1123360.thalar_02562	0.0001428	53.0	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158347_k127_1119410_10	1137268.AZXF01000017_gene2928	1.385e-19	93.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4EKGC@85012|Streptosporangiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158347_k127_1119410_8	1121385.AQXW01000004_gene2683	3.211e-39	158.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,1ZVSD@145357|Dermacoccaceae	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158347_k127_1119410_9	1463821.JOGR01000011_gene2086	2.489e-30	130.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4EYH2@85014|Glycomycetales	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158347_k127_1122291_4	926550.CLDAP_31690	1.035e-16	86.0	COG1028@1|root,COG1028@2|Bacteria,2G8KA@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1122291_5	1408473.JHXO01000015_gene1906	1.255e-16	94.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
SRR25158347_k127_1122291_2	1048339.KB913029_gene4038	3.911e-75	281.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_1122291_0	1229780.BN381_10243	2.331e-179	600.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_1122291_1	867845.KI911784_gene77	1.179e-92	316.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,376UU@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_1122291_3	313589.JNB_00590	2.153e-25	120.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4FFZY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158347_k127_1122291_6	452652.KSE_21350	5.803e-15	90.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,2M0H5@2063|Kitasatospora	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158347_k127_1127122_9	1385519.N801_03370	0.0007783	46.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4FIRP@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR25158347_k127_1127122_0	177437.HRM2_06570	1.276e-185	627.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,42XEE@68525|delta/epsilon subdivisions,2WT63@28221|Deltaproteobacteria,2MP6A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT
SRR25158347_k127_1127122_6	1183438.GKIL_2200	2.69e-21	98.0	2EEYW@1|root,32WKX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1127122_3	717785.HYPMC_3346	4.845e-51	203.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1R5X9@1224|Proteobacteria,2U15Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
SRR25158347_k127_1127122_8	1054213.HMPREF9946_01709	3.031e-13	81.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,2JTCZ@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_1127122_2	479433.Caci_7062	8.632e-62	224.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158347_k127_1127122_5	1380390.JIAT01000009_gene673	4.395e-24	111.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	yeaK	GO:0002161,GO:0002196,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006417,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0045727,GO:0045903,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:2000112	6.1.1.23	ko:K09759,ko:K19055	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HDOD,tRNA_edit
SRR25158347_k127_1127122_1	1120936.KB907211_gene83	5.313e-140	454.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4EIB7@85012|Streptosporangiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	lldA	-	1.13.12.4	ko:K00467	ko00620,map00620	-	R00319	RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158347_k127_1127122_7	1206735.BAGG01000252_gene6115	4.603e-18	93.0	2BJ1M@1|root,32DA7@2|Bacteria,2HJSJ@201174|Actinobacteria,4G7AD@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1127122_4	1380390.JIAT01000009_gene571	8.328e-46	175.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4CRRD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158347_k127_1144122_30	1075090.GOAMR_61_01690	3.176e-33	144.0	COG2936@1|root,COG2936@2|Bacteria,2IAA6@201174|Actinobacteria,4GA2U@85026|Gordoniaceae	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158347_k127_1144122_46	1122138.AQUZ01000058_gene3468	0.000159	53.0	2BJMZ@1|root,32DZH@2|Bacteria,2I1FG@201174|Actinobacteria,4DSHC@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158347_k127_1144122_39	706439.HMPREF9057_00100	2.731e-14	87.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4D4DN@85005|Actinomycetales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158347_k127_1144122_33	1283283.ATXA01000004_gene4479	1.871e-27	130.0	COG2064@1|root,COG2064@2|Bacteria,2GKMW@201174|Actinobacteria,4ESFS@85013|Frankiales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158347_k127_1144122_20	590998.Celf_2623	7.188e-62	231.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4F10A@85016|Cellulomonadaceae	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158347_k127_1144122_38	1095767.CAHD01000170_gene2529	7.15e-17	94.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4F1X2@85016|Cellulomonadaceae	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158347_k127_1144122_43	1206739.BAGJ01000155_gene3515	4.506e-07	60.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,4G9B7@85025|Nocardiaceae	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
SRR25158347_k127_1144122_47	471870.BACINT_04579	0.0008324	47.0	2A371@1|root,30RNK@2|Bacteria,4PDX5@976|Bacteroidetes,2FRCD@200643|Bacteroidia,4AP3M@815|Bacteroidaceae	976|Bacteroidetes	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158347_k127_1144122_40	1283299.AUKG01000003_gene576	9.729e-13	78.0	2DPU0@1|root,333DA@2|Bacteria,2HPPH@201174|Actinobacteria,4CR26@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1144122_9	1313172.YM304_26920	4.439e-141	484.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,2GISS@201174|Actinobacteria,4CMS6@84992|Acidimicrobiia	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158347_k127_1144122_36	1068980.ARVW01000001_gene5010	1.245e-23	113.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158347_k127_1144122_4	1229780.BN381_180020	4.26e-168	545.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,3UW9B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
SRR25158347_k127_1144122_41	1386969.AWTB01000007_gene2713	2.222e-12	78.0	COG3427@1|root,COG3427@2|Bacteria,2GW22@201174|Actinobacteria,4GE9J@85026|Gordoniaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_1144122_7	1048339.KB913029_gene2844	4.687e-151	489.0	COG1363@1|root,COG1363@2|Bacteria,2HNDC@201174|Actinobacteria,4EWQK@85013|Frankiales	201174|Actinobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158347_k127_1144122_37	1449048.JQKU01000018_gene4280	6.987e-18	94.0	COG2852@1|root,COG2852@2|Bacteria,2GSDS@201174|Actinobacteria,232PY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158347_k127_1144122_1	710687.KI912270_gene1777	1.626e-229	725.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,2GN0U@201174|Actinobacteria,2356T@1762|Mycobacteriaceae	201174|Actinobacteria	HJK	acetyltransferase	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158347_k127_1144122_0	547163.BN979_03272	1.638e-271	846.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,232RF@1762|Mycobacteriaceae	201174|Actinobacteria	E	Asparagine synthase	asnB_1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_1144122_22	593907.Celgi_1447	3.259e-54	208.0	COG0454@1|root,COG0456@2|Bacteria,2I0BQ@201174|Actinobacteria,4F17M@85016|Cellulomonadaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_1144122_15	43354.JOIJ01000002_gene4184	3.903e-107	354.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4DYKR@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_1144122_16	1120950.KB892731_gene3871	6.555e-92	329.0	COG2936@1|root,COG2936@2|Bacteria,2I357@201174|Actinobacteria,4DSBH@85009|Propionibacteriales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	PepX_C,Peptidase_S15
SRR25158347_k127_1144122_19	765913.ThidrDRAFT_0498	2.3e-64	237.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,1RRKZ@1236|Gammaproteobacteria,1WWQA@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158347_k127_1144122_31	1120950.KB892707_gene4817	3.428e-33	141.0	COG2334@1|root,COG2867@1|root,COG2334@2|Bacteria,COG2867@2|Bacteria,2IIBS@201174|Actinobacteria	201174|Actinobacteria	I	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1144122_34	1121468.AUBR01000014_gene2220	6.201e-26	126.0	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,24BWJ@186801|Clostridia,42FA5@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Dynamin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158347_k127_1144122_8	512565.AMIS_32830	5.902e-147	494.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DBTV@85008|Micromonosporales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_1144122_5	1048339.KB913029_gene1969	6.216e-153	518.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_1144122_10	1048339.KB913029_gene4038	2.854e-126	434.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_1144122_6	29306.JOBE01000083_gene5538	1.034e-151	490.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRR25158347_k127_1144122_28	1476583.DEIPH_ctg033orf0060	2.393e-35	146.0	COG0490@1|root,COG0490@2|Bacteria	2|Bacteria	P	domain, Protein	khtT	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158347_k127_1144122_13	67352.JODS01000036_gene6904	5.889e-112	376.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158347_k127_1144122_24	1307759.JOMJ01000003_gene1217	8.587e-42	175.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Y5I@68525|delta/epsilon subdivisions,2WUGI@28221|Deltaproteobacteria,2MEJ5@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_1144122_29	1211815.CBYP010000056_gene3336	2.466e-33	142.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4ESRE@85013|Frankiales	201174|Actinobacteria	T	FHA domain containing protein	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158347_k127_1144122_35	469371.Tbis_0050	8.867e-24	109.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4E2PP@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158347_k127_1144122_18	266940.Krad_0075	6.404e-68	252.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria	201174|Actinobacteria	T	Phosphatase	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158347_k127_1144122_12	2074.JNYD01000004_gene4916	1.021e-119	401.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DZX9@85010|Pseudonocardiales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158347_k127_1144122_14	1120950.KB892743_gene3151	1.559e-110	378.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4DP0A@85009|Propionibacteriales	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158347_k127_1144122_45	1229780.BN381_130338	6.4e-05	54.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158347_k127_1144122_3	479433.Caci_7971	2.218e-179	569.0	COG4992@1|root,COG4992@2|Bacteria,2GK0J@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_1144122_27	40571.JOEA01000030_gene5596	1.255e-40	155.0	COG0454@1|root,COG0456@2|Bacteria,2IJC7@201174|Actinobacteria,4E5XB@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_1144122_11	351607.Acel_0019	4.166e-120	407.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158347_k127_1144122_32	1122622.ATWJ01000013_gene208	3.025e-31	129.0	COG0599@1|root,COG0599@2|Bacteria,2IRPW@201174|Actinobacteria,4FJCM@85021|Intrasporangiaceae	201174|Actinobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158347_k127_1144122_42	525909.Afer_1115	2.412e-07	59.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1144122_26	1313172.YM304_37010	9.152e-41	166.0	2DE9Z@1|root,32U2Z@2|Bacteria,2ID6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1144122_44	28583.AMAG_17153T0	2.732e-06	59.0	2CYXB@1|root,2S70Z@2759|Eukaryota,3A94M@33154|Opisthokonta,3P7N6@4751|Fungi	4751|Fungi	S	Domain of unkown function (DUF1775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1775
SRR25158347_k127_1144122_21	1146883.BLASA_0706	3.895e-57	222.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4ESVK@85013|Frankiales	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158347_k127_1144122_2	1449353.JQMQ01000005_gene5516	1.304e-182	580.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,2NGFF@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158347_k127_1144122_25	1298863.AUEP01000013_gene4049	6.778e-41	168.0	COG0642@1|root,COG2205@2|Bacteria	1298863.AUEP01000013_gene4049|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1144122_23	1121946.AUAX01000003_gene1447	2.162e-50	190.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria,4DIAN@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158347_k127_1144122_17	1122611.KB903944_gene1166	1.105e-81	280.0	COG0215@1|root,COG0215@2|Bacteria,2I98G@201174|Actinobacteria,4EIE4@85012|Streptosporangiales	201174|Actinobacteria	J	cysteine-tRNA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1152335_22	1380393.JHVP01000002_gene1764	3.063e-55	201.0	COG1816@1|root,COG1816@2|Bacteria,2H2G6@201174|Actinobacteria,4EX6S@85013|Frankiales	201174|Actinobacteria	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158347_k127_1152335_2	298655.KI912266_gene1062	4.542e-213	669.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4ESB0@85013|Frankiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158347_k127_1152335_33	656024.FsymDg_0858	1.417e-30	134.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4ET44@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158347_k127_1152335_23	1313172.YM304_34380	3.259e-54	200.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria	201174|Actinobacteria	L	Glycosylase	nei	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158347_k127_1152335_1	1122138.AQUZ01000010_gene5101	0.0	1482.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4DPDX@85009|Propionibacteriales	201174|Actinobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158347_k127_1152335_7	994479.GL877881_gene6465	1.803e-131	451.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4DZI6@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158347_k127_1152335_41	1121946.AUAX01000031_gene1020	4.429e-18	89.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_1152335_13	1123519.PSJM300_09945	4.1e-85	289.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1Z274@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fadB2x	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158347_k127_1152335_34	1449068.JMLQ01000005_gene3604	1.068e-29	133.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4FTVW@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158347_k127_1152335_18	1313172.YM304_31180	2.202e-61	220.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K11603	ko02010,ko02020,map02010,map02020	M00316	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.1	-	-	ABC_tran
SRR25158347_k127_1152335_26	1404245.CGLY_01880	1.366e-51	194.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,22RDP@1653|Corynebacteriaceae	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	mntC	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158347_k127_1152335_14	1045009.AFXQ01000011_gene474	7.65e-74	258.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,1W8TI@1268|Micrococcaceae	201174|Actinobacteria	P	ABC 3 transport family	mntB	-	-	ko:K02075,ko:K09819	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158347_k127_1152335_31	1313172.YM304_21830	4.949e-31	127.0	COG0735@1|root,COG0735@2|Bacteria,2HGFN@201174|Actinobacteria,4CND6@84992|Acidimicrobiia	84992|Acidimicrobiia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158347_k127_1152335_43	345341.KUTG_08611	7.853e-14	85.0	COG1520@1|root,COG2385@1|root,COG1520@2|Bacteria,COG2385@2|Bacteria,2I3H6@201174|Actinobacteria,4EE3C@85010|Pseudonocardiales	201174|Actinobacteria	D	Tachylectin	-	-	-	-	-	-	-	-	-	-	-	-	Tachylectin
SRR25158347_k127_1152335_9	1283299.AUKG01000001_gene3127	3.282e-124	415.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CPIV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158347_k127_1152335_25	644548.SCNU_15909	6.064e-53	190.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4GDT5@85026|Gordoniaceae	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158347_k127_1152335_10	1157637.KB892097_gene1220	2.925e-118	399.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria	201174|Actinobacteria	F	Pfam Amidohydrolase	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158347_k127_1152335_37	1313172.YM304_39100	1.15e-24	105.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158347_k127_1152335_28	1229780.BN381_350010	1.686e-39	151.0	COG1487@1|root,COG1487@2|Bacteria,2IGMY@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_1152335_15	1380390.JIAT01000010_gene3850	1.284e-73	263.0	COG2114@1|root,COG2114@2|Bacteria,2HSA4@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	cya	GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158347_k127_1152335_21	479431.Namu_3002	4.528e-58	208.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4ET32@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1152335_50	103733.JNYO01000022_gene6986	0.0002844	47.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria,4E30Q@85010|Pseudonocardiales	201174|Actinobacteria	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675,ko:K15466	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001,ko01000,ko01008	-	-	-	Acetyltransf_2
SRR25158347_k127_1152335_36	58123.JOFJ01000018_gene4338	6.663e-27	118.0	COG1695@1|root,COG1695@2|Bacteria,2H1J3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158347_k127_1152335_51	159450.NH14_14465	0.0003129	47.0	COG3093@1|root,COG3093@2|Bacteria,1PSXX@1224|Proteobacteria,2WAF2@28216|Betaproteobacteria,1K9WE@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158347_k127_1152335_42	234621.RER_19490	3.316e-14	75.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FZ9I@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR25158347_k127_1152335_5	1121939.L861_17285	6.085e-155	503.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158347_k127_1152335_35	525909.Afer_1166	1.558e-28	118.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	relF	GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
SRR25158347_k127_1152335_40	525909.Afer_1167	4.003e-18	87.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158347_k127_1152335_30	298654.FraEuI1c_5095	5.962e-33	134.0	COG1848@1|root,COG1848@2|Bacteria,2IQB5@201174|Actinobacteria,4EWC0@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158347_k127_1152335_38	298655.KI912266_gene5583	3.779e-21	95.0	COG4118@1|root,COG4118@2|Bacteria,2GQNI@201174|Actinobacteria,4EW86@85013|Frankiales	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158347_k127_1152335_27	1449044.JMLE01000038_gene347	8.199e-40	162.0	2DM8J@1|root,32695@2|Bacteria,2I7RY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1152335_17	1304865.JAGF01000001_gene22	8.258e-70	247.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158347_k127_1152335_32	446468.Ndas_4463	6.357e-31	130.0	COG1309@1|root,COG1309@2|Bacteria,2HG87@201174|Actinobacteria,4EJDX@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_1152335_11	44060.JODL01000002_gene2338	1.61e-102	349.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_1152335_16	1348663.KCH_18540	4.868e-71	251.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,2M05I@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158347_k127_1152335_24	1449063.JMLS01000019_gene5655	1.475e-53	211.0	COG1305@1|root,COG1305@2|Bacteria,1V4HE@1239|Firmicutes,4HF4E@91061|Bacilli,26UF4@186822|Paenibacillaceae	91061|Bacilli	E	transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158347_k127_1152335_20	1120965.AUBV01000001_gene3550	4.378e-58	214.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,47JTD@768503|Cytophagia	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRR25158347_k127_1152335_4	234267.Acid_2499	9.752e-173	563.0	COG2308@1|root,COG2308@2|Bacteria,3Y2FR@57723|Acidobacteria	57723|Acidobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158347_k127_1152335_49	42256.RradSPS_1549	4.859e-05	54.0	29DTG@1|root,300RC@2|Bacteria,2HCYB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1152335_6	1121920.AUAU01000004_gene886	2.249e-148	482.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria	57723|Acidobacteria	E	Cys Met metabolism	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
SRR25158347_k127_1152335_45	1121405.dsmv_0046	5.03e-11	70.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_1152335_12	595460.RRSWK_03756	1.763e-99	350.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158347_k127_1152335_0	1184607.AUCHE_05_04270	0.0	1536.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158347_k127_1152335_29	882083.SacmaDRAFT_4273	4.148e-36	152.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	-	2.7.13.3	ko:K02484,ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_8,Response_reg
SRR25158347_k127_1152335_44	543632.JOJL01000015_gene8687	1.046e-13	83.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4DDYY@85008|Micromonosporales	201174|Actinobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158347_k127_1152335_3	1479238.JQMZ01000001_gene234	4.398e-212	680.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2V9IG@28211|Alphaproteobacteria,43Z5S@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158347_k127_1152335_8	485913.Krac_2282	2.776e-127	424.0	COG0154@1|root,COG0154@2|Bacteria,2G6JQ@200795|Chloroflexi	200795|Chloroflexi	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158347_k127_1152335_19	1380347.JNII01000006_gene1588	6.985e-61	215.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4ESEE@85013|Frankiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158347_k127_1171458_14	1246995.AFR_05620	2.294e-106	353.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4D8NB@85008|Micromonosporales	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158347_k127_1171458_9	926550.CLDAP_24680	9.864e-162	533.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_1171458_11	561175.KB894093_gene3201	3.221e-137	455.0	COG1109@1|root,COG1109@2|Bacteria,2GJ3Q@201174|Actinobacteria,4EHG1@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pmmB	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158347_k127_1171458_21	28444.JODQ01000017_gene6543	3.146e-71	255.0	COG2380@1|root,COG2380@2|Bacteria,2I8F9@201174|Actinobacteria,4EI5H@85012|Streptosporangiales	201174|Actinobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1171458_12	356851.JOAN01000008_gene3002	8.477e-124	434.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DA3T@85008|Micromonosporales	201174|Actinobacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
SRR25158347_k127_1171458_15	28444.JODQ01000017_gene6541	8.3e-103	347.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4EG3S@85012|Streptosporangiales	201174|Actinobacteria	L	Calcineurin-like phosphoesterase superfamily domain	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
SRR25158347_k127_1171458_27	247633.GP2143_17911	1.812e-45	177.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_1171458_1	390989.JOEG01000012_gene3403	3.485e-233	735.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
SRR25158347_k127_1171458_22	640511.BC1002_1659	1.773e-69	251.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WHDJ@28216|Betaproteobacteria,1KIMS@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MEDS,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158347_k127_1171458_33	1144275.COCOR_07590	6.548e-21	105.0	COG3554@1|root,COG3554@2|Bacteria,1PV1V@1224|Proteobacteria,42XVB@68525|delta/epsilon subdivisions,2WXJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158347_k127_1171458_30	1192034.CAP_4592	7.238e-34	144.0	COG0454@1|root,COG0456@2|Bacteria,1RFZI@1224|Proteobacteria	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158347_k127_1171458_19	477641.MODMU_2075	1.869e-78	277.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4ESAR@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD, ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158347_k127_1171458_18	1009370.ALO_10424	1.151e-78	272.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4H2SP@909932|Negativicutes	909932|Negativicutes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158347_k127_1171458_16	452637.Oter_4308	1.906e-101	338.0	COG3285@1|root,COG3285@2|Bacteria,46S4K@74201|Verrucomicrobia	74201|Verrucomicrobia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158347_k127_1171458_20	292459.STH2009	1.037e-76	272.0	COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,248E0@186801|Clostridia	186801|Clostridia	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158347_k127_1171458_34	1211579.PP4_25470	8.964e-18	86.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	capB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158347_k127_1171458_4	521098.Aaci_0006	1.564e-205	665.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,2783E@186823|Alicyclobacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158347_k127_1171458_5	269800.Tfu_0006	2.353e-205	674.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4EGRF@85012|Streptosporangiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158347_k127_1171458_26	357808.RoseRS_3357	1.261e-47	183.0	COG0745@1|root,COG0745@2|Bacteria,2GBMQ@200795|Chloroflexi,377KX@32061|Chloroflexia	32061|Chloroflexia	KT	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_1171458_32	1454004.AW11_01694	4.976e-27	122.0	COG4251@1|root,COG4251@2|Bacteria,1N44A@1224|Proteobacteria	1224|Proteobacteria	T	PFAM KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
SRR25158347_k127_1171458_3	357808.RoseRS_3359	1.237e-205	657.0	COG0467@1|root,COG0467@2|Bacteria,2G8TX@200795|Chloroflexi,376XI@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Circadian clock protein KaiC central region	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158347_k127_1171458_25	28444.JODQ01000008_gene1080	8.402e-50	190.0	COG5002@1|root,COG5002@2|Bacteria,2I3C6@201174|Actinobacteria,4EMHB@85012|Streptosporangiales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158347_k127_1171458_23	1128421.JAGA01000004_gene2575	2.205e-57	208.0	COG1051@1|root,COG1051@2|Bacteria,2NPYB@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158347_k127_1171458_28	314271.RB2654_15776	2.971e-38	150.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	1.1.1.133,4.2.1.46,5.1.3.13	ko:K00067,ko:K01710,ko:K01790	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R02777,R06513,R06514	RC00182,RC00402,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158347_k127_1171458_2	710685.MycrhN_5167	1.603e-224	707.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,23802@1762|Mycobacteriaceae	201174|Actinobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158347_k127_1171458_7	1211815.CBYP010000063_gene1912	4.241e-170	576.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158347_k127_1171458_8	344747.PM8797T_11546	1.455e-162	542.0	COG0210@1|root,COG0210@2|Bacteria,2IY8S@203682|Planctomycetes	203682|Planctomycetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158347_k127_1171458_17	1380390.JIAT01000010_gene3951	2.835e-94	325.0	COG3287@1|root,COG3287@2|Bacteria,2GTCE@201174|Actinobacteria	201174|Actinobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158347_k127_1171458_29	635013.TherJR_1195	1.529e-34	147.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,260ZK@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158347_k127_1171458_0	1313172.YM304_35460	6.154e-297	928.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158347_k127_1171458_13	1122182.KB903834_gene5913	1.25e-109	369.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,4D8XK@85008|Micromonosporales	201174|Actinobacteria	S	peptidase U62, modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158347_k127_1171458_6	477641.MODMU_1128	1.091e-184	589.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4ERBS@85013|Frankiales	201174|Actinobacteria	S	peptidase U62, modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158347_k127_1171458_24	749414.SBI_04015	1.552e-50	193.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158347_k127_1171458_31	404589.Anae109_0321	3.19e-27	120.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,434T9@68525|delta/epsilon subdivisions,2WZ49@28221|Deltaproteobacteria,2Z1AM@29|Myxococcales	28221|Deltaproteobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
SRR25158347_k127_1171458_10	392499.Swit_1745	9.841e-146	477.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158347_k127_1171458_35	1146883.BLASA_0999	0.0005324	49.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD
SRR25158347_k127_1180443_1	1198114.AciX9_2007	1.44e-124	410.0	COG2826@1|root,COG2826@2|Bacteria,3Y896@57723|Acidobacteria,2JN59@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158347_k127_1180443_9	1463845.JOIG01000003_gene4897	1.538e-30	124.0	COG1487@1|root,COG1487@2|Bacteria,2ISD3@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_1180443_14	1463909.KL585973_gene87	2.895e-06	52.0	COG4118@1|root,COG4118@2|Bacteria,2GQXR@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158347_k127_1180443_8	266940.Krad_3106	1.784e-45	173.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158347_k127_1180443_6	477641.MODMU_0214	5.085e-67	239.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria,4ETHW@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158347_k127_1180443_5	1122138.AQUZ01000001_gene1541	3.01e-81	286.0	COG2321@1|root,COG2321@2|Bacteria,2H3UT@201174|Actinobacteria,4DQBN@85009|Propionibacteriales	201174|Actinobacteria	S	Putative neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158347_k127_1180443_10	134676.ACPL_3091	2.663e-29	134.0	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,2IBPU@201174|Actinobacteria,4DAU6@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_3,Guanylate_cyc,HATPase_c,HisKA,Pkinase
SRR25158347_k127_1180443_2	696747.NIES39_B01060	1.865e-111	376.0	COG1840@1|root,COG1840@2|Bacteria,1G0PQ@1117|Cyanobacteria,1H90N@1150|Oscillatoriales	1117|Cyanobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158347_k127_1180443_0	266117.Rxyl_1174	2.251e-158	518.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158347_k127_1180443_4	357808.RoseRS_0795	1.711e-102	344.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi,37556@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158347_k127_1180443_12	1246448.ANAZ01000024_gene2902	4.104e-22	102.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4EHWP@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix diphteria tox regulatory element	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158347_k127_1180443_11	1179773.BN6_83620	4.414e-27	114.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4E4DG@85010|Pseudonocardiales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158347_k127_1180443_3	1192034.CAP_7431	4.927e-106	350.0	COG0508@1|root,COG0508@2|Bacteria,1Q4SN@1224|Proteobacteria,437G3@68525|delta/epsilon subdivisions,2X2NP@28221|Deltaproteobacteria,2YU1R@29|Myxococcales	28221|Deltaproteobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR25158347_k127_1180443_7	1123377.AUIV01000001_gene875	4.254e-57	217.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1X3SR@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_1180443_13	1068980.ARVW01000001_gene110	3.152e-09	66.0	COG2267@1|root,COG2267@2|Bacteria,2GJNF@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_121326_2	1122622.ATWJ01000014_gene448	2.053e-101	335.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158347_k127_121326_0	351607.Acel_1545	1.945e-222	719.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158347_k127_121326_9	1265310.CCBD010000054_gene1487	1.929e-48	192.0	2E3JJ@1|root,32YHY@2|Bacteria,2I2W8@201174|Actinobacteria,237ZG@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_121326_21	1035193.HMPREF9073_01259	6.08e-05	53.0	2AIE8@1|root,318VP@2|Bacteria,4NQHF@976|Bacteroidetes,1I39Y@117743|Flavobacteriia,1ESAW@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_121326_11	743525.TSC_c23140	9.692e-45	168.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158347_k127_121326_3	710686.Mycsm_01630	1.511e-80	283.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,235VP@1762|Mycobacteriaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158347_k127_121326_6	179408.Osc7112_2645	7.75e-54	216.0	COG2211@1|root,COG2211@2|Bacteria,1G0JI@1117|Cyanobacteria,1H95J@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM PUCC protein	pucC	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
SRR25158347_k127_121326_15	1229780.BN381_10243	4.589e-35	155.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_121326_5	1048339.KB913029_gene1969	1.205e-67	262.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_121326_19	1048339.KB913029_gene1968	1.764e-08	67.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_121326_12	1177594.MIC448_2050030	1.157e-44	172.0	COG5398@1|root,COG5398@2|Bacteria,2H90I@201174|Actinobacteria,4FNDA@85023|Microbacteriaceae	201174|Actinobacteria	P	Heme oxygenase	hmuO	-	1.14.15.20	ko:K21480	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11579	RC01270	ko00000,ko00001,ko01000	-	-	-	Heme_oxygenase
SRR25158347_k127_121326_17	196162.Noca_4098	2.368e-17	91.0	2AE7Y@1|root,3141Y@2|Bacteria,2HDMT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_121326_16	103733.JNYO01000008_gene5625	1.8e-22	104.0	COG3787@1|root,COG3787@2|Bacteria,2H62A@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0306 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_121326_8	196162.Noca_4068	1.864e-48	190.0	COG0251@1|root,COG0251@2|Bacteria,2IB5I@201174|Actinobacteria	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158347_k127_121326_14	211114.JOEF01000031_gene1877	4.365e-38	150.0	COG1309@1|root,COG1309@2|Bacteria,2I0Y2@201174|Actinobacteria,4E2PJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_121326_20	1273125.Rrhod_1707	1.155e-06	57.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4G4CD@85025|Nocardiaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_121326_4	485913.Krac_2686	3.334e-78	271.0	KOG1110@1|root,2Z8YY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1838
SRR25158347_k127_121326_7	102129.Lepto7375DRAFT_2059	2e-50	184.0	28PWG@1|root,2ZCGU@2|Bacteria,1G5G3@1117|Cyanobacteria,1HBAZ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3598
SRR25158347_k127_121326_10	321327.CYA_0408	3.596e-46	175.0	COG5398@1|root,COG5398@2|Bacteria,1G07N@1117|Cyanobacteria,1GYEC@1129|Synechococcus	1117|Cyanobacteria	C	Heme oxygenase	ho1	GO:0003674,GO:0003824,GO:0004392,GO:0005488,GO:0005575,GO:0006725,GO:0006778,GO:0006787,GO:0006788,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016491,GO:0016705,GO:0019439,GO:0020037,GO:0033013,GO:0033015,GO:0034641,GO:0042167,GO:0042168,GO:0042440,GO:0042592,GO:0044237,GO:0044248,GO:0044270,GO:0046149,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051187,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:0098771,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575	1.14.15.20	ko:K21480	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11579	RC01270	ko00000,ko00001,ko01000	-	-	-	Heme_oxygenase
SRR25158347_k127_121326_1	196162.Noca_4065	5.628e-107	373.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_121326_13	547163.BN979_03714	2.97e-44	171.0	COG1024@1|root,COG1024@2|Bacteria,2HDCI@201174|Actinobacteria,233H5@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_121326_18	195250.CM001776_gene1130	1.577e-15	83.0	COG0388@1|root,COG0388@2|Bacteria,1G42J@1117|Cyanobacteria,1GZW8@1129|Synechococcus	1117|Cyanobacteria	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	amiF	-	3.5.1.4,3.5.1.49	ko:K01426,ko:K01455	ko00330,ko00360,ko00380,ko00460,ko00627,ko00630,ko00643,ko00910,ko01120,ko01200,map00330,map00360,map00380,map00460,map00627,map00630,map00643,map00910,map01120,map01200	-	R00524,R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025,RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158347_k127_1221403_5	1123023.JIAI01000029_gene4461	1.385e-94	319.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DZZG@85010|Pseudonocardiales	201174|Actinobacteria	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158347_k127_1221403_14	469371.Tbis_2055	3.298e-52	196.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4E019@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158347_k127_1221403_4	1394178.AWOO02000049_gene6162	8.476e-111	372.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria,4EHXG@85012|Streptosporangiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158347_k127_1221403_18	243230.DR_1148	2.633e-38	156.0	COG0490@1|root,COG0490@2|Bacteria,1WJS3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	regulatory, ligand-binding protein related to C-terminal domains of K channels	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158347_k127_1221403_23	272123.Anacy_0100	2.739e-07	63.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1G26E@1117|Cyanobacteria,1HM7G@1161|Nostocales	1117|Cyanobacteria	PT	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158347_k127_1221403_0	1120934.KB894436_gene4357	6.031e-256	810.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4E0NQ@85010|Pseudonocardiales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158347_k127_1221403_8	351607.Acel_1340	1.436e-70	251.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4ERCU@85013|Frankiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158347_k127_1221403_9	298655.KI912266_gene5208	7.017e-69	256.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4ERTD@85013|Frankiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158347_k127_1221403_10	264732.Moth_1692	1.452e-67	243.0	COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,42FRF@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158347_k127_1221403_22	935837.JAEK01000001_gene2102	3.279e-15	80.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,1ZHST@1386|Bacillus	91061|Bacilli	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158347_k127_1221403_3	43354.JOIJ01000002_gene4575	2.093e-137	446.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4DZHQ@85010|Pseudonocardiales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158347_k127_1221403_17	292459.STH1160	1.163e-38	160.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158347_k127_1221403_20	1229203.KI301992_gene974	1.714e-35	142.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,3UWKV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158347_k127_1221403_19	1449058.JQKT01000009_gene191	4.943e-38	158.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1221403_7	58123.JOFJ01000017_gene4170	2.273e-71	249.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4EGE0@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158347_k127_1221403_11	298655.KI912266_gene5214	2.757e-63	232.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4ESCW@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158347_k127_1221403_2	446470.Snas_2410	4.973e-151	486.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4EXKY@85014|Glycomycetales	201174|Actinobacteria	H	SOR/SNZ family	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158347_k127_1221403_15	446469.Sked_07280	4.31e-52	201.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158347_k127_1221403_12	650150.ERH_0111	6.855e-56	200.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,3VQJK@526524|Erysipelotrichia	526524|Erysipelotrichia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158347_k127_1221403_6	479432.Sros_6124	6.317e-73	260.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4EGYP@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158347_k127_1221403_16	164757.Mjls_2284	1.911e-43	172.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,2332N@1762|Mycobacteriaceae	201174|Actinobacteria	M	Acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158347_k127_1221403_21	1267535.KB906767_gene3789	3.942e-30	130.0	COG0558@1|root,COG0558@2|Bacteria,3Y427@57723|Acidobacteria,2JID7@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158347_k127_1221403_13	469371.Tbis_2077	6.871e-54	195.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4DYSQ@85010|Pseudonocardiales	201174|Actinobacteria	FG	HIT family hydrolase, diadenosine tetraphosphate hydrolase	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158347_k127_1221403_1	1313172.YM304_19720	7.317e-203	648.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CMTQ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158347_k127_1237514_10	861299.J421_2533	9.279e-37	150.0	COG2096@1|root,COG2096@2|Bacteria,1ZT4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158347_k127_1237514_7	1521187.JPIM01000025_gene1117	3.441e-56	211.0	COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi,375F3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
SRR25158347_k127_1237514_8	1123258.AQXZ01000012_gene1986	2.688e-52	196.0	COG2267@1|root,COG2267@2|Bacteria,2I2KD@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	ephA	GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_1237514_5	66429.JOFL01000002_gene4126	6.374e-98	330.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158347_k127_1237514_2	1122182.KB903839_gene973	6.576e-155	507.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4DBKE@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158347_k127_1237514_3	1158607.UAU_00625	2.379e-117	394.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,4B4TP@81852|Enterococcaceae	91061|Bacilli	P	Nitrogen regulatory protein P-II	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158347_k127_1237514_4	351627.Csac_2477	4.165e-115	383.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,42FEB@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
SRR25158347_k127_1237514_0	590998.Celf_2238	1.194e-194	616.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4F10R@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM glutamine synthetase catalytic region	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158347_k127_1237514_1	469371.Tbis_1261	4.279e-191	645.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4DZJZ@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158347_k127_1237514_9	251221.35214833	2.096e-37	152.0	COG0596@1|root,COG0596@2|Bacteria,1G2DE@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_1237514_11	1463934.JOCF01000103_gene7443	1.732e-28	124.0	COG0637@1|root,COG0637@2|Bacteria,2I990@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HAD_2
SRR25158347_k127_1237514_6	543632.JOJL01000050_gene7447	1.065e-86	304.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DH9I@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_1246002_3	58344.JOEL01000003_gene1363	2.822e-131	448.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158347_k127_1246002_7	926569.ANT_12740	3.192e-76	284.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158347_k127_1246002_9	526225.Gobs_4024	1.084e-48	184.0	COG3568@1|root,COG3568@2|Bacteria,2GNF9@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158347_k127_1246002_11	1313172.YM304_28820	2.475e-29	135.0	COG0741@1|root,COG0741@2|Bacteria,2IF18@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158347_k127_1246002_12	1237500.ANBA01000007_gene3009	3.128e-29	130.0	COG0124@1|root,COG0124@2|Bacteria,2GJXW@201174|Actinobacteria,4EJDF@85012|Streptosporangiales	201174|Actinobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1246002_4	67352.JODS01000002_gene1356	1.822e-119	404.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria	201174|Actinobacteria	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158347_k127_1246002_10	1385521.N803_09700	2.364e-39	160.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158347_k127_1246002_1	1128421.JAGA01000002_gene634	2.716e-140	473.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
SRR25158347_k127_1246002_0	1122611.KB903960_gene4326	7.088e-177	567.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4EHDH@85012|Streptosporangiales	201174|Actinobacteria	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158347_k127_1246002_6	469383.Cwoe_1310	1.902e-77	275.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4CSBE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_1246002_5	1123023.JIAI01000012_gene9125	9.226e-86	308.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4E020@85010|Pseudonocardiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158347_k127_1246002_8	1122138.AQUZ01000003_gene399	7.945e-60	228.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4DQNH@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158347_k127_1246002_2	1304865.JAGF01000001_gene3757	6.978e-136	440.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158347_k127_1246002_13	1298864.AUEQ01000006_gene5434	1.857e-08	63.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,233BV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158347_k127_1250850_3	880073.Calab_2291	8.084e-54	196.0	COG0264@1|root,COG0264@2|Bacteria,2NP3B@2323|unclassified Bacteria	2|Bacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158347_k127_1250850_1	685727.REQ_18190	1.117e-94	338.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4FTWY@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158347_k127_1250850_8	1064537.AGSO01000009_gene2233	4.272e-21	107.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4FD0R@85020|Dermabacteraceae	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_1250850_2	1996.JOFO01000047_gene2803	3.927e-86	292.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4EQ1Q@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_1250850_4	269799.Gmet_0890	1.632e-39	164.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158347_k127_1250850_0	33876.JNXY01000027_gene3602	7.694e-122	407.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4DB4N@85008|Micromonosporales	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158347_k127_1250850_7	1123258.AQXZ01000019_gene2706	1.182e-25	110.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4G1R8@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158347_k127_1250850_5	754252.PFREUD_14260	2.161e-37	143.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4DR0E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158347_k127_1250850_6	1229780.BN381_80160	6.697e-33	134.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,3UWTI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158347_k127_12588_15	1463936.JOJI01000058_gene6134	2.305e-46	188.0	COG3899@1|root,COG3903@1|root,COG3899@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158347_k127_12588_2	1380390.JIAT01000009_gene1628	5.531e-123	434.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_12588_26	313589.JNB_00410	4.873e-23	111.0	2EVIQ@1|root,33NYW@2|Bacteria,2IIIZ@201174|Actinobacteria,4FHQ3@85021|Intrasporangiaceae	201174|Actinobacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
SRR25158347_k127_12588_8	710686.Mycsm_01248	5.8e-94	322.0	28KRZ@1|root,2ZA9F@2|Bacteria,2HAAG@201174|Actinobacteria,232GS@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_12588_7	258533.BN977_03947	5.026e-96	327.0	COG3687@1|root,COG3687@2|Bacteria,2HD7U@201174|Actinobacteria,235PN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
SRR25158347_k127_12588_14	1206741.BAFX01000017_gene7233	5.197e-54	201.0	COG1309@1|root,COG1309@2|Bacteria,2GKYG@201174|Actinobacteria,4FXWT@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_12588_25	1283283.ATXA01000005_gene2169	2.377e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,2IMUX@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158347_k127_12588_19	1449044.JMLE01000028_gene264	9.924e-33	133.0	2DWY1@1|root,342G1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_12588_27	399795.CtesDRAFT_PD4686	6.918e-23	102.0	COG0346@1|root,COG0346@2|Bacteria,1RABQ@1224|Proteobacteria,2VS4J@28216|Betaproteobacteria,4AHTQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_12588_3	313606.M23134_06970	1.154e-119	394.0	COG3568@1|root,COG3568@2|Bacteria,4NV25@976|Bacteroidetes	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158347_k127_12588_32	1295642.H839_10478	9.9e-12	72.0	298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1WE67@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
SRR25158347_k127_12588_33	397278.JOJN01000018_gene3510	9.381e-07	53.0	COG3462@1|root,COG3462@2|Bacteria,2I22B@201174|Actinobacteria,4DWE1@85009|Propionibacteriales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_12588_12	36809.MAB_3339	5.159e-76	263.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,2346E@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_12588_11	1193181.BN10_140055	7.375e-81	291.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4FEG6@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	tcsS4	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_12588_9	1121377.KB906398_gene2488	3.493e-83	282.0	2AAWD@1|root,3109H@2|Bacteria	2|Bacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158347_k127_12588_18	1121019.AUMN01000038_gene22	2.398e-33	139.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_12588_35	1297570.MESS4_150047	1.093e-05	54.0	2FBK1@1|root,343R7@2|Bacteria,1NY88@1224|Proteobacteria,2UTP6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_12588_1	765698.Mesci_6352	1.75e-129	428.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,43J11@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158347_k127_12588_34	491916.RHECIAT_CH0001172	1.358e-06	55.0	2C1P2@1|root,313J0@2|Bacteria,1PUR4@1224|Proteobacteria,2V6A0@28211|Alphaproteobacteria,4BGMC@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158347_k127_12588_0	103733.JNYO01000043_gene5945	3.112e-141	483.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria,4DY9X@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_12588_29	1184609.KILIM_019_00150	7.476e-20	100.0	COG1309@1|root,COG1309@2|Bacteria,2GNBI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158347_k127_12588_4	1122182.KB903838_gene4017	1.264e-112	388.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DC7Y@85008|Micromonosporales	201174|Actinobacteria	S	ABC1 family	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
SRR25158347_k127_12588_5	1227487.C474_06307	4.669e-112	376.0	COG1266@1|root,arCOG02768@2157|Archaea,2XXDG@28890|Euryarchaeota,23VZI@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158347_k127_12588_28	1041522.MCOL_V208885	1.206e-20	102.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,232ZY@1762|Mycobacteriaceae	201174|Actinobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_12588_21	196162.Noca_2898	1.874e-29	124.0	2DSM3@1|root,33GM1@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_12588_13	883069.HMPREF9238_00274	1.556e-58	213.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4D3D1@85005|Actinomycetales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158347_k127_12588_6	1173020.Cha6605_0968	1.126e-102	346.0	COG2267@1|root,COG2267@2|Bacteria,1G771@1117|Cyanobacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_12588_17	240015.ACP_0708	2.183e-34	143.0	2B4YW@1|root,31XRX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_12588_10	102129.Lepto7375DRAFT_0220	4.649e-82	295.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158347_k127_12588_20	1229780.BN381_220038	4.797e-32	132.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
SRR25158347_k127_12588_30	405948.SACE_6120	1.161e-17	95.0	2F2DM@1|root,33VBA@2|Bacteria,2HHW0@201174|Actinobacteria,4E60Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
SRR25158347_k127_12588_22	1348663.KCH_49190	1.474e-28	119.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria,2M5BG@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158347_k127_12588_16	1313172.YM304_13730	1.318e-40	154.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_1259987_6	1121924.ATWH01000009_gene55	2.34e-55	202.0	COG1881@1|root,COG1881@2|Bacteria,2HT7J@201174|Actinobacteria,4FSAR@85023|Microbacteriaceae	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP
SRR25158347_k127_1259987_2	1463885.KL578359_gene10048	5.609e-94	314.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	tipA	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
SRR25158347_k127_1259987_10	675635.Psed_5109	8.877e-19	99.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2GKCY@201174|Actinobacteria,4EB4D@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
SRR25158347_k127_1259987_0	1122611.KB903986_gene3995	3.706e-226	709.0	COG0044@1|root,COG0044@2|Bacteria,2GKEC@201174|Actinobacteria,4EMQV@85012|Streptosporangiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158347_k127_1259987_4	2002.JOEQ01000005_gene3805	2.151e-78	270.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4EP9K@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158347_k127_1259987_3	1121946.AUAX01000007_gene2855	6.806e-93	316.0	COG4188@1|root,COG4188@2|Bacteria,2I8YA@201174|Actinobacteria,4DCF2@85008|Micromonosporales	201174|Actinobacteria	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,DLH
SRR25158347_k127_1259987_9	2002.JOEQ01000005_gene3811	1.729e-30	138.0	2BFHU@1|root,329BM@2|Bacteria,2IEQY@201174|Actinobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1259987_8	35754.JNYJ01000016_gene9327	2.86e-46	183.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158347_k127_1259987_7	1206720.BAFQ01000295_gene6480	5.315e-52	194.0	2CHK1@1|root,2ZBVE@2|Bacteria,2IC9S@201174|Actinobacteria,4FZYA@85025|Nocardiaceae	201174|Actinobacteria	S	Red chlorophyll catabolite reductase (RCC reductase)	-	-	-	-	-	-	-	-	-	-	-	-	RCC_reductase
SRR25158347_k127_1259987_1	479432.Sros_6618	2.633e-206	662.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EG8G@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_1259987_5	479432.Sros_6336	2.195e-72	253.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4EK0J@85012|Streptosporangiales	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
SRR25158347_k127_1314863_3	1137799.GZ78_07095	4.385e-17	80.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RS70@1236|Gammaproteobacteria,1XNSH@135619|Oceanospirillales	135619|Oceanospirillales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_1314863_0	208439.AJAP_11990	6.995e-116	387.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4E0CG@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.8.1.20	ko:K22347	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
SRR25158347_k127_1314863_1	177439.DP3059	4.237e-113	394.0	COG0038@1|root,COG0517@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0569@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
SRR25158347_k127_1314863_2	47839.CCAU010000008_gene2049	9.501e-52	202.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1,cNMP_binding
SRR25158347_k127_1320115_41	349102.Rsph17025_2161	3.703e-07	63.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,1FAYA@1060|Rhodobacter	28211|Alphaproteobacteria	S	PQQ-like domain	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
SRR25158347_k127_1320115_44	455632.SGR_4136	3.019e-05	56.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2GIV0@201174|Actinobacteria,417VD@629295|Streptomyces griseus group	201174|Actinobacteria	KLT	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3,Pkinase
SRR25158347_k127_1320115_22	1380347.JNII01000009_gene2071	2.303e-52	198.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4ERDK@85013|Frankiales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158347_k127_1320115_38	661478.OP10G_3165	1.398e-16	94.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1320115_24	1206725.BAFU01000055_gene1506	6.097e-43	159.0	COG1393@1|root,COG1393@2|Bacteria,2IHRP@201174|Actinobacteria,4G2H9@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRR25158347_k127_1320115_40	713587.THITH_01130	1.962e-12	70.0	2CC2C@1|root,32U71@2|Bacteria,1N3IW@1224|Proteobacteria,1SRG1@1236|Gammaproteobacteria,1X1G5@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1320115_25	402881.Plav_1338	1.577e-41	155.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2UEV4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158347_k127_1320115_18	1128421.JAGA01000003_gene3532	3.326e-62	224.0	COG5032@1|root,COG5032@2|Bacteria,2NR1S@2323|unclassified Bacteria	2|Bacteria	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
SRR25158347_k127_1320115_31	926550.CLDAP_03430	1.546e-26	115.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158347_k127_1320115_21	1128421.JAGA01000003_gene3534	6.619e-53	193.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158347_k127_1320115_20	1265310.CCBD010000065_gene909	1.853e-53	207.0	COG3876@1|root,COG3876@2|Bacteria,2GJ19@201174|Actinobacteria,236UN@1762|Mycobacteriaceae	201174|Actinobacteria	S	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158347_k127_1320115_27	1121938.AUDY01000012_gene3779	1.983e-38	167.0	COG0741@1|root,COG2247@1|root,COG0741@2|Bacteria,COG2247@2|Bacteria,1UYN6@1239|Firmicutes,4HC51@91061|Bacilli,3NF4E@45667|Halobacillus	91061|Bacilli	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,SH3_3,SLH,SLT
SRR25158347_k127_1320115_3	479433.Caci_8092	1.72e-205	653.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158347_k127_1320115_45	1040989.AWZU01000011_gene4136	0.000384	52.0	COG3391@1|root,COG3391@2|Bacteria,1N25Z@1224|Proteobacteria,2TUAK@28211|Alphaproteobacteria,3JUD4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PQQ-like domain	MA20_01585	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2,PQQ_2
SRR25158347_k127_1320115_42	525909.Afer_1115	3.782e-07	60.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1320115_15	525904.Tter_2549	1.244e-73	263.0	COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria	2|Bacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
SRR25158347_k127_1320115_16	1894.JOER01000011_gene2071	4.414e-71	252.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_1320115_36	1171373.PACID_21590	3.093e-18	89.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4DVJV@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158347_k127_1320115_9	1120934.KB894413_gene3368	4.027e-93	323.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4DXE1@85010|Pseudonocardiales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158347_k127_1320115_29	641491.DND132_2356	2.548e-32	132.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,42UZH@68525|delta/epsilon subdivisions,2WR2R@28221|Deltaproteobacteria,2MDR0@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158347_k127_1320115_13	1254432.SCE1572_36775	5.882e-78	276.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158347_k127_1320115_28	644283.Micau_4845	3.136e-36	145.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4DCVM@85008|Micromonosporales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158347_k127_1320115_7	471852.Tcur_3247	6.796e-125	427.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4EFKP@85012|Streptosporangiales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158347_k127_1320115_30	1429851.X548_14085	8.093e-32	134.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1X36H@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158347_k127_1320115_11	1380356.JNIK01000001_gene2237	1.444e-88	319.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4ERI5@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158347_k127_1320115_14	1050202.KB913024_gene2351	7.128e-77	270.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4085Q@622450|Actinopolysporales	201174|Actinobacteria	K	HrcA protein C terminal domain	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR25158347_k127_1320115_43	1121385.AQXW01000004_gene2356	2.651e-05	53.0	2DPPE@1|root,332VJ@2|Bacteria,2I19Z@201174|Actinobacteria,1ZW5A@145357|Dermacoccaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158347_k127_1320115_10	1313172.YM304_28400	1.081e-89	316.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158347_k127_1320115_4	134676.ACPL_1298	1.408e-160	521.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DA13@85008|Micromonosporales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158347_k127_1320115_34	1121438.JNJA01000020_gene2717	5.343e-20	98.0	COG4803@1|root,COG4803@2|Bacteria,1RAJ2@1224|Proteobacteria,42RBR@68525|delta/epsilon subdivisions,2WN5K@28221|Deltaproteobacteria,2MAEW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158347_k127_1320115_23	1179773.BN6_07170	3.735e-50	196.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
SRR25158347_k127_1320115_8	1123024.AUII01000008_gene1858	5.294e-100	339.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DXMC@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158347_k127_1320115_1	269800.Tfu_0829	3.976e-250	793.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4EGDX@85012|Streptosporangiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158347_k127_1320115_33	1451261.AS96_01780	1.453e-20	94.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4FPN2@85023|Microbacteriaceae	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158347_k127_1320115_0	1380390.JIAT01000010_gene3567	0.0	1121.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158347_k127_1320115_32	1224163.B841_09970	9.477e-22	106.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,22K21@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158347_k127_1320115_12	685727.REQ_29610	1.089e-85	315.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4FWP3@85025|Nocardiaceae	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158347_k127_1320115_26	471853.Bcav_1737	1.26e-38	153.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158347_k127_1320115_19	926569.ANT_22980	2.323e-54	202.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158347_k127_1320115_17	749414.SBI_01055	1.062e-64	238.0	COG2267@1|root,COG2267@2|Bacteria,2I3E8@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_1320115_2	1089553.Tph_c21390	2.946e-248	799.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158347_k127_1320115_37	1296415.JACC01000076_gene2836	2.422e-17	91.0	COG4859@1|root,COG4859@2|Bacteria,4NTK6@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185
SRR25158347_k127_1320115_35	222534.KB893741_gene2882	2.103e-19	96.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4ESR0@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_1320115_46	391589.RGAI101_2991	0.0006113	52.0	COG2373@1|root,COG2373@2|Bacteria,1QV7E@1224|Proteobacteria,2TWCD@28211|Alphaproteobacteria,2P2MY@2433|Roseobacter	28211|Alphaproteobacteria	S	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
SRR25158347_k127_1320115_6	234267.Acid_2468	2.105e-126	415.0	COG2072@1|root,COG2072@2|Bacteria,3Y8S2@57723|Acidobacteria	57723|Acidobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	-
SRR25158347_k127_1320115_5	164757.Mjls_0414	8.448e-152	502.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,233VG@1762|Mycobacteriaceae	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158347_k127_1320115_39	1476583.DEIPH_ctg103orf0006	4.102e-14	76.0	COG0500@1|root,COG2226@2|Bacteria,1WN1J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_1375714_5	749414.SBI_02003	9.596e-38	145.0	2C57D@1|root,2Z7RS@2|Bacteria,2GNIJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SRR25158347_k127_1375714_3	298655.KI912266_gene2059	1.061e-52	194.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4ESJ1@85013|Frankiales	201174|Actinobacteria	Q	Superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158347_k127_1375714_10	446471.Xcel_1836	2.42e-12	78.0	COG0681@1|root,COG0681@2|Bacteria,2GXS7@201174|Actinobacteria	201174|Actinobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158347_k127_1375714_8	981369.JQMJ01000004_gene5636	2.444e-20	102.0	COG1051@1|root,COG1051@2|Bacteria,2INBQ@201174|Actinobacteria,2NIH7@228398|Streptacidiphilus	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_1375714_6	1313172.YM304_21390	1.125e-26	121.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25,Methyltransf_31
SRR25158347_k127_1375714_0	1463856.JOHY01000002_gene1365	2.975e-160	520.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158347_k127_1375714_9	345341.KUTG_05551	1.138e-16	85.0	2E7YB@1|root,332CR@2|Bacteria,2IRTP@201174|Actinobacteria,4EBM3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
SRR25158347_k127_1375714_2	518766.Rmar_2662	4.674e-123	408.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1FJ2X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_1375714_1	351607.Acel_0550	1.29e-125	413.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4EUA1@85013|Frankiales	201174|Actinobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158347_k127_1375714_4	649747.HMPREF0083_03030	4.491e-47	173.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,26XEB@186822|Paenibacillaceae	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158347_k127_1375714_7	888050.HMPREF9004_0935	3.323e-21	100.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4D4VA@85005|Actinomycetales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_1383404_23	675635.Psed_5109	5.323e-21	104.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2GKCY@201174|Actinobacteria,4EB4D@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
SRR25158347_k127_1383404_14	247634.GPB2148_1377	8.052e-85	289.0	COG4221@1|root,COG4221@2|Bacteria,1RF5D@1224|Proteobacteria,1S5AC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1383404_12	247634.GPB2148_1486	2.275e-94	332.0	29UH5@1|root,30FU6@2|Bacteria,1NQUP@1224|Proteobacteria,1SKVR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1383404_17	1042377.AFPJ01000008_gene1992	8.299e-63	232.0	2ARTX@1|root,31H5E@2|Bacteria,1NRN2@1224|Proteobacteria,1SKPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1383404_24	35754.JNYJ01000027_gene6140	6.615e-19	99.0	2DQJ9@1|root,3377N@2|Bacteria,2I44B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1383404_0	298655.KI912266_gene6362	6.402e-239	770.0	COG0411@1|root,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_1383404_10	298655.KI912266_gene6363	4.246e-95	343.0	COG0410@1|root,COG0410@2|Bacteria,2IH81@201174|Actinobacteria	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,MFS_1
SRR25158347_k127_1383404_15	35754.JNYJ01000073_gene2554	8.602e-70	258.0	COG0683@1|root,COG0683@2|Bacteria,2HZXR@201174|Actinobacteria,4D9W2@85008|Micromonosporales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_1383404_26	479432.Sros_6614	3.152e-14	84.0	2AIS1@1|root,3198W@2|Bacteria,2IPQH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1383404_13	1121946.AUAX01000007_gene2856	2.426e-85	291.0	2CHK1@1|root,2ZBVE@2|Bacteria,2IC9S@201174|Actinobacteria,4DC4I@85008|Micromonosporales	201174|Actinobacteria	S	Red chlorophyll catabolite reductase (RCC reductase)	-	-	-	-	-	-	-	-	-	-	-	-	RCC_reductase
SRR25158347_k127_1383404_8	1121946.AUAX01000007_gene2854	1.489e-126	430.0	COG4638@1|root,COG4638@2|Bacteria,2GKMV@201174|Actinobacteria,4D9AM@85008|Micromonosporales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	ko:K19982	ko00404,ko01130,map00404,map01130	M00790	R11107	RC01333	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158347_k127_1383404_25	930169.B5T_04252	1.734e-18	97.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,1XMB1@135619|Oceanospirillales	135619|Oceanospirillales	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158347_k127_1383404_18	1051632.TPY_1957	3.478e-62	224.0	COG2513@1|root,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia	186801|Clostridia	GM	phosphoenolpyruvate	prpB	-	4.1.3.30,4.1.3.32	ko:K03417,ko:K20454	ko00640,ko00760,ko01120,map00640,map00760,map01120	-	R00409,R01355	RC00286,RC00287,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
SRR25158347_k127_1383404_3	1121946.AUAX01000007_gene2859	1.688e-149	492.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4D8R8@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158347_k127_1383404_22	1220583.GOACH_05_03220	1.747e-28	119.0	COG3871@1|root,COG3871@2|Bacteria,2IKYK@201174|Actinobacteria,4GE6M@85026|Gordoniaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0030312,GO:0031406,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158347_k127_1383404_9	512565.AMIS_57200	8.141e-102	347.0	COG0654@1|root,COG0654@2|Bacteria,2IBV0@201174|Actinobacteria,4DBW6@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158347_k127_1383404_11	1123319.AUBE01000027_gene4814	8.359e-95	328.0	COG3473@1|root,COG3473@2|Bacteria,2GKP7@201174|Actinobacteria	201174|Actinobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158347_k127_1383404_1	1120949.KB903294_gene3461	2.042e-181	576.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DCB9@85008|Micromonosporales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16,2.8.3.20	ko:K07749,ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158347_k127_1383404_19	35754.JNYJ01000062_gene1484	9.445e-52	209.0	COG0119@1|root,COG1853@1|root,COG0119@2|Bacteria,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria,4DCT5@85008|Micromonosporales	201174|Actinobacteria	E	Flavin reductase like domain	-	-	-	ko:K21185	ko01059,ko01130,map01059,map01130	M00827,M00828,M00832	R11368,R11393	RC00949,RC03431	ko00000,ko00001,ko00002	-	-	-	Flavin_Reduct,HMGL-like
