## Thu Feb 19 00:49:01 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158347_bin.46.fa -m mmseqs --output SRR25158347_bin.46 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158347_bin.46 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158347_k127_1004034_0	748449.Halha_0673	1.364e-97	335.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,3WABD@53433|Halanaerobiales	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
SRR25158347_k127_1004034_2	1293054.HSACCH_02293	1.236e-39	163.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,249R1@186801|Clostridia,3WAN1@53433|Halanaerobiales	186801|Clostridia	N	PFAM SRP54-type protein, GTPase domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
SRR25158347_k127_1004034_1	1307761.L21SP2_1202	7.505e-42	160.0	COG0455@1|root,COG0455@2|Bacteria,2J5B7@203691|Spirochaetes	203691|Spirochaetes	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
SRR25158347_k127_100675_0	1111454.HMPREF1250_1651	5.526e-110	372.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4H35U@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158347_k127_100675_2	400682.PAC_15710463	2.688e-39	165.0	COG0666@1|root,KOG0502@2759|Eukaryota,39UZK@33154|Opisthokonta	33154|Opisthokonta	S	Ankyrin repeats (3 copies)	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank,Ank_2,Ank_4,Ank_5,NACHT,PNP_UDP_1
SRR25158347_k127_100675_1	1341151.ASZU01000002_gene1657	1.282e-90	313.0	COG1716@1|root,COG1716@2|Bacteria,1TS4P@1239|Firmicutes,4HV5R@91061|Bacilli	91061|Bacilli	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158347_k127_1007504_0	485916.Dtox_4266	1.762e-51	198.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1TWCW@1239|Firmicutes,25A37@186801|Clostridia,26428@186807|Peptococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,dCache_1
SRR25158347_k127_1011252_0	179408.Osc7112_2565	2.011e-146	473.0	COG0515@1|root,COG0642@1|root,COG0784@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_1011872_0	1122985.HMPREF1991_01533	0.0005378	48.0	2C6KN@1|root,32Y69@2|Bacteria	2|Bacteria	S	VRR-NUC domain	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
SRR25158347_k127_1016826_0	1121448.DGI_1270	8.33e-59	224.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2M86M@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
SRR25158347_k127_1018062_0	1519464.HY22_11835	7.61e-26	111.0	COG0002@1|root,COG0002@2|Bacteria,1FDE1@1090|Chlorobi	1090|Chlorobi	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158347_k127_1018062_1	795359.TOPB45_0116	0.0001728	51.0	COG0775@1|root,COG0775@2|Bacteria,2GGXX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Phosphorylase superfamily	-	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158347_k127_1019696_0	290402.Cbei_2915	4.543e-27	114.0	COG4642@1|root,COG4642@2|Bacteria,1VK3V@1239|Firmicutes,25BBR@186801|Clostridia,36WCB@31979|Clostridiaceae	186801|Clostridia	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_1019696_2	1123277.KB893184_gene4141	5.622e-08	57.0	COG0501@1|root,COG4642@1|root,COG0501@2|Bacteria,COG4642@2|Bacteria,4NJPY@976|Bacteroidetes,47K9K@768503|Cytophagia	976|Bacteroidetes	O	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN,Peptidase_C14,Peptidase_M48
SRR25158347_k127_1019696_1	1319815.HMPREF0202_01644	7.885e-25	113.0	COG0500@1|root,COG2226@2|Bacteria,37CTJ@32066|Fusobacteria	32066|Fusobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_102011_1	102125.Xen7305DRAFT_00001960	1.117e-24	108.0	COG4642@1|root,COG4642@2|Bacteria,1G3W5@1117|Cyanobacteria,3VKVD@52604|Pleurocapsales	1117|Cyanobacteria	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN,Pentapeptide
SRR25158347_k127_102011_0	889378.Spiaf_1383	5.58e-32	131.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158347_k127_1023518_1	313628.LNTAR_01055	2.383e-25	108.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
SRR25158347_k127_1023518_0	244582.JQAK01000004_gene339	1.584e-54	199.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,47F9X@766|Rickettsiales	766|Rickettsiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158347_k127_1025264_0	574087.Acear_1622	2.609e-24	106.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,3WAMV@53433|Halanaerobiales	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
SRR25158347_k127_1026532_0	329726.AM1_0471	2.406e-63	230.0	COG0841@1|root,COG0841@2|Bacteria,1G21T@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_1026532_1	1385935.N836_02910	7.433e-24	106.0	COG2905@1|root,COG3829@1|root,COG5002@1|root,COG2905@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR25158347_k127_1029302_0	1267535.KB906767_gene3128	4.882e-51	190.0	COG0300@1|root,COG0300@2|Bacteria,3Y6RQ@57723|Acidobacteria,2JM94@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158347_k127_1031175_1	469618.FVAG_02743	8.272e-05	52.0	COG2849@1|root,COG2849@2|Bacteria,37C34@32066|Fusobacteria	2|Bacteria	S	MORN repeat variant	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	MORN,MORN_2
SRR25158347_k127_1031175_0	880070.Cycma_2882	3.834e-88	292.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,47N6N@768503|Cytophagia	976|Bacteroidetes	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
SRR25158347_k127_1038616_1	457412.RSAG_00919	1.56e-09	69.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158347_k127_1038616_0	1385514.N782_13570	2.6e-22	100.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,2Y9GS@289201|Pontibacillus	91061|Bacilli	C	Glycerophosphodiester phosphodiesterase	ugpQ_1	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158347_k127_104011_0	985255.APHJ01000023_gene2674	6.516e-61	217.0	COG0642@1|root,COG2202@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
SRR25158347_k127_1044263_3	1288826.MSNKSG1_01188	0.0001056	49.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158347_k127_1044263_2	889378.Spiaf_1213	2.328e-22	98.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158347_k127_1044263_1	1234409.C683_0804	2.607e-23	101.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,4B30K@81852|Enterococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158347_k127_1044263_0	1304885.AUEY01000037_gene2205	4.68e-54	197.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2MHRY@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158347_k127_1050300_0	1487921.DP68_10245	2.981e-38	153.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158347_k127_1050300_1	1319815.HMPREF0202_00359	3.049e-13	72.0	COG0774@1|root,COG0774@2|Bacteria,3794N@32066|Fusobacteria	32066|Fusobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
SRR25158347_k127_1050922_1	517418.Ctha_1928	2.468e-78	274.0	COG0591@1|root,COG0591@2|Bacteria,1FDKA@1090|Chlorobi	1090|Chlorobi	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158347_k127_1050922_0	1123368.AUIS01000004_gene205	1.455e-99	331.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,1RNZ8@1236|Gammaproteobacteria,2ND0C@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158347_k127_1051125_0	313606.M23134_02907	1.546e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158347_k127_1057556_0	1121472.AQWN01000001_gene269	7.989e-113	373.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,260QA@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158347_k127_1057556_1	243275.TDE_2073	3.499e-47	177.0	COG0457@1|root,COG0457@2|Bacteria,2J5I5@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SRR25158347_k127_1058578_0	1499967.BAYZ01000082_gene1015	1.286e-31	128.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_3,Response_reg,SpoIIE
SRR25158347_k127_1058578_1	2423.NA23_0209590	3.18e-11	75.0	COG1413@1|root,COG1413@2|Bacteria,2GDN4@200918|Thermotogae	200918|Thermotogae	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158347_k127_106172_0	1173029.JH980292_gene1978	2.452e-79	283.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158347_k127_106172_1	459495.SPLC1_S081740	7.685e-11	65.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_106245_1	1408473.JHXO01000010_gene3641	9.552e-52	198.0	COG0739@1|root,COG4413@1|root,COG0739@2|Bacteria,COG4413@2|Bacteria,4NJUQ@976|Bacteroidetes	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,UT
SRR25158347_k127_106245_0	648996.Theam_0938	1.482e-83	284.0	COG0019@1|root,COG0019@2|Bacteria,2G3VG@200783|Aquificae	200783|Aquificae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158347_k127_1067444_2	400668.Mmwyl1_0660	2.13e-07	53.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBT@135619|Oceanospirillales	135619|Oceanospirillales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158347_k127_1067444_0	1255043.TVNIR_0216	1.117e-57	216.0	COG0477@1|root,COG2814@2|Bacteria,1RCII@1224|Proteobacteria	1224|Proteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1067444_1	1123514.KB905901_gene149	4.881e-14	75.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZPF@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_1067781_0	665952.HMPREF1015_00568	4.094e-07	57.0	COG0517@1|root,COG0517@2|Bacteria,1V7SC@1239|Firmicutes,4HGJP@91061|Bacilli,1ZRPY@1386|Bacillus	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	acuB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158347_k127_1068283_0	326297.Sama_3507	5.691e-15	87.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,2Q9SF@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM sulfatase	Z012_06300	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_1079071_0	1237149.C900_04408	9.891e-289	898.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158347_k127_1080604_0	441769.ABFU01000060_gene495	1.288e-07	63.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9
SRR25158347_k127_1082656_0	1121904.ARBP01000005_gene4613	6.222e-47	175.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
SRR25158347_k127_1083643_0	760568.Desku_1657	3.552e-212	688.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158347_k127_1083643_1	485916.Dtox_2110	1.03e-15	80.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,260KV@186807|Peptococcaceae	186801|Clostridia	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158347_k127_1085778_0	517418.Ctha_1737	5.042e-95	338.0	COG1629@1|root,COG4771@2|Bacteria,1FEFM@1090|Chlorobi	1090|Chlorobi	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158347_k127_1090668_0	1380358.JADJ01000005_gene2704	4.08e-60	215.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158347_k127_1090668_1	1286171.EAL2_808p03780	4.102e-21	96.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_109321_0	1499967.BAYZ01000136_gene40	2.736e-93	317.0	COG4239@1|root,COG4239@2|Bacteria	2|Bacteria	P	microcin transport	yejE	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
SRR25158347_k127_109321_1	268407.PWYN_07405	4.435e-31	127.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26QZ3@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158347_k127_1095447_0	269799.Gmet_1290	8.806e-150	480.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158347_k127_1096536_0	1191523.MROS_1342	4.199e-153	487.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_1096536_1	720554.Clocl_3421	1.126e-151	488.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,3WI37@541000|Ruminococcaceae	186801|Clostridia	E	PFAM Cys Met metabolism	mccB	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158347_k127_1096536_2	237368.SCABRO_00104	1.474e-37	152.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	kinE	-	2.7.13.3	ko:K02491,ko:K13533,ko:K14986	ko02020,map02020	M00485,M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158347_k127_1097283_0	1123037.AUDE01000023_gene2769	1.17e-38	153.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_1097283_1	877420.ATVW01000005_gene827	1.412e-19	94.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia,27NAZ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_1101007_1	1123376.AUIU01000016_gene335	7.917e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,3J0MH@40117|Nitrospirae	40117|Nitrospirae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
SRR25158347_k127_1101007_0	483219.LILAB_17050	1.431e-54	196.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,42P1A@68525|delta/epsilon subdivisions,2WM73@28221|Deltaproteobacteria,2YWU1@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_1103120_0	1536769.P40081_30585	1.24e-67	237.0	COG1250@1|root,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,26TYA@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
SRR25158347_k127_1103120_1	457424.BFAG_04701	4.246e-37	145.0	COG0863@1|root,COG0863@2|Bacteria,4NK2X@976|Bacteroidetes,2FPTJ@200643|Bacteroidia,4ATPM@815|Bacteroidaceae	976|Bacteroidetes	H	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,SNase
SRR25158347_k127_1103637_0	1313301.AUGC01000004_gene2261	2.105e-21	101.0	COG0683@1|root,COG0683@2|Bacteria,4NIVQ@976|Bacteroidetes	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1105456_0	3075.A0A087SD08	8.173e-30	126.0	2B5H6@1|root,2S0J1@2759|Eukaryota,381MC@33090|Viridiplantae,34MX0@3041|Chlorophyta	3041|Chlorophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1107542_0	1385512.N784_05275	1.126e-16	83.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,4HA1Y@91061|Bacilli	91061|Bacilli	M	synthase	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR25158347_k127_1107542_1	997296.PB1_15259	6.06e-16	86.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158347_k127_1107542_2	357808.RoseRS_3045	3.294e-10	63.0	COG5573@1|root,COG5573@2|Bacteria	2|Bacteria	K	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_1108024_1	1144275.COCOR_07939	5.911e-87	293.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2YUI8@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158347_k127_1108024_0	889378.Spiaf_1256	3.971e-102	355.0	COG2114@1|root,COG2114@2|Bacteria,2J6HA@203691|Spirochaetes	203691|Spirochaetes	T	Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,Guanylate_cyc
SRR25158347_k127_1108265_0	1173029.JH980292_gene2872	2.675e-45	170.0	COG3344@1|root,COG3344@2|Bacteria,1G2NC@1117|Cyanobacteria,1HA8G@1150|Oscillatoriales	1117|Cyanobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
SRR25158347_k127_1108265_2	631362.Thi970DRAFT_04339	0.0004981	44.0	2DMHJ@1|root,32RM0@2|Bacteria,1NDZ0@1224|Proteobacteria,1SEPY@1236|Gammaproteobacteria,1WZRE@135613|Chromatiales	135613|Chromatiales	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158347_k127_1112357_0	1121396.KB892935_gene3831	8.877e-44	168.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WMEK@28221|Deltaproteobacteria,2MJC8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
SRR25158347_k127_1118622_0	1226325.HMPREF1548_03270	4.066e-43	162.0	COG1859@1|root,COG1859@2|Bacteria,1V49Y@1239|Firmicutes,24H56@186801|Clostridia,36E40@31979|Clostridiaceae	186801|Clostridia	H	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
SRR25158347_k127_111964_1	1313301.AUGC01000011_gene1165	3.758e-64	225.0	COG0463@1|root,COG0463@2|Bacteria,4NGJK@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254
SRR25158347_k127_111964_0	1123277.KB893239_gene1244	1.057e-67	243.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158347_k127_111964_2	335543.Sfum_2571	3.098e-43	159.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158347_k127_1121636_1	344747.PM8797T_00177	3.037e-26	119.0	2ESRG@1|root,33K9V@2|Bacteria,2J33K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1121636_0	349521.HCH_00144	2.014e-129	419.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XICM@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_1128549_0	1237149.C900_03713	7.112e-203	654.0	COG4206@1|root,COG4206@2|Bacteria,4P1R7@976|Bacteroidetes,47TPQ@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_1128681_0	1031288.AXAA01000022_gene1573	8.787e-94	316.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia,36FRH@31979|Clostridiaceae	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158347_k127_1128681_1	1230342.CTM_10858	4.461e-05	47.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,36GC9@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1134184_1	889378.Spiaf_2812	1.476e-05	48.0	COG0835@1|root,COG0835@2|Bacteria,2J8QZ@203691|Spirochaetes	203691|Spirochaetes	NT	chemotaxis protein	cheW-2	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158347_k127_1134184_0	795359.TOPB45_1469	2.241e-107	369.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,2GH2Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_1136227_0	869209.Tresu_1072	3.238e-33	147.0	COG0457@1|root,COG3391@1|root,COG0457@2|Bacteria,COG3391@2|Bacteria,2J5QG@203691|Spirochaetes	203691|Spirochaetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
SRR25158347_k127_1140335_3	742767.HMPREF9456_03412	8.374e-17	84.0	2EMSQ@1|root,33FF4@2|Bacteria,4P5SB@976|Bacteroidetes,2FV07@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF1064)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1064
SRR25158347_k127_1140335_0	1235790.C805_00032	6.718e-57	205.0	COG0270@1|root,COG0270@2|Bacteria,1VE3G@1239|Firmicutes,24NU5@186801|Clostridia,25YTI@186806|Eubacteriaceae	186801|Clostridia	L	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1140335_4	56107.Cylst_3532	3.291e-11	70.0	COG1403@1|root,COG1403@2|Bacteria,1G7VH@1117|Cyanobacteria,1HPC8@1161|Nostocales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_5
SRR25158347_k127_1140335_2	794903.OPIT5_19655	9.039e-24	106.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158347_k127_1140335_1	546275.FUSPEROL_02050	1.296e-32	132.0	COG0847@1|root,COG0847@2|Bacteria,37AH9@32066|Fusobacteria	32066|Fusobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
SRR25158347_k127_11431_1	246194.CHY_1459	1.067e-48	178.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,42GEH@68295|Thermoanaerobacterales	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158347_k127_11431_2	1122605.KB893643_gene865	1.021e-46	171.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158347_k127_11431_0	717231.Flexsi_1275	1.303e-51	193.0	COG0142@1|root,COG0142@2|Bacteria,2GEIX@200930|Deferribacteres	200930|Deferribacteres	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158347_k127_1143380_0	1189612.A33Q_0629	3.118e-64	234.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
SRR25158347_k127_1146292_0	297246.lpp0995	7.543e-76	265.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1JD2U@118969|Legionellales	118969|Legionellales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158347_k127_1146292_1	644107.SL1157_2038	2.01e-27	113.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,2UGR1@28211|Alphaproteobacteria,4NCST@97050|Ruegeria	28211|Alphaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158347_k127_1149086_0	56107.Cylst_2170	4.053e-113	389.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GKA7@1117|Cyanobacteria,1HQHZ@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_1149572_1	401053.AciPR4_1900	2.262e-29	125.0	COG0477@1|root,COG0477@2|Bacteria,3Y2V8@57723|Acidobacteria,2JI1F@204432|Acidobacteriia	204432|Acidobacteriia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1149572_0	1168034.FH5T_00605	6.081e-127	415.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,2FPUT@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_1149572_2	1408424.JHYI01000004_gene3597	2.708e-13	79.0	COG1051@1|root,COG1051@2|Bacteria,1V7VS@1239|Firmicutes,4HIKC@91061|Bacilli,1ZFKQ@1386|Bacillus	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_115051_1	211165.AJLN01000104_gene6547	9.215e-44	172.0	COG3437@1|root,COG3829@1|root,COG5002@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1JHAP@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
SRR25158347_k127_115051_0	926549.KI421517_gene3982	1.919e-103	352.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,47MZE@768503|Cytophagia	976|Bacteroidetes	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158347_k127_115051_2	1131269.AQVV01000003_gene754	4.286e-11	63.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_115065_0	316067.Geob_0837	8.524e-238	744.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158347_k127_1150731_0	79684.XP_005354158.1	7.589e-205	661.0	COG0145@1|root,KOG1939@2759|Eukaryota,38C8D@33154|Opisthokonta,3BHEN@33208|Metazoa,3CYN2@33213|Bilateria,4829K@7711|Chordata,48WWW@7742|Vertebrata,3JBUV@40674|Mammalia,35MD6@314146|Euarchontoglires,4PU6Q@9989|Rodentia	33208|Metazoa	E	5-oxoprolinase (ATP-hydrolyzing) activity	OPLAH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158347_k127_1150731_1	42099.EPrPV00000023612	1.831e-06	55.0	COG2039@1|root,KOG4755@2759|Eukaryota,1MHDW@121069|Pythiales	121069|Pythiales	O	Pyroglutamyl peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C15
SRR25158347_k127_1151861_1	1121447.JONL01000001_gene422	1.498e-29	120.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2MDG6@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158347_k127_1151861_2	1121447.JONL01000001_gene735	5.811e-12	68.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1151861_0	1121423.JONT01000003_gene979	1.339e-62	220.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158347_k127_1154305_2	111781.Lepto7376_4031	2.344e-76	261.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1H7FT@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Nucleos_tra2_C,Nucleos_tra2_N
SRR25158347_k127_1154305_0	639030.JHVA01000001_gene3282	2.43e-135	436.0	COG0074@1|root,COG0074@2|Bacteria,3Y3UX@57723|Acidobacteria,2JHSN@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158347_k127_1154305_1	880073.Calab_0629	1.476e-86	289.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158347_k127_1157420_2	759914.BP951000_1781	3.318e-96	322.0	COG0673@1|root,COG0673@2|Bacteria,2J6J2@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG0673 dehydrogenase and related protein	-	-	1.1.1.370	ko:K16043	ko00562,ko01120,map00562,map01120	-	R09953	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158347_k127_1157420_1	243231.GSU0034	4.387e-124	407.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43U2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158347_k127_1157420_0	573413.Spirs_3198	1.442e-264	829.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158347_k127_1157420_3	926569.ANT_25060	9.76e-17	88.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158347_k127_1157420_4	1121422.AUMW01000027_gene433	4.445e-11	66.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,260NG@186807|Peptococcaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158347_k127_1158612_1	929562.Emtol_1908	3.384e-34	139.0	COG3876@1|root,COG3876@2|Bacteria,4P1CP@976|Bacteroidetes,47U2C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158347_k127_1158612_0	1125863.JAFN01000001_gene564	1.177e-45	171.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158347_k127_1160651_0	1201288.M900_1005	2.212e-12	71.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,42Y3Q@68525|delta/epsilon subdivisions,2MTU8@213481|Bdellovibrionales,2WT53@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
SRR25158347_k127_1164210_0	865937.Gilli_2868	7.332e-47	173.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,4NQQR@976|Bacteroidetes,1I35C@117743|Flavobacteriia,2P7DB@244698|Gillisia	976|Bacteroidetes	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
SRR25158347_k127_1165308_2	1110502.TMO_2501	3.926e-05	48.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,1MVN2@1224|Proteobacteria,2TUT9@28211|Alphaproteobacteria,2JQH6@204441|Rhodospirillales	204441|Rhodospirillales	HJK	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,RimK
SRR25158347_k127_1165308_0	572477.Alvin_1618	9.8e-150	481.0	COG1363@1|root,COG1363@2|Bacteria,1MXEU@1224|Proteobacteria,1RSHP@1236|Gammaproteobacteria,1WWZP@135613|Chromatiales	135613|Chromatiales	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158347_k127_1165308_1	1168067.JAGP01000001_gene86	1.202e-83	286.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type phosphate phosphonate transport system periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158347_k127_1166883_0	1304885.AUEY01000001_gene3285	4.623e-78	271.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,2MITG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	4-hydroxybenzoate polyprenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158347_k127_1166883_1	82654.Pse7367_1288	7.763e-45	169.0	COG0163@1|root,COG0163@2|Bacteria,1G1FS@1117|Cyanobacteria,1H7VQ@1150|Oscillatoriales	1117|Cyanobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158347_k127_1167422_1	1289135.A966_06335	1.513e-09	70.0	COG1366@1|root,COG1366@2|Bacteria,2J7R1@203691|Spirochaetes	203691|Spirochaetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_1167422_0	313612.L8106_01082	2.491e-32	141.0	COG2304@1|root,COG2304@2|Bacteria,1G1BE@1117|Cyanobacteria,1H7KW@1150|Oscillatoriales	1117|Cyanobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SRR25158347_k127_1168201_0	159087.Daro_4059	6.095e-143	463.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria,2VZKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SRR25158347_k127_1169412_0	889378.Spiaf_0731	1.141e-32	136.0	COG0642@1|root,COG3221@1|root,COG5002@1|root,COG0642@2|Bacteria,COG3221@2|Bacteria,COG5002@2|Bacteria,2J58F@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,Hemerythrin,HisKA,PAS_4,Response_reg,dCache_1
SRR25158347_k127_1170325_2	742727.HMPREF9447_02002	1.494e-12	70.0	COG1373@1|root,COG1373@2|Bacteria,4NG8U@976|Bacteroidetes,2FP3K@200643|Bacteroidia,4AM7Q@815|Bacteroidaceae	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158347_k127_1170325_1	1295642.H839_15032	2.36e-25	107.0	2DNMU@1|root,32Y5V@2|Bacteria,1VN9X@1239|Firmicutes,4HXCG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1170325_0	655815.ZPR_1936	7.691e-56	201.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1HY18@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_117080_1	933262.AXAM01000023_gene655	4.188e-27	111.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,42S4I@68525|delta/epsilon subdivisions,2WNXV@28221|Deltaproteobacteria,2MNF8@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG3	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_117080_2	292459.STH410	7.425e-09	61.0	COG0640@1|root,COG0640@2|Bacteria,1VPBF@1239|Firmicutes,24VJN@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158347_k127_117080_0	743722.Sph21_2200	4.169e-109	363.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
SRR25158347_k127_1174235_0	1201290.M902_0650	7.203e-11	70.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,43C9X@68525|delta/epsilon subdivisions,2MTUK@213481|Bdellovibrionales,2X7KD@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1179272_0	1245471.PCA10_16790	6.114e-24	118.0	COG3210@1|root,COG3210@2|Bacteria,1QUUN@1224|Proteobacteria	1224|Proteobacteria	U	Outer membrane autotransporter	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	Big_3_3,ESPR,PATR
SRR25158347_k127_1183219_0	313590.MED134_13381	2.729e-62	235.0	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,4NDXU@976|Bacteroidetes,1HZV8@117743|Flavobacteriia,37EY2@326319|Dokdonia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_1186161_1	1145276.T479_03280	3.402e-25	119.0	COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,4HG5W@91061|Bacilli,3J061@400634|Lysinibacillus	91061|Bacilli	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
SRR25158347_k127_1186161_0	573413.Spirs_2933	4.129e-35	142.0	COG0535@1|root,COG0535@2|Bacteria,2J6HP@203691|Spirochaetes	203691|Spirochaetes	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158347_k127_1186876_0	472759.Nhal_1891	1.07e-93	324.0	COG0784@1|root,COG1352@1|root,COG2201@1|root,COG2433@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2433@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SRR25158347_k127_1202023_1	671143.DAMO_1620	1.533e-48	175.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158347_k127_1202023_0	1191523.MROS_1977	1.634e-243	767.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158347_k127_1204369_0	517418.Ctha_0809	1.247e-71	251.0	COG0507@1|root,COG0507@2|Bacteria,1FENM@1090|Chlorobi	1090|Chlorobi	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	PIF1
SRR25158347_k127_1204369_1	443254.Marpi_1406	1.531e-28	121.0	COG0817@1|root,COG0817@2|Bacteria,2GD6C@200918|Thermotogae	200918|Thermotogae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158347_k127_1204525_0	945713.IALB_0948	0.0	1266.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158347_k127_1206583_0	1047013.AQSP01000123_gene1546	1.311e-11	72.0	COG4953@1|root,COG4953@2|Bacteria,2NQMA@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
SRR25158347_k127_1206583_1	448385.sce6347	6.541e-09	62.0	COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,42R90@68525|delta/epsilon subdivisions,2WMUJ@28221|Deltaproteobacteria,2YWD8@29|Myxococcales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158347_k127_120894_1	641147.HMPREF9021_01911	1.723e-35	138.0	28JM7@1|root,2Z9DS@2|Bacteria,1R8QS@1224|Proteobacteria,2VYJA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_120894_4	97139.C824_05923	2.641e-06	51.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,36GXG@31979|Clostridiaceae	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SRR25158347_k127_120894_3	926692.AZYG01000096_gene1904	2.917e-19	93.0	COG5464@1|root,COG5464@2|Bacteria,1V8QY@1239|Firmicutes,25D0U@186801|Clostridia	186801|Clostridia	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SRR25158347_k127_120894_5	35841.BT1A1_2477	0.0005206	47.0	COG5464@1|root,COG5464@2|Bacteria,1TWKK@1239|Firmicutes	1239|Firmicutes	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SRR25158347_k127_120894_2	7739.XP_002612454.1	4.739e-23	108.0	2CY5X@1|root,2S297@2759|Eukaryota,3A4B3@33154|Opisthokonta,3BRRW@33208|Metazoa,3D997@33213|Bilateria	33208|Metazoa	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_120894_0	313606.M23134_06670	1.109e-85	306.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
SRR25158347_k127_1209301_3	1416760.AYMS01000075_gene2964	7.642e-19	90.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia,47I1F@76831|Myroides	976|Bacteroidetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_1209301_0	247490.KSU1_D0316	2.667e-167	542.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158347_k127_1209301_2	880072.Desac_2104	4.89e-82	290.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2MSIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158347_k127_1209301_1	1124780.ANNU01000010_gene3652	3.009e-120	397.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,47NX6@768503|Cytophagia	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
SRR25158347_k127_1210033_0	221288.JH992901_gene4060	3.22e-242	775.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,1JHAR@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_1210777_0	314285.KT71_06202	5.232e-57	209.0	COG2271@1|root,COG2271@2|Bacteria,1MXUC@1224|Proteobacteria,1RRF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1211609_1	869213.JCM21142_3860	2.199e-105	345.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
SRR25158347_k127_1211609_0	1270196.JCKI01000002_gene637	4.79e-141	452.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1INWY@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158347_k127_1211609_2	762903.Pedsa_0238	2.642e-32	126.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1IQ9Q@117747|Sphingobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158347_k127_1212049_2	5762.XP_002682575.1	1.739e-08	64.0	2E5JK@1|root,2SCCU@2759|Eukaryota	2759|Eukaryota	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K19619	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158347_k127_1212049_0	91464.S7335_4950	3.303e-34	147.0	COG0204@1|root,COG0204@2|Bacteria,1G3F1@1117|Cyanobacteria,1H47Q@1129|Synechococcus	1117|Cyanobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158347_k127_1212049_1	1196323.ALKF01000203_gene3744	5.762e-15	75.0	COG2329@1|root,COG2329@2|Bacteria,1VCZF@1239|Firmicutes,4HMH1@91061|Bacilli,26YFG@186822|Paenibacillaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	yczJ	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158347_k127_121295_0	697282.Mettu_1544	6.95e-08	64.0	COG1629@1|root,COG4771@2|Bacteria,1PGNC@1224|Proteobacteria,1RX1N@1236|Gammaproteobacteria,1XG7S@135618|Methylococcales	135618|Methylococcales	P	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
SRR25158347_k127_1213670_0	765869.BDW_12765	4.143e-106	362.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2MSZP@213481|Bdellovibrionales,2WJ5V@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158347_k127_1213670_1	768710.DesyoDRAFT_1807	4.785e-13	76.0	28MIG@1|root,2ZAV8@2|Bacteria,1V2VJ@1239|Firmicutes,24G9N@186801|Clostridia	186801|Clostridia	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
SRR25158347_k127_1214445_2	1250278.JQNQ01000001_gene3605	6.347e-34	133.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1I2TQ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158347_k127_1214445_0	387092.NIS_0988	5.736e-50	181.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2YPDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GatB Yqey family protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158347_k127_1214445_1	1395571.TMS3_0109665	5.1e-49	180.0	COG3631@1|root,COG3631@2|Bacteria,1MZ0P@1224|Proteobacteria,1S7Z4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ketosteroid	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158347_k127_1214445_3	4565.Traes_2BL_4E6E2CBE2.1	1.779e-07	59.0	28M86@1|root,2QTRC@2759|Eukaryota,37KR5@33090|Viridiplantae,3GCHQ@35493|Streptophyta,3KXWM@4447|Liliopsida,3IA0M@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF150
SRR25158347_k127_1214596_2	1203606.HMPREF1526_02792	7.165e-06	57.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia,36DF3@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
SRR25158347_k127_1214596_0	243365.CV_2963	7.858e-54	196.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KPQ6@206351|Neisseriales	206351|Neisseriales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158347_k127_1219628_0	448385.sce8244	8.383e-05	51.0	COG2453@1|root,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,43A8J@68525|delta/epsilon subdivisions,2X3DG@28221|Deltaproteobacteria,2YVJ1@29|Myxococcales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
SRR25158347_k127_1222793_1	1173029.JH980292_gene1838	5.311e-08	56.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,dCache_1
SRR25158347_k127_1222793_0	880073.Calab_2310	1.118e-19	100.0	COG0726@1|root,COG0726@2|Bacteria,2NQ5B@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158347_k127_12359_1	314230.DSM3645_04470	3.566e-11	72.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158347_k127_12359_0	756272.Plabr_2566	1.527e-144	467.0	COG0004@1|root,COG0004@2|Bacteria,2IXR9@203682|Planctomycetes	203682|Planctomycetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158347_k127_1237027_0	862908.BMS_0458	1.145e-12	79.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158347_k127_1244660_1	358681.BBR47_57530	2.358e-60	214.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158347_k127_1244660_0	1480694.DC28_09930	1.668e-77	278.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_124780_2	665571.STHERM_c09170	3.305e-15	82.0	COG1843@1|root,COG1843@2|Bacteria,2J806@203691|Spirochaetes	203691|Spirochaetes	N	flagellar hook	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
SRR25158347_k127_124780_0	1123274.KB899413_gene847	3.328e-137	451.0	COG1749@1|root,COG1749@2|Bacteria,2J5H4@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar hook protein flgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_124780_1	204669.Acid345_4432	3.134e-90	317.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
SRR25158347_k127_1249157_1	653733.Selin_2361	1.959e-40	154.0	COG0439@1|root,COG0511@1|root,COG0439@2|Bacteria,COG0511@2|Bacteria	2|Bacteria	I	ligase activity, forming carbon-carbon bonds	accB	-	2.3.1.12,2.3.1.39,4.1.1.3,6.3.4.14,6.4.1.2	ko:K00627,ko:K00645,ko:K01572,ko:K01961,ko:K02160	ko00010,ko00020,ko00061,ko00333,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00333,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R01626,R02569,R04385,R11671	RC00004,RC00039,RC00040,RC00253,RC00367,RC02727,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01004,ko02000	3.B.1.1.1	-	-	Acyl_transf_1,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158347_k127_1249157_0	1283300.ATXB01000001_gene2452	9.395e-61	213.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,1S1VI@1236|Gammaproteobacteria,1XESX@135618|Methylococcales	135618|Methylococcales	Q	PFAM Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158347_k127_1249195_0	1094466.KQS_07560	1.471e-16	91.0	29U29@1|root,30FBH@2|Bacteria,4NPTB@976|Bacteroidetes,1INCC@117743|Flavobacteriia,2NZ1Q@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1255594_1	1487923.DP73_13055	4.516e-05	53.0	COG3243@1|root,COG3243@2|Bacteria,1V0SA@1239|Firmicutes,24D2G@186801|Clostridia	186801|Clostridia	I	poly(R)-hydroxyalkanoic acid synthase	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158347_k127_1255594_0	1121931.AUHG01000017_gene1596	1.446e-82	278.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,1I213@117743|Flavobacteriia	976|Bacteroidetes	S	Bacteriocin-protection protein	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158347_k127_1255790_2	297246.lpp2870	3.622e-07	52.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1JC4P@118969|Legionellales	118969|Legionellales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	yrfI	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRR25158347_k127_1255790_1	1392490.JHZX01000001_gene2834	3.779e-22	100.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1I3XP@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158347_k127_1255790_0	177439.DP0291	8.82e-43	162.0	COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,42P2N@68525|delta/epsilon subdivisions,2WM4M@28221|Deltaproteobacteria,2MJF1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease I	-	-	3.1.21.1	ko:K01150	-	-	-	-	ko00000,ko01000	-	-	-	Endonuclease_1
SRR25158347_k127_1256351_0	1250005.PHEL85_3012	2.263e-32	141.0	COG1345@1|root,COG2356@1|root,COG2374@1|root,COG3405@1|root,COG3420@1|root,COG3897@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG2374@2|Bacteria,COG3405@2|Bacteria,COG3420@2|Bacteria,COG3897@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	PA14
SRR25158347_k127_1258783_0	3067.XP_002954421.1	5.898e-35	139.0	COG0661@1|root,KOG1235@2759|Eukaryota,37IRM@33090|Viridiplantae,34H8A@3041|Chlorophyta	3041|Chlorophyta	S	ABC1 family	-	-	-	ko:K08869	-	-	-	-	ko00000,ko01001	-	-	-	ABC1
SRR25158347_k127_1258783_1	1121396.KB893107_gene1852	4.548e-07	53.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions,2WSC3@28221|Deltaproteobacteria,2MN4H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
SRR25158347_k127_1262852_1	367737.Abu_2333	3.762e-16	84.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,42W98@68525|delta/epsilon subdivisions,2YQFB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1262852_0	765869.BDW_08650	2.133e-122	410.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions,2WUEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_1269076_0	402777.KB235903_gene1652	3.642e-80	285.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_1273248_0	565034.BHWA1_01476	1.02e-33	141.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158347_k127_1275768_1	929713.NIASO_13345	1.22e-12	69.0	COG1396@1|root,COG1396@2|Bacteria,4NMVC@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158347_k127_1275768_0	379066.GAU_0927	1.41e-18	93.0	COG2353@1|root,COG2353@2|Bacteria,1ZUD3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158347_k127_1280198_2	1304875.JAFZ01000001_gene1886	0.0001091	49.0	COG1154@1|root,COG1154@2|Bacteria,3T9RX@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158347_k127_1280198_0	289376.THEYE_A0567	2.933e-120	397.0	COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_1280198_1	1313172.YM304_26900	1.541e-88	298.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158347_k127_1280720_0	314345.SPV1_00802	6.732e-16	80.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
SRR25158347_k127_1281875_0	1195236.CTER_4522	6.099e-89	297.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
SRR25158347_k127_1282693_0	397290.C810_00815	1.321e-23	113.0	COG1119@1|root,COG1119@2|Bacteria,1TQMJ@1239|Firmicutes,249V8@186801|Clostridia,27NEU@186928|unclassified Lachnospiraceae	186801|Clostridia	P	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1287078_0	1519464.HY22_01980	4.656e-53	201.0	COG4974@1|root,COG4974@2|Bacteria,1FF1Y@1090|Chlorobi	1090|Chlorobi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158347_k127_128777_1	5722.XP_001320431.1	1.115e-06	56.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
SRR25158347_k127_128777_2	573413.Spirs_2307	0.0001466	52.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	yrvJ	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448,ko:K05772,ko:K06385	ko01503,ko02010,map01503,map02010	M00186,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02000,ko03036	3.A.1.6.2,3.A.1.6.4	-	-	AMIN,Amidase_3,SH3_3,SLH
SRR25158347_k127_128777_0	880071.Fleli_2736	1.682e-65	226.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47MBG@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158347_k127_1288619_2	443144.GM21_1759	2.74e-21	94.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
SRR25158347_k127_1288619_1	335543.Sfum_1126	7.584e-30	124.0	COG2050@1|root,COG2050@2|Bacteria,1PPMI@1224|Proteobacteria,437C5@68525|delta/epsilon subdivisions,2X383@28221|Deltaproteobacteria,2MSCH@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_1288619_0	926562.Oweho_2008	1.149e-121	398.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia,2PADC@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhodanase C-terminal	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
SRR25158347_k127_1296243_0	1121904.ARBP01000006_gene3928	4.167e-77	264.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,47Q4V@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158347_k127_1296243_1	264462.Bd0284	0.0009153	44.0	COG2010@1|root,COG2010@2|Bacteria,1PXD4@1224|Proteobacteria,43159@68525|delta/epsilon subdivisions,2MU19@213481|Bdellovibrionales,2WWT0@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158347_k127_1299416_0	1173028.ANKO01000127_gene4122	3.062e-75	267.0	COG0515@1|root,COG0642@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,1GHS3@1117|Cyanobacteria,1HF2M@1150|Oscillatoriales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase
SRR25158347_k127_1301192_2	509635.N824_09395	7.907e-23	109.0	COG1024@1|root,COG1024@2|Bacteria,4NK1J@976|Bacteroidetes,1IQGA@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17,5.3.3.8	ko:K01692,ko:K13238	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R04756,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_1301192_0	402777.KB235903_gene1652	2.864e-82	293.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_1301192_1	398512.JQKC01000018_gene2915	2.051e-30	137.0	COG3287@1|root,COG3287@2|Bacteria,1UUKK@1239|Firmicutes,258KY@186801|Clostridia,3WQYZ@541000|Ruminococcaceae	186801|Clostridia	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158347_k127_1304159_2	1302858.I871_00805	2.503e-15	89.0	COG1345@1|root,COG1345@2|Bacteria,2J6CW@203691|Spirochaetes	203691|Spirochaetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliD_C,FliD_N
SRR25158347_k127_1304159_0	649747.HMPREF0083_00362	1.185e-188	613.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,26SKK@186822|Paenibacillaceae	91061|Bacilli	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158347_k127_1304159_1	1408473.JHXO01000002_gene3863	1.27e-15	89.0	COG3250@1|root,COG3250@2|Bacteria,4NN59@976|Bacteroidetes,2FQES@200643|Bacteroidia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom4_5
SRR25158347_k127_130482_0	1089552.KI911559_gene1193	4.778e-120	396.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2JPK2@204441|Rhodospirillales	204441|Rhodospirillales	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158347_k127_1309154_0	869213.JCM21142_3838	1.109e-70	256.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TK7@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_1310340_1	497964.CfE428DRAFT_1305	3.749e-05	48.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART PUR-alpha beta gamma DNA RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	PurA
SRR25158347_k127_1310340_0	744872.Spica_1692	1.007e-19	98.0	2EY48@1|root,33RD4@2|Bacteria,2J65N@203691|Spirochaetes	203691|Spirochaetes	N	flagellar filament outer layer protein	-	-	-	-	-	-	-	-	-	-	-	-	FlaA
SRR25158347_k127_1311073_0	313606.M23134_07479	4.984e-177	570.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