SRR25158347_k127_1383404_27	1382304.JNIL01000001_gene77	1.384e-11	76.0	2DNPA@1|root,32YE5@2|Bacteria,1VHDJ@1239|Firmicutes,4HMXA@91061|Bacilli	91061|Bacilli	S	Stress responsive	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158347_k127_1383404_2	247634.GPB2148_1510	3.817e-158	509.0	COG1960@1|root,COG1960@2|Bacteria,1MW97@1224|Proteobacteria	1224|Proteobacteria	I	acyl-CoA dehydrogenase	MA20_38160	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_1383404_20	1042377.AFPJ01000008_gene1987	1.482e-37	156.0	2BY2Y@1|root,33PDR@2|Bacteria,1NTQC@1224|Proteobacteria,1SMBZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1383404_4	35754.JNYJ01000062_gene1486	2.073e-146	481.0	COG1012@1|root,COG1012@2|Bacteria,2IA0G@201174|Actinobacteria,4DC25@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158347_k127_1383404_7	2002.JOEQ01000005_gene3715	1.43e-132	426.0	COG3473@1|root,COG3473@2|Bacteria,2GKP7@201174|Actinobacteria,4EQYD@85012|Streptosporangiales	201174|Actinobacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158347_k127_1383404_16	247634.GPB2148_1377	1.742e-69	246.0	COG4221@1|root,COG4221@2|Bacteria,1RF5D@1224|Proteobacteria,1S5AC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1383404_29	1108045.GORHZ_209_00320	0.0001933	51.0	COG3631@1|root,COG3631@2|Bacteria,2IM62@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158347_k127_1383404_6	1068978.AMETH_3897	8.143e-133	433.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4E02U@85010|Pseudonocardiales	201174|Actinobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113,5.5.1.1	ko:K01856,ko:K02549	ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220	M00116,M00568	R04031,R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01053,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158347_k127_1383404_21	1453496.AT03_10850	6.829e-29	124.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RPR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	yhiD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158347_k127_1383404_5	1313172.YM304_31940	2.709e-146	476.0	COG0402@1|root,COG0402@2|Bacteria,2GKKM@201174|Actinobacteria	201174|Actinobacteria	F	cytosine deaminase	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
SRR25158347_k127_1383404_28	743718.Isova_0395	4.224e-10	61.0	2BVJQ@1|root,32QXM@2|Bacteria,2H17F@201174|Actinobacteria,4F503@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1405696_17	479432.Sros_6626	7.265e-54	204.0	COG0251@1|root,COG0251@2|Bacteria,2IB5I@201174|Actinobacteria	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158347_k127_1405696_19	479432.Sros_6627	2.724e-50	195.0	COG2030@1|root,COG2030@2|Bacteria,2IMSG@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158347_k127_1405696_25	196162.Noca_4070	1.007e-31	137.0	COG2030@1|root,COG2030@2|Bacteria,2GSW5@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_1405696_3	2002.JOEQ01000005_gene3788	3.537e-150	484.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,4EIRT@85012|Streptosporangiales	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158347_k127_1405696_24	479432.Sros_6630	3.674e-33	145.0	COG1545@1|root,COG1545@2|Bacteria,2GTB8@201174|Actinobacteria	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158347_k127_1405696_1	1122611.KB903944_gene1162	5.023e-180	571.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EI7S@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_1405696_9	1122970.AUHC01000014_gene1161	3.709e-79	270.0	COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,2VG5P@28211|Alphaproteobacteria,2K4F2@204457|Sphingomonadales	204457|Sphingomonadales	Q	Isochorismatase family	-	-	3.5.1.107	ko:K13995	ko00760,ko01120,map00760,map01120	M00622	R03540	RC00950	ko00000,ko00001,ko00002,ko01000	-	-	-	Isochorismatase
SRR25158347_k127_1405696_14	247634.GPB2148_1395	2.685e-56	209.0	COG2043@1|root,COG2043@2|Bacteria	2|Bacteria	C	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SRR25158347_k127_1405696_30	1411123.JQNH01000001_gene2723	1.046e-13	84.0	COG1846@1|root,COG1846@2|Bacteria,1RGZI@1224|Proteobacteria,2UA43@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158347_k127_1405696_32	103733.JNYO01000032_gene1283	9.391e-08	60.0	COG3832@1|root,COG3832@2|Bacteria,2HAK8@201174|Actinobacteria,4E5HM@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_1405696_10	644283.Micau_3754	4.311e-69	241.0	COG1802@1|root,COG1802@2|Bacteria,2IBT4@201174|Actinobacteria,4DG68@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158347_k127_1405696_6	1464048.JNZS01000003_gene1151	7.925e-110	363.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4DARK@85008|Micromonosporales	201174|Actinobacteria	E	HMGL-like	-	-	4.1.3.4,4.1.3.46	ko:K01640,ko:K18314	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090,R10674	RC00502,RC00503,RC01118,RC01205,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158347_k127_1405696_2	479432.Sros_6607	1.784e-159	526.0	COG0388@1|root,COG0388@2|Bacteria,2ICY5@201174|Actinobacteria	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158347_k127_1405696_31	2002.JOEQ01000005_gene3779	4.172e-09	68.0	COG0346@1|root,COG0346@2|Bacteria,2H4FI@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1405696_22	795797.C497_16687	2.613e-43	170.0	COG1250@1|root,arCOG00249@2157|Archaea,2XVWM@28890|Euryarchaeota,23UMT@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158347_k127_1405696_26	1120950.KB892757_gene6419	5.51e-31	126.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158347_k127_1405696_15	66692.ABC1605	4.736e-56	216.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HASB@91061|Bacilli,1ZBBZ@1386|Bacillus	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158347_k127_1405696_13	1510531.JQJJ01000010_gene2021	5.024e-60	218.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TT48@28211|Alphaproteobacteria,3JSZX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158347_k127_1405696_11	1156844.KB891831_gene4523	1.576e-61	232.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158347_k127_1405696_4	547163.BN979_05464	1.813e-143	479.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,23340@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158347_k127_1405696_29	1211814.CAPG01000035_gene1786	3.816e-18	94.0	COG1802@1|root,COG1802@2|Bacteria,1V6GK@1239|Firmicutes,4HIN7@91061|Bacilli,1ZFQP@1386|Bacillus	91061|Bacilli	K	FCD	ydhC	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158347_k127_1405696_5	1125973.JNLC01000010_gene1406	3.96e-117	389.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3JTSN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158347_k127_1405696_7	1437448.AZRT01000129_gene253	6.214e-109	364.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1405696_33	1218074.BAXZ01000016_gene3338	1.44e-05	53.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,2VST8@28216|Betaproteobacteria,1K80R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158347_k127_1405696_12	292459.STH451	3.869e-61	223.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia	186801|Clostridia	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158347_k127_1405696_20	263358.VAB18032_19665	1.355e-45	177.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4D90P@85008|Micromonosporales	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	hpcE	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158347_k127_1405696_21	1268072.PSAB_03710	2.212e-45	175.0	COG3836@1|root,COG3836@2|Bacteria,1UZZG@1239|Firmicutes,4HEP6@91061|Bacilli,26X7G@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158347_k127_1405696_23	1123024.AUII01000010_gene776	6.593e-42	164.0	COG3193@1|root,COG3193@2|Bacteria,2IHWI@201174|Actinobacteria,4EEUW@85010|Pseudonocardiales	201174|Actinobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158347_k127_1405696_0	479433.Caci_5230	1.332e-285	899.0	COG2609@1|root,COG2609@2|Bacteria,2GND8@201174|Actinobacteria	201174|Actinobacteria	C	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE_1	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
SRR25158347_k127_1405696_18	765420.OSCT_0658	7.074e-53	215.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2GBJ0@200795|Chloroflexi,37648@32061|Chloroflexia	2|Bacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_1405696_28	583345.Mmol_0129	2.205e-22	115.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KM09@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,Response_reg
SRR25158347_k127_1405696_16	483219.LILAB_04820	1.701e-54	198.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_1405696_8	797299.HALLA_14880	3.932e-97	336.0	COG0642@1|root,arCOG02360@1|root,arCOG02358@2157|Archaea,arCOG02360@2157|Archaea,2Y7KE@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
SRR25158347_k127_1405696_27	743718.Isova_0395	2.438e-28	123.0	2BVJQ@1|root,32QXM@2|Bacteria,2H17F@201174|Actinobacteria,4F503@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1408006_1	469371.Tbis_1385	3.31e-134	437.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4E0N1@85010|Pseudonocardiales	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158347_k127_1408006_4	1121926.AXWO01000008_gene2888	4.773e-44	168.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4EZW3@85014|Glycomycetales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158347_k127_1408006_0	1177594.MIC448_530063	1.177e-137	451.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1408006_8	926564.KI911686_gene5420	1.019e-27	119.0	2DNTJ@1|root,32Z2U@2|Bacteria,2I8BW@201174|Actinobacteria,4F53G@85017|Promicromonosporaceae	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158347_k127_1408006_9	935839.JAGJ01000030_gene3037	9.652e-13	72.0	COG4118@1|root,COG4118@2|Bacteria,2GTS9@201174|Actinobacteria,4F50Y@85017|Promicromonosporaceae	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158347_k127_1408006_7	1454010.JEOE01000024_gene2658	9.809e-28	119.0	COG1848@1|root,COG1848@2|Bacteria,2IQB5@201174|Actinobacteria,4F1IC@85016|Cellulomonadaceae	201174|Actinobacteria	S	PIN domain	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158347_k127_1408006_6	1123511.KB905846_gene2741	2.332e-37	162.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4H2PJ@909932|Negativicutes	909932|Negativicutes	S	hydrolase family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158347_k127_1408006_3	1122622.ATWJ01000008_gene2903	1.051e-47	196.0	COG2132@1|root,COG2385@1|root,COG2132@2|Bacteria,COG2385@2|Bacteria,2IDP7@201174|Actinobacteria,4FIWI@85021|Intrasporangiaceae	201174|Actinobacteria	Q	sporulation resulting in formation of a cellular spore	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158347_k127_1408006_2	251221.35213566	2.71e-65	252.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1408006_5	1267533.KB906742_gene763	3.157e-38	166.0	COG2133@1|root,COG3386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,3Y9DF@57723|Acidobacteria,2JMMK@204432|Acidobacteriia	204432|Acidobacteriia	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158347_k127_1408754_5	1177594.MIC448_2190012	5.437e-33	142.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1408754_2	338969.Rfer_3895	2.201e-233	745.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158347_k127_1408754_1	472759.Nhal_1244	1.355e-261	824.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158347_k127_1408754_0	867845.KI911784_gene1528	4.813e-282	882.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158347_k127_1408754_3	479434.Sthe_1092	2.499e-99	338.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158347_k127_1431711_2	1122218.KB893653_gene801	6.331e-50	185.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,1JR45@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158347_k127_1431711_3	498761.HM1_0667	1.293e-44	173.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158347_k127_1431711_1	469371.Tbis_3424	3.827e-79	280.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158347_k127_1431711_0	760568.Desku_3200	1.843e-81	279.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158347_k127_1431711_4	512565.AMIS_22170	2.748e-17	88.0	COG1595@1|root,COG1595@2|Bacteria,2IMAP@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SRR25158347_k127_1433515_7	1121468.AUBR01000015_gene2243	7.366e-73	267.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,42EPS@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_1433515_3	134676.ACPL_6625	6.09e-105	355.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DAIZ@85008|Micromonosporales	201174|Actinobacteria	G	Starch synthase catalytic domain	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_1433515_8	1123023.JIAI01000006_gene147	1.613e-61	223.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4DZBZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
SRR25158347_k127_1433515_6	1122138.AQUZ01000108_gene8362	1.599e-75	284.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4DP7U@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158347_k127_1433515_5	105420.BBPO01000091_gene4891	3.037e-84	299.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,2NHCD@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_1433515_11	262724.TT_C0430	6.475e-31	132.0	COG0730@1|root,COG0730@2|Bacteria,1WJ68@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158347_k127_1433515_9	644282.Deba_1890	1.499e-41	169.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	molybdenum cofactor	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158347_k127_1433515_2	1463820.JOGW01000010_gene1120	6.263e-136	441.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158347_k127_1433515_12	290397.Adeh_0777	1.002e-06	59.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
SRR25158347_k127_1433515_0	1146883.BLASA_3889	5.625e-238	751.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4ES55@85013|Frankiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase large subunit	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158347_k127_1433515_1	1382306.JNIM01000001_gene1966	6.22e-152	497.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158347_k127_1433515_4	1179773.BN6_73080	4.063e-103	344.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DZZ0@85010|Pseudonocardiales	201174|Actinobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158347_k127_1433515_10	1050202.KB913024_gene2514	6.034e-40	150.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,407JB@622450|Actinopolysporales	201174|Actinobacteria	I	Beta-ketoacyl synthase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_1442110_16	195250.CM001776_gene2075	7.591e-43	163.0	COG0328@1|root,COG0328@2|Bacteria,1G12J@1117|Cyanobacteria,1GYK3@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158347_k127_1442110_18	479435.Kfla_6032	1.313e-29	132.0	COG0742@1|root,COG0742@2|Bacteria,2I6DB@201174|Actinobacteria,4DWFG@85009|Propionibacteriales	201174|Actinobacteria	L	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_1442110_15	1056816.JAFQ01000004_gene6611	1.695e-45	177.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria,4FVEY@85025|Nocardiaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158347_k127_1442110_0	345341.KUTG_07950	2.832e-218	688.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria,4E00S@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158347_k127_1442110_3	1123023.JIAI01000001_gene6046	4.366e-167	539.0	COG0160@1|root,COG0160@2|Bacteria,2GJNQ@201174|Actinobacteria,4DY4N@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
SRR25158347_k127_1442110_6	479432.Sros_2666	1.774e-143	462.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria,4EHKP@85012|Streptosporangiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158347_k127_1442110_5	1120936.KB907208_gene590	2.593e-145	470.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4EID9@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158347_k127_1442110_4	1463845.JOIG01000009_gene3115	7.301e-167	545.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_1442110_10	1120950.KB892760_gene5785	3.669e-106	366.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4DN21@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158347_k127_1442110_11	1133849.O3I_032855	6.174e-99	344.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4FXSA@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158347_k127_1442110_2	1122622.ATWJ01000007_gene1594	1.711e-188	602.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4FE5I@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158347_k127_1442110_12	1064537.AGSO01000002_gene401	3.532e-93	321.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4FBFG@85020|Dermabacteraceae	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158347_k127_1442110_9	110319.CF8_0231	3.706e-117	395.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4DNTA@85009|Propionibacteriales	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158347_k127_1442110_1	391615.ABSJ01000042_gene2272	3.786e-208	655.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J8WH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	iYL1228.KPN_02462	AdoHcyase,AdoHcyase_NAD
SRR25158347_k127_1442110_13	710111.FraQA3DRAFT_5644	8.645e-65	230.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4EVRP@85013|Frankiales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158347_k127_1442110_8	215803.DB30_4004	3.365e-117	384.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158347_k127_1442110_7	264462.Bd2310	2.423e-117	400.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2MT1N@213481|Bdellovibrionales,2WJPF@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158347_k127_1442110_17	543632.JOJL01000007_gene5246	1.901e-39	160.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4D924@85008|Micromonosporales	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_1442110_23	1123321.KB905824_gene4453	4.509e-10	69.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158347_k127_1442110_20	1146883.BLASA_1163	5.808e-27	115.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4ESZD@85013|Frankiales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158347_k127_1442110_24	337191.KTR9_1135	3.399e-08	60.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4GDRI@85026|Gordoniaceae	201174|Actinobacteria	K	Cold shock protein domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158347_k127_1442110_21	1122609.AUGT01000012_gene4255	1.632e-26	122.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4DRBM@85009|Propionibacteriales	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158347_k127_1442110_19	1283299.AUKG01000001_gene1984	1.353e-29	132.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158347_k127_1442110_14	1089453.GOSPT_034_00140	1.265e-53	206.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4GC77@85026|Gordoniaceae	201174|Actinobacteria	G	Inositol monophosphatase family	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158347_k127_1442110_22	298654.FraEuI1c_3652	1.359e-15	78.0	COG0815@1|root,COG1215@1|root,COG0815@2|Bacteria,COG1215@2|Bacteria,2GJ9F@201174|Actinobacteria,4ERH9@85013|Frankiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158347_k127_1503772_18	397278.JOJN01000002_gene53	5.713e-07	53.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4DRTJ@85009|Propionibacteriales	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158347_k127_1503772_10	1229780.BN381_420008	3.137e-54	201.0	COG0368@1|root,COG0368@2|Bacteria	2|Bacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158347_k127_1503772_6	266117.Rxyl_0647	4.219e-96	344.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4CQ14@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
SRR25158347_k127_1503772_7	196162.Noca_3038	1.294e-71	248.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4DUSX@85009|Propionibacteriales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158347_k127_1503772_11	369723.Strop_1611	8.597e-42	155.0	COG2920@1|root,COG2920@2|Bacteria,2IQB2@201174|Actinobacteria,4DJKP@85008|Micromonosporales	201174|Actinobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
SRR25158347_k127_1503772_16	926550.CLDAP_11610	1.38e-23	107.0	COG2427@1|root,COG2427@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
SRR25158347_k127_1503772_1	1385519.N801_12760	1.423e-206	656.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4FFV5@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRR25158347_k127_1503772_15	926550.CLDAP_11630	3.281e-26	119.0	COG2452@1|root,COG4936@1|root,COG2452@2|Bacteria,COG4936@2|Bacteria	2|Bacteria	KT	Sensory domain found in PocR	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HTH_17,PocR
SRR25158347_k127_1503772_14	743718.Isova_2611	1.275e-27	119.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4F4W7@85017|Promicromonosporaceae	201174|Actinobacteria	K	Cold shock protein domain	scoF4	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158347_k127_1503772_8	378806.STAUR_0404	8.882e-64	232.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42RF4@68525|delta/epsilon subdivisions,2WPIV@28221|Deltaproteobacteria,2Z31U@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	glkA	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158347_k127_1503772_13	1380390.JIAT01000009_gene2069	2.141e-36	149.0	COG0697@1|root,COG0697@2|Bacteria,2I9E0@201174|Actinobacteria,4CPT5@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_1503772_4	797114.C475_20932	6.222e-105	354.0	COG1228@1|root,arCOG00696@2157|Archaea,2XUHH@28890|Euryarchaeota,23U5Z@183963|Halobacteria	183963|Halobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158347_k127_1503772_0	266117.Rxyl_0583	2.274e-263	845.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4CRM0@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158347_k127_1503772_3	446470.Snas_3094	2.416e-152	511.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4EY11@85014|Glycomycetales	201174|Actinobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158347_k127_1503772_9	1382359.JIAL01000001_gene2084	1.966e-56	215.0	COG0010@1|root,COG0010@2|Bacteria,3Y5KF@57723|Acidobacteria,2JNH5@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR25158347_k127_1503772_5	1192034.CAP_6685	2.229e-97	335.0	COG0477@1|root,COG2814@2|Bacteria,1PFB3@1224|Proteobacteria,42N9W@68525|delta/epsilon subdivisions,2WJW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1503772_17	391625.PPSIR1_41739	5.887e-17	95.0	COG3356@1|root,COG3356@2|Bacteria,1Q66U@1224|Proteobacteria,4358C@68525|delta/epsilon subdivisions,2WZJF@28221|Deltaproteobacteria,2Z29I@29|Myxococcales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158347_k127_1503772_12	1280950.HJO_10214	1.128e-37	153.0	COG3818@1|root,COG3818@2|Bacteria,1RG7T@1224|Proteobacteria,2U8S8@28211|Alphaproteobacteria,43Y2B@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) family	-	-	-	ko:K06977	-	-	-	-	ko00000	-	-	-	Acetyltransf_1
SRR25158347_k127_1503772_2	1123320.KB889562_gene6853	3.539e-181	587.0	COG2170@1|root,COG2170@2|Bacteria,2GKCT@201174|Actinobacteria	201174|Actinobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158347_k127_1514412_1	351607.Acel_2052	3.935e-70	247.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2I98G@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1514412_5	1122247.C731_2268	8.582e-42	171.0	COG1503@1|root,COG1503@2|Bacteria,2IJI5@201174|Actinobacteria,236IA@1762|Mycobacteriaceae	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1514412_4	525368.HMPREF0591_5878	1.686e-49	190.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,232QT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158347_k127_1514412_9	1033743.CAES01000011_gene4423	3.034e-33	143.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,26RKA@186822|Paenibacillaceae	91061|Bacilli	T	Belongs to the peptidase S16 family	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158347_k127_1514412_2	525904.Tter_1254	4.11e-69	259.0	COG0512@1|root,COG0512@2|Bacteria,2NPBY@2323|unclassified Bacteria	2|Bacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.4.2.18,2.6.1.85,4.1.3.27	ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158347_k127_1514412_0	1121430.JMLG01000007_gene2533	1.314e-96	350.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,260H6@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_1514412_3	1136417.AZWE01000002_gene3582	6.574e-66	253.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4D8QG@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158347_k127_1514412_8	526225.Gobs_0839	3.16e-34	141.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4ESQZ@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158347_k127_1514412_14	446466.Cfla_0020	1.126e-06	57.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4F1I0@85016|Cellulomonadaceae	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
SRR25158347_k127_1514412_15	1236902.ANAS01000039_gene4439	2.93e-06	54.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158347_k127_1514412_11	1101190.ARWB01000001_gene454	2.524e-26	118.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,36XEB@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Domain of unknown function (DUF4118)	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR25158347_k127_1514412_10	521393.JH806634_gene1986	6.349e-28	116.0	COG2337@1|root,COG2337@2|Bacteria,2GS6G@201174|Actinobacteria	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
SRR25158347_k127_1514412_13	246196.MSMEI_6241	9.805e-20	98.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria,234ME@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_1514412_6	479433.Caci_6568	4.102e-41	173.0	COG2247@1|root,COG3291@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.24.3	ko:K01387,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042	-	-	-	Beta_helix,CHU_C,CW_binding_2,DUF11,MAM,PKD,fn3
SRR25158347_k127_1514412_7	82654.Pse7367_1858	7.174e-36	156.0	COG2931@1|root,COG2931@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
SRR25158347_k127_1514412_12	1043205.AFYF01000001_gene88	3.31e-24	109.0	COG0737@1|root,COG2247@1|root,COG0737@2|Bacteria,COG2247@2|Bacteria,2GKC3@201174|Actinobacteria,4FEPR@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158347_k127_1530699_32	1210046.B277_07855	8.116e-09	62.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4FFV2@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158347_k127_1530699_22	222534.KB893761_gene3547	4.776e-48	181.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4ESWI@85013|Frankiales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_1530699_3	1054860.KB913030_gene2353	6.885e-113	372.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158347_k127_1530699_30	67332.FM21_03855	4.389e-20	105.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria	201174|Actinobacteria	H	PFAM thiamineS protein	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158347_k127_1530699_2	1121033.AUCF01000011_gene1823	4.746e-113	377.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2TT7U@28211|Alphaproteobacteria,2JQ7G@204441|Rhodospirillales	204441|Rhodospirillales	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158347_k127_1530699_19	509190.Cseg_1821	4.095e-53	209.0	COG0613@1|root,COG0613@2|Bacteria,1MXJ5@1224|Proteobacteria,2U1RY@28211|Alphaproteobacteria,2KF71@204458|Caulobacterales	204458|Caulobacterales	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1530699_21	1449068.JMLQ01000009_gene3665	2.407e-48	177.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria,4G16Y@85025|Nocardiaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	-	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158347_k127_1530699_28	512565.AMIS_9410	1.026e-27	120.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4DCI4@85008|Micromonosporales	201174|Actinobacteria	S	Mov34 MPN PAD-1 family	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158347_k127_1530699_10	1158182.KB905022_gene986	7.067e-80	274.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RQID@1236|Gammaproteobacteria,1WXW3@135613|Chromatiales	135613|Chromatiales	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158347_k127_1530699_31	1211815.CBYP010000063_gene1915	1.473e-15	85.0	2B4JS@1|root,31XBZ@2|Bacteria,2GYSC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1530699_25	479432.Sros_8781	1.429e-36	148.0	COG1595@1|root,COG1595@2|Bacteria,2IRNG@201174|Actinobacteria,4EJSS@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_1530699_9	469383.Cwoe_5791	1.846e-85	292.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158347_k127_1530699_16	1463881.KL591005_gene6125	6.391e-62	229.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158347_k127_1530699_23	1464048.JNZS01000009_gene5881	2.59e-44	167.0	COG1514@1|root,COG1514@2|Bacteria,2IKSA@201174|Actinobacteria,4DER1@85008|Micromonosporales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158347_k127_1530699_27	1122609.AUGT01000002_gene3987	9.947e-33	142.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria,4DQN6@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRR25158347_k127_1530699_11	67352.JODS01000001_gene529	1.827e-79	291.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158347_k127_1530699_13	469383.Cwoe_1283	4.511e-65	233.0	COG0189@1|root,COG0189@2|Bacteria,2HI2Z@201174|Actinobacteria,4CT1T@84995|Rubrobacteria	84995|Rubrobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRR25158347_k127_1530699_8	330214.NIDE0147	5.826e-87	300.0	COG2326@1|root,COG2326@2|Bacteria,3J111@40117|Nitrospirae	40117|Nitrospirae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158347_k127_1530699_20	1480694.DC28_10945	1.538e-51	201.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SRR25158347_k127_1530699_0	391625.PPSIR1_41409	3.39e-159	510.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	2.6.1.17,2.6.1.88	ko:K14267,ko:K14287	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475,R08618	RC00006,RC00025	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_1530699_6	1313172.YM304_02550	2.682e-93	316.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria	201174|Actinobacteria	E	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158347_k127_1530699_12	1068978.AMETH_5966	1.6e-67	248.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4DYST@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_1530699_7	530564.Psta_3878	1.079e-88	303.0	COG1398@1|root,COG1398@2|Bacteria,2IZ45@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158347_k127_1530699_26	43989.cce_4497	1.924e-35	146.0	COG0483@1|root,COG0483@2|Bacteria,1G10S@1117|Cyanobacteria,3KG56@43988|Cyanothece	1117|Cyanobacteria	G	inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158347_k127_1530699_29	1158050.KB895464_gene3627	6.108e-24	106.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158347_k127_1530699_33	744980.TRICHSKD4_4193	6.585e-08	63.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158347_k127_1530699_24	28042.GU90_16420	3.774e-43	164.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4E2R0@85010|Pseudonocardiales	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158347_k127_1530699_34	471853.Bcav_3954	0.0002508	54.0	2ESVG@1|root,33KDV@2|Bacteria,2IA6T@201174|Actinobacteria	201174|Actinobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158347_k127_1530699_18	429009.Adeg_0473	1.15e-53	204.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_1530699_14	58123.JOFJ01000004_gene1807	3.135e-63	228.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4EFIZ@85012|Streptosporangiales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158347_k127_1530699_4	1003195.SCAT_1991	3.808e-96	321.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158347_k127_1530699_1	1122247.C731_1452	3.066e-127	417.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z5@201174|Actinobacteria,234K9@1762|Mycobacteriaceae	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158347_k127_1530699_15	1385518.N798_06935	3.456e-62	226.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4FGD7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158347_k127_1530699_17	675635.Psed_2003	2.458e-60	223.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4E0FZ@85010|Pseudonocardiales	201174|Actinobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158347_k127_1530699_5	644282.Deba_0224	1.596e-95	319.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158347_k127_1533132_0	869210.Marky_1871	6.516e-122	411.0	COG0155@1|root,COG0155@2|Bacteria,1WIU8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Nitrite and sulphite reductase 4Fe-4S	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158347_k127_1533132_2	1150864.MILUP08_46348	1.174e-24	118.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1533132_1	543632.JOJL01000005_gene4760	6.281e-48	196.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRR25158347_k127_1533132_3	710686.Mycsm_00677	4.106e-21	105.0	COG2852@1|root,COG2852@2|Bacteria,2GKCY@201174|Actinobacteria,236GB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158347_k127_1534383_5	1348338.ADILRU_1125	1.48e-12	73.0	COG0791@1|root,COG2247@1|root,COG0791@2|Bacteria,COG2247@2|Bacteria,2IK12@201174|Actinobacteria	201174|Actinobacteria	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
SRR25158347_k127_1534383_1	1133850.SHJG_2338	1.481e-88	304.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_1534383_4	1122611.KB904007_gene7916	4.076e-27	116.0	COG4911@1|root,COG4911@2|Bacteria,2IMEK@201174|Actinobacteria,4EJXV@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158347_k127_1534383_0	1463934.JOCF01000104_gene7403	0.0	1101.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria	201174|Actinobacteria	C	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158347_k127_1534383_3	272134.KB731325_gene549	7.507e-35	147.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_1534383_2	1048339.KB913029_gene2189	5.333e-69	241.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4ESKC@85013|Frankiales	201174|Actinobacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	Hao	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158347_k127_1551606_19	935567.JAES01000016_gene1546	4.303e-68	240.0	COG1365@1|root,COG1365@2|Bacteria,1R62V@1224|Proteobacteria,1S2JY@1236|Gammaproteobacteria,1X5D9@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1551606_15	1234364.AMSF01000063_gene2247	2.195e-84	297.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1X37K@135614|Xanthomonadales	135614|Xanthomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_1551606_14	321327.CYA_1468	2.829e-85	302.0	COG0111@1|root,COG0111@2|Bacteria,1G417@1117|Cyanobacteria,1H2J2@1129|Synechococcus	1117|Cyanobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158347_k127_1551606_27	1313172.YM304_20690	2.124e-51	186.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158347_k127_1551606_16	412597.AEPN01000012_gene2546	3.406e-83	298.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TSHC@28211|Alphaproteobacteria,2PU43@265|Paracoccus	28211|Alphaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158347_k127_1551606_20	42256.RradSPS_0141	3.013e-66	248.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158347_k127_1551606_0	292459.STH2116	4.992e-209	663.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158347_k127_1551606_3	404380.Gbem_2742	8.861e-151	495.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,43TQC@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158347_k127_1551606_32	68219.JNXI01000010_gene5735	6.23e-36	151.0	COG1018@1|root,COG4097@1|root,COG1018@2|Bacteria,COG4097@2|Bacteria,2GJCV@201174|Actinobacteria	201174|Actinobacteria	C	Flavodoxin reductases ferredoxin-NADPH reductases family 1	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,p450
SRR25158347_k127_1551606_25	1229780.BN381_420032	7.001e-52	199.0	COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,3UWYP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158347_k127_1551606_26	1089544.KB912942_gene7538	1.775e-51	195.0	COG3375@1|root,COG3375@2|Bacteria,2I8MV@201174|Actinobacteria,4DZFG@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1551606_41	1300345.LF41_1129	3.727e-11	70.0	2AT5S@1|root,31IN0@2|Bacteria,1QGAS@1224|Proteobacteria,1TDQ2@1236|Gammaproteobacteria,1XB04@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1551606_43	1298858.AUEL01000026_gene3435	1.39e-05	54.0	2EK0M@1|root,33DR5@2|Bacteria,1NKNS@1224|Proteobacteria,2UNJZ@28211|Alphaproteobacteria,43P8N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRR25158347_k127_1551606_38	1122939.ATUD01000007_gene1941	1.495e-29	130.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria,4CQEV@84995|Rubrobacteria	84995|Rubrobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158347_k127_1551606_5	1214242.B446_11425	2.675e-124	414.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_1551606_12	1214101.BN159_4406	1.569e-91	319.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158347_k127_1551606_4	1122182.KB903813_gene2050	4.701e-130	440.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DA2N@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158347_k127_1551606_8	1041522.MCOL_V218378	2.426e-109	366.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,234HF@1762|Mycobacteriaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158347_k127_1551606_37	1184609.KILIM_004_01450	1.001e-31	133.0	COG0589@1|root,COG0589@2|Bacteria,2IR3G@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158347_k127_1551606_31	1449058.JQKT01000009_gene189	1.382e-36	154.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1551606_2	485913.Krac_2637	9.273e-153	503.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158347_k127_1551606_36	1449058.JQKT01000009_gene191	5.811e-32	139.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1551606_34	1449058.JQKT01000009_gene191	3.095e-33	145.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1551606_33	1177594.MIC448_2190012	1.685e-35	150.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1551606_29	1177594.MIC448_2190012	4.444e-43	181.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_1551606_18	1961.JOAK01000024_gene3660	3.974e-73	256.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158347_k127_1551606_11	1292020.H483_0109435	2.164e-104	355.0	COG0477@1|root,COG2814@2|Bacteria,2I9K2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1551606_17	1242864.D187_004703	8.211e-76	267.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158347_k127_1551606_30	1907.SGLAU_23245	4.664e-39	157.0	COG1309@1|root,COG1309@2|Bacteria,2GMZ1@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_1551606_24	1150864.MILUP08_43361	5.84e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,2IMGZ@201174|Actinobacteria,4DFBG@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_1551606_10	67373.JOBF01000027_gene1633	2.914e-106	357.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_1551606_40	526225.Gobs_4464	3.208e-13	81.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,4ET64@85013|Frankiales	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158347_k127_1551606_35	1122239.AULS01000007_gene381	4.267e-32	136.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FM3W@85023|Microbacteriaceae	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_1551606_1	222534.KB893672_gene3008	1.053e-188	602.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4ERFK@85013|Frankiales	201174|Actinobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18472	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04386	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans,NUDIX
SRR25158347_k127_1551606_7	216595.PFLU_3199	4.414e-111	376.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria	1224|Proteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158347_k127_1551606_42	999415.HMPREF9943_00385	4.449e-06	53.0	COG0236@1|root,COG0236@2|Bacteria,1VG4C@1239|Firmicutes,3VRX9@526524|Erysipelotrichia	526524|Erysipelotrichia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR25158347_k127_1551606_22	742738.HMPREF9460_00934	1.749e-57	213.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,26846@186813|unclassified Clostridiales	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_1551606_13	1306990.BARG01000066_gene7509	5.381e-88	304.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648,ko:K21788	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082,M00083	R10707,R11671	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158347_k127_1551606_28	644282.Deba_1955	3.011e-44	173.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158347_k127_1551606_6	392499.Swit_0679	2.121e-113	379.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2TR62@28211|Alphaproteobacteria,2K1KR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158347_k127_1551606_21	357808.RoseRS_0220	2.126e-58	215.0	COG0451@1|root,COG0451@2|Bacteria,2GAZF@200795|Chloroflexi,374ZI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD
SRR25158347_k127_1551606_9	1123320.KB889676_gene2915	3.207e-107	357.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158347_k127_1559544_11	58123.JOFJ01000003_gene2030	4.469e-91	305.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4EG3D@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158347_k127_1559544_17	467200.ACFA01000276_gene1244	5.124e-61	225.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158347_k127_1559544_20	35754.JNYJ01000005_gene5432	3.645e-44	171.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4DBJT@85008|Micromonosporales	201174|Actinobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158347_k127_1559544_9	1313172.YM304_22570	7.801e-96	329.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CMPY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158347_k127_1559544_6	656024.FsymDg_3655	1.756e-127	436.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4ERMJ@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158347_k127_1559544_18	106370.Francci3_3574	2.003e-51	201.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4ESD0@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase M50	rip1	GO:0008150,GO:0040007	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158347_k127_1559544_10	1122182.KB903835_gene4594	3.553e-95	319.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
SRR25158347_k127_1559544_5	1064537.AGSO01000009_gene2243	5.024e-133	437.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4FDIV@85020|Dermabacteraceae	201174|Actinobacteria	I	GcpE protein	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158347_k127_1559544_24	1160718.SU9_06000	4.457e-19	95.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158347_k127_1559544_8	1380356.JNIK01000016_gene3869	7.085e-103	351.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4ERKN@85013|Frankiales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158347_k127_1559544_29	644966.Tmar_1017	4.71e-11	74.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WCNN@538999|Clostridiales incertae sedis	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158347_k127_1559544_2	760568.Desku_2543	2.956e-194	637.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158347_k127_1559544_28	469383.Cwoe_3222	2.571e-12	70.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158347_k127_1559544_27	936548.HMPREF1136_0149	1.745e-13	75.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4D5RF@85005|Actinomycetales	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158347_k127_1559544_15	1120958.AULD01000007_gene1178	3.464e-71	251.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4FKEW@85023|Microbacteriaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158347_k127_1559544_12	58123.JOFJ01000003_gene1936	1.019e-81	282.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4EHXD@85012|Streptosporangiales	201174|Actinobacteria	H	Riboflavin kinase	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158347_k127_1559544_22	981369.JQMJ01000004_gene3304	3.274e-37	158.0	COG0454@1|root,COG0456@2|Bacteria,2GY1D@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_1559544_23	1033730.CAHG01000013_gene1393	1.48e-33	131.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DS16@85009|Propionibacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158347_k127_1559544_0	1112204.GPOL_c20610	8.113e-234	752.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4GBHZ@85026|Gordoniaceae	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158347_k127_1559544_7	1122611.KB903982_gene3584	2.157e-120	402.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4EHPV@85012|Streptosporangiales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158347_k127_1559544_21	1133849.O3I_019915	1.984e-37	149.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,4G1EZ@85025|Nocardiaceae	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158347_k127_1559544_16	696281.Desru_1914	3.887e-66	242.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,2607V@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158347_k127_1559544_30	71139.XP_010036957.1	1.609e-06	61.0	KOG4197@1|root,KOG4197@2759|Eukaryota,37Q8H@33090|Viridiplantae,3GFT1@35493|Streptophyta	35493|Streptophyta	S	Pentatricopeptide repeat-containing protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:1901360,GO:1901363	-	ko:K07874	ko05134,map05134	-	-	-	ko00000,ko00001,ko04031,ko04131,ko04147	-	-	-	PPR,PPR_2
SRR25158347_k127_1559544_1	561175.KB894096_gene801	1.013e-197	634.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EFP3@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_1559544_25	356851.JOAN01000001_gene3859	2.28e-17	95.0	COG2755@1|root,COG2755@2|Bacteria,2I9EE@201174|Actinobacteria,4D9ZC@85008|Micromonosporales	201174|Actinobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158347_k127_1559544_14	28042.GU90_04360	4.716e-76	271.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4E5SR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_1559544_3	1313172.YM304_25950	1.154e-190	619.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158347_k127_1559544_26	557598.LHK_03181	4.392e-16	85.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,2KRZB@206351|Neisseriales	206351|Neisseriales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158347_k127_1559544_13	264732.Moth_1068	9.1e-77	267.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,42FSY@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158347_k127_1559544_4	1121342.AUCO01000001_gene2104	1.713e-146	483.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158347_k127_1559544_19	1089455.MOPEL_009_00660	3e-47	186.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4F62Q@85018|Dermatophilaceae	201174|Actinobacteria	D	Ftsk_gamma	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158347_k127_163396_3	479431.Namu_5155	2.499e-07	63.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HTPC@201174|Actinobacteria,4EWPM@85013|Frankiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158347_k127_163396_1	446462.Amir_0828	1.026e-36	147.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,4E048@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_163396_0	525909.Afer_0305	2.037e-139	454.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_163396_2	1463903.JOIZ01000008_gene4412	7.347e-16	91.0	COG3255@1|root,COG3255@2|Bacteria,2GWVN@201174|Actinobacteria	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158347_k127_1635141_9	1463885.KL578377_gene7294	0.0001157	51.0	COG1073@1|root,COG1073@2|Bacteria,2I3YE@201174|Actinobacteria	201174|Actinobacteria	P	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_1635141_2	1300345.LF41_483	5.648e-114	376.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1X3WV@135614|Xanthomonadales	135614|Xanthomonadales	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158347_k127_1635141_1	930169.B5T_01797	3.324e-192	621.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1XISG@135619|Oceanospirillales	135619|Oceanospirillales	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.5	ko:K13777	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158347_k127_1635141_3	1385515.N791_04365	1.137e-63	229.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1X52R@135614|Xanthomonadales	135614|Xanthomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_1635141_5	933262.AXAM01000118_gene2900	8.34e-36	148.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2MJW0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_1635141_7	1298863.AUEP01000005_gene2421	1.114e-20	98.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_1635141_4	469383.Cwoe_3472	1.951e-46	194.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158347_k127_1635141_0	1120936.KB907210_gene5640	1.38e-256	818.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4EH6R@85012|Streptosporangiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158347_k127_1635141_6	479433.Caci_0426	1.643e-29	124.0	COG3871@1|root,COG3871@2|Bacteria,2GWY2@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158347_k127_1635141_8	420662.Mpe_A0097	1.004e-15	76.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,1KNI9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158347_k127_1639037_0	2074.JNYD01000007_gene2129	4.224e-140	455.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4DZB5@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158347_k127_1639037_4	760568.Desku_1990	7.796e-26	123.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,261RC@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
SRR25158347_k127_1639037_1	264732.Moth_1555	3.725e-79	287.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,42FJ5@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158347_k127_1639037_2	411464.DESPIG_02727	5.375e-39	150.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,2MBIR@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158347_k127_1639037_3	211114.JOEF01000010_gene3319	1.391e-30	132.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4DYZ4@85010|Pseudonocardiales	201174|Actinobacteria	E	Creatinase Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158347_k127_1648209_14	1033734.CAET01000042_gene423	4.019e-26	119.0	COG0726@1|root,COG2247@1|root,COG0726@2|Bacteria,COG2247@2|Bacteria,1V827@1239|Firmicutes,4HGM9@91061|Bacilli,1ZFYZ@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158347_k127_1648209_11	1003195.SCAT_3707	5.412e-65	231.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158347_k127_1648209_2	269800.Tfu_2572	3.022e-175	564.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4EGIJ@85012|Streptosporangiales	201174|Actinobacteria	F	AICARFT/IMPCHase bienzyme	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158347_k127_1648209_17	98439.AJLL01000068_gene1519	4.038e-05	53.0	COG2944@1|root,COG2944@2|Bacteria,1GA6E@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158347_k127_1648209_16	401526.TcarDRAFT_2491	1.47e-12	76.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4H8UU@909932|Negativicutes	909932|Negativicutes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158347_k127_1648209_9	1408304.JAHA01000003_gene3345	1.87e-85	292.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,4BXXI@830|Butyrivibrio	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158347_k127_1648209_13	1048339.KB913029_gene4673	5.691e-28	121.0	2E8P5@1|root,3330B@2|Bacteria,2GRP1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1648209_12	1440053.JOEI01000019_gene727	1.643e-33	148.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158347_k127_1648209_5	1122939.ATUD01000009_gene2981	7.077e-126	412.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4CPFH@84995|Rubrobacteria	84995|Rubrobacteria	C	lactate/malate dehydrogenase, alpha/beta C-terminal domain	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158347_k127_1648209_7	1445613.JALM01000051_gene4102	7.373e-109	362.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4E1GX@85010|Pseudonocardiales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158347_k127_1648209_4	485913.Krac_12490	1.275e-129	426.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158347_k127_1648209_10	1313172.YM304_07470	1.319e-78	273.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158347_k127_1648209_0	153721.MYP_1448	9.738e-316	976.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158347_k127_1648209_6	1313172.YM304_07490	2.094e-112	372.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CNED@84992|Acidimicrobiia	84992|Acidimicrobiia	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3
SRR25158347_k127_1648209_15	1279019.ARQK01000061_gene1857	3.438e-25	111.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1WVZG@135613|Chromatiales	135613|Chromatiales	T	phosphate regulon transcriptional regulatory protein PhoB	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_1648209_8	1121019.AUMN01000031_gene3972	1.818e-96	332.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,1W816@1268|Micrococcaceae	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1648209_1	66373.JOFQ01000002_gene4985	1.503e-234	737.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	bhbA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158347_k127_1648209_3	397278.JOJN01000001_gene2858	3.72e-138	457.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4DNPF@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_1652454_24	58123.JOFJ01000001_gene3057	1.526e-64	226.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4EGJ2@85012|Streptosporangiales	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158347_k127_1652454_30	351607.Acel_1305	1.069e-55	200.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4ERK9@85013|Frankiales	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158347_k127_1652454_40	1449976.KALB_2748	1.519e-24	113.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158347_k127_1652454_27	266940.Krad_3006	5.061e-60	216.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158347_k127_1652454_6	471852.Tcur_3015	6.448e-122	406.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4EH29@85012|Streptosporangiales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158347_k127_1652454_4	44060.JODL01000006_gene1492	1.996e-146	481.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158347_k127_1652454_5	222534.KB893694_gene143	1.68e-145	473.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4ERR1@85013|Frankiales	201174|Actinobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158347_k127_1652454_0	351607.Acel_1298	0.0	1376.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4ERGS@85013|Frankiales	201174|Actinobacteria	F	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158347_k127_1652454_15	1380370.JIBA01000013_gene1641	2.809e-83	291.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4FFS3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydroorotate oxidase	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158347_k127_1652454_12	351607.Acel_1296	2.926e-91	312.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4ERIP@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14,1.3.5.2	ko:K00254,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158347_k127_1652454_32	290397.Adeh_3945	1.292e-52	206.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158347_k127_1652454_23	1507.HMPREF0262_02043	2.19e-65	237.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,36ETX@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158347_k127_1652454_39	1120948.KB903240_gene3933	4.05e-30	123.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4E4HM@85010|Pseudonocardiales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1652454_29	64471.sync_2153	1.065e-55	208.0	COG0194@1|root,COG0194@2|Bacteria,1G515@1117|Cyanobacteria,1GZ3I@1129|Synechococcus	1117|Cyanobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158347_k127_1652454_42	469371.Tbis_1361	3.046e-13	81.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4E5KY@85010|Pseudonocardiales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158347_k127_1652454_7	1122611.KB903947_gene1047	2.505e-117	392.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4EFS1@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158347_k127_1652454_2	1121946.AUAX01000008_gene7184	1.135e-159	513.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4D8EK@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158347_k127_1652454_20	390989.JOEG01000012_gene3245	4.23e-71	264.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4DA4R@85008|Micromonosporales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158347_k127_1652454_36	365528.KB891218_gene1519	8.544e-41	161.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4ESF2@85013|Frankiales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158347_k127_1652454_17	1123322.KB904705_gene22	2.322e-81	282.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158347_k127_1652454_19	65497.JODV01000014_gene3259	3.227e-74	267.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4DZAD@85010|Pseudonocardiales	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158347_k127_1652454_22	1298880.AUEV01000008_gene2391	2.021e-65	231.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158347_k127_1652454_14	1464048.JNZS01000019_gene2325	3.533e-85	296.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158347_k127_1652454_18	379066.GAU_1471	1.149e-75	272.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158347_k127_1652454_25	196162.Noca_2448	9.423e-62	218.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4DQ6E@85009|Propionibacteriales	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158347_k127_1652454_3	298654.FraEuI1c_1697	7.096e-156	510.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4ERH4@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158347_k127_1652454_33	1308866.J416_10980	1.304e-52	189.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,470KV@74385|Gracilibacillus	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRR25158347_k127_1652454_34	390989.JOEG01000016_gene5611	4.817e-41	168.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria,4DA7C@85008|Micromonosporales	201174|Actinobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158347_k127_1652454_9	263358.VAB18032_09245	7.308e-105	351.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DAWH@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_1652454_43	101510.RHA1_ro04525	4.183e-12	77.0	2ESVE@1|root,33KDT@2|Bacteria,2I8VG@201174|Actinobacteria,4FUNY@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158347_k127_1652454_8	263358.VAB18032_15145	3.087e-108	368.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4DARG@85008|Micromonosporales	201174|Actinobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158347_k127_1652454_37	390989.JOEG01000007_gene591	1.888e-31	131.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4DF5K@85008|Micromonosporales	201174|Actinobacteria	E	Phosphoribosyl-ATP	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
SRR25158347_k127_1652454_28	40571.JOEA01000031_gene922	3.76e-57	210.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DYUF@85010|Pseudonocardiales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158347_k127_1652454_41	1120950.KB892768_gene5218	4.62e-16	79.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4DSQQ@85009|Propionibacteriales	201174|Actinobacteria	J	Ribosomal protein L35	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158347_k127_1652454_35	1122138.AQUZ01000041_gene7276	7.018e-41	154.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4DQY2@85009|Propionibacteriales	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158347_k127_1652454_31	35754.JNYJ01000001_gene7472	3.506e-53	202.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4DAJB@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158347_k127_1652454_21	73044.JNXP01000004_gene3092	6.886e-71	252.0	COG0642@1|root,COG2205@2|Bacteria,2GMB9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158347_k127_1652454_10	1297581.H919_09588	4.107e-102	344.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,21V8X@150247|Anoxybacillus	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158347_k127_1652454_1	222534.KB893694_gene167	3.851e-160	533.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4ES8F@85013|Frankiales	201174|Actinobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158347_k127_1652454_38	1246995.AFR_36755	3.496e-31	129.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4DMWM@85008|Micromonosporales	201174|Actinobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158347_k127_1652454_11	1200792.AKYF01000027_gene365	1.691e-91	312.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,26QA1@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11190	Semialdhyde_dh,Semialdhyde_dhC
SRR25158347_k127_1652454_16	1496688.ER33_15955	4.751e-82	295.0	COG1364@1|root,COG1364@2|Bacteria,1G1H7@1117|Cyanobacteria,22S9R@167375|Cyanobium	1117|Cyanobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argJ	ArgJ
SRR25158347_k127_1652454_13	512565.AMIS_61560	2.427e-85	309.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4DC1Z@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158347_k127_1652454_26	1121472.AQWN01000001_gene260	6.009e-61	227.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,2606U@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_1657371_1	298653.Franean1_1145	9.045e-162	547.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4ERQY@85013|Frankiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158347_k127_1657371_5	1313172.YM304_29620	2.533e-53	199.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	mscS	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
SRR25158347_k127_1657371_3	1386089.N865_10310	3.184e-94	324.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4FF05@85021|Intrasporangiaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158347_k127_1657371_14	935866.JAER01000001_gene2546	9.638e-06	51.0	2EI4A@1|root,33BVN@2|Bacteria,2GX45@201174|Actinobacteria,4DSKQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1657371_2	572479.Hprae_0917	4.645e-141	471.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WAIA@53433|Halanaerobiales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158347_k127_1657371_13	485913.Krac_3478	1.323e-17	90.0	2DU4Y@1|root,33NY5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1657371_10	1048339.KB913029_gene3511	6.956e-28	118.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4ESVE@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158347_k127_1657371_12	1410665.JNKR01000002_gene1816	3.344e-19	89.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4H5NW@909932|Negativicutes	909932|Negativicutes	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158347_k127_1657371_11	58123.JOFJ01000003_gene2044	1.124e-26	117.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4EJ2M@85012|Streptosporangiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158347_k127_1657371_4	298655.KI912267_gene6707	7.885e-80	277.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4ERT5@85013|Frankiales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158347_k127_1657371_6	477641.MODMU_4415	1.11e-49	183.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4ESVQ@85013|Frankiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158347_k127_1657371_7	298655.KI912267_gene6705	1.279e-46	178.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4ESKU@85013|Frankiales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158347_k127_1657371_0	479434.Sthe_3162	7.12e-176	566.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2G64U@200795|Chloroflexi	200795|Chloroflexi	P	YidE YbjL duplication domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
SRR25158347_k127_1657371_9	1313172.YM304_21910	1.204e-36	147.0	COG1296@1|root,COG1296@2|Bacteria	2|Bacteria	E	L-valine transmembrane transporter activity	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158347_k127_1657371_8	2074.JNYD01000003_gene3504	5.469e-42	162.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E16G@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_16644_1	469383.Cwoe_4762	1.297e-144	485.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CRP4@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158347_k127_16644_4	585531.HMPREF0063_10398	8.376e-108	368.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4DRHN@85009|Propionibacteriales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_16644_2	1229203.KI301992_gene2688	8.084e-114	379.0	COG4177@1|root,COG4177@2|Bacteria,2HFUG@201174|Actinobacteria,3UXQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158347_k127_16644_5	1463825.JNXC01000023_gene4961	1.756e-92	312.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DZD5@85010|Pseudonocardiales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_16644_0	1121272.KB903272_gene442	5.609e-236	747.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DA3R@85008|Micromonosporales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_16644_3	1463825.JNXC01000023_gene4963	1.485e-108	359.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E1TV@85010|Pseudonocardiales	201174|Actinobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_16644_6	1123507.ATVQ01000003_gene783	7.048e-88	297.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,1W9KM@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_1682565_2	1227495.C487_02573	4.042e-17	90.0	COG0647@1|root,COG1051@1|root,arCOG01075@2157|Archaea,arCOG04221@2157|Archaea,2XYZC@28890|Euryarchaeota,23X60@183963|Halobacteria	183963|Halobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
SRR25158347_k127_1682565_3	768671.ThimaDRAFT_0723	1.551e-05	58.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Calx-beta,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
SRR25158347_k127_1682565_0	1227352.C173_32216	1.049e-103	355.0	COG1397@1|root,COG1397@2|Bacteria,1VU5I@1239|Firmicutes,4I6SG@91061|Bacilli,26UQ7@186822|Paenibacillaceae	91061|Bacilli	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
SRR25158347_k127_1682565_1	234267.Acid_2380	9.866e-19	102.0	COG2133@1|root,COG3292@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1906,Glyco_hydro_18,Malectin,PA14,SLH,VCBS
SRR25158347_k127_1682565_4	161528.ED21_20694	0.0001999	50.0	COG4244@1|root,COG4244@2|Bacteria,1NA2H@1224|Proteobacteria,2UF3W@28211|Alphaproteobacteria,2KBQ1@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1692035_9	522306.CAP2UW1_2351	5.579e-41	163.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,2VPWM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
SRR25158347_k127_1692035_5	861299.J421_6132	3.539e-89	315.0	COG0477@1|root,COG2814@2|Bacteria,1ZSUR@142182|Gemmatimonadetes	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158347_k127_1692035_7	43354.JOIJ01000005_gene2259	1.637e-76	267.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DYKF@85010|Pseudonocardiales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158347_k127_1692035_11	1525715.IX54_14475	2.805e-23	110.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2PVP7@265|Paracoccus	28211|Alphaproteobacteria	S	Probable molybdopterin binding domain	cinA1	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158347_k127_1692035_1	1229780.BN381_780010	4.273e-128	422.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria	201174|Actinobacteria	EGP	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158347_k127_1692035_0	585531.HMPREF0063_12247	3.259e-198	628.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4DNFE@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	ccr	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_1692035_10	1298863.AUEP01000008_gene1329	1.904e-29	136.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4DR8M@85009|Propionibacteriales	201174|Actinobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SRR25158347_k127_1692035_4	469371.Tbis_1231	8.162e-90	308.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria,4DXIP@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158347_k127_1692035_2	219305.MCAG_03154	2.056e-112	376.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4D9B0@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158347_k127_1692035_6	405948.SACE_5745	2.933e-77	267.0	COG1120@1|root,COG1120@2|Bacteria,2IA4F@201174|Actinobacteria,4E0AK@85010|Pseudonocardiales	201174|Actinobacteria	HP	ABC-type cobalamin Fe3 -siderophore transport system, ATPase component	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158347_k127_1692035_8	469383.Cwoe_2995	2.483e-44	180.0	COG0566@1|root,COG0566@2|Bacteria,2GJ7P@201174|Actinobacteria	201174|Actinobacteria	J	SpoU rRNA Methylase family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158347_k127_1692035_3	1192034.CAP_4131	2.141e-108	362.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria,2YTTX@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158347_k127_1706872_7	1122611.KB903971_gene2649	1.968e-77	272.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4EGY5@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158347_k127_1706872_6	118168.MC7420_5448	3.034e-79	282.0	COG3608@1|root,COG3608@2|Bacteria,1G167@1117|Cyanobacteria,1H7T8@1150|Oscillatoriales	1117|Cyanobacteria	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