SRR25158347_k127_1313661_1	1033740.CAEW01000011_gene2185	7.607e-17	81.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,26DJK@186818|Planococcaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10965	ATP-synt_ab,ATP-synt_ab_N
SRR25158347_k127_1313661_0	1379270.AUXF01000004_gene3173	6.091e-65	232.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158347_k127_1313661_2	1307759.JOMJ01000003_gene2167	1.528e-10	64.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2M8U7@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158347_k127_1317020_1	889378.Spiaf_0472	2.824e-08	62.0	COG4254@1|root,COG4254@2|Bacteria,2J6MW@203691|Spirochaetes	203691|Spirochaetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158347_k127_1317020_0	1458275.AZ34_11415	1.013e-67	235.0	COG1196@1|root,COG2114@1|root,COG2770@1|root,COG1196@2|Bacteria,COG2114@2|Bacteria,COG2770@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158347_k127_1317817_0	215803.DB30_6384	2.304e-36	158.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SRR25158347_k127_1319494_0	470.IX87_11140	6.778e-78	265.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,3NJER@468|Moraxellaceae	1236|Gammaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_1319494_1	388467.A19Y_2320	6.119e-39	148.0	COG1085@1|root,COG1085@2|Bacteria,1G1CA@1117|Cyanobacteria,1H82Z@1150|Oscillatoriales	1117|Cyanobacteria	C	galactose-1-phosphate	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf,HIT
SRR25158347_k127_1323398_0	395493.BegalDRAFT_1813	1.714e-133	441.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,460E6@72273|Thiotrichales	72273|Thiotrichales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_1323398_1	641524.ADICYQ_1891	4.085e-26	110.0	2DN7D@1|root,32VY2@2|Bacteria,4NTEH@976|Bacteroidetes,47SUK@768503|Cytophagia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158347_k127_1325675_0	933262.AXAM01000028_gene3318	9.857e-174	556.0	COG1672@1|root,COG1672@2|Bacteria,1N4VD@1224|Proteobacteria,42Y71@68525|delta/epsilon subdivisions,2WTK1@28221|Deltaproteobacteria,2MMHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like
SRR25158347_k127_1325675_1	667014.Thein_0256	3.182e-09	58.0	COG1672@1|root,COG1672@2|Bacteria,2GHSB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	SPTR Conserved protein, with A weak D-galactarate dehydratase altronate hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
SRR25158347_k127_1325727_0	933262.AXAM01000009_gene1461	3.561e-146	472.0	COG1672@1|root,COG1672@2|Bacteria,1N4VD@1224|Proteobacteria,42Y71@68525|delta/epsilon subdivisions,2WTK1@28221|Deltaproteobacteria,2MMHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
SRR25158347_k127_1327322_0	1168034.FH5T_20815	4.422e-57	213.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,4PN7F@976|Bacteroidetes,2G14N@200643|Bacteroidia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_1327322_1	177439.DP2309	2.236e-31	136.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,43BUW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS,PAS_3,PAS_9,dCache_1
SRR25158347_k127_1329147_1	866546.EPY50387	7.862e-32	126.0	COG0492@1|root,KOG0404@2759|Eukaryota,38I0K@33154|Opisthokonta,3NW0C@4751|Fungi,3QKA3@4890|Ascomycota,3MC02@451866|Taphrinomycotina	4751|Fungi	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	TRR1	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0009636,GO:0009987,GO:0010035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019430,GO:0019725,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.6.5.5,1.8.1.9	ko:K00344,ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_1329147_0	386415.NT01CX_1554	3.669e-87	300.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,36DV2@31979|Clostridiaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_1330104_1	266835.14023104	0.0002773	49.0	28HDQ@1|root,2Z7Q9@2|Bacteria,1R41M@1224|Proteobacteria,2TTYR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1330104_0	1538644.KO02_23185	9.692e-45	168.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1IS7C@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158347_k127_1333129_0	998674.ATTE01000001_gene3834	6.292e-85	287.0	COG1373@1|root,COG1373@2|Bacteria,1R9U4@1224|Proteobacteria,1SK7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
SRR25158347_k127_1333129_1	391295.SSU05_1226	1.996e-13	74.0	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1WTUH@1307|Streptococcus suis	91061|Bacilli	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158347_k127_1334439_0	247490.KSU1_D0783	8.424e-61	220.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158347_k127_13384_1	330214.NIDE0040	3.501e-10	66.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SRR25158347_k127_13384_0	1121015.N789_04795	1.737e-40	162.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T2IJ@1236|Gammaproteobacteria,1X7CT@135614|Xanthomonadales	135614|Xanthomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_4
SRR25158347_k127_1338422_0	298386.PBPRC0025	3.568e-26	118.0	COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,1XVNE@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF1738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738
SRR25158347_k127_1340034_1	179408.Osc7112_3045	1.782e-38	151.0	COG4636@1|root,COG4636@2|Bacteria,1G5GI@1117|Cyanobacteria,1HB0Z@1150|Oscillatoriales	1117|Cyanobacteria	S	InterPro IPR008538	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158347_k127_1340034_0	1174528.JH992898_gene1877	1.314e-57	208.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1JH5Z@1189|Stigonemataceae	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158347_k127_1341326_1	1121895.Q765_01970	1.343e-113	369.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,1INE4@117743|Flavobacteriia,2NZ97@237|Flavobacterium	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158347_k127_1341326_2	395493.BegalDRAFT_0302	4.749e-39	154.0	COG2148@1|root,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3,STAS
SRR25158347_k127_1341326_0	755732.Fluta_1834	1.124e-248	779.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1HXS7@117743|Flavobacteriia,2PA8M@246874|Cryomorphaceae	976|Bacteroidetes	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
SRR25158347_k127_1342397_0	243231.GSU1140	4.911e-83	293.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,43STW@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp34H-3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,dCache_1
SRR25158347_k127_1342397_1	1499967.BAYZ01000074_gene2116	1.862e-17	89.0	COG0643@1|root,COG0643@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158347_k127_134337_1	1282362.AEAC466_17555	3.573e-26	112.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2U2BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158347_k127_134337_0	1282362.AEAC466_17560	9.279e-44	166.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158347_k127_134337_2	1150600.ADIARSV_4134	1.886e-16	90.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1IS1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
SRR25158347_k127_1343935_0	927658.AJUM01000046_gene14	2.792e-13	72.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FX61@200643|Bacteroidia,3XKI8@558415|Marinilabiliaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
SRR25158347_k127_1343935_2	580327.Tthe_1107	5.419e-05	53.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,42G3P@68295|Thermoanaerobacterales	186801|Clostridia	MT	SH3, type 3 domain protein	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	NLPC_P60,SH3_3
SRR25158347_k127_1344784_0	314607.KB13_1180	1.083e-43	167.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_16,TPR_8
SRR25158347_k127_1344784_1	1379698.RBG1_1C00001G1318	1.388e-08	64.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158347_k127_1354354_1	1521187.JPIM01000011_gene2627	3.343e-34	135.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_1354354_0	1128427.KB904821_gene3254	1.102e-34	150.0	COG5316@1|root,COG5316@2|Bacteria,1G2S6@1117|Cyanobacteria,1HA82@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SRR25158347_k127_1354510_0	313606.M23134_05475	2.439e-233	735.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
SRR25158347_k127_1354546_0	565034.BHWA1_00275	2.509e-30	132.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2J6I1@203691|Spirochaetes	203691|Spirochaetes	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
SRR25158347_k127_1354546_1	449447.MAE_01800	8.364e-08	62.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2
SRR25158347_k127_1355725_0	1094715.CM001373_gene461	3.028e-21	102.0	COG0745@1|root,COG4251@1|root,COG5002@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T3NV@1236|Gammaproteobacteria,1JDKY@118969|Legionellales	118969|Legionellales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158347_k127_1357260_1	196490.AUEZ01000015_gene4502	6.805e-69	244.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_1357260_0	1173027.Mic7113_5256	3.228e-96	322.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158347_k127_1357260_2	56780.SYN_02652	1.912e-21	97.0	COG0451@1|root,COG0451@2|Bacteria,1RBIE@1224|Proteobacteria,42QDU@68525|delta/epsilon subdivisions,2WJD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NAD-dependent epimerase dehydratase	-	-	1.1.1.339	ko:K19180	ko00523,ko01130,map00523,map01130	-	R10190	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158347_k127_1357449_0	338966.Ppro_0642	8.579e-272	848.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158347_k127_1358103_0	1205910.B005_1386	2.815e-31	126.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4EG6R@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158347_k127_1358103_1	1124780.ANNU01000044_gene513	0.0001306	55.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
SRR25158347_k127_1362129_0	1379281.AVAG01000014_gene1445	7.496e-112	383.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2M8F9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_1362558_1	1122134.KB893651_gene2051	1.234e-06	53.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,1S5J1@1236|Gammaproteobacteria,1XJWS@135619|Oceanospirillales	135619|Oceanospirillales	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158347_k127_1362558_0	1480694.DC28_14880	1.62e-107	361.0	COG0664@1|root,COG0664@2|Bacteria,2J5G6@203691|Spirochaetes	203691|Spirochaetes	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158347_k127_1362558_2	1230343.CANP01000042_gene3152	0.0007289	49.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1JCZY@118969|Legionellales	118969|Legionellales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SRR25158347_k127_1364166_1	266265.Bxe_B2483	2.451e-20	103.0	COG2374@1|root,COG4932@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,1R85W@1224|Proteobacteria,2VWBV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
SRR25158347_k127_1364166_0	1121346.KB899823_gene2331	2.822e-31	134.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,26SZV@186822|Paenibacillaceae	91061|Bacilli	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158347_k127_1364355_0	1121373.KB903621_gene1894	9.933e-41	166.0	COG0210@1|root,COG0210@2|Bacteria,4NJNQ@976|Bacteroidetes,47NVY@768503|Cytophagia	976|Bacteroidetes	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C
SRR25158347_k127_1364355_1	1196322.A370_02058	2.231e-31	125.0	COG0270@1|root,COG0270@2|Bacteria	2|Bacteria	L	DNA (cytosine-5-)-methyltransferase activity	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,Eco57I
SRR25158347_k127_1367577_0	383372.Rcas_3864	2.027e-69	252.0	COG5316@1|root,COG5316@2|Bacteria,2GBUR@200795|Chloroflexi,375C5@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_136956_0	1336233.JAEH01000007_gene2423	1.495e-23	109.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,2QBT3@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM NUDIX hydrolase	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818	-	-	-	-	-	-	-	-	-	-	DUF1289,NUDIX
SRR25158347_k127_136956_1	1267534.KB906755_gene4020	8.357e-14	79.0	COG2050@1|root,COG2050@2|Bacteria,3Y57I@57723|Acidobacteria,2JJU4@204432|Acidobacteriia	204432|Acidobacteriia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_1372044_0	1217658.F987_02155	0.0001911	49.0	2BH8J@1|root,32B9X@2|Bacteria,1PXZB@1224|Proteobacteria,1TMNN@1236|Gammaproteobacteria,3NP1I@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NinB
SRR25158347_k127_137301_1	1262449.CP6013_2023	2.319e-05	56.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,36UJN@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_137301_0	1173264.KI913949_gene647	3.229e-18	85.0	COG2343@1|root,COG2343@2|Bacteria,1G7U6@1117|Cyanobacteria,1HC91@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG2343 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158347_k127_1374362_1	1454004.AW11_01667	9.504e-43	161.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria	1224|Proteobacteria	I	Dehydratase	MA20_00775	-	4.2.1.148,4.2.1.56	ko:K14449,ko:K18290	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R02491,R05076	RC00730,RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
SRR25158347_k127_1374362_0	313606.M23134_07816	7.038e-70	246.0	COG3000@1|root,COG3000@2|Bacteria,4NI62@976|Bacteroidetes,47NVG@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158347_k127_1374362_2	56110.Oscil6304_4527	2.542e-32	130.0	COG0745@1|root,COG2114@1|root,COG4252@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG4252@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_1378008_1	237368.SCABRO_01013	8.539e-07	55.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158347_k127_1378008_0	697281.Mahau_1737	1.313e-72	256.0	COG4223@1|root,COG4223@2|Bacteria,1TSFB@1239|Firmicutes,24BRS@186801|Clostridia,42FM0@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4380)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1378324_0	1282876.BAOK01000002_gene265	1.755e-49	184.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_1378324_1	1304284.L21TH_1778	3.093e-18	89.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
SRR25158347_k127_1384253_2	237368.SCABRO_03849	2.219e-15	76.0	COG0767@1|root,COG0767@2|Bacteria,2IX01@203682|Planctomycetes	203682|Planctomycetes	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158347_k127_1384253_0	237368.SCABRO_03848	3.408e-100	333.0	COG1127@1|root,COG1127@2|Bacteria,2J2WI@203682|Planctomycetes	203682|Planctomycetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158347_k127_1384253_1	237368.SCABRO_03847	2.326e-45	172.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	iamC	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158347_k127_1384518_0	373994.Riv7116_1316	2.393e-200	655.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1G4QT@1117|Cyanobacteria,1HKP5@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,Pkinase
SRR25158347_k127_1384518_1	177437.HRM2_08990	8.856e-114	377.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,42T8R@68525|delta/epsilon subdivisions,2WPR7@28221|Deltaproteobacteria,2MMKM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Strictosidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Str_synth
SRR25158347_k127_1385692_0	762903.Pedsa_1491	1.514e-41	159.0	COG0726@1|root,COG0726@2|Bacteria,4NKEH@976|Bacteroidetes,1IRHZ@117747|Sphingobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158347_k127_1385692_1	504472.Slin_5410	9.513e-39	149.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,47JVV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
SRR25158347_k127_1396256_2	1278307.KB906975_gene1921	1.949e-22	100.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QIQ4@267894|Psychromonadaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH,dCache_1
SRR25158347_k127_1396256_1	83406.HDN1F_01800	3.501e-46	171.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1S7F5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158347_k127_1396256_0	580332.Slit_1584	1.129e-46	173.0	COG1871@1|root,COG1871@2|Bacteria,1RI55@1224|Proteobacteria,2VUAC@28216|Betaproteobacteria,44WIV@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
SRR25158347_k127_1401023_1	1173263.Syn7502_00522	9.766e-18	86.0	COG0534@1|root,COG0534@2|Bacteria,1G0XS@1117|Cyanobacteria,1H2G9@1129|Synechococcus	1117|Cyanobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRR25158347_k127_1401023_0	243232.MJ_1066	3.571e-111	372.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23QJ1@183939|Methanococci	183939|Methanococci	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158347_k127_1402240_0	1122221.JHVI01000009_gene2699	4.766e-104	351.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	sqr	GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_1402240_1	452637.Oter_4097	2.007e-75	263.0	COG0385@1|root,COG0385@2|Bacteria,46YMH@74201|Verrucomicrobia,3K9UA@414999|Opitutae	414999|Opitutae	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
SRR25158347_k127_1402240_2	1288494.EBAPG3_11750	4.007e-11	71.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE,KAP_NTPase,PG_binding_1,WD40
SRR25158347_k127_1408904_0	1235803.C825_01924	0.0001622	52.0	COG2755@1|root,COG2755@2|Bacteria,4NM85@976|Bacteroidetes,2FRW3@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1409655_0	1408439.JHXW01000006_gene1010	5.171e-27	125.0	COG2208@1|root,COG2208@2|Bacteria,378YN@32066|Fusobacteria	32066|Fusobacteria	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,Response_reg,SpoIIE
SRR25158347_k127_1411050_0	1337936.IJ00_03220	1.087e-82	285.0	COG1398@1|root,COG1398@2|Bacteria,1G100@1117|Cyanobacteria,1HJB1@1161|Nostocales	1117|Cyanobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158347_k127_141138_0	530564.Psta_2657	1.26e-170	542.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,2IY13@203682|Planctomycetes	203682|Planctomycetes	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
SRR25158347_k127_141138_1	1123274.KB899414_gene3638	5.724e-05	46.0	COG0664@1|root,COG2172@1|root,COG0664@2|Bacteria,COG2172@2|Bacteria,2J5ZY@203691|Spirochaetes	203691|Spirochaetes	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,cNMP_binding
SRR25158347_k127_1414204_0	338966.Ppro_0615	7.63e-07	55.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,43U0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158347_k127_1414289_0	3641.EOY31428	0.0001041	53.0	KOG0498@1|root,KOG0498@2759|Eukaryota,37ZHV@33090|Viridiplantae,3GE9V@35493|Streptophyta	35493|Streptophyta	PT	KHA, dimerisation domain of potassium ion channel	-	-	-	ko:K21867	-	-	-	-	ko00000,ko02000	1.A.1.4	-	-	Ank_2,Ion_trans,KHA,cNMP_binding
SRR25158347_k127_1414751_1	288000.BBta_3744	4.708e-13	69.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1N0V5@1224|Proteobacteria,2TUDA@28211|Alphaproteobacteria,3K3DN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
SRR25158347_k127_1414751_0	1392540.P256_01838	5.564e-39	148.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,3NJUR@468|Moraxellaceae	1236|Gammaproteobacteria	C	FAD linked oxidases, C-terminal domain	IV02_25675	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158347_k127_1415498_0	756067.MicvaDRAFT_2559	1.057e-67	243.0	COG0515@1|root,COG2208@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	2|Bacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	pkn5	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase,SpoIIE
SRR25158347_k127_1417861_2	204669.Acid345_4447	0.0001975	48.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRR25158347_k127_1417861_1	1379698.RBG1_1C00001G0979	9.341e-77	265.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158347_k127_1417861_0	313606.M23134_01938	5.625e-108	362.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,Pkinase
SRR25158347_k127_1423389_0	743299.Acife_3160	2.027e-28	124.0	COG3239@1|root,COG3239@2|Bacteria	2|Bacteria	I	unsaturated fatty acid biosynthetic process	desA3	GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	iJN678.desD_des6_	FA_desaturase
SRR25158347_k127_1423389_1	1236959.BAMT01000002_gene2228	4.086e-24	105.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KKF2@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,SBP_bac_3
SRR25158347_k127_142606_0	903818.KI912268_gene1325	2.59e-46	182.0	COG1074@1|root,COG1074@2|Bacteria,3Y41J@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158347_k127_1427841_0	517417.Cpar_1236	1.15e-143	470.0	COG0591@1|root,COG0591@2|Bacteria,1FD9H@1090|Chlorobi	1090|Chlorobi	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158347_k127_1427841_1	720554.Clocl_3923	6.226e-38	144.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3WGQE@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158347_k127_142992_0	177437.HRM2_p00230	1.085e-50	188.0	COG0784@1|root,COG3852@1|root,COG4564@1|root,COG0784@2|Bacteria,COG3852@2|Bacteria,COG4564@2|Bacteria,1NC9X@1224|Proteobacteria,43BKK@68525|delta/epsilon subdivisions,2X6YN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158347_k127_1432838_0	246194.CHY_1839	7.092e-178	570.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,42FD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158347_k127_1432838_1	869209.Tresu_1240	2.445e-69	246.0	COG1235@1|root,COG1235@2|Bacteria,2J5C5@203691|Spirochaetes	203691|Spirochaetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_1432838_3	196164.23493043	1.06e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,2HQ3E@201174|Actinobacteria,22QJW@1653|Corynebacteriaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158347_k127_1432838_2	153721.MYP_771	1.265e-66	231.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,47K0F@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
SRR25158347_k127_1435746_0	1536772.R70723_00560	1.892e-82	285.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26R9D@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158347_k127_1436209_0	5911.EAS00306	2.701e-202	651.0	COG3808@1|root,2QPJC@2759|Eukaryota,3ZBG4@5878|Ciliophora	5878|Ciliophora	C	Inorganic H+ pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	H_PPase
SRR25158347_k127_1436209_1	194439.CT1487	1.138e-42	165.0	COG2890@1|root,COG2890@2|Bacteria,1FD5X@1090|Chlorobi	1090|Chlorobi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158347_k127_1439360_1	395493.BegalDRAFT_2292	6.363e-21	104.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	pkn5	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,Pkinase,SpoIIE,dCache_1
SRR25158347_k127_1439360_0	1184267.A11Q_2051	2.143e-37	158.0	COG1352@1|root,COG1352@2|Bacteria,1QY2J@1224|Proteobacteria,43AK1@68525|delta/epsilon subdivisions,2MTJG@213481|Bdellovibrionales,2X60B@28221|Deltaproteobacteria	213481|Bdellovibrionales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1439955_0	1167006.UWK_00592	7.924e-115	390.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2WJTI@28221|Deltaproteobacteria,2MJ12@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
SRR25158347_k127_1440786_0	1234679.BN424_2901	1.956e-63	222.0	COG3803@1|root,COG3803@2|Bacteria,1V3Y2@1239|Firmicutes,4HH81@91061|Bacilli,27HAK@186828|Carnobacteriaceae	91061|Bacilli	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
SRR25158347_k127_1443209_0	1123057.P872_24745	2.788e-29	125.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
SRR25158347_k127_1443209_1	926556.Echvi_0907	2.397e-05	49.0	COG1918@1|root,COG1918@2|Bacteria,4NXQJ@976|Bacteroidetes,47T2F@768503|Cytophagia	976|Bacteroidetes	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SRR25158347_k127_1446232_0	489825.LYNGBM3L_45100	1.067e-115	382.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1H7FT@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Nucleos_tra2_C,Nucleos_tra2_N
SRR25158347_k127_1449798_0	373994.Riv7116_5480	3.217e-164	532.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HTTD@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_1451869_0	111781.Lepto7376_1561	6.411e-33	137.0	COG3675@1|root,COG3675@2|Bacteria,1G7WY@1117|Cyanobacteria,1HD7F@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Lipase, class 3	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
SRR25158347_k127_1453721_0	479434.Sthe_3028	1.595e-107	366.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158347_k127_1454813_0	402777.KB235903_gene1652	4.959e-98	327.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_1460861_1	857293.CAAU_0607	5.855e-14	83.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Big_2,CBM_20,CBM_48,Cadherin-like,Malt_amylase_C,PUD,SLH
SRR25158347_k127_1460861_0	290315.Clim_1609	6.802e-32	131.0	COG1216@1|root,COG1216@2|Bacteria,1FEIB@1090|Chlorobi	1090|Chlorobi	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_1464981_0	314278.NB231_17423	1.806e-137	445.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1WW4Z@135613|Chromatiales	135613|Chromatiales	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
SRR25158347_k127_1466841_0	1476583.DEIPH_ctg029orf0043	2.202e-10	72.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
SRR25158347_k127_1469050_0	592029.DDD_0039	2.216e-71	252.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158347_k127_1472168_0	1124983.PFLCHA0_c30570	1.459e-12	74.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1472273_0	391625.PPSIR1_16700	1.069e-110	365.0	COG1996@1|root,COG1996@2|Bacteria,1QV33@1224|Proteobacteria,43CNA@68525|delta/epsilon subdivisions,2X7VK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1480889_1	889378.Spiaf_2340	3.781e-24	108.0	COG0811@1|root,COG0811@2|Bacteria,2J7RG@203691|Spirochaetes	203691|Spirochaetes	U	Biopolymer transport protein	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158347_k127_1480889_4	908612.HMPREF9720_2422	3.31e-06	54.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22UGQ@171550|Rikenellaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
SRR25158347_k127_1480889_2	1250005.PHEL85_1430	3.614e-09	63.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia,3VWIN@52959|Polaribacter	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158347_k127_1480889_3	404589.Anae109_0870	1.536e-08	63.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SRR25158347_k127_1480889_0	349521.HCH_03837	1.83e-39	148.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria,1RQCX@1236|Gammaproteobacteria,1XNQW@135619|Oceanospirillales	135619|Oceanospirillales	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158347_k127_1483166_3	381046.XP_002551607.1	2.746e-10	70.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3QKI5@4890|Ascomycota,3RSCY@4891|Saccharomycetes,3RYS1@4893|Saccharomycetaceae	4751|Fungi	T	cAMP-dependent protein kinase regulatory subunit	PKAR	GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRR25158347_k127_1483166_0	1189612.A33Q_4430	3.581e-40	154.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,47R52@768503|Cytophagia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158347_k127_1483166_2	634956.Geoth_2448	2.494e-36	149.0	COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,1WFGV@129337|Geobacillus	91061|Bacilli	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158347_k127_1483166_1	1168034.FH5T_12565	8.687e-37	143.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia	976|Bacteroidetes	E	Lao Ao transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158347_k127_1484677_0	269799.Gmet_0951	7.673e-216	683.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,43UIT@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158347_k127_1486460_2	485918.Cpin_1567	1.353e-99	336.0	28M67@1|root,2ZAJW@2|Bacteria,4NF2D@976|Bacteroidetes,1ISM2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1486460_1	153721.MYP_1541	2.43e-145	478.0	COG1231@1|root,COG1231@2|Bacteria,4NJP2@976|Bacteroidetes,47XWR@768503|Cytophagia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158347_k127_1486460_0	153721.MYP_1542	3.498e-202	640.0	COG4262@1|root,COG4262@2|Bacteria,4NFVH@976|Bacteroidetes,47NJJ@768503|Cytophagia	976|Bacteroidetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158347_k127_1492148_1	1137799.GZ78_16455	7.594e-30	121.0	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XHID@135619|Oceanospirillales	135619|Oceanospirillales	E	catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids	avtA	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158347_k127_1492148_0	344747.PM8797T_28884	5.85e-46	174.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158347_k127_1498085_2	187303.BN69_2885	2.043e-08	58.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,36YCG@31993|Methylocystaceae	28211|Alphaproteobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158347_k127_1498085_1	880072.Desac_2172	5.971e-10	63.0	arCOG07300@1|root,2ZTGG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1498085_0	880072.Desac_2171	3.954e-89	316.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
SRR25158347_k127_1501681_0	1239962.C943_03379	2.716e-128	416.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,47JGI@768503|Cytophagia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158347_k127_1502286_0	1120951.AUBG01000017_gene3273	4.766e-18	96.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_1503621_1	1317122.ATO12_24585	5.989e-31	126.0	COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,1I2P2@117743|Flavobacteriia,2YIQT@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158347_k127_1503621_0	795359.TOPB45_1154	1.275e-51	194.0	COG0557@1|root,COG0557@2|Bacteria,2GH2N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158347_k127_1505230_0	1173029.JH980292_gene2348	1.169e-204	660.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
SRR25158347_k127_1505230_2	1189612.A33Q_1797	4.357e-10	70.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158347_k127_1505230_1	56107.Cylst_0492	1.344e-19	100.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_1505230_3	394503.Ccel_2027	1.1e-09	59.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,36DR0@31979|Clostridiaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
SRR25158347_k127_1508326_0	497964.CfE428DRAFT_0737	4.166e-89	309.0	COG0265@1|root,COG0265@2|Bacteria,46UAN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_1509567_1	1237149.C900_05712	4.818e-73	252.0	COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,47KDA@768503|Cytophagia	976|Bacteroidetes	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158347_k127_1509567_0	313606.M23134_00340	6.006e-153	494.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,47JJI@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR25158347_k127_1509996_1	29730.Gorai.011G226900.1	1.14e-22	105.0	KOG1638@1|root,KOG1638@2759|Eukaryota,37R41@33090|Viridiplantae,3GH47@35493|Streptophyta	35493|Streptophyta	I	3-oxo-5-alpha-steroid 4-dehydrogenase	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0003865,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006629,GO:0006694,GO:0006702,GO:0007154,GO:0007267,GO:0007275,GO:0007548,GO:0008150,GO:0008152,GO:0008202,GO:0008207,GO:0008209,GO:0008406,GO:0008584,GO:0008610,GO:0009058,GO:0009917,GO:0009987,GO:0010817,GO:0012505,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016627,GO:0017144,GO:0022414,GO:0023052,GO:0030283,GO:0030539,GO:0030540,GO:0031984,GO:0032501,GO:0032502,GO:0033764,GO:0033765,GO:0034754,GO:0042175,GO:0042180,GO:0042181,GO:0042445,GO:0042446,GO:0042448,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045137,GO:0046546,GO:0046660,GO:0046661,GO:0048513,GO:0048608,GO:0048731,GO:0048806,GO:0048856,GO:0055114,GO:0061370,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0098827,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	1.3.1.22,1.3.1.93	ko:K10258,ko:K12343	ko00062,ko00140,ko01040,ko01110,ko01212,map00062,map00140,map01040,map01110,map01212	M00415	R02208,R02497,R07761,R08954,R09449,R10242,R10828	RC00052,RC00120,RC00145	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Steroid_dh
SRR25158347_k127_1509996_0	83406.HDN1F_18440	2.68e-122	413.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.13.12.3	ko:K00466,ko:K09879	ko00380,ko00906,map00380,map00906	-	R00679,R07541,R07560,R07857,R07858	RC00213,RC01901,RC01965	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,DAO
SRR25158347_k127_1509996_2	929703.KE386491_gene866	3.152e-09	68.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,47M50@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
SRR25158347_k127_1513526_0	929562.Emtol_3328	4.534e-185	587.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158347_k127_1517129_0	755178.Cyan10605_0254	6.157e-40	158.0	COG1434@1|root,COG1434@2|Bacteria,1G1QC@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158347_k127_1517129_1	237727.NAP1_14958	1.782e-24	113.0	COG0596@1|root,COG0596@2|Bacteria,1RD9Q@1224|Proteobacteria,2TW3W@28211|Alphaproteobacteria,2KEA4@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158347_k127_1519203_0	330214.NIDE3717	6.258e-20	92.0	COG0607@1|root,COG0607@2|Bacteria,3J17U@40117|Nitrospirae	40117|Nitrospirae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158347_k127_1519203_1	1392498.JQLH01000001_gene2652	5.068e-05	54.0	COG3103@1|root,COG3103@2|Bacteria,4NU2A@976|Bacteroidetes,1I4GG@117743|Flavobacteriia,2PI36@252356|Maribacter	976|Bacteroidetes	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158347_k127_1520912_1	1121405.dsmv_0468	3.04e-64	233.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2MIF7@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
SRR25158347_k127_1520912_0	1121403.AUCV01000020_gene3073	5.316e-152	497.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SRR25158347_k127_1521234_1	941824.TCEL_01635	5.26e-49	181.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,36EHG@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_1521234_3	1304880.JAGB01000001_gene194	6.563e-13	70.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia	186801|Clostridia	N	PFAM flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
SRR25158347_k127_1521234_0	665571.STHERM_c09200	1.765e-74	258.0	COG1291@1|root,COG1291@2|Bacteria,2J5HT@203691|Spirochaetes	203691|Spirochaetes	N	MotA TolQ ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
SRR25158347_k127_1521234_2	1480694.DC28_02380	3.713e-30	122.0	COG1360@1|root,COG1360@2|Bacteria,2J68Q@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158347_k127_1521705_0	313628.LNTAR_01055	1.579e-126	417.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
SRR25158347_k127_1523644_0	1249997.JHZW01000002_gene1740	9.555e-15	78.0	COG1501@1|root,COG1501@2|Bacteria,4NJ93@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Glyco_hydro_31
SRR25158347_k127_1527397_0	999419.HMPREF1077_02792	2.815e-108	359.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22W2U@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158347_k127_1527397_1	1121895.Q765_14870	9.965e-46	176.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia,2NSFG@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158347_k127_1527631_2	112098.XP_008617979.1	0.0003135	50.0	KOG0274@1|root,KOG0274@2759|Eukaryota	2759|Eukaryota	M	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	sconB	GO:0000082,GO:0000083,GO:0000151,GO:0000152,GO:0000209,GO:0000278,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006355,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010498,GO:0010556,GO:0016567,GO:0019005,GO:0019219,GO:0019222,GO:0019538,GO:0019941,GO:0022402,GO:0030163,GO:0030174,GO:0030674,GO:0031146,GO:0031323,GO:0031326,GO:0031461,GO:0032182,GO:0032446,GO:0032991,GO:0034641,GO:0034645,GO:0036211,GO:0042221,GO:0043130,GO:0043161,GO:0043170,GO:0043224,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046483,GO:0046685,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051252,GO:0051603,GO:0060090,GO:0060255,GO:0065007,GO:0070647,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902494,GO:1903047,GO:1903506,GO:1990234,GO:2000112,GO:2001141	2.3.2.26	ko:K10259,ko:K10260,ko:K10592	ko04111,ko04120,map04111,map04120	M00379,M00387	-	-	ko00000,ko00001,ko00002,ko01000,ko04121,ko04131	-	-	-	F-box,F-box-like,WD40
SRR25158347_k127_1527631_0	869213.JCM21142_93839	7.168e-38	154.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158347_k127_1527631_1	1008459.TASI_0626	1.844e-33	133.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,3T3X7@506|Alcaligenaceae	28216|Betaproteobacteria	S	Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158347_k127_1528450_0	1379281.AVAG01000026_gene1636	1.01e-130	432.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2M91Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158347_k127_1528450_1	889378.Spiaf_2666	2.639e-51	193.0	COG5000@1|root,COG5000@2|Bacteria,2J753@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_1528526_0	102125.Xen7305DRAFT_00023600	3.204e-52	202.0	COG0668@1|root,COG0683@1|root,COG0668@2|Bacteria,COG0683@2|Bacteria,1G1WJ@1117|Cyanobacteria	1117|Cyanobacteria	E	ABC-type branched-chain amino acid transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_1528526_1	926550.CLDAP_00150	4.559e-07	62.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
SRR25158347_k127_1528960_0	1201288.M900_1005	2.358e-44	174.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,42Y3Q@68525|delta/epsilon subdivisions,2MTU8@213481|Bdellovibrionales,2WT53@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
SRR25158347_k127_1529607_0	391596.PBAL39_14774	2.544e-82	286.0	COG5002@1|root,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1IR2A@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_1529804_0	203122.Sde_2271	8.934e-58	218.0	COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,1RRFW@1236|Gammaproteobacteria,46B7W@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295,ICMT
SRR25158347_k127_1530053_0	13035.Dacsa_0276	9.381e-20	92.0	COG0639@1|root,COG0639@2|Bacteria,1G6GN@1117|Cyanobacteria	1117|Cyanobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
SRR25158347_k127_1534395_2	1121904.ARBP01000005_gene4640	2.038e-05	50.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes,47THS@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
SRR25158347_k127_1534395_0	1123371.ATXH01000003_gene1967	6.11e-158	511.0	COG1220@1|root,COG1220@2|Bacteria,2GGX7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158347_k127_1534395_1	742743.HMPREF9453_00828	7.101e-22	95.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H3KQ@909932|Negativicutes	909932|Negativicutes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158347_k127_1534942_1	1026882.MAMP_00817	6.306e-14	76.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,1RQ8J@1236|Gammaproteobacteria,463NS@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_1534942_0	755178.Cyan10605_3252	1.922e-78	267.0	COG0225@1|root,COG0225@2|Bacteria,1G5XQ@1117|Cyanobacteria	1117|Cyanobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158347_k127_1535624_0	1168034.FH5T_20810	5.308e-98	341.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FRUD@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,Response_reg
SRR25158347_k127_1535932_0	1173022.Cri9333_0020	3.422e-152	504.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1G26V@1117|Cyanobacteria,1H78U@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_1535932_1	179408.Osc7112_1908	5.707e-61	218.0	COG2201@1|root,COG2201@2|Bacteria,1G1EA@1117|Cyanobacteria,1H8DX@1150|Oscillatoriales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158347_k127_1538796_0	243231.GSU2066	4.433e-57	203.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,43T8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158347_k127_15443_1	1288494.EBAPG3_11750	2.068e-11	73.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE,KAP_NTPase,PG_binding_1,WD40
SRR25158347_k127_15443_0	1173028.ANKO01000017_gene82	3.086e-92	334.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_1546041_2	485913.Krac_9046	3.582e-21	94.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158347_k127_1546041_1	1123326.JFBL01000011_gene186	8.439e-47	173.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158347_k127_1546041_0	1123277.KB893178_gene2551	3.77e-146	473.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,47KBK@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158347_k127_1547464_1	1235800.C819_01204	3.266e-11	66.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,27IB6@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
SRR25158347_k127_1547464_0	373903.Hore_22570	5.706e-81	281.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia,3WB3V@53433|Halanaerobiales	186801|Clostridia	NT	CheB methylesterase	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158347_k127_1550369_0	1121877.JQKF01000013_gene297	2.594e-26	110.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria,4CNB4@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158347_k127_1550369_2	1207063.P24_01115	4.317e-16	79.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,2TRW4@28211|Alphaproteobacteria,2JPEM@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
SRR25158347_k127_1550369_4	400668.Mmwyl1_3799	6.533e-08	59.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria,1XIDF@135619|Oceanospirillales	135619|Oceanospirillales	CP	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M
SRR25158347_k127_1550369_3	243090.RB1134	8.865e-13	73.0	COG1009@1|root,COG1009@2|Bacteria,2IZ3F@203682|Planctomycetes	203682|Planctomycetes	C	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L)	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_1550369_1	1034807.FBFL15_1712	6.015e-21	100.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia,2NTHT@237|Flavobacterium	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_1550635_0	1201288.M900_0183	8.183e-06	57.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2MSZT@213481|Bdellovibrionales,2WKKE@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SRR25158347_k127_1551827_2	1304888.ATWF01000002_gene515	7.5e-09	64.0	COG2844@1|root,COG2844@2|Bacteria,2GERY@200930|Deferribacteres	200930|Deferribacteres	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	GlnD_UR_UTase,HD
SRR25158347_k127_1551827_0	1280680.AUJU01000001_gene1629	8.059e-44	171.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,4BXDR@830|Butyrivibrio	186801|Clostridia	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158347_k127_1551827_3	879212.DespoDRAFT_01475	1.045e-05	51.0	COG5464@1|root,COG5464@2|Bacteria,1MUSP@1224|Proteobacteria,42RIE@68525|delta/epsilon subdivisions,2WNU1@28221|Deltaproteobacteria,2MN5D@213118|Desulfobacterales	28221|Deltaproteobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
SRR25158347_k127_1551827_1	572479.Hprae_1864	1.029e-32	134.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,248B2@186801|Clostridia	186801|Clostridia	S	transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
SRR25158347_k127_1552751_0	1173028.ANKO01000052_gene1623	4.599e-174	579.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GC6Z@1117|Cyanobacteria,1H6Y9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_1553460_0	153721.MYP_2606	1.165e-62	224.0	2CAD1@1|root,2Z81J@2|Bacteria,4NJ4C@976|Bacteroidetes,47PTB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1553460_2	1123037.AUDE01000019_gene3343	1.57e-08	63.0	2F1YU@1|root,33UY6@2|Bacteria,4P2VN@976|Bacteroidetes,1I8MH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1553460_1	1033810.HLPCO_000959	2.442e-32	137.0	COG1948@1|root,COG4880@2|Bacteria	2|Bacteria	L	resolution of meiotic recombination intermediates	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRR25158347_k127_1557130_1	1125863.JAFN01000001_gene796	4.344e-19	97.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1557130_0	2340.JV46_19900	8.551e-50	184.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,1S834@1236|Gammaproteobacteria,1JAI4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
SRR25158347_k127_155993_0	332101.JIBU02000021_gene1909	2.82e-21	98.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
SRR25158347_k127_1560854_0	1121104.AQXH01000001_gene1960	0.0	1032.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1J0XB@117747|Sphingobacteriia	976|Bacteroidetes	I	methylmalonyl-CoA mutase N-terminal domain	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158347_k127_1560854_1	667014.Thein_0926	4.665e-17	87.0	COG0840@1|root,COG2703@1|root,COG3850@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,COG3850@2|Bacteria,2GIDC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NPT	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,MCPsignal,PilJ
SRR25158347_k127_1560854_2	1198232.CYCME_1737	4.141e-15	81.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,460KS@72273|Thiotrichales	72273|Thiotrichales	U	MotA TolQ ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158347_k127_1560854_3	1172190.M947_05250	9.408e-06	54.0	COG0848@1|root,COG0848@2|Bacteria,1NN40@1224|Proteobacteria,42XMQ@68525|delta/epsilon subdivisions,2YS4K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158347_k127_1560854_4	765420.OSCT_1694	0.000132	48.0	COG2199@1|root,COG3706@2|Bacteria,2GAEA@200795|Chloroflexi,375RZ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_1567182_1	886293.Sinac_6391	5.877e-56	202.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158347_k127_1567182_0	1049564.TevJSym_ad01420	1.644e-122	399.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1J5JA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158347_k127_1568367_0	1480694.DC28_02030	4.713e-100	342.0	COG0532@1|root,COG0532@2|Bacteria,2J692@203691|Spirochaetes	203691|Spirochaetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158347_k127_1569513_0	1121904.ARBP01000010_gene2383	1.208e-161	519.0	COG1251@1|root,COG1251@2|Bacteria,4NE44@976|Bacteroidetes,47M7X@768503|Cytophagia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SRR25158347_k127_1569798_0	929558.SMGD1_0536	9.365e-106	355.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2YTC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158347_k127_1569837_0	159749.K0SWG1	2.709e-72	256.0	2ECT4@1|root,2SIJZ@2759|Eukaryota,2XB6B@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1570671_0	1278309.KB907107_gene1679	3.685e-91	323.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XHET@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
SRR25158347_k127_1570671_1	1223410.KN050846_gene174	4.003e-18	87.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1HY1T@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
SRR25158347_k127_1572622_0	929703.KE386491_gene1074	1.057e-45	168.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,Reg_prop,Response_reg,Y_Y_Y
SRR25158347_k127_1573783_0	1358423.N180_15295	2.171e-48	184.0	COG0286@1|root,COG0286@2|Bacteria,4NI6W@976|Bacteroidetes,1ITEH@117747|Sphingobacteriia	976|Bacteroidetes	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase,TaqI_C
SRR25158347_k127_1576064_1	1120951.AUBG01000007_gene140	2.932e-63	221.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,1HY7X@117743|Flavobacteriia	976|Bacteroidetes	U	Carboxypeptidase regulatory-like domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158347_k127_1576064_0	926559.JoomaDRAFT_2567	7.266e-138	439.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158347_k127_1576188_3	880072.Desac_1432	9.711e-12	65.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158347_k127_1576188_2	1121087.AUCK01000006_gene556	6.09e-34	131.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1ZHWN@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158347_k127_1576188_1	936589.HMPREF1521_1755	5.039e-60	213.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4H2UG@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158347_k127_1576188_0	671143.DAMO_0559	7.565e-116	387.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158347_k127_157772_0	1042377.AFPJ01000024_gene742	9.158e-75	273.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,465FW@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_1578035_0	661478.OP10G_4294	1.084e-36	150.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158347_k127_1578196_0	1434325.AZQN01000001_gene261	7.157e-45	169.0	COG0494@1|root,COG0494@2|Bacteria,4NM2N@976|Bacteroidetes,47NYX@768503|Cytophagia	976|Bacteroidetes	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_1578339_0	479434.Sthe_0444	2.575e-12	76.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
SRR25158347_k127_1584433_1	869213.JCM21142_41591	7.9e-20	89.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,47M21@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158347_k127_1584433_0	290317.Cpha266_2085	6.796e-100	331.0	COG1432@1|root,COG1432@2|Bacteria,1FECY@1090|Chlorobi	1090|Chlorobi	NU	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158347_k127_158444_0	1499968.TCA2_4166	5.343e-29	123.0	COG3613@1|root,COG3613@2|Bacteria,1VFK6@1239|Firmicutes	1239|Firmicutes	F	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
SRR25158347_k127_158444_1	215803.DB30_6245	2.758e-06	59.0	293FU@1|root,2ZQY7@2|Bacteria,1PAUE@1224|Proteobacteria,437XW@68525|delta/epsilon subdivisions,2X9RN@28221|Deltaproteobacteria,2YUR8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1585673_0	1304880.JAGB01000002_gene1641	1.054e-142	466.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158347_k127_1585673_3	65093.PCC7418_0806	2.563e-07	53.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1585673_1	13333.ERN04208	6.487e-22	98.0	COG0661@1|root,KOG1235@2759|Eukaryota,37IRM@33090|Viridiplantae,3G80B@35493|Streptophyta	35493|Streptophyta	S	aarF domain-containing protein kinase At5g05200	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0010287,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	ko:K08869	-	-	-	-	ko00000,ko01001	-	-	-	ABC1
SRR25158347_k127_1585673_2	1201288.M900_2384	1.025e-18	87.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158347_k127_158938_0	1396418.BATQ01000056_gene180	1.364e-15	90.0	COG2982@1|root,COG2982@2|Bacteria,46XT1@74201|Verrucomicrobia,2IWHV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1589606_0	32057.KB217478_gene1658	3.647e-74	260.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
SRR25158347_k127_1590620_1	862908.BMS_2594	1.122e-07	54.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,42QST@68525|delta/epsilon subdivisions,2MTF5@213481|Bdellovibrionales,2WMN8@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
SRR25158347_k127_1590620_0	1121935.AQXX01000121_gene5543	1.626e-163	521.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XIMQ@135619|Oceanospirillales	135619|Oceanospirillales	C	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid	betB	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_1590890_2	983545.Glaag_4249	1.31e-28	117.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,1T1UP@1236|Gammaproteobacteria,46DB1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1590890_3	1196324.A374_19110	1.533e-10	62.0	COG4221@1|root,COG4221@2|Bacteria,1V5I6@1239|Firmicutes,4HHCR@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1590890_1	1305737.JAFX01000001_gene1662	5.553e-37	142.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158347_k127_1590890_0	83406.HDN1F_15990	2.087e-235	735.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1J4JG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	-	-	5.4.99.2,5.4.99.63	ko:K01847,ko:K14447	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158347_k127_1591228_2	671143.DAMO_2121	6.578e-43	165.0	COG0635@1|root,COG2267@1|root,COG0635@2|Bacteria,COG2267@2|Bacteria,2NRGT@2323|unclassified Bacteria	2|Bacteria	H	Elongator protein 3, MiaB family, Radical SAM	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4,Radical_SAM
SRR25158347_k127_1591228_4	5911.EAR88262	8.813e-11	75.0	COG0664@1|root,KOG1113@2759|Eukaryota,3ZEWJ@5878|Ciliophora	5878|Ciliophora	T	cAMP-dependent protein kinase regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158347_k127_1591228_5	906968.Trebr_1460	7.027e-08	65.0	COG0664@1|root,COG0664@2|Bacteria,2J5G6@203691|Spirochaetes	203691|Spirochaetes	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158347_k127_1591228_3	1408433.JHXV01000028_gene2164	5.322e-25	110.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1I2T1@117743|Flavobacteriia,2PBYR@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
SRR25158347_k127_1591228_0	1273538.G159_08330	2.768e-54	199.0	COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,26F8G@186818|Planococcaceae	91061|Bacilli	GM	Nucleoside-diphosphate-sugar epimerases	M1-688	-	-	-	-	-	-	-	-	-	-	-	Epimerase,HIM1,NAD_binding_10
SRR25158347_k127_1591228_1	1449126.JQKL01000001_gene1497	6.375e-51	187.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,267II@186813|unclassified Clostridiales	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158347_k127_1595799_0	1304885.AUEY01000023_gene2661	9.381e-198	621.0	COG1653@1|root,COG1653@2|Bacteria,1MV8A@1224|Proteobacteria,42N6A@68525|delta/epsilon subdivisions,2WK4K@28221|Deltaproteobacteria,2MIW4@213118|Desulfobacterales	68525|delta/epsilon subdivisions	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17321	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	-
SRR25158347_k127_1595799_1	1121033.AUCF01000033_gene3619	7.848e-12	70.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JQ44@204441|Rhodospirillales	204441|Rhodospirillales	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
SRR25158347_k127_1598471_1	582515.KR51_00019120	2.943e-15	80.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158347_k127_1598471_0	28229.ND2E_1822	4.874e-139	450.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,2Q7UY@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9
SRR25158347_k127_1601419_0	926551.KB900703_gene1010	1.911e-33	137.0	28HG9@1|root,2Z7S5@2|Bacteria,4NF7W@976|Bacteroidetes,1I32B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1601419_1	297246.lpp1704	0.0003157	46.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1JCGE@118969|Legionellales	118969|Legionellales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158347_k127_160677_0	411154.GFO_0376	1.446e-69	237.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
SRR25158347_k127_160677_1	1121931.AUHG01000013_gene2456	2.622e-60	209.0	2DZUU@1|root,32VJK@2|Bacteria,4NTH9@976|Bacteroidetes,1I415@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1607618_0	525904.Tter_1216	2.666e-253	796.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158347_k127_1609214_0	1048983.EL17_15215	1.343e-69	247.0	COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,47MZX@768503|Cytophagia	976|Bacteroidetes	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158347_k127_1610087_0	580340.Tlie_0581	3.654e-46	177.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,3T9T4@508458|Synergistetes	508458|Synergistetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR25158347_k127_161166_1	1410608.JNKX01000008_gene1317	4.986e-36	144.0	COG4942@1|root,COG4942@2|Bacteria,4P0BC@976|Bacteroidetes,2FPSC@200643|Bacteroidia,4AQ2N@815|Bacteroidaceae	976|Bacteroidetes	D	Protein of unknown function (DUF3375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
SRR25158347_k127_161166_0	1121859.KB890757_gene1570	3.939e-46	173.0	2CB46@1|root,31GHU@2|Bacteria,4P0TC@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
SRR25158347_k127_1615238_1	1540257.JQMW01000004_gene655	3.205e-35	142.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,36F97@31979|Clostridiaceae	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgm	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158347_k127_1615238_0	1158318.ATXC01000001_gene421	1.078e-70	247.0	COG4992@1|root,COG4992@2|Bacteria,2G3V4@200783|Aquificae	200783|Aquificae	E	acetylornithine and succinylornithine aminotransferase	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_1616501_0	745014.OMB55_00020090	1.04e-35	145.0	COG2267@1|root,COG2267@2|Bacteria,1QV06@1224|Proteobacteria,1T4A6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_1616501_1	1189612.A33Q_0528	4.15e-06	51.0	2E29H@1|root,32X6D@2|Bacteria,4NSA2@976|Bacteroidetes,47RCG@768503|Cytophagia	976|Bacteroidetes	S	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
SRR25158347_k127_1621380_0	1121890.AUDO01000001_gene694	4.182e-51	198.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1HYR3@117743|Flavobacteriia,2NU1B@237|Flavobacterium	976|Bacteroidetes	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_1622880_0	1307761.L21SP2_1564	3.231e-31	137.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	DUF1493,PP-binding
SRR25158347_k127_1622880_1	1291050.JAGE01000002_gene3562	5.002e-06	50.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158347_k127_1624289_0	221288.JH992901_gene1423	9.864e-66	239.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1G4QT@1117|Cyanobacteria,1JJWQ@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,Pkinase
SRR25158347_k127_1636239_0	1330700.JQNC01000003_gene895	5.882e-94	318.0	COG0489@1|root,COG0489@2|Bacteria,1WIVB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158347_k127_1638857_0	1319815.HMPREF0202_02341	8.364e-82	282.0	COG0317@1|root,COG0317@2|Bacteria,378FY@32066|Fusobacteria	32066|Fusobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158347_k127_1638857_1	1173027.Mic7113_3377	7.398e-52	194.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1H9WN@1150|Oscillatoriales	1117|Cyanobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_1641928_0	391625.PPSIR1_32964	4.728e-128	421.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_1642104_2	484770.UFO1_2516	8.4e-26	114.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4H3RE@909932|Negativicutes	909932|Negativicutes	D	TIGRFAM stage V sporulation protein E, cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158347_k127_1642104_0	1480694.DC28_02250	8.101e-100	337.0	COG0472@1|root,COG0472@2|Bacteria,2J6QK@203691|Spirochaetes	203691|Spirochaetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158347_k127_1642104_1	1236976.JCM16418_1073	3.996e-53	194.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,26R8F@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_1644633_0	1283300.ATXB01000001_gene901	1.511e-93	338.0	COG1404@1|root,COG2931@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,1T2VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OQ	serine protease	avxIA	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
SRR25158347_k127_1644633_1	1122919.KB905628_gene26	2.192e-72	256.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,26R5G@186822|Paenibacillaceae	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158347_k127_16449_1	313606.M23134_01814	1.544e-16	81.0	COG1524@1|root,COG2340@1|root,COG1524@2|Bacteria,COG2340@2|Bacteria,4NSVB@976|Bacteroidetes,47PIF@768503|Cytophagia	976|Bacteroidetes	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158347_k127_16449_0	880071.Fleli_1626	5.413e-78	272.0	COG1075@1|root,COG1075@2|Bacteria,4NR4R@976|Bacteroidetes,47UZJ@768503|Cytophagia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
SRR25158347_k127_1645080_1	7244.FBpp0230171	1.23e-22	98.0	COG0450@1|root,KOG0852@2759|Eukaryota,38B9P@33154|Opisthokonta,3B9IG@33208|Metazoa,3CS1I@33213|Bilateria,41X1P@6656|Arthropoda,3SIJE@50557|Insecta,44Z6N@7147|Diptera,45XTJ@7214|Drosophilidae	33208|Metazoa	O	Peroxiredoxin activity. It is involved in the biological process described with oxidation-reduction process	Jafrac1	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0006950,GO:0006979,GO:0007155,GO:0007275,GO:0007276,GO:0007281,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0008354,GO:0008379,GO:0009056,GO:0009605,GO:0009636,GO:0009987,GO:0009991,GO:0010259,GO:0016209,GO:0016477,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019725,GO:0019953,GO:0022412,GO:0022414,GO:0022610,GO:0030154,GO:0031667,GO:0032501,GO:0032502,GO:0032504,GO:0040011,GO:0042221,GO:0042592,GO:0042594,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045454,GO:0048468,GO:0048609,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051187,GO:0051674,GO:0051704,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386,ko:K13279	ko04146,ko04214,map04146,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158347_k127_1645080_0	1158345.JNLL01000001_gene1440	5.757e-27	126.0	COG0457@1|root,COG0457@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SRR25158347_k127_1648746_0	323259.Mhun_2807	4.369e-22	111.0	arCOG03042@1|root,arCOG03042@2157|Archaea,2Y7NV@28890|Euryarchaeota	28890|Euryarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRR25158347_k127_1651079_0	1173027.Mic7113_0733	1.347e-65	236.0	COG0745@1|root,COG2208@1|root,COG3452@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,SpoIIE
SRR25158347_k127_165182_2	1254432.SCE1572_00390	9.615e-16	83.0	COG3427@1|root,COG3427@2|Bacteria,1N10Z@1224|Proteobacteria	1224|Proteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_165182_0	313603.FB2170_02890	3.857e-87	296.0	29H98@1|root,3046S@2|Bacteria,4NPW0@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158347_k127_165182_1	485915.Dret_1630	9.444e-20	90.0	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,42XZ1@68525|delta/epsilon subdivisions,2WTGJ@28221|Deltaproteobacteria,2ME5V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158347_k127_165182_3	1541959.KQ51_01569	1.457e-08	59.0	2EYYJ@1|root,33S5A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_165340_0	868864.Dester_0581	9.172e-60	231.0	COG2844@1|root,COG2844@2|Bacteria,2G3VT@200783|Aquificae	200783|Aquificae	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
SRR25158347_k127_1657853_0	1123248.KB893370_gene5134	2.365e-100	338.0	COG1231@1|root,COG1231@2|Bacteria,4NH02@976|Bacteroidetes	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158347_k127_1661152_0	1165841.SULAR_03697	5.976e-100	329.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
SRR25158347_k127_1661152_1	1165841.SULAR_03702	8.211e-44	164.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM MOFRL domain protein	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158347_k127_1665534_0	1185653.A1A1_06742	6.623e-26	115.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli,26EG4@186818|Planococcaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_1669661_0	1280681.AUJZ01000032_gene1805	2.006e-119	411.0	COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,24BQK@186801|Clostridia,4BWN0@830|Butyrivibrio	186801|Clostridia	O	Holliday junction DNA helicase ruvB N-terminus	spoVK	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158347_k127_1674801_0	395493.BegalDRAFT_1395	1.478e-100	345.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S02V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Papain cysteine protease family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
SRR25158347_k127_1688982_1	1280688.AUJB01000008_gene781	4.178e-27	128.0	COG4676@1|root,COG4676@2|Bacteria,1VF8Z@1239|Firmicutes,24S72@186801|Clostridia	186801|Clostridia	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11
SRR25158347_k127_1688982_0	880070.Cycma_2667	4.708e-136	440.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,47K34@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158347_k127_1691250_2	1250278.JQNQ01000001_gene1116	2.521e-72	249.0	COG1216@1|root,COG1216@2|Bacteria,4NKMR@976|Bacteroidetes,1HXG1@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158347_k127_1691250_0	1270193.JARP01000003_gene1960	1.677e-104	347.0	COG1216@1|root,COG1216@2|Bacteria,4NJ4N@976|Bacteroidetes,1HYD8@117743|Flavobacteriia,2NUMA@237|Flavobacterium	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_1691250_1	376686.Fjoh_0316	1.791e-84	288.0	COG1216@1|root,COG1216@2|Bacteria,4NNV5@976|Bacteroidetes,1I2TP@117743|Flavobacteriia,2NVZ9@237|Flavobacterium	976|Bacteroidetes	S	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5
SRR25158347_k127_1691250_3	886379.AEWI01000019_gene1225	5.85e-44	174.0	COG0438@1|root,COG0438@2|Bacteria,4NMHC@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_5,Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_1691250_4	1270193.JARP01000003_gene1955	7.085e-37	145.0	COG0463@1|root,COG0463@2|Bacteria,4NQNJ@976|Bacteroidetes,1I2VG@117743|Flavobacteriia,2NWHQ@237|Flavobacterium	976|Bacteroidetes	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_1693214_0	118168.MC7420_1290	1.968e-81	283.0	COG1162@1|root,COG1162@2|Bacteria,1G18W@1117|Cyanobacteria,1H9XI@1150|Oscillatoriales	1117|Cyanobacteria	S	RsgA GTPase	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158347_k127_1693214_1	1123508.JH636441_gene3692	1.013e-06	59.0	COG1512@1|root,COG1512@2|Bacteria,2J089@203682|Planctomycetes	203682|Planctomycetes	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158347_k127_1700600_0	869213.JCM21142_41446	4.421e-63	231.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_1701469_3	203275.BFO_0895	6.944e-11	66.0	COG0745@1|root,COG0745@2|Bacteria,4NKVJ@976|Bacteroidetes,2FNYS@200643|Bacteroidia,22XHK@171551|Porphyromonadaceae	976|Bacteroidetes	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_1701469_0	566466.NOR53_3254	2.617e-53	210.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T1I4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	cyaA	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158347_k127_1701469_2	1480694.DC28_04495	1.085e-18	91.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	cheX40H	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
SRR25158347_k127_1701469_1	391615.ABSJ01000017_gene1696	5.825e-33	130.0	COG2201@1|root,COG2201@2|Bacteria,1N3V6@1224|Proteobacteria,1SATM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
SRR25158347_k127_1701575_2	754476.Q7A_2679	1.546e-18	85.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1SY22@1236|Gammaproteobacteria,462Q2@72273|Thiotrichales	72273|Thiotrichales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve_3
SRR25158347_k127_1701575_0	313606.M23134_05784	8.533e-160	511.0	COG2801@1|root,COG2801@2|Bacteria,4NHJD@976|Bacteroidetes,47PPS@768503|Cytophagia	976|Bacteroidetes	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_3
SRR25158347_k127_1701575_1	641112.ACOK01000111_gene1849	1.516e-22	103.0	COG1106@1|root,COG1106@2|Bacteria,1V0QA@1239|Firmicutes,24W4R@186801|Clostridia,3WMYD@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
SRR25158347_k127_1703250_0	1191523.MROS_0276	2.371e-42	168.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158347_k127_1703250_2	379066.GAU_2489	1.596e-18	89.0	COG0636@1|root,COG0636@2|Bacteria,1ZU1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158347_k127_1703250_1	1045858.Bint_2488	2.816e-23	105.0	COG0711@1|root,COG0711@2|Bacteria,2J9EE@203691|Spirochaetes	203691|Spirochaetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158347_k127_1706715_0	306281.AJLK01000113_gene508	8.775e-105	367.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1JI2C@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase
SRR25158347_k127_1706798_0	552398.HMPREF0866_02936	1.389e-08	62.0	COG2197@1|root,COG2197@2|Bacteria,1V0Q0@1239|Firmicutes,249AF@186801|Clostridia,3WM46@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158347_k127_1706798_1	639282.DEFDS_0904	0.0001254	53.0	COG1470@1|root,COG1470@2|Bacteria,2GG9M@200930|Deferribacteres	200930|Deferribacteres	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
SRR25158347_k127_1708514_0	1198232.CYCME_1212	3.186e-36	146.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,461WW@72273|Thiotrichales	72273|Thiotrichales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158347_k127_1709312_0	1121382.JQKG01000001_gene2263	6.854e-65	235.0	COG1501@1|root,COG1501@2|Bacteria,1WJ3Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Gal_mutarotas_2,Glyco_hydro_31
SRR25158347_k127_1709312_1	1395587.P364_0102325	1.755e-10	71.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,4HAQA@91061|Bacilli,26SN4@186822|Paenibacillaceae	91061|Bacilli	P	3-mercaptopyruvate sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158347_k127_1709337_3	1179226.AJXO01000041_gene2027	1.056e-07	53.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	luxC	-	1.2.1.50	ko:K03400	ko02020,ko02024,map02020,map02024	-	R10549	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	LuxC
SRR25158347_k127_1709337_0	283942.IL2402	1.343e-59	220.0	28JNG@1|root,2Z9ES@2|Bacteria,1N32V@1224|Proteobacteria,1S9AH@1236|Gammaproteobacteria,2QGP2@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	pgsW	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1709337_1	283942.IL2401	2.834e-35	139.0	29EG8@1|root,334DW@2|Bacteria,1NFZA@1224|Proteobacteria,1SCN3@1236|Gammaproteobacteria,2QGT7@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Capsule biosynthesis CapC	capC	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
SRR25158347_k127_1709337_2	283942.IL2400	3.827e-33	132.0	COG0769@1|root,COG0769@2|Bacteria,1QYFB@1224|Proteobacteria,1T3Q5@1236|Gammaproteobacteria,2QGQ5@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Mur ligase middle domain	-	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_M
SRR25158347_k127_1709408_0	246194.CHY_1413	1.26e-56	205.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,42JAR@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_1710139_2	630626.EBL_c33680	3.562e-06	53.0	2E7TI@1|root,333ZE@2|Bacteria,1NA5N@1224|Proteobacteria,1SE9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
SRR25158347_k127_1710139_0	314607.KB13_622	2.504e-155	495.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,1KQIZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158347_k127_1710139_1	1469245.JFBG01000083_gene220	1.432e-34	135.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1WWPW@135613|Chromatiales	135613|Chromatiales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158347_k127_1711334_1	1380600.AUYN01000009_gene1396	3.721e-25	106.0	COG0053@1|root,COG0053@2|Bacteria,4NVGY@976|Bacteroidetes,1I5HT@117743|Flavobacteriia	976|Bacteroidetes	P	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	MerC
SRR25158347_k127_1711334_0	1120951.AUBG01000013_gene2670	2.951e-93	314.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1HWTQ@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158347_k127_1711418_0	177437.HRM2_32590	2.855e-05	51.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MIKM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
SRR25158347_k127_1714664_0	290315.Clim_2497	2.564e-104	345.0	COG0427@1|root,COG0427@2|Bacteria,1FDQ1@1090|Chlorobi	1090|Chlorobi	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158347_k127_1716557_0	931276.Cspa_c51360	3.71e-30	129.0	COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,24HHK@186801|Clostridia,36JIJ@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158347_k127_1716557_1	411465.PEPMIC_00097	1.072e-20	96.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,22GKU@1570339|Peptoniphilaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158347_k127_1721462_2	655815.ZPR_0442	6.406e-10	59.0	COG1609@1|root,COG1609@2|Bacteria,4NESN@976|Bacteroidetes,1I1GK@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158347_k127_1721462_0	1121931.AUHG01000016_gene1016	1.15e-190	599.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1HYWH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158347_k127_1721462_1	1121931.AUHG01000016_gene1015	1.594e-25	106.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1HXVN@117743|Flavobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158347_k127_1723988_0	1121904.ARBP01000002_gene7178	2.863e-60	228.0	COG0642@1|root,COG2205@2|Bacteria,4NN26@976|Bacteroidetes,47U6C@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
SRR25158347_k127_1724499_0	673862.BABL1_334	1.534e-35	139.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_1725452_0	983544.Lacal_0869	1.455e-41	161.0	COG0784@1|root,COG1352@1|root,COG2201@1|root,COG4372@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG4372@2|Bacteria,COG5002@2|Bacteria,4PKNJ@976|Bacteroidetes,1IJIK@117743|Flavobacteriia	976|Bacteroidetes	T	protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_1727710_0	1144672.F966_03884	3.11e-16	91.0	COG4249@1|root,COG4249@2|Bacteria,1PHCU@1224|Proteobacteria,1SV06@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158347_k127_1728912_3	1002340.AFCF01000062_gene800	2.04e-16	89.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,34DWB@302485|Phaeobacter	28211|Alphaproteobacteria	P	Sulfatase	pehA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158347_k127_1728912_0	395493.BegalDRAFT_0677	1.085e-96	330.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	carnitine dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158347_k127_1728912_1	1131553.JIBI01000001_gene1469	5.671e-59	221.0	COG1252@1|root,COG1252@2|Bacteria,1PV2J@1224|Proteobacteria,2WB21@28216|Betaproteobacteria,3722V@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_1728912_2	215803.DB30_6384	2.185e-18	96.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SRR25158347_k127_1729782_1	1267211.KI669560_gene1385	1.003e-05	50.0	COG4642@1|root,COG4642@2|Bacteria,4NWQY@976|Bacteroidetes	976|Bacteroidetes	S	MORN repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_1729782_0	525257.HMPREF0204_10292	1.724e-51	192.0	COG4278@1|root,COG4278@2|Bacteria,4NR5D@976|Bacteroidetes,1I30E@117743|Flavobacteriia,3ZPRT@59732|Chryseobacterium	976|Bacteroidetes	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1730670_0	517418.Ctha_0470	5.204e-81	275.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158347_k127_1731106_1	240015.ACP_2845	1.062e-57	208.0	COG4760@1|root,COG4760@2|Bacteria,3Y6G0@57723|Acidobacteria,2JM96@204432|Acidobacteriia	204432|Acidobacteriia	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
SRR25158347_k127_1731106_0	468059.AUHA01000002_gene833	1.855e-90	307.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,1IP32@117747|Sphingobacteriia	976|Bacteroidetes	P	sodium proton antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158347_k127_17322_1	309799.DICTH_1765	3.734e-08	64.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
SRR25158347_k127_17322_0	1116472.MGMO_94c00220	2.028e-103	349.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1XEQF@135618|Methylococcales	135618|Methylococcales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158347_k127_17322_2	756272.Plabr_2036	0.0006651	43.0	COG1454@1|root,COG1454@2|Bacteria,2IY9A@203682|Planctomycetes	203682|Planctomycetes	C	Alcohol dehydrogenase class IV	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158347_k127_1733432_0	439481.Aboo_1450	8.426e-36	145.0	COG0602@1|root,arCOG02173@2157|Archaea,2XUSP@28890|Euryarchaeota,3F2KS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158347_k127_1734265_0	1051646.VITU9109_01222	1.613e-48	177.0	COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,1S44A@1236|Gammaproteobacteria,1XXP0@135623|Vibrionales	135623|Vibrionales	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158347_k127_1734265_1	234267.Acid_5401	1.222e-21	96.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158347_k127_1734794_1	760117.JN27_19035	5.617e-36	150.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
SRR25158347_k127_1734794_0	118797.XP_007449960.1	9.913e-52	189.0	COG0307@1|root,KOG3310@2759|Eukaryota,391FY@33154|Opisthokonta,3BUQU@33208|Metazoa	33208|Metazoa	H	Lumazine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Lum_binding
SRR25158347_k127_1736813_1	243276.TPANIC_0489	9.775e-11	63.0	COG1235@1|root,COG1235@2|Bacteria,2J5C5@203691|Spirochaetes	203691|Spirochaetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_1736813_0	933262.AXAM01000016_gene149	1.903e-65	237.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
SRR25158347_k127_1740355_0	457570.Nther_1643	7.914e-36	144.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158347_k127_1740355_1	445971.ANASTE_01984	3.961e-18	93.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,25V5N@186806|Eubacteriaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
SRR25158347_k127_1741124_1	1121104.AQXH01000004_gene74	4.666e-24	113.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1IT8Y@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158347_k127_1741124_0	382464.ABSI01000013_gene1716	3.207e-44	168.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_1743756_1	1045858.Bint_1145	7.272e-18	87.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	ttg2E	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.5.1.2	ko:K01425,ko:K02066,ko:K03090,ko:K04749,ko:K06378,ko:K07122	ko00220,ko00250,ko00471,ko01100,ko02010,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map02010,map04724,map04727,map04964,map05206,map05230	M00210,M00669,M00670	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko00002,ko01000,ko02000,ko03021	3.A.1.27,3.A.1.27.3	-	-	MEDS,STAS,STAS_2
SRR25158347_k127_1743756_2	1304284.L21TH_1124	0.0002226	53.0	COG1807@1|root,COG1807@2|Bacteria,1V0HR@1239|Firmicutes,24BAC@186801|Clostridia,36NEI@31979|Clostridiaceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158347_k127_1743756_0	1461582.BN1048_00743	2.022e-34	143.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,4GY1Y@90964|Staphylococcaceae	91061|Bacilli	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158347_k127_1747583_1	1268068.PG5_42320	3.891e-40	151.0	2DP11@1|root,33031@2|Bacteria,1RH3P@1224|Proteobacteria	1224|Proteobacteria	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	Tail_tube
SRR25158347_k127_1747583_0	882.DVU_0210	1.901e-72	250.0	COG4386@1|root,COG4386@2|Bacteria,1MXZD@1224|Proteobacteria,42YRB@68525|delta/epsilon subdivisions,2WTP7@28221|Deltaproteobacteria,2MAFC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tail sheath	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158347_k127_1750206_0	1122179.KB890414_gene1831	2.311e-36	150.0	COG0330@1|root,COG0330@2|Bacteria,4NHJA@976|Bacteroidetes	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_1751502_0	1267533.KB906738_gene2403	3.243e-57	213.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HisKA,Response_reg,SpoIIE
SRR25158347_k127_1751502_1	929558.SMGD1_2603	4.48e-42	164.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YMAM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02030,ko:K07679	ko02020,ko05133,map02020,map05133	M00236,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
SRR25158347_k127_1752103_0	1480694.DC28_01695	7.258e-40	156.0	COG0768@1|root,COG0768@2|Bacteria,2J595@203691|Spirochaetes	203691|Spirochaetes	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158347_k127_1752103_1	573413.Spirs_2071	8.485e-23	109.0	COG0772@1|root,COG0772@2|Bacteria,2J62H@203691|Spirochaetes	203691|Spirochaetes	D	Belongs to the SEDS family. MrdB RodA subfamily	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158347_k127_1756989_0	56780.SYN_02890	2.153e-17	93.0	COG3018@1|root,COG3018@2|Bacteria,1R9S8@1224|Proteobacteria,42RI7@68525|delta/epsilon subdivisions,2WP0N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
SRR25158347_k127_1756989_1	237368.SCABRO_00994	2.61e-07	53.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
SRR25158347_k127_1758225_0	1173022.Cri9333_0623	2.944e-33	133.0	COG4422@1|root,COG4422@2|Bacteria,1G1Q2@1117|Cyanobacteria,1HA22@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4422 Bacteriophage protein gp37	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158347_k127_175863_0	545243.BAEV01000029_gene703	6.486e-30	129.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DIS@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_8,sCache_like
SRR25158347_k127_1759153_0	759914.BP951000_1400	2.097e-09	67.0	2DF69@1|root,2ZQMH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1759153_1	1480694.DC28_02620	5.261e-06	52.0	COG1345@1|root,COG1345@2|Bacteria,2J6CW@203691|Spirochaetes	203691|Spirochaetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliD_C,FliD_N
SRR25158347_k127_1763128_1	506534.Rhein_1739	4.056e-27	122.0	COG3420@1|root,COG5492@1|root,COG3420@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,Big_5,DUF3494
SRR25158347_k127_1763128_0	517417.Cpar_1424	6.271e-121	397.0	COG0367@1|root,COG0367@2|Bacteria,1FDEI@1090|Chlorobi	1090|Chlorobi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_1764518_0	555779.Dthio_PD0965	7.116e-44	174.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,430KD@68525|delta/epsilon subdivisions,2WVSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind
SRR25158347_k127_1764518_1	32057.KB217478_gene5311	1.215e-06	54.0	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria,1HNXJ@1161|Nostocales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158347_k127_1770762_0	71421.HI_0407	0.0008791	47.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1Y6XT@135625|Pasteurellales	135625|Pasteurellales	P	High-affinity zinc uptake system membrane protein ZnuB	znuB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158347_k127_1773958_0	1499967.BAYZ01000185_gene4528	2e-65	229.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158347_k127_1773958_1	525898.Sdel_0913	0.0008015	48.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YNJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
SRR25158347_k127_1774385_0	1121904.ARBP01000004_gene929	1.99e-09	63.0	COG0470@1|root,COG0531@1|root,COG0470@2|Bacteria,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47KCI@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
SRR25158347_k127_1774385_1	1122152.AUEI01000006_gene175	6.221e-05	53.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae	91061|Bacilli	M	mechanosensitive ion channel	ykuT	GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004	-	ko:K16052,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3,1.A.23.4	-	-	MS_channel
SRR25158347_k127_1774927_0	1423321.AS29_06690	1.394e-68	236.0	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus	91061|Bacilli	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_1774927_1	929558.SMGD1_0712	7.715e-14	75.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42MFV@68525|delta/epsilon subdivisions,2YM95@29547|Epsilonproteobacteria	2|Bacteria	KT	CHASE2	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,HD,Response_reg
SRR25158347_k127_1775044_0	29581.BW37_05092	0.0	1273.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,4730W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
SRR25158347_k127_1776320_0	1041826.FCOL_03030	2.82e-159	511.0	2BW99@1|root,2Z7PD@2|Bacteria,4PBRA@976|Bacteroidetes,1ICMB@117743|Flavobacteriia,2NT6K@237|Flavobacterium	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1780982_2	616991.JPOO01000003_gene1125	6.6e-28	112.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,1I1JP@117743|Flavobacteriia,23H3K@178469|Arenibacter	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
SRR25158347_k127_1780982_0	616991.JPOO01000003_gene1126	4.431e-100	327.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia,23GSB@178469|Arenibacter	976|Bacteroidetes	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158347_k127_1780982_1	143224.JQMD01000002_gene4314	1.324e-41	156.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1I2WH@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158347_k127_1782500_0	382464.ABSI01000012_gene2128	6.366e-25	108.0	COG0494@1|root,COG0494@2|Bacteria,46ZKB@74201|Verrucomicrobia,2IUIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_1788628_2	1304885.AUEY01000069_gene1434	2.074e-05	47.0	COG2114@1|root,COG2114@2|Bacteria,1Q6BC@1224|Proteobacteria,432SK@68525|delta/epsilon subdivisions,2WXUK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158347_k127_1788628_1	1304885.AUEY01000069_gene1434	1.123e-09	61.0	COG2114@1|root,COG2114@2|Bacteria,1Q6BC@1224|Proteobacteria,432SK@68525|delta/epsilon subdivisions,2WXUK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158347_k127_1788628_0	696281.Desru_2671	5.604e-88	302.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
SRR25158347_k127_1791922_1	690850.Desaf_3612	2.1e-26	113.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria,2MAZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158347_k127_1791922_0	429009.Adeg_0244	8.663e-111	389.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,42END@68295|Thermoanaerobacterales	186801|Clostridia	T	Signal transducing histidine kinase, homodimeric	cheA3	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
SRR25158347_k127_1794591_1	243090.RB5043	3.74e-13	76.0	COG0786@1|root,COG0786@2|Bacteria	2|Bacteria	P	glutamate:sodium symporter activity	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
SRR25158347_k127_1794591_0	525904.Tter_0027	4.069e-169	553.0	COG0821@1|root,COG0821@2|Bacteria,2NNPV@2323|unclassified Bacteria	2|Bacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037	GcpE
SRR25158347_k127_1795548_2	929506.CbC4_0371	2.724e-12	74.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
SRR25158347_k127_1795548_1	1231626.CAHE_0553	3.241e-15	81.0	COG5464@1|root,COG5464@2|Bacteria,4NY1G@976|Bacteroidetes	976|Bacteroidetes	S	Product derived from manual annotation	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SRR25158347_k127_1795548_0	290512.Paes_2385	9.665e-57	207.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_1797807_0	58123.JOFJ01000008_gene436	1.911e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158347_k127_1797807_1	907348.TresaDRAFT_1962	4.794e-10	68.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_1799516_0	637911.AM305_10970	6.45e-06	52.0	COG4886@1|root,COG4886@2|Bacteria,1N30B@1224|Proteobacteria,1SD6B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Leucine Rich repeats (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8
SRR25158347_k127_1803999_1	909663.KI867150_gene1818	2.376e-11	66.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria,2MQ4M@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158347_k127_1803999_0	880073.Calab_2175	6.238e-56	209.0	COG0488@1|root,COG0488@2|Bacteria,2NNPH@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158347_k127_1808004_4	397291.C804_03187	4.257e-07	52.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,27N1X@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_1808004_2	545695.TREAZ_1686	2.169e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_2,TPR_7,TPR_8
SRR25158347_k127_1808004_0	755732.Fluta_3902	4.066e-22	106.0	COG0823@1|root,COG2885@1|root,COG3063@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3063@2|Bacteria,4NE6G@976|Bacteroidetes,1INKT@117743|Flavobacteriia,2PA4S@246874|Cryomorphaceae	976|Bacteroidetes	MNU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
SRR25158347_k127_1808004_1	1313301.AUGC01000005_gene215	2e-13	76.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
SRR25158347_k127_1808004_3	459495.SPLC1_S550460	1.215e-09	65.0	COG0834@1|root,COG3409@1|root,COG0834@2|Bacteria,COG3409@2|Bacteria,1G48M@1117|Cyanobacteria,1H7C7@1150|Oscillatoriales	1117|Cyanobacteria	EMT	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SBP_bac_3
SRR25158347_k127_1809272_0	880073.Calab_3323	1.021e-17	96.0	COG1538@1|root,COG1538@2|Bacteria,2NPI8@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158347_k127_1809668_1	1165841.SULAR_03697	1.085e-62	219.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
SRR25158347_k127_1809668_0	1165841.SULAR_03692	4.02e-263	820.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM Alpha amylase, catalytic	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158347_k127_1810345_1	1120951.AUBG01000002_gene1481	2.415e-09	60.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia	976|Bacteroidetes	K	AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158347_k127_1810345_0	555500.I215_02778	4.048e-73	250.0	COG0664@1|root,COG0664@2|Bacteria,4NM5E@976|Bacteroidetes,1I1AQ@117743|Flavobacteriia	976|Bacteroidetes	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_181075_0	485917.Phep_2111	4.509e-41	166.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1INUH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
SRR25158347_k127_1811547_0	1121287.AUMU01000008_gene2063	2.268e-11	68.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,1HXJI@117743|Flavobacteriia,3ZNJT@59732|Chryseobacterium	976|Bacteroidetes	P	Putative metal-binding domain of cation transport ATPase	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
SRR25158347_k127_181334_0	1173027.Mic7113_3377	1.218e-129	424.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1H9WN@1150|Oscillatoriales	1117|Cyanobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_1819889_0	1121918.ARWE01000001_gene2213	9.965e-66	229.0	COG0075@1|root,COG3420@1|root,COG0075@2|Bacteria,COG3420@2|Bacteria,1QY9B@1224|Proteobacteria,431FJ@68525|delta/epsilon subdivisions,2WWRJ@28221|Deltaproteobacteria	1224|Proteobacteria	P	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
SRR25158347_k127_1819889_1	349521.HCH_00957	1.238e-50	183.0	COG1502@1|root,COG1502@2|Bacteria,1RG9Z@1224|Proteobacteria,1S45X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158347_k127_1819889_2	264462.Bd3206	2.173e-44	169.0	COG0400@1|root,COG0400@2|Bacteria,1N0UF@1224|Proteobacteria,42TUA@68525|delta/epsilon subdivisions,2MT5K@213481|Bdellovibrionales,2WQDY@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Serine hydrolase (FSH1)	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158347_k127_1822328_0	643473.KB235930_gene1132	7.64e-05	51.0	29GGR@1|root,303EG@2|Bacteria,1G6DD@1117|Cyanobacteria,1HMDV@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1823804_2	1394178.AWOO02000004_gene2445	2.749e-13	73.0	COG1309@1|root,COG1309@2|Bacteria,2GJZT@201174|Actinobacteria,4EK61@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_1823804_1	497964.CfE428DRAFT_2363	5.807e-34	141.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1823804_0	225937.HP15_3636	1.227e-135	441.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,464HZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_1829759_0	880071.Fleli_1610	9.087e-101	342.0	COG1752@1|root,COG1752@2|Bacteria,4NPBQ@976|Bacteroidetes,47QP5@768503|Cytophagia	976|Bacteroidetes	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158347_k127_183208_1	944480.ATUV01000001_gene1537	8.809e-31	128.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	GGACT