SRR25158347_k127_1706872_15	1121937.AUHJ01000018_gene252	4.584e-27	120.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,467C1@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
SRR25158347_k127_1706872_20	1236902.ANAS01000040_gene4996	1.018e-05	53.0	COG3255@1|root,COG3255@2|Bacteria,2IM6I@201174|Actinobacteria,4EK7N@85012|Streptosporangiales	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158347_k127_1706872_11	1416759.AYMR01000018_gene2132	4.49e-48	181.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4FNXN@85023|Microbacteriaceae	201174|Actinobacteria	H	RibD C-terminal domain	ribD	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158347_k127_1706872_22	269800.Tfu_2036	9.228e-05	53.0	COG3937@1|root,COG3937@2|Bacteria,2GXZ4@201174|Actinobacteria,4EQDZ@85012|Streptosporangiales	201174|Actinobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1706872_9	471852.Tcur_2169	2.96e-68	244.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4EGHU@85012|Streptosporangiales	201174|Actinobacteria	J	FtsJ-like methyltransferase	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158347_k127_1706872_10	446462.Amir_5440	2.7e-58	213.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4DYJH@85010|Pseudonocardiales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158347_k127_1706872_5	1223523.H340_27462	3.14e-105	362.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158347_k127_1706872_0	1120973.AQXL01000132_gene2242	5.696e-166	549.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,277XG@186823|Alicyclobacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158347_k127_1706872_12	586416.GZ22_15165	1.331e-44	165.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158347_k127_1706872_13	1206739.BAGJ01000074_gene6390	1.192e-41	161.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4FXIN@85025|Nocardiaceae	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158347_k127_1706872_1	390989.JOEG01000017_gene6238	2.468e-141	458.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4DA3S@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158347_k127_1706872_17	408672.NBCG_02826	1.259e-14	78.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4DRE5@85009|Propionibacteriales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158347_k127_1706872_4	562970.Btus_1407	1.054e-105	357.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,278UM@186823|Alicyclobacillaceae	91061|Bacilli	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158347_k127_1706872_16	1370121.AUWS01000023_gene1984	2.387e-21	106.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,2330W@1762|Mycobacteriaceae	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158347_k127_1706872_19	390989.JOEG01000026_gene1561	1.071e-06	61.0	2CT9V@1|root,32SSX@2|Bacteria,2HS3F@201174|Actinobacteria,4DF67@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158347_k127_1706872_18	367299.JOEE01000003_gene3073	1.136e-08	67.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria,4FGKC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158347_k127_1706872_2	58123.JOFJ01000004_gene1847	9.131e-127	419.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4EFIG@85012|Streptosporangiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_1706872_3	1229780.BN381_10075	6.315e-112	387.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria,3UXC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR25158347_k127_1706872_8	40571.JOEA01000032_gene706	1.92e-76	272.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria,4E0T2@85010|Pseudonocardiales	201174|Actinobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158347_k127_1706872_14	1229780.BN381_10077	1.858e-40	161.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria,3UXJ3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158347_k127_1710870_4	44060.JODL01000004_gene2671	3.825e-62	220.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158347_k127_1710870_1	83332.Rv0670	9.403e-87	298.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,234Y8@1762|Mycobacteriaceae	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158347_k127_1710870_6	1123024.AUII01000024_gene235	3.163e-49	183.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4DZP8@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158347_k127_1710870_7	1048339.KB913029_gene4118	5.669e-47	185.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4ESIT@85013|Frankiales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158347_k127_1710870_9	649747.HMPREF0083_01808	8.029e-43	173.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,26T9D@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the peptidase S11 family	dacB	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158347_k127_1710870_5	1380356.JNIK01000015_gene2651	1.173e-49	186.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4ESMT@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MerR	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158347_k127_1710870_10	351607.Acel_1227	1.65e-42	171.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4ESYX@85013|Frankiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158347_k127_1710870_12	1713.JOFV01000007_gene2927	3.766e-33	137.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4F1IX@85016|Cellulomonadaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158347_k127_1710870_0	1348662.CARG_04535	1.651e-160	533.0	COG0283@1|root,COG1160@1|root,COG0283@2|Bacteria,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,22K2N@1653|Corynebacteriaceae	201174|Actinobacteria	F	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158347_k127_1710870_2	631454.N177_1272	2.588e-85	303.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,1JN3V@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158347_k127_1710870_13	1229780.BN381_290069	2.916e-32	138.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,3UXJE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158347_k127_1710870_3	1114959.SZMC14600_14070	1.822e-68	246.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DXJJ@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158347_k127_1710870_8	1229780.BN381_290071	5.463e-43	176.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,3UWQK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158347_k127_1710870_11	446471.Xcel_1562	4.126e-37	149.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4F3CP@85017|Promicromonosporaceae	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158347_k127_175702_13	33898.JRHJ01000079_gene1420	2.769e-60	212.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158347_k127_175702_14	1223543.GP2_045_00340	3.949e-34	139.0	COG1309@1|root,COG1309@2|Bacteria,2GP91@201174|Actinobacteria,4GAVW@85026|Gordoniaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158347_k127_175702_12	649638.Trad_2970	4.61e-73	263.0	COG0534@1|root,COG0534@2|Bacteria,1WMCE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRR25158347_k127_175702_10	1313172.YM304_34110	1.746e-81	281.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_175702_0	290397.Adeh_0810	1.156e-236	767.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M5I@68525|delta/epsilon subdivisions,2WK8Y@28221|Deltaproteobacteria,2YUG8@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158347_k127_175702_6	710111.FraQA3DRAFT_1031	6.57e-112	376.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,4ETP5@85013|Frankiales	201174|Actinobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
SRR25158347_k127_175702_5	309801.trd_0604	1.2e-112	382.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158347_k127_175702_7	391037.Sare_0746	8.254e-101	339.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DBCY@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator, LacI family	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
SRR25158347_k127_175702_8	1232429.CBLL010000088_gene2487	2.881e-97	335.0	COG2182@1|root,COG2182@2|Bacteria,2HST8@201174|Actinobacteria,1W7NN@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
SRR25158347_k127_175702_4	1120960.ATXG01000001_gene840	1.768e-126	422.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4FN4U@85023|Microbacteriaceae	201174|Actinobacteria	G	N-terminal of TM subunit in PBP-dependent ABC transporters	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,TM_PBP2_N
SRR25158347_k127_175702_9	644283.Micau_0771	1.474e-87	313.0	COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,4DAZ2@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158347_k127_175702_3	219305.MCAG_03567	1.392e-164	551.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4D8KC@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158347_k127_175702_11	1341151.ASZU01000006_gene2902	2.104e-79	291.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,4HD33@91061|Bacilli,27CHM@186824|Thermoactinomycetaceae	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158347_k127_175702_1	994479.GL877878_gene2267	4.732e-171	557.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4E0K0@85010|Pseudonocardiales	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158347_k127_175702_2	28042.GU90_01475	7.322e-165	542.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4DY4S@85010|Pseudonocardiales	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158347_k127_1792006_11	1288079.AUKN01000005_gene4843	9.533e-11	63.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furA	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158347_k127_1792006_4	1381751.JAJB01000001_gene2879	2.391e-115	387.0	COG3214@1|root,COG3214@2|Bacteria,2HPNB@201174|Actinobacteria,4FB40@85019|Brevibacteriaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158347_k127_1792006_2	1122239.AULS01000011_gene21	5.625e-125	409.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1792006_10	1297742.A176_04443	1.082e-20	104.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_1792006_12	450380.JPSY01000001_gene1180	5.539e-06	52.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2,PhdYeFM_antitox
SRR25158347_k127_1792006_8	1122609.AUGT01000020_gene1045	4.58e-30	127.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1792006_7	1077972.ARGLB_039_00800	1.346e-42	171.0	COG0346@1|root,COG0346@2|Bacteria,2HTKK@201174|Actinobacteria,1WBPU@1268|Micrococcaceae	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1792006_3	1121377.KB906428_gene1172	2.153e-124	409.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158347_k127_1792006_1	1123258.AQXZ01000019_gene3303	1.615e-141	478.0	COG0491@1|root,COG0491@2|Bacteria,2GKZT@201174|Actinobacteria,4G0BG@85025|Nocardiaceae	201174|Actinobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1792006_6	1223544.GSI01S_25_00260	5.699e-63	226.0	COG4221@1|root,COG4221@2|Bacteria,2GP17@201174|Actinobacteria,4GAYS@85026|Gordoniaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1792006_5	1121930.AQXG01000016_gene1813	6.367e-71	253.0	COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,1IYJY@117747|Sphingobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158347_k127_1792006_0	656024.FsymDg_1041	1.053e-220	702.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4ES23@85013|Frankiales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158347_k127_1792006_9	1231057.AMGD01000022_gene3492	1.223e-22	107.0	COG0791@1|root,COG2247@1|root,COG0791@2|Bacteria,COG2247@2|Bacteria,1TP24@1239|Firmicutes,4HF1G@91061|Bacilli,26H21@186818|Planococcaceae	91061|Bacilli	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,NLPC_P60
SRR25158347_k127_1800446_1	744979.R2A130_1808	1.451e-45	172.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Membrane bound O-acyl transferase, MBOAT family protein	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_1800446_0	1122216.AUHW01000020_gene7	9.444e-56	221.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158347_k127_1800446_5	349521.HCH_02971	3.27e-05	56.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T42U@1236|Gammaproteobacteria,1XRWF@135619|Oceanospirillales	135619|Oceanospirillales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS
SRR25158347_k127_1800446_3	263358.VAB18032_23810	7.349e-26	117.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,4DG1X@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1800446_2	1380354.JIAN01000005_gene2567	2.485e-40	167.0	COG2606@1|root,COG2606@2|Bacteria,2IIIW@201174|Actinobacteria,4F1D0@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158347_k127_1800446_4	1380347.JNII01000006_gene1824	2.726e-23	115.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EX5G@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_1804721_4	1463854.JOHT01000003_gene6135	3.311e-07	63.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,2GYAW@201174|Actinobacteria	201174|Actinobacteria	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FctA,VWA,VWA_2
SRR25158347_k127_1804721_0	1382356.JQMP01000001_gene821	9.73e-208	675.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,27YY6@189775|Thermomicrobia	189775|Thermomicrobia	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158347_k127_1804721_3	269800.Tfu_2818	6.736e-11	65.0	COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,4EP9H@85012|Streptosporangiales	201174|Actinobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SRR25158347_k127_1804721_1	58123.JOFJ01000011_gene4736	6.272e-22	111.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2IAT1@201174|Actinobacteria,4EH1V@85012|Streptosporangiales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS
SRR25158347_k127_1804721_2	352165.HMPREF7215_2656	3.369e-12	68.0	COG0162@1|root,COG0162@2|Bacteria,3T9YV@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158347_k127_1814604_14	35754.JNYJ01000041_gene1307	2.197e-42	164.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4DGTM@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter transmembrane region	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_1814604_17	324602.Caur_3796	6.593e-28	131.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,2GBK6@200795|Chloroflexi,3770Y@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158347_k127_1814604_8	436229.JOEH01000023_gene760	8.942e-67	243.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria,2NGYG@228398|Streptacidiphilus	201174|Actinobacteria	I	Phosphate acyltransferases	plsC1	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158347_k127_1814604_13	867845.KI911784_gene3707	8.861e-44	179.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1814604_7	756067.MicvaDRAFT_2466	2.838e-69	254.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1H72B@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
SRR25158347_k127_1814604_9	1313172.YM304_36140	3.147e-66	239.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CHAT,GerE,TPR_16
SRR25158347_k127_1814604_22	263358.VAB18032_24305	0.0001175	47.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DGTB@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_1814604_5	1121372.AULK01000003_gene156	7.767e-80	272.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4FKGB@85023|Microbacteriaceae	201174|Actinobacteria	F	dCTP deaminase activity	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158347_k127_1814604_6	1123368.AUIS01000037_gene28	4.354e-72	251.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	pgmB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576	2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6	ko:K01087,ko:K01194,ko:K01838,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R02778,R11310	RC00017,RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
SRR25158347_k127_1814604_1	935839.JAGJ01000002_gene683	1.392e-269	870.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4F4N0@85017|Promicromonosporaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158347_k127_1814604_3	485913.Krac_9981	1.713e-156	513.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158347_k127_1814604_0	1229780.BN381_10327	0.0	1047.0	COG0318@1|root,COG3243@1|root,COG0318@2|Bacteria,COG3243@2|Bacteria,2GP7I@201174|Actinobacteria,3UXIR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K03821,ko:K03822	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,Abhydrolase_1,Abhydrolase_6,PHB_depo_C
SRR25158347_k127_1814604_15	1297742.A176_07468	2.622e-29	132.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,42PS5@68525|delta/epsilon subdivisions,2X77E@28221|Deltaproteobacteria,2YUM9@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158347_k127_1814604_4	983917.RGE_39620	2.469e-119	414.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2VIKV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158347_k127_1814604_21	1270193.JARP01000001_gene3013	3.658e-07	60.0	COG4251@1|root,COG4251@2|Bacteria,4NTN4@976|Bacteroidetes,1ID25@117743|Flavobacteriia,2NWZQ@237|Flavobacterium	976|Bacteroidetes	T	KaiB domain-containing protein	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
SRR25158347_k127_1814604_20	1463934.JOCF01000036_gene2348	9.101e-23	102.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158347_k127_1814604_10	1146883.BLASA_4234	1.64e-59	214.0	COG3187@1|root,COG3187@2|Bacteria,2HRWJ@201174|Actinobacteria,4EWBE@85013|Frankiales	201174|Actinobacteria	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
SRR25158347_k127_1814604_2	557599.MKAN_17350	4.536e-205	662.0	COG0247@1|root,COG3266@1|root,COG0247@2|Bacteria,COG3266@2|Bacteria,2GJ7M@201174|Actinobacteria,232WS@1762|Mycobacteriaceae	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158347_k127_1814604_11	1116369.KB890024_gene2922	1.073e-48	184.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,2VGT2@28211|Alphaproteobacteria,43RQ6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158347_k127_1814604_12	404380.Gbem_3968	3.527e-48	177.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria	1224|Proteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158347_k127_1814604_18	391037.Sare_4707	3.513e-27	117.0	COG2716@1|root,COG2716@2|Bacteria,2IGKE@201174|Actinobacteria,4DCUR@85008|Micromonosporales	201174|Actinobacteria	E	Amino acid-binding act domain protein	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
SRR25158347_k127_1814604_19	498848.TaqDRAFT_5071	4.911e-23	111.0	COG1430@1|root,COG1430@2|Bacteria,1WJRZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158347_k127_1823013_13	1123288.SOV_1c07780	1.187e-84	299.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4H6Y8@909932|Negativicutes	909932|Negativicutes	EH	Anthranilate synthase component I, N terminal region	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158347_k127_1823013_24	477974.Daud_2032	2.198e-43	179.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC4@186801|Clostridia,262GR@186807|Peptococcaceae	186801|Clostridia	EH	PFAM Aminotransferase, class IV	ilvE2	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158347_k127_1823013_22	469371.Tbis_1248	3.363e-49	184.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4E13X@85010|Pseudonocardiales	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158347_k127_1823013_16	1089544.KB912942_gene1783	3.383e-69	246.0	COG1073@1|root,COG1073@2|Bacteria,2IFI1@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_1823013_8	649831.L083_7857	1.627e-104	362.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4D9BT@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158347_k127_1823013_34	105420.BBPO01000007_gene2460	6.909e-16	90.0	COG1633@1|root,COG1633@2|Bacteria,2I2E1@201174|Actinobacteria,2NFFY@228398|Streptacidiphilus	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
SRR25158347_k127_1823013_30	1234664.AMRO01000077_gene3351	6.354e-31	133.0	COG1414@1|root,COG1414@2|Bacteria,1W784@1239|Firmicutes,4ICFU@91061|Bacilli,1WE99@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158347_k127_1823013_15	1380370.JIBA01000015_gene193	2.27e-81	279.0	COG0767@1|root,COG0767@2|Bacteria,2GXR8@201174|Actinobacteria,4FFP9@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ABC transporter	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158347_k127_1823013_14	471852.Tcur_0519	1.979e-81	281.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4EI17@85012|Streptosporangiales	201174|Actinobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158347_k127_1823013_35	479432.Sros_3023	7.347e-15	86.0	COG1463@1|root,COG1463@2|Bacteria,2I0YP@201174|Actinobacteria,4EIJA@85012|Streptosporangiales	201174|Actinobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
SRR25158347_k127_1823013_31	1380386.JIAW01000001_gene4804	8.413e-30	132.0	COG1463@1|root,COG1463@2|Bacteria,2GKHV@201174|Actinobacteria,232PS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Virulence factor Mce family protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
SRR25158347_k127_1823013_28	1429046.RR21198_3367	3.059e-33	143.0	COG1463@1|root,COG1463@2|Bacteria,2GMU6@201174|Actinobacteria,4FU6P@85025|Nocardiaceae	201174|Actinobacteria	Q	MlaD protein	mce5C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
SRR25158347_k127_1823013_27	446470.Snas_1171	1.896e-33	147.0	COG1463@1|root,COG1463@2|Bacteria,2GNXN@201174|Actinobacteria	201174|Actinobacteria	Q	Virulence factor Mce family protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
SRR25158347_k127_1823013_32	390989.JOEG01000009_gene1192	3.586e-23	116.0	COG1463@1|root,COG1463@2|Bacteria,2GJVB@201174|Actinobacteria,4DH25@85008|Micromonosporales	201174|Actinobacteria	Q	MlaD protein	mce5E	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
SRR25158347_k127_1823013_33	1223542.GM1_007_01920	4.561e-19	101.0	COG1463@1|root,COG1463@2|Bacteria,2GNEP@201174|Actinobacteria,4GAEZ@85026|Gordoniaceae	201174|Actinobacteria	Q	MlaD protein	mce5F	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
SRR25158347_k127_1823013_39	1341646.CBMO010000040_gene4660	5.481e-06	56.0	2E5H4@1|root,3308M@2|Bacteria,2IJ95@201174|Actinobacteria,239E2@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	TPR_21
SRR25158347_k127_1823013_21	1123258.AQXZ01000016_gene2370	8.611e-50	188.0	COG0589@1|root,COG0589@2|Bacteria,2IG33@201174|Actinobacteria	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158347_k127_1823013_10	471852.Tcur_4349	3.694e-97	327.0	COG1127@1|root,COG1127@2|Bacteria,2GJ1T@201174|Actinobacteria,4EHZY@85012|Streptosporangiales	201174|Actinobacteria	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158347_k127_1823013_26	1313172.YM304_40350	9.626e-37	143.0	COG0607@1|root,COG0607@2|Bacteria,2GR81@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158347_k127_1823013_18	556268.OFAG_00186	9.841e-58	207.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,4723Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158347_k127_1823013_19	479432.Sros_8959	2.289e-56	213.0	COG0500@1|root,COG2226@2|Bacteria,2IP4P@201174|Actinobacteria,4EKAN@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_1823013_5	1869.MB27_03825	3.573e-114	379.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4D9MN@85008|Micromonosporales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158347_k127_1823013_9	1123320.KB889669_gene3247	9.188e-100	338.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_1823013_3	909663.KI867150_gene1816	4.66e-153	497.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MQ47@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
SRR25158347_k127_1823013_7	469383.Cwoe_1570	2.929e-105	356.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CR0Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_1823013_25	700508.D174_13725	4.507e-41	162.0	COG0132@1|root,COG0132@2|Bacteria,2GIZ2@201174|Actinobacteria,233TF@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR25158347_k127_1823013_38	390989.JOEG01000014_gene3093	2.148e-07	59.0	2EHMB@1|root,33BD3@2|Bacteria,2HUYF@201174|Actinobacteria,4DGC3@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1823013_6	1123024.AUII01000004_gene1672	5.767e-106	355.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4DXZ3@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
SRR25158347_k127_1823013_11	1227488.C477_00105	3.59e-91	332.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,23SV0@183963|Halobacteria	183963|Halobacteria	L	exporters of the RND superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158347_k127_1823013_36	765123.HMPREF9621_01363	3.117e-10	68.0	COG1846@1|root,COG1846@2|Bacteria,2I0ED@201174|Actinobacteria,4DWEC@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158347_k127_1823013_20	1155714.KB891996_gene3683	2.183e-52	202.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1823013_4	298654.FraEuI1c_6257	4.111e-139	454.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4ERDE@85013|Frankiales	201174|Actinobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158347_k127_1823013_1	526225.Gobs_4538	1.24e-271	849.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4ERWB@85013|Frankiales	201174|Actinobacteria	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158347_k127_1823013_29	1313172.YM304_31100	6.255e-33	141.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158347_k127_1823013_12	1304865.JAGF01000001_gene703	5.296e-89	309.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	txlA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,SfLAP,Thioredoxin
SRR25158347_k127_1823013_0	43989.cce_4353	0.0	1225.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,3KFR5@43988|Cyanothece	1117|Cyanobacteria	C	glutamate synthase alpha subunit domain protein	glsF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158347_k127_1823013_2	450851.PHZ_c0252	1.313e-185	597.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2KEZN@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_1823013_17	1122134.KB893650_gene220	8.772e-60	216.0	2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1944747_1	1869.MB27_33840	1.956e-31	131.0	COG4974@1|root,COG4974@2|Bacteria,2GNXS@201174|Actinobacteria,4D9Z6@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_1944747_0	1120950.KB892740_gene2536	1.469e-36	155.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria,4DN49@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158347_k127_1946519_3	413816.BBJP01000013_gene1015	2.035e-86	292.0	COG0437@1|root,arCOG06257@1|root,arCOG01500@2157|Archaea,arCOG06257@2157|Archaea,2XTS6@28890|Euryarchaeota,23U4H@183963|Halobacteria	183963|Halobacteria	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_10,Fer4_11,Fer4_7,Ferredoxin_N
SRR25158347_k127_1946519_1	1293047.CBMA010000008_gene309	1.099e-133	440.0	COG5557@1|root,arCOG02025@2157|Archaea,2XTP4@28890|Euryarchaeota,23UCD@183963|Halobacteria	183963|Halobacteria	C	Polysulphide reductase	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SRR25158347_k127_1946519_9	797303.Natpe_2385	2.63e-06	59.0	arCOG10320@1|root,arCOG10320@2157|Archaea,2XYYB@28890|Euryarchaeota,23WXZ@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1946519_4	1382306.JNIM01000001_gene1112	2.88e-71	247.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_1946519_5	1304865.JAGF01000001_gene1114	6.548e-57	224.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_1946519_6	1245469.S58_61980	4.48e-50	194.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,1RGKE@1224|Proteobacteria,2TVMC@28211|Alphaproteobacteria,3JRR5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HWE_HK,HisKA,PAS_4,PAS_8,PAS_9
SRR25158347_k127_1946519_2	1273125.Rrhod_2526	1.02e-110	370.0	2CGV9@1|root,333YX@2|Bacteria,2IE67@201174|Actinobacteria	201174|Actinobacteria	S	Capsule biosynthesis CapC	-	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
SRR25158347_k127_1946519_0	1386089.N865_17475	2.032e-191	609.0	COG0285@1|root,COG0285@2|Bacteria,2GKSV@201174|Actinobacteria,4FI9Q@85021|Intrasporangiaceae	201174|Actinobacteria	H	Mur ligase middle domain	capB	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_M
SRR25158347_k127_1946519_7	1273125.Rrhod_2528	3.371e-35	146.0	2BACR@1|root,323T5@2|Bacteria,2H8I7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1946519_8	1128421.JAGA01000003_gene2948	1.947e-10	72.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158347_k127_195586_13	146922.JOFU01000057_gene806	2.05e-41	158.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158347_k127_195586_6	1211815.CBYP010000016_gene2612	7.885e-143	460.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4EUUB@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_195586_0	58123.JOFJ01000006_gene101	1.531e-218	708.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EFXA@85012|Streptosporangiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_195586_12	47716.JOFH01000048_gene4255	6.276e-53	194.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158347_k127_195586_3	1089545.KB913037_gene2621	1.838e-184	592.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,4E0V7@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD19	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_195586_10	685727.REQ_43540	4.871e-81	283.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,4FXAS@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_195586_5	479433.Caci_2176	1.056e-166	533.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE26	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_195586_11	208444.JNYY01000008_gene8571	4.023e-79	271.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DYN3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158347_k127_195586_4	1394178.AWOO02000005_gene3693	1.304e-169	543.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,4EHB7@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158347_k127_195586_7	1155718.KB891896_gene2268	8.895e-115	384.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158347_k127_195586_9	1160718.SU9_28446	7.791e-99	332.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158347_k127_195586_2	1463917.JODC01000001_gene327	3.006e-185	593.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_195586_15	1229780.BN381_40057	1.524e-35	144.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158347_k127_195586_16	388401.RB2150_11636	8.606e-27	115.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158347_k127_195586_8	479433.Caci_3088	2.814e-108	362.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria	201174|Actinobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158347_k127_195586_1	1123320.KB889730_gene5893	1.499e-186	595.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
SRR25158347_k127_195586_14	1240349.ANGC01000004_gene1819	6.601e-37	144.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria,4G0Q2@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_1985177_6	1177594.MIC448_350027	0.0007427	42.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_1985177_3	1313172.YM304_13740	1.015e-22	100.0	2DR8X@1|root,33AQM@2|Bacteria,2GXTC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1985177_2	1048339.KB913029_gene16	1.549e-24	121.0	COG0823@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2931@2|Bacteria,2I7DQ@201174|Actinobacteria,4EXHP@85013|Frankiales	2|Bacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	lktA	-	-	ko:K03641,ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11,2.C.1.2	-	-	HemolysinCabind,PA,PD40,PDZ_2,Peptidase_M28,RTX,RTX_C
SRR25158347_k127_1985177_5	292459.STH2021	4.288e-16	93.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
SRR25158347_k127_1985177_4	1306174.JODP01000011_gene6700	2.299e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,2GTC7@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_1985177_1	1183438.GKIL_3602	5.205e-28	117.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158347_k127_20022_10	1122185.N792_12245	1.03e-10	75.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_20022_2	1907.SGLAU_10950	2.456e-94	316.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_20022_5	671143.DAMO_2352	4.206e-67	238.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
SRR25158347_k127_20022_9	1120797.KB908276_gene2705	3.664e-15	86.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,23DF0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158347_k127_20022_1	391037.Sare_2139	3.742e-149	487.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DEDW@85008|Micromonosporales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158347_k127_20022_0	391625.PPSIR1_40550	4.371e-236	756.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WJ61@28221|Deltaproteobacteria,2YZ97@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_20022_4	196162.Noca_0256	7.846e-71	261.0	COG1073@1|root,COG1073@2|Bacteria,2IBGB@201174|Actinobacteria,4DPXH@85009|Propionibacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_20022_8	1177594.MIC448_2190012	4.731e-35	149.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_20022_6	1074488.AGBX01000007_gene1964	3.643e-52	202.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4FC9Y@85020|Dermabacteraceae	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158347_k127_20022_3	1463856.JOHY01000070_gene3572	1.41e-71	263.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158347_k127_20022_7	1385519.N801_06920	4.374e-48	194.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4FFV2@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158347_k127_20112_34	204669.Acid345_1338	1.035e-71	256.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria,2JHRI@204432|Acidobacteriia	204432|Acidobacteriia	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158347_k127_20112_30	1463854.JOHT01000025_gene1260	2.931e-81	281.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158347_k127_20112_59	266940.Krad_1868	2.285e-34	152.0	COG0845@1|root,COG0845@2|Bacteria,2I8EY@201174|Actinobacteria	201174|Actinobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158347_k127_20112_32	860228.Ccan_09160	2.7e-79	277.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,1EQ2V@1016|Capnocytophaga	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_20112_12	134676.ACPL_5130	6.306e-123	410.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DBFV@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_20112_62	298653.Franean1_0563	2.158e-32	129.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4EVQI@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158347_k127_20112_53	2045.KR76_18835	9.58e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4DR2G@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_20112_11	479435.Kfla_6393	2.594e-124	410.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4DN6Q@85009|Propionibacteriales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158347_k127_20112_18	106370.Francci3_0479	2.413e-110	369.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4ERGC@85013|Frankiales	201174|Actinobacteria	M	PFAM NAD-dependent epimerase dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
SRR25158347_k127_20112_22	40571.JOEA01000011_gene2397	1.776e-102	348.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,4E0YI@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158347_k127_20112_74	263358.VAB18032_01795	8.08e-16	90.0	COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria,4DC1I@85008|Micromonosporales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_20112_50	471852.Tcur_4444	2.786e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4EIG3@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_20112_56	1089455.MOPEL_074_00340	5.238e-39	156.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4F6J9@85018|Dermatophilaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158347_k127_20112_67	351607.Acel_1209	5.321e-25	119.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158347_k127_20112_15	1193181.BN10_140037	4.941e-119	400.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FE5K@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_20112_80	926569.ANT_02430	2.858e-05	55.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_20112_78	1169144.KB910948_gene3601	2.728e-07	63.0	COG0695@1|root,COG0695@2|Bacteria,1VHHY@1239|Firmicutes,4HQ4Z@91061|Bacilli,1ZIXQ@1386|Bacillus	91061|Bacilli	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158347_k127_20112_39	749414.SBI_06009	6.346e-65	231.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158347_k127_20112_29	196162.Noca_0494	1.289e-84	295.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4DPDT@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158347_k127_20112_42	356851.JOAN01000015_gene2739	5.93e-64	230.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4D9YK@85008|Micromonosporales	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
SRR25158347_k127_20112_57	1246474.ANBE01000022_gene3901	3.673e-36	154.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4EFW8@85012|Streptosporangiales	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158347_k127_20112_76	350054.Mflv_3865	1.514e-10	73.0	COG1295@1|root,COG1295@2|Bacteria,2HR7G@201174|Actinobacteria,236PB@1762|Mycobacteriaceae	201174|Actinobacteria	S	PFAM ribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR25158347_k127_20112_16	1237500.ANBA01000006_gene2552	2.038e-116	384.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4EHK2@85012|Streptosporangiales	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158347_k127_20112_51	1120934.KB894414_gene3820	3.527e-44	173.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
SRR25158347_k127_20112_41	2074.JNYD01000004_gene4906	2.888e-64	235.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
SRR25158347_k127_20112_9	266117.Rxyl_1975	1.22e-131	438.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CPG9@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_20112_68	1033730.CAHG01000008_gene3007	2.279e-23	116.0	COG0526@1|root,COG0526@2|Bacteria,2IMNX@201174|Actinobacteria,4DRHV@85009|Propionibacteriales	201174|Actinobacteria	CO	Redoxin	resA_1	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158347_k127_20112_70	1229780.BN381_450012	6.257e-23	102.0	COG1143@1|root,COG1143@2|Bacteria,2H4NQ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
SRR25158347_k127_20112_13	1313172.YM304_04010	6.458e-122	395.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158347_k127_20112_44	1313172.YM304_04020	8.067e-60	216.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158347_k127_20112_54	1229780.BN381_450009	1.192e-41	161.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158347_k127_20112_69	1229780.BN381_450008	3.829e-23	111.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158347_k127_20112_77	717605.Theco_2847	2.377e-07	62.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,26ZR6@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccB	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SRR25158347_k127_20112_63	58123.JOFJ01000002_gene2615	2.439e-32	139.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4EJ9T@85012|Streptosporangiales	201174|Actinobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158347_k127_20112_47	1283287.KB822575_gene444	2.006e-55	208.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4DPTU@85009|Propionibacteriales	201174|Actinobacteria	O	cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158347_k127_20112_38	926564.KI911686_gene5494	1.101e-65	246.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4F3QQ@85017|Promicromonosporaceae	201174|Actinobacteria	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158347_k127_20112_48	365528.KB891252_gene5666	9.204e-50	203.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4ESE9@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158347_k127_20112_52	67275.JOAP01000051_gene956	6.819e-44	169.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158347_k127_20112_37	1048339.KB913029_gene4121	4.099e-67	235.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4ESQB@85013|Frankiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158347_k127_20112_75	1123073.KB899241_gene1989	1.093e-14	80.0	COG3794@1|root,COG3794@2|Bacteria,1QS6V@1224|Proteobacteria,1RVIU@1236|Gammaproteobacteria,1XBHU@135614|Xanthomonadales	135614|Xanthomonadales	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158347_k127_20112_17	471853.Bcav_3431	1.172e-114	383.0	28HWT@1|root,2Z82P@2|Bacteria,2IJH8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_20112_26	1236902.ANAS01000001_gene1830	1.324e-87	303.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4EIDY@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_20112_2	1120950.KB892777_gene766	9.188e-169	556.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4DNED@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_20112_36	309801.trd_A0305	4.679e-68	244.0	COG1575@1|root,COG1575@2|Bacteria,2G5ZC@200795|Chloroflexi,27XVA@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158347_k127_20112_20	28444.JODQ01000006_gene649	6.605e-108	369.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4EH71@85012|Streptosporangiales	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158347_k127_20112_6	469371.Tbis_1708	8.212e-148	496.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4DYET@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158347_k127_20112_19	2002.JOEQ01000015_gene5006	9.627e-110	374.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4EH22@85012|Streptosporangiales	201174|Actinobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158347_k127_20112_79	1429046.RR21198_3539	1.164e-05	54.0	COG0789@1|root,COG0789@2|Bacteria,2IFX0@201174|Actinobacteria,4G3CP@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158347_k127_20112_40	1380356.JNIK01000018_gene712	2.598e-64	230.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4ERZ2@85013|Frankiales	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158347_k127_20112_10	298654.FraEuI1c_6275	8.314e-128	432.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4ERPF@85013|Frankiales	201174|Actinobacteria	C	geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR25158347_k127_20112_72	935866.JAER01000013_gene1139	1.626e-21	99.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4DR0D@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158347_k127_20112_31	675635.Psed_5568	2.957e-81	283.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4DYGD@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158347_k127_20112_55	351607.Acel_0269	1.367e-40	158.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4ESFW@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158347_k127_20112_1	446470.Snas_1277	1.252e-179	578.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4EYAM@85014|Glycomycetales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158347_k127_20112_49	106370.Francci3_0542	1.746e-47	186.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4ESCP@85013|Frankiales	201174|Actinobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158347_k127_20112_4	35754.JNYJ01000036_gene3786	1.137e-161	523.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4DAYA@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158347_k127_20112_0	33898.JRHJ01000054_gene5991	2.83e-212	687.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria	201174|Actinobacteria	C	NADH-quinone oxidoreductase	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158347_k127_20112_21	1121877.JQKF01000009_gene576	1.192e-103	353.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CMTV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158347_k127_20112_43	1894.JOER01000013_gene1162	3.218e-63	224.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158347_k127_20112_71	710111.FraQA3DRAFT_3914	7.9e-22	108.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4ESIY@85013|Frankiales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158347_k127_20112_66	211114.JOEF01000002_gene4194	2.365e-26	110.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4E4HB@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158347_k127_20112_3	929556.Solca_3729	1.167e-163	536.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_20112_5	269799.Gmet_3343	1.967e-151	494.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158347_k127_20112_25	656024.FsymDg_3994	5.905e-95	332.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4ERCH@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158347_k127_20112_27	106370.Francci3_0552	3.92e-87	320.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4ERU8@85013|Frankiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158347_k127_20112_46	502025.Hoch_0349	3.559e-56	209.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.11,5.4.2.12	ko:K01834,ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158347_k127_20112_73	1075090.GOAMR_06_00160	2.893e-20	106.0	COG0683@1|root,COG0683@2|Bacteria,2HN3Z@201174|Actinobacteria,4GGS7@85026|Gordoniaceae	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_20112_61	1048339.KB913029_gene2400	1.815e-32	147.0	COG0559@1|root,COG0559@2|Bacteria,2GJM0@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_20112_65	331869.BAL199_06024	9.292e-27	127.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT64@28211|Alphaproteobacteria,4BRIT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	MA20_22605	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_20112_45	1121926.AXWO01000003_gene650	1.071e-58	228.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4EXRT@85014|Glycomycetales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_20112_35	319795.Dgeo_1209	9.669e-71	247.0	COG0410@1|root,COG0410@2|Bacteria,1WJM5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158347_k127_20112_23	1435356.Y013_00880	4.008e-101	342.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4FXPC@85025|Nocardiaceae	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158347_k127_20112_28	253839.SSNG_04166	1.932e-85	287.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158347_k127_20112_60	219305.MCAG_02147	5.605e-34	144.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria,4DBTZ@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158347_k127_20112_7	479435.Kfla_6453	2.495e-140	460.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DSY9@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the complex I 49 kDa subunit family	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158347_k127_20112_24	28444.JODQ01000018_gene7265	5.831e-98	332.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria,4EHPA@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158347_k127_20112_33	469371.Tbis_0320	1.328e-73	274.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,4E32N@85010|Pseudonocardiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158347_k127_20112_58	1394178.AWOO02000003_gene2830	7.317e-35	152.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria,4EIJM@85012|Streptosporangiales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158347_k127_20112_64	118173.KB235914_gene2226	1.605e-28	119.0	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria,1HBH9@1150|Oscillatoriales	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
SRR25158347_k127_20112_14	305700.B447_03663	1.545e-120	415.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales	206389|Rhodocyclales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_20112_8	479432.Sros_0673	2.039e-136	447.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4EI1F@85012|Streptosporangiales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158347_k127_203074_2	760142.Hipma_0539	1.279e-20	107.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,42PVB@68525|delta/epsilon subdivisions,2WIMK@28221|Deltaproteobacteria,2M72Q@213113|Desulfurellales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158347_k127_203074_0	1206732.BAGD01000272_gene6054	8.475e-76	265.0	COG0637@1|root,COG1554@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,COG1877@2|Bacteria,2GKEV@201174|Actinobacteria,4FU49@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	otsB1	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	3.1.3.12,3.2.1.28	ko:K01087,ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010,R02778	RC00017,RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
SRR25158347_k127_203074_3	1313172.YM304_38910	7.768e-19	91.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_203074_1	543632.JOJL01000005_gene4760	2.208e-60	222.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRR25158347_k127_204072_7	512565.AMIS_53750	3.517e-66	238.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4D8TF@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_204072_4	105422.BBPM01000026_gene4078	1.094e-99	334.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,2NGR6@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_204072_5	1122182.KB903838_gene4198	8.732e-92	319.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
SRR25158347_k127_204072_3	1906.SFRA_18070	2.015e-105	347.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_204072_10	55952.BU52_09685	4.254e-44	173.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158347_k127_204072_9	1229780.BN381_170002	1.412e-62	228.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,3UWCF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158347_k127_204072_0	1121877.JQKF01000003_gene1555	3.075e-140	458.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158347_k127_204072_8	106370.Francci3_1507	3.893e-64	226.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158347_k127_204072_12	1120959.ATXF01000009_gene730	1.149e-22	102.0	COG4747@1|root,COG4747@2|Bacteria,2HTE7@201174|Actinobacteria,4FT5U@85023|Microbacteriaceae	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_204072_1	1229203.KI301992_gene1693	1.941e-118	388.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,3UX4X@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Zinc-binding dehydrogenase	yogA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_204072_14	266117.Rxyl_0591	3.768e-06	55.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158347_k127_204072_6	1160137.KB907307_gene3005	9.109e-69	248.0	COG1819@1|root,COG1819@2|Bacteria,2I8EN@201174|Actinobacteria,4FWJ2@85025|Nocardiaceae	201174|Actinobacteria	CG	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158347_k127_204072_13	675635.Psed_1157	7.161e-14	76.0	COG2146@1|root,COG2146@2|Bacteria,2IQN9@201174|Actinobacteria,4EF04@85010|Pseudonocardiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158347_k127_204072_15	66875.JODY01000008_gene2351	0.0006143	51.0	COG3415@1|root,COG3415@2|Bacteria,2HK0D@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Terminase_5
SRR25158347_k127_204072_2	298655.KI912266_gene5297	6.865e-113	378.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_204072_11	1150864.MILUP08_42223	3.825e-42	173.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158347_k127_2044458_9	523841.HFX_0970	1.463e-24	112.0	arCOG14225@1|root,arCOG14225@2157|Archaea,2XYCA@28890|Euryarchaeota,23W9H@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2044458_4	479432.Sros_6721	6.662e-129	420.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4EFXF@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158347_k127_2044458_6	1463879.JOHP01000017_gene2404	7.306e-94	338.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158347_k127_2044458_2	264732.Moth_1809	4.277e-196	629.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
SRR25158347_k127_2044458_0	471852.Tcur_1775	0.0	1049.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4EFWY@85012|Streptosporangiales	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158347_k127_2044458_1	1266914.ATUK01000010_gene1266	2.129e-217	711.0	COG3280@1|root,COG3280@2|Bacteria	2|Bacteria	G	synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
SRR25158347_k127_2044458_3	1048339.KB913029_gene1111	3.464e-140	466.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4ERC9@85013|Frankiales	201174|Actinobacteria	G	PFAM glycoside hydrolase family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158347_k127_2044458_8	996637.SGM_2780	1.449e-55	202.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158347_k127_2044458_7	1463921.JODF01000015_gene7057	1.724e-87	318.0	COG4191@1|root,COG4191@2|Bacteria,2I3H5@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_2044458_5	512565.AMIS_40330	3.084e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,2GMVN@201174|Actinobacteria,4D8W6@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2044458_11	318829.MGG_14917T0	6.321e-05	55.0	KOG4441@1|root,KOG4441@2759|Eukaryota,38N9Z@33154|Opisthokonta	33154|Opisthokonta	T	Kelch-like family member 25	KLHL25	GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0006446,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016567,GO:0019222,GO:0019538,GO:0019941,GO:0030163,GO:0031323,GO:0031326,GO:0031461,GO:0031463,GO:0032268,GO:0032446,GO:0032991,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051603,GO:0060255,GO:0065007,GO:0070647,GO:0071704,GO:0080090,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234,GO:2000112	-	ko:K10462	-	-	-	-	ko00000,ko04121	-	-	-	BACK,BTB,Kelch_1
SRR25158347_k127_2044458_10	1380346.JNIH01000067_gene4467	3.95e-15	83.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_2078165_9	1246474.ANBE01000035_gene2581	2.494e-06	52.0	29XFI@1|root,30J5Y@2|Bacteria,2GVKZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2078165_3	1120941.AUBL01000004_gene1755	6.331e-55	202.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4D3X5@85005|Actinomycetales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158347_k127_2078165_5	1121360.AUAQ01000015_gene1896	1.912e-21	97.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,22NUS@1653|Corynebacteriaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158347_k127_2078165_7	1343740.M271_17090	2.323e-17	91.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158347_k127_2078165_4	1229780.BN381_10046	5.145e-29	123.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,3UWWW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRR25158347_k127_2078165_1	351607.Acel_0651	3.4e-212	677.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4ERF0@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158347_k127_2078165_2	512565.AMIS_71930	1.03e-78	272.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4D8FX@85008|Micromonosporales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158347_k127_2078165_0	1504319.GM45_6105	4.557e-213	672.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,3UW86@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158347_k127_2078165_6	591157.SSLG_04718	6.643e-21	98.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158347_k127_2078165_8	1206735.BAGG01000057_gene2322	1.405e-07	64.0	COG5650@1|root,COG5650@2|Bacteria,2GN1J@201174|Actinobacteria,4FZPB@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158347_k127_2085730_2	1380393.JHVP01000010_gene2908	3.758e-89	306.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4ESQS@85013|Frankiales	201174|Actinobacteria	S	beta-lactamase domain protein	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158347_k127_2085730_4	1415780.JPOG01000001_gene2803	4.261e-76	271.0	COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,1S9T2@1236|Gammaproteobacteria,1X8H7@135614|Xanthomonadales	135614|Xanthomonadales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2085730_9	525904.Tter_1742	5.367e-08	66.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_2085730_3	383372.Rcas_3059	2.619e-84	300.0	COG1131@1|root,COG1131@2|Bacteria,2GAQH@200795|Chloroflexi,3753M@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_2085730_8	97138.C820_01574	9.091e-18	97.0	COG1668@1|root,COG1668@2|Bacteria,1UIA3@1239|Firmicutes,25EF1@186801|Clostridia,36UNK@31979|Clostridiaceae	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158347_k127_2085730_7	867845.KI911784_gene3519	3.999e-22	112.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2085730_1	324602.Caur_3412	3.074e-102	349.0	COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_2085730_6	595460.RRSWK_06298	4.013e-36	149.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158347_k127_2085730_5	1229780.BN381_350143	4.128e-45	187.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
SRR25158347_k127_2085730_0	1128421.JAGA01000003_gene3234	7.699e-130	445.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
SRR25158347_k127_2091808_24	414996.IL38_16835	9.133e-47	175.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2I28C@201174|Actinobacteria,407UH@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_1
SRR25158347_k127_2091808_25	994573.T472_0210545	1.174e-43	172.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,36W8R@31979|Clostridiaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR25158347_k127_2091808_14	1120942.AUBM01000004_gene1771	1.385e-80	284.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4D3DP@85005|Actinomycetales	201174|Actinobacteria	GM	ABC transporter, ATP-binding protein	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158347_k127_2091808_22	717605.Theco_3901	2.409e-48	186.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,4HQF6@91061|Bacilli,26THF@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_2091808_32	1348663.KCH_28740	1.508e-22	104.0	COG0346@1|root,COG0346@2|Bacteria,2HP3N@201174|Actinobacteria,2M5WZ@2063|Kitasatospora	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_2091808_42	1128421.JAGA01000002_gene219	8.19e-08	64.0	COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR25158347_k127_2091808_9	44060.JODL01000019_gene4749	4.431e-108	381.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158347_k127_2091808_11	452652.KSE_29430	1.971e-97	327.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,2M0AK@2063|Kitasatospora	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158347_k127_2091808_1	471852.Tcur_4075	1.19e-309	971.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4EG69@85012|Streptosporangiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	fbiC	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158347_k127_2091808_21	1246448.ANAZ01000043_gene1274	2.242e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4EIS2@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158347_k127_2091808_28	1077144.AGFF01000024_gene378	2.111e-32	130.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158347_k127_2091808_15	1288079.AUKN01000008_gene5810	1.401e-78	296.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158347_k127_2091808_44	1116232.AHBF01000025_gene6921	0.0001373	55.0	COG3147@1|root,COG3147@2|Bacteria,2HC8A@201174|Actinobacteria	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2091808_47	100226.SCO3032	0.0004164	53.0	COG3147@1|root,COG3147@2|Bacteria,2HC8A@201174|Actinobacteria	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2091808_30	266940.Krad_4165	7.258e-30	125.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158347_k127_2091808_38	1285583.CCASEI_10820	3.156e-10	68.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,22NKM@1653|Corynebacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
SRR25158347_k127_2091808_36	485913.Krac_10483	1.273e-11	70.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
SRR25158347_k127_2091808_2	365528.KB891159_gene5428	8.399e-161	518.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4ERK1@85013|Frankiales	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158347_k127_2091808_37	338963.Pcar_1262	7.634e-11	64.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,43STJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158347_k127_2091808_23	1121468.AUBR01000012_gene2574	3.41e-47	186.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRR25158347_k127_2091808_19	861299.J421_3835	3.404e-61	224.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158347_k127_2091808_34	1234595.C725_2115	1.899e-12	78.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,4BQIJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158347_k127_2091808_41	469378.Ccur_13290	6.166e-08	63.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CVME@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158347_k127_2091808_12	471852.Tcur_4038	2.546e-93	311.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158347_k127_2091808_31	1075090.GOAMR_20_02590	3.971e-27	120.0	COG0454@1|root,COG0456@2|Bacteria,2I2E3@201174|Actinobacteria,4GF4K@85026|Gordoniaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_2091808_0	471852.Tcur_4035	0.0	1045.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4EGCZ@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158347_k127_2091808_20	561175.KB894104_gene1226	6.138e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4EHPQ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_2091808_39	446471.Xcel_2491	7.546e-10	63.0	COG5662@1|root,COG5662@2|Bacteria,2I0MN@201174|Actinobacteria,4F4TV@85017|Promicromonosporaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158347_k127_2091808_13	1077144.AGFF01000007_gene1799	3.359e-93	317.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158347_k127_2091808_26	649831.L083_5933	3.077e-40	155.0	COG1426@1|root,COG1426@2|Bacteria,2I2W5@201174|Actinobacteria,4DCQD@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158347_k127_2091808_45	1231241.Mc24_08149	0.0002437	51.0	2C0MY@1|root,2ZC2Z@2|Bacteria,2GD2U@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2091808_18	351607.Acel_0546	7.455e-63	234.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4ETB2@85013|Frankiales	201174|Actinobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158347_k127_2091808_40	1184607.AUCHE_08_05730	9.727e-09	68.0	COG2206@1|root,COG2206@2|Bacteria,2GJB1@201174|Actinobacteria,4F70R@85018|Dermatophilaceae	201174|Actinobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158347_k127_2091808_35	867903.ThesuDRAFT_02369	3.681e-12	76.0	29Y0M@1|root,30JTI@2|Bacteria,1VEVD@1239|Firmicutes,24QVV@186801|Clostridia,3WDJ2@538999|Clostridiales incertae sedis	186801|Clostridia	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158347_k127_2091808_16	378806.STAUR_3464	2.121e-71	250.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,42RTA@68525|delta/epsilon subdivisions,2WNCA@28221|Deltaproteobacteria,2YV29@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_2091808_43	382464.ABSI01000005_gene1242	2.464e-05	52.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,2ITQW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_2091808_6	2002.JOEQ01000048_gene7423	3.049e-134	442.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4EG9F@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR25158347_k127_2091808_29	478801.Ksed_08790	3.042e-32	127.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,1ZW4B@145357|Dermacoccaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158347_k127_2091808_17	1123320.KB889737_gene5367	2.194e-63	232.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158347_k127_2091808_8	266117.Rxyl_2308	7.008e-113	391.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_2091808_5	479434.Sthe_2023	2.834e-152	492.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158347_k127_2091808_3	1463864.JOGO01000002_gene2113	1.061e-160	521.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2GIXE@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158347_k127_2091808_27	471852.Tcur_3942	2.815e-33	132.0	COG0745@1|root,COG0745@2|Bacteria,2I2Z1@201174|Actinobacteria,4EJHI@85012|Streptosporangiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_2091808_4	1380356.JNIK01000016_gene3682	2.121e-155	507.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4ERR2@85013|Frankiales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158347_k127_2091808_7	1996.JOFO01000002_gene5621	3.341e-132	438.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4EH7X@85012|Streptosporangiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158347_k127_2091808_10	1502724.FF80_00016	6.312e-100	336.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U2WH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	proteins, homologs of microcin C7 resistance protein MccF	mccF	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158347_k127_2091808_33	298655.KI912266_gene21	2.454e-13	82.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158347_k127_2121464_3	345341.KUTG_02357	2.762e-32	140.0	COG2856@1|root,COG2856@2|Bacteria,2IFJ3@201174|Actinobacteria,4E2VC@85010|Pseudonocardiales	201174|Actinobacteria	K	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_31,Peptidase_M78
SRR25158347_k127_2121464_8	298655.KI912266_gene5804	2.636e-07	62.0	2CACX@1|root,33W9V@2|Bacteria,2IABD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2121464_1	1156844.KB891799_gene1235	1.507e-57	218.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,TIG
SRR25158347_k127_2121464_2	644283.Micau_0029	1.141e-35	143.0	2DNAB@1|root,32WEV@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
SRR25158347_k127_2121464_0	478741.JAFS01000002_gene991	3.493e-121	407.0	COG3465@1|root,COG3465@2|Bacteria	2|Bacteria	-	-	-	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427,ko:K09388	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Macro,Methylase_S
SRR25158347_k127_2121464_5	875328.JDM601_1240	6.258e-20	92.0	29120@1|root,2ZNPJ@2|Bacteria,2HC2Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2121464_7	1449976.KALB_6085	9.335e-13	80.0	COG2508@1|root,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria,4DZNP@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158347_k127_2190301_18	1128421.JAGA01000002_gene219	1.383e-07	62.0	COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR25158347_k127_2190301_1	1229780.BN381_80377	1.529e-126	429.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158347_k127_2190301_6	298653.Franean1_6564	2.292e-93	332.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4ERVT@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158347_k127_2190301_5	408672.NBCG_00943	1.956e-96	318.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4DP0B@85009|Propionibacteriales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158347_k127_2190301_0	298654.FraEuI1c_6876	1.232e-164	527.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4ERII@85013|Frankiales	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158347_k127_2190301_4	543632.JOJL01000050_gene7370	5.42e-106	355.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4DB2H@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