SRR25158347_k127_183208_0	269799.Gmet_1507	1.535e-44	182.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158347_k127_1834691_1	1168289.AJKI01000040_gene3219	6.844e-13	68.0	COG5002@1|root,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,2FX4K@200643|Bacteroidia,3XJ3F@558415|Marinilabiliaceae	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,HisKA_7TM,Hpt,PAS,PAS_3,PAS_8,PAS_9,Response_reg
SRR25158347_k127_1834691_0	293826.Amet_4420	9.876e-55	202.0	COG2199@1|root,COG3706@2|Bacteria,1TR5R@1239|Firmicutes,24E9M@186801|Clostridia,36FFC@31979|Clostridiaceae	186801|Clostridia	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
SRR25158347_k127_1834700_0	163908.KB235896_gene3556	1.71e-120	396.0	COG0515@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1GQ9E@1117|Cyanobacteria,1HIP0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_183599_0	1280380.KR100_01405	2.099e-79	276.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria,1GZUE@1129|Synechococcus	1117|Cyanobacteria	H	Phosphomethylpyrimidine kinase	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
SRR25158347_k127_1839500_0	880073.Calab_2105	3.257e-109	374.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249,ko:K20035	ko00071,ko00280,ko00410,ko00640,ko00650,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map00920,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R11130	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246,RC03363	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SRR25158347_k127_1839670_0	761193.Runsl_0915	1.642e-45	169.0	COG4270@1|root,COG4270@2|Bacteria,4NQAY@976|Bacteroidetes,47RIE@768503|Cytophagia	976|Bacteroidetes	S	COGs COG4270 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158347_k127_1839670_2	795359.TOPB45_0249	4.904e-06	51.0	COG1032@1|root,COG1032@2|Bacteria,2GI0E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158347_k127_1839670_1	41431.PCC8801_3784	1.888e-21	97.0	COG5470@1|root,COG5470@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158347_k127_1840911_1	10160.XP_004639649.1	0.0006809	48.0	COG0666@1|root,KOG4582@1|root,KOG0504@2759|Eukaryota,KOG4582@2759|Eukaryota,38G8W@33154|Opisthokonta,3B9Q8@33208|Metazoa,3CVHS@33213|Bilateria,484P8@7711|Chordata,48YWR@7742|Vertebrata,3JCYH@40674|Mammalia,35PHJ@314146|Euarchontoglires,4Q3M2@9989|Rodentia	33208|Metazoa	O	Notch signaling pathway	MIB2	GO:0000151,GO:0000209,GO:0000768,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0006464,GO:0006807,GO:0006949,GO:0007520,GO:0008092,GO:0008150,GO:0008152,GO:0008270,GO:0009653,GO:0009987,GO:0012505,GO:0014902,GO:0016567,GO:0016740,GO:0017022,GO:0019538,GO:0019725,GO:0019787,GO:0030016,GO:0030017,GO:0030018,GO:0030154,GO:0031410,GO:0031430,GO:0031672,GO:0031674,GO:0031982,GO:0032027,GO:0032033,GO:0032036,GO:0032038,GO:0032446,GO:0032502,GO:0032991,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045159,GO:0046716,GO:0046872,GO:0046914,GO:0048646,GO:0048856,GO:0048869,GO:0051146,GO:0060249,GO:0061061,GO:0061630,GO:0061659,GO:0065007,GO:0065008,GO:0070647,GO:0071704,GO:0097708,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564,GO:1902494,GO:1990234	2.3.2.27	ko:K10645	-	-	-	-	ko00000,ko01000,ko04121	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,MIB_HERC2,ZZ,zf-C3HC4_3
SRR25158347_k127_1840911_0	1391646.AVSU01000037_gene2068	5.539e-33	141.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S,N6_Mtase
SRR25158347_k127_1845345_0	157072.XP_008875464.1	5.088e-138	445.0	COG1866@1|root,2QQI5@2759|Eukaryota	2759|Eukaryota	C	phosphoenolpyruvate carboxykinase (ATP) activity	PCK1	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006083,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015976,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019318,GO:0019319,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158347_k127_1845345_1	313606.M23134_07912	7.206e-13	70.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,47N1D@768503|Cytophagia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
SRR25158347_k127_1850668_0	598659.NAMH_1438	3.362e-84	299.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_186040_0	1319815.HMPREF0202_00212	8.529e-164	523.0	COG0466@1|root,COG0466@2|Bacteria,3789S@32066|Fusobacteria	32066|Fusobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158347_k127_1863155_1	1304885.AUEY01000001_gene3151	1.003e-09	61.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,42P1A@68525|delta/epsilon subdivisions,2WM73@28221|Deltaproteobacteria,2MIVM@213118|Desulfobacterales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158347_k127_1863155_0	331113.SNE_A17690	8.904e-82	296.0	COG1640@1|root,COG1640@2|Bacteria,2JFE9@204428|Chlamydiae	204428|Chlamydiae	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158347_k127_1865884_0	536232.CLM_4031	2.618e-98	341.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,36F91@31979|Clostridiaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158347_k127_1869180_0	525368.HMPREF0591_5721	6.406e-16	80.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,232QB@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD12	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_1872083_0	1128398.Curi_c23140	4.986e-30	123.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia,268R1@186813|unclassified Clostridiales	186801|Clostridia	K	CarD-like/TRCF domain	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158347_k127_1873519_0	1173028.ANKO01000127_gene4122	6.742e-183	590.0	COG0515@1|root,COG0642@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,1GHS3@1117|Cyanobacteria,1HF2M@1150|Oscillatoriales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase
SRR25158347_k127_1881602_0	1415778.JQMM01000001_gene454	1.168e-52	192.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1J5ND@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	IV02_25675	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158347_k127_1881602_1	247490.KSU1_C0452	6.524e-38	164.0	COG1629@1|root,COG4771@2|Bacteria,2J2B7@203682|Planctomycetes	203682|Planctomycetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_1885974_0	28229.ND2E_1821	4.29e-21	97.0	COG2204@1|root,COG2204@2|Bacteria,1NHJE@1224|Proteobacteria,1SIIQ@1236|Gammaproteobacteria,2Q8C4@267889|Colwelliaceae	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_1885974_1	28229.ND2E_1822	3.071e-10	61.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,2Q7UY@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9
SRR25158347_k127_1887076_1	641107.CDLVIII_5752	2.182e-16	83.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36HH1@31979|Clostridiaceae	186801|Clostridia	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
SRR25158347_k127_1887076_0	439235.Dalk_3928	1.415e-43	164.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WPM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	cheW36H	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158347_k127_1887484_1	1220589.CD32_06575	0.0004474	52.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,3IWTY@400634|Lysinibacillus	91061|Bacilli	KT	Phosphoserine phosphatase	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	RsbU_N,SpoIIE
SRR25158347_k127_1887484_0	858215.Thexy_0714	1.053e-55	198.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,42EZN@68295|Thermoanaerobacterales	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158347_k127_1887618_1	985255.APHJ01000026_gene2383	6.689e-48	180.0	COG0642@1|root,COG2205@2|Bacteria,4NG6V@976|Bacteroidetes,1HWTT@117743|Flavobacteriia,2P5YN@244698|Gillisia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Response_reg
SRR25158347_k127_1887618_0	876044.IMCC3088_1311	1.045e-101	340.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,1J7RY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_1890823_0	373994.Riv7116_0922	4.644e-95	329.0	COG1075@1|root,COG1075@2|Bacteria,1GIQY@1117|Cyanobacteria,1HP99@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1893297_1	349521.HCH_00727	8.423e-62	220.0	292MS@1|root,2ZQ5N@2|Bacteria,1N3H9@1224|Proteobacteria,1SGA5@1236|Gammaproteobacteria,1XQTS@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1893297_0	880070.Cycma_1212	1.51e-110	372.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084,ko:K06196	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.2	-	-	DsbD,DsbD_2,Thioredoxin_7
SRR25158347_k127_1894316_1	1304885.AUEY01000012_gene1799	1.05e-17	96.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158347_k127_1894316_0	1123371.ATXH01000004_gene1740	5.157e-27	115.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158347_k127_1901228_0	565034.BHWA1_00463	2.321e-22	108.0	COG0840@1|root,COG0840@2|Bacteria,2J7VQ@203691|Spirochaetes	203691|Spirochaetes	NT	methyl-accepting chemotaxis protein	mcp-4	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
SRR25158347_k127_1901548_1	1485545.JQLW01000013_gene1823	1.093e-32	129.0	COG2411@1|root,COG2411@2|Bacteria,1NYDV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1901548_0	1242864.D187_004195	2.479e-88	300.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2WK1W@28221|Deltaproteobacteria,2YYDA@29|Myxococcales	28221|Deltaproteobacteria	K	Sir2 family	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158347_k127_190459_0	1123288.SOV_2c07090	3.552e-21	96.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	1239|Firmicutes	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,NERD,Pkinase,TPR_2,TPR_8
SRR25158347_k127_1905973_1	1123288.SOV_6c02530	6.561e-28	117.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H2FT@909932|Negativicutes	1239|Firmicutes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158347_k127_1905973_0	868864.Dester_1433	7.7e-30	130.0	COG0739@1|root,COG0739@2|Bacteria,2G3Y3@200783|Aquificae	200783|Aquificae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_1908011_0	1443122.Z958_01495	0.0006833	51.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36GR1@31979|Clostridiaceae	186801|Clostridia	T	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
SRR25158347_k127_1912980_0	1469245.JFBG01000060_gene2390	5.385e-21	106.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1RCVP@1224|Proteobacteria	1224|Proteobacteria	O	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SRR25158347_k127_1916682_0	909663.KI867150_gene863	2.203e-207	661.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2MQ64@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SRR25158347_k127_1917626_0	1301100.HG529235_gene7312	1.273e-54	197.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,36F63@31979|Clostridiaceae	186801|Clostridia	C	FMN-dependent	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
SRR25158347_k127_1917893_2	196162.Noca_2833	1.973e-06	53.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158347_k127_1917893_1	1121121.KB894321_gene329	3.418e-19	100.0	COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,26R26@186822|Paenibacillaceae	91061|Bacilli	V	Beta-lactamase class C and other penicillin binding proteins	pbpX	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,SLH
SRR25158347_k127_1917893_0	1064535.MELS_1627	9.198e-26	109.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4H3CU@909932|Negativicutes	909932|Negativicutes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158347_k127_1921728_0	1304284.L21TH_1366	4.884e-18	90.0	COG0419@1|root,COG0419@2|Bacteria,1UQNY@1239|Firmicutes,24UHC@186801|Clostridia	186801|Clostridia	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_27
SRR25158347_k127_1924600_0	391038.Bphy_1869	6.472e-13	77.0	COG3778@1|root,COG3778@2|Bacteria,1N3CF@1224|Proteobacteria,2VWSB@28216|Betaproteobacteria,1KHGJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterised protein conserved in bacteria (DUF2313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
SRR25158347_k127_1924639_1	945713.IALB_0018	1.388e-17	87.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158347_k127_1924639_0	1469607.KK073768_gene4378	1.416e-112	375.0	COG1473@1|root,COG1473@2|Bacteria,1G01G@1117|Cyanobacteria,1HJSV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Peptidase family M20 M25 M40	ama	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158347_k127_1924639_2	13249.RPRC013400-PA	6.591e-12	76.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3BESA@33208|Metazoa,3CWK8@33213|Bilateria,41XC0@6656|Arthropoda,3SFQN@50557|Insecta	33208|Metazoa	T	cAMP-dependent protein kinase regulator activity. It is involved in the biological process described with regulation of protein phosphorylation	PRKAR2B	GO:0000086,GO:0000166,GO:0000278,GO:0000902,GO:0000904,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006082,GO:0006469,GO:0006629,GO:0006631,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007399,GO:0007409,GO:0007411,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007622,GO:0007623,GO:0007626,GO:0008150,GO:0008152,GO:0008603,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010389,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019752,GO:0019866,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022402,GO:0022406,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030104,GO:0030154,GO:0030182,GO:0030234,GO:0030291,GO:0030315,GO:0030425,GO:0030534,GO:0030551,GO:0030552,GO:0030554,GO:0031090,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0031966,GO:0031967,GO:0031975,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032870,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0036477,GO:0040011,GO:0042060,GO:0042220,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043025,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043197,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043279,GO:0043434,GO:0043436,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044297,GO:0044309,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0044853,GO:0045121,GO:0045202,GO:0045471,GO:0045475,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046677,GO:0046983,GO:0048148,GO:0048149,GO:0048468,GO:0048471,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051640,GO:0051641,GO:0051716,GO:0051726,GO:0060255,GO:0060271,GO:0060281,GO:0060282,GO:0060284,GO:0060359,GO:0061564,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072347,GO:0080090,GO:0090068,GO:0097159,GO:0097305,GO:0097332,GO:0097338,GO:0097367,GO:0097447,GO:0097458,GO:0097485,GO:0097546,GO:0097711,GO:0098589,GO:0098590,GO:0098772,GO:0098794,GO:0098805,GO:0098857,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0140056,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901990,GO:1902494,GO:1902749,GO:1902911,GO:1903047,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRR25158347_k127_1927703_0	1121481.AUAS01000003_gene4043	5.374e-172	554.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47M8Q@768503|Cytophagia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158347_k127_1927703_1	237368.SCABRO_02000	1.805e-28	117.0	COG0713@1|root,COG0713@2|Bacteria,2J0GU@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158347_k127_1927703_2	1501269.EW15_0246	2.831e-06	53.0	COG0839@1|root,COG0839@2|Bacteria,1G2WH@1117|Cyanobacteria,1MM6P@1212|Prochloraceae	1117|Cyanobacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
SRR25158347_k127_1928499_0	1297742.A176_03032	1.312e-40	165.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria,2YZZ6@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR25158347_k127_1932546_0	565034.BHWA1_00916	1.241e-71	246.0	COG4786@1|root,COG4786@2|Bacteria,2J57D@203691|Spirochaetes	203691|Spirochaetes	N	flagellar basal-body rod protein FlgG	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_1933563_0	1408321.JNJD01000006_gene849	3.059e-34	148.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,27J34@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158347_k127_1937239_2	1382358.JHVN01000016_gene523	1.632e-07	53.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,21WBT@150247|Anoxybacillus	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158347_k127_1937239_1	243090.RB7662	1.1e-55	200.0	COG0131@1|root,COG0131@2|Bacteria,2IYU4@203682|Planctomycetes	203682|Planctomycetes	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158347_k127_1937239_0	882.DVU_0723	3.316e-60	211.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2WJD1@28221|Deltaproteobacteria,2M9TR@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp,Epimerase
SRR25158347_k127_1937911_0	1220582.RRU01S_16_01230	1.872e-20	107.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,4BAQT@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	NAD-specific glutamate dehydrogenase	gdhB	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158347_k127_1938959_2	1158338.JNLJ01000001_gene667	4.219e-27	115.0	COG0801@1|root,COG0801@2|Bacteria,2G4AJ@200783|Aquificae	200783|Aquificae	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158347_k127_1938959_1	688269.Theth_0808	1.898e-78	270.0	COG0413@1|root,COG0413@2|Bacteria,2GCQP@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158347_k127_1938959_0	555088.DealDRAFT_1878	1.547e-185	588.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes	1239|Firmicutes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158347_k127_1947331_0	1121897.AUGO01000007_gene339	2.235e-40	158.0	2EETV@1|root,338MC@2|Bacteria,4NWTT@976|Bacteroidetes,1IA3C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1947608_1	1033734.CAET01000018_gene714	1.947e-49	186.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158347_k127_1947608_0	1321778.HMPREF1982_04283	1.469e-71	256.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,268MH@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_1949183_0	1540257.JQMW01000009_gene2977	2.101e-50	191.0	COG3599@1|root,COG3599@2|Bacteria,1TRNH@1239|Firmicutes,25EYI@186801|Clostridia,36K7J@31979|Clostridiaceae	186801|Clostridia	D	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR25158347_k127_1949183_1	313606.M23134_03016	1.257e-18	87.0	COG0175@1|root,COG0175@2|Bacteria,4NDWR@976|Bacteroidetes,47U4F@768503|Cytophagia	976|Bacteroidetes	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	ko:K19170	-	-	-	-	ko00000,ko02048	-	-	-	PAPS_reduct
SRR25158347_k127_1952714_0	573413.Spirs_2028	1.058e-112	372.0	COG0532@1|root,COG0532@2|Bacteria,2J692@203691|Spirochaetes	203691|Spirochaetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158347_k127_1952714_1	382245.ASA_1011	3.443e-15	79.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1Y4GP@135624|Aeromonadales	135624|Aeromonadales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158347_k127_1953192_0	756067.MicvaDRAFT_3583	6.986e-145	483.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
SRR25158347_k127_1955087_0	525897.Dbac_2187	2.464e-96	334.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
SRR25158347_k127_1957045_0	1307761.L21SP2_0140	8.485e-23	107.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_1957045_1	521674.Plim_1229	1.824e-09	65.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158347_k127_196154_0	243232.MJ_1345	8.429e-05	54.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,23R7V@183939|Methanococci	183939|Methanococci	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
SRR25158347_k127_1963274_1	871585.BDGL_002737	1.934e-05	48.0	COG3791@1|root,COG3791@2|Bacteria,1REMP@1224|Proteobacteria,1S3AW@1236|Gammaproteobacteria,3NT8K@468|Moraxellaceae	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158347_k127_1964560_0	517418.Ctha_0944	1.163e-89	304.0	COG1336@1|root,COG1336@2|Bacteria,1FEAC@1090|Chlorobi	1090|Chlorobi	L	TIGRFAM CRISPR-associated RAMP protein, Cmr4 family	-	-	-	ko:K09000	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
SRR25158347_k127_1964560_1	517418.Ctha_0943	6.143e-07	52.0	COG3337@1|root,COG3337@2|Bacteria	2|Bacteria	L	CRISPR-associated protein (Cas_Cmr5)	-	-	-	ko:K19141	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cmr5
SRR25158347_k127_1967200_6	568816.Acin_1226	8.464e-05	55.0	2F42X@1|root,33WUI@2|Bacteria,1W5SK@1239|Firmicutes,4H8QR@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1967200_1	761193.Runsl_0355	3.407e-53	216.0	COG3941@1|root,COG3941@2|Bacteria,4PP2D@976|Bacteroidetes,47YF4@768503|Cytophagia	976|Bacteroidetes	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1967200_5	237368.SCABRO_02736	3.551e-08	65.0	COG1749@1|root,COG1749@2|Bacteria,2IYJT@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_1967200_7	1499685.CCFJ01000055_gene1936	0.0008457	51.0	2DCCD@1|root,2ZDNK@2|Bacteria,1V1YS@1239|Firmicutes,4IA28@91061|Bacilli,1ZIHA@1386|Bacillus	91061|Bacilli	S	Phage minor capsid protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Phage_min_cap2
SRR25158347_k127_1967200_4	1408428.JNJP01000148_gene976	1.821e-12	79.0	2C377@1|root,2Z7II@2|Bacteria,1NNYY@1224|Proteobacteria,42YAN@68525|delta/epsilon subdivisions,2WUGQ@28221|Deltaproteobacteria,2MA6G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	P22 coat protein - gene protein 5	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
SRR25158347_k127_1967200_2	1150626.PHAMO_80073	1.599e-27	128.0	2BF3Y@1|root,315AZ@2|Bacteria,1NCT0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4055
SRR25158347_k127_1967200_0	1313421.JHBV01000006_gene322	2.564e-57	207.0	COG0338@1|root,COG0338@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158347_k127_1967223_0	290402.Cbei_4485	3.638e-70	247.0	COG4191@1|root,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,249I4@186801|Clostridia,36GPP@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg,dCache_1
SRR25158347_k127_1967223_1	290402.Cbei_4484	3.4e-16	81.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Pkinase,PocR,Response_reg
SRR25158347_k127_1969186_1	1121875.KB907549_gene1764	3.595e-06	56.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	inlA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DUF285,LRR_4,LRR_6,Lectin_legB,Strep_his_triad
SRR25158347_k127_1969186_0	1265503.KB905164_gene1938	5.92e-31	138.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
SRR25158347_k127_1970120_1	909663.KI867150_gene359	7.339e-46	171.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MQBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158347_k127_1970120_2	1195236.CTER_0151	1.979e-34	141.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158347_k127_1970120_0	1476973.JMMB01000007_gene218	2.834e-71	256.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,25QGZ@186804|Peptostreptococcaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158347_k127_1971394_0	1449126.JQKL01000002_gene1589	1.375e-45	179.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_1971826_1	1448389.BAVQ01000003_gene3476	1.469e-05	56.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria	201174|Actinobacteria	S	phosphatidylinositol metabolic process	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRR25158347_k127_1971826_0	1047013.AQSP01000142_gene195	4.714e-51	186.0	COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158347_k127_1972060_0	1423724.BAMM01000002_gene443	7.189e-44	169.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_1972157_0	1201290.M902_2020	1.918e-18	97.0	COG3210@1|root,COG3210@2|Bacteria,1NGFP@1224|Proteobacteria,43EIP@68525|delta/epsilon subdivisions,2X8HE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Chaperone of endosialidase	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Peptidase_S74
SRR25158347_k127_1977671_0	639282.DEFDS_0507	3.102e-253	797.0	COG0525@1|root,COG0525@2|Bacteria,2GF6T@200930|Deferribacteres	200930|Deferribacteres	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158347_k127_197927_0	648996.Theam_1095	1.219e-95	322.0	COG0115@1|root,COG0115@2|Bacteria,2G3W3@200783|Aquificae	200783|Aquificae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158347_k127_1979719_0	1185876.BN8_03145	0.0	1112.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158347_k127_1981516_0	933262.AXAM01000068_gene2771	9.072e-71	255.0	COG0438@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0859@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria,2MNV6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158347_k127_1981727_0	56110.Oscil6304_2815	8.022e-31	136.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
SRR25158347_k127_1982908_1	941770.GL622181_gene770	0.0009642	46.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae	91061|Bacilli	E	succinyl-diaminopimelate desuccinylase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158347_k127_1982908_0	1173027.Mic7113_1525	5.413e-77	262.0	COG0042@1|root,COG0042@2|Bacteria,1G0ME@1117|Cyanobacteria,1H79P@1150|Oscillatoriales	1117|Cyanobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158347_k127_1985345_0	1869.MB27_39480	3.334e-70	250.0	COG2201@1|root,COG2201@2|Bacteria,2GMBC@201174|Actinobacteria,4D8WI@85008|Micromonosporales	201174|Actinobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158347_k127_1985345_1	118168.MC7420_4799	2.987e-58	207.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Bac_globin,GAF_2,HAMP,MCPsignal,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158347_k127_1989185_0	526224.Bmur_0609	1.54e-33	143.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2J6RF@203691|Spirochaetes	203691|Spirochaetes	M	LysM domain M23 M37 peptidase domain protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR25158347_k127_1989185_1	1122217.KB899571_gene1122	7.071e-15	76.0	COG2217@1|root,COG2217@2|Bacteria,1UD4A@1239|Firmicutes,4H4KM@909932|Negativicutes	909932|Negativicutes	P	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
SRR25158347_k127_1989830_1	1123514.KB905899_gene442	2.997e-92	308.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RMXA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fad linked oxidase	dprE1	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
SRR25158347_k127_1989830_0	880073.Calab_0773	4.637e-139	449.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
SRR25158347_k127_1990173_0	1157490.EL26_18170	1.154e-42	166.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,278DG@186823|Alicyclobacillaceae	91061|Bacilli	T	Protein phosphatase 2C	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158347_k127_1991087_0	237368.SCABRO_01589	4.122e-08	63.0	COG0457@1|root,COG0457@2|Bacteria,2J2H9@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
SRR25158347_k127_1991510_0	402777.KB235904_gene4100	2.845e-78	277.0	COG0515@1|root,COG2203@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_1991510_2	323259.Mhun_3103	1.037e-08	59.0	arCOG01426@1|root,arCOG01426@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_1991510_3	1414720.CBYM010000007_gene1152	4.131e-06	53.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,36KNM@31979|Clostridiaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
SRR25158347_k127_1991510_1	56110.Oscil6304_2815	7.34e-35	139.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
SRR25158347_k127_1992157_1	744872.Spica_2507	2.609e-05	49.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158347_k127_1992157_0	1267534.KB906756_gene681	4.748e-28	126.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,3Y56X@57723|Acidobacteria,2JM0P@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
SRR25158347_k127_1993070_2	985255.APHJ01000019_gene734	2.285e-21	94.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2P6Z2@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158347_k127_1993070_1	1121931.AUHG01000016_gene1118	7.865e-66	227.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158347_k127_1993070_0	865937.Gilli_0639	1.187e-163	519.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1I0IH@117743|Flavobacteriia,2P5VX@244698|Gillisia	976|Bacteroidetes	G	Aldose 1-epimerase	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158347_k127_1993193_1	1279009.ADICEAN_00073	3.473e-93	309.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
SRR25158347_k127_1993193_0	497964.CfE428DRAFT_3990	1.744e-321	995.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia	74201|Verrucomicrobia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158347_k127_1993193_2	497964.CfE428DRAFT_3991	6.524e-57	206.0	2CAZH@1|root,2Z7RU@2|Bacteria,46SY1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158347_k127_1993232_0	1173028.ANKO01000017_gene82	5.249e-96	327.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_1994611_0	1396418.BATQ01000137_gene3897	9.985e-24	104.0	COG1595@1|root,COG1595@2|Bacteria,46WAZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_1994611_1	1443665.JACA01000007_gene232	1.101e-09	68.0	COG3103@1|root,COG3103@2|Bacteria,4PMRF@976|Bacteroidetes,1IJXB@117743|Flavobacteriia	976|Bacteroidetes	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158347_k127_1994895_0	1137799.GZ78_01890	2.697e-89	299.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria,1XICS@135619|Oceanospirillales	135619|Oceanospirillales	Q	( 3 oxidation state) methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158347_k127_1994895_1	1122225.AULQ01000004_gene2019	9.957e-31	124.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,1HY5E@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
SRR25158347_k127_1996357_1	1235799.C818_02597	0.0008862	50.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,27ID6@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_1996357_0	445972.ANACOL_01809	1.942e-10	63.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
SRR25158347_k127_1998585_0	204536.SULAZ_1380	8.036e-16	89.0	COG0815@1|root,COG0815@2|Bacteria,2G4WS@200783|Aquificae	200783|Aquificae	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158347_k127_1998585_1	391625.PPSIR1_34932	1.693e-07	59.0	COG2845@1|root,COG2845@2|Bacteria,1R4X7@1224|Proteobacteria,42PSW@68525|delta/epsilon subdivisions,2X5KJ@28221|Deltaproteobacteria,2Z066@29|Myxococcales	28221|Deltaproteobacteria	S	GDSL-like lipase acylhydrolase	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
SRR25158347_k127_199943_0	1121423.JONT01000026_gene903	1.063e-144	470.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRR25158347_k127_2000766_0	1121946.AUAX01000002_gene18	3.32e-57	225.0	COG4928@1|root,COG4928@2|Bacteria,2IB3U@201174|Actinobacteria,4DEUM@85008|Micromonosporales	201174|Actinobacteria	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase,WD40
SRR25158347_k127_2000766_1	10224.XP_006820279.1	3.542e-20	106.0	COG0666@1|root,KOG0502@2759|Eukaryota,39FDA@33154|Opisthokonta,3BGSV@33208|Metazoa,3CS2Z@33213|Bilateria	33208|Metazoa	J	nerve growth factor signaling pathway	KIDINS220	GO:0000186,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005829,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007399,GO:0008150,GO:0009719,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0019207,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030165,GO:0030234,GO:0031323,GO:0031325,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031410,GO:0031982,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0033674,GO:0038179,GO:0038180,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043549,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0065007,GO:0065009,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071900,GO:0071902,GO:0080090,GO:0097708,GO:0098772,GO:0120035,GO:1902531,GO:1902533,GO:1990089,GO:1990090,GO:2000026	-	ko:K12460	ko04722,map04722	-	-	-	ko00000,ko00001	-	-	-	Ank,Ank_2,Ank_4,Ank_5,KAP_NTPase
SRR25158347_k127_2001389_0	1410622.JNKY01000001_gene1325	7.028e-06	58.0	COG3209@1|root,COG3209@2|Bacteria,1UPJF@1239|Firmicutes,25HI7@186801|Clostridia,27UMV@186928|unclassified Lachnospiraceae	186801|Clostridia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2001463_0	869213.JCM21142_3838	1.017e-64	237.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TK7@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_2003386_0	215803.DB30_7109	9.355e-97	328.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158347_k127_2003386_1	645991.Sgly_0651	1.395e-06	58.0	COG1589@1|root,COG1589@2|Bacteria,1VEMW@1239|Firmicutes,24I0V@186801|Clostridia,261R8@186807|Peptococcaceae	186801|Clostridia	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158347_k127_2004843_0	658187.LDG_6986	1.51e-14	87.0	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,1SNAF@1236|Gammaproteobacteria,1JE2M@118969|Legionellales	118969|Legionellales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2008482_2	1037409.BJ6T_37240	8.978e-34	136.0	COG3239@1|root,COG3239@2|Bacteria,1NIZS@1224|Proteobacteria,2UNUT@28211|Alphaproteobacteria,3K2D7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158347_k127_2008482_1	349163.Acry_1480	3.16e-56	204.0	COG4122@1|root,COG4122@2|Bacteria,1RF3H@1224|Proteobacteria,2U84F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,TylF
SRR25158347_k127_2008482_0	1267535.KB906767_gene2544	1.15e-62	226.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
SRR25158347_k127_2008482_3	1033737.CAEV01000089_gene215	1.469e-06	53.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,36IDY@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158347_k127_2009689_0	1206741.BAFX01000196_gene3592	2.511e-47	183.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4FWTZ@85025|Nocardiaceae	201174|Actinobacteria	I	Fatty acid desaturase	desA3	GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158347_k127_2010519_0	1123274.KB899412_gene1471	2.226e-71	256.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,2J6N2@203691|Spirochaetes	203691|Spirochaetes	NT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158347_k127_2012447_0	1519464.HY22_02150	3.833e-08	54.0	COG0423@1|root,COG0423@2|Bacteria,1FDA0@1090|Chlorobi	1090|Chlorobi	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158347_k127_201299_0	1111134.HMPREF1253_1383	6.393e-17	87.0	2DN8P@1|root,32W46@2|Bacteria,1VXJS@1239|Firmicutes,24VWN@186801|Clostridia	186801|Clostridia	S	Bacterial inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
SRR25158347_k127_2015659_0	236814.IX39_19480	1.427e-06	59.0	COG3103@1|root,COG3103@2|Bacteria,4NRNZ@976|Bacteroidetes,1I3T7@117743|Flavobacteriia,3ZQD7@59732|Chryseobacterium	976|Bacteroidetes	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158347_k127_2015659_1	1192034.CAP_4849	3.68e-05	49.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,43DV7@68525|delta/epsilon subdivisions,2WYYQ@28221|Deltaproteobacteria,2Z0Y3@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
SRR25158347_k127_2017787_0	596153.Alide_3602	4.233e-07	61.0	COG2849@1|root,COG2849@2|Bacteria,1P4KC@1224|Proteobacteria	1224|Proteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2020390_0	2074.JNYD01000010_gene998	2.326e-58	214.0	COG1063@1|root,COG1063@2|Bacteria,2GNFX@201174|Actinobacteria,4E2BI@85010|Pseudonocardiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_2020390_1	999541.bgla_2g22040	1.554e-05	54.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,2VJR8@28216|Betaproteobacteria,1K60Y@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158347_k127_2026429_3	945713.IALB_0475	4.044e-10	64.0	COG0597@1|root,COG0597@2|Bacteria	2|Bacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158347_k127_2026429_0	391615.ABSJ01000027_gene160	1.769e-48	184.0	COG0596@1|root,COG0596@2|Bacteria,1R4PH@1224|Proteobacteria,1S03W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,adh_short
SRR25158347_k127_2026429_1	204669.Acid345_2946	6.066e-32	142.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,3Y56X@57723|Acidobacteria,2JM0P@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
SRR25158347_k127_2026678_1	555088.DealDRAFT_2538	1.568e-24	104.0	COG1960@1|root,COG1960@2|Bacteria,1V03D@1239|Firmicutes,24A8N@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158347_k127_2026678_0	1128427.KB904821_gene1777	2.08e-29	122.0	COG0639@1|root,COG0639@2|Bacteria,1GR5K@1117|Cyanobacteria,1HB1P@1150|Oscillatoriales	1117|Cyanobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
SRR25158347_k127_2026678_2	1249480.B649_09585	3.285e-15	78.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158347_k127_2026678_3	944547.ABLL_1454	3.463e-15	81.0	COG1669@1|root,COG1669@2|Bacteria,1MZSR@1224|Proteobacteria,42WX7@68525|delta/epsilon subdivisions,2YSEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158347_k127_2027485_1	192952.MM_0636	0.000189	51.0	COG1633@1|root,arCOG01102@2157|Archaea,2Y6AN@28890|Euryarchaeota,2NAYM@224756|Methanomicrobia	224756|Methanomicrobia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158347_k127_2027485_0	1173021.ALWA01000008_gene1562	7.995e-107	361.0	COG0006@1|root,COG0006@2|Bacteria,1G0KH@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158347_k127_2028182_0	5911.EAR91587	2.552e-10	73.0	COG0417@1|root,COG3914@1|root,KOG0968@2759|Eukaryota,KOG4626@2759|Eukaryota,3ZBGB@5878|Ciliophora	5878|Ciliophora	L	DNA polymerase	-	-	2.7.7.7	ko:K02350	ko01100,ko01524,ko03460,map01100,map01524,map03460	M00293	-	-	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,zf-C4pol
SRR25158347_k127_2029056_0	665571.STHERM_c08540	2.577e-46	181.0	COG1022@1|root,COG1022@2|Bacteria,2J59B@203691|Spirochaetes	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_203902_0	102129.Lepto7375DRAFT_2079	1.3e-79	277.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,1H9BF@1150|Oscillatoriales	1117|Cyanobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_2039948_0	1487953.JMKF01000052_gene1663	2.532e-32	131.0	COG0639@1|root,COG0639@2|Bacteria,1G70Z@1117|Cyanobacteria,1HBHY@1150|Oscillatoriales	1117|Cyanobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
SRR25158347_k127_2041260_1	509191.AEDB02000043_gene4764	4.161e-55	203.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WNBT@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158347_k127_2041260_0	871968.DESME_03400	3.332e-64	228.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SRR25158347_k127_2041483_1	340099.Teth39_0935	1.253e-05	53.0	COG3385@1|root,COG3385@2|Bacteria,1V0A5@1239|Firmicutes,24DX5@186801|Clostridia,42HQ1@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158347_k127_2041483_0	373903.Hore_10420	1.829e-07	55.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,24BG9@186801|Clostridia,3WAQ3@53433|Halanaerobiales	186801|Clostridia	K	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
SRR25158347_k127_2041882_1	1122971.BAME01000004_gene618	2.844e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,22X3E@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD
SRR25158347_k127_2041882_0	203119.Cthe_0550	3.014e-60	213.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
SRR25158347_k127_2042176_1	1262449.CP6013_0768	4.189e-12	71.0	COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes,24BB5@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SRR25158347_k127_2042176_0	755178.Cyan10605_2957	1.075e-12	76.0	COG0558@1|root,COG0558@2|Bacteria,1G4ZG@1117|Cyanobacteria	1117|Cyanobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iJN678.pgsA	CDP-OH_P_transf
SRR25158347_k127_2043726_0	583355.Caka_0679	1.443e-60	218.0	COG1305@1|root,COG1305@2|Bacteria,46SQU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158347_k127_2043726_1	595537.Varpa_2215	1.121e-23	116.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,4ABXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158347_k127_2043786_0	313606.M23134_02908	3.021e-17	92.0	COG0123@1|root,COG0123@2|Bacteria,4P0MF@976|Bacteroidetes,47TW8@768503|Cytophagia	976|Bacteroidetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158347_k127_2044270_1	572479.Hprae_1872	6.406e-21	106.0	COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,24CSU@186801|Clostridia,3WBM3@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
SRR25158347_k127_2044270_0	929506.CbC4_1473	6.751e-78	276.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,36ECC@31979|Clostridiaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158347_k127_2044725_0	880073.Calab_0831	4.239e-06	55.0	COG5616@1|root,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,TPR_16
SRR25158347_k127_204990_1	86106.I862_04990	0.0002336	46.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,47EVU@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158347_k127_204990_0	1160707.AJIK01000011_gene2567	3.224e-33	140.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26E4P@186818|Planococcaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU11330	ACP_syn_III,ACP_syn_III_C
SRR25158347_k127_205055_0	1449063.JMLS01000025_gene3955	1.318e-76	271.0	COG5002@1|root,COG5002@2|Bacteria,1UJ5U@1239|Firmicutes,4HG8M@91061|Bacilli,26S07@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
SRR25158347_k127_2052019_0	1408287.AXUR01000095_gene602	1.209e-13	78.0	COG2849@1|root,COG2849@2|Bacteria,37C39@32066|Fusobacteria	32066|Fusobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
SRR25158347_k127_2052474_1	452638.Pnec_1087	1.98e-39	147.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,1JZXX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158347_k127_2052474_0	452638.Pnec_1086	3.292e-292	905.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1K1V8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_2052474_2	56110.Oscil6304_2924	2.376e-11	66.0	COG1943@1|root,COG1943@2|Bacteria,1G7D3@1117|Cyanobacteria,1HBY0@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158347_k127_2052685_0	1229172.JQFA01000002_gene4479	8.76e-159	512.0	COG1012@1|root,COG1012@2|Bacteria,1G3H4@1117|Cyanobacteria,1HEAZ@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_2052685_1	1089439.KB902271_gene2037	1.381e-08	57.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,1RS51@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Gamma-glutamyl-gamma-aminobutyrate hydrolase	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158347_k127_2053232_0	565034.BHWA1_01790	5.876e-07	59.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	2.8.1.1,2.8.1.2	ko:K01011,ko:K06867	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,Rhodanese,SBP_bac_3
SRR25158347_k127_2055221_0	395493.BegalDRAFT_0259	4.951e-92	313.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,462C5@72273|Thiotrichales	72273|Thiotrichales	I	PFAM AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_2055221_1	1217648.F933_01007	4.075e-32	131.0	COG1893@1|root,COG1893@2|Bacteria,1N0M5@1224|Proteobacteria,1RNZY@1236|Gammaproteobacteria,3NM1M@468|Moraxellaceae	1236|Gammaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158347_k127_2056599_0	1168034.FH5T_20815	1.631e-79	278.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,4PN7F@976|Bacteroidetes,2G14N@200643|Bacteroidia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_2057341_1	1123274.KB899426_gene2836	2.307e-22	100.0	COG0629@1|root,COG0629@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158347_k127_2057341_2	926566.Terro_2501	2.971e-09	68.0	28K54@1|root,2Z9TW@2|Bacteria,3Y3Z7@57723|Acidobacteria,2JHS9@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2057341_0	1116472.MGMO_146c00320	2.603e-24	109.0	2F1EJ@1|root,33UF9@2|Bacteria,1NV3G@1224|Proteobacteria,1TI1Z@1236|Gammaproteobacteria,1XGBM@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2057660_1	929712.KI912613_gene4772	1.012e-08	63.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4CP70@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158347_k127_2057660_0	5911.EAR84936	6.447e-75	269.0	COG4642@1|root,KOG0231@2759|Eukaryota,3ZDSC@5878|Ciliophora	5878|Ciliophora	T	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_2058954_1	913865.DOT_1684	0.0002024	54.0	COG4972@1|root,COG4972@2|Bacteria,1V5TW@1239|Firmicutes,24ICR@186801|Clostridia,2633I@186807|Peptococcaceae	186801|Clostridia	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158347_k127_2058954_0	521674.Plim_3639	1.695e-10	72.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
SRR25158347_k127_2058954_2	398767.Glov_1275	0.0003823	50.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