SRR25158347_k127_2190301_2	1283299.AUKG01000001_gene2532	6.738e-120	407.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CR5S@84995|Rubrobacteria	84995|Rubrobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158347_k127_2190301_13	314230.DSM3645_19016	2.378e-25	108.0	COG1694@1|root,COG1694@2|Bacteria,2J047@203682|Planctomycetes	203682|Planctomycetes	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158347_k127_2190301_11	1382306.JNIM01000001_gene1890	2.213e-43	172.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158347_k127_2190301_19	1296416.JACB01000063_gene2002	0.0008164	48.0	2DQVQ@1|root,338YQ@2|Bacteria,4NWGI@976|Bacteroidetes,1IIE8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2190301_8	446470.Snas_0594	1.298e-67	240.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4EXPT@85014|Glycomycetales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158347_k127_2190301_3	446468.Ndas_5307	5.897e-111	392.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4EHEN@85012|Streptosporangiales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158347_k127_2190301_15	298654.FraEuI1c_5836	8.47e-17	84.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4ET3Z@85013|Frankiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whmD	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158347_k127_2190301_17	313612.L8106_17009	9.628e-08	63.0	2DBZS@1|root,2ZC3A@2|Bacteria,1G58M@1117|Cyanobacteria,1HARD@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158347_k127_2190301_7	477641.MODMU_0594	1.555e-86	313.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4ERU9@85013|Frankiales	201174|Actinobacteria	D	PFAM Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158347_k127_2190301_9	469371.Tbis_0198	1.133e-56	225.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4DYGT@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158347_k127_2190301_12	309801.trd_1267	4.347e-38	166.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158347_k127_2190301_14	1123320.KB889562_gene6894	1.032e-18	91.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158347_k127_2190301_16	1206730.BAGA01000006_gene5259	7.907e-13	70.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4G3YM@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158347_k127_2190301_10	548476.cauri_0203	1.478e-49	183.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,22N64@1653|Corynebacteriaceae	201174|Actinobacteria	J	translation initiation inhibitor, yjgF family	yabJ	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158347_k127_2194164_28	369723.Strop_0822	1.185e-22	111.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria,4DAZ1@85008|Micromonosporales	201174|Actinobacteria	CO	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_2194164_9	644283.Micau_0798	8.738e-94	333.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4DA0K@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K06148,ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_2194164_4	1123322.KB904669_gene3540	8.482e-120	402.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria	201174|Actinobacteria	C	cytochrome D ubiquinol oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158347_k127_2194164_2	479432.Sros_4548	9.128e-185	591.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4EGAA@85012|Streptosporangiales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158347_k127_2194164_22	443906.CMM_0308	3.594e-44	176.0	COG1474@1|root,COG1474@2|Bacteria,2IAJU@201174|Actinobacteria,4FN6P@85023|Microbacteriaceae	201174|Actinobacteria	LO	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158347_k127_2194164_27	1122604.JONR01000025_gene4538	5.265e-23	117.0	COG0613@1|root,COG1409@1|root,COG3266@1|root,COG0613@2|Bacteria,COG1409@2|Bacteria,COG3266@2|Bacteria,1R8EE@1224|Proteobacteria,1RZPP@1236|Gammaproteobacteria,1X5WA@135614|Xanthomonadales	135614|Xanthomonadales	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2194164_14	106370.Francci3_2511	9.309e-75	271.0	COG2132@1|root,COG2132@2|Bacteria,2GPUP@201174|Actinobacteria,4ES9Q@85013|Frankiales	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158347_k127_2194164_8	1229780.BN381_80366	1.546e-97	350.0	COG4677@1|root,COG4677@2|Bacteria,2I7VB@201174|Actinobacteria	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158347_k127_2194164_25	926550.CLDAP_15510	1.151e-35	145.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158347_k127_2194164_5	1463895.JODA01000009_gene3574	1.13e-118	392.0	COG4143@1|root,COG4143@2|Bacteria,2GMWD@201174|Actinobacteria	201174|Actinobacteria	H	ABC transporter, periplasmic binding protein, thiB subfamily	thiB	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
SRR25158347_k127_2194164_3	1463858.JOHR01000017_gene4601	1.475e-173	561.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	thiP	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1
SRR25158347_k127_2194164_15	1449355.JQNR01000005_gene4658	5.373e-68	259.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	fbpC	-	-	ko:K02052,ko:K02062	ko02010,ko02024,map02010,map02024	M00191,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.19	-	-	ABC_tran,TOBE_2
SRR25158347_k127_2194164_33	1120956.JHZK01000017_gene2676	1.477e-06	56.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,1JNSV@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	petR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2194164_32	929712.KI912613_gene289	4.61e-16	84.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	COXG,Polyketide_cyc2
SRR25158347_k127_2194164_0	1168065.DOK_00445	2.512e-270	859.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria,1J99J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2366 Protein related to penicillin acylase	pvdQ	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
SRR25158347_k127_2194164_13	164757.Mjls_2757	1.298e-79	273.0	COG2186@1|root,COG2186@2|Bacteria,2I90D@201174|Actinobacteria,236Z8@1762|Mycobacteriaceae	201174|Actinobacteria	K	GntR family	mce2R	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158347_k127_2194164_12	882083.SacmaDRAFT_2548	9.938e-84	286.0	COG3000@1|root,COG3000@2|Bacteria,2HR3N@201174|Actinobacteria	201174|Actinobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158347_k127_2194164_20	1463881.KL591013_gene1356	1.36e-52	195.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158347_k127_2194164_11	1122611.KB903959_gene4223	2.655e-87	301.0	COG2508@1|root,COG2508@2|Bacteria,2ICUQ@201174|Actinobacteria,4EGD0@85012|Streptosporangiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158347_k127_2194164_1	196162.Noca_3306	1.117e-252	794.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DPFV@85009|Propionibacteriales	201174|Actinobacteria	EH	TPP binding domain protein	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158347_k127_2194164_10	391625.PPSIR1_36477	6.548e-92	318.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,42S6T@68525|delta/epsilon subdivisions,2WSCK@28221|Deltaproteobacteria,2YUY7@29|Myxococcales	28221|Deltaproteobacteria	S	Sodium Bile acid symporter family	yocS	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
SRR25158347_k127_2194164_6	196162.Noca_3305	1.193e-116	383.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DVDZ@85009|Propionibacteriales	201174|Actinobacteria	M	RmlD substrate binding domain	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158347_k127_2194164_17	1122622.ATWJ01000014_gene446	3.656e-59	216.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria,4FFNA@85021|Intrasporangiaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_2194164_29	649638.Trad_0571	3.624e-22	111.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158347_k127_2194164_21	1048339.KB913029_gene1023	3.207e-51	208.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU1E@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_2194164_18	316055.RPE_3782	1.267e-57	228.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TSE7@28211|Alphaproteobacteria,3JRVG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	amino acid	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_2194164_19	604331.AUHY01000113_gene2329	1.095e-53	205.0	COG0410@1|root,COG0410@2|Bacteria,1WM3P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158347_k127_2194164_7	869210.Marky_0691	1.322e-98	330.0	COG2084@1|root,COG2084@2|Bacteria,1WIBK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158347_k127_2194164_26	1440774.Y900_011870	3.392e-31	143.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,235P5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	tcrY	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0046983,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_2194164_24	1173026.Glo7428_2093	7.669e-38	164.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_2194164_16	1463845.JOIG01000005_gene3382	2.041e-66	234.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158347_k127_2195763_11	1169152.AXVD01000023_gene3256	1.502e-46	192.0	COG2021@1|root,COG2021@2|Bacteria,2HIEG@201174|Actinobacteria,4G3VG@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_2195763_13	926554.KI912671_gene265	2.714e-18	98.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CCP_MauG,Copper-bind,Cu-oxidase_3,Cupredoxin_1
SRR25158347_k127_2195763_0	330214.NIDE3519	4.519e-304	985.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
SRR25158347_k127_2195763_6	1449976.KALB_8011	3.2e-126	414.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4DXRE@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_2195763_1	1155718.KB891918_gene4066	2.307e-250	779.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_2195763_5	1137271.AZUM01000015_gene1668	1.136e-133	449.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DYMF@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158347_k127_2195763_9	913865.DOT_6204	4.03e-80	280.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,2624Y@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158347_k127_2195763_2	1415630.U771_17515	2.468e-157	516.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K02056,ko:K10441,ko:K10545,ko:K17215	ko02010,map02010	M00212,M00215,M00221,M00593	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4	-	-	ABC_tran
SRR25158347_k127_2195763_10	1122132.AQYH01000017_gene1024	1.015e-77	271.0	COG2390@1|root,COG2390@2|Bacteria,1MWHQ@1224|Proteobacteria,2TSIT@28211|Alphaproteobacteria,4BJ1K@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sugar-bind
SRR25158347_k127_2195763_3	1144343.PMI41_02739	2.638e-151	498.0	COG1069@1|root,COG1069@2|Bacteria,1MY11@1224|Proteobacteria,2TTQN@28211|Alphaproteobacteria,43N2I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158347_k127_2195763_4	33876.JNXY01000065_gene9341	1.77e-139	452.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DIYT@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_2195763_7	1231190.NA8A_08299	6.577e-125	422.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2TW5I@28211|Alphaproteobacteria,43RA3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	MA20_37380	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158347_k127_2195763_8	1304865.JAGF01000001_gene1580	5.763e-91	305.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158347_k127_2195763_12	1380356.JNIK01000013_gene4175	1.864e-30	125.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158347_k127_2277101_11	1236973.JCM9157_2128	1.143e-13	79.0	COG2234@1|root,COG2234@2|Bacteria,1UHWN@1239|Firmicutes,4HGPC@91061|Bacilli,1ZDXC@1386|Bacillus	91061|Bacilli	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158347_k127_2277101_8	1089455.MOPEL_029_01590	1.461e-61	222.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4F64Z@85018|Dermatophilaceae	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158347_k127_2277101_1	1304874.JAFY01000002_gene516	2.89e-148	483.0	COG0133@1|root,COG0133@2|Bacteria,3TAC4@508458|Synergistetes	508458|Synergistetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_2277101_9	457425.XNR_4842	1.122e-59	224.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158347_k127_2277101_10	555088.DealDRAFT_2391	1.48e-56	211.0	COG0726@1|root,COG0726@2|Bacteria,1TRUR@1239|Firmicutes,24D1N@186801|Clostridia	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158347_k127_2277101_7	1268072.PSAB_09730	1.17e-66	247.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HTQF@91061|Bacilli,275BY@186822|Paenibacillaceae	91061|Bacilli	S	GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
SRR25158347_k127_2277101_6	1122182.KB903821_gene1299	2.741e-69	243.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4DAYF@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158347_k127_2277101_5	1121019.AUMN01000001_gene511	5.616e-78	269.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158347_k127_2277101_4	253839.SSNG_06425	1.353e-79	273.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria	201174|Actinobacteria	E	amino acid ABC transporter	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158347_k127_2277101_2	1122622.ATWJ01000012_gene1038	2.684e-119	387.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4FE5G@85021|Intrasporangiaceae	201174|Actinobacteria	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028,ko:K17076	ko02010,map02010	M00236,M00589	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.20	-	-	ABC_tran
SRR25158347_k127_2277101_0	928724.SacglDRAFT_03421	6.717e-268	832.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4E0IR@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD1	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158347_k127_2277101_3	58123.JOFJ01000021_gene3929	8.842e-85	292.0	COG4677@1|root,COG4677@2|Bacteria,2GNHF@201174|Actinobacteria,4EFJG@85012|Streptosporangiales	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158347_k127_228723_16	1160137.KB907308_gene7819	1.43e-50	189.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4FURW@85025|Nocardiaceae	201174|Actinobacteria	JM	Nucleotidyl transferase	rmlA	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158347_k127_228723_15	1382356.JQMP01000003_gene2210	6.335e-51	197.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,2G6JZ@200795|Chloroflexi,27XJJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158347_k127_228723_20	326427.Cagg_0826	2.458e-17	87.0	COG2076@1|root,COG2076@2|Bacteria,2G94V@200795|Chloroflexi,377JZ@32061|Chloroflexia	32061|Chloroflexia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_228723_10	1461580.CCAS010000022_gene2372	4.811e-79	273.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1ZBZD@1386|Bacillus	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158347_k127_228723_8	368407.Memar_0186	5.038e-122	404.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158347_k127_228723_7	862751.SACTE_2006	1.663e-142	460.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158347_k127_228723_14	665577.JH993790_gene2825	1.427e-54	212.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158347_k127_228723_24	909613.UO65_3876	1.87e-05	56.0	COG0365@1|root,COG0365@2|Bacteria,2I2IW@201174|Actinobacteria,4E2YY@85010|Pseudonocardiales	201174|Actinobacteria	I	TIGRFAM TIGR03089 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158347_k127_228723_1	414684.RC1_1632	9.992e-202	647.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2JPIV@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRR25158347_k127_228723_22	1229780.BN381_130338	9.741e-10	70.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158347_k127_228723_11	266117.Rxyl_1045	3.206e-76	272.0	COG1824@1|root,COG1824@2|Bacteria,2H441@201174|Actinobacteria	201174|Actinobacteria	P	Integral membrane	-	-	-	-	-	-	-	-	-	-	-	-	MgtE
SRR25158347_k127_228723_9	266117.Rxyl_1044	3.629e-109	366.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
SRR25158347_k127_228723_18	58123.JOFJ01000004_gene1880	3.24e-30	128.0	COG1309@1|root,COG1309@2|Bacteria,2GJVD@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_228723_6	926550.CLDAP_05760	1.649e-147	511.0	COG1501@1|root,COG1501@2|Bacteria,2G5TX@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SRR25158347_k127_228723_5	1313172.YM304_20100	5.231e-155	504.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria	201174|Actinobacteria	G	xylulose kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158347_k127_228723_2	351607.Acel_2064	6.372e-190	599.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4EREZ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158347_k127_228723_12	1121272.KB903292_gene3948	2.025e-72	264.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_228723_4	1122611.KB903941_gene2108	1.354e-155	504.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4EI2T@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_228723_17	290397.Adeh_2388	1.287e-35	157.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158347_k127_228723_0	469383.Cwoe_5528	1.205e-237	744.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158347_k127_228723_21	136273.GY22_01915	6.427e-12	73.0	2C2EP@1|root,33H2C@2|Bacteria,2H080@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_228723_3	1108045.GORHZ_068_00060	2.197e-166	546.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4GA3N@85026|Gordoniaceae	201174|Actinobacteria	I	Biotin-lipoyl like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158347_k127_228723_19	2045.KR76_00650	2.874e-21	107.0	COG0741@1|root,COG2951@1|root,COG0741@2|Bacteria,COG2951@2|Bacteria,2IF18@201174|Actinobacteria,4DN6C@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158347_k127_2316388_0	266117.Rxyl_2418	1.484e-170	545.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2316388_5	1121356.AQUW01000002_gene1698	9.342e-20	98.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,22KUH@1653|Corynebacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158347_k127_2316388_3	525904.Tter_2363	9.791e-39	151.0	COG1956@1|root,COG1956@2|Bacteria,2NPKF@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
SRR25158347_k127_2316388_2	570952.ATVH01000014_gene2068	4.911e-77	270.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_2316388_4	1150864.MILUP08_45593	3.946e-30	132.0	COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4DEVK@85008|Micromonosporales	201174|Actinobacteria	S	Thiamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
SRR25158347_k127_2316388_1	298653.Franean1_4888	5.136e-85	297.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4EXBT@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_2323799_4	2002.JOEQ01000001_gene4804	8.054e-149	481.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4EGSR@85012|Streptosporangiales	201174|Actinobacteria	D	Ftsk_gamma	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158347_k127_2323799_21	66874.JOFS01000002_gene7515	2.16e-09	68.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,MDMPI_N,Pentapeptide
SRR25158347_k127_2323799_15	1121468.AUBR01000009_gene2167	1.672e-23	115.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,42J4X@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158347_k127_2323799_6	1214101.BN159_2695	3.017e-123	419.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158347_k127_2323799_14	1229781.C272_09959	2.744e-37	156.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4F8RG@85019|Brevibacteriaceae	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158347_k127_2323799_8	351607.Acel_1497	6.457e-81	287.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158347_k127_2323799_9	1298863.AUEP01000019_gene3529	1.567e-74	259.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DT5X@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158347_k127_2323799_16	1123320.KB889568_gene5425	1.777e-19	100.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158347_k127_2323799_22	502025.Hoch_0904	1.225e-08	65.0	COG0847@1|root,COG0847@2|Bacteria,1PER2@1224|Proteobacteria,42WAS@68525|delta/epsilon subdivisions,2WWG3@28221|Deltaproteobacteria,2Z1FU@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM Exonuclease RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158347_k127_2323799_1	1283287.KB822579_gene2033	6.079e-170	542.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4DPDK@85009|Propionibacteriales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158347_k127_2323799_19	397278.JOJN01000007_gene3406	2.794e-11	76.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4DR2K@85009|Propionibacteriales	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158347_k127_2323799_2	208439.AJAP_27095	1.185e-166	539.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DXJ9@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158347_k127_2323799_12	1394175.AWUN01000006_gene217	1.876e-61	228.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158347_k127_2323799_11	1266908.AQPB01000061_gene1380	8.473e-63	226.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158347_k127_2323799_5	1394178.AWOO02000010_gene4095	6.05e-137	458.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4EFMU@85012|Streptosporangiales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158347_k127_2323799_17	1120958.AULD01000005_gene2123	4.355e-16	88.0	COG1670@1|root,COG1670@2|Bacteria,2IRHX@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,GNAT_acetyltran
SRR25158347_k127_2323799_10	675635.Psed_2122	2.693e-67	236.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4E040@85010|Pseudonocardiales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158347_k127_2323799_24	1122933.JNIY01000003_gene1083	1.459e-05	53.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158347_k127_2323799_13	1313172.YM304_26950	1.571e-38	149.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4CN4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158347_k127_2323799_3	1177179.A11A3_06216	4.984e-162	520.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria,1XID3@135619|Oceanospirillales	135619|Oceanospirillales	C	carnitine dehydratase	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158347_k127_2323799_18	1122138.AQUZ01000030_gene4704	5.635e-13	79.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4DR3M@85009|Propionibacteriales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2323799_20	1460635.JCM19038_1961	1.312e-09	70.0	COG1670@1|root,COG1670@2|Bacteria,1VDXK@1239|Firmicutes,4HNE6@91061|Bacilli	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158347_k127_2323799_7	1229780.BN381_350135	1.658e-102	345.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,3UX9J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR25158347_k127_2323799_23	749927.AMED_4743	3.515e-06	57.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR25158347_k127_2323799_0	469371.Tbis_2425	0.0	1149.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4DY0W@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158347_k127_2334455_2	471853.Bcav_0518	1.371e-50	187.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158347_k127_2334455_3	390989.JOEG01000001_gene5424	1.912e-16	92.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DAIZ@85008|Micromonosporales	201174|Actinobacteria	G	Starch synthase catalytic domain	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2334455_1	1382359.JIAL01000001_gene2422	1.009e-230	733.0	COG0366@1|root,COG0366@2|Bacteria,3Y2ZW@57723|Acidobacteria,2JICY@204432|Acidobacteriia	204432|Acidobacteriia	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158347_k127_2334455_0	867845.KI911784_gene1529	6.797e-296	925.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G7K6@200795|Chloroflexi,374W8@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
SRR25158347_k127_2336663_40	1121366.KB892469_gene1701	5.99e-09	60.0	COG0454@1|root,COG0456@2|Bacteria,2HV2Z@201174|Actinobacteria,22PHA@1653|Corynebacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_2336663_32	81824.XP_001750264.1	7.177e-40	161.0	COG0622@1|root,COG1028@1|root,COG3217@1|root,KOG1208@2759|Eukaryota,KOG2362@2759|Eukaryota,KOG3325@2759|Eukaryota,38G09@33154|Opisthokonta	33154|Opisthokonta	U	retrograde transport, endosome to Golgi	VPS29	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005829,GO:0006810,GO:0006886,GO:0006892,GO:0006896,GO:0007034,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0008104,GO:0008150,GO:0008270,GO:0009987,GO:0010008,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016055,GO:0016192,GO:0016197,GO:0016482,GO:0016787,GO:0023052,GO:0030904,GO:0030906,GO:0031090,GO:0031410,GO:0031902,GO:0031982,GO:0032991,GO:0033036,GO:0034613,GO:0042147,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046872,GO:0046907,GO:0046914,GO:0048193,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0065007,GO:0070727,GO:0071702,GO:0071705,GO:0097708,GO:0098588,GO:0098796,GO:0098805,GO:0098876,GO:0198738,GO:1905114,GO:1990126	-	ko:K07095,ko:K18467	ko04144,map04144	-	-	-	ko00000,ko00001,ko04131	-	-	-	Metallophos_2
SRR25158347_k127_2336663_9	1112204.GPOL_c47840	4.516e-130	427.0	COG5361@1|root,COG5361@2|Bacteria,2HES3@201174|Actinobacteria,4GH56@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
SRR25158347_k127_2336663_20	1112204.GPOL_c47830	1.345e-89	310.0	COG0438@1|root,COG0438@2|Bacteria,2I7GS@201174|Actinobacteria,4GG64@85026|Gordoniaceae	201174|Actinobacteria	M	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158347_k127_2336663_38	1380370.JIBA01000013_gene1578	6.879e-18	91.0	2F668@1|root,33YQB@2|Bacteria,2GVVI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2336663_18	1380370.JIBA01000013_gene1577	1.333e-90	331.0	COG1511@1|root,COG1511@2|Bacteria,2I9VF@201174|Actinobacteria	201174|Actinobacteria	S	domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
SRR25158347_k127_2336663_16	316274.Haur_0016	2.056e-95	323.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158347_k127_2336663_11	1120949.KB903295_gene2365	5.131e-122	397.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4DC9P@85008|Micromonosporales	201174|Actinobacteria	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158347_k127_2336663_0	1123392.AQWL01000002_gene1698	0.0	1051.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KS0K@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158347_k127_2336663_22	443218.AS9A_2146	2.605e-70	244.0	2CAJE@1|root,33XCP@2|Bacteria,2IMDF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2336663_37	997296.PB1_09077	5.157e-19	99.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1,PG_binding_1,SH3_3,SH3_4,SH3_8,SLH
SRR25158347_k127_2336663_36	59931.WH7805_01907	1.738e-20	105.0	COG0860@1|root,COG0860@2|Bacteria,1G34A@1117|Cyanobacteria,1GZA0@1129|Synechococcus	1117|Cyanobacteria	M	Cell wall hydrolase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRR25158347_k127_2336663_26	1122622.ATWJ01000007_gene1705	1.354e-64	237.0	COG3544@1|root,COG3544@2|Bacteria,2IFX2@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158347_k127_2336663_19	390989.JOEG01000018_gene3545	2.229e-90	310.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria,4D8W7@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K13633	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
SRR25158347_k127_2336663_1	1136417.AZWE01000007_gene1911	1.363e-267	852.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4DA3C@85008|Micromonosporales	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158347_k127_2336663_3	644283.Micau_3065	3.529e-192	616.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158347_k127_2336663_35	284031.JNXD01000045_gene7247	1.666e-22	108.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria	201174|Actinobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158347_k127_2336663_6	1127134.NOCYR_3179	1.98e-144	494.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria,4FVRH@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta-hydrolase family N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158347_k127_2336663_25	292459.STH1268	1.049e-66	248.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
SRR25158347_k127_2336663_34	644548.SCNU_09694	1.036e-22	102.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4GEGV@85026|Gordoniaceae	201174|Actinobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158347_k127_2336663_24	1229780.BN381_250052	4.242e-67	236.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,3UXBM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158347_k127_2336663_15	1313172.YM304_37330	1.237e-100	337.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria	201174|Actinobacteria	P	Molybdate ABC transporter	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR25158347_k127_2336663_13	1313172.YM304_37340	4.04e-105	357.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CNQZ@84992|Acidimicrobiia	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.29	ko:K02017,ko:K02052	ko02010,ko02024,map02010,map02024	M00189,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.8	-	-	ABC_tran,TOBE,TOBE_2
SRR25158347_k127_2336663_5	1380347.JNII01000005_gene3293	3.287e-155	499.0	COG2072@1|root,COG2072@2|Bacteria,2GMDH@201174|Actinobacteria,4EVBF@85013|Frankiales	201174|Actinobacteria	C	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158347_k127_2336663_27	67352.JODS01000017_gene2960	1.266e-58	222.0	COG0738@1|root,COG0738@2|Bacteria,2I8UP@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_2336663_4	927677.ALVU02000004_gene4738	5.253e-161	539.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,DUF4062,NB-ARC,TPR_12
SRR25158347_k127_2336663_33	298655.KI912266_gene3738	2.643e-28	129.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EVA2@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_2336663_39	1157490.EL26_22655	3.428e-11	74.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,27A54@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158347_k127_2336663_14	926560.KE387023_gene2481	1.102e-100	340.0	COG0667@1|root,COG0667@2|Bacteria,1WM4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_2336663_2	1214101.BN159_8121	6.111e-232	747.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158347_k127_2336663_8	1869.MB27_00895	9.284e-131	430.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4D92Y@85008|Micromonosporales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158347_k127_2336663_17	1137271.AZUM01000001_gene708	1.367e-94	317.0	COG0861@1|root,COG0861@2|Bacteria,2GRV3@201174|Actinobacteria,4E9FT@85010|Pseudonocardiales	201174|Actinobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
SRR25158347_k127_2336663_21	1048339.KB913029_gene1428	2.093e-77	264.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4ESN7@85013|Frankiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158347_k127_2336663_31	28042.GU90_13500	3.875e-50	183.0	COG1846@1|root,COG1846@2|Bacteria,2GMV1@201174|Actinobacteria,4E5Q4@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158347_k127_2336663_10	1906.SFRA_14685	1.563e-129	426.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
SRR25158347_k127_2336663_29	526225.Gobs_4720	5.085e-51	196.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4ET2T@85013|Frankiales	201174|Actinobacteria	T	low molecular weight	arsC	-	1.20.4.1,2.8.4.2	ko:K03741,ko:K18701	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158347_k127_2336663_30	222534.KB893729_gene5672	1.91e-50	194.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria,4EV3E@85013|Frankiales	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
SRR25158347_k127_2336663_28	1110697.NCAST_19_00550	2.224e-52	192.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria,4FZTR@85025|Nocardiaceae	201174|Actinobacteria	KT	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,LMWPc
SRR25158347_k127_2336663_7	227882.SAV_1697	1.757e-134	451.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158347_k127_2336663_23	1122247.C731_2751	2.617e-69	248.0	COG0741@1|root,COG2027@1|root,COG0741@2|Bacteria,COG2027@2|Bacteria,2IBCH@201174|Actinobacteria,2359I@1762|Mycobacteriaceae	201174|Actinobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460,NLPC_P60,SLT,SLT_2
SRR25158347_k127_2336663_12	110319.CF8_2620	6.286e-109	366.0	COG1404@1|root,COG1404@2|Bacteria,2I8MD@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Malectin,Peptidase_S8,SLH,fn3_5
SRR25158347_k127_2351009_11	1043493.BBLU01000027_gene1873	7.709e-30	136.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158347_k127_2351009_5	1298880.AUEV01000002_gene1429	1.645e-75	269.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158347_k127_2351009_0	298654.FraEuI1c_5151	9.439e-205	645.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4ERC5@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158347_k127_2351009_13	1451261.AS96_10955	1.971e-20	100.0	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4FPK5@85023|Microbacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158347_k127_2351009_7	1122602.ATXP01000006_gene17	2.329e-55	201.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,1W91N@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158347_k127_2351009_9	762963.HMPREF9056_01038	1.047e-44	184.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4D3I7@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
SRR25158347_k127_2351009_3	555079.Toce_2072	1.263e-122	406.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,42FEW@68295|Thermoanaerobacterales	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158347_k127_2351009_6	500635.MITSMUL_04336	1.118e-68	245.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158347_k127_2351009_12	665956.HMPREF1032_03141	1.262e-26	111.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158347_k127_2351009_10	1210045.ALNP01000002_gene4032	1.273e-41	163.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158347_k127_2351009_2	1449353.JQMQ01000005_gene2195	7.468e-152	499.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,2NGE4@228398|Streptacidiphilus	201174|Actinobacteria	K	Rho termination factor, RNA-binding domain	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158347_k127_2351009_4	1552123.EP57_02465	1.415e-78	270.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,26K04@186820|Listeriaceae	91061|Bacilli	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU37110	TAL_FSA
SRR25158347_k127_2351009_8	1869.MB27_13435	1.61e-46	181.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4DBAU@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158347_k127_2351009_1	443255.SCLAV_4251	8.955e-161	514.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_2351009_14	1125779.HMPREF1219_00305	5.197e-08	55.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,22JKX@1653|Corynebacteriaceae	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158347_k127_2394599_1	767029.HMPREF9154_0459	1.881e-25	118.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4DQJC@85009|Propionibacteriales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158347_k127_2394599_0	593907.Celgi_2834	1.535e-69	246.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4F0QH@85016|Cellulomonadaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158347_k127_2394599_4	391037.Sare_5047	7.07e-07	55.0	COG1977@1|root,COG1977@2|Bacteria,2IQIT@201174|Actinobacteria,4DFX3@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158347_k127_2394599_3	1305737.JAFX01000001_gene3079	8.772e-18	100.0	COG1361@1|root,COG1361@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
SRR25158347_k127_2394599_2	1120959.ATXF01000007_gene2169	1.258e-23	120.0	2CA6S@1|root,2Z9P6@2|Bacteria,2IAT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2400855_3	247634.GPB2148_1531	1.74e-30	132.0	2ARTX@1|root,31H5E@2|Bacteria,1NRN2@1224|Proteobacteria,1SKPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2400855_2	1160137.KB907307_gene3162	3.319e-46	188.0	COG0451@1|root,COG0451@2|Bacteria,2HJB2@201174|Actinobacteria,4G65V@85025|Nocardiaceae	201174|Actinobacteria	GM	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2400855_6	340099.Teth39_1224	8.562e-07	61.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158347_k127_2400855_4	1121933.AUHH01000022_gene2486	3.065e-30	136.0	COG1413@1|root,COG1413@2|Bacteria,2GITU@201174|Actinobacteria,4DVW4@85009|Propionibacteriales	201174|Actinobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158347_k127_2400855_5	1380347.JNII01000007_gene497	2.954e-18	95.0	2CBE1@1|root,32RT5@2|Bacteria,2IQDS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2400855_0	247634.GPB2148_1768	8.604e-91	309.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,1RR2S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Sulfotransferase domain	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
SRR25158347_k127_2400855_1	1245469.S58_14260	2.708e-62	240.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2TQQR@28211|Alphaproteobacteria,3JV0E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,NB-ARC,TPR_4,Trans_reg_C
SRR25158347_k127_2401246_14	1089551.KE386572_gene1955	1.578e-32	133.0	COG3119@1|root,COG3119@2|Bacteria,1MYHH@1224|Proteobacteria,2UA67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_2401246_7	2002.JOEQ01000001_gene4858	2.633e-85	289.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,4EGRA@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158347_k127_2401246_10	1236902.ANAS01000031_gene2833	2.107e-52	196.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,4EJ10@85012|Streptosporangiales	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
SRR25158347_k127_2401246_16	291985.CCSI01000001_gene2075	1.104e-19	104.0	COG0454@1|root,COG0456@2|Bacteria,1QWIU@1224|Proteobacteria,2TWYI@28211|Alphaproteobacteria,2KEG9@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_2401246_11	1227457.C451_10595	8.379e-45	183.0	COG0477@1|root,arCOG00130@2157|Archaea,2XV7S@28890|Euryarchaeota,23U27@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_2401246_1	378806.STAUR_2700	9.014e-166	538.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,4376B@68525|delta/epsilon subdivisions,2X25W@28221|Deltaproteobacteria,2YZ9U@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158347_k127_2401246_3	1146883.BLASA_1733	1.666e-136	455.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4ERKK@85013|Frankiales	201174|Actinobacteria	S	PFAM oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158347_k127_2401246_15	1535287.JP74_00905	1.028e-19	103.0	COG1653@1|root,COG1653@2|Bacteria,1NC43@1224|Proteobacteria,2U3SD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
SRR25158347_k127_2401246_13	710111.FraQA3DRAFT_0422	8.888e-37	160.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EV7C@85013|Frankiales	201174|Actinobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR25158347_k127_2401246_9	298655.KI912266_gene991	3.218e-63	224.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_2401246_5	208439.AJAP_11405	1.703e-116	390.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria,4E03X@85010|Pseudonocardiales	201174|Actinobacteria	S	amine oxidase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,DUF1365
SRR25158347_k127_2401246_12	1265502.KB905939_gene2357	3.063e-42	171.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
SRR25158347_k127_2401246_6	338966.Ppro_0127	3.562e-115	391.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WKGA@28221|Deltaproteobacteria,43TGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,DUF1365
SRR25158347_k127_2401246_4	1266914.ATUK01000010_gene1295	4.954e-125	409.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158347_k127_2401246_0	215803.DB30_8023	6.647e-274	867.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2X7DH@28221|Deltaproteobacteria,2YUKN@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SRR25158347_k127_2401246_8	479432.Sros_1325	1.5e-76	266.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4EGK7@85012|Streptosporangiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158347_k127_2401246_2	1304275.C41B8_03431	2.872e-150	489.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158347_k127_2439798_13	1267533.KB906734_gene3641	1.177e-16	80.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158347_k127_2439798_2	243231.GSU2860	3.043e-299	932.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158347_k127_2439798_4	561175.KB894099_gene5137	9.657e-65	227.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4EIRR@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158347_k127_2439798_6	1348663.KCH_33230	2.561e-60	216.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,2M2SW@2063|Kitasatospora	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158347_k127_2439798_0	1380356.JNIK01000018_gene665	0.0	1619.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4ERS7@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158347_k127_2439798_1	929712.KI912613_gene4955	0.0	1296.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158347_k127_2439798_9	1033730.CAHG01000004_gene61	1.207e-46	179.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4DQS8@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158347_k127_2439798_10	1828.JOKB01000008_gene259	1.162e-44	173.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4FX2F@85025|Nocardiaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158347_k127_2439798_16	251229.Chro_1463	8.887e-07	57.0	COG0745@1|root,COG0745@2|Bacteria,1G0UR@1117|Cyanobacteria,3VIF3@52604|Pleurocapsales	1117|Cyanobacteria	KT	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2439798_3	1120954.ATXE01000004_gene9	1.01e-80	284.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4DNBG@85009|Propionibacteriales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158347_k127_2439798_5	290512.Paes_0284	1.087e-61	221.0	COG0080@1|root,COG0080@2|Bacteria,1FDVE@1090|Chlorobi	1090|Chlorobi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158347_k127_2439798_7	471857.Svir_03630	7.222e-59	215.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4E05Z@85010|Pseudonocardiales	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158347_k127_2439798_15	479432.Sros_1067	6.295e-07	55.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4EKPQ@85012|Streptosporangiales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158347_k127_2439798_17	207954.MED92_04552	3.359e-05	47.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158347_k127_2439798_12	1348663.KCH_33590	1.067e-18	93.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,2M2VW@2063|Kitasatospora	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158347_k127_2439798_11	479432.Sros_0741	2.23e-20	98.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4EJ7Q@85012|Streptosporangiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158347_k127_2439798_14	548479.HMPREF0573_11137	2.373e-16	79.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4D6F6@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158347_k127_2439798_8	351607.Acel_0304	7.311e-57	198.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158347_k127_2444186_5	886293.Sinac_7569	1.667e-17	97.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
SRR25158347_k127_2444186_3	886293.Sinac_7570	1.501e-148	483.0	COG2242@1|root,COG2242@2|Bacteria,2J25Y@203682|Planctomycetes	203682|Planctomycetes	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2444186_1	1003195.SCAT_2211	1.172e-191	614.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158347_k127_2444186_4	1223523.H340_30338	2.665e-22	108.0	COG4279@1|root,COG4279@2|Bacteria,2GIYW@201174|Actinobacteria	201174|Actinobacteria	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2444186_0	405948.SACE_3090	1.527e-260	835.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4E9V6@85010|Pseudonocardiales	201174|Actinobacteria	KL	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
SRR25158347_k127_2444186_2	196162.Noca_4679	1.102e-153	514.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,CHU_C,DUF11,PKD,Peptidase_M30
SRR25158347_k127_2450178_2	1403819.BATR01000022_gene806	1.188e-78	277.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158347_k127_2450178_1	875328.JDM601_2174	2.662e-84	287.0	COG1024@1|root,COG1024@2|Bacteria,2H2U8@201174|Actinobacteria,23AUU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_2450178_3	1133849.O3I_017120	2.135e-65	228.0	COG3832@1|root,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,4G1HM@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_2450178_5	1463909.KL585972_gene3575	1.022e-31	128.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158347_k127_2450178_4	710111.FraQA3DRAFT_1911	5.219e-48	190.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria,4EVF3@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158347_k127_2474895_14	997296.PB1_14879	8.087e-10	70.0	COG2345@1|root,COG2345@2|Bacteria,1UYQM@1239|Firmicutes,4HAZZ@91061|Bacilli,1ZC2X@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase,HTH_20
SRR25158347_k127_2474895_9	285514.JNWO01000005_gene2173	1.468e-21	100.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158347_k127_2474895_11	1043493.BBLU01000017_gene1383	2.484e-17	92.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	thiX	-	1.8.1.8	ko:K02199,ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	AhpC-TSA,Thioredoxin
SRR25158347_k127_2474895_1	644282.Deba_3251	2.411e-95	332.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2474895_10	570268.ANBB01000089_gene755	1.038e-18	98.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4EH49@85012|Streptosporangiales	201174|Actinobacteria	S	Glycine cleavage T-protein C-terminal barrel domain	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158347_k127_2474895_2	349124.Hhal_0101	8.614e-56	200.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WXZK@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158347_k127_2474895_13	351607.Acel_0064	2.354e-13	83.0	COG0457@1|root,COG0457@2|Bacteria	351607.Acel_0064|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2474895_12	1463854.JOHT01000025_gene1154	8.879e-16	88.0	2DP8R@1|root,32UKH@2|Bacteria,2IFBP@201174|Actinobacteria	201174|Actinobacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2474895_7	1352941.M877_19290	1.576e-27	117.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2474895_3	469383.Cwoe_4475	1.545e-49	185.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria	201174|Actinobacteria	T	HD-GYP domain	-	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HD_5
SRR25158347_k127_2474895_4	1176165.CAJD01000022_gene1834	1.36e-37	160.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4F9G0@85019|Brevibacteriaceae	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158347_k127_2474895_5	471852.Tcur_0663	3.705e-35	144.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4EJT0@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158347_k127_2474895_6	926569.ANT_19370	9.47e-28	126.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158347_k127_2474895_0	561175.KB894099_gene4996	3.225e-102	347.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4EFJR@85012|Streptosporangiales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2474895_8	58123.JOFJ01000020_gene3727	2.19e-23	106.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4EIHS@85012|Streptosporangiales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158347_k127_2476420_0	1122138.AQUZ01000002_gene2132	1.743e-244	792.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DSSQ@85009|Propionibacteriales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8,fn3_5
SRR25158347_k127_2476420_2	469371.Tbis_1953	5.586e-155	514.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DZ2U@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_2476420_9	411483.FAEPRAA2165_00426	5.804e-15	87.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158347_k127_2476420_1	1110697.NCAST_30_00230	5.844e-178	565.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4FW26@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_2476420_4	1229780.BN381_110088	4.87e-105	347.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,3UX9A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_2476420_7	882083.SacmaDRAFT_1683	2.539e-27	128.0	COG2755@1|root,COG2755@2|Bacteria,2GR6W@201174|Actinobacteria,4DZQ1@85010|Pseudonocardiales	201174|Actinobacteria	E	O-octanoyltransferase activity	octT	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008374,GO:0009987,GO:0016020,GO:0016043,GO:0016414,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0040007,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051262,GO:0065003,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158347_k127_2476420_6	2002.JOEQ01000002_gene4533	4.583e-67	244.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4EHEQ@85012|Streptosporangiales	201174|Actinobacteria	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158347_k127_2476420_10	105422.BBPM01000015_gene1941	0.0003158	49.0	2E5D5@1|root,33055@2|Bacteria,2IR7Y@201174|Actinobacteria,2NJIS@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2476420_5	1114959.SZMC14600_16436	4.706e-78	287.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4DXM2@85010|Pseudonocardiales	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158347_k127_2476420_3	1961.JOAK01000014_gene5640	1.802e-130	430.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158347_k127_2476420_8	479432.Sros_8868	2.408e-22	102.0	COG1309@1|root,COG1309@2|Bacteria,2H131@201174|Actinobacteria,4EQC9@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2487730_0	51511.ENSCSAVP00000014409	4.753e-05	55.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,481TV@7711|Chordata	33208|Metazoa	O	matrix metallopeptidase 19	MMP19	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564	3.4.24.80	ko:K07763,ko:K07998	ko04668,ko04912,map04668,map04912	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hemopexin,PG_binding_1,Peptidase_M10
SRR25158347_k127_2496328_5	1192034.CAP_4131	1.161e-85	293.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria,2YTTX@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158347_k127_2496328_14	309807.SRU_1573	1.762e-12	73.0	COG0346@1|root,COG1073@1|root,COG0346@2|Bacteria,COG1073@2|Bacteria,4NNGG@976|Bacteroidetes,1FK1H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158347_k127_2496328_3	479434.Sthe_0598	1.648e-120	429.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158347_k127_2496328_2	298654.FraEuI1c_5742	1.797e-136	446.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4EU1D@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2496328_1	1120936.KB907210_gene5949	2.927e-138	469.0	COG1073@1|root,COG1073@2|Bacteria,2I52S@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496328_8	1442599.JAAN01000030_gene2079	1.012e-79	287.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158347_k127_2496328_4	871968.DESME_05950	3.782e-97	342.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,2600W@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158347_k127_2496328_17	710111.FraQA3DRAFT_5561	5.356e-06	59.0	2C4RB@1|root,2ZVRN@2|Bacteria,2HAZK@201174|Actinobacteria,4EWZ7@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496328_6	106370.Francci3_3810	2.41e-81	282.0	COG1192@1|root,COG1192@2|Bacteria,2GNEQ@201174|Actinobacteria	201174|Actinobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_2496328_0	1385521.N803_09610	1.788e-151	496.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4FERS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158347_k127_2496328_11	1074488.AGBX01000006_gene2127	1.206e-33	137.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria,4FDJ1@85020|Dermabacteraceae	201174|Actinobacteria	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158347_k127_2496328_16	1123020.AUIE01000005_gene4249	4.169e-08	63.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1YD9Z@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158347_k127_2496328_15	543632.JOJL01000003_gene8513	1.196e-09	68.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl
SRR25158347_k127_2496328_9	1246445.ANAY01000001_gene389	1.739e-65	233.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4EG9R@85012|Streptosporangiales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158347_k127_2496328_13	1121946.AUAX01000045_gene7514	2.026e-24	106.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4DFT4@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158347_k127_2496328_7	479431.Namu_2001	2.919e-81	286.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4ESB1@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,PLDc_N
SRR25158347_k127_2496328_12	67275.JOAP01000020_gene2003	8.43e-28	122.0	COG1277@1|root,COG1277@2|Bacteria,2GSIR@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158347_k127_2496328_10	1206744.BAGL01000035_gene418	3.766e-58	205.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FWEK@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2496739_9	1312954.KI914890_gene2243	5.532e-107	369.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,1W808@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158347_k127_2496739_25	136273.GY22_15020	5.606e-34	143.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,1W9BK@1268|Micrococcaceae	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
SRR25158347_k127_2496739_32	1313172.YM304_38430	3.142e-15	87.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496739_27	105425.BBPL01000004_gene7753	4.991e-24	119.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,2NFDZ@228398|Streptacidiphilus	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158347_k127_2496739_35	1449353.JQMQ01000005_gene4804	1.798e-12	71.0	2ERD0@1|root,33IYN@2|Bacteria,2GXC0@201174|Actinobacteria,2NJ2I@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496739_2	367299.JOEE01000008_gene383	4.053e-268	868.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4FEK0@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158347_k127_2496739_43	1179773.BN6_60160	0.0007012	53.0	COG1361@1|root,COG2373@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
SRR25158347_k127_2496739_5	471852.Tcur_2940	4.489e-121	401.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4EH2D@85012|Streptosporangiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158347_k127_2496739_18	1206720.BAFQ01000187_gene4843	7.638e-58	210.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria,4FVKX@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496739_26	1394178.AWOO02000072_gene443	6.478e-34	142.0	COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_2496739_29	1304865.JAGF01000001_gene613	1.998e-19	98.0	COG0681@1|root,COG0681@2|Bacteria,2GX48@201174|Actinobacteria	201174|Actinobacteria	U	TIGRFAM peptidase S26B, signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158347_k127_2496739_22	351607.Acel_2032	2.397e-46	179.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4ESHR@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase, sigma 28 subunit	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_2496739_39	1095772.CAHH01000059_gene1400	4.751e-06	59.0	2E49S@1|root,32Z5G@2|Bacteria,2IHN1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR25158347_k127_2496739_21	106370.Francci3_1403	1.321e-48	198.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4ERJY@85013|Frankiales	201174|Actinobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158347_k127_2496739_19	446470.Snas_4916	2.364e-54	206.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4EYP0@85014|Glycomycetales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158347_k127_2496739_8	390989.JOEG01000008_gene1350	3.955e-115	379.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4D9JV@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_2496739_28	469371.Tbis_1516	1.983e-19	100.0	COG1309@1|root,COG1309@2|Bacteria,2GJHJ@201174|Actinobacteria,4E52H@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2496739_23	390989.JOEG01000008_gene1345	6.413e-42	158.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4DD2W@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158347_k127_2496739_14	498761.HM1_2051	6.656e-80	284.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158347_k127_2496739_7	351607.Acel_1004	1.298e-119	410.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4ERN7@85013|Frankiales	201174|Actinobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158347_k127_2496739_4	1048339.KB913029_gene4581	2.641e-123	413.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4ES9W@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_2496739_11	1274.HX89_05910	1.583e-100	356.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,1ZVQN@145357|Dermacoccaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_2496739_10	1146883.BLASA_2217	1.066e-103	363.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4ERUH@85013|Frankiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158347_k127_2496739_12	471852.Tcur_2927	4.014e-88	307.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4EI9C@85012|Streptosporangiales	201174|Actinobacteria	D	Cell cycle protein	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
SRR25158347_k127_2496739_15	867903.ThesuDRAFT_01660	2.325e-69	263.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3WCJ3@538999|Clostridiales incertae sedis	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158347_k127_2496739_6	1123320.KB889576_gene1978	4.971e-121	405.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_2496739_17	1122927.KB895415_gene4600	2.274e-62	227.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRR25158347_k127_2496739_34	1380347.JNII01000008_gene4202	2.161e-13	79.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4ETEJ@85013|Frankiales	201174|Actinobacteria	M	Essential cell division protein	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158347_k127_2496739_3	146922.JOFU01000006_gene2826	5.327e-160	514.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158347_k127_2496739_24	471853.Bcav_2406	8.619e-37	149.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158347_k127_2496739_20	1125863.JAFN01000001_gene2304	2.966e-49	185.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158347_k127_2496739_33	1123023.JIAI01000009_gene1062	5.584e-15	83.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4E37Y@85010|Pseudonocardiales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158347_k127_2496739_37	883169.HMPREF9719_00249	5.593e-07	55.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,22NXI@1653|Corynebacteriaceae	201174|Actinobacteria	S	Integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158347_k127_2496739_38	767817.Desgi_3616	4.48e-06	58.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,262G3@186807|Peptococcaceae	186801|Clostridia	D	PFAM DivIVA	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158347_k127_2496739_40	1121019.AUMN01000002_gene352	9.115e-05	53.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,1W8KS@1268|Micrococcaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158347_k127_2496739_36	521674.Plim_2641	3.811e-07	61.0	2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496739_0	351607.Acel_1029	0.0	1151.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4ERW9@85013|Frankiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158347_k127_2496739_30	1209989.TepiRe1_1592	3.481e-18	92.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,42FT9@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM sporulation protein, yteA	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158347_k127_2496739_31	196164.23493874	6.675e-18	91.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,22NA4@1653|Corynebacteriaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158347_k127_2496739_16	1380390.JIAT01000010_gene4530	2.449e-68	245.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158347_k127_2496739_42	369723.Strop_3200	0.0002762	52.0	2FHDP@1|root,3497V@2|Bacteria,2IEDM@201174|Actinobacteria,4DB08@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2496739_1	351607.Acel_1054	0.0	1145.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERD2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158347_k127_2496739_13	1283287.KB822577_gene3218	1.468e-83	298.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DTUR@85009|Propionibacteriales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRR25158347_k127_2496739_41	1101188.KI912155_gene2182	0.000133	54.0	COG0642@1|root,COG0642@2|Bacteria,2I58H@201174|Actinobacteria	201174|Actinobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
SRR25158347_k127_2504261_3	1150398.JIBJ01000011_gene2289	4.486e-09	61.0	COG0346@1|root,COG0346@2|Bacteria,2IRQX@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_2504261_4	234267.Acid_2380	5.413e-08	66.0	COG2133@1|root,COG3292@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1906,Glyco_hydro_18,Malectin,PA14,SLH,VCBS
SRR25158347_k127_2504261_1	1229780.BN381_10243	9.888e-70	248.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_2504261_0	1048339.KB913029_gene4038	1.02e-99	352.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_2504261_2	1229780.BN381_10243	5.702e-50	194.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_2506134_6	1121022.ABENE_14000	0.0004411	54.0	COG4625@1|root,COG4625@2|Bacteria,1PDVH@1224|Proteobacteria,2UNP6@28211|Alphaproteobacteria,2KHWK@204458|Caulobacterales	204458|Caulobacterales	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2506134_4	118161.KB235922_gene5902	1.365e-17	99.0	COG2133@1|root,COG2373@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,1G2CB@1117|Cyanobacteria,3VM5E@52604|Pleurocapsales	1117|Cyanobacteria	GQ	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,PA14
SRR25158347_k127_2506134_5	662479.C440_05942	4.038e-09	66.0	COG0681@1|root,arCOG01740@2157|Archaea,2XTAK@28890|Euryarchaeota,23RXS@183963|Halobacteria	183963|Halobacteria	U	Signal peptidase I	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158347_k127_2506134_2	37919.EP51_33610	1.387e-30	132.0	COG2267@1|root,COG2267@2|Bacteria,2I488@201174|Actinobacteria,4G8K6@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158347_k127_2506134_7	1123251.ATWM01000006_gene2153	0.0006091	52.0	28PF4@1|root,2ZC6F@2|Bacteria,2HXZV@201174|Actinobacteria,4FIXW@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2506134_0	365044.Pnap_1801	1.503e-54	194.0	COG0346@1|root,COG0346@2|Bacteria,1RI3Q@1224|Proteobacteria,2VSN7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_2506134_1	882083.SacmaDRAFT_3406	3.748e-42	166.0	COG1975@1|root,COG1975@2|Bacteria,2IK3Z@201174|Actinobacteria,4E427@85010|Pseudonocardiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C
SRR25158347_k127_2506134_3	485913.Krac_9652	4.124e-25	114.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_2536839_1	479431.Namu_4670	1.532e-72	251.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4ERG0@85013|Frankiales	201174|Actinobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2536839_3	1449976.KALB_1041	1.961e-52	206.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,4E07F@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_2536839_11	1454004.AW11_02452	0.0008695	50.0	COG2197@1|root,COG2197@2|Bacteria,1N5IE@1224|Proteobacteria,2W4QA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_2536839_2	1121946.AUAX01000001_gene2532	2.047e-67	246.0	2AUNZ@1|root,31KBW@2|Bacteria,2GP4I@201174|Actinobacteria,4DBCM@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786
SRR25158347_k127_2536839_8	875328.JDM601_0449	1.117e-14	87.0	2ENRQ@1|root,33GCV@2|Bacteria,2H0SX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2536839_4	875328.JDM601_0447	2.715e-50	185.0	COG5573@1|root,COG5573@2|Bacteria,2GY55@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_2536839_0	1385521.N803_14125	5.576e-76	260.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria	201174|Actinobacteria	C	pyridoxamine 5-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158347_k127_2536839_9	1162668.LFE_0082	1.798e-11	76.0	2DQ7K@1|root,32UNK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2536839_6	235985.BBPN01000003_gene4736	1.358e-29	138.0	COG1511@1|root,COG2268@1|root,COG5164@1|root,COG1511@2|Bacteria,COG2268@2|Bacteria,COG5164@2|Bacteria,2I4DZ@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2536839_5	208444.JNYY01000001_gene5158	2.027e-44	186.0	2APEP@1|root,31EHC@2|Bacteria,2H5GN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2536839_10	680198.SCAB_85371	2.923e-11	77.0	2F3YA@1|root,33WQA@2|Bacteria,2IG3Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2536839_7	1179773.BN6_42600	2.098e-16	91.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria,4E0XU@85010|Pseudonocardiales	201174|Actinobacteria	S	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
SRR25158347_k127_2612392_5	483219.LILAB_07715	7.951e-27	127.0	COG0682@1|root,COG0682@2|Bacteria,1Q2R4@1224|Proteobacteria,438CQ@68525|delta/epsilon subdivisions,2WP0G@28221|Deltaproteobacteria,2YWK4@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158347_k127_2612392_2	1128421.JAGA01000002_gene1691	9.854e-84	299.0	COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158347_k127_2612392_1	1128421.JAGA01000002_gene1692	7.629e-113	384.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158347_k127_2612392_0	1128421.JAGA01000002_gene1693	4.417e-132	429.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_2612392_4	485913.Krac_3255	4.976e-50	202.0	COG1233@1|root,COG1233@2|Bacteria,2G8AW@200795|Chloroflexi	200795|Chloroflexi	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158347_k127_2612392_3	446470.Snas_3848	2.325e-79	274.0	COG1595@1|root,COG3631@1|root,COG1595@2|Bacteria,COG3631@2|Bacteria,2GKBH@201174|Actinobacteria,4EZI8@85014|Glycomycetales	201174|Actinobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158347_k127_2626999_1	1210045.ALNP01000005_gene3726	3.558e-91	318.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158347_k127_2626999_2	525909.Afer_0762	2.933e-87	293.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158347_k127_2626999_0	1120936.KB907209_gene1818	8.712e-205	647.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4EI0M@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158347_k127_2626999_3	1205680.CAKO01000040_gene784	8.33e-84	299.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2TTP9@28211|Alphaproteobacteria,2JRMN@204441|Rhodospirillales	204441|Rhodospirillales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_2626999_4	1120950.KB892769_gene5415	6.534e-17	92.0	COG1595@1|root,COG1595@2|Bacteria,2GRZW@201174|Actinobacteria,4DSMI@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158347_k127_2629896_1	1043493.BBLU01000005_gene1971	1.188e-44	168.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158347_k127_2629896_0	471852.Tcur_0238	1.305e-279	872.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4EFTK@85012|Streptosporangiales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158347_k127_2629896_2	1382304.JNIL01000001_gene3007	3.831e-38	161.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,2787M@186823|Alicyclobacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRR25158347_k127_2629896_4	1173027.Mic7113_4502	4.077e-32	132.0	COG0784@1|root,COG0784@2|Bacteria,1G7QU@1117|Cyanobacteria,1HCMB@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_2629896_3	1000565.METUNv1_02363	2.027e-37	153.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJX9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
SRR25158347_k127_2630493_4	926569.ANT_01210	5.631e-128	413.0	COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158347_k127_2630493_1	1348663.KCH_72370	4.668e-158	512.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,2M0ZR@2063|Kitasatospora	201174|Actinobacteria	F	Amidohydrolase family	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158347_k127_2630493_7	1297617.JPJD01000047_gene1362	7.428e-40	155.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158347_k127_2630493_3	1313172.YM304_01570	2.65e-135	450.0	COG0402@1|root,COG0402@2|Bacteria,2ISY0@201174|Actinobacteria	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158347_k127_2630493_0	1313172.YM304_01560	1.666e-191	626.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	MA20_01050	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
SRR25158347_k127_2630493_9	1043493.BBLU01000014_gene1348	6.734e-38	158.0	2F548@1|root,33XRC@2|Bacteria,2H5BG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2630493_2	397278.JOJN01000007_gene3432	1.576e-152	494.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,4DPAH@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2630493_8	164757.Mjls_0780	3.705e-39	168.0	COG1073@1|root,COG1073@2|Bacteria,2IASV@201174|Actinobacteria,2333V@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Peptidase_S9
SRR25158347_k127_2630493_5	1229780.BN381_70002	7.598e-116	411.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158347_k127_2630493_6	344747.PM8797T_18039	1.368e-97	334.0	COG0665@1|root,COG0665@2|Bacteria,2IXGH@203682|Planctomycetes	203682|Planctomycetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158347_k127_2630493_10	110319.CF8_2620	8.13e-29	123.0	COG1404@1|root,COG1404@2|Bacteria,2I8MD@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Malectin,Peptidase_S8,SLH,fn3_5
SRR25158347_k127_2639274_10	1150864.MILUP08_42352	5.472e-16	81.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria,4DBB2@85008|Micromonosporales	201174|Actinobacteria	EM	hydrolase, HAD-superfamily, subfamily IIIA	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