SRR25158347_k127_2060916_0	1203556.HMPREF1478_00708	4.515e-07	63.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2I09Y@201174|Actinobacteria,4D36T@85005|Actinomycetales	201174|Actinobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SRR25158347_k127_2064765_0	498761.HM1_2362	1.262e-30	130.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158347_k127_2064784_1	1249997.JHZW01000002_gene1670	8.57e-81	274.0	COG0702@1|root,COG0702@2|Bacteria,4NZXB@976|Bacteroidetes	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158347_k127_2064784_0	288000.BBta_2539	4.127e-86	302.0	COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,2U05K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158347_k127_2064784_2	43989.cce_0689	1.125e-56	220.0	COG2199@1|root,COG3706@2|Bacteria,1GQ6B@1117|Cyanobacteria,3KJAN@43988|Cyanothece	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158347_k127_2065574_0	5932.XP_004030413.1	3.323e-15	85.0	COG0664@1|root,KOG1113@2759|Eukaryota	2759|Eukaryota	T	cAMP-dependent protein kinase regulator activity	PRKAR1A	GO:0000003,GO:0000166,GO:0000187,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010738,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030435,GO:0030551,GO:0030552,GO:0030554,GO:0030587,GO:0030951,GO:0030952,GO:0031032,GO:0031154,GO:0031156,GO:0031285,GO:0031288,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0043934,GO:0043949,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051703,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0061939,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071902,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0090702,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099120,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRR25158347_k127_2067370_0	1124982.MSI_03290	2.642e-12	79.0	COG4254@1|root,COG4254@2|Bacteria,2J6MW@203691|Spirochaetes	203691|Spirochaetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158347_k127_2069574_0	645991.Sgly_0939	6.272e-37	145.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,260EJ@186807|Peptococcaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_2069574_1	237368.SCABRO_03760	1.619e-27	118.0	COG4587@1|root,COG4587@2|Bacteria,2IYNM@203682|Planctomycetes	203682|Planctomycetes	S	transport system permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158347_k127_2069778_0	1047013.AQSP01000142_gene165	7.586e-94	316.0	COG3591@1|root,COG3591@2|Bacteria,2NQEJ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158347_k127_2070174_0	1132855.KB913035_gene1764	2.642e-38	148.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KMG8@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR25158347_k127_2070174_1	314607.KB13_978	1.998e-06	59.0	COG1538@1|root,COG1538@2|Bacteria,1R6S1@1224|Proteobacteria,2VMHP@28216|Betaproteobacteria,1KR2N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	MU	Outer membrane efflux protein	cusC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158347_k127_2075104_0	880072.Desac_2907	2.924e-134	438.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria,2MRBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
SRR25158347_k127_2075194_0	889378.Spiaf_2874	1.564e-184	587.0	COG0187@1|root,COG0187@2|Bacteria,2J67M@203691|Spirochaetes	203691|Spirochaetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158347_k127_2076318_0	246197.MXAN_3756	1.249e-52	198.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRR25158347_k127_2077991_0	1168034.FH5T_12285	3.69e-67	229.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158347_k127_2077991_2	1048983.EL17_23950	3.98e-05	49.0	2EC8J@1|root,33671@2|Bacteria,4NVSY@976|Bacteroidetes,47SGY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2078835_0	1469557.JSWF01000033_gene1610	8.832e-30	128.0	2F15V@1|root,33U6Z@2|Bacteria,4P2EZ@976|Bacteroidetes,1I8VB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2089529_0	1122927.KB895413_gene1799	5.66e-28	114.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,26RT0@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
SRR25158347_k127_2090079_0	1499967.BAYZ01000033_gene1096	1.892e-77	269.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	rnaZ	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158347_k127_2090079_1	314607.KB13_550	2.422e-76	270.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,1KQBD@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158347_k127_2090079_2	1123306.KB904357_gene614	2.458e-39	149.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158347_k127_209206_0	1045858.Bint_1328	5.324e-49	187.0	COG5009@1|root,COG5009@2|Bacteria,2J5D4@203691|Spirochaetes	203691|Spirochaetes	M	penicillin-binding protein	pbp-3	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_2092110_1	313606.M23134_02981	4.823e-08	64.0	COG0642@1|root,COG2205@2|Bacteria,4NN26@976|Bacteroidetes,47U6C@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
SRR25158347_k127_2092110_0	1304885.AUEY01000049_gene1231	7.85e-12	66.0	COG3541@1|root,COG3541@2|Bacteria,1MYFT@1224|Proteobacteria,42ZKG@68525|delta/epsilon subdivisions,2WUYZ@28221|Deltaproteobacteria,2MNG8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
SRR25158347_k127_2094648_0	933262.AXAM01000033_gene1627	1.585e-72	253.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MJGP@213118|Desulfobacterales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158347_k127_2094648_1	1183377.Py04_0743	1.109e-21	98.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,242WA@183968|Thermococci	183968|Thermococci	F	Aspartate carbamoyltransferase	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158347_k127_2096008_2	935261.JAGL01000012_gene3533	1.277e-13	82.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,43HHR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	MA20_07390	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158347_k127_2096008_1	1173026.Glo7428_3199	4.097e-15	80.0	COG4446@1|root,COG4446@2|Bacteria,1G6W2@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
SRR25158347_k127_2096008_0	662479.C440_09487	1.064e-36	147.0	COG2124@1|root,arCOG02814@2157|Archaea,2XTFX@28890|Euryarchaeota,23S5X@183963|Halobacteria	183963|Halobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158347_k127_2096392_0	203124.Tery_3923	4.15e-34	144.0	COG0457@1|root,COG1672@1|root,COG2319@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7TA@1150|Oscillatoriales	1117|Cyanobacteria	M	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8,WD40
SRR25158347_k127_2096526_1	102232.GLO73106DRAFT_00000480	5.061e-08	55.0	COG2442@1|root,COG2442@2|Bacteria,1GQFK@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
SRR25158347_k127_2096526_2	1125973.JNLC01000014_gene2409	0.0005231	44.0	COG1262@1|root,COG2815@1|root,COG1262@2|Bacteria,COG2815@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
SRR25158347_k127_2096526_0	1288963.ADIS_1340	9.078e-09	57.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,47KU9@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	1.8.3.7	ko:K13444	ko04142,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
SRR25158347_k127_2096526_3	397291.C804_04311	0.0007044	46.0	COG4636@1|root,COG4636@2|Bacteria,1V4N9@1239|Firmicutes,24CZ1@186801|Clostridia,27TTJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158347_k127_2096567_0	1384049.CD29_11760	2.84e-82	291.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3IWDW@400634|Lysinibacillus	91061|Bacilli	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158347_k127_2096567_2	404380.Gbem_1147	0.0002385	49.0	COG1547@1|root,COG1547@2|Bacteria,1NPV3@1224|Proteobacteria,42XAN@68525|delta/epsilon subdivisions,2WSKH@28221|Deltaproteobacteria,43VMV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158347_k127_2096567_1	1128427.KB904821_gene3175	3.82e-05	55.0	COG1538@1|root,COG1538@2|Bacteria,1G0ZP@1117|Cyanobacteria,1H6YB@1150|Oscillatoriales	1117|Cyanobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158347_k127_209736_1	866536.Belba_1343	1.295e-44	164.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_209736_0	1122164.JHWF01000006_gene320	9.118e-128	421.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1JDBU@118969|Legionellales	118969|Legionellales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158347_k127_2097471_1	1341155.FSS13T_04790	4.533e-53	205.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1HY25@117743|Flavobacteriia,2NSIM@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158347_k127_2097471_0	215803.DB30_3447	2.816e-82	288.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_2097471_2	5911.EAS00948	1.401e-07	57.0	COG0664@1|root,KOG1113@2759|Eukaryota	2759|Eukaryota	T	cAMP-dependent protein kinase regulator activity	CNBD2	GO:0000003,GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007276,GO:0007283,GO:0008150,GO:0017076,GO:0019953,GO:0022414,GO:0030551,GO:0030552,GO:0030554,GO:0032501,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0048232,GO:0048609,GO:0051704,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.11.12	ko:K04739,ko:K19477	ko04022,ko04540,ko04611,ko04713,ko04714,ko04730,ko04740,ko04910,ko04923,ko04924,ko04970,map04022,map04540,map04611,map04713,map04714,map04730,map04740,map04910,map04923,map04924,map04970	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	cNMP_binding
SRR25158347_k127_2097582_2	880070.Cycma_4168	1.221e-28	126.0	COG0642@1|root,COG2205@2|Bacteria,4NQ7H@976|Bacteroidetes,47QVS@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA
SRR25158347_k127_2097582_1	2045.KR76_08415	6.684e-29	123.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4DRMX@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158347_k127_2097582_0	1242864.D187_009360	8.335e-36	141.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,42U27@68525|delta/epsilon subdivisions,2WR2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158347_k127_2098043_0	1499967.BAYZ01000061_gene5978	6.368e-25	114.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_2098043_1	1454007.JAUG01000005_gene2869	9.448e-07	51.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158347_k127_2098348_1	272563.CD630_26790	4.33e-22	98.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25R8Y@186804|Peptostreptococcaceae	186801|Clostridia	IQ	3-oxoacyl- acyl-carrier-protein reductase	-	-	1.1.1.100,1.1.1.140,1.1.1.30	ko:K00019,ko:K00059,ko:K00068	ko00051,ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00088,M00572	R01361,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158347_k127_2098348_0	1238450.VIBNISOn1_450068	5.706e-62	219.0	2C388@1|root,30ZIR@2|Bacteria,1RFG7@1224|Proteobacteria,1S4CX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2098348_2	693979.Bache_3060	0.0001836	53.0	COG0457@1|root,COG0457@2|Bacteria,4NFFS@976|Bacteroidetes,2FMYG@200643|Bacteroidia,4AMSH@815|Bacteroidaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
SRR25158347_k127_2098562_0	765911.Thivi_2987	9.234e-100	334.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
SRR25158347_k127_2098562_1	94122.Shewana3_1685	2.114e-07	52.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,2QBAP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158347_k127_209962_0	1121904.ARBP01000002_gene6913	1.214e-94	312.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158347_k127_2105055_0	1449063.JMLS01000017_gene630	4.041e-16	87.0	COG5002@1|root,COG5002@2|Bacteria,1UII2@1239|Firmicutes,4HGW5@91061|Bacilli,26QEY@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_2105055_1	203119.Cthe_2166	8.044e-06	52.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,3WGCG@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_4,PAS_9,SpoIIE
SRR25158347_k127_2105083_0	1304284.L21TH_2260	1.129e-08	67.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia,36H30@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis protein	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
SRR25158347_k127_2105895_1	1232437.KL662001_gene4589	7.134e-22	106.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MJZM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SRR25158347_k127_2105895_0	1121929.KB898665_gene2880	3.562e-41	169.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,47038@74385|Gracilibacillus	91061|Bacilli	NT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
SRR25158347_k127_2107085_0	1265310.CCBD010000043_gene2223	1.131e-65	233.0	COG2267@1|root,COG2267@2|Bacteria,2I8UI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158347_k127_2107085_2	312309.VF_A1056	3.904e-42	157.0	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,1XXJZ@135623|Vibrionales	135623|Vibrionales	S	3D domain protein	DR0488	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2107085_1	443143.GM18_4310	2.577e-51	195.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158347_k127_2108733_0	498761.HM1_2362	1.489e-19	102.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158347_k127_2109977_1	1007103.AFHW01000023_gene260	2.452e-12	69.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,4H9WS@91061|Bacilli,26TNU@186822|Paenibacillaceae	91061|Bacilli	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
SRR25158347_k127_2109977_0	391038.Bphy_7458	4.871e-77	265.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2VK11@28216|Betaproteobacteria,1K5KF@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_2111235_0	246197.MXAN_4938	2.807e-68	248.0	COG4223@1|root,COG4223@2|Bacteria,1NDYH@1224|Proteobacteria,433KY@68525|delta/epsilon subdivisions,2WXPE@28221|Deltaproteobacteria,2YZMD@29|Myxococcales	28221|Deltaproteobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2112212_2	765911.Thivi_0672	2.774e-09	66.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158347_k127_2112212_1	747365.Thena_1060	1.309e-43	170.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,249YG@186801|Clostridia,42JCA@68295|Thermoanaerobacterales	186801|Clostridia	C	COGs COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	-	-	1.1.1.291,1.1.1.60	ko:K00042,ko:K19647	ko00630,ko00760,ko01100,ko01120,map00630,map00760,map01100,map01120	-	R01745,R01747,R07985	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158347_k127_2112212_0	1117314.PCIT_20964	6.984e-55	204.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,2Q096@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08483,ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158347_k127_2113872_0	1307761.L21SP2_1189	3.33e-19	93.0	COG1360@1|root,COG1360@2|Bacteria,2J68Q@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158347_k127_2113872_2	929558.SMGD1_0176	0.0006407	49.0	COG1580@1|root,COG1580@2|Bacteria,1NBUX@1224|Proteobacteria,42RSV@68525|delta/epsilon subdivisions,2YPAW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
SRR25158347_k127_2113872_1	714943.Mucpa_5176	8.043e-18	84.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IQQ6@117747|Sphingobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158347_k127_211518_0	945713.IALB_1905	1.577e-156	513.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158347_k127_2117988_0	744872.Spica_1474	2.599e-82	282.0	COG4786@1|root,COG4786@2|Bacteria,2J5EJ@203691|Spirochaetes	203691|Spirochaetes	N	flagellar basal-body rod protein	flhO	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_2117988_1	1121935.AQXX01000140_gene976	2.44e-55	204.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_2119713_0	1235798.C817_03250	1.361e-18	98.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal
SRR25158347_k127_2123072_0	747365.Thena_1035	5.317e-22	97.0	COG0607@1|root,305HX@2|Bacteria,1VPPG@1239|Firmicutes,24V0S@186801|Clostridia	186801|Clostridia	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR25158347_k127_2123072_1	1121918.ARWE01000001_gene3270	1.157e-11	72.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WKVM@28221|Deltaproteobacteria,43SAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158347_k127_2126110_0	272123.Anacy_0444	2.134e-18	95.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GC5R@1117|Cyanobacteria,1HTVH@1161|Nostocales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_2126110_1	171693.BN988_01909	2.521e-08	64.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,23KC0@182709|Oceanobacillus	91061|Bacilli	KT	LytTr DNA-binding domain	lytT	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
SRR25158347_k127_2126594_0	43989.cce_2609	8.32e-54	192.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,3KGWU@43988|Cyanothece	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158347_k127_2126594_2	862908.BMS_3345	2.964e-38	147.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2MT4N@213481|Bdellovibrionales,2WP93@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158347_k127_2126594_1	1385513.N780_16480	4.915e-50	184.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,2Y9RQ@289201|Pontibacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158347_k127_2127460_1	909663.KI867150_gene491	9.037e-13	73.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_2127460_0	1192034.CAP_2673	1.439e-56	208.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
SRR25158347_k127_213038_0	1121935.AQXX01000120_gene4828	1.212e-73	257.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria,1RQ1B@1236|Gammaproteobacteria,1XM9K@135619|Oceanospirillales	135619|Oceanospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_2130925_0	1173027.Mic7113_1898	5.677e-93	315.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1G0EM@1117|Cyanobacteria,1HAW1@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Response_reg
SRR25158347_k127_2133248_1	1047013.AQSP01000137_gene553	2.74e-27	117.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158347_k127_2133248_0	1122604.JONR01000050_gene3145	5.349e-58	208.0	COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1RN9W@1236|Gammaproteobacteria,1X3N6@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	fabR	-	-	ko:K22105	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158347_k127_2133746_0	1122139.KB907867_gene1191	8.803e-77	262.0	COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RPTX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
SRR25158347_k127_2137601_0	1121920.AUAU01000009_gene1957	5.386e-68	239.0	COG0007@1|root,COG0007@2|Bacteria,3Y4HV@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
SRR25158347_k127_2137601_1	929703.KE386491_gene2461	1.422e-33	137.0	COG1648@1|root,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,47PPT@768503|Cytophagia	976|Bacteroidetes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
SRR25158347_k127_2138010_0	880073.Calab_3776	2.645e-122	403.0	COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158347_k127_2138010_1	1304885.AUEY01000049_gene1231	7.212e-66	230.0	COG3541@1|root,COG3541@2|Bacteria,1MYFT@1224|Proteobacteria,42ZKG@68525|delta/epsilon subdivisions,2WUYZ@28221|Deltaproteobacteria,2MNG8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
SRR25158347_k127_2139139_0	1121918.ARWE01000001_gene1240	9.063e-33	139.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WMIZ@28221|Deltaproteobacteria,43S2P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158347_k127_2140165_1	744872.Spica_0016	5.55e-25	109.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_2140165_0	246194.CHY_1752	5.786e-54	199.0	COG1119@1|root,COG1119@2|Bacteria	2|Bacteria	P	ATPase activity	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.21,3.6.3.34	ko:K02013,ko:K02028,ko:K05776	ko02010,map02010	M00189,M00236,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.3	-	-	ABC_tran
SRR25158347_k127_2140165_2	1304275.C41B8_14055	4.47e-21	97.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158347_k127_2140767_1	321327.CYA_0261	8.621e-76	261.0	COG2988@1|root,COG2988@2|Bacteria,1GC3T@1117|Cyanobacteria,1GZBM@1129|Synechococcus	1117|Cyanobacteria	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
SRR25158347_k127_2140767_0	472759.Nhal_2423	8.456e-133	437.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1WWXK@135613|Chromatiales	135613|Chromatiales	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158347_k127_2140767_2	290399.Arth_0946	0.0003116	44.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158347_k127_2143121_1	946483.Cenrod_1108	9.96e-18	97.0	COG1262@1|root,COG2340@1|root,COG1262@2|Bacteria,COG2340@2|Bacteria,1R21A@1224|Proteobacteria,2WI7Q@28216|Betaproteobacteria,4AG4G@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
SRR25158347_k127_2143121_3	1469245.JFBG01000023_gene1286	7.859e-10	72.0	COG1404@1|root,COG2133@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,1RCVP@1224|Proteobacteria	1224|Proteobacteria	O	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SRR25158347_k127_2143121_0	96561.Dole_1733	2.751e-41	168.0	COG2911@1|root,COG3391@1|root,COG5276@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG5276@2|Bacteria,1QW1C@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
SRR25158347_k127_2143121_2	28072.Nos7524_4424	1.789e-15	89.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Calx-beta,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3
SRR25158347_k127_2146344_0	1321778.HMPREF1982_04276	6.295e-70	247.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,2685P@186813|unclassified Clostridiales	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
SRR25158347_k127_2146344_1	1410632.JHWW01000009_gene2527	5.932e-16	79.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,27PFZ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
SRR25158347_k127_2146344_2	702450.CUW_1434	1.028e-08	58.0	COG4467@1|root,COG4467@2|Bacteria,1VK8R@1239|Firmicutes,3VTNX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
SRR25158347_k127_2156430_0	331869.BAL199_11451	8.013e-52	199.0	COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria,2TR2J@28211|Alphaproteobacteria,4BQ8M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158347_k127_2156430_1	1123242.JH636435_gene2611	1.717e-32	127.0	COG1064@1|root,COG1064@2|Bacteria,2IY4H@203682|Planctomycetes	203682|Planctomycetes	C	alcohol dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_2156460_1	929703.KE386491_gene2448	4.474e-18	85.0	COG2907@1|root,COG2907@2|Bacteria,4NKSM@976|Bacteroidetes	976|Bacteroidetes	S	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158347_k127_2156460_0	929703.KE386491_gene2447	6.034e-52	193.0	COG3496@1|root,COG3496@2|Bacteria,4NM4R@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
SRR25158347_k127_2157225_0	1458275.AZ34_11415	1.035e-100	345.0	COG1196@1|root,COG2114@1|root,COG2770@1|root,COG1196@2|Bacteria,COG2114@2|Bacteria,COG2770@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158347_k127_2157225_1	313606.M23134_08301	6.871e-35	135.0	2DP2P@1|root,3309S@2|Bacteria,4NXNC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2157225_2	468059.AUHA01000006_gene2877	1.307e-23	106.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_2157572_0	1444309.JAQG01000017_gene820	1.507e-146	474.0	COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,26QCS@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the catalase family	katA	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
SRR25158347_k127_2158073_2	1380358.JADJ01000025_gene580	0.0003341	44.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1XKA6@135619|Oceanospirillales	135619|Oceanospirillales	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158347_k127_2158073_3	1282361.ABAC402_16315	0.0009174	44.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158347_k127_2158073_0	459349.CLOAM1624	1.027e-17	96.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,2NPWP@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	pal	-	-	ko:K03286,ko:K03640	-	-	-	-	ko00000,ko02000	1.B.6,2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
SRR25158347_k127_2158073_1	1210884.HG799465_gene11874	8.757e-09	61.0	COG5316@1|root,COG5316@2|Bacteria,2IZ9P@203682|Planctomycetes	203682|Planctomycetes	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SRR25158347_k127_2158879_1	1144275.COCOR_05574	2.273e-08	56.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
SRR25158347_k127_2158879_0	550540.Fbal_0214	5.463e-59	224.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	General Secretion Pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
SRR25158347_k127_2159830_2	682795.AciX8_4291	3.311e-10	63.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria,2JICH@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158347_k127_2159830_1	1347392.CCEZ01000043_gene393	2.1e-21	96.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,24QIM@186801|Clostridia,36KQP@31979|Clostridiaceae	186801|Clostridia	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
SRR25158347_k127_2159830_0	635013.TherJR_2830	7.266e-77	271.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,2613M@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158347_k127_2160907_0	56110.Oscil6304_4527	1.029e-130	427.0	COG0745@1|root,COG2114@1|root,COG4252@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG4252@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_2161591_0	1268072.PSAB_07815	4.827e-28	123.0	COG0778@1|root,COG0778@2|Bacteria,1TRKR@1239|Firmicutes,4HNKJ@91061|Bacilli,26SRW@186822|Paenibacillaceae	91061|Bacilli	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158347_k127_2163084_0	435908.IDSA_06360	2.554e-22	108.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,2QEZZ@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	cytochrome	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158347_k127_2163154_2	1437448.AZRT01000188_gene4131	0.0001622	48.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TQV2@28211|Alphaproteobacteria,1J3IK@118882|Brucellaceae	28211|Alphaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158347_k127_2163154_0	1380387.JADM01000015_gene1625	4.544e-17	89.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,1XRJW@135619|Oceanospirillales	135619|Oceanospirillales	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158347_k127_2163154_1	2074.JNYD01000012_gene437	1.053e-06	58.0	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158347_k127_2163879_0	330214.NIDE1868	1.667e-152	491.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae	40117|Nitrospirae	H	Pterin binding enzyme	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
SRR25158347_k127_2163879_1	688269.Theth_0595	4.912e-14	81.0	COG2208@1|root,COG2208@2|Bacteria,2GDGV@200918|Thermotogae	200918|Thermotogae	T	Stage II sporulation	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
SRR25158347_k127_2165013_1	1304880.JAGB01000001_gene951	7.638e-27	115.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2165013_2	749222.Nitsa_2035	1.706e-16	89.0	COG3836@1|root,COG3836@2|Bacteria,1R78B@1224|Proteobacteria,42PJ0@68525|delta/epsilon subdivisions,2YM8R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158347_k127_2165013_0	1121930.AQXG01000002_gene2065	4.221e-29	124.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	petH	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02287,ko:K02641,ko:K15511	ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	iJN678.petH	CpcD,FAD_binding_6,Fer4,NAD_binding_1
SRR25158347_k127_2165422_0	309799.DICTH_1256	5.241e-16	79.0	COG0527@1|root,COG0527@2|Bacteria	2|Bacteria	E	aspartate kinase activity	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158347_k127_2165423_0	1173029.JH980292_gene1971	3.933e-48	175.0	COG2114@1|root,COG2203@1|root,COG3437@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,1G3VR@1117|Cyanobacteria,1H8A5@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PAS_4,Response_reg
SRR25158347_k127_2167885_1	589924.Ferp_1907	6.056e-17	90.0	COG1024@1|root,arCOG00239@2157|Archaea,2Y2NP@28890|Euryarchaeota,246M0@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_2167885_0	331678.Cphamn1_1066	9.788e-53	198.0	COG0841@1|root,COG0841@2|Bacteria,1FEYE@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_2169776_0	1266925.JHVX01000015_gene220	2.957e-89	308.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,2W2SK@28216|Betaproteobacteria,372NV@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
SRR25158347_k127_2171549_0	319003.Bra1253DRAFT_00345	1.174e-18	92.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQX3@28211|Alphaproteobacteria,3JR5W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Pkinase
SRR25158347_k127_2171698_2	1037409.BJ6T_37240	2.015e-06	55.0	COG3239@1|root,COG3239@2|Bacteria,1NIZS@1224|Proteobacteria,2UNUT@28211|Alphaproteobacteria,3K2D7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158347_k127_2171698_0	1116472.MGMO_94c00190	1.833e-150	481.0	COG0451@1|root,COG0451@2|Bacteria,1R4Q0@1224|Proteobacteria,1SZHT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158347_k127_2171698_1	234267.Acid_0551	1.885e-15	76.0	COG0176@1|root,COG0176@2|Bacteria,3Y4PT@57723|Acidobacteria	57723|Acidobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158347_k127_2171763_0	929556.Solca_2394	2.758e-98	344.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg,TPR_12,TPR_8
SRR25158347_k127_2171796_0	1347086.CCBA010000027_gene3547	8.861e-22	101.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZAPC@1386|Bacillus	91061|Bacilli	U	Belongs to the peptidase S26 family	spsB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158347_k127_2172203_0	985867.AEWF01000007_gene448	8.741e-06	49.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,47EU5@766|Rickettsiales	766|Rickettsiales	M	Lipoprotein releasing system transmembrane protein	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158347_k127_2172515_0	999419.HMPREF1077_00772	1.898e-05	52.0	COG1366@1|root,COG1366@2|Bacteria,4NZQX@976|Bacteroidetes	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158347_k127_2175575_0	331678.Cphamn1_0264	6.959e-26	117.0	COG3178@1|root,COG3178@2|Bacteria,1FEBN@1090|Chlorobi	1090|Chlorobi	S	PFAM aminoglycoside phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158347_k127_2175575_1	1002672.SAR11G3_00303	5.451e-20	99.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,4BQCQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	JM	Nucleotidyl transferase	MA20_24100	-	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
SRR25158347_k127_2175960_0	1502850.FG91_02127	5.344e-159	509.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2TV1G@28211|Alphaproteobacteria,2K2KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158347_k127_2175960_1	1408473.JHXO01000004_gene6	7.646e-63	222.0	COG5002@1|root,COG5002@2|Bacteria,4PMM9@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158347_k127_2176326_1	1041147.AUFB01000001_gene4560	2.179e-19	93.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,2U1K0@28211|Alphaproteobacteria,4BAR1@82115|Rhizobiaceae	28211|Alphaproteobacteria	KT	Sigma factor PP2C-like phosphatases	sigB	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
SRR25158347_k127_2176326_0	237368.SCABRO_00164	8.184e-32	140.0	COG2114@1|root,COG2114@2|Bacteria,2J38V@203682|Planctomycetes	203682|Planctomycetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158347_k127_217724_1	1031288.AXAA01000009_gene745	5.766e-13	71.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,248B2@186801|Clostridia,36HRR@31979|Clostridiaceae	186801|Clostridia	S	PFAM transposase YhgA family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
SRR25158347_k127_217724_0	314345.SPV1_08126	1.477e-15	83.0	COG0421@1|root,COG0457@1|root,COG0421@2|Bacteria,COG0457@2|Bacteria,1QYV9@1224|Proteobacteria	1224|Proteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158347_k127_2180985_1	771875.Ferpe_0045	1.505e-27	113.0	COG0178@1|root,COG0178@2|Bacteria,2GCER@200918|Thermotogae	200918|Thermotogae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158347_k127_2180985_0	1499967.BAYZ01000061_gene5969	4.437e-68	239.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_2183745_1	573061.Clocel_0960	1.592e-77	271.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36KBS@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg,dCache_3,sCache_3_3
SRR25158347_k127_2183745_0	1089548.KI783301_gene2821	1.259e-161	518.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,3WFAX@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
SRR25158347_k127_2186276_0	771875.Ferpe_1231	6.041e-119	392.0	COG1501@1|root,COG1501@2|Bacteria,2GDY1@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.199	ko:K15922	-	-	R00802,R11543	RC00028,RC00059,RC00077,RC00451	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
SRR25158347_k127_2186705_0	1121904.ARBP01000033_gene3183	3.856e-41	162.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_2186833_2	497965.Cyan7822_1790	1.992e-05	49.0	COG4942@1|root,COG4942@2|Bacteria	2|Bacteria	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
SRR25158347_k127_2186833_1	1499967.BAYZ01000078_gene997	3.166e-33	135.0	2CB46@1|root,31GHU@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
SRR25158347_k127_2186833_0	1122139.KB907867_gene1191	1.671e-147	493.0	COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RPTX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
SRR25158347_k127_2187040_1	457570.Nther_0464	2.822e-78	269.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158347_k127_2187040_2	1356852.N008_13205	2.59e-12	71.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,47RQP@768503|Cytophagia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158347_k127_2187040_0	864702.OsccyDRAFT_2545	2.999e-149	485.0	COG0004@1|root,COG0642@1|root,COG2199@1|root,COG0004@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HHZA@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_2187116_1	714943.Mucpa_4875	1.093e-31	128.0	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,1J0UU@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
SRR25158347_k127_2187116_0	1196323.ALKF01000204_gene4358	1.382e-72	252.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,26RK6@186822|Paenibacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158347_k127_2187811_0	1107311.Q767_07895	1.096e-18	92.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia,2NSJR@237|Flavobacterium	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158347_k127_2187811_1	1539298.JO41_09215	9.471e-06	55.0	2EY48@1|root,33UVP@2|Bacteria,2J5KT@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar filament outer layer protein FlaA	-	-	-	-	-	-	-	-	-	-	-	-	FlaA
SRR25158347_k127_2188107_0	1131269.AQVV01000030_gene275	5.846e-68	243.0	29MQ2@1|root,308MT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2188242_0	1121890.AUDO01000012_gene2390	1.487e-107	373.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia,2NSZD@237|Flavobacterium	976|Bacteroidetes	S	penicillin amidase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158347_k127_2188242_1	761193.Runsl_0269	2.462e-12	69.0	COG1413@1|root,COG2905@1|root,COG1413@2|Bacteria,COG2905@2|Bacteria,4PKPI@976|Bacteroidetes,47YF3@768503|Cytophagia	976|Bacteroidetes	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
SRR25158347_k127_2188826_0	765420.OSCT_0756	5.563e-08	66.0	COG3850@1|root,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,HisKA_7TM,MFS_1
SRR25158347_k127_2190486_2	316275.VSAL_II1032	5.209e-08	63.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XSWS@135623|Vibrionales	135623|Vibrionales	E	COG0560 Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158347_k127_2190486_0	1499967.BAYZ01000033_gene1096	1.778e-80	279.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	rnaZ	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158347_k127_2190486_1	247490.KSU1_C1317	2.435e-12	74.0	2C7TA@1|root,2Z9TR@2|Bacteria,2IXIJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2192486_0	1316936.K678_04784	5.696e-49	183.0	COG1396@1|root,COG1396@2|Bacteria,1RE8Z@1224|Proteobacteria,2TXJM@28211|Alphaproteobacteria,2JTNG@204441|Rhodospirillales	204441|Rhodospirillales	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158347_k127_2193081_1	468059.AUHA01000002_gene833	1.366e-71	254.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,1IP32@117747|Sphingobacteriia	976|Bacteroidetes	P	sodium proton antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158347_k127_2193081_0	935837.JAEK01000010_gene58	7.871e-138	460.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus	91061|Bacilli	I	Biotin carboxylase	yngH	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158347_k127_2195276_0	543728.Vapar_2956	3.797e-21	95.0	COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,2VNTX@28216|Betaproteobacteria,4ACN4@80864|Comamonadaceae	28216|Betaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2198809_0	756272.Plabr_4280	6.47e-10	72.0	COG4285@1|root,COG4285@2|Bacteria,2J0H1@203682|Planctomycetes	203682|Planctomycetes	V	biotin apo-protein ligase-related	-	-	-	-	-	-	-	-	-	-	-	-	BPL_N
SRR25158347_k127_2198809_1	392500.Swoo_4747	3.752e-06	49.0	COG0322@1|root,COG0322@2|Bacteria,1R5TC@1224|Proteobacteria,1S0PX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4357)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4357
SRR25158347_k127_220049_0	1001585.MDS_1956	2.966e-43	162.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1YHQ9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Chorismate mutase type II	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158347_k127_220049_1	1114965.Spaf_0863	1.18e-38	156.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli	91061|Bacilli	E	prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22610	ACT,PDH
SRR25158347_k127_22011_1	585394.RHOM_12070	5.047e-05	47.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_22011_2	1379698.RBG1_1C00001G1156	0.0001411	45.0	COG0618@1|root,COG0618@2|Bacteria,2NPK0@2323|unclassified Bacteria	2|Bacteria	S	DHH family	nrnA	GO:0008150,GO:0040007	2.7.7.72,3.1.13.3,3.1.3.7	ko:K00974,ko:K06881	ko00920,ko01100,ko01120,ko03013,map00920,map01100,map01120,map03013	-	R00188,R00508,R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03400	-	-	-	DHH,DHHA1
SRR25158347_k127_22011_0	246199.CUS_7299	4.506e-27	121.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158347_k127_2202637_0	936589.HMPREF1521_0109	3.633e-165	532.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4H24Z@909932|Negativicutes	909932|Negativicutes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158347_k127_2206504_0	641524.ADICYQ_3175	1.219e-206	647.0	COG2303@1|root,COG2303@2|Bacteria,4NI42@976|Bacteroidetes,47MET@768503|Cytophagia	976|Bacteroidetes	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158347_k127_2206504_2	10228.TriadP24634	5.632e-19	101.0	COG2124@1|root,KOG0158@2759|Eukaryota,38BTY@33154|Opisthokonta,3BF8S@33208|Metazoa	33208|Metazoa	Q	heme binding	TBXAS1	GO:0001101,GO:0001516,GO:0001676,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004796,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006873,GO:0008015,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009636,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016860,GO:0019229,GO:0019369,GO:0019371,GO:0019725,GO:0019752,GO:0030002,GO:0030320,GO:0030644,GO:0031984,GO:0032501,GO:0032787,GO:0033559,GO:0033993,GO:0035150,GO:0035296,GO:0036134,GO:0042175,GO:0042221,GO:0042493,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044057,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045471,GO:0045907,GO:0046394,GO:0046456,GO:0046457,GO:0046677,GO:0048518,GO:0048878,GO:0050789,GO:0050801,GO:0050880,GO:0050896,GO:0051239,GO:0051240,GO:0055064,GO:0055081,GO:0055082,GO:0055083,GO:0055114,GO:0065007,GO:0065008,GO:0070542,GO:0071704,GO:0072330,GO:0090066,GO:0097305,GO:0097746,GO:0098771,GO:0098827,GO:1901568,GO:1901570,GO:1901576,GO:1901700,GO:1903522,GO:1903524	1.14.14.1,5.3.99.5	ko:K01832,ko:K07424	ko00140,ko00590,ko00591,ko00830,ko01100,ko04611,ko05204,map00140,map00590,map00591,map00830,map01100,map04611,map05204	-	R02268,R02356,R03408,R07055,R07056,R08390,R08391,R08392	RC00674,RC00704,RC00723,RC00724,RC01624,RC01711	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158347_k127_2206504_1	317936.Nos7107_2708	4.897e-36	138.0	2DQG9@1|root,336P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2207154_1	317936.Nos7107_2837	1.181e-25	111.0	2C9PJ@1|root,30PCX@2|Bacteria,1G5ZE@1117|Cyanobacteria,1HNHC@1161|Nostocales	1117|Cyanobacteria	S	PFAM XisI protein	-	-	-	-	-	-	-	-	-	-	-	-	XisI
SRR25158347_k127_2207154_2	421531.IX38_21930	1.448e-25	109.0	2E5G8@1|root,3307X@2|Bacteria,4NU4B@976|Bacteroidetes,1I45E@117743|Flavobacteriia	976|Bacteroidetes	S	Immunity protein 53	-	-	-	-	-	-	-	-	-	-	-	-	Imm53
SRR25158347_k127_2207154_3	1173026.Glo7428_4212	7.698e-25	107.0	2C9PJ@1|root,30CJG@2|Bacteria	2|Bacteria	S	XisI protein	-	-	-	-	-	-	-	-	-	-	-	-	XisI
SRR25158347_k127_2207154_0	1469607.KK073768_gene2632	1.878e-36	141.0	296N4@1|root,30EW3@2|Bacteria,1G6D0@1117|Cyanobacteria,1HN5N@1161|Nostocales	1117|Cyanobacteria	S	PFAM XisH protein	-	-	-	-	-	-	-	-	-	-	-	-	XisH
SRR25158347_k127_2209209_1	1048983.EL17_15115	1.084e-24	112.0	28T0B@1|root,2ZF9N@2|Bacteria,4P6RT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2209209_0	1048983.EL17_15110	5.743e-38	144.0	COG4938@1|root,COG4938@2|Bacteria,4NMVA@976|Bacteroidetes,47RR9@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3696)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,DUF3696
SRR25158347_k127_2209311_0	215803.DB30_7756	9.61e-47	180.0	COG0330@1|root,COG0330@2|Bacteria,1Q1RS@1224|Proteobacteria,437F1@68525|delta/epsilon subdivisions,2X2MG@28221|Deltaproteobacteria,2YTT6@29|Myxococcales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_2210187_0	203124.Tery_2760	8.215e-16	89.0	COG4249@1|root,COG4249@2|Bacteria,1GPWG@1117|Cyanobacteria,1HBAE@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158347_k127_2212627_0	439235.Dalk_1258	1.191e-59	220.0	COG2114@1|root,COG2703@1|root,COG2114@2|Bacteria,COG2703@2|Bacteria,1MW5Z@1224|Proteobacteria,42RM8@68525|delta/epsilon subdivisions,2WNZ4@28221|Deltaproteobacteria,2MKKN@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Guanylate_cyc,Hemerythrin
SRR25158347_k127_2212627_1	639282.DEFDS_1929	9.306e-54	199.0	COG0183@1|root,COG0183@2|Bacteria,2GF0X@200930|Deferribacteres	200930|Deferribacteres	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_2214574_0	1280689.AUJC01000004_gene380	2.768e-26	126.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,36EG4@31979|Clostridiaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158347_k127_2217837_2	218284.CCDN010000001_gene721	2.545e-05	50.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus	91061|Bacilli	L	COG1555 DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158347_k127_2217837_1	619693.HMPREF6745_2395	2.549e-12	72.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	ATP-synt_DE,ATP-synt_DE_N
SRR25158347_k127_2217837_0	1073999.BN137_3189	2.491e-43	158.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658	ATP-synt_ab,ATP-synt_ab_N
SRR25158347_k127_2222248_1	1173028.ANKO01000017_gene82	1.557e-38	167.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_2222248_0	293826.Amet_4420	8.949e-50	203.0	COG2199@1|root,COG3706@2|Bacteria,1TR5R@1239|Firmicutes,24E9M@186801|Clostridia,36FFC@31979|Clostridiaceae	186801|Clostridia	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
SRR25158347_k127_2222248_2	376686.Fjoh_5035	1.668e-05	54.0	COG1629@1|root,COG2304@1|root,COG1629@2|Bacteria,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1HY6K@117743|Flavobacteriia,2NSJD@237|Flavobacterium	976|Bacteroidetes	P	Von Willebrand factor	yfbK	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,Plug,TSP_3,VWA,vWF_A
SRR25158347_k127_2223706_0	313606.M23134_03202	6.989e-245	772.0	COG0330@1|root,COG0330@2|Bacteria,4NKQ8@976|Bacteroidetes,47TJM@768503|Cytophagia	976|Bacteroidetes	O	Shoulder domain	-	-	-	ko:K17266	-	-	-	-	ko00000,ko04147	-	-	-	MVP_shoulder
SRR25158347_k127_2224769_1	391625.PPSIR1_12793	1.727e-18	94.0	COG1262@1|root,COG1262@2|Bacteria,1QA4V@1224|Proteobacteria,43DXT@68525|delta/epsilon subdivisions,2WZ5G@28221|Deltaproteobacteria,2Z1DE@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2224769_0	1123256.KB907928_gene1969	1.509e-19	92.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1X7ZG@135614|Xanthomonadales	135614|Xanthomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158347_k127_2225538_1	877418.ATWV01000004_gene1827	2.359e-21	102.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_2225538_0	933262.AXAM01000023_gene655	4.59e-53	191.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,42S4I@68525|delta/epsilon subdivisions,2WNXV@28221|Deltaproteobacteria,2MNF8@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG3	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_2228401_3	1487921.DP68_04470	1.464e-14	77.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,36E5Q@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158347_k127_2228401_2	1123499.KB908024_gene1424	2.518e-16	84.0	COG0824@1|root,COG0824@2|Bacteria,1RF7Q@1224|Proteobacteria,2VR5T@28216|Betaproteobacteria,2KRGT@206351|Neisseriales	206351|Neisseriales	S	thioesterase K01075	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
SRR25158347_k127_2228401_0	1541065.JRFE01000008_gene5001	8.184e-73	253.0	COG1028@1|root,COG1028@2|Bacteria,1G2ZD@1117|Cyanobacteria,3VM8E@52604|Pleurocapsales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_2228401_1	56107.Cylst_4769	3.631e-53	194.0	COG1028@1|root,COG1028@2|Bacteria,1G2ZD@1117|Cyanobacteria,1HK9F@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158347_k127_2229085_0	330214.NIDE1118	3.683e-22	104.0	COG4783@1|root,COG4783@2|Bacteria,3J193@40117|Nitrospirae	40117|Nitrospirae	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158347_k127_2229142_0	1347393.HG726020_gene1599	6.698e-43	161.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,2FNBV@200643|Bacteroidia,4ANC3@815|Bacteroidaceae	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C,Radical_SAM
SRR25158347_k127_2229142_1	909943.HIMB100_00009400	3.283e-09	65.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,4BQG4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15,4.4.1.25	ko:K05396,ko:K17950	ko00270,map00270	-	R01874,R07634	RC00382,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158347_k127_222950_1	522772.Dacet_1496	2.122e-17	86.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-2	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158347_k127_222950_0	926569.ANT_27000	1.088e-17	88.0	COG0071@1|root,COG0071@2|Bacteria,2G9EM@200795|Chloroflexi	200795|Chloroflexi	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158347_k127_2231179_1	1278307.KB907029_gene459	2.325e-67	236.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158347_k127_2231179_0	1408473.JHXO01000008_gene2741	3.376e-69	240.0	COG0451@1|root,COG0451@2|Bacteria,4NJ2M@976|Bacteroidetes	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158347_k127_2234781_0	1398491.P613_01060	3.34e-05	56.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158347_k127_2236324_0	373994.Riv7116_2325	3.716e-76	262.0	COG0524@1|root,COG0524@2|Bacteria,1G3P8@1117|Cyanobacteria,1HMEC@1161|Nostocales	1117|Cyanobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158347_k127_2236324_1	56110.Oscil6304_1357	1.024e-74	260.0	COG0697@1|root,COG0697@2|Bacteria,1G0UQ@1117|Cyanobacteria,1H7NC@1150|Oscillatoriales	1117|Cyanobacteria	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_2236401_0	583355.Caka_2319	8.741e-08	64.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,3K735@414999|Opitutae	414999|Opitutae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
SRR25158347_k127_2236509_1	1433126.BN938_2139	1.619e-09	63.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,2FNY9@200643|Bacteroidia,22U1A@171550|Rikenellaceae	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
SRR25158347_k127_2236509_0	756067.MicvaDRAFT_1141	5.649e-15	87.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
SRR25158347_k127_2236688_1	331869.BAL199_04734	0.0001261	51.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TSVG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158347_k127_2236688_0	1232437.KL662013_gene1351	1.925e-41	164.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WMGU@28221|Deltaproteobacteria,2MI8K@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158347_k127_2237822_0	869213.JCM21142_93839	1.587e-05	57.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158347_k127_2238573_0	1173022.Cri9333_2959	5.279e-71	255.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_9
SRR25158347_k127_2238573_1	91464.S7335_1924	1.205e-27	115.0	COG0745@1|root,COG2207@1|root,COG0745@2|Bacteria,COG2207@2|Bacteria,1GD4T@1117|Cyanobacteria,1H0B2@1129|Synechococcus	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
SRR25158347_k127_2239742_0	56110.Oscil6304_5443	1.571e-95	321.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Hpt,Pkinase,Response_reg
SRR25158347_k127_2239742_1	929558.SMGD1_1664	0.0005817	44.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
SRR25158347_k127_2242748_0	635013.TherJR_2186	8.634e-103	343.0	COG3621@1|root,COG3621@2|Bacteria,1UYFU@1239|Firmicutes,25DW4@186801|Clostridia	186801|Clostridia	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158347_k127_2244359_0	906968.Trebr_0116	1.717e-117	394.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,2J5GP@203691|Spirochaetes	203691|Spirochaetes	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158347_k127_2246176_2	639030.JHVA01000001_gene1042	1.014e-15	81.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158347_k127_2246176_0	1235803.C825_01513	1.131e-79	274.0	2DBB3@1|root,2Z85F@2|Bacteria,4NKCY@976|Bacteroidetes,2FPU7@200643|Bacteroidia,22ZIC@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
SRR25158347_k127_2246176_1	395493.BegalDRAFT_2361	1.124e-39	161.0	COG1672@1|root,COG3755@1|root,COG1672@2|Bacteria,COG3755@2|Bacteria	2|Bacteria	S	Lysozyme inhibitor LprI	-	-	-	ko:K06894,ko:K06921	-	-	-	-	ko00000	-	-	-	LprI
SRR25158347_k127_224628_0	459349.CLOAM1841	4.382e-96	323.0	COG0726@1|root,COG0726@2|Bacteria,2NPFG@2323|unclassified Bacteria	2|Bacteria	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
SRR25158347_k127_2247823_0	927658.AJUM01000010_gene1352	3.992e-74	275.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2FRUD@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_2248419_0	641526.ADIWIN_1863	4.754e-41	159.0	COG0683@1|root,COG0683@2|Bacteria,4NIVQ@976|Bacteroidetes,1HZ6K@117743|Flavobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2248419_2	1313301.AUGC01000004_gene2261	2.923e-19	90.0	COG0683@1|root,COG0683@2|Bacteria,4NIVQ@976|Bacteroidetes	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2248419_1	483216.BACEGG_01249	5.136e-32	138.0	COG0399@1|root,COG0399@2|Bacteria,4NGI4@976|Bacteroidetes,2FP2I@200643|Bacteroidia,4AM3H@815|Bacteroidaceae	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158347_k127_2250280_0	1289135.A966_11851	5.006e-27	120.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2J6I1@203691|Spirochaetes	203691|Spirochaetes	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
SRR25158347_k127_2250280_2	483219.LILAB_30490	9.404e-13	76.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42VN1@68525|delta/epsilon subdivisions,2WRVD@28221|Deltaproteobacteria,2YVPX@29|Myxococcales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158347_k127_2250280_1	1173027.Mic7113_4950	1.2e-20	96.0	COG3239@1|root,COG3239@2|Bacteria,1FZVK@1117|Cyanobacteria,1H7Z4@1150|Oscillatoriales	1117|Cyanobacteria	I	Fatty acid desaturase	desB	-	1.14.19.23,1.14.19.25,1.14.19.35,1.14.19.36,1.14.19.45	ko:K10255,ko:K10257	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	DUF3474,FA_desaturase
SRR25158347_k127_2265069_0	1313421.JHBV01000040_gene2586	1.008e-256	809.0	COG0277@1|root,COG3152@1|root,COG4798@1|root,COG0277@2|Bacteria,COG3152@2|Bacteria,COG4798@2|Bacteria,4NHFC@976|Bacteroidetes,1IUJ0@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
SRR25158347_k127_2265069_1	189753.AXAS01000023_gene799	2.613e-38	151.0	COG0596@1|root,COG0596@2|Bacteria,1NU1Q@1224|Proteobacteria,2U3QC@28211|Alphaproteobacteria,3JW5F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Biotin_lipoyl
SRR25158347_k127_22658_0	693977.Deipr_1106	8.564e-114	378.0	COG0578@1|root,COG0578@2|Bacteria,1WITW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158347_k127_2265888_3	575590.HMPREF0156_00441	1.729e-11	66.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158347_k127_2265888_2	218495.SUB0203	6.549e-13	78.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli	91061|Bacilli	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2265888_0	1123325.JHUV01000011_gene1553	1.472e-46	181.0	COG2265@1|root,COG2265@2|Bacteria,2G3V7@200783|Aquificae	200783|Aquificae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
SRR25158347_k127_2265888_1	335541.Swol_0247	2.592e-17	94.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42JW5@68298|Syntrophomonadaceae	186801|Clostridia	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_2267200_0	391625.PPSIR1_12793	3.241e-33	142.0	COG1262@1|root,COG1262@2|Bacteria,1QA4V@1224|Proteobacteria,43DXT@68525|delta/epsilon subdivisions,2WZ5G@28221|Deltaproteobacteria,2Z1DE@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2267200_1	1385510.N781_13560	6.156e-25	107.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,2Y994@289201|Pontibacillus	91061|Bacilli	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
SRR25158347_k127_2267200_2	526224.Bmur_0805	1.755e-19	93.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
SRR25158347_k127_226903_1	1480694.DC28_01315	1.004e-15	76.0	COG4786@1|root,COG4786@2|Bacteria,2J57D@203691|Spirochaetes	203691|Spirochaetes	N	flagellar basal-body rod protein FlgG	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_226903_0	745718.JADT01000011_gene752	1.221e-45	176.0	COG0739@1|root,COG0739@2|Bacteria,4NMHB@976|Bacteroidetes,1I1UE@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_226903_2	1047171.Mycgr3P93378	2.212e-05	55.0	COG0666@1|root,KOG0504@2759|Eukaryota,39Q5R@33154|Opisthokonta,3Q6BV@4751|Fungi,3RPBK@4890|Ascomycota	4751|Fungi	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2270112_0	1408473.JHXO01000015_gene1905	1.573e-86	304.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2FM06@200643|Bacteroidia	976|Bacteroidetes	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_2270112_1	1392488.JHZY01000004_gene3331	1.982e-42	158.0	2C85M@1|root,31GSX@2|Bacteria,4NQEM@976|Bacteroidetes,1I48Z@117743|Flavobacteriia,2XJH5@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158347_k127_227156_0	443254.Marpi_1633	2.541e-30	133.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GCU2@200918|Thermotogae	200918|Thermotogae	KT	Stage II sporulation	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
SRR25158347_k127_227156_1	1254432.SCE1572_37175	4.356e-07	61.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
SRR25158347_k127_2272661_0	290512.Paes_1402	2.745e-41	159.0	COG0841@1|root,COG0841@2|Bacteria,1FEYE@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_2274587_0	926569.ANT_22130	1.581e-44	171.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
SRR25158347_k127_2275152_0	1123274.KB899413_gene854	4.211e-52	196.0	COG1536@1|root,COG1536@2|Bacteria,2J5CI@203691|Spirochaetes	203691|Spirochaetes	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
SRR25158347_k127_2275718_0	323259.Mhun_1766	9.254e-60	211.0	arCOG01426@1|root,arCOG01426@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2280681_1	1408433.JHXV01000005_gene2345	2.88e-33	140.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IMRQ@117743|Flavobacteriia,2PBRV@246874|Cryomorphaceae	976|Bacteroidetes	I	GHMP kinases C terminal	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158347_k127_2280681_2	487316.BBNM01000009_gene2648	0.0002559	46.0	2AZTC@1|root,31S2K@2|Bacteria,1QPJP@1224|Proteobacteria,1TNA5@1236|Gammaproteobacteria,3NQ8M@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2280681_0	1123371.ATXH01000021_gene1128	7.47e-60	215.0	COG1207@1|root,COG1207@2|Bacteria,2GI7A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158347_k127_2287862_1	1313265.JNIE01000007_gene3	1.603e-07	58.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158347_k127_2287862_2	1121441.AUCX01000015_gene3471	3.136e-07	57.0	COG1366@1|root,COG1366@2|Bacteria,1QSND@1224|Proteobacteria,437IV@68525|delta/epsilon subdivisions,2WYKP@28221|Deltaproteobacteria,2M99M@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158347_k127_2287862_0	1454007.JAUG01000062_gene600	1.911e-44	165.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,1IPD9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_2288045_0	745014.OMB55_00010790	8.817e-47	173.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158347_k127_2288074_0	290397.Adeh_0917	7.454e-08	61.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2Z380@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2
SRR25158347_k127_2291737_0	406552.NJ7G_0043	5.159e-23	110.0	COG1331@1|root,arCOG10872@1|root,arCOG02007@2157|Archaea,arCOG10872@2157|Archaea,2XVMH@28890|Euryarchaeota,240YA@183963|Halobacteria	183963|Halobacteria	O	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
SRR25158347_k127_2293900_0	880526.KE386488_gene1305	6.329e-31	124.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,2FRF9@200643|Bacteroidia,22V2K@171550|Rikenellaceae	976|Bacteroidetes	C	Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158347_k127_2293900_1	682795.AciX8_4244	3.913e-08	65.0	COG1538@1|root,COG1538@2|Bacteria,3Y2KH@57723|Acidobacteria,2JIJE@204432|Acidobacteriia	204432|Acidobacteriia	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158347_k127_2294402_2	1347086.CCBA010000006_gene4636	2.23e-06	53.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4HKVS@91061|Bacilli,1ZI12@1386|Bacillus	91061|Bacilli	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
SRR25158347_k127_2294402_0	526224.Bmur_0184	5.186e-38	152.0	COG1684@1|root,COG1684@2|Bacteria,2J6DD@203691|Spirochaetes	203691|Spirochaetes	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
SRR25158347_k127_2294402_1	744872.Spica_1526	1.388e-13	76.0	COG1377@1|root,COG1377@2|Bacteria,2J5EU@203691|Spirochaetes	203691|Spirochaetes	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
SRR25158347_k127_2296724_0	382464.ABSI01000012_gene2041	2.535e-89	305.0	COG3004@1|root,COG3004@2|Bacteria,46XIZ@74201|Verrucomicrobia,2IW1K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1
SRR25158347_k127_2296724_1	1304284.L21TH_0932	1.014e-29	129.0	COG0747@1|root,COG0840@1|root,COG0747@2|Bacteria,COG0840@2|Bacteria,1UI2C@1239|Firmicutes,25EAX@186801|Clostridia,36G0A@31979|Clostridiaceae	186801|Clostridia	ENT	extracellular solute-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,SBP_bac_5
SRR25158347_k127_2299160_0	744872.Spica_1382	3.831e-64	243.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2J6FV@203691|Spirochaetes	203691|Spirochaetes	T	Adenylate guanylate cyclase catalytic domain protein	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158347_k127_2300659_3	563008.HMPREF0665_02240	2.989e-18	89.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FMX8@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158347_k127_2300659_2	357808.RoseRS_2760	2.3e-25	113.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158347_k127_2300659_0	1304284.L21TH_1617	7.359e-73	253.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158347_k127_2300659_1	644282.Deba_1226	3.242e-27	125.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
SRR25158347_k127_230130_0	1121930.AQXG01000001_gene1206	1.136e-60	218.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1IPKH@117747|Sphingobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
SRR25158347_k127_2303690_0	1121918.ARWE01000001_gene2375	7.255e-87	297.0	COG0531@1|root,COG1762@1|root,COG0531@2|Bacteria,COG1762@2|Bacteria,1MXNJ@1224|Proteobacteria,43A4W@68525|delta/epsilon subdivisions,2X2I0@28221|Deltaproteobacteria,43VI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158347_k127_2303690_1	880073.Calab_0097	9.402e-75	258.0	COG4099@1|root,COG4099@2|Bacteria,2NQ8A@2323|unclassified Bacteria	2|Bacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Esterase_phd,Peptidase_S9
SRR25158347_k127_2303690_2	1506583.JQJY01000005_gene2266	8.345e-10	69.0	COG1388@1|root,COG2755@1|root,COG1388@2|Bacteria,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,1I0ZE@117743|Flavobacteriia,2NSXH@237|Flavobacterium	976|Bacteroidetes	EM	Peptidoglycan-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
SRR25158347_k127_2309145_1	1227268.HMPREF1552_00601	2.533e-07	60.0	COG0642@1|root,COG2770@1|root,COG0642@2|Bacteria,COG2770@2|Bacteria,378SW@32066|Fusobacteria	32066|Fusobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_2309145_0	765952.PUV_19070	1.087e-07	60.0	COG0526@1|root,COG0526@2|Bacteria,2JFZU@204428|Chlamydiae	204428|Chlamydiae	CO	Thioredoxin-like	dsbH	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	Thioredoxin_2,Thioredoxin_7
SRR25158347_k127_231411_0	1242864.D187_008792	2.269e-19	95.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158347_k127_2317724_0	794903.OPIT5_27280	1.015e-84	290.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,3K96P@414999|Opitutae	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR25158347_k127_2330746_0	1288963.ADIS_3218	1.009e-38	149.0	COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,47MBX@768503|Cytophagia	976|Bacteroidetes	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
SRR25158347_k127_2330746_1	1341181.FLJC2902T_25080	1.488e-11	78.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158347_k127_233088_1	1028801.RG1141_CH02190	3.559e-24	109.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2U864@28211|Alphaproteobacteria,4B88Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
SRR25158347_k127_233088_0	1123514.KB905899_gene889	1.554e-53	197.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	GGDEF,Na_H_Exchanger
SRR25158347_k127_2331276_0	526224.Bmur_1889	4.875e-173	559.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158347_k127_2332523_0	1125863.JAFN01000001_gene1438	0.0	1122.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SRR25158347_k127_2332523_4	926556.Echvi_0809	0.0004226	45.0	COG3547@1|root,COG3547@2|Bacteria,4NF2F@976|Bacteroidetes,47PJU@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158347_k127_2332523_1	1341151.ASZU01000010_gene1997	2.907e-238	757.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,27B55@186824|Thermoactinomycetaceae	91061|Bacilli	P	E1-E2 ATPase	copA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158347_k127_2332523_2	1122915.AUGY01000015_gene2572	7.721e-12	69.0	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4IRA4@91061|Bacilli,276PN@186822|Paenibacillaceae	91061|Bacilli	P	Copper resistance protein CopZ	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SRR25158347_k127_2332523_3	1410622.JNKY01000001_gene1325	1.825e-07	62.0	COG3209@1|root,COG3209@2|Bacteria,1UPJF@1239|Firmicutes,25HI7@186801|Clostridia,27UMV@186928|unclassified Lachnospiraceae	186801|Clostridia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_233617_1	865937.Gilli_1068	1.455e-53	195.0	COG0463@1|root,COG0463@2|Bacteria,4NRGZ@976|Bacteroidetes,1I3RI@117743|Flavobacteriia,2P7NB@244698|Gillisia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_233617_0	1392489.JPOL01000002_gene2694	1.173e-56	209.0	COG0463@1|root,COG0463@2|Bacteria,4NR1C@976|Bacteroidetes,1IJXZ@117743|Flavobacteriia,2XKG5@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_2336968_0	1128427.KB904821_gene2644	3.235e-73	271.0	COG4191@1|root,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
SRR25158347_k127_234248_1	449447.MAE_42710	1.789e-29	131.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1GBYD@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase
SRR25158347_k127_234248_0	65393.PCC7424_3209	9.154e-33	132.0	COG2852@1|root,COG2852@2|Bacteria,1G6SC@1117|Cyanobacteria,3KIUM@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158347_k127_2346124_0	394503.Ccel_2338	1.198e-18	95.0	COG3170@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3170@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	1.1.3.9,3.2.1.4	ko:K01179,ko:K04618,ko:K12287,ko:K12548	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R01098,R06200,R11307,R11308	RC00194	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	DUF1929,F5_F8_type_C,Glyco_hydro_64,PKD
SRR25158347_k127_2346124_1	1123035.ARLA01000025_gene1327	0.0001466	52.0	2A3X0@1|root,30SFB@2|Bacteria,4PHBC@976|Bacteroidetes,1IFUU@117743|Flavobacteriia,4C4GG@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2346274_0	313606.M23134_06970	2.182e-107	358.0	COG3568@1|root,COG3568@2|Bacteria,4NV25@976|Bacteroidetes	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158347_k127_2346407_2	1304883.KI912532_gene3180	3.69e-10	67.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KVHP@206389|Rhodocyclales	206389|Rhodocyclales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_2346407_0	933262.AXAM01000056_gene3187	1.155e-67	240.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2MJP9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158347_k127_2346407_1	323259.Mhun_1505	2.767e-38	149.0	COG0631@1|root,arCOG05302@2157|Archaea,2XUZA@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM Protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	FHA,PP2C,PP2C_2
SRR25158347_k127_2346460_0	1121007.AUML01000024_gene322	3.352e-44	168.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2YH2K@290174|Aquimarina	976|Bacteroidetes	M	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_2350451_0	572544.Ilyop_1609	2.657e-26	115.0	2EYYJ@1|root,33S5A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2350451_1	344747.PM8797T_20648	2.057e-24	106.0	COG0288@1|root,COG0659@1|root,COG0288@2|Bacteria,COG0659@2|Bacteria,2IY7T@203682|Planctomycetes	203682|Planctomycetes	P	COG0659 Sulfate permease and related transporters (MFS	-	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,Sulfate_transp
SRR25158347_k127_2350451_2	196164.23494620	2.21e-06	49.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,22KAX@1653|Corynebacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158347_k127_2355582_1	192952.MM_2881	4.906e-22	97.0	COG0642@1|root,arCOG02358@2157|Archaea,arCOG06193@2157|Archaea,2XVY8@28890|Euryarchaeota,2NBKR@224756|Methanomicrobia	28890|Euryarchaeota	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,sCache_3_3
SRR25158347_k127_2355582_2	1121007.AUML01000006_gene3032	3.398e-21	97.0	COG0745@1|root,COG0745@2|Bacteria,4NV35@976|Bacteroidetes,1I3HP@117743|Flavobacteriia,2YJIM@290174|Aquimarina	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_2355582_0	1121090.KB894701_gene3342	2.018e-28	121.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1ZGDP@1386|Bacillus	91061|Bacilli	D	septum formation protein Maf	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158347_k127_2357490_0	1288963.ADIS_1164	2.519e-98	331.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,47NJH@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158347_k127_2357490_1	483219.LILAB_29395	3.317e-54	195.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria,42ZA2@68525|delta/epsilon subdivisions,2X2MN@28221|Deltaproteobacteria,2YUIW@29|Myxococcales	28221|Deltaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158347_k127_2359520_1	1305732.JAGG01000001_gene166	4.294e-48	177.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4FMRD@85023|Microbacteriaceae	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158347_k127_2359520_0	1128421.JAGA01000003_gene3456	6.249e-70	241.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158347_k127_2360289_0	159087.Daro_4059	1.452e-143	466.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria,2VZKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SRR25158347_k127_2360578_0	383372.Rcas_3859	9.036e-103	345.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
SRR25158347_k127_2360578_1	641524.ADICYQ_4554	3.564e-44	166.0	COG4251@1|root,COG4251@2|Bacteria,4NHEM@976|Bacteroidetes,47QEB@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154,HATPase_c,HisKA,PAS,PAS_9
SRR25158347_k127_2361949_3	1003195.SCAT_0272	0.0008026	49.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria	201174|Actinobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158347_k127_2361949_0	1296416.JACB01000004_gene1187	6.52e-52	189.0	COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,1I1FG@117743|Flavobacteriia,2YI80@290174|Aquimarina	976|Bacteroidetes	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
SRR25158347_k127_2361949_1	153721.MYP_4624	5.611e-25	107.0	2DYTW@1|root,34B31@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2361949_2	926562.Oweho_2295	2.101e-08	55.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,1I391@117743|Flavobacteriia,2PBVY@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158347_k127_236217_0	96561.Dole_1969	3.966e-41	164.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria,2MKB4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_236217_1	1250006.JHZZ01000001_gene524	8.035e-14	75.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes,1I1D2@117743|Flavobacteriia,3VVJK@52959|Polaribacter	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158347_k127_236965_0	1487953.JMKF01000014_gene6219	1.129e-56	213.0	COG2202@1|root,COG3829@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158347_k127_236965_2	671143.DAMO_2049	5.48e-39	152.0	COG3587@1|root,COG3587@2|Bacteria,2NQJX@2323|unclassified Bacteria	2|Bacteria	V	Type III restriction enzyme, res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
SRR25158347_k127_236965_3	195250.CM001776_gene1349	2.478e-09	65.0	COG3587@1|root,COG3587@2|Bacteria,1G4HJ@1117|Cyanobacteria,1H06R@1129|Synechococcus	1117|Cyanobacteria	V	Type III restriction enzyme res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
SRR25158347_k127_236965_1	644282.Deba_1598	5.494e-49	176.0	COG3587@1|root,COG3587@2|Bacteria,1QUSI@1224|Proteobacteria,42QF0@68525|delta/epsilon subdivisions,2WKW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Type III restriction enzyme, res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
SRR25158347_k127_2370877_0	471854.Dfer_3356	1.842e-21	100.0	2AJJ1@1|root,31A5V@2|Bacteria,4NRYB@976|Bacteroidetes,47QQT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2370877_1	1121874.KB892377_gene1044	2.898e-09	66.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_2370963_0	1173022.Cri9333_1599	6.681e-136	445.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_2370963_1	667015.Bacsa_1838	4.26e-08	57.0	COG2208@1|root,COG4753@1|root,COG2208@2|Bacteria,COG4753@2|Bacteria,4PM3Q@976|Bacteroidetes,2G2UW@200643|Bacteroidia,4AW55@815|Bacteroidaceae	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
SRR25158347_k127_2372685_0	1168034.FH5T_17735	8.242e-62	222.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,4P2BP@976|Bacteroidetes	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_2372685_1	1121373.KB903624_gene2442	7.016e-25	105.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,47RWJ@768503|Cytophagia	976|Bacteroidetes	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
SRR25158347_k127_2372685_2	1121405.dsmv_0059	2.217e-11	72.0	COG1051@1|root,COG1057@1|root,COG1051@2|Bacteria,COG1057@2|Bacteria,1QTT4@1224|Proteobacteria,42SX4@68525|delta/epsilon subdivisions,2WPWK@28221|Deltaproteobacteria,2MP07@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158347_k127_2375031_2	1184267.A11Q_1510	3.595e-10	63.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2MTQJ@213481|Bdellovibrionales,2WM3C@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Polysulphide reductase	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SRR25158347_k127_2375031_0	765869.BDW_05540	1.398e-239	775.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2MTN3@213481|Bdellovibrionales,2WKHA@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	iron-sulfur binding	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_2375031_1	1232410.KI421425_gene1566	2.253e-26	109.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2376694_0	1184267.A11Q_1675	6.216e-140	450.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2MSUI@213481|Bdellovibrionales,2WJQ2@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_2376694_1	4096.XP_009770716.1	4.446e-05	49.0	COG0265@1|root,KOG1320@2759|Eukaryota,37JRX@33090|Viridiplantae,3GEAY@35493|Streptophyta	35493|Streptophyta	O	Protease Do-like 9	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009507,GO:0009536,GO:0016787,GO:0017171,GO:0019538,GO:0031974,GO:0031981,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070011,GO:0070013,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_2377617_1	335543.Sfum_0414	8.634e-09	58.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,2MS1G@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	HRDC domain	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158347_k127_2377617_0	338966.Ppro_1153	5.67e-168	542.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158347_k127_2381409_0	338963.Pcar_1613	8.869e-111	368.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158347_k127_2385623_0	631362.Thi970DRAFT_03968	1.998e-213	671.0	COG0714@1|root,COG0714@2|Bacteria,1MXQ2@1224|Proteobacteria,1S1RQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
SRR25158347_k127_2386405_0	697282.Mettu_1451	7.712e-116	377.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XEVV@135618|Methylococcales	1236|Gammaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158347_k127_2386405_1	1122207.MUS1_02500	1.638e-80	272.0	COG0512@1|root,COG0512@2|Bacteria,1MXP3@1224|Proteobacteria,1RRY2@1236|Gammaproteobacteria,1XHS0@135619|Oceanospirillales	135619|Oceanospirillales	EH	anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158347_k127_2386405_2	1173027.Mic7113_0733	5.414e-22	102.0	COG0745@1|root,COG2208@1|root,COG3452@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,SpoIIE
SRR25158347_k127_2399004_0	865861.AZSU01000002_gene2788	3.833e-06	55.0	COG1853@1|root,COG1853@2|Bacteria,1V4IU@1239|Firmicutes,25B2Z@186801|Clostridia,36JGZ@31979|Clostridiaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158347_k127_2399582_0	59919.PMM1472	8.682e-40	155.0	COG0161@1|root,COG0161@2|Bacteria,1G1QE@1117|Cyanobacteria,1MKI4@1212|Prochloraceae	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_2400496_2	1177928.TH2_09574	3.668e-15	80.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JPVE@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,MASE1,Response_reg
SRR25158347_k127_2400496_1	933262.AXAM01000030_gene817	9.93e-74	265.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WJNC@28221|Deltaproteobacteria,2MHT3@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	Anthranilate synthase component I domain protein	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
SRR25158347_k127_2400496_0	1304885.AUEY01000002_gene321	3.414e-90	300.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,2MI3X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158347_k127_2402372_0	1125863.JAFN01000001_gene1438	0.0	1181.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SRR25158347_k127_2402372_1	1125863.JAFN01000001_gene1439	5.689e-96	327.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
SRR25158347_k127_2403175_1	660470.Theba_2574	4.068e-26	111.0	COG1916@1|root,COG1916@2|Bacteria	2|Bacteria	-	-	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
SRR25158347_k127_2403175_0	641107.CDLVIII_5035	2.798e-33	134.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia,36I61@31979|Clostridiaceae	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
SRR25158347_k127_2406590_0	221027.JO40_03300	5.719e-88	299.0	COG0587@1|root,COG0587@2|Bacteria,2J5B5@203691|Spirochaetes	203691|Spirochaetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158347_k127_2407378_1	1120953.AUBH01000001_gene957	1.687e-68	240.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,466QH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRR25158347_k127_2407378_0	443152.MDG893_06985	7.054e-126	418.0	COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,1RSDG@1236|Gammaproteobacteria,463Z8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3336,Patatin
SRR25158347_k127_2408265_1	530564.Psta_3614	5.006e-14	80.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158347_k127_2408265_0	768670.Calni_0592	1.539e-168	539.0	COG0112@1|root,COG0112@2|Bacteria,2GERI@200930|Deferribacteres	200930|Deferribacteres	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158347_k127_2409928_0	647113.Metok_0261	4.038e-09	66.0	COG2129@1|root,arCOG01145@2157|Archaea,2XXMZ@28890|Euryarchaeota,23QWK@183939|Methanococci	183939|Methanococci	S	PFAM Metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158347_k127_2409928_1	944480.ATUV01000001_gene833	9.947e-09	58.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2WJ62@28221|Deltaproteobacteria,2M6AF@213113|Desulfurellales	28221|Deltaproteobacteria	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
SRR25158347_k127_2410282_1	1121931.AUHG01000011_gene1653	5.563e-93	306.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158347_k127_2410282_0	411154.GFO_2869	7.784e-127	407.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1HXZB@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158347_k127_2410708_1	1124780.ANNU01000017_gene1922	2.093e-34	149.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,4NFC3@976|Bacteroidetes,47XEH@768503|Cytophagia	976|Bacteroidetes	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
SRR25158347_k127_2410708_2	1202532.FF52_04260	7.184e-20	104.0	COG2201@1|root,COG2201@2|Bacteria,4NNR3@976|Bacteroidetes,1I346@117743|Flavobacteriia,2NUVK@237|Flavobacterium	976|Bacteroidetes	NT	methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
SRR25158347_k127_2410708_0	506534.Rhein_2530	1.417e-35	147.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,1X0A9@135613|Chromatiales	135613|Chromatiales	E	Aromatic amino acid lyase	-	-	4.3.1.23	ko:K10774	ko00350,map00350	-	R00737	RC00361	ko00000,ko00001,ko01000	-	-	-	Lyase_aromatic
SRR25158347_k127_2413152_0	211165.AJLN01000081_gene1022	1.588e-43	162.0	COG1253@1|root,COG1253@2|Bacteria,1G2HK@1117|Cyanobacteria,1JKS7@1189|Stigonemataceae	1117|Cyanobacteria	S	Domain of unknown function DUF21	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
SRR25158347_k127_2413152_1	338969.Rfer_3358	7.944e-22	104.0	COG1075@1|root,COG1075@2|Bacteria,1NB6J@1224|Proteobacteria,2VJTN@28216|Betaproteobacteria,4ABWK@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha beta hydrolase fold	lip	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158347_k127_2414289_0	722419.PH505_bi00100	2.019e-06	60.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,2Q0M0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Sensory box sensor histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,TarH
SRR25158347_k127_2417119_2	1387312.BAUS01000001_gene1303	4.182e-21	102.0	COG0189@1|root,COG0189@2|Bacteria,1NNP5@1224|Proteobacteria,2VIF2@28216|Betaproteobacteria	28216|Betaproteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2417119_0	1117379.BABA_10011	3.451e-90	305.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4HTSS@91061|Bacilli,1ZE1D@1386|Bacillus	91061|Bacilli	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158347_k127_2417119_1	932678.THERU_02840	6.759e-45	166.0	COG0504@1|root,COG0504@2|Bacteria,2G3KJ@200783|Aquificae	200783|Aquificae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158347_k127_2421998_0	1254432.SCE1572_11060	4.064e-94	320.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2
SRR25158347_k127_242251_1	266265.Bxe_A0215	1.875e-12	70.0	2DNWH@1|root,32ZJ0@2|Bacteria,1NBJK@1224|Proteobacteria,2VYZD@28216|Betaproteobacteria,1KB19@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031
SRR25158347_k127_242251_0	33876.JNXY01000031_gene3059	1.31e-43	164.0	COG2267@1|root,COG2267@2|Bacteria,2GIVB@201174|Actinobacteria,4D8GX@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158347_k127_2424535_0	1499967.BAYZ01000095_gene4114	3.405e-103	355.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_2425528_2	883.DvMF_1898	1.635e-36	140.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,42QFJ@68525|delta/epsilon subdivisions,2WM97@28221|Deltaproteobacteria,2M957@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.20	ko:K01630	ko00053,map00053	-	R02754,R03277	RC00307,RC00435	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158347_k127_2425528_3	1307759.JOMJ01000003_gene805	7.723e-08	56.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2M9D7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158347_k127_2425528_1	1288494.EBAPG3_10090	2.911e-46	174.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,374P8@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158347_k127_2425528_0	631362.Thi970DRAFT_02573	3.089e-59	211.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Ogr_Delta
SRR25158347_k127_2426879_0	1121918.ARWE01000001_gene1323	7.22e-08	64.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HATPase_c,HisKA,dCache_1
SRR25158347_k127_2437814_0	945713.IALB_1893	4.136e-07	58.0	COG3117@1|root,COG3117@2|Bacteria	2|Bacteria	P	lipopolysaccharide transmembrane transporter activity	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SRR25158347_k127_2440257_1	1391646.AVSU01000138_gene200	5.037e-12	67.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158347_k127_2440257_0	903818.KI912268_gene2215	2.828e-77	273.0	COG0840@1|root,COG0840@2|Bacteria,3Y4VY@57723|Acidobacteria	57723|Acidobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
SRR25158347_k127_2441061_0	880073.Calab_1570	6.822e-05	54.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	sap	GO:0003674,GO:0005198,GO:0005199,GO:0005575,GO:0005623,GO:0008150,GO:0009273,GO:0009987,GO:0030115,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944	3.2.1.1,3.5.1.28	ko:K01176,ko:K01448	ko00500,ko01100,ko01503,ko04973,map00500,map01100,map01503,map04973	M00727	R02108,R02112,R04112,R11262	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	GH13	-	Amidase_3,Big_2,Big_5,LysM,Peptidase_M23,SLH
SRR25158347_k127_2444721_2	1123376.AUIU01000016_gene283	8.019e-13	68.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158347_k127_2444721_1	768670.Calni_0859	3.038e-58	216.0	COG1520@1|root,COG3391@1|root,COG4249@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158347_k127_2444721_0	1123376.AUIU01000016_gene283	1.533e-163	543.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158347_k127_2450371_1	305900.GV64_00325	2.941e-28	121.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XH93@135619|Oceanospirillales	135619|Oceanospirillales	J	Elongation factor P--(R)-beta-lysine ligase	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
SRR25158347_k127_2450371_0	215803.DB30_3447	9.895e-84	287.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_2452653_0	204536.SULAZ_1547	4.541e-06	59.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SRR25158347_k127_2452653_1	1123504.JQKD01000034_gene2738	0.0003013	51.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2VU4E@28216|Betaproteobacteria,4AFA9@80864|Comamonadaceae	28216|Betaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158347_k127_245314_1	1095769.CAHF01000006_gene1757	1.877e-22	108.0	COG1075@1|root,COG1075@2|Bacteria,1NB6J@1224|Proteobacteria,2VJTN@28216|Betaproteobacteria,473NC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	alpha/beta hydrolase fold	lip	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158347_k127_245314_0	269798.CHU_2793	4.083e-27	124.0	COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,47Q84@768503|Cytophagia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
SRR25158347_k127_2456268_0	247490.KSU1_B0356	1.267e-07	58.0	COG1669@1|root,COG1669@2|Bacteria,2J4QF@203682|Planctomycetes	203682|Planctomycetes	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158347_k127_245793_1	1116472.MGMO_94c00260	1.985e-56	201.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria	1224|Proteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase
SRR25158347_k127_245793_0	1408164.MOLA814_00702	5.137e-76	259.0	COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158347_k127_2461157_1	1304888.ATWF01000002_gene440	3.924e-28	127.0	COG4591@1|root,COG4591@2|Bacteria,2GEN3@200930|Deferribacteres	200930|Deferribacteres	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158347_k127_2461157_0	1158338.JNLJ01000001_gene631	1.62e-35	143.0	COG0461@1|root,COG0461@2|Bacteria,2G4DW@200783|Aquificae	200783|Aquificae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158347_k127_2461157_2	1419583.V466_09410	5.882e-19	88.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1YQ8Y@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
SRR25158347_k127_2462101_0	314285.KT71_17656	3.315e-76	261.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1JAET@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158347_k127_2464965_0	118168.MC7420_3587	2.438e-43	175.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158347_k127_2468397_0	179408.Osc7112_5077	6.28e-71	254.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GC6Z@1117|Cyanobacteria,1H6Y9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_247144_0	868595.Desca_0272	2.293e-159	514.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,260GB@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158347_k127_247144_1	1220589.CD32_13545	3.359e-37	149.0	COG1423@1|root,COG1423@2|Bacteria,1UXEU@1239|Firmicutes,4HAFI@91061|Bacilli,3IZ99@400634|Lysinibacillus	91061|Bacilli	L	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
SRR25158347_k127_247144_2	244447.XP_008335387.1	3.485e-12	72.0	KOG2242@1|root,KOG2242@2759|Eukaryota,38FNX@33154|Opisthokonta,3BD0H@33208|Metazoa,3CRCQ@33213|Bilateria,481JN@7711|Chordata,495WA@7742|Vertebrata,49WYP@7898|Actinopterygii	33208|Metazoa	A	Heterogeneous nuclear ribonucleoprotein	HNRNPU	GO:0000122,GO:0000166,GO:0000228,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0000775,GO:0000776,GO:0000803,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0000993,GO:0001012,GO:0001067,GO:0001085,GO:0001091,GO:0001097,GO:0001098,GO:0001099,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003697,GO:0003712,GO:0003714,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003730,GO:0003779,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005697,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0005874,GO:0005876,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006403,GO:0006725,GO:0006807,GO:0007088,GO:0007275,GO:0007346,GO:0007507,GO:0007549,GO:0007623,GO:0008092,GO:0008104,GO:0008134,GO:0008143,GO:0008144,GO:0008150,GO:0008152,GO:0008187,GO:0008284,GO:0008380,GO:0009048,GO:0009410,GO:0009719,GO:0009725,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009986,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010639,GO:0010911,GO:0010912,GO:0014070,GO:0014706,GO:0015630,GO:0016070,GO:0016071,GO:0016363,GO:0016604,GO:0016607,GO:0017069,GO:0017076,GO:0017130,GO:0019219,GO:0019220,GO:0019222,GO:0019899,GO:0030154,GO:0030496,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031490,GO:0031960,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032501,GO:0032502,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032781,GO:0032784,GO:0032785,GO:0032870,GO:0032879,GO:0032886,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033365,GO:0033673,GO:0033993,GO:0034046,GO:0034097,GO:0034243,GO:0034244,GO:0034399,GO:0034504,GO:0034613,GO:0034641,GO:0035051,GO:0035372,GO:0035639,GO:0035690,GO:0035770,GO:0036002,GO:0036094,GO:0036464,GO:0040029,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042493,GO:0042692,GO:0042802,GO:0043021,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043462,GO:0043484,GO:0043487,GO:0043488,GO:0043489,GO:0043549,GO:0043565,GO:0044087,GO:0044092,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044380,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045185,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045600,GO:0045787,GO:0045840,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0046483,GO:0048024,GO:0048255,GO:0048468,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0050684,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051233,GO:0051235,GO:0051252,GO:0051253,GO:0051254,GO:0051336,GO:0051338,GO:0051345,GO:0051348,GO:0051384,GO:0051457,GO:0051493,GO:0051641,GO:0051651,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0051987,GO:0051988,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0060236,GO:0060255,GO:0060341,GO:0060537,GO:0061013,GO:0061061,GO:0062033,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070034,GO:0070063,GO:0070507,GO:0070717,GO:0070727,GO:0070887,GO:0070934,GO:0070937,GO:0071013,GO:0071310,GO:0071345,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0072091,GO:0072359,GO:0072595,GO:0072686,GO:0072698,GO:0080090,GO:0090068,GO:0090169,GO:0090224,GO:0090235,GO:0090304,GO:0090335,GO:0090336,GO:0097159,GO:0097327,GO:0097367,GO:0098577,GO:0098687,GO:0099080,GO:0099081,GO:0099122,GO:0099512,GO:0099513,GO:0140110,GO:1901265,GO:1901360,GO:1901363,GO:1901654,GO:1901655,GO:1901673,GO:1901700,GO:1901701,GO:1902115,GO:1902275,GO:1902369,GO:1902373,GO:1902423,GO:1902425,GO:1902494,GO:1902679,GO:1902680,GO:1902889,GO:1903311,GO:1903312,GO:1903506,GO:1903507,GO:1903508,GO:1904356,GO:1904357,GO:1990023,GO:1990280,GO:1990498,GO:1990823,GO:1990830,GO:1990837,GO:1990841,GO:1990845,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2000371,GO:2000373,GO:2000648,GO:2000736,GO:2000737,GO:2001141,GO:2001251,GO:2001252	-	ko:K12888,ko:K15047,ko:K15698	ko03040,ko05164,map03040,map05164	-	-	-	ko00000,ko00001,ko03041,ko04121	-	-	-	AAA_33,SAP,SPRY
SRR25158347_k127_2476943_1	10228.TriadP58866	5.678e-12	76.0	COG0457@1|root,KOG1840@2759|Eukaryota,3A3MA@33154|Opisthokonta,3BSDD@33208|Metazoa	33208|Metazoa	Z	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF294,Death,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