SRR25158347_k127_2639274_3	869210.Marky_1653	3.748e-72	263.0	COG2605@1|root,COG2605@2|Bacteria,1WKER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2605 kinase related to galactokinase and mevalonate kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158347_k127_2639274_2	298654.FraEuI1c_1807	6.479e-85	295.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4ERSX@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2639274_9	1298863.AUEP01000018_gene3838	3.944e-36	158.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,4DNFV@85009|Propionibacteriales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158347_k127_2639274_12	42374.XP_002419425.1	2.656e-07	63.0	KOG1546@1|root,KOG1546@2759|Eukaryota,38EI0@33154|Opisthokonta,3NW3X@4751|Fungi,3QKCB@4890|Ascomycota,3RS6R@4891|Saccharomycetes,47A7K@766764|Debaryomycetaceae	4751|Fungi	DO	Involved in cell death (apoptosis)	casA	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0006508,GO:0006807,GO:0006915,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0009056,GO:0009057,GO:0009987,GO:0012501,GO:0016787,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158347_k127_2639274_13	1056816.JAFQ01000004_gene4246	1.39e-05	57.0	COG2867@1|root,COG2867@2|Bacteria,2IIBS@201174|Actinobacteria,4G21F@85025|Nocardiaceae	201174|Actinobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2639274_1	397278.JOJN01000004_gene1185	7.762e-111	370.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4DPCJ@85009|Propionibacteriales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158347_k127_2639274_6	1210045.ALNP01000012_gene1516	6.319e-59	216.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158347_k127_2639274_4	264732.Moth_1948	5.194e-72	254.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,42FNN@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Aspartate glutamate uridylate kinase	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158347_k127_2639274_14	1274524.BSONL12_05588	5.385e-05	54.0	COG3568@1|root,COG3568@2|Bacteria,1V9H0@1239|Firmicutes,4HFXZ@91061|Bacilli,1ZG3C@1386|Bacillus	91061|Bacilli	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158347_k127_2639274_0	103733.JNYO01000013_gene4270	8.005e-203	663.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4DZ08@85010|Pseudonocardiales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR25158347_k127_2639274_5	298653.Franean1_1829	3.111e-70	248.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4ERMB@85013|Frankiales	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_2639274_7	861208.AGROH133_04721	3.376e-53	193.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,4BEGJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158347_k127_2639274_8	1232410.KI421418_gene2303	1.943e-38	157.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NWG@68525|delta/epsilon subdivisions,2WKEU@28221|Deltaproteobacteria,43VRR@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
SRR25158347_k127_2639274_11	1151126.AQYI01000006_gene3440	1.714e-11	74.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FNJ1@85023|Microbacteriaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158347_k127_2659418_0	1089455.MOPEL_074_00560	1.025e-198	623.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4F6CC@85018|Dermatophilaceae	201174|Actinobacteria	O	Bacterial TniB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158347_k127_2659418_2	1214101.BN159_3642	4.169e-48	186.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158347_k127_2659418_3	357808.RoseRS_3285	2.483e-40	158.0	COG1611@1|root,COG1611@2|Bacteria,2G6P1@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158347_k127_2659418_1	1123368.AUIS01000016_gene2528	1.958e-149	490.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,2NC0Y@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158347_k127_2659887_10	1485543.JMME01000002_gene1697	2.785e-37	147.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_2659887_13	1121946.AUAX01000004_gene706	2.907e-19	95.0	29RUC@1|root,30CY9@2|Bacteria,2GW9D@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158347_k127_2659887_4	882086.SacxiDRAFT_3363	1.941e-91	326.0	COG1543@1|root,COG1543@2|Bacteria,2GKTI@201174|Actinobacteria,4DZYG@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158347_k127_2659887_9	1429046.RR21198_3181	5.751e-71	249.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4FVHI@85025|Nocardiaceae	201174|Actinobacteria	H	Methyltransferase domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158347_k127_2659887_7	269800.Tfu_0593	4.274e-77	267.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4EFT7@85012|Streptosporangiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158347_k127_2659887_3	471852.Tcur_3574	3.248e-93	316.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4EGI3@85012|Streptosporangiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158347_k127_2659887_14	1379698.RBG1_1C00001G0785	1.452e-11	77.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158347_k127_2659887_5	861299.J421_2864	4.71e-81	296.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
SRR25158347_k127_2659887_6	1122602.ATXP01000001_gene1036	1.566e-80	283.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,1W8C2@1268|Micrococcaceae	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158347_k127_2659887_2	105420.BBPO01000030_gene6670	3.439e-105	353.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,2NHR7@228398|Streptacidiphilus	201174|Actinobacteria	J	tRNA methyl transferase	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158347_k127_2659887_0	298653.Franean1_1082	5.407e-203	655.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4ES5B@85013|Frankiales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158347_k127_2659887_8	1206735.BAGG01000027_gene1213	2.324e-72	250.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4FUW7@85025|Nocardiaceae	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158347_k127_2659887_1	1121017.AUFG01000055_gene28	1.025e-143	469.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4FFB9@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158347_k127_2659887_12	479434.Sthe_1075	8.652e-24	106.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi,27ZAC@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158347_k127_2659887_11	1123251.ATWM01000003_gene1164	7.349e-26	109.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4FH6M@85021|Intrasporangiaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158347_k127_2679468_3	911045.PSE_1468	1.431e-80	273.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158347_k127_2679468_1	1120936.KB907210_gene5636	3.351e-170	552.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4EGQY@85012|Streptosporangiales	201174|Actinobacteria	J	Ribosomal protein S1-like RNA-binding domain	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158347_k127_2679468_5	1111729.ATYV01000023_gene1471	2.675e-53	195.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,22MZB@1653|Corynebacteriaceae	201174|Actinobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158347_k127_2679468_7	1408254.T458_13600	1.976e-15	90.0	COG0308@1|root,COG0308@2|Bacteria,1U6PC@1239|Firmicutes,4HD74@91061|Bacilli,26R17@186822|Paenibacillaceae	91061|Bacilli	E	EnpEP protein	pepN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158347_k127_2679468_0	365528.KB891219_gene1036	4.377e-282	889.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4ERJA@85013|Frankiales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158347_k127_2679468_10	1071073.KI530541_gene3316	8.218e-05	57.0	COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus	91061|Bacilli	V	Belongs to the UPF0214 family	estB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Peptidase_M6
SRR25158347_k127_2679468_6	290397.Adeh_3524	1.636e-49	205.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
SRR25158347_k127_2679468_2	1121019.AUMN01000005_gene2714	2.171e-116	386.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_2679468_4	68170.KL590533_gene5260	4.098e-76	269.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4E1XJ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158347_k127_2679468_9	1123065.ATWL01000020_gene3528	2.907e-10	72.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158347_k127_2713430_0	471852.Tcur_3512	2.545e-126	426.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria,4EMIB@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_2713430_4	1123256.KB907925_gene1469	2.87e-81	280.0	COG1028@1|root,COG1028@2|Bacteria,1P1U4@1224|Proteobacteria,1RR3M@1236|Gammaproteobacteria,1X52M@135614|Xanthomonadales	135614|Xanthomonadales	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_2713430_2	58123.JOFJ01000013_gene4895	2.916e-100	342.0	COG1024@1|root,COG1024@2|Bacteria,2GN54@201174|Actinobacteria,4EIAR@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA20	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_2713430_1	1323361.JPOC01000066_gene94	5.212e-124	403.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4FZIK@85025|Nocardiaceae	201174|Actinobacteria	I	Coenzyme A transferase	cotA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158347_k127_2713430_3	935866.JAER01000002_gene1947	4.828e-85	295.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DNCU@85009|Propionibacteriales	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRR25158347_k127_2713430_5	443218.AS9A_0955	2.928e-37	154.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,2340X@1762|Mycobacteriaceae	201174|Actinobacteria	S	2-nitropropane dioxygenase	fabK	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158347_k127_2715603_27	1048339.KB913029_gene1536	9.507e-12	78.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2715603_19	1313172.YM304_26180	4.224e-46	173.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158347_k127_2715603_16	1157640.AQWO01000016_gene959	1.944e-65	246.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_2715603_22	526225.Gobs_5078	2.728e-34	141.0	COG5549@1|root,COG5549@2|Bacteria,2IPD4@201174|Actinobacteria	201174|Actinobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SRR25158347_k127_2715603_25	272563.CD630_20120	3.784e-17	93.0	COG2267@1|root,COG2267@2|Bacteria,1UIMD@1239|Firmicutes,25EXC@186801|Clostridia	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_2715603_6	1169161.KB897716_gene5997	2.541e-168	555.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158347_k127_2715603_18	479435.Kfla_6871	1.714e-58	211.0	COG1028@1|root,COG1028@2|Bacteria,2IP6B@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_2715603_9	197221.22293770	3.153e-105	369.0	COG0744@1|root,COG0744@2|Bacteria,1G1XF@1117|Cyanobacteria	1117|Cyanobacteria	M	Penicillin-binding protein, 1A family	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_2715603_3	471852.Tcur_0271	4.075e-197	634.0	COG1960@1|root,COG1960@2|Bacteria,2GJIB@201174|Actinobacteria,4EFZX@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRR25158347_k127_2715603_28	1048339.KB913029_gene3242	6.56e-08	61.0	COG1309@1|root,COG1309@2|Bacteria,2HE48@201174|Actinobacteria,4ET8R@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2715603_11	1089544.KB912942_gene2104	3.548e-99	339.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4E14W@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158347_k127_2715603_13	1313172.YM304_21470	3.079e-95	330.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CN10@84992|Acidimicrobiia	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158347_k127_2715603_26	502025.Hoch_5209	1.151e-14	83.0	2E6D6@1|root,3310T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2715603_21	1313172.YM304_14800	2.536e-35	145.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_2715603_14	1193181.BN10_1020002	9.364e-72	257.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4FFAT@85021|Intrasporangiaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158347_k127_2715603_8	40571.JOEA01000030_gene5722	2.374e-106	353.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4DX4N@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_2715603_20	1445613.JALM01000010_gene2414	4.326e-40	154.0	COG3631@1|root,COG3631@2|Bacteria,2IG87@201174|Actinobacteria,4E3F5@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
SRR25158347_k127_2715603_0	1172179.AUKV01000005_gene5724	1.62e-243	763.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria	201174|Actinobacteria	EG	Belongs to the ILVD EDD family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158347_k127_2715603_23	1122939.ATUD01000005_gene2610	4.27e-30	138.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4CPXS@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_2715603_24	644283.Micau_2398	1.457e-29	129.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4DE1B@85008|Micromonosporales	201174|Actinobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_2715603_10	298655.KI912266_gene2496	3.156e-105	359.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_2715603_7	446468.Ndas_2836	2.952e-158	509.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EHSE@85012|Streptosporangiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_2715603_5	706587.Desti_2952	3.435e-183	602.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MR0I@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158347_k127_2715603_2	65497.JODV01000013_gene2296	1.174e-207	704.0	COG1012@1|root,COG1012@2|Bacteria,2GJZE@201174|Actinobacteria,4DX9P@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Aldehyde dehydrogenase	putA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158347_k127_2715603_15	1298863.AUEP01000008_gene1321	2.733e-71	269.0	COG2197@1|root,COG3829@1|root,COG2197@2|Bacteria,COG3829@2|Bacteria,2IDZS@201174|Actinobacteria	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,Response_reg
SRR25158347_k127_2715603_4	1229780.BN381_210057	1.549e-188	604.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2715603_12	196162.Noca_2748	1.482e-98	338.0	COG0613@1|root,COG0613@2|Bacteria,2IDTP@201174|Actinobacteria	201174|Actinobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
SRR25158347_k127_2715603_17	483219.LILAB_13505	1.092e-62	244.0	COG1024@1|root,COG1024@2|Bacteria,1R67S@1224|Proteobacteria,430BK@68525|delta/epsilon subdivisions,2WVNK@28221|Deltaproteobacteria,2YY2F@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_2715603_1	479435.Kfla_6020	4.386e-216	684.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4DNRG@85009|Propionibacteriales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158347_k127_2722592_7	1211114.ALIP01000114_gene1465	1.521e-35	152.0	COG1365@1|root,COG1365@2|Bacteria,1R62V@1224|Proteobacteria,1S2JY@1236|Gammaproteobacteria,1X5D9@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2722592_9	298655.KI912266_gene3772	4.312e-28	121.0	COG0526@1|root,COG0526@2|Bacteria,2IR6C@201174|Actinobacteria,4EWWC@85013|Frankiales	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158347_k127_2722592_6	448385.sce2873	1.807e-37	153.0	COG1011@1|root,COG1011@2|Bacteria,1Q2A3@1224|Proteobacteria,437WW@68525|delta/epsilon subdivisions,2X36I@28221|Deltaproteobacteria,2YWJT@29|Myxococcales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158347_k127_2722592_8	258052.JNYV01000002_gene1841	8.157e-32	132.0	COG1714@1|root,COG1714@2|Bacteria,2GS9U@201174|Actinobacteria	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158347_k127_2722592_2	644283.Micau_5090	3.679e-125	409.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4DBEM@85008|Micromonosporales	201174|Actinobacteria	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158347_k127_2722592_3	222534.KB893794_gene2466	2.398e-116	382.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4EX6N@85013|Frankiales	201174|Actinobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158347_k127_2722592_4	1347369.CCAD010000035_gene1038	2.812e-70	249.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,4HI9S@91061|Bacilli,1ZF15@1386|Bacillus	91061|Bacilli	I	Steryl acetyl hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158347_k127_2722592_5	1160718.SU9_20484	5.494e-70	263.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158347_k127_2722592_10	869210.Marky_1382	1.038e-25	108.0	COG3360@1|root,COG3360@2|Bacteria,1WKKK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158347_k127_2722592_1	222534.KB893794_gene2469	2.549e-170	553.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4ERX1@85013|Frankiales	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158347_k127_2722592_0	391037.Sare_0154	2.086e-197	623.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4DBUB@85008|Micromonosporales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158347_k127_2729845_2	1137271.AZUM01000004_gene3989	2.897e-142	465.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DXC8@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158347_k127_2729845_15	263358.VAB18032_11910	2.446e-25	118.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria,4DD92@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158347_k127_2729845_10	1206731.BAGB01000166_gene860	2.128e-46	181.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,4G0V4@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_2729845_1	1179773.BN6_78790	1.234e-199	639.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4DZ05@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158347_k127_2729845_7	290397.Adeh_1502	1.317e-59	234.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2YURF@29|Myxococcales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158347_k127_2729845_5	1229780.BN381_130029	2.85e-84	299.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,3UWJZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158347_k127_2729845_4	1128421.JAGA01000001_gene2118	1.083e-95	337.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
SRR25158347_k127_2729845_8	477184.KYC_24392	9.452e-57	216.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria	28216|Betaproteobacteria	EQ	PFAM peptidase S58, DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158347_k127_2729845_12	1217718.ALOU01000041_gene74	9.792e-37	149.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,1K1QM@119060|Burkholderiaceae	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158347_k127_2729845_14	696369.KI912183_gene2681	1.185e-28	126.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158347_k127_2729845_9	1229780.BN381_130031	9.226e-51	194.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,3UWTU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158347_k127_2729845_16	471853.Bcav_3070	3.009e-20	101.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria	201174|Actinobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158347_k127_2729845_3	356851.JOAN01000013_gene5862	9.994e-109	362.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4D9ZK@85008|Micromonosporales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158347_k127_2729845_17	1206743.BAGM01000093_gene4583	6.414e-15	85.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4FU66@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158347_k127_2729845_13	266940.Krad_3007	3.29e-35	147.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158347_k127_2729845_11	1041522.MCOL_V216229	1.149e-38	148.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,23A39@1762|Mycobacteriaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158347_k127_2729845_0	1120950.KB892775_gene1166	1.06e-247	774.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNNQ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158347_k127_2729845_18	350054.Mflv_4913	5.767e-06	57.0	2F0NR@1|root,33TR6@2|Bacteria,2GUJF@201174|Actinobacteria,233QX@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2729845_6	266265.Bxe_C0596	2.417e-82	289.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VGZU@28216|Betaproteobacteria,1K0VY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158347_k127_274870_1	383372.Rcas_3504	1.53e-159	513.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi,375DB@32061|Chloroflexia	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_274870_2	525904.Tter_2442	4.613e-97	331.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158347_k127_274870_3	443255.SCLAV_5624	2.241e-54	202.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158347_k127_274870_4	1206101.AZXC01000001_gene4747	5.556e-17	94.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158347_k127_274870_0	1278078.G419_15422	2.705e-320	1000.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4FVPP@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_274870_6	593907.Celgi_1030	0.0005947	51.0	COG3797@1|root,COG3797@2|Bacteria,2HR3U@201174|Actinobacteria,4F1HR@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158347_k127_2777702_2	1229780.BN381_100072	1.455e-71	251.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158347_k127_2777702_0	66874.JOFS01000049_gene3200	3.077e-236	773.0	2AQV1@1|root,31G37@2|Bacteria,2IEU1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158347_k127_2777702_1	196162.Noca_1788	2.502e-110	392.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4DTHI@85009|Propionibacteriales	201174|Actinobacteria	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158347_k127_2777702_3	1211815.CBYP010000069_gene1398	3.576e-69	241.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,4ESD2@85013|Frankiales	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158347_k127_2777702_4	1415166.NONO_c25060	7.611e-06	51.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4FWNE@85025|Nocardiaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158347_k127_2781776_15	1313172.YM304_31100	7.451e-18	85.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158347_k127_2781776_4	1283300.ATXB01000001_gene513	4.311e-69	241.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria,1XEH3@135618|Methylococcales	135618|Methylococcales	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158347_k127_2781776_10	1306174.JODP01000016_gene7208	2.101e-48	192.0	COG1432@1|root,COG1432@2|Bacteria,2GMV5@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	ko:K06860	-	-	-	-	ko00000	-	-	-	NYN
SRR25158347_k127_2781776_9	710696.Intca_0275	1.495e-52	212.0	COG2247@1|root,COG2247@2|Bacteria,2I4K0@201174|Actinobacteria,4FGIA@85021|Intrasporangiaceae	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,VCBS
SRR25158347_k127_2781776_0	926550.CLDAP_10980	8.756e-201	635.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.1,4.1.99.2	ko:K01667,ko:K01668	ko00350,ko00380,map00350,map00380	-	R00673,R00728	RC00209,RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158347_k127_2781776_8	1137271.AZUM01000001_gene1168	4.392e-53	191.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4E31I@85010|Pseudonocardiales	201174|Actinobacteria	O	Redoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158347_k127_2781776_11	1108045.GORHZ_118_00840	1.145e-42	163.0	COG1309@1|root,COG1309@2|Bacteria,2IMHK@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2781776_6	1123258.AQXZ01000019_gene3135	1.276e-56	214.0	2A651@1|root,30UXH@2|Bacteria,2IERM@201174|Actinobacteria,4G38Y@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158347_k127_2781776_2	58123.JOFJ01000027_gene2789	1.519e-110	370.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4EFPC@85012|Streptosporangiales	201174|Actinobacteria	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158347_k127_2781776_5	1170318.PALO_03325	2.544e-61	235.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DNDT@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158347_k127_2781776_1	526225.Gobs_0929	1.592e-191	604.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4ES7N@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA2	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_2781776_17	1289387.AUKW01000004_gene1503	6.183e-07	58.0	2F2DM@1|root,305YS@2|Bacteria,2IRT1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2781776_12	1123024.AUII01000009_gene1973	3.815e-39	150.0	2E2XX@1|root,32XYT@2|Bacteria,2IK9M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2781776_14	67275.JOAP01000005_gene5930	1.535e-25	115.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_2781776_13	1274.HX89_11075	7.807e-39	153.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,1ZVWG@145357|Dermacoccaceae	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158347_k127_2781776_3	1449976.KALB_876	6.126e-90	303.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4DYMM@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS1	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158347_k127_2781776_7	1122138.AQUZ01000012_gene6001	2.249e-54	205.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4DPTR@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158347_k127_2781776_16	479434.Sthe_0750	6.226e-16	83.0	COG5002@1|root,COG5002@2|Bacteria,2G6F5@200795|Chloroflexi,27Z71@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_2798857_0	1157632.AQWQ01000016_gene3365	1.424e-97	334.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158347_k127_2798857_3	1463934.JOCF01000073_gene5857	1.827e-38	156.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Acyl transferase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158347_k127_2798857_2	195250.CM001776_gene2017	1.931e-52	205.0	COG1028@1|root,COG1028@2|Bacteria,1G0MD@1117|Cyanobacteria,1GYGM@1129|Synechococcus	1117|Cyanobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_2798857_11	762376.AXYL_01370	4.976e-12	78.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,2VTBF@28216|Betaproteobacteria,3T6K4@506|Alcaligenaceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_2798857_10	234267.Acid_7195	6.214e-13	82.0	28JQV@1|root,2Z7R2@2|Bacteria,3Y619@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2798857_1	1150864.MILUP08_43560	2.631e-84	314.0	COG0318@1|root,COG0318@2|Bacteria,2GNIW@201174|Actinobacteria,4D8TC@85008|Micromonosporales	201174|Actinobacteria	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158347_k127_2798857_6	443255.SCLAV_2604	3.883e-23	109.0	COG2091@1|root,COG2091@2|Bacteria,2IQ65@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158347_k127_2798857_8	1382306.JNIM01000001_gene3919	2.43e-21	103.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_2798857_9	1190606.AJYG01000057_gene3885	7.656e-15	89.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,1T1XV@1236|Gammaproteobacteria,1XUBC@135623|Vibrionales	135623|Vibrionales	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
SRR25158347_k127_2798857_5	68260.JOAY01000005_gene4899	6.15e-24	110.0	COG2197@1|root,COG2197@2|Bacteria,2GJG4@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_2798857_12	1463861.JNXE01000016_gene7520	7.269e-12	77.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_2798857_7	82654.Pse7367_3705	1.165e-21	98.0	COG1396@1|root,COG1396@2|Bacteria,1GICH@1117|Cyanobacteria,1HGFR@1150|Oscillatoriales	1117|Cyanobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2798857_4	43354.JOIJ01000001_gene121	1.669e-32	140.0	COG2856@1|root,COG2856@2|Bacteria,2IK1U@201174|Actinobacteria,4E3HE@85010|Pseudonocardiales	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158347_k127_2814_9	1501230.ET33_11255	3.671e-10	71.0	COG0454@1|root,COG0456@2|Bacteria,1VC3M@1239|Firmicutes,4IS49@91061|Bacilli,26WSP@186822|Paenibacillaceae	91061|Bacilli	K	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158347_k127_2814_8	68170.KL590492_gene6165	2.1e-19	93.0	2BNCR@1|root,32H0E@2|Bacteria,2HRIE@201174|Actinobacteria,4EASX@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158347_k127_2814_4	2002.JOEQ01000005_gene3526	1.02e-66	233.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4EJ8Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2814_5	471857.Svir_38980	2.317e-47	179.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria,4E5TR@85010|Pseudonocardiales	201174|Actinobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_IclR
SRR25158347_k127_2814_6	1394178.AWOO02000021_gene7351	1.731e-36	158.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria,4EFHA@85012|Streptosporangiales	201174|Actinobacteria	PQ	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158347_k127_2814_1	1123024.AUII01000024_gene247	2.255e-84	287.0	COG4309@1|root,COG4309@2|Bacteria,2GS7C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
SRR25158347_k127_2814_0	298655.KI912266_gene3883	7.892e-104	351.0	COG0438@1|root,COG0438@2|Bacteria,2GNPG@201174|Actinobacteria,4ETRT@85013|Frankiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2814_2	710696.Intca_3046	3.738e-84	291.0	COG1105@1|root,COG1105@2|Bacteria	2|Bacteria	H	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158347_k127_2814_3	345341.KUTG_02431	2.521e-67	254.0	COG2152@1|root,COG2152@2|Bacteria,2HNS8@201174|Actinobacteria,4EA2Q@85010|Pseudonocardiales	201174|Actinobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158347_k127_2819843_6	469383.Cwoe_2359	1.826e-11	65.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPTB@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_2819843_0	935866.JAER01000023_gene2288	1.968e-190	601.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4DPZ9@85009|Propionibacteriales	201174|Actinobacteria	I	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
SRR25158347_k127_2819843_5	258533.BN977_01168	5.402e-37	152.0	COG1545@1|root,COG1545@2|Bacteria,2IFQP@201174|Actinobacteria,238SF@1762|Mycobacteriaceae	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158347_k127_2819843_3	1229780.BN381_130179	2.658e-65	235.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_2819843_1	1240350.AMZE01000075_gene4391	2.343e-162	540.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2819843_4	247634.GPB2148_2815	3.811e-64	234.0	COG1960@1|root,COG1960@2|Bacteria,1P4V3@1224|Proteobacteria,1RZBS@1236|Gammaproteobacteria,1J4FZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158347_k127_2819843_2	935839.JAGJ01000006_gene3451	1.385e-71	248.0	COG3154@1|root,COG3154@2|Bacteria	2|Bacteria	-	-	yhbT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	MDMPI_C,MDMPI_N,SCP2
SRR25158347_k127_2847379_0	349521.HCH_04995	1.868e-240	760.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1XMDW@135619|Oceanospirillales	135619|Oceanospirillales	M	dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
SRR25158347_k127_2847379_1	1247963.JPHU01000003_gene1302	3.987e-119	389.0	COG1075@1|root,COG1075@2|Bacteria,1NS75@1224|Proteobacteria	1224|Proteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2855638_13	1038862.KB893833_gene4737	5.752e-19	87.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TT8N@28211|Alphaproteobacteria,3JSX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	MA20_42585	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158347_k127_2855638_0	469371.Tbis_3135	8.11e-320	1017.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DXZU@85010|Pseudonocardiales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158347_k127_2855638_8	215803.DB30_5033	2.425e-54	198.0	COG1309@1|root,COG1309@2|Bacteria,1N8UC@1224|Proteobacteria,43DN7@68525|delta/epsilon subdivisions,2X291@28221|Deltaproteobacteria,2YYN1@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2855638_3	1453500.AT05_11510	8.423e-98	327.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,1HX0M@117743|Flavobacteriia	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158347_k127_2855638_10	1169161.KB897723_gene4700	5.792e-45	172.0	2AUFS@1|root,31K3Y@2|Bacteria,2GIXC@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4191
SRR25158347_k127_2855638_7	743718.Isova_2501	1.353e-59	212.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4F3IZ@85017|Promicromonosporaceae	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158347_k127_2855638_12	1123488.ATUF01000003_gene1157	1.882e-33	138.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4D4B1@85005|Actinomycetales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158347_k127_2855638_11	471853.Bcav_4054	1.393e-36	148.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158347_k127_2855638_2	1120954.ATXE01000001_gene2187	2.629e-113	374.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4DP73@85009|Propionibacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158347_k127_2855638_1	1121428.DESHY_40157___1	1.115e-132	439.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SRR25158347_k127_2855638_5	743718.Isova_2515	3.705e-64	232.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4F3UP@85017|Promicromonosporaceae	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158347_k127_2855638_6	706439.HMPREF9057_01167	2.452e-61	230.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4D3QK@85005|Actinomycetales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158347_k127_2855638_9	1380347.JNII01000006_gene1427	8.639e-53	201.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4ESFI@85013|Frankiales	201174|Actinobacteria	M	Transglycosylase domain protein	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158347_k127_2855638_4	1169161.KB897724_gene4938	1.006e-69	246.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria	201174|Actinobacteria	L	Hydrolase, TatD family	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158347_k127_2871684_16	1313172.YM304_22540	2.415e-16	89.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	lytH	-	-	ko:K06401,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	DUF3289,Peptidase_M23,SH3_3
SRR25158347_k127_2871684_0	103733.JNYO01000029_gene804	7.145e-293	915.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,4DZXB@85010|Pseudonocardiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158347_k127_2871684_13	502025.Hoch_4661	6.504e-48	182.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria,434JF@68525|delta/epsilon subdivisions,2WYWP@28221|Deltaproteobacteria,2Z0TD@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158347_k127_2871684_3	219305.MCAG_03752	1.017e-140	459.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DB0R@85008|Micromonosporales	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158347_k127_2871684_2	867903.ThesuDRAFT_01213	2.248e-152	498.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,25F3I@186801|Clostridia,3WCCI@538999|Clostridiales incertae sedis	186801|Clostridia	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158347_k127_2871684_6	222534.KB893739_gene1489	2.706e-106	377.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4ERG2@85013|Frankiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158347_k127_2871684_14	1449048.JQKU01000007_gene124	5.57e-42	156.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,2397Y@1762|Mycobacteriaceae	201174|Actinobacteria	K	nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158347_k127_2871684_5	28444.JODQ01000002_gene4256	5.376e-114	386.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4EGE3@85012|Streptosporangiales	201174|Actinobacteria	FL	AlkA N-terminal domain	alkA	-	3.2.2.21	ko:K01247,ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158347_k127_2871684_15	1121124.JNIX01000011_gene1884	7.049e-38	151.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,2KGW8@204458|Caulobacterales	204458|Caulobacterales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158347_k127_2871684_8	391625.PPSIR1_20549	1.034e-86	291.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,42Q1Z@68525|delta/epsilon subdivisions,2WM01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158347_k127_2871684_7	469383.Cwoe_5544	1.541e-95	321.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158347_k127_2871684_4	450380.JPSY01000001_gene560	2.304e-116	387.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4FM6N@85023|Microbacteriaceae	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158347_k127_2871684_12	1343740.M271_28390	1.062e-57	204.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158347_k127_2871684_9	1157637.KB892146_gene7066	1.288e-85	302.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,2GNP7@201174|Actinobacteria	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Biotin_carb_N,Carboxyl_trans
SRR25158347_k127_2871684_11	235985.BBPN01000033_gene11	8.504e-79	277.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,2NH2E@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_2871684_1	868595.Desca_1738	8.226e-220	706.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158347_k127_2871684_10	1211815.CBYP010000053_gene2085	4.884e-84	292.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158347_k127_2903766_0	1002340.AFCF01000020_gene1432	3.592e-80	276.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,34DWY@302485|Phaeobacter	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	aldH	-	1.2.1.99	ko:K09472	ko00330,ko01100,map00330,map01100	M00136	R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_2903766_1	1122182.KB903837_gene3780	4.365e-55	216.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DF2R@85008|Micromonosporales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_2903766_2	426716.JOAJ01000009_gene5906	6.689e-22	102.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4FX8K@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_2924133_0	42256.RradSPS_0499	1.746e-145	484.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4CRH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158347_k127_2924133_1	585531.HMPREF0063_12202	1.803e-134	439.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4DPCG@85009|Propionibacteriales	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158347_k127_2939249_5	1122611.KB903948_gene6718	3.102e-31	133.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158347_k127_2939249_4	1157632.AQWQ01000017_gene3232	1.93e-33	151.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158347_k127_2939249_1	1122611.KB903948_gene6716	7.583e-115	383.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria,4EGJX@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158347_k127_2939249_3	134676.ACPL_2577	1.382e-80	285.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4D9QK@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_2939249_6	106370.Francci3_4318	3.096e-17	92.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4ESRA@85013|Frankiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158347_k127_2939249_7	525257.HMPREF0204_11738	8.838e-10	71.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia,3ZS92@59732|Chryseobacterium	976|Bacteroidetes	T	Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
SRR25158347_k127_2939249_8	1095767.CAHD01000200_gene2361	7.211e-06	52.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158347_k127_2939249_2	1229780.BN381_90064	3.009e-107	357.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,3UX2T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Molybdenum Cofactor Synthesis C	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158347_k127_2939249_0	314278.NB231_09548	2.809e-135	447.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
SRR25158347_k127_2939249_9	1206101.AZXC01000006_gene3865	8.055e-05	49.0	COG0596@1|root,COG0596@2|Bacteria,2IJXZ@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_296724_6	525368.HMPREF0591_2100	1.146e-22	104.0	COG2251@1|root,COG2251@2|Bacteria,2HF5B@201174|Actinobacteria,2359V@1762|Mycobacteriaceae	201174|Actinobacteria	S	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H_2
SRR25158347_k127_296724_4	479434.Sthe_1853	2.1e-44	181.0	COG0699@1|root,COG1061@1|root,COG1112@1|root,COG0699@2|Bacteria,COG1061@2|Bacteria,COG1112@2|Bacteria,2G5NB@200795|Chloroflexi,27Z3U@189775|Thermomicrobia	189775|Thermomicrobia	KL	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
SRR25158347_k127_296724_1	211114.JOEF01000004_gene6618	8.595e-71	246.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E1KK@85010|Pseudonocardiales	201174|Actinobacteria	KT	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_296724_5	1380347.JNII01000008_gene4341	9.559e-39	167.0	COG4585@1|root,COG4585@2|Bacteria,2GM7E@201174|Actinobacteria,4EVJI@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_296724_9	1122222.AXWR01000019_gene2664	0.0001256	55.0	COG1404@1|root,COG1404@2|Bacteria,1WMNE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
SRR25158347_k127_296724_8	471853.Bcav_4068	3.271e-19	89.0	2DF58@1|root,2ZQII@2|Bacteria,2H0N5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_296724_3	875328.JDM601_3263	6.489e-53	192.0	COG1848@1|root,COG1848@2|Bacteria,2IK8U@201174|Actinobacteria,2396G@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158347_k127_296724_2	222534.KB893672_gene2971	3.389e-62	220.0	COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_296724_0	1120960.ATXG01000015_gene1565	2.356e-108	368.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SRR25158347_k127_296724_7	287986.DV20_42845	2.065e-19	96.0	COG2867@1|root,COG2867@2|Bacteria,2IEZI@201174|Actinobacteria	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_2991896_25	395963.Bind_1030	3.016e-28	118.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,3NB6G@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	Polynucleotide kinase 3 phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_6,Hydrolase_like,NTP_transferase,PRK
SRR25158347_k127_2991896_19	35754.JNYJ01000025_gene8877	5.515e-45	170.0	COG0279@1|root,COG0279@2|Bacteria,2IIGW@201174|Actinobacteria,4DCS3@85008|Micromonosporales	201174|Actinobacteria	G	Phosphoheptose isomerase	gmhA	-	2.7.7.71,5.3.1.28	ko:K03271,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769,R09772	RC00002,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158347_k127_2991896_20	1121272.KB903252_gene1167	9.371e-45	183.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,4D8ZH@85008|Micromonosporales	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158347_k127_2991896_38	767029.HMPREF9154_1533	7.199e-12	77.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4DR1M@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
SRR25158347_k127_2991896_28	675635.Psed_2762	8.704e-23	111.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria,4DZ65@85010|Pseudonocardiales	201174|Actinobacteria	S	RNA-binding protein containing a PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158347_k127_2991896_37	196162.Noca_3127	6.637e-15	87.0	2ES7R@1|root,33JSG@2|Bacteria,2IQ6C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2991896_30	875328.JDM601_0565	1.569e-18	97.0	COG1547@1|root,COG1547@2|Bacteria,2IHUS@201174|Actinobacteria,239A2@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158347_k127_2991896_12	1229780.BN381_90081	9.466e-76	263.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,3UWHS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158347_k127_2991896_29	1394178.AWOO02000016_gene6908	1.809e-21	109.0	COG1309@1|root,COG1309@2|Bacteria,2IPSV@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2991896_34	1068978.AMETH_5107	5.244e-16	81.0	2CC1Y@1|root,30UIS@2|Bacteria,2GRYX@201174|Actinobacteria,4ECN7@85010|Pseudonocardiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158347_k127_2991896_4	479435.Kfla_2797	3.885e-144	477.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,4DNVQ@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III, epsilon subunit	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158347_k127_2991896_21	1123256.KB907928_gene1940	1.856e-38	151.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,1S6NH@1236|Gammaproteobacteria,1X7AS@135614|Xanthomonadales	135614|Xanthomonadales	J	Putative tRNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_bind
SRR25158347_k127_2991896_9	1128421.JAGA01000002_gene245	1.658e-93	318.0	COG0547@1|root,COG0547@2|Bacteria,2NNVH@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0004048,GO:0004049,GO:0004425,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495,iJN746.PP_0421,iSBO_1134.SBO_1803,iSbBS512_1146.SbBS512_E1488,iYL1228.KPN_01256	GATase,Glycos_trans_3N,Glycos_transf_3
SRR25158347_k127_2991896_26	584708.Apau_2248	6.569e-27	121.0	COG0745@1|root,COG0745@2|Bacteria,3TAJR@508458|Synergistetes	508458|Synergistetes	K	PFAM response regulator receiver	-	-	-	ko:K07657,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2991896_35	1160137.KB907307_gene1305	8.973e-16	82.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4G19C@85025|Nocardiaceae	201174|Actinobacteria	T	cheY-homologous receiver domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_2991896_43	1042377.AFPJ01000052_gene1546	9.604e-09	70.0	COG1404@1|root,COG4886@1|root,COG4932@1|root,COG5184@1|root,COG1404@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,1QY9I@1224|Proteobacteria,1T3MN@1236|Gammaproteobacteria,46D5E@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2991896_14	644966.Tmar_1229	7.134e-70	252.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WCZD@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158347_k127_2991896_36	1961.JOAK01000017_gene708	4.511e-15	78.0	COG1104@1|root,COG1104@2|Bacteria,2GJ2B@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the sulfur carrier protein TusA family	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,TusA
SRR25158347_k127_2991896_23	931627.MycrhDRAFT_4075	1.268e-31	138.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,2398Y@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158347_k127_2991896_16	1454010.JEOE01000002_gene431	6.366e-57	225.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4F2HT@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158347_k127_2991896_1	1122609.AUGT01000022_gene752	5.018e-167	542.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4DNNM@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158347_k127_2991896_24	1449058.JQKT01000009_gene191	9.987e-30	136.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_2991896_18	1146883.BLASA_1057	1.946e-52	201.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EVZ3@85013|Frankiales	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_2991896_31	479433.Caci_8843	7.054e-18	98.0	COG0823@1|root,COG2247@1|root,COG0823@2|Bacteria,COG2247@2|Bacteria,2IDJU@201174|Actinobacteria	201174|Actinobacteria	U	Putative cell wall binding repeat 2	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CW_binding_2,PD40
SRR25158347_k127_2991896_39	351607.Acel_1209	4.313e-10	72.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158347_k127_2991896_10	350054.Mflv_2939	7.223e-93	319.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,235CE@1762|Mycobacteriaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158347_k127_2991896_46	680646.RMDY18_07270	6.031e-07	61.0	KOG1041@1|root,33PFT@2|Bacteria,2IGZ6@201174|Actinobacteria	201174|Actinobacteria	S	gene silencing by RNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2991896_2	1394178.AWOO02000084_gene1152	1.315e-152	503.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4EH93@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_2991896_6	526225.Gobs_3361	1.18e-112	380.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4ERCG@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E2 component	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158347_k127_2991896_17	326427.Cagg_1130	2.53e-53	204.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158347_k127_2991896_8	471852.Tcur_3099	3.018e-102	346.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4EHZS@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158347_k127_2991896_15	269800.Tfu_2998	3.802e-67	237.0	COG3154@1|root,COG3154@2|Bacteria,2I2XN@201174|Actinobacteria	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158347_k127_2991896_32	1449976.KALB_1025	9.62e-18	90.0	COG4270@1|root,COG4270@2|Bacteria,2IQJ5@201174|Actinobacteria,4E5T6@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158347_k127_2991896_11	1313172.YM304_22030	1.994e-79	277.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158347_k127_2991896_0	479432.Sros_2629	3.687e-226	711.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4EFP6@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamine synthetase, beta-Grasp domain	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158347_k127_2991896_27	561175.KB894093_gene2960	3.653e-24	115.0	2E384@1|root,32Y7U@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K18546	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin
SRR25158347_k127_2991896_45	1033730.CAHG01000016_gene262	4.942e-08	60.0	2B97S@1|root,322IY@2|Bacteria,2H6YD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2991896_42	1122182.KB903813_gene2594	8.308e-09	66.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
SRR25158347_k127_2991896_40	1122182.KB903813_gene2594	1.722e-09	66.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
SRR25158347_k127_2991896_5	1157637.KB892144_gene2581	2.694e-117	389.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158347_k127_2991896_33	105420.BBPO01000037_gene307	4.779e-17	86.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158347_k127_2991896_44	1032480.MLP_18570	2.99e-08	62.0	COG3311@1|root,COG3311@2|Bacteria,2HUV7@201174|Actinobacteria,4DSK5@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158347_k127_2991896_3	1380390.JIAT01000010_gene4387	6.435e-150	514.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158347_k127_2991896_13	1283283.ATXA01000047_gene4040	1.453e-70	247.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
SRR25158347_k127_2991896_22	216594.MMAR_2531	1.19e-32	129.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,23AZB@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposition of ISMyma03	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158347_k127_2991896_7	526225.Gobs_1216	6.813e-105	350.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4ESNN@85013|Frankiales	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2,rve_3
SRR25158347_k127_2991896_41	391626.OAN307_c03800	3.803e-09	64.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158347_k127_3008302_0	1449346.JQMO01000003_gene6713	0.0	1102.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,2M0XM@2063|Kitasatospora	201174|Actinobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158347_k127_3008302_8	1380356.JNIK01000014_gene3174	1.95e-77	276.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158347_k127_3008302_10	1380347.JNII01000007_gene756	6.44e-74	260.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.23.1.1,1.23.1.2,1.23.1.3,1.23.1.4	ko:K21568	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_10,NmrA
SRR25158347_k127_3008302_4	1122611.KB903959_gene4229	3.454e-103	351.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4EIIH@85012|Streptosporangiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158347_k127_3008302_18	351607.Acel_0515	3.595e-06	56.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3008302_2	1313172.YM304_29160	1.983e-123	402.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CP57@84992|Acidimicrobiia	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10041	ko02010,map02010	M00228,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
SRR25158347_k127_3008302_12	357808.RoseRS_4003	7.344e-62	240.0	COG0765@1|root,COG0765@2|Bacteria,2G845@200795|Chloroflexi,376Y4@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158347_k127_3008302_7	1081644.IMCC13023_09920	1.581e-80	282.0	COG4597@1|root,COG4597@2|Bacteria	2|Bacteria	P	amino acid transport	bgtB	-	-	ko:K09970,ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158347_k127_3008302_3	324602.Caur_3237	8.49e-105	354.0	COG0834@1|root,COG0834@2|Bacteria,2G7RH@200795|Chloroflexi,376Y9@32061|Chloroflexia	32061|Chloroflexia	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SRR25158347_k127_3008302_11	103733.JNYO01000018_gene3211	1.184e-69	261.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4DY1H@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158347_k127_3008302_15	1121381.JNIV01000013_gene4219	3.618e-45	175.0	COG2264@1|root,COG2264@2|Bacteria,1WJ0S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158347_k127_3008302_9	235985.BBPN01000001_gene1378	2.212e-76	272.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,2NGHU@228398|Streptacidiphilus	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158347_k127_3008302_5	479433.Caci_2251	5.755e-100	344.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_3008302_14	1236902.ANAS01000013_gene1249	1.855e-51	203.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4EI28@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158347_k127_3008302_6	479434.Sthe_1582	7.285e-90	313.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158347_k127_3008302_1	1385511.N783_19235	8.578e-191	616.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,2Y8UC@289201|Pontibacillus	91061|Bacilli	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158347_k127_3008302_13	1313172.YM304_38660	7.837e-62	220.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CNAV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158347_k127_3008302_17	1382356.JQMP01000004_gene57	1.475e-08	65.0	2EKS3@1|root,33EFV@2|Bacteria,2GBBM@200795|Chloroflexi,27YP9@189775|Thermomicrobia	189775|Thermomicrobia	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158347_k127_3008302_16	1313172.YM304_38640	1.603e-34	141.0	COG3336@1|root,COG3336@2|Bacteria,2HG9Q@201174|Actinobacteria,4CN83@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
SRR25158347_k127_302158_26	675635.Psed_5376	4.852e-34	139.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4E3RC@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158347_k127_302158_16	1298593.TOL_0399	2.664e-56	201.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XJIQ@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158347_k127_302158_14	397278.JOJN01000002_gene200	1.872e-57	212.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DPSE@85009|Propionibacteriales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158347_k127_302158_21	1211815.CBYP010000046_gene891	6.648e-45	171.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4ESN1@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158347_k127_302158_2	136273.GY22_05635	6.223e-105	353.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,1W7ZI@1268|Micrococcaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158347_k127_302158_5	477641.MODMU_4892	1.084e-79	270.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4EREE@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158347_k127_302158_19	316274.Haur_4938	3.141e-49	178.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,375IQ@32061|Chloroflexia	32061|Chloroflexia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158347_k127_302158_18	1463887.KL589966_gene2426	1.37e-53	192.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158347_k127_302158_33	585503.HMPREF7545_0799	7.134e-15	79.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4H629@909932|Negativicutes	909932|Negativicutes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158347_k127_302158_28	667014.Thein_1486	1.907e-29	132.0	COG0361@1|root,COG0361@2|Bacteria,2GI0P@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158347_k127_302158_4	926561.KB900619_gene2568	3.967e-83	290.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158347_k127_302158_8	1944.JOAZ01000028_gene1617	4.408e-79	270.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,41A6C@629295|Streptomyces griseus group	201174|Actinobacteria	F	Adenylate kinase, active site lid	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158347_k127_302158_0	110319.CF8_0696	1.443e-150	491.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4DN3Y@85009|Propionibacteriales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158347_k127_302158_22	926564.KI911686_gene5612	7.153e-43	168.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4F4FB@85017|Promicromonosporaceae	201174|Actinobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158347_k127_302158_34	743719.PaelaDRAFT_5398	1.88e-12	75.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,2703T@186822|Paenibacillaceae	91061|Bacilli	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158347_k127_302158_10	1380386.JIAW01000012_gene1927	3.96e-67	237.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,233YI@1762|Mycobacteriaceae	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158347_k127_302158_24	103733.JNYO01000004_gene7979	9.939e-36	139.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4E3EI@85010|Pseudonocardiales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158347_k127_302158_9	435830.HMPREF0045_01550	4.097e-69	239.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4D3X4@85005|Actinomycetales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158347_k127_302158_17	471852.Tcur_4307	1.438e-55	197.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4EINA@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158347_k127_302158_31	1114959.SZMC14600_07686	1.243e-24	113.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4E6JP@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158347_k127_302158_6	525909.Afer_0410	1.488e-79	269.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CMX7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158347_k127_302158_29	525146.Ddes_0671	5.451e-28	122.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MC5T@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158347_k127_302158_12	1229203.KI301992_gene2091	3.955e-60	209.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,3UWIV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158347_k127_302158_30	408672.NBCG_03640	2.71e-27	117.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4DRI1@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158347_k127_302158_32	525263.HMPREF0298_2147	5.75e-19	89.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,22NTK@1653|Corynebacteriaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158347_k127_302158_13	1121423.JONT01000027_gene651	6.469e-60	210.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,261KH@186807|Peptococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158347_k127_302158_3	585531.HMPREF0063_13043	2.689e-85	301.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4DNUB@85009|Propionibacteriales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158347_k127_302158_27	1121365.AQXB01000004_gene1862	2.915e-33	136.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,22N5U@1653|Corynebacteriaceae	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158347_k127_302158_23	1157490.EL26_19175	1.446e-42	160.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,279Z4@186823|Alicyclobacillaceae	91061|Bacilli	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158347_k127_302158_1	656024.FsymDg_3958	2.805e-119	388.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4ES62@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158347_k127_302158_25	767029.HMPREF9154_2274	1.499e-34	135.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4DR9N@85009|Propionibacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158347_k127_302158_11	1111131.HMPREF1255_0328	7.029e-67	234.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4DN59@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158347_k127_302158_7	1303692.SFUL_4488	2.76e-79	270.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158347_k127_302158_20	1203605.HMPREF1531_00183	2.269e-48	174.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4DQJR@85009|Propionibacteriales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158347_k127_302158_15	351607.Acel_0304	7.311e-57	198.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158347_k127_3024004_3	1229780.BN381_10211	1.09e-28	124.0	2CIFA@1|root,348QY@2|Bacteria,2H88E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3024004_0	1229780.BN381_10212	1.559e-191	616.0	COG2304@1|root,COG2304@2|Bacteria,2HQ9B@201174|Actinobacteria,3UXG6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
SRR25158347_k127_3024004_4	1278073.MYSTI_06457	1.848e-15	88.0	COG1840@1|root,COG1840@2|Bacteria,1QX5Y@1224|Proteobacteria,42PKC@68525|delta/epsilon subdivisions,2WISI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
SRR25158347_k127_3024004_1	1313172.YM304_23480	4.355e-134	443.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria,4CNTH@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158347_k127_3024004_2	1120948.KB903223_gene263	1.637e-131	423.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4DXCZ@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158347_k127_3043994_38	1043493.BBLU01000006_gene2203	1.802e-07	53.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
SRR25158347_k127_3043994_21	710696.Intca_3500	4.4e-55	199.0	COG0662@1|root,COG0662@2|Bacteria,2HY3R@201174|Actinobacteria,4FJNW@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158347_k127_3043994_2	446471.Xcel_2128	5.978e-225	706.0	COG1249@1|root,COG1249@2|Bacteria,2I6E8@201174|Actinobacteria	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3043994_35	469383.Cwoe_1708	6.788e-15	85.0	COG1277@1|root,COG1277@2|Bacteria,2HGDW@201174|Actinobacteria,4CTSG@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3043994_12	269800.Tfu_1436	2.175e-90	306.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4EFY4@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_3043994_11	1049564.TevJSym_ae00690	7.733e-95	325.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158347_k127_3043994_34	710686.Mycsm_03429	2.255e-17	88.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158347_k127_3043994_5	391037.Sare_3193	1.165e-130	424.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4DBTB@85008|Micromonosporales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_3043994_23	1463900.JOIX01000011_gene3313	9.387e-47	188.0	COG2730@1|root,COG2730@2|Bacteria,2HQAQ@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
SRR25158347_k127_3043994_27	443218.AS9A_2968	1.156e-41	156.0	COG2146@1|root,COG2146@2|Bacteria,2GVQV@201174|Actinobacteria,23EGB@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158347_k127_3043994_18	1127134.NOCYR_2237	9.186e-65	242.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4FVN0@85025|Nocardiaceae	201174|Actinobacteria	S	Methyltransferase small domain	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158347_k127_3043994_31	1313172.YM304_29780	3.382e-36	145.0	COG3797@1|root,COG3797@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158347_k127_3043994_8	1416759.AYMR01000009_gene3323	2.374e-123	408.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4FS5J@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158347_k127_3043994_39	710243.XP_007595649.1	3.235e-05	56.0	COG0604@1|root,KOG1198@2759|Eukaryota	2759|Eukaryota	C	oxidoreductase activity	IFR1	GO:0003674,GO:0003824,GO:0004029,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0008152,GO:0010033,GO:0010035,GO:0010038,GO:0014070,GO:0016491,GO:0016620,GO:0016903,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0046688,GO:0050896,GO:0055114,GO:1901426,GO:1901700	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_3043994_22	479432.Sros_0745	4.946e-50	185.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4EI66@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158347_k127_3043994_40	391625.PPSIR1_23474	0.0001322	50.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_3043994_33	1449048.JQKU01000030_gene4201	2.82e-21	98.0	2DWQF@1|root,341EX@2|Bacteria,2IJK7@201174|Actinobacteria,23F2Z@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3043994_20	1100721.ALKO01000033_gene245	1.123e-57	218.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria,1R0WG@1224|Proteobacteria,2WI7R@28216|Betaproteobacteria,4AK4P@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_3043994_14	1122611.KB903961_gene4422	4.915e-89	304.0	COG2273@1|root,COG2273@2|Bacteria,2GTJC@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRR25158347_k127_3043994_17	926560.KE387023_gene2409	1.058e-76	268.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	MA20_21040	-	1.1.1.193,1.1.1.302,3.5.4.26	ko:K00082,ko:K11752,ko:K14654	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459,R09375,R09376	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158347_k127_3043994_24	1150864.MILUP08_40329	1.067e-45	179.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4D9V1@85008|Micromonosporales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158347_k127_3043994_6	1996.JOFO01000029_gene6824	3.385e-128	423.0	COG2755@1|root,COG2755@2|Bacteria,2GKSW@201174|Actinobacteria,4EMSP@85012|Streptosporangiales	201174|Actinobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158347_k127_3043994_19	1429046.RR21198_5586	1.737e-58	207.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,4G1QC@85025|Nocardiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SRR25158347_k127_3043994_26	28444.JODQ01000002_gene4110	4.827e-42	164.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4EIVP@85012|Streptosporangiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158347_k127_3043994_25	525904.Tter_1921	2.093e-43	168.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158347_k127_3043994_0	42256.RradSPS_2597	5.529e-265	849.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158347_k127_3043994_16	298655.KI912266_gene3515	1.019e-78	272.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4ESF9@85013|Frankiales	201174|Actinobacteria	S	phenazine biosynthesis protein PhzF	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158347_k127_3043994_29	1037409.BJ6T_04150	1.053e-39	167.0	COG3119@1|root,COG3119@2|Bacteria,1MYHH@1224|Proteobacteria,2UA67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_3043994_13	646529.Desaci_2502	4.53e-90	303.0	COG0412@1|root,COG0412@2|Bacteria,1UZRU@1239|Firmicutes	1239|Firmicutes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158347_k127_3043994_37	2002.JOEQ01000003_gene2496	1.343e-10	72.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3043994_36	1123226.KB899303_gene2923	1.791e-13	78.0	COG3832@1|root,COG3832@2|Bacteria,1VI54@1239|Firmicutes,4HPK7@91061|Bacilli,272WJ@186822|Paenibacillaceae	91061|Bacilli	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3043994_30	1121019.AUMN01000002_gene272	2.227e-37	161.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,1W8EM@1268|Micrococcaceae	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158347_k127_3043994_28	1121946.AUAX01000025_gene6400	1.266e-40	158.0	COG1309@1|root,COG1309@2|Bacteria,2I31S@201174|Actinobacteria,4DE3F@85008|Micromonosporales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158347_k127_3043994_10	1356854.N007_14445	3.674e-102	347.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158347_k127_3043994_7	1120959.ATXF01000005_gene1223	1.449e-123	411.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_3043994_32	1219080.VEZ01S_02_00610	8.197e-25	113.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T1Y4@1236|Gammaproteobacteria,1XTDR@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	chiS	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,Response_reg
SRR25158347_k127_3043994_1	1151119.KB895489_gene650	5.014e-244	766.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria	201174|Actinobacteria	I	synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_3043994_3	1449976.KALB_4170	4.896e-137	450.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4E12D@85010|Pseudonocardiales	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158347_k127_3043994_4	467200.ACFA01000086_gene1348	1.606e-134	449.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158347_k127_3043994_9	55952.BU52_03405	2.415e-104	355.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158347_k127_3053719_11	232348.ADXL01000059_gene2422	1.988e-25	108.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria,1GZEW@1129|Synechococcus	1117|Cyanobacteria	H	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_3053719_10	1313172.YM304_04890	4.898e-28	117.0	COG1977@1|root,COG1977@2|Bacteria,2HH1D@201174|Actinobacteria,4CP1M@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158347_k127_3053719_14	1504672.669785636	3.495e-06	60.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,2WEXX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_3053719_9	1122622.ATWJ01000008_gene2903	3.484e-28	132.0	COG2132@1|root,COG2385@1|root,COG2132@2|Bacteria,COG2385@2|Bacteria,2IDP7@201174|Actinobacteria,4FIWI@85021|Intrasporangiaceae	201174|Actinobacteria	Q	sporulation resulting in formation of a cellular spore	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158347_k127_3053719_8	235985.BBPN01000004_gene3168	1.236e-31	133.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,2NHT4@228398|Streptacidiphilus	201174|Actinobacteria	F	Peptidase C26	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158347_k127_3053719_6	543632.JOJL01000017_gene9894	3.733e-59	218.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4DA14@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158347_k127_3053719_13	1068978.AMETH_0071	4.853e-21	98.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4E3SA@85010|Pseudonocardiales	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158347_k127_3053719_7	1278078.G419_22379	3.403e-38	149.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,4G0VQ@85025|Nocardiaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR25158347_k127_3053719_12	203124.Tery_3372	3.441e-21	100.0	COG2335@1|root,COG2335@2|Bacteria,1G6R4@1117|Cyanobacteria,1HBIV@1150|Oscillatoriales	1117|Cyanobacteria	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158347_k127_3053719_1	526225.Gobs_2278	1.355e-150	489.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4ESDI@85013|Frankiales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_3053719_4	35754.JNYJ01000001_gene7306	9.352e-96	328.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4DBE1@85008|Micromonosporales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_3053719_2	195250.CM001776_gene3868	2.419e-140	451.0	COG0189@1|root,COG0189@2|Bacteria,1G0DT@1117|Cyanobacteria,1GYKT@1129|Synechococcus	1117|Cyanobacteria	F	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,Zn_protease