SRR25158347_k127_2476943_0	553218.CAMRE0001_2601	2.449e-84	291.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2YMQF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158347_k127_247773_1	768704.Desmer_2914	1.886e-81	295.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_247773_0	1184267.A11Q_1776	5.504e-91	309.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2MSNE@213481|Bdellovibrionales,2WKPM@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_2481605_1	118005.AWNK01000001_gene1936	3.418e-87	290.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	capI	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158347_k127_2481605_0	228410.NE2276	9.826e-106	347.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,37272@32003|Nitrosomonadales	28216|Betaproteobacteria	M	UDP binding domain	wbpO	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158347_k127_2485820_0	909663.KI867151_gene3015	1.811e-167	534.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2MQ5Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158347_k127_2487238_1	1123278.KB893548_gene4728	2.763e-19	91.0	COG2442@1|root,COG2442@2|Bacteria,4NZ3D@976|Bacteroidetes,47X60@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158347_k127_2487238_0	429009.Adeg_0279	7.317e-22	98.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2487238_2	765952.PUV_10220	6.964e-08	54.0	COG0812@1|root,COG0812@2|Bacteria,2JFHG@204428|Chlamydiae	204428|Chlamydiae	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158347_k127_2494174_0	1121904.ARBP01000015_gene166	4.873e-16	79.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,47K60@768503|Cytophagia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
SRR25158347_k127_2494360_1	756067.MicvaDRAFT_4983	1.951e-30	122.0	COG2192@1|root,COG2192@2|Bacteria,1G1FV@1117|Cyanobacteria,1H9E9@1150|Oscillatoriales	1117|Cyanobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158347_k127_2494360_2	335543.Sfum_1483	1.473e-09	67.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MRYE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158347_k127_2494360_0	985255.APHJ01000025_gene1050	8.346e-48	178.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1HXBP@117743|Flavobacteriia,2P5US@244698|Gillisia	976|Bacteroidetes	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SRR25158347_k127_2497636_1	317619.ANKN01000126_gene3251	7.357e-51	185.0	COG1216@1|root,COG1216@2|Bacteria,1G48C@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2497636_0	1121090.KB894689_gene294	1.663e-75	258.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus	91061|Bacilli	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158347_k127_2499978_2	395961.Cyan7425_1898	4.406e-06	51.0	COG1032@1|root,COG1032@2|Bacteria,1G4FG@1117|Cyanobacteria,3KIA5@43988|Cyanothece	1117|Cyanobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158347_k127_2499978_1	1218103.CIN01S_09_02400	5.692e-83	282.0	COG5285@1|root,COG5285@2|Bacteria,4NIIV@976|Bacteroidetes,1HZHD@117743|Flavobacteriia,3ZPMY@59732|Chryseobacterium	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158347_k127_2499978_0	945713.IALB_2739	7.963e-114	372.0	COG0114@1|root,COG0114@2|Bacteria	2|Bacteria	C	fumarate hydratase activity	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158347_k127_2499997_4	1121403.AUCV01000047_gene1053	1.025e-06	56.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,42RTP@68525|delta/epsilon subdivisions,2WN9M@28221|Deltaproteobacteria,2MKCH@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_8,Response_reg,SpoIIE
SRR25158347_k127_2499997_1	1291050.JAGE01000001_gene2069	1.315e-79	274.0	COG0152@1|root,COG0152@2|Bacteria,1VTBC@1239|Firmicutes,24ZTC@186801|Clostridia,3WH16@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158347_k127_2499997_3	240292.Ava_0406	2.101e-20	93.0	COG1828@1|root,COG1828@2|Bacteria,1G7S5@1117|Cyanobacteria,1HNVI@1161|Nostocales	1117|Cyanobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158347_k127_2499997_2	1471459.JFLJ01000113_gene322	2.36e-70	244.0	COG0047@1|root,COG0047@2|Bacteria,1G18Q@1117|Cyanobacteria,1MM35@1212|Prochloraceae	1117|Cyanobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158347_k127_2499997_0	1347342.BN863_35650	6.452e-91	308.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1HYK5@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158347_k127_2501441_0	391625.PPSIR1_28388	1.606e-50	187.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
SRR25158347_k127_2501441_1	1278073.MYSTI_00788	0.0006856	52.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	7TMR-DISM_7TM,HAMP,MCPsignal
SRR25158347_k127_2505022_0	502025.Hoch_0745	3.388e-131	428.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42SZ0@68525|delta/epsilon subdivisions,2WPIR@28221|Deltaproteobacteria,2Z0J2@29|Myxococcales	28221|Deltaproteobacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
SRR25158347_k127_2505430_0	443254.Marpi_1936	0.0001097	54.0	COG4191@1|root,COG4191@2|Bacteria,2GCWT@200918|Thermotogae	200918|Thermotogae	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_2507148_0	1415778.JQMM01000001_gene1640	5.789e-66	228.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1J4KB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SRR25158347_k127_2507148_1	743722.Sph21_3747	1.428e-34	136.0	COG2146@1|root,COG2146@2|Bacteria,4NQQ8@976|Bacteroidetes,1ISS2@117747|Sphingobacteriia	976|Bacteroidetes	P	Nitrite reductase	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
SRR25158347_k127_2507148_2	367737.Abu_0365	1.468e-22	102.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2YNRA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
SRR25158347_k127_2509223_1	1209072.ALBT01000035_gene1407	1.35e-60	216.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1FFT5@10|Cellvibrio	1236|Gammaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
SRR25158347_k127_2509223_0	765869.BDW_09465	3.086e-177	565.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2MSPA@213481|Bdellovibrionales,2WM27@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
SRR25158347_k127_2509407_2	882.DVU_0353	3.089e-21	94.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42NQF@68525|delta/epsilon subdivisions,2WKU3@28221|Deltaproteobacteria,2MAHI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
SRR25158347_k127_2509407_1	146891.A9601_14251	1.096e-49	184.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_2509407_0	1121403.AUCV01000010_gene1363	1.199e-80	275.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MDC@68525|delta/epsilon subdivisions,2WJM7@28221|Deltaproteobacteria,2MHWR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102,2.6.1.109	ko:K13010,ko:K19715	ko00520,map00520	-	R10460,R11395	RC00006,RC00160,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158347_k127_2510427_0	661478.OP10G_4041	4.098e-36	141.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
SRR25158347_k127_2510427_1	264462.Bd2107	2.677e-17	92.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria,1QSA7@1224|Proteobacteria,42T4Y@68525|delta/epsilon subdivisions,2MTAB@213481|Bdellovibrionales,2WPNT@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Thiol disulfide interchange protein dsbA	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4,VKOR
SRR25158347_k127_2510951_0	1121382.JQKG01000030_gene2746	5.43e-86	295.0	COG0469@1|root,COG0469@2|Bacteria,1WJAC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158347_k127_2513170_2	867900.Celly_2286	0.0008692	46.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,1F849@104264|Cellulophaga	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
SRR25158347_k127_2513170_1	1123274.KB899428_gene1852	1.734e-65	229.0	COG0664@1|root,COG0664@2|Bacteria,2J6ZR@203691|Spirochaetes	203691|Spirochaetes	K	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_2513170_0	1158345.JNLL01000001_gene175	1.893e-85	290.0	COG0476@1|root,COG0476@2|Bacteria,2G4P8@200783|Aquificae	200783|Aquificae	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158347_k127_2513196_1	633131.TR2A62_2518	1.039e-54	198.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	3-5 exonuclease	rnd1	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
SRR25158347_k127_2513196_0	1033734.CAET01000080_gene3305	7.209e-123	408.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
SRR25158347_k127_2516234_0	1121121.KB894311_gene4282	1.446e-122	404.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HBR0@91061|Bacilli,26QBM@186822|Paenibacillaceae	91061|Bacilli	C	NADH flavin	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158347_k127_2517071_1	1123070.KB899247_gene1597	2.111e-10	68.0	2BKT6@1|root,32F9D@2|Bacteria,46XQ4@74201|Verrucomicrobia,2IWCU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2517071_0	1449338.JQLU01000005_gene3134	1.733e-40	153.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_2519664_1	198094.BA_3805	0.00011	53.0	COG1075@1|root,COG1075@2|Bacteria,1VIWR@1239|Firmicutes,4HQU4@91061|Bacilli,1ZKJQ@1386|Bacillus	91061|Bacilli	S	Lecithin:cholesterol acyltransferase	est	-	-	-	-	-	-	-	-	-	-	-	LCAT,PPC
SRR25158347_k127_2519664_0	765420.OSCT_0643	2.823e-28	130.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2519982_1	1121920.AUAU01000011_gene149	1.233e-17	87.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08162,ko:K08226,ko:K16211	-	-	-	-	ko00000,ko02000	2.A.1.2.21,2.A.1.41,2.A.2.6	-	-	MFS_1,PUCC
SRR25158347_k127_2519982_0	335543.Sfum_3738	8.596e-27	119.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,43C4U@68525|delta/epsilon subdivisions,2WMNA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRR25158347_k127_2521246_1	313612.L8106_24285	1.047e-25	107.0	COG1085@1|root,COG1085@2|Bacteria,1G1CA@1117|Cyanobacteria,1H82Z@1150|Oscillatoriales	1117|Cyanobacteria	C	galactose-1-phosphate	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf,HIT
SRR25158347_k127_2521246_0	862965.PARA_01660	1.397e-102	344.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1Y6XQ@135625|Pasteurellales	135625|Pasteurellales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158347_k127_2522860_1	333138.LQ50_20815	7.211e-51	184.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	thlA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158347_k127_2522860_0	1048983.EL17_04325	1.063e-63	237.0	COG4775@1|root,COG4775@2|Bacteria,4NMIQ@976|Bacteroidetes,47PGI@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SRR25158347_k127_2522869_1	1268240.ATFI01000007_gene431	3.744e-05	48.0	COG0863@1|root,COG0863@2|Bacteria,4NQQ1@976|Bacteroidetes,2G1PS@200643|Bacteroidia,4ARBB@815|Bacteroidaceae	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158347_k127_2522869_0	1173022.Cri9333_3706	4.145e-114	379.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_2525669_1	264462.Bd0287	4.325e-28	115.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2MSS3@213481|Bdellovibrionales,2WJUK@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
SRR25158347_k127_2525669_0	1184267.A11Q_450	1.032e-66	236.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2MUQ1@213481|Bdellovibrionales,2WN7W@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158347_k127_2525669_2	765869.BDW_01020	2.03e-16	82.0	2DR0H@1|root,339NS@2|Bacteria,1Q21V@1224|Proteobacteria,437PH@68525|delta/epsilon subdivisions,2MUAK@213481|Bdellovibrionales,2X2XV@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158347_k127_2526062_0	545694.TREPR_3151	1.955e-20	103.0	COG0642@1|root,COG0642@2|Bacteria,2JBJJ@203691|Spirochaetes	203691|Spirochaetes	T	Hybrid Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_2526685_1	1121929.KB898668_gene3300	1.383e-41	156.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,470EN@74385|Gracilibacillus	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158347_k127_2526685_0	457570.Nther_1433	1.297e-66	234.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158347_k127_2531791_1	1442598.JABW01000023_gene1483	1.666e-16	93.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2YSH2@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158347_k127_2531791_0	118173.KB235914_gene3418	3.4e-28	116.0	296N4@1|root,2ZTX9@2|Bacteria,1G6RZ@1117|Cyanobacteria,1HBVF@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM XisH protein	-	-	-	-	-	-	-	-	-	-	-	-	XisH
SRR25158347_k127_2534502_1	1242864.D187_003117	1.209e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,42VQ5@68525|delta/epsilon subdivisions,2WSX2@28221|Deltaproteobacteria,2YZU5@29|Myxococcales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158347_k127_2534502_0	118163.Ple7327_0865	5.513e-184	588.0	COG1233@1|root,COG1233@2|Bacteria,1G4AK@1117|Cyanobacteria	1117|Cyanobacteria	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158347_k127_2535759_0	870187.Thini_1614	7.877e-163	525.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,1RQDM@1236|Gammaproteobacteria,4623T@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_2536379_0	5786.XP_003289856.1	3.02e-06	60.0	2CSVJ@1|root,2RDD5@2759|Eukaryota,3XC4G@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2547559_1	1122605.KB893626_gene2453	3.413e-09	61.0	COG1231@1|root,COG1231@2|Bacteria,4NJU7@976|Bacteroidetes,1IYQ9@117747|Sphingobacteriia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158347_k127_2547559_2	1121382.JQKG01000071_gene2104	7.274e-08	57.0	COG1826@1|root,COG1826@2|Bacteria,1WKJH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158347_k127_2547559_0	1537994.JQFW01000007_gene2925	1.729e-25	117.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,4659G@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158347_k127_2551949_0	324925.Ppha_1722	1.903e-05	49.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
SRR25158347_k127_255456_0	1131269.AQVV01000006_gene435	5.445e-92	306.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158347_k127_255456_1	1485545.JQLW01000005_gene1014	1.58e-20	96.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
SRR25158347_k127_2555325_0	1008457.BAEX01000025_gene2034	5.045e-37	143.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1HWZ8@117743|Flavobacteriia,47H4D@76831|Myroides	976|Bacteroidetes	H	Pyridoxal phosphate biosynthetic protein PdxA	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158347_k127_2555325_1	1254432.SCE1572_51580	1.28e-21	100.0	COG0517@1|root,COG0517@2|Bacteria,1N68U@1224|Proteobacteria,42UEN@68525|delta/epsilon subdivisions,2X9VF@28221|Deltaproteobacteria,2YVE6@29|Myxococcales	28221|Deltaproteobacteria	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158347_k127_2556830_0	1250005.PHEL85_0466	2.629e-104	343.0	COG0596@1|root,COG0596@2|Bacteria,4NFIB@976|Bacteroidetes,1HZHK@117743|Flavobacteriia,3VWYE@52959|Polaribacter	976|Bacteroidetes	S	Alpha/beta hydrolase family	rsbQ	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158347_k127_2556830_1	1242864.D187_002458	1.262e-25	110.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2YX8P@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
SRR25158347_k127_255708_0	459349.CLOAM1842	4.398e-64	226.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
SRR25158347_k127_255708_1	1033739.CAEU01000024_gene2990	1.458e-60	224.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,4HDPA@91061|Bacilli,26FNP@186818|Planococcaceae	91061|Bacilli	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
SRR25158347_k127_2560929_0	237368.SCABRO_01504	6.029e-154	500.0	COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes	203682|Planctomycetes	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
SRR25158347_k127_2560929_1	1499967.BAYZ01000030_gene1194	1.505e-30	123.0	COG2827@1|root,COG2827@2|Bacteria,2NRAE@2323|unclassified Bacteria	2|Bacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158347_k127_2561432_0	350688.Clos_1728	9e-48	182.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,36E00@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
SRR25158347_k127_2561548_0	509191.AEDB02000073_gene1831	0.0002788	53.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WSMQ@541000|Ruminococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_2,sCache_3_3
SRR25158347_k127_2562048_0	32057.KB217478_gene5043	3.866e-140	462.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GKA7@1117|Cyanobacteria,1HQHZ@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_2562735_0	448385.sce8281	2.669e-59	212.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158347_k127_2562735_1	756067.MicvaDRAFT_1935	1.378e-33	138.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
SRR25158347_k127_256388_1	1267535.KB906767_gene2312	6.611e-47	182.0	COG1524@1|root,COG1524@2|Bacteria,3Y7AY@57723|Acidobacteria,2JKSW@204432|Acidobacteriia	204432|Acidobacteriia	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158347_k127_256388_0	573413.Spirs_1575	5.503e-146	470.0	COG1868@1|root,COG1868@2|Bacteria,2J5WR@203691|Spirochaetes	203691|Spirochaetes	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
SRR25158347_k127_256540_0	13035.Dacsa_1685	1.304e-47	186.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria	1117|Cyanobacteria	D	sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158347_k127_2573934_0	481448.Minf_2281	6.105e-159	512.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46SCB@74201|Verrucomicrobia,37G6Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	GXGXG motif	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158347_k127_2576240_2	289376.THEYE_A0199	2.695e-111	368.0	COG0451@1|root,COG0451@2|Bacteria,3J15D@40117|Nitrospirae	40117|Nitrospirae	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
SRR25158347_k127_2576240_3	1304874.JAFY01000002_gene1020	4.173e-08	65.0	2BHZM@1|root,32C47@2|Bacteria,3TBX3@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2576240_1	768670.Calni_0859	2.073e-125	428.0	COG1520@1|root,COG3391@1|root,COG4249@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158347_k127_2576240_0	292459.STH2023	1.581e-172	556.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
SRR25158347_k127_2582466_2	744872.Spica_2526	6.572e-15	87.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2JBDH@203691|Spirochaetes	2|Bacteria	KT	7TM diverse intracellular signalling	rsbW	-	2.4.1.12,3.1.3.3	ko:K00694,ko:K07315,ko:K20977	ko00500,ko01100,ko02020,ko02025,ko02026,map00500,map01100,map02020,map02025,map02026	M00820	R02889	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000,ko02022,ko03021	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	HATPase_c_2,MatE,SpoIIE
SRR25158347_k127_2582466_0	246197.MXAN_6608	1.653e-45	174.0	COG1024@1|root,COG1024@2|Bacteria,1R67S@1224|Proteobacteria,430BK@68525|delta/epsilon subdivisions,2WVNK@28221|Deltaproteobacteria,2YY2F@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_2582466_1	485918.Cpin_1180	9.548e-39	147.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1ISJH@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158347_k127_2585832_0	1458275.AZ34_11415	2.445e-55	218.0	COG1196@1|root,COG2114@1|root,COG2770@1|root,COG1196@2|Bacteria,COG2114@2|Bacteria,COG2770@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158347_k127_2588824_0	643867.Ftrac_1694	8.966e-14	73.0	COG1309@1|root,COG1309@2|Bacteria,4NMW1@976|Bacteroidetes,47Q10@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158347_k127_2590428_1	929703.KE386492_gene4458	2.024e-49	183.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47KWE@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
SRR25158347_k127_2590428_0	931276.Cspa_c03590	1.737e-51	196.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36KBS@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg,dCache_3,sCache_3_3
SRR25158347_k127_2592521_0	563040.Saut_0283	2.666e-46	178.0	COG3551@1|root,COG3754@1|root,COG3551@2|Bacteria,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	rgpF	-	-	ko:K07272	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glyco_trans_1_4,Glycos_transf_2,RgpF,Sulfotransfer_3
SRR25158347_k127_2592521_1	1173026.Glo7428_4174	4.145e-33	130.0	COG1196@1|root,COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1196@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
SRR25158347_k127_259324_0	1382359.JIAL01000001_gene2319	3.123e-20	103.0	COG2208@1|root,COG2208@2|Bacteria,3Y6AE@57723|Acidobacteria,2JKYD@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
SRR25158347_k127_2594889_3	889378.Spiaf_2108	4.99e-28	118.0	COG1815@1|root,COG1815@2|Bacteria,2J804@203691|Spirochaetes	203691|Spirochaetes	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
SRR25158347_k127_2594889_2	665571.STHERM_c09080	2.584e-54	194.0	COG1558@1|root,COG1558@2|Bacteria,2J7Q7@203691|Spirochaetes	203691|Spirochaetes	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_2594889_4	1033734.CAET01000017_gene3276	2.543e-06	54.0	COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,4HNZW@91061|Bacilli,1ZIT0@1386|Bacillus	91061|Bacilli	N	Flagellar hook-basal body	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
SRR25158347_k127_2594889_0	349521.HCH_01747	2.586e-141	456.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XIVQ@135619|Oceanospirillales	135619|Oceanospirillales	C	Aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_2594889_5	1215343.B488_05210	0.0005335	50.0	COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7RQ@28211|Alphaproteobacteria,4BAG3@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Phage lysozyme	-	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	Phage_lysozyme
SRR25158347_k127_2594889_1	1305737.JAFX01000001_gene3077	9.409e-95	321.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_2596829_2	1238182.C882_0318	1.033e-60	211.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria,2JPMR@204441|Rhodospirillales	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	ccrA	-	1.1.1.1,1.3.1.85	ko:K00001,ko:K14446	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	M00373	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_2596829_0	877418.ATWV01000004_gene1764	1.29e-121	398.0	COG1087@1|root,COG1087@2|Bacteria,2J5YD@203691|Spirochaetes	203691|Spirochaetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158347_k127_2596829_1	1049564.TevJSym_ao00420	4.348e-74	257.0	COG1043@1|root,COG1043@2|Bacteria,1QKYH@1224|Proteobacteria,1S0N9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158347_k127_259808_1	167548.EU98_1770	3.592e-06	52.0	2DP8V@1|root,33122@2|Bacteria,1G83J@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_259808_0	398512.JQKC01000013_gene1322	5.175e-264	820.0	COG2192@1|root,COG2192@2|Bacteria,1TS7M@1239|Firmicutes,2488M@186801|Clostridia,3WIV1@541000|Ruminococcaceae	186801|Clostridia	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158347_k127_2599088_0	5888.CAK64874	1.249e-08	69.0	2F3QQ@1|root,2T4Q6@2759|Eukaryota,3ZFNP@5878|Ciliophora	5888.CAK64874|-	S	Paramecium Surface Antigen Repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2599095_0	990073.ATHU01000001_gene626	4.96e-22	104.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2YNN2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158347_k127_2599095_1	1265503.KB905175_gene3946	1.162e-13	81.0	2CUHX@1|root,32SVD@2|Bacteria,1MZQ4@1224|Proteobacteria,1S8WU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
SRR25158347_k127_2600557_0	1120953.AUBH01000002_gene1500	4.15e-78	283.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,465RG@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_2607415_0	1340493.JNIF01000003_gene2617	3.556e-39	165.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158347_k127_2607415_1	877418.ATWV01000004_gene1827	2.252e-06	57.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_2608153_0	877420.ATVW01000035_gene1432	4.484e-21	100.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,27J1W@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158347_k127_2608153_1	224308.BSU07640	6.994e-17	83.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,1ZITT@1386|Bacillus	91061|Bacilli	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020	Acylphosphatase
SRR25158347_k127_2608153_2	515620.EUBELI_20378	5.848e-16	82.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,25WQR@186806|Eubacteriaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2610905_0	1125699.HMPREF9194_02314	3.527e-05	55.0	COG1196@1|root,COG1196@2|Bacteria,2J5RV@203691|Spirochaetes	203691|Spirochaetes	D	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Apolipoprotein,HTH_38
SRR25158347_k127_2614629_0	313612.L8106_21312	8.314e-109	372.0	COG3899@1|root,COG5001@1|root,COG3899@2|Bacteria,COG5001@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg
SRR25158347_k127_2616461_0	903814.ELI_3706	2.11e-26	118.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,25XB2@186806|Eubacteriaceae	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158347_k127_262039_1	1396141.BATP01000030_gene3705	2.992e-25	113.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_262039_0	574087.Acear_0687	1.316e-55	206.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,249PW@186801|Clostridia,3WBEN@53433|Halanaerobiales	186801|Clostridia	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158347_k127_262039_2	1168065.DOK_15349	5.972e-05	45.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPJY@1236|Gammaproteobacteria,1J8GS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,FMO-like,K_oxygenase,Pyr_redox_3
SRR25158347_k127_2623831_2	1150600.ADIARSV_3176	2.199e-21	108.0	29Q0T@1|root,30AZ9@2|Bacteria,4NP77@976|Bacteroidetes,1ISFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR25158347_k127_2623831_0	1150600.ADIARSV_3177	3.716e-76	285.0	COG2304@1|root,COG2304@2|Bacteria,4NKB6@976|Bacteroidetes,1IQFS@117747|Sphingobacteriia	976|Bacteroidetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
SRR25158347_k127_2623831_1	1122179.KB890414_gene1831	2.007e-37	156.0	COG0330@1|root,COG0330@2|Bacteria,4NHJA@976|Bacteroidetes	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_2623831_3	1122176.KB903598_gene4685	1.015e-09	62.0	COG4891@1|root,COG4891@2|Bacteria,4NWBU@976|Bacteroidetes	976|Bacteroidetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_2624775_1	1396.DJ87_3028	9.824e-08	64.0	COG2733@1|root,COG2733@2|Bacteria,1TS8F@1239|Firmicutes,4HC8U@91061|Bacilli,1ZCND@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158347_k127_2624775_0	767817.Desgi_2559	1.174e-115	381.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,2601G@186807|Peptococcaceae	186801|Clostridia	J	TIGRFAM Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158347_k127_2625360_4	298386.PBPRB0538	1.307e-16	84.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XTMV@135623|Vibrionales	135623|Vibrionales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c,HisKA,Response_reg
SRR25158347_k127_2625360_0	357804.Ping_2544	3.966e-71	245.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria	1224|Proteobacteria	Q	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158347_k127_2625360_2	246197.MXAN_1598	1.545e-38	158.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158347_k127_2625360_1	925409.KI911562_gene2099	7.589e-70	244.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes,1J1AE@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_2627842_0	118163.Ple7327_4324	4.165e-100	355.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GD97@1117|Cyanobacteria,3VI2Q@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,PAS_9,Pkinase,Response_reg
SRR25158347_k127_2630070_2	675813.VIB_000310	8.449e-58	204.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XSC8@135623|Vibrionales	135623|Vibrionales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158347_k127_2630070_3	857571.EA1_06896	1.377e-32	128.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,3NK60@468|Moraxellaceae	1236|Gammaproteobacteria	V	Transport permease protein	yadH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158347_k127_2630070_0	1397527.Q670_10600	1.022e-129	420.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XHIF@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_2630070_1	386456.JQKN01000010_gene705	6.464e-62	223.0	COG0121@1|root,arCOG07614@1|root,arCOG03639@2157|Archaea,arCOG07614@2157|Archaea,2XXMS@28890|Euryarchaeota,23P8N@183925|Methanobacteria	183925|Methanobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
SRR25158347_k127_2630070_4	1341151.ASZU01000008_gene1570	1.14e-05	47.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,27BJV@186824|Thermoactinomycetaceae	91061|Bacilli	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_2630323_0	656519.Halsa_0447	1.801e-11	76.0	COG1452@1|root,COG1452@2|Bacteria,1VJ64@1239|Firmicutes,24R8M@186801|Clostridia,3WAWE@53433|Halanaerobiales	186801|Clostridia	M	Organic solvent tolerance protein OstA	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SRR25158347_k127_2630599_0	243090.RB5618	1.241e-25	107.0	COG2314@1|root,COG2314@2|Bacteria,2IZQ4@203682|Planctomycetes	203682|Planctomycetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
SRR25158347_k127_2634873_0	1379698.RBG1_1C00001G1895	7.867e-14	78.0	COG0438@1|root,COG0438@2|Bacteria,2NQAY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2635912_1	273068.TTE0275	2.265e-07	54.0	COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,24ANR@186801|Clostridia,42FD7@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_2635912_0	1424334.W822_03745	4.201e-48	178.0	COG3173@1|root,COG3173@2|Bacteria,1MY0Y@1224|Proteobacteria,2VUX6@28216|Betaproteobacteria,3T8RQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_2641903_0	1239415.CM001837_gene1574	1.838e-245	764.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1HY1T@117743|Flavobacteriia,37DZD@326319|Dokdonia	976|Bacteroidetes	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rieske
SRR25158347_k127_2643024_0	211165.AJLN01000120_gene801	1.3e-80	280.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,1JHAR@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_2643875_1	1033737.CAEV01000074_gene455	2.52e-29	122.0	COG0454@1|root,COG0456@2|Bacteria,1VFVQ@1239|Firmicutes,25H0A@186801|Clostridia,36V6S@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_2643875_0	1337093.MBE-LCI_1696	5.757e-34	142.0	COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,2TVGQ@28211|Alphaproteobacteria,2P7VD@245186|Loktanella	28211|Alphaproteobacteria	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_2649548_0	621372.ACIH01000163_gene3488	0.0001355	54.0	COG2972@1|root,COG2972@2|Bacteria,1UUZB@1239|Firmicutes,4I7DR@91061|Bacilli,26WGX@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
SRR25158347_k127_2652013_0	347834.RHE_CH00765	9.32e-40	159.0	COG0392@1|root,COG0392@2|Bacteria,1PPT0@1224|Proteobacteria,2V2VU@28211|Alphaproteobacteria,4BJQP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158347_k127_2652013_1	948565.AFFP02000008_gene1717	0.0007869	50.0	COG2378@1|root,COG2378@2|Bacteria,1R65H@1224|Proteobacteria,1S63H@1236|Gammaproteobacteria,1Y8UX@135625|Pasteurellales	135625|Pasteurellales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158347_k127_2659807_0	1121448.DGI_0433	8.378e-10	71.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M8BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158347_k127_2660242_0	796940.HMPREF9628_01001	2.94e-127	417.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,25S4K@186804|Peptostreptococcaceae	186801|Clostridia	NU	ATP synthase alpha/beta family, beta-barrel domain	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158347_k127_2663086_0	56107.Cylst_2170	1.023e-205	657.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GKA7@1117|Cyanobacteria,1HQHZ@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_2664845_0	1121935.AQXX01000073_gene300	4.543e-97	328.0	COG0738@1|root,COG0738@2|Bacteria,1QX0S@1224|Proteobacteria,1T32Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158347_k127_2664845_1	1380408.AVGH01000039_gene2265	3.288e-54	201.0	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,21VB0@150247|Anoxybacillus	91061|Bacilli	S	Patatin-like phospholipase	ylbK	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158347_k127_2665215_1	945713.IALB_1028	5.605e-24	104.0	28KFX@1|root,2ZA1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2665215_2	189426.PODO_09580	2.199e-09	67.0	COG1476@1|root,COG1476@2|Bacteria,1V2KY@1239|Firmicutes,4HMC3@91061|Bacilli,26TUG@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158347_k127_2665215_0	1492737.FEM08_30180	3.189e-54	198.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia,2NSRQ@237|Flavobacterium	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158347_k127_2666777_0	1121441.AUCX01000023_gene1813	5.999e-16	83.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R6F@68525|delta/epsilon subdivisions,2WN2B@28221|Deltaproteobacteria,2M95Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
SRR25158347_k127_2672540_0	526224.Bmur_1613	4.942e-138	458.0	COG1256@1|root,COG1256@2|Bacteria,2J5TQ@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,Flg_bbr_C
SRR25158347_k127_2672540_1	1480694.DC28_02580	4.014e-62	229.0	COG1344@1|root,COG1344@2|Bacteria,2J6BJ@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar hook-associated protein 3	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
SRR25158347_k127_26760_0	1123279.ATUS01000001_gene805	2.625e-147	481.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1S1M2@1236|Gammaproteobacteria,1J5J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2676044_0	317936.Nos7107_1366	1.304e-121	418.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	4.6.1.1	ko:K01768,ko:K07216	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,PAS_9,Pkinase,Response_reg
SRR25158347_k127_2680210_1	673862.BABL1_818	2.931e-17	86.0	COG4974@1|root,COG4974@2|Bacteria,1R43B@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR25158347_k127_2680210_0	887062.HGR_06411	3.384e-23	102.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2VVJM@28216|Betaproteobacteria,4AEUN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158347_k127_2680942_0	111781.Lepto7376_4112	2.569e-73	262.0	COG2114@1|root,COG2114@2|Bacteria,1FZXP@1117|Cyanobacteria,1H988@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768,ko:K03320	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02000	1.A.11	-	-	DUF3365,Guanylate_cyc,HNOBA,PAS_9
SRR25158347_k127_2681532_0	237368.SCABRO_03846	1.19e-28	123.0	COG3009@1|root,COG3009@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
SRR25158347_k127_2681532_1	641491.DND132_3438	1.559e-06	53.0	COG1463@1|root,COG1463@2|Bacteria,1MYEF@1224|Proteobacteria,42SPY@68525|delta/epsilon subdivisions,2WP3D@28221|Deltaproteobacteria,2MG7C@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related	-	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158347_k127_2683186_0	1121335.Clst_0559	1.48e-70	243.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
SRR25158347_k127_268389_1	572480.Arnit_2927	4.074e-134	430.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2YNIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NAD dependent epimerase dehydratase family	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158347_k127_268389_2	573370.DMR_p1_00280	9.729e-41	155.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
SRR25158347_k127_268389_0	331113.SNE_A16690	5.413e-151	490.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158347_k127_268561_0	1209989.TepiRe1_1360	1.965e-59	224.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia,42FWQ@68295|Thermoanaerobacterales	186801|Clostridia	L	COGs COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
SRR25158347_k127_2686384_0	391615.ABSJ01000054_gene1429	3.853e-131	424.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1J4PA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEcE24377_1341.EcE24377A_1004,iPC815.YPO1389,iYL1228.KPN_00935	Aminotran_5
SRR25158347_k127_2692890_0	1123070.KB899271_gene2350	1.959e-27	126.0	COG0265@1|root,COG0265@2|Bacteria,46SZ1@74201|Verrucomicrobia,2ITZC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
SRR25158347_k127_269323_0	102125.Xen7305DRAFT_00024870	0.0001813	54.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1GAZT@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_269326_1	509635.N824_03040	0.0009174	44.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1INMM@117747|Sphingobacteriia	976|Bacteroidetes	S	iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
SRR25158347_k127_269326_0	1121405.dsmv_0371	1.516e-63	228.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2MJPN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158347_k127_2696576_1	411474.COPEUT_00316	3.564e-14	78.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_2696576_0	1297863.APJF01000016_gene4345	1.166e-74	262.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,3JRI0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	MA20_25320	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_2699676_0	682795.AciX8_0555	1.586e-155	501.0	COG0044@1|root,COG0044@2|Bacteria,3Y34R@57723|Acidobacteria,2JIA3@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158347_k127_270121_2	865937.Gilli_1629	5.938e-14	78.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1HXBV@117743|Flavobacteriia,2P6A8@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158347_k127_270121_0	472759.Nhal_2864	1.214e-90	308.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1WWUF@135613|Chromatiales	135613|Chromatiales	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158347_k127_270121_1	765420.OSCT_0603	9.949e-31	132.0	COG2267@1|root,COG2267@2|Bacteria,2GB91@200795|Chloroflexi,377KC@32061|Chloroflexia	32061|Chloroflexia	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_270121_3	326427.Cagg_1657	9.38e-07	57.0	2A1DK@1|root,30PKS@2|Bacteria,2GANW@200795|Chloroflexi,376W4@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2708279_1	329726.AM1_5270	1.254e-09	68.0	2CRK8@1|root,32SP8@2|Bacteria,1G8H5@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
SRR25158347_k127_2708279_0	545695.TREAZ_1240	5.323e-10	71.0	COG1538@1|root,COG1538@2|Bacteria,2J8W8@203691|Spirochaetes	203691|Spirochaetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158347_k127_2708564_0	373994.Riv7116_5460	9.195e-87	300.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1G3JV@1117|Cyanobacteria,1HM4Z@1161|Nostocales	1117|Cyanobacteria	KLT	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CHAT,Pentapeptide,Peptidase_C14,TPR_8
SRR25158347_k127_2713064_0	56110.Oscil6304_5443	3.907e-85	299.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Hpt,Pkinase,Response_reg
SRR25158347_k127_2713064_2	1123276.KB893252_gene3723	9.429e-07	53.0	2EVNI@1|root,33P2K@2|Bacteria,4NYEM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2713064_1	504472.Slin_1012	4.623e-18	86.0	COG2886@1|root,COG2886@2|Bacteria,4NYD2@976|Bacteroidetes,47S8E@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
SRR25158347_k127_2714861_0	1279017.AQYJ01000028_gene2042	5.831e-13	69.0	COG3108@1|root,COG3108@2|Bacteria,1NDQH@1224|Proteobacteria,1T130@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRR25158347_k127_2714861_1	1449050.JNLE01000005_gene4675	2.123e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24HT2@186801|Clostridia,36M1C@31979|Clostridiaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158347_k127_2715141_0	1499967.BAYZ01000009_gene5377	2.72e-40	155.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,2NR1F@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HD_5,HisKA,PAS_4,Response_reg
SRR25158347_k127_2715141_1	1121904.ARBP01000005_gene4661	6.302e-06	56.0	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF4384,PG_binding_1
SRR25158347_k127_2717179_0	264462.Bd3281	2.033e-74	268.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,42NJV@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	COG2211 Na melibiose symporter and related	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158347_k127_2717179_1	694431.DESACE_08270	1.661e-05	47.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2M6UY@213113|Desulfurellales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158347_k127_2723523_0	204669.Acid345_4447	1.51e-13	82.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRR25158347_k127_2724373_3	272558.10174577	1.675e-07	57.0	arCOG10953@1|root,312TK@2|Bacteria,1VZXZ@1239|Firmicutes,4HYIM@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2724373_0	448385.sce5328	9.602e-275	857.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2YWT1@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
SRR25158347_k127_2724373_1	946483.Cenrod_0604	9.638e-18	98.0	COG0515@1|root,COG2340@1|root,COG3227@1|root,COG3637@1|root,COG4733@1|root,COG0515@2|Bacteria,COG2340@2|Bacteria,COG3227@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,1N79H@1224|Proteobacteria	1224|Proteobacteria	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
SRR25158347_k127_2724373_2	631362.Thi970DRAFT_01374	1.233e-09	71.0	COG0515@1|root,COG0515@2|Bacteria,1N79H@1224|Proteobacteria,1S6V2@1236|Gammaproteobacteria,1WZK3@135613|Chromatiales	135613|Chromatiales	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
SRR25158347_k127_2728225_0	1303518.CCALI_00290	1.094e-30	128.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158347_k127_273092_0	404589.Anae109_2071	9.2e-28	132.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_273092_1	13249.RPRC013400-PA	2.602e-13	79.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3BESA@33208|Metazoa,3CWK8@33213|Bilateria,41XC0@6656|Arthropoda,3SFQN@50557|Insecta	33208|Metazoa	T	cAMP-dependent protein kinase regulator activity. It is involved in the biological process described with regulation of protein phosphorylation	PRKAR2B	GO:0000086,GO:0000166,GO:0000278,GO:0000902,GO:0000904,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006082,GO:0006469,GO:0006629,GO:0006631,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007399,GO:0007409,GO:0007411,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007622,GO:0007623,GO:0007626,GO:0008150,GO:0008152,GO:0008603,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010389,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019752,GO:0019866,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022402,GO:0022406,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030104,GO:0030154,GO:0030182,GO:0030234,GO:0030291,GO:0030315,GO:0030425,GO:0030534,GO:0030551,GO:0030552,GO:0030554,GO:0031090,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0031966,GO:0031967,GO:0031975,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032870,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0036477,GO:0040011,GO:0042060,GO:0042220,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043025,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043197,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043279,GO:0043434,GO:0043436,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044297,GO:0044309,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0044853,GO:0045121,GO:0045202,GO:0045471,GO:0045475,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046677,GO:0046983,GO:0048148,GO:0048149,GO:0048468,GO:0048471,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051640,GO:0051641,GO:0051716,GO:0051726,GO:0060255,GO:0060271,GO:0060281,GO:0060282,GO:0060284,GO:0060359,GO:0061564,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072347,GO:0080090,GO:0090068,GO:0097159,GO:0097305,GO:0097332,GO:0097338,GO:0097367,GO:0097447,GO:0097458,GO:0097485,GO:0097546,GO:0097711,GO:0098589,GO:0098590,GO:0098772,GO:0098794,GO:0098805,GO:0098857,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0140056,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901990,GO:1902494,GO:1902749,GO:1902911,GO:1903047,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SRR25158347_k127_2733595_0	56110.Oscil6304_3107	3.737e-70	256.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GC6Z@1117|Cyanobacteria,1H6Y9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_2733798_1	525318.HMPREF0497_2796	1.329e-10	64.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3FC91@33958|Lactobacillaceae	91061|Bacilli	K	response regulator	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_2733798_0	1071073.KI530537_gene2561	1.309e-21	105.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,4IPV1@91061|Bacilli,1ZRF6@1386|Bacillus	91061|Bacilli	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
SRR25158347_k127_2734002_0	715226.ABI_08490	4.976e-47	182.0	COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria,2U8GE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158347_k127_273550_1	235279.HH_1501	2.172e-08	59.0	2E7TI@1|root,3328N@2|Bacteria,1NCCK@1224|Proteobacteria,4319D@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