SRR25158347_k127_3053719_3	316274.Haur_3716	5.39e-98	332.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3053719_5	1157637.KB892093_gene6780	9.687e-68	235.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158347_k127_3053719_0	1385514.N782_19560	1.237e-282	882.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4IV7Y@91061|Bacilli,2Y8NK@289201|Pontibacillus	91061|Bacilli	C	Aconitate hydratase	thrS	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158347_k127_307203_60	68260.JOAY01000018_gene3262	2.314e-05	47.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158347_k127_307203_21	748247.AZKH_4188	1.089e-89	320.0	COG3279@1|root,COG5001@1|root,COG3279@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9,Response_reg
SRR25158347_k127_307203_31	1045009.AFXQ01000017_gene263	7.947e-71	251.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,1WAJ3@1268|Micrococcaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158347_k127_307203_2	1229780.BN381_310023	2.334e-197	634.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,3UWGJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158347_k127_307203_11	1157490.EL26_14955	1.25e-133	447.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,27948@186823|Alicyclobacillaceae	91061|Bacilli	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158347_k127_307203_52	1096930.L284_17260	9.818e-29	130.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TSVW@28211|Alphaproteobacteria,2K3AS@204457|Sphingomonadales	204457|Sphingomonadales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158347_k127_307203_44	477974.Daud_1132	3.175e-42	173.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia,261B5@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_307203_22	479431.Namu_3522	1.431e-88	311.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,4EUTU@85013|Frankiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158347_k127_307203_46	351607.Acel_1088	1.944e-39	165.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4ES9K@85013|Frankiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158347_k127_307203_36	1089550.ATTH01000002_gene32	1.753e-59	217.0	COG0670@1|root,COG0670@2|Bacteria,4NFZ7@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
SRR25158347_k127_307203_27	1120949.KB903304_gene6945	4.134e-77	268.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria,4D9BH@85008|Micromonosporales	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_307203_16	298655.KI912266_gene382	3.63e-125	409.0	COG0492@1|root,COG0492@2|Bacteria,2GJ1Z@201174|Actinobacteria,4ERYC@85013|Frankiales	201174|Actinobacteria	C	Ferredoxin--NADP reductase	-	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_307203_10	656024.FsymDg_0771	1.434e-136	457.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4ERSP@85013|Frankiales	201174|Actinobacteria	S	von Willebrand factor type A	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158347_k127_307203_7	471852.Tcur_1054	2.291e-161	521.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4EGIC@85012|Streptosporangiales	201174|Actinobacteria	H	Sigma-54 interaction domain	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
SRR25158347_k127_307203_45	1313172.YM304_26200	3.377e-41	171.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158347_k127_307203_20	298654.FraEuI1c_2223	1.049e-97	331.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_307203_47	1410668.JNKC01000004_gene156	7.332e-37	158.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,36DM6@31979|Clostridiaceae	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158347_k127_307203_29	675635.Psed_3573	1.877e-74	267.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DY5S@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YibE F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158347_k127_307203_54	1137268.AZXF01000031_gene921	3.132e-13	83.0	COG3087@1|root,COG3087@2|Bacteria,2GNX9@201174|Actinobacteria,4EIUA@85012|Streptosporangiales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_307203_24	298655.KI912266_gene5297	1.897e-80	282.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_307203_40	1382304.JNIL01000001_gene2908	3.606e-49	181.0	COG0346@1|root,COG0346@2|Bacteria,1V6KX@1239|Firmicutes,4HJMS@91061|Bacilli	91061|Bacilli	E	Lactoylglutathione lyase and related lyases	yqjT	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158347_k127_307203_25	373903.Hore_12590	7.374e-80	292.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,3WA9K@53433|Halanaerobiales	186801|Clostridia	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158347_k127_307203_42	479437.Elen_1326	1.086e-44	173.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria,4CUK0@84998|Coriobacteriia	84998|Coriobacteriia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158347_k127_307203_15	1111479.AXAR01000006_gene748	6.947e-126	419.0	COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli	91061|Bacilli	F	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158347_k127_307203_28	1121877.JQKF01000069_gene1265	6.385e-76	273.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4CMYW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158347_k127_307203_19	1214242.B446_27415	4.743e-111	370.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158347_k127_307203_38	1206741.BAFX01000002_gene5596	1.828e-56	218.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4FWVM@85025|Nocardiaceae	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158347_k127_307203_43	469383.Cwoe_1307	1.179e-43	165.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CQF3@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158347_k127_307203_35	479431.Namu_3445	1.15e-59	222.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158347_k127_307203_32	929712.KI912613_gene49	2.776e-70	262.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4CTHM@84995|Rubrobacteria	84995|Rubrobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158347_k127_307203_23	1121272.KB903257_gene5483	5.073e-84	291.0	2EWQK@1|root,33Q2D@2|Bacteria,2IJ4T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_307203_1	469371.Tbis_2156	2.015e-209	676.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4DYAF@85010|Pseudonocardiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158347_k127_307203_5	1313172.YM304_28200	2.025e-170	557.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4CP4J@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158347_k127_307203_12	882083.SacmaDRAFT_1994	4.336e-132	441.0	COG1073@1|root,COG1073@2|Bacteria,2ID35@201174|Actinobacteria	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S15
SRR25158347_k127_307203_8	1123320.KB889747_gene7183	4.42e-147	484.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRR25158347_k127_307203_3	1123320.KB889747_gene7184	2.711e-190	600.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_307203_53	1313172.YM304_20200	6.876e-26	121.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158347_k127_307203_9	926550.CLDAP_06320	1.116e-145	467.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_307203_58	479432.Sros_7943	2.471e-08	63.0	2C5NN@1|root,2ZJPF@2|Bacteria,2GV7Y@201174|Actinobacteria,4EKGV@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_307203_55	298654.FraEuI1c_0686	1.438e-12	80.0	COG3832@1|root,COG3832@2|Bacteria,2IH7G@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_307203_50	521011.Mpal_0582	1.712e-29	131.0	COG0496@1|root,arCOG02303@2157|Archaea,2XT5R@28890|Euryarchaeota,2N9DM@224756|Methanomicrobia	224756|Methanomicrobia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A1192	SurE
SRR25158347_k127_307203_4	1229780.BN381_450063	2.006e-177	567.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,3UX3I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_4,Malic_M,malic
SRR25158347_k127_307203_26	1122603.ATVI01000005_gene3699	2.739e-78	278.0	COG1075@1|root,COG1075@2|Bacteria,1R4ZC@1224|Proteobacteria,1RSBJ@1236|Gammaproteobacteria,1X7QG@135614|Xanthomonadales	135614|Xanthomonadales	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRR25158347_k127_307203_13	390989.JOEG01000009_gene1127	8.205e-127	416.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4D93W@85008|Micromonosporales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_307203_49	710111.FraQA3DRAFT_1436	1.13e-29	130.0	2C7KP@1|root,32UAQ@2|Bacteria,2GMCX@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
SRR25158347_k127_307203_37	1112204.GPOL_c42840	1.324e-58	208.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4GE94@85026|Gordoniaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	ddn	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158347_k127_307203_39	701347.Entcl_3783	5.148e-53	215.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2366 Protein related to penicillin acylase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158347_k127_307203_0	1108045.GORHZ_205_00370	4.008e-276	871.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4GC7B@85026|Gordoniaceae	201174|Actinobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
SRR25158347_k127_307203_33	1089546.AQUI01000002_gene952	1.686e-63	224.0	COG0655@1|root,COG0655@2|Bacteria,2II43@201174|Actinobacteria,4097B@622450|Actinopolysporales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158347_k127_307203_17	443218.AS9A_2477	2.874e-114	379.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,233P7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRR25158347_k127_307203_14	1293054.HSACCH_00441	1.051e-126	409.0	COG0655@1|root,COG0655@2|Bacteria,1TSEC@1239|Firmicutes	1239|Firmicutes	S	COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158347_k127_307203_41	479432.Sros_5640	9.585e-47	192.0	COG1597@1|root,COG1597@2|Bacteria,2GNTZ@201174|Actinobacteria,4EJ1P@85012|Streptosporangiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158347_k127_307203_51	234267.Acid_3142	2.328e-29	124.0	COG2085@1|root,COG2085@2|Bacteria,3Y5CN@57723|Acidobacteria	57723|Acidobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158347_k127_307203_30	1157637.KB892092_gene6989	4.239e-73	250.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158347_k127_307203_6	1123258.AQXZ01000019_gene3368	6.129e-165	524.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4FYT4@85025|Nocardiaceae	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158347_k127_307203_57	1380390.JIAT01000010_gene4826	5.927e-12	74.0	2DE9W@1|root,2ZM4H@2|Bacteria,2I6N5@201174|Actinobacteria,4CT2M@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_307203_34	1348663.KCH_47070	5.212e-61	228.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,2M05I@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158347_k127_307203_18	590998.Celf_1685	7.516e-112	370.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_307203_48	446462.Amir_3351	7.383e-32	126.0	COG2261@1|root,COG2261@2|Bacteria,2IQY7@201174|Actinobacteria,4E6D3@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158347_k127_307203_56	1041138.KB890244_gene5085	4.386e-12	66.0	2C1EG@1|root,2Z7MZ@2|Bacteria,1NQTP@1224|Proteobacteria,2UPDR@28211|Alphaproteobacteria,4BAAM@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3120039_0	298653.Franean1_2057	0.0	1340.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ERXD@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158347_k127_3120039_12	697281.Mahau_0230	1.301e-25	124.0	COG1404@1|root,COG2247@1|root,COG3858@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,COG3858@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
SRR25158347_k127_3120039_9	1463841.JOIR01000011_gene2747	4.888e-56	215.0	COG5305@1|root,COG5305@2|Bacteria,2IDAQ@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
SRR25158347_k127_3120039_13	452863.Achl_2414	1.274e-16	89.0	COG2456@1|root,COG2456@2|Bacteria,2GQZ0@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SRR25158347_k127_3120039_7	1001240.GY21_17045	5.375e-71	248.0	COG1216@1|root,COG1216@2|Bacteria,2I2J1@201174|Actinobacteria,4FMKF@85023|Microbacteriaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	ycbB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_3120039_11	1385520.N802_13040	1.023e-32	149.0	COG0726@1|root,COG2247@1|root,COG0726@2|Bacteria,COG2247@2|Bacteria,2HX9Q@201174|Actinobacteria,4FFZ3@85021|Intrasporangiaceae	201174|Actinobacteria	GM	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Polysacc_deac_1
SRR25158347_k127_3120039_1	1380347.JNII01000005_gene3602	9.563e-196	629.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4ERT0@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158347_k127_3120039_6	101510.RHA1_ro07174	8.275e-91	308.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4FUYU@85025|Nocardiaceae	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158347_k127_3120039_8	446468.Ndas_3012	3.69e-67	239.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4EHPS@85012|Streptosporangiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158347_k127_3120039_10	446469.Sked_20040	8.939e-38	154.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158347_k127_3120039_4	1463845.JOIG01000007_gene623	7.977e-137	452.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158347_k127_3120039_5	903814.ELI_0662	1.269e-131	435.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,25V9X@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158347_k127_3120039_2	1380356.JNIK01000005_gene901	1.966e-159	522.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EUMQ@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_3120039_3	1463858.JOHR01000001_gene6170	9.169e-150	501.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_3129045_9	118173.KB235914_gene2890	1.174e-161	521.0	COG0021@1|root,COG0021@2|Bacteria,1G0GC@1117|Cyanobacteria,1H7T2@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158347_k127_3129045_10	42256.RradSPS_1100	2.038e-148	488.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158347_k127_3129045_36	913325.N799_08050	6.03e-24	106.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1X701@135614|Xanthomonadales	135614|Xanthomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158347_k127_3129045_22	1349820.M707_00030	3.911e-38	152.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,1WBSU@1268|Micrococcaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158347_k127_3129045_17	1229780.BN381_130049	9.773e-83	298.0	COG0318@1|root,COG0318@2|Bacteria,2H33T@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_3129045_28	1313172.YM304_23350	7.982e-31	134.0	COG3428@1|root,COG3428@2|Bacteria,2HGDA@201174|Actinobacteria,4CNBH@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158347_k127_3129045_16	35754.JNYJ01000013_gene1052	8.173e-96	340.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria,4D8V4@85008|Micromonosporales	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRR25158347_k127_3129045_29	232348.ADXL01000060_gene2444	3.379e-28	122.0	2AWZQ@1|root,31NXM@2|Bacteria,1G6ZZ@1117|Cyanobacteria,1H092@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3129045_8	1123023.JIAI01000001_gene6257	7.467e-163	533.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4E1ZB@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158347_k127_3129045_4	1121385.AQXW01000004_gene3170	1.431e-196	633.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158347_k127_3129045_38	357808.RoseRS_4206	3.711e-12	77.0	COG0526@1|root,COG0526@2|Bacteria,2GACV@200795|Chloroflexi,375FU@32061|Chloroflexia	32061|Chloroflexia	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
SRR25158347_k127_3129045_15	1449058.JQKT01000009_gene184	4.338e-112	395.0	COG3629@1|root,COG3629@2|Bacteria,2HFJF@201174|Actinobacteria,4FSUE@85023|Microbacteriaceae	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158347_k127_3129045_30	1449058.JQKT01000009_gene185	1.205e-27	118.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,GAF_2,GAF_3,HAMP,HATPase_c,HATPase_c_2,HATPase_c_3,Response_reg,SpoIIE,dCache_1
SRR25158347_k127_3129045_33	1177594.MIC448_2190008	1.914e-25	112.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K03090,ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158347_k127_3129045_26	1443111.JASG01000004_gene3101	4.069e-32	130.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2UAEV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158347_k127_3129045_14	526225.Gobs_0017	2.275e-118	389.0	COG1309@1|root,COG1309@2|Bacteria,2GQRD@201174|Actinobacteria,4ETEK@85013|Frankiales	201174|Actinobacteria	K	transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158347_k127_3129045_7	526225.Gobs_0019	6.257e-177	567.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158347_k127_3129045_18	1348338.ADILRU_2321	3.724e-74	253.0	arCOG06733@1|root,313GU@2|Bacteria,2ICAF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3129045_32	1255043.TVNIR_1550	1.681e-25	115.0	COG2010@1|root,COG2010@2|Bacteria,1MZSK@1224|Proteobacteria,1SDUY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158347_k127_3129045_19	44454.NF84_21020	2.209e-62	225.0	COG1656@1|root,COG1656@2|Bacteria,2GMQR@201174|Actinobacteria,23528@1762|Mycobacteriaceae	201174|Actinobacteria	S	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
SRR25158347_k127_3129045_20	1120948.KB903225_gene5544	3.534e-58	220.0	COG3011@1|root,COG3011@2|Bacteria,2GN4W@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
SRR25158347_k127_3129045_2	710687.KI912270_gene5336	5.979e-226	744.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,232J4@1762|Mycobacteriaceae	201174|Actinobacteria	C	glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
SRR25158347_k127_3129045_0	351607.Acel_1078	0.0	2172.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4ERS2@85013|Frankiales	201174|Actinobacteria	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158347_k127_3129045_13	316274.Haur_1430	8.204e-121	426.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158347_k127_3129045_11	100226.SCO3443	5.889e-147	479.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_3129045_24	857087.Metme_0082	1.157e-33	139.0	COG0454@1|root,COG0456@2|Bacteria,1QZJR@1224|Proteobacteria,1S8SA@1236|Gammaproteobacteria,1XGZ5@135618|Methylococcales	135618|Methylococcales	H	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3129045_35	1408437.JNJN01000041_gene155	1.892e-24	111.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,25XMY@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3129045_27	1172188.KB911820_gene3085	1.813e-31	130.0	28RB9@1|root,2ZDQU@2|Bacteria,2GZQK@201174|Actinobacteria,4FIZG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3129045_3	2002.JOEQ01000005_gene3812	6.627e-215	675.0	COG0803@1|root,COG0803@2|Bacteria,2IAV8@201174|Actinobacteria,4EQ9A@85012|Streptosporangiales	201174|Actinobacteria	P	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
SRR25158347_k127_3129045_25	1128421.JAGA01000003_gene3162	5.963e-33	139.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_3,Cupredoxin_1
SRR25158347_k127_3129045_31	1385521.N803_05695	7.875e-27	123.0	COG5662@1|root,COG5662@2|Bacteria,2I196@201174|Actinobacteria,4FHP7@85021|Intrasporangiaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158347_k127_3129045_21	101510.RHA1_ro00601	1.034e-41	164.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria,4G0WH@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158347_k127_3129045_23	314285.KT71_11259	1.046e-33	141.0	COG2050@1|root,COG2050@2|Bacteria,1Q6G9@1224|Proteobacteria,1SM4B@1236|Gammaproteobacteria,1J8UA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158347_k127_3129045_12	469383.Cwoe_2539	1.582e-121	405.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158347_k127_3129045_6	469371.Tbis_3236	1.531e-178	567.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria,4DYZ6@85010|Pseudonocardiales	201174|Actinobacteria	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158347_k127_3129045_37	1382306.JNIM01000001_gene190	3.725e-22	99.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi	200795|Chloroflexi	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158347_k127_3129045_1	479432.Sros_3809	1.178e-296	936.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4EMM0@85012|Streptosporangiales	201174|Actinobacteria	O	HypF finger	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158347_k127_3129045_5	450380.JPSY01000001_gene1471	1.63e-187	606.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4FQTU@85023|Microbacteriaceae	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158347_k127_3156082_5	350054.Mflv_0717	4.753e-32	132.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,235A1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158347_k127_3156082_8	549.BW31_00162	1.192e-11	70.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,3W0ZR@53335|Pantoea	1236|Gammaproteobacteria	L	Methyltransferase	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
SRR25158347_k127_3156082_3	219305.MCAG_04077	3.703e-108	357.0	28KEA@1|root,2ZA0J@2|Bacteria,2I9YN@201174|Actinobacteria,4DCRZ@85008|Micromonosporales	201174|Actinobacteria	H	Sulfotransferase domain	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
SRR25158347_k127_3156082_4	1394178.AWOO02000044_gene4476	3.764e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_3156082_0	1133849.O3I_026255	2.285e-214	691.0	COG0577@1|root,COG0577@2|Bacteria,2HHSC@201174|Actinobacteria,4FZWK@85025|Nocardiaceae	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_3156082_6	211165.AJLN01000081_gene1031	5.34e-24	109.0	COG1309@1|root,COG1309@2|Bacteria,1GKDE@1117|Cyanobacteria,1JKYI@1189|Stigonemataceae	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3156082_1	526225.Gobs_1069	1.6e-148	503.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4ES6Q@85013|Frankiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158347_k127_3156082_2	1304275.C41B8_18181	3.379e-114	373.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRR25158347_k127_3164133_0	106370.Francci3_4383	1.556e-263	821.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4ERE5@85013|Frankiales	201174|Actinobacteria	O	Clp domain protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158347_k127_3164133_2	1169161.KB897730_gene1131	1.105e-129	450.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158347_k127_3164133_4	55952.BU52_07405	1.279e-70	269.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158347_k127_3164133_1	1254432.SCE1572_08575	1.179e-139	458.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2Z06Y@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158347_k127_3164133_5	1306406.ASHX01000001_gene2100	4.783e-63	224.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158347_k127_3164133_3	1313172.YM304_14260	1.656e-88	302.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CNWS@84992|Acidimicrobiia	84992|Acidimicrobiia	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158347_k127_3176319_5	298654.FraEuI1c_4948	0.0005468	51.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158347_k127_3176319_0	266117.Rxyl_1063	6.383e-190	606.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CPBQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158347_k127_3176319_1	1242864.D187_001620	2.777e-127	415.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,2YV1U@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158347_k127_3176319_4	479431.Namu_4971	1.149e-68	246.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4ESCZ@85013|Frankiales	201174|Actinobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158347_k127_3176319_2	404589.Anae109_3740	4.944e-86	308.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158347_k127_3176319_3	1306174.JODP01000025_gene4146	1.242e-78	275.0	COG0500@1|root,COG2226@2|Bacteria,2IINW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158347_k127_3207031_2	479435.Kfla_3037	2.196e-69	246.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4DMXV@85009|Propionibacteriales	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158347_k127_3207031_1	1269813.ATUL01000004_gene2226	1.316e-98	342.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1WY8J@135613|Chromatiales	135613|Chromatiales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158347_k127_3207031_3	1444309.JAQG01000087_gene2593	1.789e-49	187.0	COG2227@1|root,COG2227@2|Bacteria,1UHU9@1239|Firmicutes,4HFRY@91061|Bacilli,277EV@186822|Paenibacillaceae	91061|Bacilli	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_3207031_5	195253.Syn6312_2705	1.513e-06	55.0	COG1611@1|root,COG1611@2|Bacteria,1G5P3@1117|Cyanobacteria,1H212@1129|Synechococcus	1117|Cyanobacteria	S	TIGRFAM TIGR00725 family protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158347_k127_3207031_4	471855.Shel_15220	8.367e-39	147.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CW3C@84998|Coriobacteriia	84998|Coriobacteriia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158347_k127_3207031_0	103733.JNYO01000013_gene4334	3.893e-151	496.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4DYDE@85010|Pseudonocardiales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158347_k127_3234216_7	1463887.KL590004_gene1974	2.618e-52	199.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158347_k127_3234216_6	479433.Caci_8160	1.33e-54	218.0	COG1414@1|root,COG1414@2|Bacteria,2GP02@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158347_k127_3234216_0	298654.FraEuI1c_2263	1.74e-300	941.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4ERSS@85013|Frankiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158347_k127_3234216_2	479433.Caci_8161	2.214e-103	347.0	COG2755@1|root,COG2755@2|Bacteria,2GM52@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_3
SRR25158347_k127_3234216_3	1463820.JOGW01000004_gene4521	3.877e-90	306.0	COG1028@1|root,COG1028@2|Bacteria,2IENS@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_3234216_1	479433.Caci_8163	1.18e-157	507.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_3234216_5	862751.SACTE_3856	2.228e-56	205.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_3234216_4	246196.MSMEI_2189	1.257e-70	244.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria,2355H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158347_k127_3234216_8	1108045.GORHZ_069_00930	2.897e-06	49.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4GADF@85026|Gordoniaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRR25158347_k127_3245302_1	1229780.BN381_150043	7.783e-109	364.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWCM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_3245302_5	1229780.BN381_150047	1.146e-38	149.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,3UWVQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158347_k127_3245302_7	35754.JNYJ01000030_gene7641	2.144e-21	101.0	2E6TR@1|root,331DK@2|Bacteria,2IQF8@201174|Actinobacteria,4DEPE@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3245302_2	2074.JNYD01000010_gene998	6.586e-73	258.0	COG1063@1|root,COG1063@2|Bacteria,2GNFX@201174|Actinobacteria,4E2BI@85010|Pseudonocardiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_3245302_10	298653.Franean1_6517	2.062e-13	78.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CD225,DUF4339,zinc_ribbon_2
SRR25158347_k127_3245302_6	1048339.KB913029_gene1929	5.106e-30	131.0	2E37T@1|root,32Y7G@2|Bacteria,2HKTZ@201174|Actinobacteria,4EWSP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158347_k127_3245302_3	321327.CYA_1482	1.897e-61	217.0	COG0652@1|root,COG0652@2|Bacteria,1G5BD@1117|Cyanobacteria,1H0AB@1129|Synechococcus	1117|Cyanobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rot	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158347_k127_3245302_4	1128421.JAGA01000001_gene2135	2.183e-50	189.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.11.1,5.2.1.8	ko:K01802,ko:K03767,ko:K03768,ko:K12132	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158347_k127_3245302_8	1137269.AZWL01000019_gene4081	8.135e-17	84.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3245302_9	106370.Francci3_3693	1.316e-16	87.0	COG3339@1|root,COG3339@2|Bacteria,2IMW8@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158347_k127_3245302_0	909613.UO65_4262	2.173e-213	677.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DX5C@85010|Pseudonocardiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158347_k127_3245302_12	743525.TSC_c16700	2.282e-06	55.0	COG3255@1|root,COG3255@2|Bacteria,1WMIK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158347_k127_3245302_11	662479.C440_15574	4.645e-09	67.0	COG1266@1|root,arCOG02766@2157|Archaea,2Y839@28890|Euryarchaeota,23X08@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158347_k127_3252516_5	58123.JOFJ01000029_gene1147	1.796e-18	99.0	COG0642@1|root,COG2205@2|Bacteria,2I3ZX@201174|Actinobacteria,4EQRH@85012|Streptosporangiales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HAMP,HATPase_c,HisKA
SRR25158347_k127_3252516_3	326424.FRAAL6202	1.017e-99	340.0	COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4ERNC@85013|Frankiales	201174|Actinobacteria	T	SMART Nucleotide binding protein, PINc	phoH2	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SRR25158347_k127_3252516_6	35754.JNYJ01000047_gene3469	5.312e-15	86.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria,4DG0H@85008|Micromonosporales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158347_k127_3252516_0	644283.Micau_3749	1.31e-174	556.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4D936@85008|Micromonosporales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158347_k127_3252516_4	760568.Desku_1348	7.586e-55	205.0	COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia,260C4@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158347_k127_3252516_2	644283.Micau_3750	3.441e-110	377.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4DAYK@85008|Micromonosporales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158347_k127_3252516_1	675635.Psed_4200	2.455e-170	553.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E0R9@85010|Pseudonocardiales	201174|Actinobacteria	S	protein involved in propionate catabolism	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158347_k127_3260766_3	1408254.T458_23940	2.845e-06	57.0	COG0265@1|root,COG0265@2|Bacteria,1VJY1@1239|Firmicutes,4HQS3@91061|Bacilli,2715A@186822|Paenibacillaceae	91061|Bacilli	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158347_k127_3260766_0	1380390.JIAT01000009_gene522	6.324e-276	861.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158347_k127_3260766_1	479432.Sros_3100	2.183e-70	248.0	COG2808@1|root,COG2808@2|Bacteria,2I9QJ@201174|Actinobacteria,4EJ9I@85012|Streptosporangiales	201174|Actinobacteria	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158347_k127_3260766_2	485913.Krac_2634	5.331e-27	115.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS
SRR25158347_k127_3274839_0	926564.KI911665_gene627	2.016e-139	481.0	COG1404@1|root,COG3979@1|root,COG1404@2|Bacteria,COG3979@2|Bacteria,2GK3D@201174|Actinobacteria,4F5NW@85017|Promicromonosporaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
SRR25158347_k127_3274839_4	1197130.BAFM01000004_gene996	1.517e-12	82.0	COG3291@1|root,COG3979@1|root,arCOG07781@1|root,arCOG10187@1|root,arCOG02546@2157|Archaea,arCOG07581@2157|Archaea,arCOG07781@2157|Archaea,arCOG10187@2157|Archaea,2XVFT@28890|Euryarchaeota,23V0T@183963|Halobacteria	183963|Halobacteria	P	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,Malectin,PKD,REJ
SRR25158347_k127_3274839_6	500153.JOEK01000024_gene8	7.077e-08	66.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1349,GSDH,PKD,ThuA
SRR25158347_k127_3274839_2	645991.Sgly_2998	4.05e-38	166.0	COG2247@1|root,COG3858@1|root,COG2247@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,26091@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
SRR25158347_k127_3274839_3	1089455.MOPEL_080_00590	1.116e-20	96.0	COG0239@1|root,COG0239@2|Bacteria,2HSUA@201174|Actinobacteria,4F799@85018|Dermatophilaceae	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	-	-	-	-	-	-	-	-	-	-	-	-	CRCB
SRR25158347_k127_3274839_5	1240349.ANGC01000015_gene714	3.01e-08	64.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,4G3CM@85025|Nocardiaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158347_k127_3274839_1	390989.JOEG01000001_gene5220	1.382e-131	437.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4D8NU@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158347_k127_3286173_3	1469245.JFBG01000023_gene1264	1.478e-75	267.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,1RNCV@1236|Gammaproteobacteria,1WW63@135613|Chromatiales	135613|Chromatiales	J	tRNA modifying enzyme	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158347_k127_3286173_0	675635.Psed_1304	7.934e-244	775.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpV	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K12954,ko:K12956,ko:K17686,ko:K21887	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158347_k127_3286173_11	1120948.KB903229_gene4950	6.209e-16	81.0	COG2608@1|root,COG2608@2|Bacteria,2GXF6@201174|Actinobacteria,4EDAJ@85010|Pseudonocardiales	201174|Actinobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR25158347_k127_3286173_6	1229203.KI301992_gene2722	2.555e-31	130.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,3UXH4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158347_k127_3286173_4	1313172.YM304_40420	9.112e-60	215.0	COG2188@1|root,COG2188@2|Bacteria,2HF90@201174|Actinobacteria,4CNBB@84992|Acidimicrobiia	84992|Acidimicrobiia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158347_k127_3286173_5	1184607.AUCHE_20_00050	6.053e-53	199.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4F80H@85018|Dermatophilaceae	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158347_k127_3286173_9	309801.trd_A0835	9.129e-21	108.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,27YN5@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158347_k127_3286173_2	1313172.YM304_39870	4.43e-162	525.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4CMVK@84992|Acidimicrobiia	84992|Acidimicrobiia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158347_k127_3286173_7	1347087.CBYO010000022_gene3461	2.747e-29	123.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HH9B@91061|Bacilli	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158347_k127_3286173_8	1229780.BN381_350095	2.626e-24	113.0	COG0526@1|root,COG0526@2|Bacteria,2H8ZP@201174|Actinobacteria	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3286173_10	28444.JODQ01000002_gene4528	9.495e-17	88.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4EJ9C@85012|Streptosporangiales	201174|Actinobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158347_k127_3286173_1	1229780.BN381_430008	1.169e-170	549.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158347_k127_3286173_12	526225.Gobs_3390	6.235e-05	53.0	2CFUM@1|root,32S2H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3289619_1	1120936.KB907215_gene3950	6.901e-13	78.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
SRR25158347_k127_3289619_0	1122138.AQUZ01000044_gene4502	7.998e-96	323.0	COG0701@1|root,COG0701@2|Bacteria,2HZBT@201174|Actinobacteria	201174|Actinobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
SRR25158347_k127_3299837_0	644283.Micau_0944	9.267e-231	721.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4D8NB@85008|Micromonosporales	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158347_k127_3299837_3	1206743.BAGM01000101_gene2583	2.564e-53	205.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,4G0CF@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158347_k127_3299837_5	404589.Anae109_1019	1.577e-37	154.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158347_k127_3299837_4	287986.DV20_04745	4.83e-43	165.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4E3G4@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158347_k127_3299837_1	1463885.KL578449_gene9307	3.931e-146	471.0	COG0435@1|root,COG0435@2|Bacteria,2GIXK@201174|Actinobacteria	201174|Actinobacteria	O	Glutathione S-transferase	yqjG	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
SRR25158347_k127_3299837_6	1089549.AZUQ01000001_gene2418	1.94e-30	130.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	gpmB	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158347_k127_3299837_2	235985.BBPN01000006_gene3586	5.942e-92	307.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,2NF6J@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_3301965_5	1463917.JODC01000003_gene5844	5.443e-15	78.0	COG0346@1|root,COG0346@2|Bacteria,2IRQX@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_3301965_0	526225.Gobs_0648	4.03e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158347_k127_3301965_3	882083.SacmaDRAFT_3107	2.198e-23	113.0	2DU40@1|root,33NV5@2|Bacteria,2GTWE@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR25158347_k127_3301965_4	136273.GY22_14975	4.41e-16	82.0	2DRQB@1|root,33CKR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3301965_1	1380393.JHVP01000004_gene703	6.184e-28	119.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158347_k127_3301965_2	526225.Gobs_2572	2.688e-25	123.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ETGG@85013|Frankiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Guanylate_cyc,NB-ARC,Trans_reg_C
SRR25158347_k127_3302122_11	1078020.KEK_16328	1.487e-08	56.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,239X1@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158347_k127_3302122_0	1289387.AUKW01000010_gene1117	7.18e-184	590.0	COG3011@1|root,COG3011@2|Bacteria,2GMSU@201174|Actinobacteria	201174|Actinobacteria	S	Lipase maturation factor	LMF	-	-	-	-	-	-	-	-	-	-	-	LMF1
SRR25158347_k127_3302122_9	1349820.M707_15945	2.881e-10	74.0	COG2258@1|root,COG2258@2|Bacteria,2IH5Z@201174|Actinobacteria	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3302122_2	1122622.ATWJ01000010_gene1305	5.648e-91	332.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
SRR25158347_k127_3302122_4	1122622.ATWJ01000010_gene1306	7.637e-32	131.0	2BCV5@1|root,326FU@2|Bacteria,2HBXJ@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3302122_7	1169143.KB911049_gene5642	5.658e-13	76.0	COG4454@1|root,COG4454@2|Bacteria,1N1PE@1224|Proteobacteria,2W9JN@28216|Betaproteobacteria,1K7FT@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158347_k127_3302122_1	926560.KE387023_gene1422	8.662e-162	527.0	COG0659@1|root,COG0659@2|Bacteria,1WM9X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158347_k127_3302122_5	1476876.JOJO01000067_gene3066	1.474e-26	113.0	COG0640@1|root,COG0640@2|Bacteria,2IKK2@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158347_k127_3302122_6	570268.ANBB01000002_gene360	9.243e-24	104.0	COG0748@1|root,COG0748@2|Bacteria,2I5ZU@201174|Actinobacteria	201174|Actinobacteria	P	Protein of unknown function (DUF2470)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2470
SRR25158347_k127_3302122_10	1173024.KI912148_gene3134	1.233e-09	68.0	2A293@1|root,30QJU@2|Bacteria,1G5ZB@1117|Cyanobacteria,1JGVE@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3302122_3	1169161.KB897716_gene5731	9.242e-38	163.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
SRR25158347_k127_3302122_8	551789.ATVJ01000001_gene1045	2.83e-12	80.0	COG1520@1|root,COG1520@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
SRR25158347_k127_3309528_16	1381751.JAJB01000020_gene1857	0.0004101	50.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4F964@85019|Brevibacteriaceae	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158347_k127_3309528_12	268739.Nmlp_2824	9.881e-48	183.0	COG4221@1|root,arCOG01265@2157|Archaea,2XT0E@28890|Euryarchaeota,23U0H@183963|Halobacteria	183963|Halobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_3309528_5	1122599.AUGR01000005_gene1973	1.429e-142	467.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XK8Z@135619|Oceanospirillales	135619|Oceanospirillales	E	Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158347_k127_3309528_6	1380347.JNII01000006_gene1593	1.033e-122	413.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158347_k127_3309528_0	1043493.BBLU01000016_gene1503	1.579e-182	602.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158347_k127_3309528_7	1068978.AMETH_4865	3.995e-98	327.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,4DYKN@85010|Pseudonocardiales	201174|Actinobacteria	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158347_k127_3309528_9	1035308.AQYY01000001_gene1649	5.262e-86	301.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,263WK@186807|Peptococcaceae	186801|Clostridia	H	pfkB family carbohydrate kinase	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158347_k127_3309528_4	35754.JNYJ01000045_gene4023	2.134e-147	494.0	COG2213@1|root,COG2213@2|Bacteria,2GMYR@201174|Actinobacteria,4DBE6@85008|Micromonosporales	201174|Actinobacteria	G	phosphotransferase system	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158347_k127_3309528_14	1246448.ANAZ01000013_gene1576	3.063e-34	135.0	COG2213@1|root,COG2213@2|Bacteria,2IRUU@201174|Actinobacteria,4EK2S@85012|Streptosporangiales	201174|Actinobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.197	ko:K02799	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_IIB
SRR25158347_k127_3309528_13	1122994.AUFR01000029_gene490	2.546e-46	173.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,2GMYR@201174|Actinobacteria,4DPTM@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphotransferase system, EIIC	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158347_k127_3309528_3	1089545.KB913037_gene18	1.34e-147	474.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DXRH@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_3309528_15	234621.RER_39600	7.868e-19	95.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4G2ZC@85025|Nocardiaceae	201174|Actinobacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRR25158347_k127_3309528_1	1449346.JQMO01000003_gene2762	3.342e-179	576.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,2M23V@2063|Kitasatospora	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158347_k127_3309528_2	1276756.AUEX01000008_gene3183	6.718e-148	487.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,2VII5@28216|Betaproteobacteria,4AC9X@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
SRR25158347_k127_3309528_11	710111.FraQA3DRAFT_4233	1.711e-63	231.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria,4ESKD@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_3309528_10	35754.JNYJ01000029_gene9510	6.549e-75	278.0	COG4585@1|root,COG4585@2|Bacteria,2GMMU@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158347_k127_3309528_8	1169152.AXVD01000023_gene3256	1.03e-89	308.0	COG2021@1|root,COG2021@2|Bacteria,2HIEG@201174|Actinobacteria,4G3VG@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_3331364_7	926569.ANT_01210	1.929e-53	193.0	COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158347_k127_3331364_1	1089545.KB913037_gene6391	4.826e-222	716.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DXAG@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158347_k127_3331364_9	43354.JOIJ01000004_gene3548	4.305e-43	174.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E2JM@85010|Pseudonocardiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158347_k127_3331364_6	1313172.YM304_25320	2.491e-61	241.0	COG4630@1|root,COG4630@2|Bacteria,2I33J@201174|Actinobacteria	201174|Actinobacteria	F	Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158347_k127_3331364_5	196162.Noca_1631	1.002e-115	396.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158347_k127_3331364_3	926550.CLDAP_10970	5.935e-156	497.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158347_k127_3331364_4	1167006.UWK_01323	3.975e-143	466.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_3331364_2	1121439.dsat_2229	5.944e-212	668.0	COG0031@1|root,COG0031@2|Bacteria,1QQKZ@1224|Proteobacteria,42PVJ@68525|delta/epsilon subdivisions,2WKKY@28221|Deltaproteobacteria,2MEAE@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	PALP
SRR25158347_k127_3331364_11	1121106.JQKB01000018_gene4928	8.174e-20	102.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,2JR4W@204441|Rhodospirillales	204441|Rhodospirillales	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158347_k127_3331364_8	1187851.A33M_3519	8.158e-48	180.0	COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2TS73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
SRR25158347_k127_3331364_0	521045.Kole_2082	4.517e-252	799.0	COG1529@1|root,COG1529@2|Bacteria,2GCJ6@200918|Thermotogae	200918|Thermotogae	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158347_k127_3331364_10	452637.Oter_2190	1.282e-21	97.0	COG1472@1|root,COG1472@2|Bacteria,46UPF@74201|Verrucomicrobia,3K900@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158347_k127_3413094_17	929712.KI912613_gene3371	4.642e-20	93.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4CSI7@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158347_k127_3413094_18	1380347.JNII01000007_gene731	1.514e-19	96.0	2C9IE@1|root,32UBS@2|Bacteria,2INT4@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158347_k127_3413094_11	1137269.AZWL01000005_gene2235	2.883e-27	126.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158347_k127_3413094_10	1713.JOFV01000004_gene3311	2.952e-32	136.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3413094_5	1242864.D187_009943	1.128e-50	188.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158347_k127_3413094_9	1089544.KB912942_gene1687	9.762e-37	159.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXBN@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_3413094_15	1089544.KB912942_gene1686	9.53e-24	101.0	COG0842@1|root,COG0842@2|Bacteria,2H2PR@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158347_k127_3413094_1	345341.KUTG_04564	1.958e-107	359.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4DX3X@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_3413094_4	1211815.CBYP010000026_gene1175	6.949e-65	240.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4ETC8@85013|Frankiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158347_k127_3413094_6	1122138.AQUZ01000036_gene5466	1.261e-47	190.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3413094_7	1385518.N798_01345	4.497e-47	178.0	2F7D1@1|root,33ZU2@2|Bacteria,2ITDT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3413094_8	1122622.ATWJ01000013_gene163	5.51e-40	160.0	2B2T8@1|root,31VDK@2|Bacteria,2GVG1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3413094_3	118168.MC7420_26	1.154e-71	262.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G35U@1117|Cyanobacteria,1H78M@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF4118,GAF_3,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_3413094_2	533240.CRC_01021	3.246e-103	348.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1HJ2V@1161|Nostocales	1117|Cyanobacteria	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158347_k127_3413094_12	880073.Calab_2337	1.177e-26	124.0	COG3288@1|root,COG3288@2|Bacteria,2NRJW@2323|unclassified Bacteria	2|Bacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158347_k127_3413094_0	1236542.BALM01000011_gene3910	1.349e-129	435.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,2Q93R@267890|Shewanellaceae	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158347_k127_3413094_14	469371.Tbis_3576	5.97e-24	109.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DXS2@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3413094_13	345341.KUTG_09771	1.486e-25	122.0	2B2WB@1|root,31VGW@2|Bacteria,2GY45@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3413094_16	345341.KUTG_00558	2.936e-23	106.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4E6H3@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158347_k127_3413094_19	379731.PST_0237	2.897e-06	49.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,1RRFQ@1236|Gammaproteobacteria,1YZYC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	D	Arsenical pump-driving ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
SRR25158347_k127_3415831_4	1120972.AUMH01000007_gene1721	3.515e-60	229.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158347_k127_3415831_8	448385.sce7897	1.678e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YVKS@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3415831_11	1122218.KB893669_gene1582	0.0003948	51.0	COG5662@1|root,COG5662@2|Bacteria,1N8DF@1224|Proteobacteria,2UGV4@28211|Alphaproteobacteria,1JYS0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3415831_10	42256.RradSPS_0661	1.836e-19	96.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8
SRR25158347_k127_3415831_1	1463821.JOGR01000011_gene2076	9.164e-121	397.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4EXVQ@85014|Glycomycetales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158347_k127_3415831_6	326424.FRAAL6873	3.542e-41	154.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4ET42@85013|Frankiales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158347_k127_3415831_3	1122182.KB903815_gene1404	2.306e-75	269.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4D9CS@85008|Micromonosporales	201174|Actinobacteria	M	Ami_3	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
SRR25158347_k127_3415831_7	67373.JOBF01000004_gene825	1.046e-35	148.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_3415831_0	471857.Svir_39710	3.187e-149	487.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4E0UW@85010|Pseudonocardiales	201174|Actinobacteria	EK	PFAM Aminotransferase class I and II	avtA	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158347_k127_3415831_2	1120949.KB903297_gene5629	5.115e-89	302.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4DA6S@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158347_k127_3415831_5	1463856.JOHY01000012_gene3216	1.25e-47	191.0	COG1011@1|root,COG1011@2|Bacteria,2GPJ4@201174|Actinobacteria	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase,Hydrolase_like
SRR25158347_k127_3415831_9	1336243.JAEA01000005_gene1291	4.901e-26	114.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2TU68@28211|Alphaproteobacteria,1JRKP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158347_k127_350421_0	1380347.JNII01000005_gene3745	4.285e-45	186.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CBM_35,F5_F8_type_C,Pectate_lyase_3
SRR25158347_k127_3524635_10	1123073.KB899241_gene1823	1.156e-25	115.0	COG3296@1|root,COG3296@2|Bacteria,1N8TC@1224|Proteobacteria,1SEZY@1236|Gammaproteobacteria,1X76D@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158347_k127_3524635_0	710111.FraQA3DRAFT_3806	1.268e-237	744.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4ERBR@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158347_k127_3524635_15	656024.FsymDg_2329	0.0005785	52.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158347_k127_3524635_13	1121859.KB890738_gene3099	6.792e-18	96.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,47Q85@768503|Cytophagia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
SRR25158347_k127_3524635_4	2002.JOEQ01000010_gene6337	4.165e-114	389.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4EHJH@85012|Streptosporangiales	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158347_k127_3524635_11	134676.ACPL_868	1.155e-23	117.0	2DHRC@1|root,32U9K@2|Bacteria,2II2K@201174|Actinobacteria,4DM9E@85008|Micromonosporales	201174|Actinobacteria	S	Family of unknown function (DUF5319)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5319
SRR25158347_k127_3524635_1	367299.JOEE01000004_gene994	2.659e-148	499.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4FHA0@85021|Intrasporangiaceae	201174|Actinobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158347_k127_3524635_9	448385.sce1548	2.851e-33	141.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,42PIY@68525|delta/epsilon subdivisions,2X81Z@28221|Deltaproteobacteria,2YXIU@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_3524635_8	871963.Desdi_3224	2.715e-34	153.0	COG2247@1|root,COG3858@1|root,COG2247@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,26091@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
SRR25158347_k127_3524635_7	1173026.Glo7428_3607	5.108e-39	168.0	COG4124@1|root,COG4124@2|Bacteria,1GD5A@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3524635_5	1048834.TC41_2616	7.034e-50	194.0	COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HCQJ@91061|Bacilli,27840@186823|Alicyclobacillaceae	91061|Bacilli	M	Glycosyl transferase family group 2	epsG	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158347_k127_3524635_3	1416759.AYMR01000012_gene2015	4.302e-122	402.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4FP4J@85023|Microbacteriaceae	201174|Actinobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158347_k127_3524635_14	1424334.W822_10785	8.033e-11	74.0	COG0438@1|root,COG0438@2|Bacteria,1NVAT@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158347_k127_3524635_12	1380354.JIAN01000006_gene1022	7.674e-21	108.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_3524635_6	644968.DFW101_3053	2.966e-40	161.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,2M7SU@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158347_k127_3524635_2	926569.ANT_09960	3.174e-123	402.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158347_k127_3526322_0	1451189.CFAL_02400	1.274e-117	391.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,22K2J@1653|Corynebacteriaceae	201174|Actinobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158347_k127_3526322_1	1121468.AUBR01000027_gene2877	1.258e-42	172.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,42FS4@68295|Thermoanaerobacterales	186801|Clostridia	D	Stage II sporulation D domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
SRR25158347_k127_3542400_5	1286631.X805_02700	1.106e-27	121.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,1KKM9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglycerate mutase	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158347_k127_3542400_7	378753.KRH_11380	1.706e-25	119.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,1W9TZ@1268|Micrococcaceae	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158347_k127_3542400_8	644966.Tmar_2199	3.897e-20	104.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,3WD9K@538999|Clostridiales incertae sedis	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158347_k127_3542400_4	883081.HMPREF9698_00097	2.951e-44	169.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,27G7J@186828|Carnobacteriaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158347_k127_3542400_0	1229780.BN381_10220	7.315e-117	408.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,3UX9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158347_k127_3542400_3	471853.Bcav_2258	1.462e-82	288.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	MA20_27720	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_3542400_6	469383.Cwoe_2650	1.504e-25	113.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3542400_9	981369.JQMJ01000004_gene482	1.174e-07	59.0	COG3620@1|root,COG3620@2|Bacteria,2IKRP@201174|Actinobacteria,2NK6R@228398|Streptacidiphilus	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158347_k127_3542400_2	67356.KL575585_gene8311	1.892e-84	302.0	COG0627@1|root,COG0627@2|Bacteria,2H9D2@201174|Actinobacteria	201174|Actinobacteria	M	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158347_k127_3542400_1	1283287.KB822575_gene633	3.746e-108	357.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DNUY@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158347_k127_3551780_3	1231336.L248_1046	2.306e-43	164.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,3F58M@33958|Lactobacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	phnB	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158347_k127_3551780_1	1137268.AZXF01000011_gene3652	3.328e-59	222.0	COG3639@1|root,COG3639@2|Bacteria,2IAPI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type phosphate phosphonate transport system permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158347_k127_3551780_0	1146883.BLASA_2690	2.479e-111	369.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4ES2H@85013|Frankiales	201174|Actinobacteria	F	SMART Metal-dependent phosphohydrolase, HD region	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158347_k127_3551780_2	358823.DF19_33470	1.49e-46	177.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158347_k127_3551780_4	1288079.AUKN01000021_gene2385	4.285e-30	131.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria	201174|Actinobacteria	O	PFAM globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158347_k127_3553403_5	2074.JNYD01000015_gene4502	5.46e-06	48.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E16G@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_3553403_4	1043493.BBLU01000008_gene458	2.047e-11	74.0	2DX9S@1|root,3441J@2|Bacteria,2IT0X@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158347_k127_3553403_3	1298863.AUEP01000022_gene1862	1.024e-31	134.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria,4DV53@85009|Propionibacteriales	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158347_k127_3553403_0	935866.JAER01000010_gene4041	5.171e-153	522.0	COG2355@1|root,COG2355@2|Bacteria,2HZ6F@201174|Actinobacteria,4DPCY@85009|Propionibacteriales	201174|Actinobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3553403_2	1120960.ATXG01000002_gene2944	1.735e-57	213.0	COG3910@1|root,COG3910@2|Bacteria,2GNJ2@201174|Actinobacteria,4FR6V@85023|Microbacteriaceae	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23,ABC_tran
SRR25158347_k127_3553403_1	1089550.ATTH01000001_gene1477	4.314e-105	375.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
SRR25158347_k127_3553403_6	1298863.AUEP01000013_gene4054	2.119e-05	49.0	COG3173@1|root,COG3173@2|Bacteria,2IA48@201174|Actinobacteria,4DR9I@85009|Propionibacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_3650413_6	649638.Trad_2776	5.483e-35	145.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
SRR25158347_k127_3650413_0	358823.DF19_31400	9.789e-245	773.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158347_k127_3650413_2	1283299.AUKG01000002_gene5072	3.262e-92	312.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CRGJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_3650413_7	926560.KE387023_gene3186	6.812e-09	66.0	COG4392@1|root,COG4392@2|Bacteria,1WNCD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158347_k127_3650413_5	1121945.ATXS01000001_gene2030	2.294e-45	186.0	COG1296@1|root,arCOG04452@2157|Archaea,2XWP8@28890|Euryarchaeota,23VF2@183963|Halobacteria	183963|Halobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158347_k127_3650413_4	580340.Tlie_0063	1.45e-75	278.0	COG1322@1|root,COG1322@2|Bacteria,3T9XJ@508458|Synergistetes	508458|Synergistetes	S	PFAM RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158347_k127_3650413_1	608506.COB47_0943	4.27e-171	551.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158347_k127_3650413_3	28444.JODQ01000001_gene2596	7.24e-79	293.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158347_k127_3676938_4	1192034.CAP_7313	3.58e-86	311.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
SRR25158347_k127_3676938_8	479434.Sthe_2638	1.373e-36	158.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi,27Z83@189775|Thermomicrobia	189775|Thermomicrobia	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158347_k127_3676938_6	526225.Gobs_0783	5.283e-66	244.0	COG0300@1|root,COG0300@2|Bacteria,2I2RM@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR25158347_k127_3676938_2	1089545.KB913037_gene8875	4.883e-153	493.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3676938_7	35754.JNYJ01000036_gene3658	3.875e-62	233.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DDFA@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158347_k127_3676938_5	404589.Anae109_4241	1.466e-73	253.0	COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,43AKT@68525|delta/epsilon subdivisions,2X60V@28221|Deltaproteobacteria,2Z23B@29|Myxococcales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158347_k127_3676938_3	1298863.AUEP01000011_gene626	1.859e-94	324.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,4DUVW@85009|Propionibacteriales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158347_k127_3676938_1	2074.JNYD01000026_gene649	9.757e-154	517.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E16G@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_3676938_0	1306990.BARG01000024_gene2594	7.183e-164	549.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_3676938_9	1238182.C882_0313	1.26e-23	102.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,2JRUI@204441|Rhodospirillales	204441|Rhodospirillales	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158347_k127_3677571_6	935866.JAER01000012_gene3501	2.344e-123	406.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4DP1E@85009|Propionibacteriales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158347_k127_3677571_43	1449976.KALB_3368	9.095e-21	97.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria,4E4AC@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158347_k127_3677571_10	1382356.JQMP01000003_gene2585	1.694e-112	373.0	COG3892@1|root,COG3892@2|Bacteria,2G87A@200795|Chloroflexi,27Z2I@189775|Thermomicrobia	189775|Thermomicrobia	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2090
SRR25158347_k127_3677571_32	543632.JOJL01000035_gene5070	1.976e-43	169.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158347_k127_3677571_18	469371.Tbis_0649	1.381e-83	282.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DZWV@85010|Pseudonocardiales	201174|Actinobacteria	T	Response regulator receiver	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_3677571_21	1048339.KB913029_gene2815	2.71e-76	272.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4ESG9@85013|Frankiales	201174|Actinobacteria	T	signal transduction histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
SRR25158347_k127_3677571_34	1121946.AUAX01000003_gene1474	1.278e-38	160.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4DAQE@85008|Micromonosporales	201174|Actinobacteria	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
SRR25158347_k127_3677571_27	459495.SPLC1_S082680	1.507e-60	227.0	COG0477@1|root,COG2814@2|Bacteria,1G1MW@1117|Cyanobacteria,1HHW0@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_3677571_48	1120949.KB903315_gene169	9.958e-11	71.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria,4DHT8@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158347_k127_3677571_20	526225.Gobs_0783	2.143e-81	281.0	COG0300@1|root,COG0300@2|Bacteria,2I2RM@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR25158347_k127_3677571_2	936550.HMPREF1492_1415	3.073e-162	523.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CUX7@84998|Coriobacteriia	84998|Coriobacteriia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158347_k127_3677571_30	290397.Adeh_3524	1.424e-56	228.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
SRR25158347_k127_3677571_8	1121346.KB899831_gene738	6.893e-122	404.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,26SBN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
SRR25158347_k127_3677571_31	1125712.HMPREF1316_0830	1.014e-47	177.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CVVV@84998|Coriobacteriia	84998|Coriobacteriia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158347_k127_3677571_4	479435.Kfla_5445	3.727e-140	466.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4DS4B@85009|Propionibacteriales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158347_k127_3677571_3	2002.JOEQ01000005_gene3775	3.639e-154	501.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4EMIT@85012|Streptosporangiales	201174|Actinobacteria	C	HI0933-like protein	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
SRR25158347_k127_3677571_14	222534.KB893714_gene1641	9.984e-104	349.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4ERID@85013|Frankiales	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158347_k127_3677571_38	196162.Noca_4889	3.336e-30	123.0	COG2044@1|root,COG2044@2|Bacteria,2IHT6@201174|Actinobacteria	2|Bacteria	S	DsrE/DsrF-like family	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
SRR25158347_k127_3677571_25	196162.Noca_3017	1.14e-63	235.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4DPSP@85009|Propionibacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158347_k127_3677571_41	35754.JNYJ01000012_gene1012	4.524e-22	103.0	COG1595@1|root,COG1595@2|Bacteria,2HWJY@201174|Actinobacteria,4DJ5F@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3677571_11	1304865.JAGF01000001_gene3475	6.854e-110	374.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4F1PT@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM ABC transporter related	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158347_k127_3677571_9	1268303.RHODMAR_2895	1.065e-118	388.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4G8R8@85025|Nocardiaceae	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_3677571_16	1137271.AZUM01000002_gene2147	1.003e-99	334.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4E0ZS@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_3677571_17	1123251.ATWM01000002_gene413	4.608e-92	325.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4FFXG@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
SRR25158347_k127_3677571_36	1120949.KB903339_gene8026	3.797e-33	138.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4DIF2@85008|Micromonosporales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158347_k127_3677571_40	351607.Acel_2106	1.808e-22	105.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4ET89@85013|Frankiales	201174|Actinobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158347_k127_3677571_24	570268.ANBB01000057_gene4145	1.033e-63	234.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4EGK0@85012|Streptosporangiales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158347_k127_3677571_7	1150599.MPHLEI_17952	2.916e-122	405.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,234J4@1762|Mycobacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158347_k127_3677571_15	1147.D082_28780	2.667e-101	361.0	COG0744@1|root,COG0744@2|Bacteria,1G1XF@1117|Cyanobacteria,1H4I4@1142|Synechocystis	1117|Cyanobacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_3677571_51	1168059.KB899087_gene1061	1.566e-05	52.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158347_k127_3677571_47	710696.Intca_0372	5.846e-14	76.0	2EGTM@1|root,33AJR@2|Bacteria,2GWY1@201174|Actinobacteria,4FHPK@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3677571_5	518766.Rmar_2667	2.312e-138	461.0	COG0475@1|root,COG0569@1|root,COG1762@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,4NFPE@976|Bacteroidetes	976|Bacteroidetes	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158347_k127_3677571_22	1246995.AFR_11450	4.401e-76	261.0	COG0745@1|root,COG0745@2|Bacteria,2GMZK@201174|Actinobacteria	201174|Actinobacteria	T	regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_3677571_28	443906.CMM_0699	4.827e-58	226.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,4FRHM@85023|Microbacteriaceae	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_3677571_42	1385519.N801_07185	8.259e-22	104.0	COG1320@1|root,COG1320@2|Bacteria,2IQXD@201174|Actinobacteria,4FHDS@85021|Intrasporangiaceae	201174|Actinobacteria	P	cation proton antiporter	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
SRR25158347_k127_3677571_49	1313172.YM304_38060	6.707e-10	70.0	COG2212@1|root,COG2212@2|Bacteria	2|Bacteria	P	antiporter activity	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
SRR25158347_k127_3677571_45	1122611.KB903939_gene603	7.198e-19	93.0	COG1863@1|root,COG1863@2|Bacteria,2IQD6@201174|Actinobacteria,4EKPF@85012|Streptosporangiales	201174|Actinobacteria	P	Na+/H+ ion antiporter subunit	mrpE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
SRR25158347_k127_3677571_1	1229780.BN381_150134	5.556e-165	533.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,3UX2B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CP	Proton-conducting membrane transporter	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158347_k127_3677571_37	1380354.JIAN01000005_gene2118	7e-33	139.0	COG1006@1|root,COG1006@2|Bacteria,2ISBC@201174|Actinobacteria,4F2F2@85016|Cellulomonadaceae	201174|Actinobacteria	P	PFAM NADH-ubiquinone oxidoreductase chain 4L	mrpC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
SRR25158347_k127_3677571_33	1229781.C272_05164	2.806e-40	153.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4F8DI@85019|Brevibacteriaceae	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	mrpA/mrpB	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_3677571_0	263358.VAB18032_19965	3.287e-182	596.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4D9ZF@85008|Micromonosporales	201174|Actinobacteria	CP	Na H antiporter	mrpA/mrpB	-	1.6.5.3	ko:K00341,ko:K05565,ko:K14086	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_3677571_52	882086.SacxiDRAFT_2847	2.102e-05	54.0	COG0589@1|root,COG0589@2|Bacteria,2IP0V@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158347_k127_3677571_44	710111.FraQA3DRAFT_6236	1.455e-19	103.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4ERNN@85013|Frankiales	201174|Actinobacteria	T	Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR25158347_k127_3677571_35	278957.ABEA03000085_gene2589	3.528e-37	160.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158347_k127_3677571_26	1108045.GORHZ_141_00490	5.17e-63	229.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4GD7E@85026|Gordoniaceae	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158347_k127_3677571_13	1449069.JMLO01000029_gene4935	1.338e-108	367.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4FX3F@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_3677571_12	1120948.KB903243_gene2518	4.203e-109	368.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,4E2RN@85010|Pseudonocardiales	201174|Actinobacteria	Q	Male sterility protein	acrA1_1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SRR25158347_k127_3677571_50	935866.JAER01000019_gene4002	7.13e-10	68.0	COG1652@1|root,COG1652@2|Bacteria,2GWK7@201174|Actinobacteria,4DSN3@85009|Propionibacteriales	201174|Actinobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158347_k127_3677571_46	1463909.KL585959_gene958	8.667e-18	93.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158347_k127_3677571_19	1122182.KB903818_gene1985	5.848e-82	284.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4D9AB@85008|Micromonosporales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158347_k127_3677571_29	222534.KB893725_gene285	2.818e-57	214.0	COG1896@1|root,COG1896@2|Bacteria,2GN7A@201174|Actinobacteria	201174|Actinobacteria	S	of HD superfamily	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
SRR25158347_k127_3677571_39	452637.Oter_0968	2.048e-27	125.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	rimL	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158347_k127_3677571_23	1121106.JQKB01000007_gene1085	1.102e-74	255.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2JQPF@204441|Rhodospirillales	204441|Rhodospirillales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158347_k127_3679101_23	471852.Tcur_2095	5.518e-12	72.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4EG5V@85012|Streptosporangiales	201174|Actinobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158347_k127_3679101_5	1313172.YM304_38610	1.44e-86	292.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CNQN@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_3679101_8	1313172.YM304_38600	3.575e-56	215.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_3679101_20	66875.JODY01000007_gene2585	1.312e-23	115.0	COG0308@1|root,COG0308@2|Bacteria,2GK29@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3679101_26	1380393.JHVP01000003_gene910	4.585e-06	57.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158347_k127_3679101_19	670487.Ocepr_2208	3.193e-24	118.0	COG0682@1|root,COG0682@2|Bacteria,1WJCB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158347_k127_3679101_15	1120985.AUMI01000014_gene861	2.23e-36	153.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4H1XM@909932|Negativicutes	909932|Negativicutes	D	Peptidase M23	envC_1	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_3679101_17	446462.Amir_6064	2.851e-33	141.0	COG0500@1|root,COG2226@2|Bacteria,2HIHA@201174|Actinobacteria,4DY0M@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158347_k127_3679101_16	1134445.AJJM01000028_gene4469	5.958e-35	147.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158347_k127_3679101_25	1463903.JOIZ01000008_gene4396	1.867e-07	63.0	COG3917@1|root,COG3917@2|Bacteria,2IGGE@201174|Actinobacteria	201174|Actinobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158347_k127_3679101_1	42256.RradSPS_2144	2.863e-151	488.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158347_k127_3679101_13	134676.ACPL_2273	1.404e-39	165.0	COG4251@1|root,COG4251@2|Bacteria,2IEQC@201174|Actinobacteria,4DICH@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_4
SRR25158347_k127_3679101_18	243230.DR_2165	5.55e-25	109.0	COG2151@1|root,COG2151@2|Bacteria,1WK4T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2151 metal-sulfur cluster biosynthetic protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158347_k127_3679101_11	298655.KI912267_gene7007	1.855e-40	154.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4ESKF@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158347_k127_3679101_2	765420.OSCT_1487	1.001e-122	406.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,3766K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158347_k127_3679101_4	1394178.AWOO02000020_gene7502	7.43e-94	316.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4EGEE@85012|Streptosporangiales	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158347_k127_3679101_7	309801.trd_0379	7.603e-69	260.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158347_k127_3679101_0	1283283.ATXA01000001_gene930	5.314e-223	711.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4ERKY@85013|Frankiales	201174|Actinobacteria	O	TIGRFAM FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158347_k127_3679101_21	548476.cauri_1215	1.721e-23	113.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,22KCM@1653|Corynebacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR25158347_k127_3679101_22	864051.BurJ1DRAFT_1622	6.972e-22	106.0	COG0745@1|root,COG0745@2|Bacteria,1R52E@1224|Proteobacteria,2VZQH@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_3679101_9	867903.ThesuDRAFT_01009	1.34e-52	197.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_3679101_10	1122622.ATWJ01000010_gene1241	1.303e-47	197.0	COG1404@1|root,COG2385@1|root,COG1404@2|Bacteria,COG2385@2|Bacteria,2I7DE@201174|Actinobacteria,4FFA3@85021|Intrasporangiaceae	201174|Actinobacteria	O	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,CarboxypepD_reg,Kelch_1,Malectin,Peptidase_S8
SRR25158347_k127_3679101_24	543632.JOJL01000026_gene2428	7.051e-09	69.0	COG2227@1|root,COG2227@2|Bacteria,2GTJX@201174|Actinobacteria,4DF15@85008|Micromonosporales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158347_k127_3679101_3	324602.Caur_0824	1.579e-116	408.0	COG0507@1|root,COG0507@2|Bacteria,2G626@200795|Chloroflexi,376JS@32061|Chloroflexia	32061|Chloroflexia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158347_k127_3679101_27	1323361.JPOC01000008_gene3446	0.0001283	54.0	2AQPD@1|root,31FWY@2|Bacteria,2HJK0@201174|Actinobacteria,4G6YZ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3679101_12	929712.KI912613_gene1527	2.101e-40	163.0	COG3268@1|root,COG3268@2|Bacteria,2GMKU@201174|Actinobacteria,4CSJP@84995|Rubrobacteria	84995|Rubrobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158347_k127_3679101_14	1394178.AWOO02000007_gene3167	1.729e-37	148.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4EJ5G@85012|Streptosporangiales	201174|Actinobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158347_k127_3679101_6	196162.Noca_1778	3.94e-78	273.0	COG4677@1|root,COG4677@2|Bacteria,2GNHF@201174|Actinobacteria	201174|Actinobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158347_k127_3681097_0	926554.KI912633_gene3890	7.327e-88	299.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158347_k127_3681097_1	1048339.KB913029_gene1641	5.599e-58	219.0	COG2270@1|root,COG2270@2|Bacteria,2GK5A@201174|Actinobacteria,4ERM2@85013|Frankiales	201174|Actinobacteria	S	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_3681097_2	58123.JOFJ01000002_gene2352	2.427e-23	103.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR25158347_k127_3685490_0	429009.Adeg_1980	4.936e-145	476.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
SRR25158347_k127_3685490_1	1123320.KB889675_gene3982	8.534e-65	232.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_3685490_2	1713.JOFV01000010_gene1135	1.318e-33	138.0	2AWFS@1|root,31NC1@2|Bacteria,2IMS0@201174|Actinobacteria,4F1EB@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3685490_3	253839.SSNG_05492	3.367e-26	109.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158347_k127_3685548_6	68223.JNZY01000035_gene3422	3.142e-47	176.0	COG1435@1|root,COG1435@2|Bacteria,2GP1W@201174|Actinobacteria	201174|Actinobacteria	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158347_k127_3685548_0	1297742.A176_04648	1.38e-248	779.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42NSP@68525|delta/epsilon subdivisions,2WMAD@28221|Deltaproteobacteria,2YTY4@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRR25158347_k127_3685548_12	1449050.JNLE01000003_gene2627	0.0001009	55.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,36EUU@31979|Clostridiaceae	186801|Clostridia	E	family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158347_k127_3685548_5	521003.COLINT_03432	1.069e-71	266.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CUJQ@84998|Coriobacteriia	84998|Coriobacteriia	E	pathway, signal sequence	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158347_k127_3685548_10	479433.Caci_5605	6.385e-10	63.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158347_k127_3685548_7	251221.35212595	1.033e-23	115.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48,Peptidase_M56
SRR25158347_k127_3685548_8	1521187.JPIM01000013_gene2754	5.957e-21	97.0	COG3682@1|root,COG3682@2|Bacteria,2GAQU@200795|Chloroflexi,37733@32061|Chloroflexia	32061|Chloroflexia	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158347_k127_3685548_1	1313172.YM304_21740	2.717e-152	493.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4CP5H@84992|Acidimicrobiia	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158347_k127_3685548_2	1313172.YM304_21730	1.215e-119	392.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CNK1@84992|Acidimicrobiia	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158347_k127_3685548_3	1313172.YM304_21720	2.436e-89	305.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CN2T@84992|Acidimicrobiia	84992|Acidimicrobiia	U	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158347_k127_3685548_4	1313172.YM304_21710	2.153e-86	299.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158347_k127_3685548_11	1313172.YM304_21700	1.22e-05	48.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158347_k127_3687195_5	1463909.KL585946_gene1519	1.326e-38	149.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158347_k127_3687195_1	1108045.GORHZ_134_00040	1.082e-93	319.0	2DM5A@1|root,31SBV@2|Bacteria,2IPT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3687195_6	28444.JODQ01000003_gene4846	6.928e-21	96.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4EKDK@85012|Streptosporangiales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158347_k127_3687195_0	1449976.KALB_4129	0.0	1082.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4DZ0E@85010|Pseudonocardiales	201174|Actinobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158347_k127_3687195_7	477641.MODMU_1119	6.769e-07	56.0	COG2329@1|root,COG2329@2|Bacteria,2IQBH@201174|Actinobacteria,4EWB0@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158347_k127_3687195_3	1463857.JOFZ01000009_gene6197	4.025e-60	215.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158347_k127_3687195_4	33898.JRHJ01000089_gene2619	1.493e-40	154.0	2BVXR@1|root,32QYG@2|Bacteria,2I832@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158347_k127_3687195_2	208444.JNYY01000001_gene5580	3.06e-71	254.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4DY40@85010|Pseudonocardiales	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158347_k127_3688122_7	1121413.JMKT01000009_gene2017	4.952e-56	209.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42ZNH@68525|delta/epsilon subdivisions,2WV22@28221|Deltaproteobacteria,2MG18@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_3688122_8	926549.KI421517_gene3913	1.338e-55	204.0	COG5012@1|root,COG5012@2|Bacteria,4NRCW@976|Bacteroidetes,47UR1@768503|Cytophagia	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158347_k127_3688122_22	1111069.TCCBUS3UF1_11930	0.0002173	53.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1WJKU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
SRR25158347_k127_3688122_14	566466.NOR53_767	2.379e-37	147.0	COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria	1224|Proteobacteria	K	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158347_k127_3688122_1	479434.Sthe_0131	9.063e-186	602.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi,27XU1@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158347_k127_3688122_18	1278078.G419_14749	5.066e-19	91.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria,4G28G@85025|Nocardiaceae	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158347_k127_3688122_13	1394178.AWOO02000002_gene1691	2.6e-40	168.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_3688122_3	1229780.BN381_450023	1.022e-68	237.0	COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,3UWN1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Domain of unknown function (DUF4916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4916
SRR25158347_k127_3688122_9	1380390.JIAT01000014_gene6273	3.953e-52	204.0	COG2267@1|root,COG2267@2|Bacteria,2HFRI@201174|Actinobacteria,4CQZ8@84995|Rubrobacteria	84995|Rubrobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,SCP2
SRR25158347_k127_3688122_17	479431.Namu_3292	1.18e-27	121.0	COG3467@1|root,COG3467@2|Bacteria,2GQIA@201174|Actinobacteria,4ETAQ@85013|Frankiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158347_k127_3688122_20	192952.MM_2606	3.003e-11	76.0	COG3177@1|root,arCOG03110@2157|Archaea,2XUN8@28890|Euryarchaeota	28890|Euryarchaeota	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_11,HTH_24,TrmB
SRR25158347_k127_3688122_2	1313172.YM304_33000	3.346e-84	290.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CN1K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158347_k127_3688122_15	1088721.NSU_0890	3.315e-30	127.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,2K5XU@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158347_k127_3688122_19	1384057.CD33_10935	2.454e-14	78.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,3IW81@400634|Lysinibacillus	91061|Bacilli	K	LuxR family transcriptional regulator	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158347_k127_3688122_12	1211815.CBYP010000036_gene2285	3.82e-41	160.0	COG2197@1|root,COG2197@2|Bacteria,2IG2I@201174|Actinobacteria,4EVZJ@85013|Frankiales	201174|Actinobacteria	T	Two component regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_3688122_6	500153.JOEK01000015_gene2750	9.588e-57	220.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria	201174|Actinobacteria	H	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158347_k127_3688122_5	1463856.JOHY01000033_gene2895	1.365e-57	214.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158347_k127_3688122_16	66875.JODY01000004_gene3354	7.508e-28	120.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria	201174|Actinobacteria	H	Molybdopterin	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158347_k127_3688122_4	1156844.KB891799_gene1235	2.31e-63	235.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,TIG
SRR25158347_k127_3688122_10	356851.JOAN01000017_gene5966	1.423e-50	194.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4D9ZI@85008|Micromonosporales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158347_k127_3688122_11	1131730.BAVI_02784	3.059e-43	183.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158347_k127_3688122_21	525909.Afer_1872	6.204e-09	68.0	COG2268@1|root,COG2268@2|Bacteria,2I6VU@201174|Actinobacteria,4CN97@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3688122_0	656024.FsymDg_0937	9.682e-204	671.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4ERVJ@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158347_k127_3711429_25	391603.FBALC1_09757	3.904e-07	61.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NGKK@976|Bacteroidetes,1HX0I@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_3711429_12	1229780.BN381_150050	2.006e-48	191.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
SRR25158347_k127_3711429_20	1068978.AMETH_6172	1.984e-26	111.0	COG0695@1|root,COG0695@2|Bacteria,2HNF0@201174|Actinobacteria,4E6IC@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM glutaredoxin	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
SRR25158347_k127_3711429_17	408672.NBCG_03921	4.542e-34	138.0	COG2259@1|root,COG2259@2|Bacteria,2IJ0I@201174|Actinobacteria,4DRJ9@85009|Propionibacteriales	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158347_k127_3711429_13	196162.Noca_2335	5.361e-41	154.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4DSSJ@85009|Propionibacteriales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158347_k127_3711429_15	479431.Namu_3223	3.524e-37	147.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158347_k127_3711429_0	1068978.AMETH_4233	7.596e-200	627.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4DZ4D@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158347_k127_3711429_16	1123024.AUII01000016_gene1273	1.002e-35	139.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4E613@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
SRR25158347_k127_3711429_1	1122939.ATUD01000004_gene3874	2.999e-170	550.0	COG0488@1|root,COG0488@2|Bacteria,2GMUD@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158347_k127_3711429_23	2002.JOEQ01000033_gene1720	2.089e-11	68.0	2EBG9@1|root,335GU@2|Bacteria,2IJZI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
SRR25158347_k127_3711429_18	591157.SSLG_01305	1.738e-33	137.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria	201174|Actinobacteria	P	reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158347_k127_3711429_9	1219035.NT2_07_01040	2.715e-76	265.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_3711429_21	1123320.KB889669_gene3270	1.147e-19	90.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	fdxD	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SRR25158347_k127_3711429_6	326424.FRAAL4010	1.527e-96	330.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158347_k127_3711429_3	391625.PPSIR1_33746	1.183e-124	414.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,42NJV@68525|delta/epsilon subdivisions,2WJBT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158347_k127_3711429_2	287986.DV20_43340	2.004e-163	528.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4DZY2@85010|Pseudonocardiales	201174|Actinobacteria	E	glutamate decarboxylase	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158347_k127_3711429_4	1415780.JPOG01000001_gene674	5.997e-120	405.0	28JDP@1|root,2Z97Z@2|Bacteria,1R6U7@1224|Proteobacteria,1S0CD@1236|Gammaproteobacteria,1XBI8@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3711429_7	253839.SSNG_00329	5.233e-92	309.0	COG0412@1|root,COG0412@2|Bacteria,2GK7H@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158347_k127_3711429_5	1229780.BN381_150112	5.861e-109	373.0	COG1283@1|root,COG1283@2|Bacteria,2IAMX@201174|Actinobacteria	201174|Actinobacteria	P	Na+/Pi-cotransporter	nptA	-	-	ko:K03324,ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1,2.A.58.2	-	-	Na_Pi_cotrans
SRR25158347_k127_3711429_14	1229780.BN381_150111	6.248e-40	156.0	COG0704@1|root,COG0704@2|Bacteria,2H63V@201174|Actinobacteria	201174|Actinobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
SRR25158347_k127_3711429_11	40571.JOEA01000037_gene6799	4.695e-62	228.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
SRR25158347_k127_3711429_8	1146883.BLASA_4847	3.638e-78	286.0	COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria,4ERJX@85013|Frankiales	201174|Actinobacteria	O	PFAM glycosyl transferase family 39	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
SRR25158347_k127_3711429_10	665577.JH993790_gene2724	3.386e-68	257.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158347_k127_3711429_22	1356854.N007_00240	1.579e-14	78.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,278GZ@186823|Alicyclobacillaceae	91061|Bacilli	K	Antidote-toxin recognition MazE, bacterial antitoxin	abrB	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
SRR25158347_k127_3711429_19	1054860.KB913030_gene3164	1.837e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigE	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3714480_0	479434.Sthe_2247	1.086e-186	623.0	COG2909@1|root,COG2909@2|Bacteria,2G80F@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158347_k127_3714480_6	526225.Gobs_0857	1.293e-44	185.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2I39H@201174|Actinobacteria,4EXCD@85013|Frankiales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TIR_2,TPR_10,TPR_12
SRR25158347_k127_3714480_2	1279009.ADICEAN_02905	6.544e-76	281.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_2,TPR_8
SRR25158347_k127_3714480_1	1279009.ADICEAN_02904	1.839e-116	390.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,47M51@768503|Cytophagia	976|Bacteroidetes	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
SRR25158347_k127_3714480_5	66429.JOFL01000001_gene4495	5.514e-50	188.0	COG3629@1|root,COG3629@2|Bacteria,2IC17@201174|Actinobacteria	201174|Actinobacteria	T	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158347_k127_3714480_10	1283299.AUKG01000001_gene2158	4.609e-08	59.0	2B8TX@1|root,32240@2|Bacteria,2HRST@201174|Actinobacteria,4CTW1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3714480_4	977880.RALTA_A1751	8.283e-61	225.0	COG5649@1|root,COG5649@2|Bacteria,1RDDG@1224|Proteobacteria,2W0C7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158347_k127_3714480_3	1078020.KEK_16333	6.02e-66	234.0	COG3832@1|root,COG3832@2|Bacteria,2IH2T@201174|Actinobacteria,238V6@1762|Mycobacteriaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158347_k127_3714480_7	1194972.MVAC_10362	9.785e-39	146.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,239X1@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158347_k127_3722471_6	2002.JOEQ01000045_gene861	3.632e-61	221.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4EIHA@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158347_k127_3722471_2	1121423.JONT01000029_gene2386	2.684e-121	409.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2609V@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158347_k127_3722471_17	589865.DaAHT2_0768	1.334e-10	74.0	COG4655@1|root,COG4655@2|Bacteria,1R41B@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
SRR25158347_k127_3722471_15	272560.BPSL1897	1.052e-16	87.0	COG4961@1|root,COG4961@2|Bacteria,1NAK6@1224|Proteobacteria,2VX8Z@28216|Betaproteobacteria,1K8U3@119060|Burkholderiaceae	28216|Betaproteobacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158347_k127_3722471_9	935866.JAER01000009_gene769	9.261e-51	193.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4DR34@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158347_k127_3722471_8	397278.JOJN01000004_gene1179	2.159e-52	198.0	COG2304@1|root,COG4965@1|root,COG2304@2|Bacteria,COG4965@2|Bacteria,2H577@201174|Actinobacteria,4DQ0A@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF,VWA_2
SRR25158347_k127_3722471_0	685727.REQ_18410	1.01e-148	484.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4FUYS@85025|Nocardiaceae	201174|Actinobacteria	U	Type II/IV secretion system protein	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158347_k127_3722471_13	1385519.N801_10850	1.32e-38	165.0	COG4963@1|root,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,4FG1C@85021|Intrasporangiaceae	201174|Actinobacteria	D	chromosome partitioning	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
SRR25158347_k127_3722471_10	1229780.BN381_430006	1.537e-50	188.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,3UWZH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158347_k127_3722471_16	1128421.JAGA01000002_gene1100	6.753e-16	92.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158347_k127_3722471_12	1122951.ATUE01000007_gene578	1.399e-42	171.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,3NKQT@468|Moraxellaceae	1236|Gammaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3360	YgbB
SRR25158347_k127_3722471_14	446466.Cfla_0664	8.297e-37	148.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4F191@85016|Cellulomonadaceae	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158347_k127_3722471_5	351607.Acel_0079	1.08e-68	246.0	COG4956@1|root,COG4956@2|Bacteria	2|Bacteria	S	nuclease activity	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
SRR25158347_k127_3722471_11	1035191.HMPREF0185_02688	3.681e-46	174.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2KGHH@204458|Caulobacterales	204458|Caulobacterales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158347_k127_3722471_1	1246995.AFR_08120	9.242e-134	437.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DABI@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158347_k127_3722471_7	1123024.AUII01000002_gene1190	4.125e-53	192.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4DXYN@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158347_k127_3722471_3	351607.Acel_0229	6.15e-121	398.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4ERXA@85013|Frankiales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158347_k127_3722471_4	101510.RHA1_ro01676	1.656e-87	305.0	COG0568@1|root,COG1061@1|root,COG0568@2|Bacteria,COG1061@2|Bacteria,2I8PT@201174|Actinobacteria,4FUJ6@85025|Nocardiaceae	201174|Actinobacteria	L	ERCC3/RAD25/XPB C-terminal helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
SRR25158347_k127_3730141_10	675635.Psed_5109	1.736e-05	49.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2GKCY@201174|Actinobacteria,4EB4D@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
SRR25158347_k127_3730141_7	1463853.JOHW01000005_gene4018	3.542e-32	144.0	COG2912@1|root,COG2912@2|Bacteria,2GMER@201174|Actinobacteria	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158347_k127_3730141_8	994479.GL877881_gene6296	5.259e-23	114.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4E1AW@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_3730141_0	471857.Svir_31520	3.958e-122	402.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4DYE8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158347_k127_3730141_1	1210045.ALNP01000001_gene3246	1.481e-110	364.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158347_k127_3730141_4	1313172.YM304_07690	6.987e-78	276.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158347_k127_3730141_2	1313172.YM304_07700	2.451e-82	283.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158347_k127_3730141_5	102232.GLO73106DRAFT_00023150	6.283e-74	265.0	COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158347_k127_3730141_9	1206735.BAGG01000266_gene7031	5.319e-23	109.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4FY1I@85025|Nocardiaceae	201174|Actinobacteria	P	PhoU domain	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158347_k127_3730141_3	1150399.AQYK01000002_gene2827	8.414e-80	279.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4FKR2@85023|Microbacteriaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_3730141_6	1232443.BAIA02000125_gene1201	8.124e-53	204.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,267JS@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
SRR25158347_k127_3736012_6	1283283.ATXA01000002_gene2659	5.948e-58	208.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4ES3J@85013|Frankiales	201174|Actinobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_3736012_8	1196322.A370_03674	4.085e-15	85.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_3736012_4	1268072.PSAB_22225	6.378e-94	318.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,26S8W@186822|Paenibacillaceae	91061|Bacilli	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158347_k127_3736012_7	446470.Snas_3067	9.38e-29	123.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4EYM1@85014|Glycomycetales	201174|Actinobacteria	K	Arginine repressor, DNA binding domain	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158347_k127_3736012_2	649764.HMPREF0762_01301	1.322e-136	453.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CV0T@84998|Coriobacteriia	84998|Coriobacteriia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158347_k127_3736012_1	1122611.KB904007_gene7735	1.225e-145	476.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4EGRC@85012|Streptosporangiales	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158347_k127_3736012_0	502025.Hoch_6605	1.818e-184	594.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YX9H@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158347_k127_3736012_5	1120950.KB892768_gene5195	4.28e-61	219.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DQWP@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	alkA	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158347_k127_3736012_3	1229780.BN381_290106	3.376e-115	397.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,3UW69@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158347_k127_3736261_13	935836.JAEL01000005_gene2755	4.303e-14	83.0	COG2247@1|root,COG2385@1|root,COG2247@2|Bacteria,COG2385@2|Bacteria,1V9XE@1239|Firmicutes,4HDNT@91061|Bacilli,1ZF67@1386|Bacillus	91061|Bacilli	D	Stage II sporulation protein	lytB	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	CW_binding_2,PG_binding_1,SH3_3,SpoIID
SRR25158347_k127_3736261_14	710696.Intca_3462	2.255e-09	68.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158347_k127_3736261_12	1380390.JIAT01000009_gene2197	1.601e-18	93.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158347_k127_3736261_11	1229780.BN381_130137	2.838e-55	206.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_3736261_9	649638.Trad_1694	2.177e-56	210.0	COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_3736261_4	479434.Sthe_3287	7.989e-118	392.0	COG3642@1|root,COG3642@2|Bacteria,2G920@200795|Chloroflexi	200795|Chloroflexi	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
SRR25158347_k127_3736261_3	408672.NBCG_01460	9.237e-121	406.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4DPNK@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158347_k127_3736261_6	408672.NBCG_01461	1.059e-103	347.0	COG1175@1|root,COG1175@2|Bacteria,2GKYS@201174|Actinobacteria,4DP26@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158347_k127_3736261_7	195250.CM001776_gene383	4.211e-91	316.0	COG1653@1|root,COG1653@2|Bacteria,1G3MQ@1117|Cyanobacteria,1GZIG@1129|Synechococcus	1117|Cyanobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158347_k127_3736261_2	1394178.AWOO02000044_gene4495	8.262e-140	454.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EMXE@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158347_k127_3736261_1	446470.Snas_3307	1.44e-154	506.0	COG0366@1|root,COG0637@1|root,COG0366@2|Bacteria,COG0637@2|Bacteria,2GKS4@201174|Actinobacteria	201174|Actinobacteria	G	alpha amylase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158347_k127_3736261_10	471853.Bcav_1099	2.294e-56	211.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria	201174|Actinobacteria	G	PfkB family	cscK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158347_k127_3736261_0	1146883.BLASA_3982	0.0	1336.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4ES2Q@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158347_k127_3736261_8	1242864.D187_003477	7.441e-66	258.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein 2	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158347_k127_3736261_5	298653.Franean1_6600	3.476e-115	420.0	COG2319@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3629@2|Bacteria,2GJN3@201174|Actinobacteria,4ES8H@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,PD40,Trans_reg_C,WD40
SRR25158347_k127_3743910_4	1068980.ARVW01000001_gene2303	4.971e-125	408.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DX8B@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_3743910_3	405948.SACE_6564	5.364e-131	428.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DYMF@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158347_k127_3743910_1	882082.SaccyDRAFT_1619	9.512e-195	617.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DXGM@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158347_k127_3743910_0	861299.J421_3601	4.383e-204	645.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158347_k127_3743910_6	1173025.GEI7407_0742	4.031e-111	382.0	COG3975@1|root,COG3975@2|Bacteria,1G0YP@1117|Cyanobacteria,1H7J1@1150|Oscillatoriales	1117|Cyanobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158347_k127_3743910_9	1380370.JIBA01000014_gene2150	5.681e-35	142.0	COG2259@1|root,COG2259@2|Bacteria,2HD6Y@201174|Actinobacteria,4FGKG@85021|Intrasporangiaceae	201174|Actinobacteria	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158347_k127_3743910_8	1229780.BN381_410037	4.654e-36	141.0	2DMMI@1|root,32SFN@2|Bacteria,2IKP6@201174|Actinobacteria,3UXKS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
SRR25158347_k127_3743910_2	1120950.KB892823_gene556	5.806e-145	482.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4DP3K@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158347_k127_3743910_5	1463845.JOIG01000001_gene1728	1.129e-111	383.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158347_k127_3743910_7	909613.UO65_2920	1.733e-64	237.0	COG0477@1|root,COG0477@2|Bacteria,2I2J7@201174|Actinobacteria,4E1M7@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158347_k127_40857_2	1169152.AXVD01000007_gene1893	3.833e-37	153.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Asp_protease_2,Chlorophyllase2,DLH
SRR25158347_k127_40857_4	1123024.AUII01000036_gene3160	2.57e-14	79.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_40857_1	1123024.AUII01000036_gene3161	2.346e-38	147.0	2E73E@1|root,33X4K@2|Bacteria,2GV9A@201174|Actinobacteria,4E7YP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_40857_0	1242864.D187_001830	9.385e-155	530.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
SRR25158347_k127_40857_3	1395571.TMS3_0100965	6.074e-27	112.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158347_k127_431072_8	479434.Sthe_1981	7.422e-38	153.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
SRR25158347_k127_431072_4	1298863.AUEP01000006_gene3414	1.714e-63	231.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4DRSP@85009|Propionibacteriales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_431072_0	1207063.P24_06132	1.558e-231	742.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158347_k127_431072_1	1236902.ANAS01000022_gene187	5.994e-164	529.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4EH4Z@85012|Streptosporangiales	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158347_k127_431072_5	867903.ThesuDRAFT_00213	4.303e-47	188.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WCHZ@538999|Clostridiales incertae sedis	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158347_k127_431072_10	525909.Afer_0488	7.69e-22	100.0	COG2331@1|root,COG2331@2|Bacteria,2HGEB@201174|Actinobacteria,4CP29@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_431072_9	1540257.JQMW01000013_gene1032	2.558e-24	111.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,36JPF@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158347_k127_431072_2	1306990.BARG01000046_gene5525	3.393e-106	352.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria	201174|Actinobacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158347_k127_431072_3	351607.Acel_0167	1.538e-102	347.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4ERWC@85013|Frankiales	201174|Actinobacteria	H	MoeA domain protein domain I and II	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158347_k127_431072_6	1283299.AUKG01000001_gene1878	2.43e-44	166.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CSG6@84995|Rubrobacteria	84995|Rubrobacteria	H	MoaC family	-	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158347_k127_431072_7	479434.Sthe_0893	1.046e-43	167.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,27Y62@189775|Thermomicrobia	189775|Thermomicrobia	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
SRR25158347_k127_431072_12	1540221.JQNI01000002_gene2188	0.0007774	52.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158347_k127_431072_11	110319.CF8_2343	1.606e-05	56.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DPHY@85009|Propionibacteriales	201174|Actinobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158347_k127_442512_25	1429046.RR21198_1105	3.495e-46	167.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4FUI6@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_442512_13	43354.JOIJ01000014_gene865	1.014e-86	299.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4E1AW@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_442512_14	1380390.JIAT01000009_gene335	1.653e-85	296.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4CSKB@84995|Rubrobacteria	84995|Rubrobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158347_k127_442512_24	1304865.JAGF01000001_gene983	1.862e-47	179.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria	201174|Actinobacteria	J	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158347_k127_442512_32	1380354.JIAN01000005_gene1753	2.506e-07	61.0	2CPKI@1|root,32SJC@2|Bacteria,2IQPS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
SRR25158347_k127_442512_28	2045.KR76_08800	9.147e-19	94.0	2B1ET@1|root,31TVH@2|Bacteria,2GT2S@201174|Actinobacteria,4DSY2@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_442512_31	40571.JOEA01000014_gene1907	1.467e-10	74.0	2BMGV@1|root,32G1K@2|Bacteria,2IP6V@201174|Actinobacteria,4E9PP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_442512_15	2045.KR76_08790	1.013e-84	296.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria,4DTWF@85009|Propionibacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158347_k127_442512_11	196162.Noca_4016	1.563e-88	300.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPPJ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_442512_3	1121272.KB903292_gene3947	9.31e-142	474.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4DJIF@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_442512_19	479433.Caci_8308	2.181e-72	263.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_442512_7	67275.JOAP01000054_gene159	4.991e-104	347.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158347_k127_442512_18	710687.KI912270_gene2194	6.292e-74	274.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,236CQ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158347_k127_442512_2	1121272.KB903292_gene3988	2.109e-142	462.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,4DBEX@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE26	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_442512_27	479433.Caci_5897	1.949e-31	132.0	COG2050@1|root,COG2050@2|Bacteria,2GK27@201174|Actinobacteria	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_442512_20	247639.MGP2080_10438	1.578e-63	227.0	COG4221@1|root,COG4221@2|Bacteria,1MV0A@1224|Proteobacteria,1S2V4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_442512_29	525368.HMPREF0591_5425	3.438e-15	78.0	COG1141@1|root,COG1141@2|Bacteria,2GSJR@201174|Actinobacteria,23BHW@1762|Mycobacteriaceae	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	fdxD_1	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
SRR25158347_k127_442512_8	1229780.BN381_250088	1.085e-103	354.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158347_k127_442512_9	1068978.AMETH_4853	9.304e-95	325.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4DZK5@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158347_k127_442512_6	981369.JQMJ01000004_gene6287	2.13e-121	396.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria,2NGVI@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_442512_5	1463820.JOGW01000012_gene3895	2.12e-125	407.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_442512_26	1211815.CBYP010000006_gene276	3.02e-35	147.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_442512_12	1121937.AUHJ01000011_gene2849	1.626e-88	308.0	COG2124@1|root,COG2124@2|Bacteria,1N0ID@1224|Proteobacteria,1SZ19@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome P450	-	-	1.14.15.13	ko:K17474	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158347_k127_442512_22	1229780.BN381_80395	1.647e-62	225.0	COG1024@1|root,COG1024@2|Bacteria,2IAFJ@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_442512_1	479433.Caci_8740	9.457e-177	569.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_442512_17	1521187.JPIM01000002_gene3156	4.549e-74	263.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_442512_10	685727.REQ_04810	2.967e-94	321.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4FU8Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_442512_21	298655.KI912266_gene3621	4.818e-63	234.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria,4EV6X@85013|Frankiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_442512_16	1123320.KB889585_gene1873	2.6e-74	276.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158347_k127_442512_0	1123320.KB889585_gene1872	9.705e-187	590.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_442512_30	318586.Pden_0676	2.739e-14	81.0	COG0730@1|root,COG0730@2|Bacteria,1R7YW@1224|Proteobacteria,2VEXS@28211|Alphaproteobacteria,2PV43@265|Paracoccus	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158347_k127_442512_23	1123320.KB889685_gene2189	6.991e-59	213.0	28K5H@1|root,2Z9U4@2|Bacteria,2GKEQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_442512_4	298655.KI912266_gene6070	1.703e-136	440.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EU6F@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_456654_5	1033730.CAHG01000008_gene3029	8.75e-77	274.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4DPJQ@85009|Propionibacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158347_k127_456654_7	1007103.AFHW01000107_gene5191	7.338e-31	136.0	COG0640@1|root,COG0640@2|Bacteria,1TSRQ@1239|Firmicutes,4HBXM@91061|Bacilli,26STR@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158347_k127_456654_1	1146883.BLASA_4985	1.501e-114	404.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
SRR25158347_k127_456654_9	237368.SCABRO_03564	1.933e-25	124.0	COG3291@1|root,COG3291@2|Bacteria,2J1GZ@203682|Planctomycetes	203682|Planctomycetes	U	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158347_k127_456654_4	1449044.JMLE01000002_gene4365	6.083e-79	278.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,1WANZ@1268|Micrococcaceae	201174|Actinobacteria	U	Secretion system protein	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158347_k127_456654_15	1463841.JOIR01000007_gene3784	1.897e-09	70.0	COG2064@1|root,COG2064@2|Bacteria,2IQE9@201174|Actinobacteria	201174|Actinobacteria	NU	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158347_k127_456654_8	1313172.YM304_09590	2.869e-28	126.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CNXW@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158347_k127_456654_13	1219084.AP014508_gene1257	3.258e-13	82.0	COG0683@1|root,COG0683@2|Bacteria,2GCEV@200918|Thermotogae	2|Bacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158347_k127_456654_16	1297863.APJF01000009_gene220	1.172e-07	63.0	COG0559@1|root,COG0559@2|Bacteria,1R5KF@1224|Proteobacteria,2U3IU@28211|Alphaproteobacteria,3JXYI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_456654_12	426716.JOAJ01000001_gene1045	4.382e-14	87.0	COG4559@1|root,COG4559@2|Bacteria,2GMUI@201174|Actinobacteria,4FVC2@85025|Nocardiaceae	201174|Actinobacteria	P	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system	hmuV	-	1.14.15.20,3.6.3.34	ko:K02013,ko:K21480	ko00860,ko01100,ko01110,ko02010,map00860,map01100,map01110,map02010	M00240	R11579	RC01270	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158347_k127_456654_17	1306990.BARG01000052_gene6180	3.833e-07	64.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_456654_18	1396141.BATP01000016_gene2792	0.0005903	52.0	COG1404@1|root,COG3540@1|root,COG1404@2|Bacteria,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PhoD
SRR25158347_k127_456654_0	298655.KI912266_gene1500	1.386e-247	786.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4ERHU@85013|Frankiales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158347_k127_456654_10	1172188.KB911824_gene3184	6.712e-25	119.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4FEU8@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158347_k127_456654_14	1182590.BN5_04099	2.712e-11	73.0	COG0500@1|root,COG2226@2|Bacteria,1QU8Z@1224|Proteobacteria,1RS1E@1236|Gammaproteobacteria,1YM04@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158347_k127_456654_11	1464048.JNZS01000006_gene4084	3.738e-15	83.0	2DIQ5@1|root,32UBF@2|Bacteria,2IMKR@201174|Actinobacteria,4DE92@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_456654_3	351607.Acel_1595	1.016e-81	282.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4ERZW@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, winged helix family	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_456654_2	469383.Cwoe_1565	8.934e-84	297.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_456654_6	1123319.AUBE01000004_gene460	1.118e-48	189.0	COG3173@1|root,COG3173@2|Bacteria,2I4D0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_492341_4	287986.DV20_40985	4.624e-26	114.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,2GK1J@201174|Actinobacteria,4DZ3R@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_492341_0	1246995.AFR_10105	1.352e-116	392.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4DA72@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
SRR25158347_k127_492341_1	711393.AYRX01000022_gene1237	1.581e-82	289.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_492341_2	351607.Acel_1060	1.015e-68	243.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4ESDH@85013|Frankiales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158347_k127_492341_3	106370.Francci3_3024	2.141e-49	187.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4ES6K@85013|Frankiales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158347_k127_493690_15	1161401.ASJA01000001_gene532	6.428e-43	160.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,43XHY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158347_k127_493690_13	1463856.JOHY01000065_gene5471	1.392e-47	188.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158347_k127_493690_17	870187.Thini_3998	1.564e-33	148.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,462RW@72273|Thiotrichales	72273|Thiotrichales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	-	-	-	-	-	-	-	-	-	-	HPPK
SRR25158347_k127_493690_18	928724.SacglDRAFT_03952	2.185e-33	145.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,4E4Z9@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158347_k127_493690_4	1207063.P24_18451	6.153e-70	251.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,2JP97@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158347_k127_493690_6	298654.FraEuI1c_0305	2.247e-67	253.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4ERHB@85013|Frankiales	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158347_k127_493690_0	710111.FraQA3DRAFT_5133	6.29e-236	748.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4ERQQ@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158347_k127_493690_9	555079.Toce_2097	8.174e-62	227.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,42G9G@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158347_k127_493690_14	1297742.A176_00169	7.475e-44	177.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158347_k127_493690_12	1944.JOAZ01000022_gene3177	2.191e-48	186.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4186J@629295|Streptomyces griseus group	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158347_k127_493690_19	1122622.ATWJ01000008_gene2981	6.301e-31	139.0	COG2385@1|root,COG2931@1|root,COG2385@2|Bacteria,COG2931@2|Bacteria,2GKS7@201174|Actinobacteria,4FFUE@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91
SRR25158347_k127_493690_25	929558.SMGD1_1762	1.934e-07	62.0	COG2199@1|root,COG2703@1|root,COG2703@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42UYY@68525|delta/epsilon subdivisions	1224|Proteobacteria	PT	Diguanylate cyclase, possibly nitrate nitrite or cation sensing (GGDEF HAMP linker domain, Hemerythrin HHE domain)	-	-	2.7.7.65	ko:K21088	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Hemerythrin,NIT,PilJ,dCache_3
SRR25158347_k127_493690_22	1380390.JIAT01000009_gene673	1.619e-20	99.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	yeaK	GO:0002161,GO:0002196,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006417,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0045727,GO:0045903,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:2000112	6.1.1.23	ko:K09759,ko:K19055	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HDOD,tRNA_edit
SRR25158347_k127_493690_3	1242864.D187_004691	2.567e-73	265.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria	1224|Proteobacteria	Q	Acyltransferase, ws dgat mgat	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158347_k127_493690_20	247634.GPB2148_1540	4.541e-29	121.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158347_k127_493690_24	1121938.AUDY01000008_gene1094	6.519e-08	66.0	COG2247@1|root,COG2247@2|Bacteria,1VR7P@1239|Firmicutes,4HUJE@91061|Bacilli	91061|Bacilli	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
SRR25158347_k127_493690_26	1120958.AULD01000005_gene1833	4.54e-07	63.0	COG2385@1|root,COG5479@1|root,COG2385@2|Bacteria,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria,4FN2P@85023|Microbacteriaceae	201174|Actinobacteria	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LGFP
SRR25158347_k127_493690_23	1449126.JQKL01000011_gene3603	6.566e-15	89.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_493690_1	1304275.C41B8_04296	3.279e-112	375.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	abc transporter atp-binding protein	yehX	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158347_k127_493690_8	208444.JNYY01000028_gene2524	8.26e-63	223.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,4DYJM@85010|Pseudonocardiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158347_k127_493690_10	1068980.ARVW01000001_gene2722	1.646e-55	203.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria,4E1XU@85010|Pseudonocardiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158347_k127_493690_5	591158.SSMG_00178	2.601e-68	244.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria	201174|Actinobacteria	M	Glycine betaine	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158347_k127_493690_11	869210.Marky_0686	3.635e-52	205.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158347_k127_493690_7	164757.Mjls_3659	1.083e-66	239.0	COG2116@1|root,COG2116@2|Bacteria,2GNU6@201174|Actinobacteria,234AS@1762|Mycobacteriaceae	201174|Actinobacteria	P	Formate nitrite	focA	-	-	-	-	-	-	-	-	-	-	-	Form_Nir_trans
SRR25158347_k127_493690_16	448385.sce8824	4.953e-35	140.0	COG1832@1|root,COG1832@2|Bacteria,1NJW8@1224|Proteobacteria,42WY1@68525|delta/epsilon subdivisions,2WT3S@28221|Deltaproteobacteria,2Z10K@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
SRR25158347_k127_493690_2	1042377.AFPJ01000008_gene1990	1.728e-91	317.0	COG0477@1|root,COG2814@2|Bacteria,1PR3J@1224|Proteobacteria,1RPWR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158347_k127_493690_21	378806.STAUR_3434	3.4e-28	116.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,42XM7@68525|delta/epsilon subdivisions,2WSTY@28221|Deltaproteobacteria,2YWYZ@29|Myxococcales	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158347_k127_49882_20	324057.Pjdr2_2798	1.537e-09	63.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,26T6H@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type phosphate phosphonate transport system, permease component	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
SRR25158347_k127_49882_6	1043493.BBLU01000002_gene1727	1.403e-112	372.0	COG3638@1|root,COG3638@2|Bacteria,2GK02@201174|Actinobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
SRR25158347_k127_49882_12	1313172.YM304_34880	2.755e-54	204.0	COG3221@1|root,COG3221@2|Bacteria,2I7EX@201174|Actinobacteria	201174|Actinobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158347_k127_49882_9	1313172.YM304_34870	1.277e-69	248.0	COG5663@1|root,COG5663@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
SRR25158347_k127_49882_18	1122917.KB899660_gene1653	2.731e-15	86.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,4HA6N@91061|Bacilli,26T8F@186822|Paenibacillaceae	91061|Bacilli	J	Pseudouridine synthase	rluC	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SRR25158347_k127_49882_8	1206730.BAGA01000183_gene3183	2.14e-72	248.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4FVU7@85025|Nocardiaceae	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	gca	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158347_k127_49882_19	1123258.AQXZ01000019_gene2777	2.646e-12	78.0	COG2852@1|root,COG2852@2|Bacteria,2GKCY@201174|Actinobacteria,4G0JY@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
SRR25158347_k127_49882_4	208439.AJAP_00365	2.045e-136	438.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4E05D@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	mcl2	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI,PEP-utilizers_C
SRR25158347_k127_49882_2	1449976.KALB_2473	8.559e-183	576.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4E0H5@85010|Pseudonocardiales	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158347_k127_49882_10	1445613.JALM01000062_gene3426	5.543e-67	241.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4DZ99@85010|Pseudonocardiales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_49882_13	479435.Kfla_0952	2.016e-52	198.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria,4DMZ0@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC1	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158347_k127_49882_14	1223544.GSI01S_20_00860	5.173e-48	183.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria,4GC5K@85026|Gordoniaceae	201174|Actinobacteria	I	Phosphate acyltransferases	plsC1	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158347_k127_49882_5	562970.Btus_1044	3.069e-126	414.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,278CR@186823|Alicyclobacillaceae	91061|Bacilli	E	Aminotransferase class-V	pucG	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R10908	RC00006,RC00008,RC00018,RC03305	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158347_k127_49882_16	543632.JOJL01000038_gene3079	1.862e-26	123.0	COG4191@1|root,COG4191@2|Bacteria,2GSHF@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158347_k127_49882_15	208439.AJAP_28455	3.089e-36	155.0	COG0642@1|root,COG2197@1|root,COG3447@1|root,COG4251@1|root,COG2197@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,COG4251@2|Bacteria,2GJB0@201174|Actinobacteria,4E2NH@85010|Pseudonocardiales	201174|Actinobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	MASE1
SRR25158347_k127_49882_11	1304865.JAGF01000001_gene2779	3.946e-60	214.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4F14N@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM Acetolactate synthase, small subunit-like	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158347_k127_49882_0	1385518.N798_17255	1.054e-219	699.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4FFIE@85021|Intrasporangiaceae	201174|Actinobacteria	E	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158347_k127_49882_17	477641.MODMU_2307	6.534e-20	100.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF3703,PAP2
SRR25158347_k127_49882_1	1116232.AHBF01000118_gene4341	1.287e-195	628.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria	201174|Actinobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158347_k127_49882_3	471852.Tcur_3558	2.346e-147	491.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4EHUN@85012|Streptosporangiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158347_k127_49882_7	111780.Sta7437_3655	6.203e-109	361.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,3VNJR@52604|Pleurocapsales	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158347_k127_503015_2	1123320.KB889733_gene6269	1.828e-40	155.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furA	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158347_k127_503015_0	626887.J057_15880	0.0	1056.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4641A@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158347_k127_503015_1	1435356.Y013_05145	5.149e-119	398.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4FWK9@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158347_k127_503015_3	44060.JODL01000002_gene2155	1.303e-15	86.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158347_k127_503015_4	273677.BW34_01585	2.047e-07	62.0	2EGCD@1|root,33A46@2|Bacteria,2HST0@201174|Actinobacteria,4FQBR@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Septum_form
SRR25158347_k127_503015_5	1123319.AUBE01000012_gene6207	2.691e-06	59.0	COG0484@1|root,COG0484@2|Bacteria,2GRB9@201174|Actinobacteria	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158347_k127_53752_5	1323361.JPOC01000029_gene2391	0.0001903	52.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158347_k127_53752_4	585531.HMPREF0063_10376	8.895e-16	83.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4DRPR@85009|Propionibacteriales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158347_k127_53752_1	1121933.AUHH01000007_gene3295	3.952e-35	138.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4DQ95@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158347_k127_53752_3	525909.Afer_0043	1.87e-17	90.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CN8W@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158347_k127_53752_2	44060.JODL01000037_gene3406	2.163e-33	138.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158347_k127_53752_0	570268.ANBB01000059_gene4202	9.261e-204	657.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,4EH2H@85012|Streptosporangiales	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158347_k127_560120_5	1463909.KL585946_gene1519	4.449e-65	226.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158347_k127_560120_8	196162.Noca_0214	9.563e-40	156.0	2EBYX@1|root,335Y6@2|Bacteria,2GU99@201174|Actinobacteria,4DW8H@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_560120_2	1292020.H483_0111815	6.556e-140	452.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_560120_1	1206732.BAGD01000054_gene2007	2.976e-166	539.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4FU1D@85025|Nocardiaceae	201174|Actinobacteria	M	ABC transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158347_k127_560120_3	58123.JOFJ01000014_gene5095	3.459e-105	354.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4EHEG@85012|Streptosporangiales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	galE4	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158347_k127_560120_0	1229780.BN381_90023	0.0	1077.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,3UX1U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
SRR25158347_k127_560120_6	47839.CCAU010000004_gene947	3.057e-54	205.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,234Y8@1762|Mycobacteriaceae	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158347_k127_560120_10	561175.KB894102_gene1093	2.687e-21	108.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4EFVH@85012|Streptosporangiales	201174|Actinobacteria	T	Domain of unknown function (DUF4118)	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR25158347_k127_560120_9	1323361.JPOC01000008_gene3428	2.527e-32	136.0	COG3170@1|root,COG3170@2|Bacteria,2ICMF@201174|Actinobacteria,4G99M@85025|Nocardiaceae	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_560120_4	1463855.JOHV01000001_gene1553	9.596e-68	243.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K16907	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_560120_7	1521187.JPIM01000018_gene455	6.807e-51	204.0	COG1668@1|root,COG1668@2|Bacteria,2G7R2@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158347_k127_560120_11	867845.KI911784_gene3387	2.574e-17	96.0	COG0842@1|root,COG0842@2|Bacteria,2G7IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158347_k127_563611_3	478749.BRYFOR_05099	3.539e-15	82.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
SRR25158347_k127_563611_0	518766.Rmar_0689	1.475e-223	726.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
SRR25158347_k127_563611_1	926569.ANT_08180	2.164e-74	261.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158347_k127_563611_4	1144307.PMI04_03241	6.038e-07	58.0	COG2186@1|root,COG2186@2|Bacteria,1RDAP@1224|Proteobacteria,2U7J4@28211|Alphaproteobacteria,2K27S@204457|Sphingomonadales	204457|Sphingomonadales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158347_k127_563611_2	1123320.KB889708_gene8186	6.192e-16	84.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	IV02_29395	-	-	ko:K03710,ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158347_k127_565694_7	326427.Cagg_3487	8.053e-78	280.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,376UU@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_565694_5	1123503.KB908057_gene2501	3.786e-93	318.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,2KFT1@204458|Caulobacterales	204458|Caulobacterales	E	Belongs to the peptidase M20A family. ArgE subfamily	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158347_k127_565694_6	469383.Cwoe_1068	9.518e-85	288.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CSRX@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158347_k127_565694_12	1029824.AFID01000002_gene1429	5.648e-44	175.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,1W9DB@1268|Micrococcaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158347_k127_565694_11	1048339.KB913029_gene3800	1.556e-62	230.0	COG1225@1|root,COG1225@2|Bacteria,2II4M@201174|Actinobacteria	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158347_k127_565694_15	1354300.AUQY01000005_gene91	5.677e-29	131.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,22H08@1570339|Peptoniphilaceae	186801|Clostridia	M	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158347_k127_565694_10	1282876.BAOK01000001_gene2147	4.145e-67	244.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,4BQ04@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158347_k127_565694_1	653386.HMPREF0975_02864	2.861e-180	573.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4D35U@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158347_k127_565694_18	28042.GU90_04220	2.938e-11	72.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4E5EA@85010|Pseudonocardiales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158347_k127_565694_2	1123320.KB889733_gene6264	1.499e-129	428.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158347_k127_565694_17	1408422.JHYF01000012_gene3169	9.503e-14	79.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,36IRT@31979|Clostridiaceae	186801|Clostridia	J	RNA binding S1 domain protein	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
SRR25158347_k127_565694_13	1123320.KB889574_gene5705	7.588e-41	158.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria	201174|Actinobacteria	S	Septum formation initiator family protein	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158347_k127_565694_8	675635.Psed_0900	4.504e-77	271.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4E04G@85010|Pseudonocardiales	201174|Actinobacteria	FP	PFAM Ppx GppA phosphatase	ppx2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158347_k127_565694_14	196162.Noca_0342	1.37e-29	134.0	COG1051@1|root,COG1051@2|Bacteria,2I574@201174|Actinobacteria,4DWXG@85009|Propionibacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_565694_16	1345697.M493_07725	9.147e-22	109.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,1WF5I@129337|Geobacillus	91061|Bacilli	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158347_k127_565694_9	110319.CF8_0499	1.535e-75	273.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,LVIVD
SRR25158347_k127_565694_0	1229780.BN381_290032	6.516e-259	825.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158347_k127_565694_4	1206737.BAGF01000146_gene5807	1.542e-117	387.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4FW4U@85025|Nocardiaceae	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_565694_3	1122138.AQUZ01000090_gene3427	5.258e-124	415.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNJP@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158347_k127_578384_13	1206744.BAGL01000035_gene418	7.115e-105	365.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FWEK@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_578384_43	1120950.KB892823_gene467	6.484e-29	121.0	COG1051@1|root,COG1051@2|Bacteria,2IQEU@201174|Actinobacteria,4DSD6@85009|Propionibacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_578384_54	66897.DJ64_10675	1.166e-10	72.0	2E6WZ@1|root,331GF@2|Bacteria,2IFC6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_578384_6	1463857.JOFZ01000017_gene2486	1.112e-125	422.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158347_k127_578384_44	656024.FsymDg_4044	2.519e-28	121.0	COG1848@1|root,COG1848@2|Bacteria,2GUQC@201174|Actinobacteria,4EWYP@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_578384_59	1048339.KB913029_gene1812	4.739e-06	52.0	2DREV@1|root,33BF4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_578384_63	582515.KR51_00022340	0.0001277	49.0	COG1873@1|root,COG1873@2|Bacteria,1G2EH@1117|Cyanobacteria	1117|Cyanobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158347_k127_578384_12	136273.GY22_10410	5.394e-110	360.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,1W9UJ@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158347_k127_578384_58	936136.ARRT01000007_gene1261	1.251e-08	64.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,2U7BJ@28211|Alphaproteobacteria,4BAKC@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158347_k127_578384_56	877414.ATWA01000011_gene2260	3.279e-09	61.0	COG1826@1|root,COG1826@2|Bacteria,1VHQF@1239|Firmicutes,24QW5@186801|Clostridia	186801|Clostridia	U	mttA/Hcf106 family	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158347_k127_578384_17	266117.Rxyl_0601	4.26e-74	267.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	201174|Actinobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_578384_50	269800.Tfu_0506	2.246e-19	101.0	COG3026@1|root,COG3026@2|Bacteria,2IRR9@201174|Actinobacteria,4EP65@85012|Streptosporangiales	201174|Actinobacteria	T	antisigma factor binding	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB
SRR25158347_k127_578384_60	643562.Daes_0536	3.055e-05	53.0	2DRKB@1|root,33C5H@2|Bacteria,1PDKB@1224|Proteobacteria,43989@68525|delta/epsilon subdivisions,2X4FD@28221|Deltaproteobacteria,2MFP6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158347_k127_578384_27	351607.Acel_1826	1.076e-49	186.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4ESES@85013|Frankiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_578384_49	1048339.KB913029_gene2890	1.024e-20	106.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4ESNB@85013|Frankiales	201174|Actinobacteria	S	PFAM O-methyltransferase, family 3	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
SRR25158347_k127_578384_41	649831.L083_2232	1.627e-30	126.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria,4DE8F@85008|Micromonosporales	201174|Actinobacteria	S	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_578384_4	509635.N824_21320	7.819e-154	514.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158347_k127_578384_15	399550.Smar_0717	4.389e-99	348.0	COG0464@1|root,arCOG01308@2157|Archaea,2XPPI@28889|Crenarchaeota	28889|Crenarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
SRR25158347_k127_578384_11	909613.UO65_3277	2.535e-111	391.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4E0F7@85010|Pseudonocardiales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158347_k127_578384_55	1131269.AQVV01000006_gene471	3.041e-10	67.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR25158347_k127_578384_48	1329516.JPST01000019_gene2690	6.846e-22	100.0	COG5496@1|root,COG5496@2|Bacteria,1UH3T@1239|Firmicutes,4HJC5@91061|Bacilli,27C35@186824|Thermoactinomycetaceae	91061|Bacilli	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_578384_5	1242864.D187_005848	3.002e-147	476.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUBG@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_578384_14	479434.Sthe_2567	1.005e-104	364.0	COG3396@1|root,COG3396@2|Bacteria,2G9AI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158347_k127_578384_57	1313172.YM304_03150	3.467e-09	63.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR25158347_k127_578384_31	479434.Sthe_2569	3.289e-47	179.0	COG3396@1|root,COG3396@2|Bacteria,2G9KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158347_k127_578384_35	292459.STH2483	1.431e-36	151.0	COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,2528Q@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158347_k127_578384_37	1459636.NTE_00025	4.535e-35	149.0	arCOG07536@1|root,arCOG07536@2157|Archaea,41SZB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
SRR25158347_k127_578384_36	1298863.AUEP01000014_gene1672	1.427e-35	155.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4DT76@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_578384_16	479435.Kfla_3441	2.203e-86	310.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DPHM@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158347_k127_578384_2	1313172.YM304_21700	3.235e-218	698.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158347_k127_578384_52	909613.UO65_3501	2.96e-16	87.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4E5GT@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_578384_26	1118054.CAGW01000072_gene1708	8.623e-51	194.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,FAA_hydrolase
SRR25158347_k127_578384_39	1111729.ATYV01000005_gene1189	6.024e-34	150.0	COG0463@1|root,COG0463@2|Bacteria,2I2NK@201174|Actinobacteria,22RMI@1653|Corynebacteriaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	gpgS	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0034641,GO:0040007,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046983,GO:0055086,GO:0071704,GO:1901135,GO:1901360	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158347_k127_578384_23	469383.Cwoe_3796	4.695e-59	226.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CT4V@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158347_k127_578384_38	997296.PB1_10529	2.121e-34	145.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,1ZG6W@1386|Bacillus	91061|Bacilli	S	CoA-binding protein	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158347_k127_578384_45	380749.HY04AAS1_1394	1.238e-23	105.0	COG3411@1|root,COG3411@2|Bacteria,2G541@200783|Aquificae	200783|Aquificae	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158347_k127_578384_42	1321814.HMPREF9089_00672	6.493e-30	132.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25W7R@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158347_k127_578384_53	1197706.AKKK01000004_gene269	6.634e-15	86.0	COG1361@1|root,COG1361@2|Bacteria,2HZGC@201174|Actinobacteria	201174|Actinobacteria	M	Bacterial protein of unknown function (DUF916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF916
SRR25158347_k127_578384_21	479431.Namu_2440	2.292e-64	229.0	COG2197@1|root,COG2197@2|Bacteria,2IJB1@201174|Actinobacteria,4EUUG@85013|Frankiales	201174|Actinobacteria	K	SMART regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_578384_1	2002.JOEQ01000034_gene687	7.243e-229	734.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EMYJ@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_578384_3	2002.JOEQ01000034_gene688	6.196e-216	685.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4EICC@85012|Streptosporangiales	201174|Actinobacteria	CO	ABC transporter transmembrane region	-	-	-	ko:K06148,ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_578384_51	1415780.JPOG01000001_gene3348	4.573e-17	91.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158347_k127_578384_22	42256.RradSPS_1158	1.028e-63	230.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158347_k127_578384_46	247633.GP2143_13336	2.615e-23	108.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,1RRTJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_578384_8	1229780.BN381_310078	9.125e-119	392.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158347_k127_578384_28	452863.Achl_2533	1.249e-48	175.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,1W9H7@1268|Micrococcaceae	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
SRR25158347_k127_578384_30	1176165.CAJD01000019_gene1453	3.227e-47	178.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4FA6Z@85019|Brevibacteriaceae	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158347_k127_578384_0	1229780.BN381_130089	1.314e-232	742.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,3UWBN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158347_k127_578384_25	1169152.AXVD01000003_gene4624	4.413e-53	214.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4FVR6@85025|Nocardiaceae	201174|Actinobacteria	GL	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158347_k127_578384_18	518766.Rmar_1244	4.543e-70	261.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1FIST@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158347_k127_578384_65	383372.Rcas_1279	0.0002252	49.0	2DQ8Q@1|root,335AV@2|Bacteria,2G9D1@200795|Chloroflexi	200795|Chloroflexi	S	pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158347_k127_578384_47	709986.Deima_2998	1.804e-22	113.0	COG3021@1|root,COG3021@2|Bacteria	2|Bacteria	S	interspecies interaction between organisms	-	-	-	ko:K18353	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	Exo_endo_phos
SRR25158347_k127_578384_7	247156.NFA_18650	4.644e-123	410.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4FWQH@85025|Nocardiaceae	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158347_k127_578384_66	324057.Pjdr2_0064	0.0002586	53.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,26STI@186822|Paenibacillaceae	91061|Bacilli	S	ABC-type transport system, periplasmic component surface lipoprotein	yufN	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158347_k127_578384_32	469378.Ccur_12130	1.488e-43	166.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CV42@84998|Coriobacteriia	84998|Coriobacteriia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158347_k127_578384_40	105425.BBPL01000019_gene231	3.481e-33	143.0	COG1853@1|root,COG1853@2|Bacteria,2HP7P@201174|Actinobacteria,2NMWR@228398|Streptacidiphilus	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158347_k127_578384_24	1120948.KB903219_gene643	3.952e-56	208.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DZX7@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	rifO	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158347_k127_578384_33	1120936.KB907211_gene327	1.03e-39	162.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4EI8V@85012|Streptosporangiales	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158347_k127_578384_9	469383.Cwoe_1837	4.532e-116	394.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158347_k127_578384_34	383372.Rcas_3072	1.432e-38	152.0	COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158347_k127_578384_29	588581.Cpap_0672	1.615e-47	181.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WRRF@541000|Ruminococcaceae	186801|Clostridia	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158347_k127_578384_19	502558.EGYY_28840	4.542e-69	254.0	COG0168@1|root,COG0168@2|Bacteria,2HUJP@201174|Actinobacteria,4CUYG@84998|Coriobacteriia	84998|Coriobacteriia	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158347_k127_578384_61	697281.Mahau_2865	9.32e-05	53.0	2EDRU@1|root,337MD@2|Bacteria,1VIEE@1239|Firmicutes,24P45@186801|Clostridia,42IRG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_578384_10	1499689.CCNN01000014_gene3136	1.453e-115	389.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,36E52@31979|Clostridiaceae	186801|Clostridia	P	potassium uptake protein TrkH	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158347_k127_578384_20	926550.CLDAP_25410	6.271e-65	230.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi	200795|Chloroflexi	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158347_k127_602374_2	547163.BN979_00432	8.114e-09	61.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,232ST@1762|Mycobacteriaceae	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158347_k127_602374_0	1146883.BLASA_4010	6.529e-144	472.0	COG4262@1|root,COG4262@2|Bacteria,2I372@201174|Actinobacteria,4EUU4@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158347_k127_602374_1	443598.AUFA01000041_gene6138	1.231e-23	118.0	COG1252@1|root,COG1252@2|Bacteria,1N2QQ@1224|Proteobacteria,2TUT3@28211|Alphaproteobacteria,3JS5F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_602374_3	1235803.C825_00892	0.0003189	45.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,2FM1T@200643|Bacteroidia,22XEW@171551|Porphyromonadaceae	976|Bacteroidetes	J	Fe-S oxidoreductase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158347_k127_60599_5	404589.Anae109_3818	1.075e-11	71.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158347_k127_60599_2	710696.Intca_2717	1.155e-54	218.0	COG2385@1|root,COG2385@2|Bacteria,2I2J0@201174|Actinobacteria,4FFQU@85021|Intrasporangiaceae	201174|Actinobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SpoIID,VCBS
SRR25158347_k127_60599_6	1246474.ANBE01000009_gene457	9.378e-09	68.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4EJ4G@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158347_k127_60599_1	479434.Sthe_0859	2.282e-74	263.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,27XQE@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_60599_3	1313304.CALK_0260	2.862e-30	137.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_60599_4	309801.trd_1297	1.553e-24	118.0	COG5650@1|root,COG5650@2|Bacteria,2GB8F@200795|Chloroflexi,27Y1V@189775|Thermomicrobia	189775|Thermomicrobia	S	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_60599_0	1380354.JIAN01000006_gene1155	8.543e-174	570.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRR25158347_k127_620902_1	1226994.AMZB01000138_gene5655	8.494e-59	231.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1YDN2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iECNA114_1301.ECNA114_3561	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_620902_0	1160707.AJIK01000014_gene2665	1.712e-68	241.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,26D96@186818|Planococcaceae	91061|Bacilli	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158347_k127_625680_1	67373.JOBF01000007_gene2267	1.034e-51	187.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	fabK	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158347_k127_625680_0	1122182.KB903833_gene5401	5.39e-99	365.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158347_k127_648736_10	351607.Acel_1211	2.954e-76	262.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4EXF1@85013|Frankiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158347_k127_648736_13	1157637.KB892124_gene711	1.189e-59	226.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158347_k127_648736_7	1050202.KB913024_gene1197	2.661e-95	332.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,409V4@622450|Actinopolysporales	201174|Actinobacteria	S	Amidohydrolase family	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158347_k127_648736_4	235985.BBPN01000020_gene6477	5.899e-140	459.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,2NHRD@228398|Streptacidiphilus	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_648736_23	935863.AWZR01000001_gene1775	0.0001804	54.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158347_k127_648736_5	2002.JOEQ01000002_gene4381	8.36e-117	389.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4EFV3@85012|Streptosporangiales	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158347_k127_648736_8	1229780.BN381_170034	3.168e-95	337.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,3UWFB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158347_k127_648736_15	552811.Dehly_0143	3.257e-40	161.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,34CPQ@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158347_k127_648736_21	1192034.CAP_1844	4.876e-14	84.0	COG0247@1|root,COG0247@2|Bacteria,1QA7J@1224|Proteobacteria,434VW@68525|delta/epsilon subdivisions,2X91N@28221|Deltaproteobacteria,2Z1GG@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
SRR25158347_k127_648736_6	1120936.KB907211_gene465	2.026e-101	347.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4EHBF@85012|Streptosporangiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	eapA	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158347_k127_648736_0	397278.JOJN01000004_gene1468	1.739e-242	786.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4DN1B@85009|Propionibacteriales	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158347_k127_648736_14	656024.FsymDg_2210	2.504e-57	210.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4ESEG@85013|Frankiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158347_k127_648736_22	1165841.SULAR_07505	4.942e-08	59.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42VNG@68525|delta/epsilon subdivisions,2YQ9F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158347_k127_648736_19	351607.Acel_1202	3.34e-15	81.0	2BZPH@1|root,33EX8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_648736_2	356851.JOAN01000023_gene4821	1.509e-209	669.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4DA66@85008|Micromonosporales	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158347_k127_648736_11	585531.HMPREF0063_10748	2.416e-74	257.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4DMZ3@85009|Propionibacteriales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158347_k127_648736_9	408672.NBCG_01143	8.548e-78	269.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4DPD6@85009|Propionibacteriales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158347_k127_648736_16	1000565.METUNv1_03031	6.069e-31	140.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,2VKTE@28216|Betaproteobacteria,2KXVP@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158347_k127_648736_17	1298863.AUEP01000008_gene1321	4.703e-21	98.0	COG2197@1|root,COG3829@1|root,COG2197@2|Bacteria,COG3829@2|Bacteria,2IDZS@201174|Actinobacteria	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,Response_reg
SRR25158347_k127_648736_20	134676.ACPL_5244	1.258e-14	78.0	2E9C2@1|root,333JS@2|Bacteria,2IQ5V@201174|Actinobacteria,4DFMG@85008|Micromonosporales	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158347_k127_648736_3	269800.Tfu_1796	9.858e-185	589.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4EGNP@85012|Streptosporangiales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158347_k127_648736_1	1048339.KB913029_gene4197	1.544e-237	751.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4ERPJ@85013|Frankiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158347_k127_648736_12	1122138.AQUZ01000001_gene1636	6.979e-74	262.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4DNGH@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158347_k127_648736_18	1122247.C731_3324	1.204e-16	82.0	COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria	201174|Actinobacteria	D	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158347_k127_685408_0	935866.JAER01000005_gene168	5.446e-63	237.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4DMYV@85009|Propionibacteriales	201174|Actinobacteria	DM	AAA domain	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,ParA,Wzz
SRR25158347_k127_693278_1	1386089.N865_00345	7.069e-98	346.0	COG3103@1|root,COG3103@2|Bacteria,2I3C9@201174|Actinobacteria	201174|Actinobacteria	T	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158347_k127_693278_2	43759.JNWK01000010_gene4767	5.914e-52	188.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_693278_0	1415780.JPOG01000001_gene2311	1.559e-130	443.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,1X5NC@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_695523_1	1957.JODX01000015_gene1376	3.38e-81	284.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria	201174|Actinobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158347_k127_695523_2	356851.JOAN01000003_gene1404	5.406e-72	252.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4D8HJ@85008|Micromonosporales	201174|Actinobacteria	P	cobalt ABC transporter, inner membrane subunit CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158347_k127_695523_0	397278.JOJN01000007_gene3107	1.219e-97	337.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DN9V@85009|Propionibacteriales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158347_k127_695523_3	1313172.YM304_33500	6.599e-59	232.0	COG1305@1|root,COG1721@1|root,COG1305@2|Bacteria,COG1721@2|Bacteria,2HH1I@201174|Actinobacteria,4CP1R@84992|Acidimicrobiia	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF58,Transglut_core
SRR25158347_k127_695523_4	1229780.BN381_140022	6.979e-05	53.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,3UXJ7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158347_k127_70449_3	479432.Sros_9385	1.808e-32	136.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4EIK1@85012|Streptosporangiales	201174|Actinobacteria	M	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158347_k127_70449_1	1313172.YM304_42850	4.722e-89	320.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CMSR@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_70449_0	1229203.KI301992_gene2680	2.313e-90	308.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,3UWJE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	ParB-like nuclease domain	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158347_k127_70449_2	189425.PGRAT_13815	3.083e-35	139.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,26QCU@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158347_k127_724435_0	398512.JQKC01000016_gene2841	1.167e-69	266.0	COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,25EWP@186801|Clostridia	186801|Clostridia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158347_k127_724435_1	243164.DET0872	6.61e-58	216.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,34D1E@301297|Dehalococcoidia	301297|Dehalococcoidia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158347_k127_724435_4	1118059.CAHC01000006_gene38	5.644e-35	155.0	COG2247@1|root,COG2247@2|Bacteria,1V6RJ@1239|Firmicutes,24YDM@186801|Clostridia,3WDCX@538999|Clostridiales incertae sedis	186801|Clostridia	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,NEAT
SRR25158347_k127_724435_2	446471.Xcel_2201	1.623e-43	183.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_724435_3	713586.KB900536_gene1289	3.784e-42	175.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Trans_reg_C
SRR25158347_k127_727133_9	374847.Kcr_0408	1.511e-10	74.0	COG1233@1|root,arCOG01521@2157|Archaea	2157|Archaea	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158347_k127_727133_0	1415780.JPOG01000001_gene3335	1.624e-191	613.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria,1X7J4@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_727133_2	1056816.JAFQ01000004_gene2071	1.022e-135	438.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4G007@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158347_k127_727133_1	68170.KL590499_gene4927	3.09e-174	620.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4E8ZQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
SRR25158347_k127_727133_4	1229780.BN381_210048	7.385e-72	249.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,3UXQY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158347_k127_727133_5	521096.Tpau_2352	6.376e-65	226.0	COG3832@1|root,COG3832@2|Bacteria,2IPH4@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Polyketide_cyc2
SRR25158347_k127_727133_3	479434.Sthe_3373	1.068e-78	277.0	COG0654@1|root,COG0654@2|Bacteria,2G66I@200795|Chloroflexi	200795|Chloroflexi	C	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158347_k127_727133_7	485913.Krac_10395	2.267e-45	178.0	COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_727133_6	797209.ZOD2009_15786	1.134e-54	194.0	COG5649@1|root,2N58B@2157|Archaea	2157|Archaea	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158347_k127_727133_8	1536772.R70723_14680	1.396e-40	171.0	COG1357@1|root,COG1357@2|Bacteria,1V8FP@1239|Firmicutes,4HHEX@91061|Bacilli,26TI8@186822|Paenibacillaceae	91061|Bacilli	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158347_k127_741558_15	222534.KB893749_gene4492	1.253e-58	229.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158347_k127_741558_20	1033734.CAET01000041_gene390	2.614e-39	168.0	COG0741@1|root,COG2247@1|root,COG0741@2|Bacteria,COG2247@2|Bacteria,1UK2U@1239|Firmicutes,4HDEW@91061|Bacilli,1ZPWE@1386|Bacillus	91061|Bacilli	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,SLT
SRR25158347_k127_741558_6	644966.Tmar_1506	5.341e-126	417.0	COG2132@1|root,COG2132@2|Bacteria,1V0S4@1239|Firmicutes,24NII@186801|Clostridia	186801|Clostridia	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
SRR25158347_k127_741558_24	187272.Mlg_1887	1.055e-21	100.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WY2N@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158347_k127_741558_12	443906.CMM_1411	2.068e-80	290.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4FM1Z@85023|Microbacteriaceae	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_741558_10	644283.Micau_4235	1.087e-86	297.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,4D8HD@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
SRR25158347_k127_741558_2	1476876.JOJO01000003_gene5466	2.555e-241	767.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_741558_25	1485544.JQKP01000005_gene339	2.015e-20	99.0	COG0746@1|root,COG0746@2|Bacteria,1PJ8F@1224|Proteobacteria,2VYU6@28216|Betaproteobacteria,44WA2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	MobA-like NTP transferase domain	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158347_k127_741558_19	66373.JOFQ01000006_gene3096	1.772e-42	167.0	COG0596@1|root,COG0596@2|Bacteria,2I2VI@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_741558_1	710111.FraQA3DRAFT_3179	3.253e-256	815.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4ES10@85013|Frankiales	201174|Actinobacteria	E	PFAM Peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158347_k127_741558_27	1485545.JQLW01000006_gene493	1.811e-13	75.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria	1224|Proteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158347_k127_741558_11	1395571.TMS3_0118455	3.639e-81	284.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,1RSCI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_741558_3	935866.JAER01000009_gene774	1.442e-204	654.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DPPW@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD3	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_741558_9	1229780.BN381_50061	3.305e-87	305.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,3UWHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158347_k127_741558_5	1246484.D479_10536	8.987e-127	418.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3NDU5@45667|Halobacillus	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158347_k127_741558_13	1229780.BN381_10284	8.856e-80	283.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,3UWH6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158347_k127_741558_22	1538295.JY96_06200	5.605e-30	133.0	2E963@1|root,333ES@2|Bacteria,1QW4F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
SRR25158347_k127_741558_14	880072.Desac_2808	9.865e-65	239.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2MRAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158347_k127_741558_21	1313172.YM304_29420	1.618e-36	149.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_741558_16	886293.Sinac_2594	5.349e-56	209.0	COG3253@1|root,COG3253@2|Bacteria,2IYDD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158347_k127_741558_8	661478.OP10G_3575	4.878e-89	298.0	COG0588@1|root,COG0588@2|Bacteria	2|Bacteria	G	phosphoglycerate mutase activity	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158347_k127_741558_18	397278.JOJN01000003_gene1692	3.012e-47	184.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2IF18@201174|Actinobacteria,4DN6C@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158347_k127_741558_26	1122939.ATUD01000010_gene2897	2.963e-19	102.0	COG5470@1|root,COG5470@2|Bacteria,2IAYV@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4393
SRR25158347_k127_741558_4	1121935.AQXX01000104_gene363	2.42e-134	443.0	COG4399@1|root,COG4399@2|Bacteria,1R42C@1224|Proteobacteria,1RPWG@1236|Gammaproteobacteria,1XNGD@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_741558_0	1229780.BN381_430007	0.0	1028.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,3UW9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158347_k127_741558_23	1033730.CAHG01000013_gene1290	2.038e-22	106.0	COG1595@1|root,COG1595@2|Bacteria,2IRIQ@201174|Actinobacteria,4DS0M@85009|Propionibacteriales	201174|Actinobacteria	K	SatD family (SatD)	-	-	-	-	-	-	-	-	-	-	-	-	SatD
SRR25158347_k127_741558_7	1043493.BBLU01000008_gene519	3.674e-102	338.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158347_k127_741558_17	1313172.YM304_41590	9.919e-54	196.0	COG0218@1|root,COG0218@2|Bacteria	2|Bacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158347_k127_744632_11	1123320.KB889585_gene1891	2.803e-30	123.0	COG1960@1|root,COG1960@2|Bacteria,2I8MN@201174|Actinobacteria	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158347_k127_744632_14	1476876.JOJO01000045_gene1272	1.419e-17	97.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR25158347_k127_744632_10	675635.Psed_4615	6.576e-44	170.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DXC6@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_744632_8	644283.Micau_1064	3.389e-57	207.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4DD94@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_744632_5	561175.KB894094_gene1802	1.517e-86	299.0	COG2141@1|root,COG2141@2|Bacteria,2GJT1@201174|Actinobacteria,4EHCK@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_744632_6	471852.Tcur_2757	3.112e-71	249.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria,4EK3C@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_744632_12	1440774.Y900_021100	1.33e-25	124.0	COG5517@1|root,COG5517@2|Bacteria,2IFNT@201174|Actinobacteria,239AB@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158347_k127_744632_0	1123257.AUFV01000001_gene1648	2.443e-134	450.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,1X50C@135614|Xanthomonadales	135614|Xanthomonadales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
SRR25158347_k127_744632_1	1394178.AWOO02000020_gene7376	4.98e-117	394.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4EHV1@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,PD40
SRR25158347_k127_744632_2	298655.KI912266_gene5570	1.047e-115	380.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4EVXM@85013|Frankiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158347_k127_744632_4	1415780.JPOG01000001_gene1918	6.114e-106	363.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria,1X4JX@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_744632_9	247634.GPB2148_2815	1.494e-48	188.0	COG1960@1|root,COG1960@2|Bacteria,1P4V3@1224|Proteobacteria,1RZBS@1236|Gammaproteobacteria,1J4FZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158347_k127_744632_3	2002.JOEQ01000001_gene4848	4.983e-111	378.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_744632_7	591157.SSLG_00954	9.873e-62	216.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_813128_1	543632.JOJL01000005_gene4761	3.233e-52	205.0	COG1404@1|root,COG1404@2|Bacteria,2IAS7@201174|Actinobacteria,4DHP7@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158347_k127_813128_0	391625.PPSIR1_25986	1.97e-84	301.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169,iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
SRR25158347_k127_813128_2	1056816.JAFQ01000004_gene168	2.03e-34	139.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,4G94I@85025|Nocardiaceae	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158347_k127_829027_11	1380347.JNII01000005_gene3039	6.775e-46	188.0	COG0642@1|root,COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9,Response_reg,STAS_2,SpoIIE
SRR25158347_k127_829027_16	1033740.CAEW01000031_gene2037	2.089e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,4HP2I@91061|Bacilli,26I5B@186818|Planococcaceae	91061|Bacilli	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158347_k127_829027_10	521003.COLINT_02253	4.592e-53	198.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CUM2@84998|Coriobacteriia	84998|Coriobacteriia	K	RNA polymerase sigma-70 factor, sigma-B F G subfamily	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_829027_1	1313172.YM304_07450	7.408e-255	807.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158347_k127_829027_2	398767.Glov_3266	6.28e-188	617.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158347_k127_829027_5	1211815.CBYP010000028_gene1090	2.727e-132	445.0	COG0125@1|root,COG0477@1|root,COG0125@2|Bacteria,COG0477@2|Bacteria,2GNTI@201174|Actinobacteria,4ES48@85013|Frankiales	201174|Actinobacteria	EFGP	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR25158347_k127_829027_13	561175.KB894093_gene3554	4.854e-28	129.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4EG3M@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158347_k127_829027_12	1278073.MYSTI_07395	3.579e-30	138.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C1T@68525|delta/epsilon subdivisions,2X7CE@28221|Deltaproteobacteria,2Z3MI@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_829027_0	644966.Tmar_2159	6.268e-302	949.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WCC8@538999|Clostridiales incertae sedis	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158347_k127_829027_15	622637.KE124774_gene1613	1.532e-14	83.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,2UIK4@28211|Alphaproteobacteria,370CV@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
SRR25158347_k127_829027_4	58123.JOFJ01000014_gene5030	7.262e-153	507.0	COG3259@1|root,COG3259@2|Bacteria,2GQ33@201174|Actinobacteria,4EGG1@85012|Streptosporangiales	201174|Actinobacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SRR25158347_k127_829027_7	1043493.BBLU01000015_gene1112	6.217e-110	376.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
SRR25158347_k127_829027_9	1122221.JHVI01000016_gene1615	4.5e-79	278.0	COG0543@1|root,COG0543@2|Bacteria,1WKS1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
SRR25158347_k127_829027_14	644283.Micau_2386	4.075e-24	115.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria,4DF04@85008|Micromonosporales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158347_k127_829027_8	298655.KI912266_gene2852	3.304e-105	353.0	COG0247@1|root,COG0247@2|Bacteria,2I3IR@201174|Actinobacteria,4EUJ2@85013|Frankiales	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRR25158347_k127_829027_17	1043493.BBLU01000014_gene1319	9.705e-08	64.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158347_k127_829027_18	1121406.JAEX01000002_gene922	0.0003533	51.0	COG2050@1|root,COG2050@2|Bacteria,1NGFY@1224|Proteobacteria,42UY5@68525|delta/epsilon subdivisions,2WSY5@28221|Deltaproteobacteria,2MCPJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRR25158347_k127_829027_6	1096756.ATKN01000017_gene1412	1.193e-113	371.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,1WCGJ@1268|Micrococcaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_829027_3	1254432.SCE1572_04615	1.136e-161	528.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42MT4@68525|delta/epsilon subdivisions,2WKZD@28221|Deltaproteobacteria,2Z34N@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158347_k127_859642_9	234267.Acid_2380	2.395e-13	83.0	COG2133@1|root,COG3292@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1906,Glyco_hydro_18,Malectin,PA14,SLH,VCBS
SRR25158347_k127_859642_3	926569.ANT_05420	1.896e-58	214.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158347_k127_859642_2	1382356.JQMP01000003_gene1700	3.282e-65	235.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,27XY2@189775|Thermomicrobia	189775|Thermomicrobia	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158347_k127_859642_1	1123320.KB889737_gene5363	4.201e-70	251.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158347_k127_859642_0	1445613.JALM01000099_gene4539	6.293e-81	284.0	COG1940@1|root,COG1940@2|Bacteria,2GIU4@201174|Actinobacteria,4DXQZ@85010|Pseudonocardiales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,MarR_2,ROK
SRR25158347_k127_859642_7	1123368.AUIS01000023_gene896	2.077e-30	139.0	COG2267@1|root,COG2267@2|Bacteria,1QYVT@1224|Proteobacteria	1224|Proteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_859642_5	1089548.KI783301_gene2561	4.016e-46	183.0	COG3525@1|root,COG3525@2|Bacteria,1TSQE@1239|Firmicutes,4HEXS@91061|Bacilli	91061|Bacilli	G	beta-N-acetylglucosaminidase	hyl	-	3.2.1.35	ko:K01197	ko00531,ko01100,map00531,map01100	M00076,M00077	R07824,R07825,R10905	-	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	-	-	F5_F8_type_C,Glyco_hydro_20b,NAGidase
SRR25158347_k127_859642_10	1449976.KALB_1375	3.406e-13	78.0	COG1940@1|root,COG1940@2|Bacteria,2IPHU@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158347_k127_859642_12	1206726.BAFV01000039_gene2636	3.624e-07	63.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4FZUX@85025|Nocardiaceae	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_859642_11	266834.SMc03810	2.449e-11	74.0	COG2267@1|root,COG2267@2|Bacteria,1QXBY@1224|Proteobacteria,2TX89@28211|Alphaproteobacteria,4BBSI@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_859642_8	1120950.KB892707_gene4625	1.025e-15	91.0	COG3356@1|root,COG3356@2|Bacteria,2I6IM@201174|Actinobacteria,4DW56@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SRR25158347_k127_859642_4	525904.Tter_0406	5.509e-55	209.0	COG0673@1|root,COG0673@2|Bacteria,2NQ2X@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158347_k127_859642_6	1116232.AHBF01000139_gene1782	1.471e-31	131.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	stsA	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158347_k127_865338_4	485913.Krac_2634	7.002e-21	104.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS
SRR25158347_k127_865338_1	1121272.KB903290_gene4684	9.361e-55	206.0	2CBE1@1|root,32RT5@2|Bacteria,2IQDS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_865338_0	494419.ALPM01000066_gene2127	1.465e-123	428.0	COG2267@1|root,COG2267@2|Bacteria,2I9JC@201174|Actinobacteria	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_865338_2	1122138.AQUZ01000016_gene283	1.873e-32	130.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158347_k127_865338_3	1123256.KB907950_gene3185	8.84e-26	113.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,1X5NC@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_90421_4	1380390.JIAT01000010_gene4387	1.067e-167	562.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158347_k127_90421_16	222534.KB893761_gene3562	1.088e-69	252.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4EU5A@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158347_k127_90421_34	1184609.KILIM_008_00120	1.656e-11	70.0	COG1396@1|root,COG1396@2|Bacteria,2IMPS@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158347_k127_90421_22	419947.MRA_1057	1.492e-49	190.0	COG4861@1|root,COG4861@2|Bacteria,2H1DQ@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2
SRR25158347_k127_90421_29	1454010.JEOE01000008_gene1864	2.372e-24	114.0	28HCU@1|root,2Z7PM@2|Bacteria,2GPHN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_90421_31	1313172.YM304_28740	1.218e-18	100.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CP53@84992|Acidimicrobiia	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158347_k127_90421_24	1463921.JODF01000021_gene3331	5.856e-45	175.0	COG1024@1|root,COG1024@2|Bacteria,2IEXB@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA3_1	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_90421_32	469371.Tbis_0717	1.28e-18	100.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4DYHE@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158347_k127_90421_38	1150399.AQYK01000001_gene1659	5.811e-05	52.0	2CNM1@1|root,32SHB@2|Bacteria,2GKWT@201174|Actinobacteria,4FS3H@85023|Microbacteriaceae	201174|Actinobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
SRR25158347_k127_90421_11	298655.KI912266_gene542	1.554e-118	394.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158347_k127_90421_23	452637.Oter_3715	1.326e-46	175.0	COG3132@1|root,COG3132@2|Bacteria,46VIH@74201|Verrucomicrobia,3K85I@414999|Opitutae	414999|Opitutae	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SRR25158347_k127_90421_20	215803.DB30_1826	2.676e-51	196.0	COG0451@1|root,COG0451@2|Bacteria,1PEGY@1224|Proteobacteria,4345A@68525|delta/epsilon subdivisions,2X3ZH@28221|Deltaproteobacteria,2YXPP@29|Myxococcales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158347_k127_90421_39	358823.DF19_34150	0.0003294	53.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158347_k127_90421_8	743718.Isova_0817	4.04e-147	496.0	COG0507@1|root,COG0507@2|Bacteria,2GIX1@201174|Actinobacteria,4F56S@85017|Promicromonosporaceae	201174|Actinobacteria	L	Viral (Superfamily 1) RNA helicase	recD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
SRR25158347_k127_90421_1	469383.Cwoe_3373	5.151e-277	901.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158347_k127_90421_0	469383.Cwoe_3372	7.729e-313	996.0	COG1330@1|root,COG1330@2|Bacteria,2GNVB@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
SRR25158347_k127_90421_9	1120934.KB894443_gene4246	9.294e-131	434.0	COG1020@1|root,COG1020@2|Bacteria,2GPHZ@201174|Actinobacteria,4E19T@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158347_k127_90421_36	1121926.AXWO01000003_gene647	2.978e-09	70.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_90421_28	883078.HMPREF9695_03130	1.041e-25	120.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2TSIQ@28211|Alphaproteobacteria,3JR6D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158347_k127_90421_14	479434.Sthe_3113	7.113e-86	318.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2G7T8@200795|Chloroflexi,27ZCX@189775|Thermomicrobia	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158347_k127_90421_18	1449069.JMLO01000021_gene3008	8.16e-58	217.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4FW36@85025|Nocardiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_90421_30	1380390.JIAT01000010_gene4718	9.932e-22	108.0	COG3835@1|root,COG3835@2|Bacteria	2|Bacteria	KT	positive regulation of transcription, DNA-templated	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,HTH_30
SRR25158347_k127_90421_6	414996.IL38_17980	7.428e-152	513.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,408KZ@622450|Actinopolysporales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_90421_15	1122622.ATWJ01000007_gene1476	7.231e-72	252.0	COG2267@1|root,COG2267@2|Bacteria,2HX7Q@201174|Actinobacteria,4FFJN@85021|Intrasporangiaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_90421_33	268739.Nmlp_3754	5.155e-16	91.0	arCOG06923@1|root,arCOG06923@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158347_k127_90421_7	1121861.KB899927_gene1579	1.931e-151	495.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,2JQ9A@204441|Rhodospirillales	204441|Rhodospirillales	F	formate-tetrahydrofolate ligase activity	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158347_k127_90421_3	518766.Rmar_2202	1.588e-182	587.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJSN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_90421_27	1403313.AXBR01000013_gene1347	6.851e-31	141.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus	91061|Bacilli	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158347_k127_90421_5	1122939.ATUD01000016_gene1882	2.19e-161	519.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4CQP7@84995|Rubrobacteria	84995|Rubrobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_90421_26	446468.Ndas_4768	8.725e-37	150.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4EGC3@85012|Streptosporangiales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158347_k127_90421_19	105422.BBPM01000003_gene5646	4.747e-54	195.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria,2NI8I@228398|Streptacidiphilus	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158347_k127_90421_17	1304275.C41B8_09566	3.19e-58	216.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1S1J7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Cardiolipin synthetase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158347_k127_90421_35	1380390.JIAT01000011_gene2297	6.083e-11	73.0	COG1714@1|root,COG1714@2|Bacteria,2HRTA@201174|Actinobacteria,4CTWR@84995|Rubrobacteria	84995|Rubrobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158347_k127_90421_13	1463820.JOGW01000030_gene6557	3.163e-90	339.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
SRR25158347_k127_90421_2	63737.Npun_R0589	1.059e-202	644.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1HMXM@1161|Nostocales	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158347_k127_90421_12	479434.Sthe_0598	1.975e-105	383.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158347_k127_90421_25	1210046.B277_02094	9.768e-40	164.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4FGQH@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidoglycan-binding	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158347_k127_90421_10	1123368.AUIS01000034_gene1360	1.372e-127	443.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
SRR25158347_k127_90421_21	929712.KI912613_gene2392	1.933e-50	188.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CQJI@84995|Rubrobacteria	84995|Rubrobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158347_k127_928945_5	443255.SCLAV_2287	4.755e-122	402.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria	201174|Actinobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158347_k127_928945_2	469371.Tbis_2053	1.81e-206	660.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4E0SI@85010|Pseudonocardiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158347_k127_928945_6	351607.Acel_1333	4.748e-118	415.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4ERXK@85013|Frankiales	201174|Actinobacteria	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158347_k127_928945_10	351607.Acel_1332	5.491e-11	68.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4ET7N@85013|Frankiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR25158347_k127_928945_1	35754.JNYJ01000001_gene7425	7.335e-208	679.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4DA2Y@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158347_k127_928945_9	1122622.ATWJ01000010_gene1428	2.182e-24	118.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4FGUB@85021|Intrasporangiaceae	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158347_k127_928945_7	1196323.ALKF01000198_gene2437	5.142e-61	224.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,26Q9M@186822|Paenibacillaceae	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158347_k127_928945_8	1121430.JMLG01000021_gene1382	1.889e-55	212.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158347_k127_928945_0	1304865.JAGF01000001_gene3210	1.683e-213	677.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158347_k127_928945_3	1095767.CAHD01000205_gene848	1.344e-153	503.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158347_k127_928945_4	1304865.JAGF01000001_gene3208	2.49e-142	465.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system	tapC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158347_k127_928945_11	266117.Rxyl_1158	8.019e-07	51.0	COG4968@1|root,COG4968@2|Bacteria,2I4BD@201174|Actinobacteria,4CU66@84995|Rubrobacteria	84995|Rubrobacteria	NU	Cell motility and secretion Intracellular trafficking and secretion	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158347_k127_950737_21	1121946.AUAX01000031_gene1020	3.964e-30	129.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_950737_26	1133849.O3I_005040	9.741e-09	66.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4FWK1@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158347_k127_950737_7	1121877.JQKF01000048_gene761	9.148e-76	264.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4CNWF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158347_k127_950737_18	1304865.JAGF01000001_gene2416	4.424e-48	186.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158347_k127_950737_24	1177594.MIC448_1880004	8.606e-23	114.0	COG4251@1|root,COG4251@2|Bacteria,2GK25@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
SRR25158347_k127_950737_20	211165.AJLN01000119_gene901	1.066e-41	178.0	COG0642@1|root,COG0784@1|root,COG3447@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,1G09B@1117|Cyanobacteria,1JJQ7@1189|Stigonemataceae	1117|Cyanobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_950737_23	861299.J421_1917	3.451e-24	121.0	COG0642@1|root,COG2205@2|Bacteria,1ZTRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158347_k127_950737_19	219305.MCAG_02184	2.616e-46	173.0	COG0745@1|root,COG0745@2|Bacteria,2I2VM@201174|Actinobacteria,4DCXS@85008|Micromonosporales	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_950737_10	797210.Halxa_2975	1.434e-65	245.0	COG3413@1|root,arCOG06712@1|root,arCOG07605@1|root,arCOG02278@2157|Archaea,arCOG06712@2157|Archaea,arCOG07605@2157|Archaea,2XW2Z@28890|Euryarchaeota,23UFJ@183963|Halobacteria	183963|Halobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158347_k127_950737_8	1504672.669785122	7.589e-70	244.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158347_k127_950737_13	1121918.ARWE01000001_gene494	1.019e-54	201.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria	1224|Proteobacteria	S	Metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158347_k127_950737_17	1122137.AQXF01000001_gene2614	4.099e-48	179.0	COG1309@1|root,COG1309@2|Bacteria,1NA9R@1224|Proteobacteria,2UGFK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_950737_0	1043493.BBLU01000015_gene1146	3.238e-247	786.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158347_k127_950737_1	196162.Noca_0122	3.514e-247	769.0	COG1773@1|root,COG3239@1|root,COG1773@2|Bacteria,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,4DNRV@85009|Propionibacteriales	201174|Actinobacteria	C	Rubredoxin	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
SRR25158347_k127_950737_12	1122609.AUGT01000020_gene1007	6.912e-64	229.0	COG1309@1|root,COG1309@2|Bacteria,2GMDA@201174|Actinobacteria,4DQT1@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_950737_3	1229780.BN381_100081	2.864e-127	419.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249	2.1.1.254,2.1.1.295,2.1.1.79,2.7.11.1	ko:K00574,ko:K07154,ko:K14369,ko:K15257,ko:K18534	ko00130,ko00522,ko01100,ko01110,ko01130,map00130,map00522,map01100,map01110,map01130	M00112,M00774	R05520,R05532,R07501,R10709,R10710	RC00003,RC01324,RC01662	ko00000,ko00001,ko00002,ko01000,ko01001,ko01008,ko02048,ko03016	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158347_k127_950737_15	1313172.YM304_34240	3.311e-53	201.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4CNZJ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158347_k127_950737_22	1385510.N781_03290	2.727e-24	110.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,2YAF9@289201|Pontibacillus	91061|Bacilli	O	Cytochrome C biogenesis protein	yneN	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158347_k127_950737_4	1313172.YM304_34420	4.566e-102	343.0	COG2267@1|root,COG2267@2|Bacteria,2HF8H@201174|Actinobacteria,4CNE1@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_950737_16	1292020.H483_0106130	1.531e-49	194.0	COG4270@1|root,COG4270@2|Bacteria,2IKKP@201174|Actinobacteria	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158347_k127_950737_5	396595.TK90_0253	3.59e-84	289.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158347_k127_950737_14	365528.KB891219_gene1082	2.911e-53	206.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158347_k127_950737_25	509191.AEDB02000093_gene3466	1.062e-18	94.0	COG5012@1|root,COG5012@2|Bacteria,1V5EH@1239|Firmicutes,24HIB@186801|Clostridia,3WMC9@541000|Ruminococcaceae	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158347_k127_950737_11	1286171.EAL2_c21260	2.42e-64	239.0	COG4591@1|root,COG4591@2|Bacteria,1TQ8J@1239|Firmicutes,24BJ2@186801|Clostridia	186801|Clostridia	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158347_k127_950737_9	926692.AZYG01000079_gene342	4.114e-66	232.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158347_k127_950737_2	518766.Rmar_2613	3.298e-141	460.0	COG0438@1|root,COG0438@2|Bacteria,4NIWP@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_950737_6	1142394.PSMK_07550	7.711e-83	279.0	COG2152@1|root,COG2152@2|Bacteria,2IYI2@203682|Planctomycetes	203682|Planctomycetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158347_k127_9528_2	44060.JODL01000006_gene1356	1.862e-74	256.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158347_k127_9528_3	1283299.AUKG01000002_gene4193	7.788e-40	169.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4CQZX@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158347_k127_9528_0	1382356.JQMP01000003_gene1584	3.997e-234	755.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158347_k127_9528_1	1048339.KB913029_gene4363	3.953e-100	334.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4ERKZ@85013|Frankiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158347_k127_960263_1	196162.Noca_4679	2.03e-145	480.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	CARDB,CHU_C,DUF11,PKD,Peptidase_M30
SRR25158347_k127_960263_5	479433.Caci_8860	2.536e-45	181.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158347_k127_960263_6	1297742.A176_07647	2.188e-36	151.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
SRR25158347_k127_960263_2	1229780.BN381_40090	1.325e-91	324.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_960263_4	1114856.C496_21387	9.149e-51	201.0	COG1233@1|root,arCOG01521@2157|Archaea,2XU1W@28890|Euryarchaeota,23TP0@183963|Halobacteria	183963|Halobacteria	Q	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158347_k127_960263_8	118161.KB235922_gene4122	6.984e-08	64.0	COG5401@1|root,COG5401@2|Bacteria,1G6M2@1117|Cyanobacteria,3VJS5@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SRR25158347_k127_960263_9	1469245.JFBG01000033_gene1406	2.192e-05	52.0	2DMDR@1|root,32QSY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
SRR25158347_k127_960263_0	1157943.KB892705_gene2248	5.647e-164	530.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158347_k127_960263_7	700508.D174_12685	8.04e-26	117.0	COG3427@1|root,COG3427@2|Bacteria,2I3MD@201174|Actinobacteria,2361M@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_960263_3	1122622.ATWJ01000014_gene448	6.909e-81	272.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158347_k127_966168_23	882082.SaccyDRAFT_5008	2.019e-30	122.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4E0FG@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158347_k127_966168_5	1146883.BLASA_3839	4.403e-115	391.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4ERZ8@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
SRR25158347_k127_966168_19	1191523.MROS_0929	9.79e-37	151.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Imp-YgjV
SRR25158347_k127_966168_10	404589.Anae109_3942	3.224e-82	286.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria,2YUHP@29|Myxococcales	28221|Deltaproteobacteria	E	succinyl-diaminopimelate desuccinylase	dapE2	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158347_k127_966168_3	648996.Theam_1246	8.129e-119	390.0	COG2171@1|root,COG2171@2|Bacteria,2G3KV@200783|Aquificae	200783|Aquificae	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158347_k127_966168_9	1229780.BN381_130115	1.217e-83	289.0	COG2035@1|root,COG2035@2|Bacteria,2I8HU@201174|Actinobacteria,3UXEC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
SRR25158347_k127_966168_32	561175.KB894095_gene2313	4.4e-06	55.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria,4EKD4@85012|Streptosporangiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_966168_16	1048339.KB913029_gene2616	5.411e-40	159.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158347_k127_966168_4	42256.RradSPS_2674	3.844e-115	389.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_966168_28	525909.Afer_0097	8.096e-15	83.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158347_k127_966168_17	1211815.CBYP010000030_gene1283	2.279e-38	156.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4ETEP@85013|Frankiales	201174|Actinobacteria	E	prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158347_k127_966168_2	1032480.MLP_31880	1.579e-126	417.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,2GJDH@201174|Actinobacteria,4DN8I@85009|Propionibacteriales	201174|Actinobacteria	E	phosphoserine phosphatase	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
SRR25158347_k127_966168_31	1123023.JIAI01000013_gene3988	2.97e-07	58.0	COG1848@1|root,COG1848@2|Bacteria,2HDIZ@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_966168_25	485913.Krac_7590	7.056e-24	115.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_966168_30	1120950.KB892741_gene2695	3.467e-09	63.0	COG1920@1|root,COG1920@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158347_k127_966168_29	795666.MW7_3331	9.26e-14	79.0	COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,2VWWX@28216|Betaproteobacteria,1KAZ2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Guanylyl transferase CofC like	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158347_k127_966168_6	1380356.JNIK01000016_gene3791	4.63e-110	366.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4ERKS@85013|Frankiales	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158347_k127_966168_7	487521.OCU_49660	6.902e-100	337.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,236AX@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0018193,GO:0018205,GO:0019538,GO:0030312,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070490,GO:0070647,GO:0071704,GO:0071944,GO:1901564	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_966168_8	644966.Tmar_2181	5.705e-98	338.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158347_k127_966168_26	1123320.KB889676_gene2891	4.276e-23	106.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158347_k127_966168_24	649743.HMPREF0972_01299	1.388e-24	107.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D6AF@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158347_k127_966168_14	316274.Haur_4037	1.738e-49	190.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158347_k127_966168_11	2045.KR76_18390	8.207e-73	270.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4DPSS@85009|Propionibacteriales	201174|Actinobacteria	S	Dak1_2	dak3	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158347_k127_966168_1	1173264.KI913949_gene4394	2.188e-167	552.0	COG1200@1|root,COG1200@2|Bacteria,1G17H@1117|Cyanobacteria,1H8UT@1150|Oscillatoriales	1117|Cyanobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158347_k127_966168_0	33876.JNXY01000005_gene8733	2.018e-206	668.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4DAD5@85008|Micromonosporales	201174|Actinobacteria	E	Oligopeptidase b	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158347_k127_966168_20	1043493.BBLU01000018_gene1553	3.484e-36	156.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria	201174|Actinobacteria	L	methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158347_k127_966168_13	585531.HMPREF0063_11199	8.972e-61	213.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4DR12@85009|Propionibacteriales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158347_k127_966168_21	66897.DJ64_12960	2.046e-33	136.0	COG0711@1|root,COG0711@2|Bacteria,2GNBF@201174|Actinobacteria	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_966168_22	397278.JOJN01000001_gene2718	3.686e-31	128.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4DQUU@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158347_k127_966168_27	644283.Micau_1358	2.692e-15	77.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4DFJS@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158347_k127_966168_12	269800.Tfu_0651	3.717e-63	229.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4EGGX@85012|Streptosporangiales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158347_k127_966168_18	1229780.BN381_330022	2.515e-37	156.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158347_k127_966168_15	1211815.CBYP010000040_gene2547	7.74e-44	165.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4ERQY@85013|Frankiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158347_k127_969610_11	272569.rrnAC0082	5.159e-09	67.0	arCOG14225@1|root,arCOG14225@2157|Archaea,2XYCA@28890|Euryarchaeota,23W9H@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_969610_8	345341.KUTG_04140	2.815e-15	79.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_969610_1	1122933.JNIY01000004_gene2272	8.457e-123	411.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4F0SW@85016|Cellulomonadaceae	201174|Actinobacteria	G	PFAM glycosyl transferase family 20	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158347_k127_969610_7	266940.Krad_0919	1.096e-32	137.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158347_k127_969610_9	545264.KB898746_gene751	9.187e-15	86.0	COG2199@1|root,COG3221@1|root,COG2199@2|Bacteria,COG3221@2|Bacteria,1RGCV@1224|Proteobacteria,1T4CM@1236|Gammaproteobacteria,1X2R2@135613|Chromatiales	135613|Chromatiales	T	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_8,Phosphonate-bd
SRR25158347_k127_969610_10	471855.Shel_09960	6.164e-10	68.0	COG1579@1|root,COG1579@2|Bacteria,2HTFI@201174|Actinobacteria,4CVXI@84998|Coriobacteriia	84998|Coriobacteriia	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158347_k127_969610_4	555088.DealDRAFT_0015	9.828e-78	277.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,42JJ2@68298|Syntrophomonadaceae	186801|Clostridia	C	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158347_k127_969610_5	909613.UO65_2927	1.449e-66	239.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4E0AR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_969610_3	263358.VAB18032_22345	6.424e-81	284.0	COG0395@1|root,COG0395@2|Bacteria,2IPUK@201174|Actinobacteria,4DER9@85008|Micromonosporales	201174|Actinobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158347_k127_969610_0	263358.VAB18032_22350	2.906e-152	509.0	COG1653@1|root,COG1653@2|Bacteria,2GK9G@201174|Actinobacteria,4DAQN@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158347_k127_969610_2	263358.VAB18032_22360	9.454e-83	295.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4DDBX@85008|Micromonosporales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158347_k127_969610_6	1078020.KEK_06513	1.092e-36	148.0	COG2267@1|root,COG2267@2|Bacteria,2I3KS@201174|Actinobacteria,23FH2@1762|Mycobacteriaceae	201174|Actinobacteria	I	TAP-like protein	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158347_k127_98256_3	525909.Afer_1848	3.877e-49	188.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_98256_1	1146883.BLASA_0311	2.902e-86	299.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4ES7J@85013|Frankiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158347_k127_98256_6	913848.AELK01000168_gene1178	2.535e-39	162.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae	91061|Bacilli	S	AI-2E family transporter	yueF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158347_k127_98256_7	1303518.CCALI_00427	7.722e-33	135.0	COG0745@1|root,COG0745@2|Bacteria	1303518.CCALI_00427|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
SRR25158347_k127_98256_5	1192034.CAP_0985	1.63e-44	183.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2YUN4@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
SRR25158347_k127_98256_8	397278.JOJN01000006_gene1053	2.772e-32	130.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4DRWZ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158347_k127_98256_9	545243.BAEV01000078_gene3012	1.62e-08	64.0	COG1525@1|root,COG2333@1|root,COG1525@2|Bacteria,COG2333@2|Bacteria,1V8AM@1239|Firmicutes,25BE0@186801|Clostridia,36WHK@31979|Clostridiaceae	186801|Clostridia	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158347_k127_98256_0	479434.Sthe_0989	4.56e-119	407.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	189775|Thermomicrobia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158347_k127_98256_2	1078085.HMPREF1210_03404	8.28e-64	226.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,26CWY@186818|Planococcaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_98256_4	1184609.KILIM_027_00100	4.229e-45	168.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4F62A@85018|Dermatophilaceae	201174|Actinobacteria	J	RNA 2'-O ribose methyltransferase substrate binding	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158347_k127_996647_7	1123267.JONN01000001_gene1706	1.715e-62	226.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,2UKB8@28211|Alphaproteobacteria,2K99E@204457|Sphingomonadales	204457|Sphingomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158347_k127_996647_6	649638.Trad_0087	1.458e-62	225.0	COG0572@1|root,COG0572@2|Bacteria,1WMB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	-
SRR25158347_k127_996647_3	543632.JOJL01000014_gene9112	9.229e-98	333.0	COG4992@1|root,COG4992@2|Bacteria,2GIYG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158347_k127_996647_8	67275.JOAP01000037_gene3023	3.899e-58	218.0	2BWNB@1|root,32WFI@2|Bacteria,2IAXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_996647_17	1033810.HLPCO_000886	6.378e-11	74.0	2FJYI@1|root,34BKW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_996647_2	1121020.JIAG01000010_gene219	5.501e-111	372.0	2APJB@1|root,31ENF@2|Bacteria,2ICGD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_996647_0	479431.Namu_2609	1.422e-199	636.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4EUC0@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158347_k127_996647_1	479431.Namu_2608	9.342e-168	534.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158347_k127_996647_14	404589.Anae109_1049	4.428e-29	128.0	COG2867@1|root,COG2867@2|Bacteria,1RFKW@1224|Proteobacteria	1224|Proteobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_996647_5	211114.JOEF01000005_gene2105	3.098e-64	231.0	COG0753@1|root,COG0753@2|Bacteria,2GN9F@201174|Actinobacteria,4E32Z@85010|Pseudonocardiales	201174|Actinobacteria	P	Has an organic peroxide-dependent peroxidase activity	-	GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019222,GO:0020037,GO:0031323,GO:0042221,GO:0042743,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0065007,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748,GO:2000377	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
SRR25158347_k127_996647_10	1177594.MIC448_2190012	1.889e-43	177.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158347_k127_996647_11	404589.Anae109_2298	2.566e-43	180.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB4	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158347_k127_996647_4	290397.Adeh_1193	1.222e-88	323.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	cheAY40H-2	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
SRR25158347_k127_996647_9	502025.Hoch_3254	1.072e-57	224.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1MU9B@1224|Proteobacteria,42N1S@68525|delta/epsilon subdivisions,2WK7R@28221|Deltaproteobacteria,2YUUY@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	mcp40H-21	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,dCache_1
SRR25158347_k127_996647_22	1190606.AJYG01000171_gene72	0.0001991	51.0	COG0835@1|root,COG0835@2|Bacteria,1PH8Z@1224|Proteobacteria,1TJ8U@1236|Gammaproteobacteria,1Y0TU@135623|Vibrionales	135623|Vibrionales	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
SRR25158347_k127_996647_13	324602.Caur_0847	1.416e-37	158.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,2G79T@200795|Chloroflexi,3765U@32061|Chloroflexia	32061|Chloroflexia	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16
SRR25158347_k127_996647_19	298386.PBPRB0762	1.745e-05	55.0	COG0835@1|root,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XT9E@135623|Vibrionales	135623|Vibrionales	T	COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
SRR25158347_k127_996647_16	449447.MAE_12250	1.456e-25	122.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1FZVR@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_996647_23	671143.DAMO_1484	0.0004243	53.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
SRR25158347_k127_996647_18	469383.Cwoe_3431	1.522e-10	72.0	2AWXU@1|root,31NVG@2|Bacteria,2INAP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_996647_24	443255.SCLAV_1580	0.0007565	51.0	2CNM1@1|root,32SHB@2|Bacteria,2GKWT@201174|Actinobacteria	201174|Actinobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
SRR25158347_k127_996647_15	136273.GY22_01920	1.702e-26	123.0	2CNM1@1|root,32SHB@2|Bacteria,2GKWT@201174|Actinobacteria,1WAP6@1268|Micrococcaceae	201174|Actinobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
SRR25158347_k127_996647_21	1565129.JSFF01000015_gene67	0.0001728	51.0	2BH5I@1|root,32B6M@2|Bacteria,1RKHK@1224|Proteobacteria,1S7RV@1236|Gammaproteobacteria,2QCZP@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
## 3200 queries scanned
## Total time (seconds): 9.16767144203186
## Rate: 349.05 q/s