SRR25158347_k127_273550_0	765420.OSCT_2074	1.9e-23	103.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi,376KE@32061|Chloroflexia	32061|Chloroflexia	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158347_k127_273690_1	1168034.FH5T_20820	1.777e-08	62.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2FRUD@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_273690_0	1168034.FH5T_20840	6.256e-71	254.0	COG3437@1|root,COG3437@2|Bacteria,4PMUU@976|Bacteroidetes,2G0H5@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_273690_2	889378.Spiaf_2232	5.527e-08	57.0	291RI@1|root,2ZPBI@2|Bacteria,2J8IP@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2740759_1	1249627.D779_4125	0.0001071	44.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_2740759_0	1279009.ADICEAN_04015	3.395e-38	163.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia	976|Bacteroidetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_2742717_0	161934.XP_010686771.1	1.855e-57	213.0	COG0464@1|root,KOG0730@2759|Eukaryota,37HTP@33090|Viridiplantae,3GH6T@35493|Streptophyta	35493|Streptophyta	O	Belongs to the AAA ATPase family	-	-	-	ko:K14012	ko04141,map04141	-	-	-	ko00000,ko00001	-	-	-	AAA
SRR25158347_k127_2759267_0	289376.THEYE_A0857	2.007e-38	151.0	COG0621@1|root,COG0621@2|Bacteria,3J0CD@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158347_k127_2759267_1	696281.Desru_1928	1.258e-07	59.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158347_k127_2764851_0	1449976.KALB_5976	6.208e-182	598.0	COG0110@1|root,COG0663@1|root,COG1020@1|root,COG0110@2|Bacteria,COG0663@2|Bacteria,COG1020@2|Bacteria,2I8TI@201174|Actinobacteria,4DZ27@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
SRR25158347_k127_2768746_0	945713.IALB_2428	3.798e-07	63.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158347_k127_2770322_0	796940.HMPREF9628_01768	5.155e-38	153.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,25SH1@186804|Peptostreptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158347_k127_2770322_1	643867.Ftrac_1492	1.335e-32	138.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158347_k127_2771573_2	243275.TDE_1505	1.237e-10	68.0	COG1585@1|root,COG1585@2|Bacteria,2J89B@203691|Spirochaetes	203691|Spirochaetes	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158347_k127_2771573_0	382464.ABSI01000011_gene3132	4.023e-97	326.0	COG0330@1|root,COG0330@2|Bacteria,46X93@74201|Verrucomicrobia,2IV2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal region of band_7	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
SRR25158347_k127_2771573_1	439235.Dalk_3750	8.868e-62	218.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria,2MHN9@213118|Desulfobacterales	28221|Deltaproteobacteria	O	C-terminal region of band_7	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
SRR25158347_k127_2774830_1	118168.MC7420_5347	8.283e-35	135.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
SRR25158347_k127_2774830_0	1188252.AJYK01000072_gene2107	3.013e-53	201.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XSNR@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
SRR25158347_k127_2782794_0	443143.GM18_4515	2.559e-76	263.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158347_k127_2782794_1	318161.Sden_0994	9.56e-73	254.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,2Q8S1@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E0035	DapB_C,DapB_N
SRR25158347_k127_2782794_2	1307761.L21SP2_2416	1.678e-43	169.0	COG1624@1|root,COG1624@2|Bacteria,2J5ZB@203691|Spirochaetes	203691|Spirochaetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158347_k127_2782794_3	742743.HMPREF9453_00178	1.348e-06	59.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4H55U@909932|Negativicutes	909932|Negativicutes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158347_k127_278445_0	1519464.HY22_09655	1.372e-35	138.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
SRR25158347_k127_2791329_0	1429916.X566_03340	1.973e-15	86.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,3JTYN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Function of homologous gene experimentally demonstrated in an other organism	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_2791329_1	608506.COB47_2013	1.875e-08	61.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,42F87@68295|Thermoanaerobacterales	186801|Clostridia	NT	SMART CheW domain protein	cheW1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158347_k127_2792436_0	404589.Anae109_1315	1.774e-94	319.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2YU37@29|Myxococcales	28221|Deltaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
SRR25158347_k127_2792436_2	944481.JAFP01000001_gene506	1.284e-46	174.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2M6ZG@213113|Desulfurellales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158347_k127_2792436_3	1123368.AUIS01000001_gene1952	2.018e-41	158.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,2ND0G@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
SRR25158347_k127_2792436_4	547144.HydHO_1483	5.574e-29	124.0	COG0235@1|root,COG0235@2|Bacteria,2G572@200783|Aquificae	200783|Aquificae	E	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158347_k127_2792436_1	1129794.C427_1408	1.218e-72	252.0	COG1028@1|root,COG3832@1|root,COG1028@2|Bacteria,COG3832@2|Bacteria,1P9R4@1224|Proteobacteria,1RYF6@1236|Gammaproteobacteria,469S0@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2,adh_short
SRR25158347_k127_279251_0	1123288.SOV_3c03850	1.083e-33	149.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158347_k127_279625_0	880073.Calab_1547	1.291e-144	466.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ,iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158347_k127_2796871_0	998088.B565_3178	2.726e-75	269.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y50Y@135624|Aeromonadales	135624|Aeromonadales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
SRR25158347_k127_2797078_1	1123288.SOV_3c05750	8.654e-09	67.0	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,4H4YE@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,PAS_9
SRR25158347_k127_2797078_0	765911.Thivi_2100	3.036e-18	96.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X0EM@135613|Chromatiales	135613|Chromatiales	NT	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
SRR25158347_k127_2799137_3	1116472.MGMO_45c00360	1.011e-08	56.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1XFG7@135618|Methylococcales	135618|Methylococcales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158347_k127_2799137_0	526224.Bmur_0635	2.077e-200	646.0	COG1185@1|root,COG1185@2|Bacteria,2J5BU@203691|Spirochaetes	203691|Spirochaetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158347_k127_2799137_1	1121428.DESHY_80080___1	2.555e-94	324.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158347_k127_2799137_2	177439.DP2607	3.606e-36	141.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,2MK9P@213118|Desulfobacterales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158347_k127_2803802_0	1122216.AUHW01000009_gene1690	7.964e-91	307.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H1Z4@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158347_k127_2803802_1	889378.Spiaf_1939	9.121e-26	110.0	COG1664@1|root,COG1664@2|Bacteria,2J85N@203691|Spirochaetes	203691|Spirochaetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158347_k127_2803802_2	1480694.DC28_03070	2.347e-15	76.0	COG2114@1|root,COG2114@2|Bacteria,2JAV7@203691|Spirochaetes	203691|Spirochaetes	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2805574_1	1201290.M902_1219	1.038e-29	124.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2MT2F@213481|Bdellovibrionales,2WN3M@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158347_k127_2805574_3	1123242.JH636436_gene420	5.921e-23	101.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158347_k127_2805574_0	485913.Krac_8822	2.035e-143	466.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158347_k127_2805574_2	1268635.Loa_02279	2.194e-28	119.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1JECN@118969|Legionellales	118969|Legionellales	C	NifU-like N terminal domain	nifU_1	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158347_k127_2805574_4	525904.Tter_1833	3.54e-21	97.0	COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria	2|Bacteria	S	Pfam:DUF59	yitW	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158347_k127_2813579_1	1131269.AQVV01000003_gene705	4.277e-165	524.0	COG0499@1|root,COG0499@2|Bacteria	2|Bacteria	H	adenosylhomocysteinase activity	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158347_k127_2813579_2	953739.SVEN_7039	9.496e-30	120.0	COG1146@1|root,COG1146@2|Bacteria,2GQEJ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
SRR25158347_k127_2813579_0	929556.Solca_3209	4.197e-319	993.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158347_k127_281493_1	1150600.ADIARSV_2874	6.178e-17	85.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158347_k127_281493_0	113355.CM001775_gene3036	2.486e-83	283.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
SRR25158347_k127_2815590_0	1121091.AUMP01000017_gene833	2.663e-22	101.0	COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes	1239|Firmicutes	T	universal stress protein	yxiE	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158347_k127_2815590_1	1392489.JPOL01000002_gene2581	9.943e-11	68.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1HXBP@117743|Flavobacteriia,2XIYT@283735|Leeuwenhoekiella	976|Bacteroidetes	G	Phosphomannose isomerase type I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SRR25158347_k127_281562_1	880072.Desac_2907	4.556e-31	127.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria,2MRBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
SRR25158347_k127_281562_3	1121104.AQXH01000001_gene1682	9.58e-08	58.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_281562_0	1337936.IJ00_18020	2.472e-31	126.0	COG4634@1|root,COG4634@2|Bacteria,1G6P5@1117|Cyanobacteria,1HNV5@1161|Nostocales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_281562_2	1535422.ND16A_1273	1.459e-22	99.0	COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,1S6HC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1226 Kef-type K transport systems	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158347_k127_2819559_2	500633.CLOHIR_01461	4.401e-06	59.0	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24REC@186801|Clostridia,25U0V@186804|Peptostreptococcaceae	186801|Clostridia	S	LysM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158347_k127_2819559_1	1125700.HMPREF9195_01937	9.198e-27	112.0	COG1366@1|root,COG1366@2|Bacteria,2J7R1@203691|Spirochaetes	203691|Spirochaetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_2819559_0	1322246.BN4_10209	8.88e-46	169.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2M9GZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158347_k127_2821355_0	941449.dsx2_0612	1.216e-07	66.0	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria,1MXJQ@1224|Proteobacteria,42RQT@68525|delta/epsilon subdivisions,2WPRU@28221|Deltaproteobacteria,2MAM5@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
SRR25158347_k127_2825243_2	572480.Arnit_1903	9.953e-05	48.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2YMMN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_2825243_0	1485545.JQLW01000008_gene1942	1.161e-74	271.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_2825243_1	5679.XP_010699960.1	6.342e-09	57.0	COG4642@1|root,COG5253@1|root,KOG1729@1|root,KOG0229@2759|Eukaryota,KOG0231@2759|Eukaryota,KOG1729@2759|Eukaryota,3XU6C@5653|Kinetoplastida	5653|Kinetoplastida	T	Protein present in Fab1, YOTB, Vac1, and EEA1	-	-	-	-	-	-	-	-	-	-	-	-	FYVE,MORN
SRR25158347_k127_2825604_1	2325.TKV_c18040	1.717e-30	130.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158347_k127_2825604_0	1123508.JH636450_gene7188	1.017e-139	462.0	COG0415@1|root,COG0415@2|Bacteria,2IXWI@203682|Planctomycetes	203682|Planctomycetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
SRR25158347_k127_2825604_2	1125701.HMPREF1221_01863	6.882e-14	76.0	COG1366@1|root,COG1366@2|Bacteria,2J7R1@203691|Spirochaetes	203691|Spirochaetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_2828857_0	264462.Bd0065	2.668e-76	263.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2MSUT@213481|Bdellovibrionales,2WIQN@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158347_k127_2829274_1	1121373.KB903625_gene3216	1.979e-06	49.0	COG2827@1|root,COG2827@2|Bacteria,4NW73@976|Bacteroidetes	976|Bacteroidetes	L	Excinuclease ABC	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158347_k127_2829274_0	1237149.C900_05403	2.528e-80	279.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158347_k127_283073_0	313606.M23134_05466	1.667e-88	306.0	COG2208@1|root,COG2905@1|root,COG2208@2|Bacteria,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	srrB	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,cNMP_binding,dCache_1
SRR25158347_k127_283285_0	1288494.EBAPG3_11750	4.976e-38	160.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE,KAP_NTPase,PG_binding_1,WD40
SRR25158347_k127_2835980_2	445970.ALIPUT_02152	2.808e-22	104.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia,22UPU@171550|Rikenellaceae	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158347_k127_2835980_1	526224.Bmur_0770	5.008e-34	138.0	COG0193@1|root,COG0193@2|Bacteria,2J8P8@203691|Spirochaetes	203691|Spirochaetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	ABM,Pept_tRNA_hydro
SRR25158347_k127_2835980_0	1009370.ALO_07018	3.629e-108	360.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4H2PQ@909932|Negativicutes	909932|Negativicutes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158347_k127_2837192_0	272123.Anacy_1154	3.8e-67	247.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4585@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4585@2|Bacteria,1GQ9E@1117|Cyanobacteria,1HIP0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA_3,PAS_4,Pkinase
SRR25158347_k127_2842545_1	1278073.MYSTI_04469	1.443e-08	63.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2842545_2	862514.HMPREF0623_0491	0.0003352	48.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3F3SS@33958|Lactobacillaceae	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
SRR25158347_k127_2842545_0	121225.PHUM529420-PA	4.015e-10	70.0	COG4886@1|root,KOG4641@2759|Eukaryota,39Z7Y@33154|Opisthokonta,3BKD5@33208|Metazoa,3CWKH@33213|Bilateria,41VSD@6656|Arthropoda,3SGRE@50557|Insecta,3E7YZ@33342|Paraneoptera	33208|Metazoa	T	Leucine rich repeat N-terminal domain	Tl	GO:0000578,GO:0002164,GO:0002225,GO:0002229,GO:0002239,GO:0002376,GO:0002520,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002788,GO:0002803,GO:0002804,GO:0002805,GO:0002807,GO:0002808,GO:0002810,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005121,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0006355,GO:0006357,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006963,GO:0006967,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007352,GO:0007389,GO:0007399,GO:0007416,GO:0007507,GO:0007525,GO:0007526,GO:0008037,GO:0008038,GO:0008039,GO:0008063,GO:0008150,GO:0008283,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009790,GO:0009791,GO:0009798,GO:0009880,GO:0009889,GO:0009891,GO:0009893,GO:0009897,GO:0009950,GO:0009953,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0012505,GO:0015026,GO:0016020,GO:0016043,GO:0016201,GO:0019219,GO:0019222,GO:0019730,GO:0019732,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019955,GO:0022008,GO:0022607,GO:0023052,GO:0030097,GO:0030154,GO:0030182,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031410,GO:0031982,GO:0032101,GO:0032103,GO:0032153,GO:0032154,GO:0032155,GO:0032501,GO:0032502,GO:0032991,GO:0034248,GO:0034250,GO:0035007,GO:0035172,GO:0038023,GO:0040011,GO:0042221,GO:0042330,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043455,GO:0043900,GO:0043902,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045595,GO:0045610,GO:0045893,GO:0045935,GO:0045944,GO:0045995,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048569,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050808,GO:0050830,GO:0050832,GO:0050896,GO:0050919,GO:0051171,GO:0051173,GO:0051239,GO:0051252,GO:0051254,GO:0051704,GO:0051707,GO:0051716,GO:0060089,GO:0060255,GO:0061061,GO:0065007,GO:0070976,GO:0071840,GO:0071944,GO:0072359,GO:0080090,GO:0080134,GO:0097708,GO:0098542,GO:0098552,GO:0098590,GO:1900150,GO:1900424,GO:1900426,GO:1902680,GO:1902875,GO:1903506,GO:1903508,GO:2000026,GO:2000112,GO:2001141	-	ko:K18809	ko04624,map04624	M00686	-	-	ko00000,ko00001,ko00002	-	-	-	LRRNT,LRR_5,LRR_8,TIR
SRR25158347_k127_2848055_2	1144319.PMI16_04700	3.688e-31	124.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2VU66@28216|Betaproteobacteria,4789E@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158347_k127_2848055_0	1121033.AUCF01000009_gene1174	5.747e-108	355.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2JSGM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158347_k127_2848055_1	113395.AXAI01000011_gene6425	7.295e-40	149.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,3JXG2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158347_k127_2849428_0	1265313.HRUBRA_00217	3.064e-97	326.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1J5HD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
SRR25158347_k127_2849428_1	1042376.AFPK01000028_gene2016	4.552e-80	274.0	COG3769@1|root,COG3769@2|Bacteria,4P1MD@976|Bacteroidetes	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158347_k127_2849428_2	1165841.SULAR_03702	1.021e-64	227.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM MOFRL domain protein	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158347_k127_2849664_2	641526.ADIWIN_3798	0.00054	51.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
SRR25158347_k127_2849664_1	1313421.JHBV01000022_gene4745	1.844e-31	134.0	28HRJ@1|root,2Z7YZ@2|Bacteria,4NHRE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2849664_0	1122138.AQUZ01000005_gene2699	2.73e-44	164.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,4DPAH@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2850199_0	572479.Hprae_0966	3.461e-27	123.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia,3WAEQ@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM DnaQ family exonuclease DinG family helicase	dinG	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T,RadC,ResIII
SRR25158347_k127_2852378_1	179408.Osc7112_1906	1.52e-11	66.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1G26V@1117|Cyanobacteria,1H78U@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_2852378_0	402777.KB235904_gene3290	1.48e-67	249.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1G2HD@1117|Cyanobacteria,1H728@1150|Oscillatoriales	1117|Cyanobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,MCPsignal
SRR25158347_k127_2853161_0	83406.HDN1F_00640	3.315e-98	329.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1J529@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_2857146_1	313606.M23134_04579	6.1e-109	361.0	COG2227@1|root,COG2227@2|Bacteria,4NNQC@976|Bacteroidetes,47U7K@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158347_k127_2857146_0	2340.JV46_19230	2.356e-153	494.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_2858415_0	580340.Tlie_0581	5.056e-38	154.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,3T9T4@508458|Synergistetes	508458|Synergistetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SRR25158347_k127_2860291_0	329726.AM1_3854	1.95e-89	302.0	COG0566@1|root,COG0566@2|Bacteria,1G5MN@1117|Cyanobacteria	1117|Cyanobacteria	J	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158347_k127_2864458_0	1184267.A11Q_297	5.044e-09	61.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158347_k127_2871533_1	1111134.HMPREF1253_0952	8.422e-18	89.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,22GTG@1570339|Peptoniphilaceae	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
SRR25158347_k127_2871533_0	795359.TOPB45_0425	3.921e-88	298.0	COG0014@1|root,COG0014@2|Bacteria,2GH1U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158347_k127_287180_1	1123277.KB893195_gene5599	2.465e-41	154.0	COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,47MQ2@768503|Cytophagia	976|Bacteroidetes	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
SRR25158347_k127_287180_0	1316936.K678_13413	2.649e-100	334.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,2JPC4@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158347_k127_2874270_0	489825.LYNGBM3L_74940	6.499e-57	205.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158347_k127_2874270_1	1392498.JQLH01000001_gene105	4.027e-22	104.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,1HWM9@117743|Flavobacteriia,2PHV4@252356|Maribacter	976|Bacteroidetes	T	Type IV pili methyl-accepting chemotaxis transducer N-term	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
SRR25158347_k127_2874414_3	476272.RUMHYD_00976	0.0001622	48.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158347_k127_2874414_0	5786.XP_003286359.1	1.375e-16	89.0	COG0170@1|root,KOG4453@2759|Eukaryota,3XDDN@554915|Amoebozoa	554915|Amoebozoa	I	phytol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2874414_1	118168.MC7420_1061	1.62e-14	80.0	COG5350@1|root,COG5350@2|Bacteria,1G4AH@1117|Cyanobacteria,1HH46@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	DSPc,HEAT_2,HEAT_PBS
SRR25158347_k127_2874414_2	400682.PAC_15703209	1.182e-06	55.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15503,ko:K16726,ko:K21440	-	-	-	-	ko00000,ko01009,ko03036,ko03400,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158347_k127_287462_0	886293.Sinac_4649	2.377e-65	239.0	2BKPT@1|root,32F5G@2|Bacteria,2J1GG@203682|Planctomycetes	203682|Planctomycetes	S	PcfJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfJ
SRR25158347_k127_287462_1	317936.Nos7107_3423	1.181e-25	111.0	COG0666@1|root,COG0666@2|Bacteria,1G52C@1117|Cyanobacteria,1HNY7@1161|Nostocales	1117|Cyanobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SRR25158347_k127_2875357_0	1123234.AUKI01000015_gene2324	3.591e-136	440.0	COG0438@1|root,COG0438@2|Bacteria,4NICT@976|Bacteroidetes,1HZ2P@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
SRR25158347_k127_2876001_0	1279009.ADICEAN_02849	1.518e-58	209.0	COG3264@1|root,COG3264@2|Bacteria,4NFMR@976|Bacteroidetes,47KC1@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
SRR25158347_k127_2876001_1	1173025.GEI7407_3779	1.026e-26	118.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1HFHP@1150|Oscillatoriales	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158347_k127_2876001_3	1177179.A11A3_11458	4.489e-07	54.0	2E7TI@1|root,333ZE@2|Bacteria,1NA5N@1224|Proteobacteria,1SE9F@1236|Gammaproteobacteria,1XQVH@135619|Oceanospirillales	135619|Oceanospirillales	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
SRR25158347_k127_2876049_0	665571.STHERM_c22280	2.497e-20	102.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2J5K8@203691|Spirochaetes	203691|Spirochaetes	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
SRR25158347_k127_2879535_1	1430440.MGMSRv2_3803	8.695e-08	57.0	2DNKW@1|root,32Y18@2|Bacteria,1ND1M@1224|Proteobacteria,2UNZP@28211|Alphaproteobacteria,2JW16@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2879535_0	103690.17133360	1.582e-25	115.0	COG5001@1|root,COG5001@2|Bacteria,1G2MB@1117|Cyanobacteria,1HKX4@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158347_k127_2881566_1	909663.KI867150_gene1456	7.411e-11	66.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2MQV7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_2881566_0	273068.TTE1713	3.717e-123	405.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,42EQA@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158347_k127_2882072_0	153721.MYP_983	1.071e-84	301.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158347_k127_2884035_0	1121094.KB894643_gene1732	1.066e-27	116.0	COG1974@1|root,COG1974@2|Bacteria,4PPIB@976|Bacteroidetes,2G160@200643|Bacteroidia	976|Bacteroidetes	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158347_k127_2886352_4	1283287.KB822578_gene2556	4.723e-13	81.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158347_k127_2886352_2	1184267.A11Q_1080	1.025e-36	144.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2MUST@213481|Bdellovibrionales,2WPPE@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_2886352_1	96561.Dole_2412	2.558e-54	199.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
SRR25158347_k127_2886352_0	394503.Ccel_0969	7.512e-139	449.0	COG1088@1|root,COG1088@2|Bacteria,1VW04@1239|Firmicutes	1239|Firmicutes	M	Polysaccharide biosynthesis protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158347_k127_2886352_3	1042376.AFPK01000029_gene1497	2.287e-13	82.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,1HX0G@117743|Flavobacteriia,406TG@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_2886352_5	797209.ZOD2009_21252	1.75e-07	63.0	COG1208@1|root,arCOG00664@2157|Archaea,2XTG9@28890|Euryarchaeota,23T96@183963|Halobacteria	183963|Halobacteria	M	COG1209 dTDP-glucose pyrophosphorylase	aglF	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158347_k127_2886879_0	562970.Btus_2131	7.146e-30	123.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,4ITQM@91061|Bacilli	91061|Bacilli	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SRR25158347_k127_2887958_1	313624.NSP_40490	1.93e-28	116.0	COG2954@1|root,COG2954@2|Bacteria,1G5NQ@1117|Cyanobacteria,1HN42@1161|Nostocales	1117|Cyanobacteria	S	CYTH	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
SRR25158347_k127_2887958_0	1048983.EL17_21455	1.546e-248	770.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,47KGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRR25158347_k127_2890387_0	869209.Tresu_1582	9.695e-73	256.0	COG1198@1|root,COG1198@2|Bacteria,2J5B4@203691|Spirochaetes	203691|Spirochaetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158347_k127_2890387_1	237368.SCABRO_03759	1.175e-34	137.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
SRR25158347_k127_2890676_1	402612.FP1085	4.132e-11	74.0	COG0061@1|root,COG0061@2|Bacteria,4NG3P@976|Bacteroidetes,1HZV7@117743|Flavobacteriia	976|Bacteroidetes	G	ATP-NAD kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
SRR25158347_k127_2890676_0	1308866.J416_07427	8e-57	204.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,46ZP0@74385|Gracilibacillus	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158347_k127_2891464_0	945713.IALB_3141	3.996e-22	103.0	COG3258@1|root,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3,DUF3365
SRR25158347_k127_2891809_1	1502851.FG93_00264	1.357e-18	87.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,3JSMU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	MA20_42330	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158347_k127_2891809_0	883103.HMPREF9703_00018	5.833e-37	151.0	COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,27GBY@186828|Carnobacteriaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158347_k127_289244_1	411154.GFO_0580	1.719e-64	224.0	COG0438@1|root,COG0438@2|Bacteria,4NE53@976|Bacteroidetes,1HX83@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158347_k127_289244_0	411154.GFO_0579	3.027e-92	306.0	COG0500@1|root,COG0500@2|Bacteria,4NHEV@976|Bacteroidetes,1I055@117743|Flavobacteriia	976|Bacteroidetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158347_k127_2893095_0	517418.Ctha_0898	5.244e-89	303.0	COG0477@1|root,COG0477@2|Bacteria,1FE42@1090|Chlorobi	1090|Chlorobi	P	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRR25158347_k127_2893095_1	383372.Rcas_2765	1.426e-06	51.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi,375YQ@32061|Chloroflexia	32061|Chloroflexia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158347_k127_2893458_0	927658.AJUM01000042_gene1675	1.775e-251	783.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,2FNGK@200643|Bacteroidia,3XJY6@558415|Marinilabiliaceae	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
SRR25158347_k127_2893458_1	682795.AciX8_0028	1.32e-62	217.0	COG0863@1|root,COG0863@2|Bacteria,3Y5XP@57723|Acidobacteria,2JNNJ@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158347_k127_2896578_0	1289135.A966_06555	5.638e-11	73.0	COG0535@1|root,COG0535@2|Bacteria,2J6HP@203691|Spirochaetes	203691|Spirochaetes	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158347_k127_2896578_1	316067.Geob_3713	1.669e-08	66.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,43TFD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
SRR25158347_k127_2899975_1	272123.Anacy_5295	0.0006493	51.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1GQ9E@1117|Cyanobacteria,1HIP0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_2899975_0	398512.JQKC01000067_gene4262	1.739e-05	51.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1UK1R@1239|Firmicutes,25FHG@186801|Clostridia	186801|Clostridia	KLT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase
SRR25158347_k127_290399_1	935845.JADQ01000003_gene990	7.028e-128	420.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,26SR3@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
SRR25158347_k127_290399_2	313612.L8106_04936	1.221e-97	326.0	COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,1G38Q@1117|Cyanobacteria,1HACP@1150|Oscillatoriales	1117|Cyanobacteria	H	Mycolic acid cyclopropane synthetase	sdmt	GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052729,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.1.1.157,2.1.1.161	ko:K13042,ko:K18897	ko00260,map00260	-	R07244,R10061	RC00003,RC00496,RC03040	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11
SRR25158347_k127_290399_0	313612.L8106_04936	4.58e-136	437.0	COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,1G38Q@1117|Cyanobacteria,1HACP@1150|Oscillatoriales	1117|Cyanobacteria	H	Mycolic acid cyclopropane synthetase	sdmt	GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052729,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.1.1.157,2.1.1.161	ko:K13042,ko:K18897	ko00260,map00260	-	R07244,R10061	RC00003,RC00496,RC03040	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11
SRR25158347_k127_2906244_0	452471.Aasi_0223	1.638e-63	228.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,47MPX@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158347_k127_290807_1	1121938.AUDY01000007_gene2501	8.57e-08	53.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_290807_0	469596.HMPREF9488_02666	9.18e-37	154.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,3VNR3@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158347_k127_2908797_2	996637.SGM_6715	4.726e-06	55.0	COG0331@1|root,COG0331@2|Bacteria,2ICPW@201174|Actinobacteria	201174|Actinobacteria	I	[acyl-carrier-protein] S-malonyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2908797_0	237368.SCABRO_01989	1.132e-78	282.0	COG2251@1|root,COG2251@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779,HHH_5,RNase_H_2
SRR25158347_k127_2908797_1	1353529.M899_1476	6.437e-78	269.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2MSRF@213481|Bdellovibrionales,2X6YW@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
SRR25158347_k127_2913455_0	321332.CYB_2140	3.572e-89	330.0	COG2373@1|root,COG2373@2|Bacteria,1G1A1@1117|Cyanobacteria,1H0M9@1129|Synechococcus	1117|Cyanobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,CarboxypepD_reg,MG1,Thiol-ester_cl
SRR25158347_k127_291396_0	1280692.AUJL01000031_gene1980	2.504e-87	298.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,36E39@31979|Clostridiaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158347_k127_2915893_0	1195236.CTER_1977	1.696e-98	339.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Cadherin-like,Flg_new,He_PIG,Peptidase_C69,Rhamnogal_lyase,SLH,fn3_3
SRR25158347_k127_2915926_0	522772.Dacet_2534	3.108e-52	190.0	COG0502@1|root,COG0502@2|Bacteria,2GEKH@200930|Deferribacteres	200930|Deferribacteres	C	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
SRR25158347_k127_2916533_0	314278.NB231_00530	1.934e-05	48.0	COG0500@1|root,COG0500@2|Bacteria,1R53Q@1224|Proteobacteria,1SMCT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2917969_0	1173029.JH980292_gene2348	8.118e-178	572.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
SRR25158347_k127_2925250_0	345219.Bcoa_1298	1.84e-62	216.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158347_k127_2925250_1	344747.PM8797T_09994	6.079e-12	70.0	COG4782@1|root,COG4782@2|Bacteria,2IWWR@203682|Planctomycetes	2|Bacteria	B	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
SRR25158347_k127_2925833_0	402777.KB235903_gene2646	5.172e-15	87.0	COG2114@1|root,COG2114@2|Bacteria,1GQRR@1117|Cyanobacteria,1H9GQ@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,PAS_4
SRR25158347_k127_2929740_0	1321778.HMPREF1982_04325	1.007e-84	295.0	COG5002@1|root,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia,26CJ9@186813|unclassified Clostridiales	186801|Clostridia	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,MASE3,PAS_8
SRR25158347_k127_2931609_0	1173029.JH980292_gene2754	3.22e-45	166.0	COG1216@1|root,COG1216@2|Bacteria,1G48C@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_293175_0	880073.Calab_3322	2.809e-100	342.0	COG0845@1|root,COG0845@2|Bacteria,2NP3Y@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
SRR25158347_k127_293175_1	1191523.MROS_0773	4.3e-47	170.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SRR25158347_k127_293490_2	650150.ERH_0635	6.107e-06	49.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,3VRA8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158347_k127_293490_0	1304284.L21TH_0979	3.022e-67	235.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,36EJ7@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158347_k127_293490_1	754027.HMPREF9554_01384	1.705e-18	88.0	COG0335@1|root,COG0335@2|Bacteria,2J825@203691|Spirochaetes	203691|Spirochaetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158347_k127_2936715_0	997346.HMPREF9374_1664	6.423e-55	199.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,27AV9@186824|Thermoactinomycetaceae	91061|Bacilli	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158347_k127_2936715_1	1397666.RS24_00793	3.748e-46	172.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U1NZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058,ko:K03778	ko00260,ko00620,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00620,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00704,R00717,R01388,R01513	RC00031,RC00042,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158347_k127_2936951_0	929703.KE386491_gene1837	4.052e-38	144.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158347_k127_2938601_0	1173028.ANKO01000017_gene82	7.913e-58	214.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_2938723_0	1123376.AUIU01000016_gene291	2.875e-131	433.0	COG0165@1|root,COG0165@2|Bacteria,3J0EN@40117|Nitrospirae	40117|Nitrospirae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158347_k127_2938838_2	1117318.PRUB_06715	1.506e-05	49.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,2Q1CH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158347_k127_2938838_0	706587.Desti_1570	9.425e-80	290.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,42ZSC@68525|delta/epsilon subdivisions,2WUTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158347_k127_2938838_1	706587.Desti_1566	4.191e-15	76.0	2DI1Z@1|root,301RV@2|Bacteria,1NM7Q@1224|Proteobacteria,433HJ@68525|delta/epsilon subdivisions,2WXZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158347_k127_293940_0	1461577.CCMH01000037_gene158	2.141e-90	303.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158347_k127_294423_0	1123274.KB899421_gene1771	1.252e-70	262.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2J5MW@203691|Spirochaetes	203691|Spirochaetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158347_k127_2944254_0	1396141.BATP01000040_gene2118	1.592e-168	543.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,2IU04@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Phosphoenolpyruvate carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	PEPcase
SRR25158347_k127_2946134_1	926692.AZYG01000069_gene1728	6.029e-18	94.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,3WBT0@53433|Halanaerobiales	186801|Clostridia	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_2946134_0	391603.FBALC1_05508	5.438e-19	91.0	COG3324@1|root,COG3324@2|Bacteria,4NSBC@976|Bacteroidetes,1I3WN@117743|Flavobacteriia	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158347_k127_294733_0	744872.Spica_1365	2.137e-34	139.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2J5MW@203691|Spirochaetes	203691|Spirochaetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158347_k127_294733_1	421531.IX38_03805	2.921e-20	94.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,1HZ4Y@117743|Flavobacteriia,3ZRNN@59732|Chryseobacterium	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158347_k127_2949038_0	2325.TKV_c11610	6.895e-123	407.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,42EUK@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158347_k127_2957439_0	1173029.JH980292_gene2348	1.447e-200	642.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
SRR25158347_k127_2958108_3	1168034.FH5T_21145	2.352e-37	144.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes	976|Bacteroidetes	H	Molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158347_k127_2958108_1	313603.FB2170_09381	3.13e-53	196.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia,2PGTI@252356|Maribacter	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158347_k127_2958108_0	153721.MYP_153	2.312e-102	342.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,47M7C@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
SRR25158347_k127_2958108_2	714943.Mucpa_5095	1.751e-38	152.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1IQAR@117747|Sphingobacteriia	976|Bacteroidetes	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158347_k127_2959975_1	1121889.AUDM01000021_gene537	7.3e-26	109.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia,2NSGS@237|Flavobacterium	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158347_k127_2959975_2	700598.Niako_3009	1.636e-25	111.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1ISRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158347_k127_2959975_0	313606.M23134_05892	1.704e-152	486.0	COG0714@1|root,COG0714@2|Bacteria,4P0WM@976|Bacteroidetes	976|Bacteroidetes	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158347_k127_2960716_1	313606.M23134_07021	1.942e-19	92.0	COG0061@1|root,COG0061@2|Bacteria,4NG3P@976|Bacteroidetes,47M9J@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
SRR25158347_k127_2960716_0	313606.M23134_07020	7.868e-82	278.0	COG0330@1|root,COG0330@2|Bacteria,4NHKT@976|Bacteroidetes,47Q4F@768503|Cytophagia	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_2962952_0	449447.MAE_33400	2.526e-41	172.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,PAS_9,Pkinase,Response_reg
SRR25158347_k127_2967344_4	583355.Caka_2913	3.893e-44	163.0	COG3005@1|root,COG3005@2|Bacteria,46T0N@74201|Verrucomicrobia,3K8D9@414999|Opitutae	414999|Opitutae	C	TIGRFAM cytochrome c nitrate reductase, small subunit	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
SRR25158347_k127_2967344_0	583355.Caka_2912	3.77e-231	722.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia,3K7Z3@414999|Opitutae	414999|Opitutae	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SRR25158347_k127_2967344_6	944435.AXAJ01000010_gene3253	1.189e-10	67.0	COG2105@1|root,COG2105@2|Bacteria,1NIAM@1224|Proteobacteria,2VVWY@28216|Betaproteobacteria,1K8TK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158347_k127_2967344_1	237368.SCABRO_00068	4.179e-85	294.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2IX0R@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR25158347_k127_2967344_5	448385.sce6801	5.686e-32	130.0	COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,4382F@68525|delta/epsilon subdivisions,2X9VM@28221|Deltaproteobacteria,2YVEQ@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
SRR25158347_k127_2967344_2	665571.STHERM_c21350	3.851e-80	271.0	COG0717@1|root,COG0717@2|Bacteria,2JAA9@203691|Spirochaetes	203691|Spirochaetes	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158347_k127_2967344_3	1385514.N782_17645	1.049e-70	247.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,2Y8VJ@289201|Pontibacillus	91061|Bacilli	I	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158347_k127_29698_0	269798.CHU_2373	1.916e-122	407.0	COG2453@1|root,COG2453@2|Bacteria,4NXZM@976|Bacteroidetes,47WA1@768503|Cytophagia	976|Bacteroidetes	T	Protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
SRR25158347_k127_2970668_1	1307761.L21SP2_0385	4.643e-31	124.0	COG3436@1|root,COG3436@2|Bacteria,2J92E@203691|Spirochaetes	203691|Spirochaetes	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
SRR25158347_k127_2970668_0	1304885.AUEY01000056_gene1443	1.242e-86	306.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,43CRI@68525|delta/epsilon subdivisions,2X7Z7@28221|Deltaproteobacteria,2MIWI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
SRR25158347_k127_2974078_0	1229203.KI301992_gene30	2.49e-17	91.0	COG2911@1|root,COG3391@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,2GK45@201174|Actinobacteria,3UXMH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Lactonase,TIG
SRR25158347_k127_2974078_1	889378.Spiaf_0473	8.336e-05	54.0	293BT@1|root,2ZQUE@2|Bacteria,2J5IN@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_2977161_0	1121346.KB899839_gene1163	8.693e-186	593.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26QCH@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158347_k127_2977161_1	1118055.CAGU01000006_gene1091	7.729e-05	48.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,22GV3@1570339|Peptoniphilaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158347_k127_2978281_0	1111732.AZOD01000026_gene662	1.61e-58	209.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1X4QH@135614|Xanthomonadales	135614|Xanthomonadales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158347_k127_2978281_1	1319815.HMPREF0202_00728	7.051e-42	164.0	COG0793@1|root,COG0793@2|Bacteria,3786X@32066|Fusobacteria	32066|Fusobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158347_k127_298666_0	1396858.Q666_07595	3.869e-25	112.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,1S4N1@1236|Gammaproteobacteria,46AZQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
SRR25158347_k127_2986902_0	443152.MDG893_07715	2.446e-112	374.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RZSX@1236|Gammaproteobacteria,46DGD@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_2986902_1	1089551.KE386572_gene3766	1.225e-05	51.0	COG3173@1|root,COG3173@2|Bacteria,1MY0Y@1224|Proteobacteria,2TRMW@28211|Alphaproteobacteria,4BR4N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	MA20_16375	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_2987711_0	759914.BP951000_1947	2.56e-27	115.0	COG1160@1|root,COG1160@2|Bacteria,2J5GG@203691|Spirochaetes	203691|Spirochaetes	I	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158347_k127_2987711_1	1123511.KB905844_gene1170	6.964e-25	111.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4H2BC@909932|Negativicutes	909932|Negativicutes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158347_k127_2987711_2	330214.NIDE0007	9.454e-07	51.0	COG0691@1|root,COG0691@2|Bacteria,3J0Q4@40117|Nitrospirae	40117|Nitrospirae	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158347_k127_2988290_0	264462.Bd0888	1.79e-98	333.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MSRN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158347_k127_2988290_1	1298593.TOL_2818	8.079e-27	128.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1SZT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_298848_1	1121912.AUHD01000004_gene2190	2.515e-05	51.0	COG2318@1|root,COG2318@2|Bacteria,4NUTN@976|Bacteroidetes,1I1SI@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158347_k127_298848_0	504472.Slin_0771	2.404e-39	155.0	COG3023@1|root,COG3023@2|Bacteria,4NMIV@976|Bacteroidetes,47PNG@768503|Cytophagia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
SRR25158347_k127_299631_0	203124.Tery_1252	1.4e-80	278.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria,1H7D3@1150|Oscillatoriales	1117|Cyanobacteria	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158347_k127_2996428_0	448385.sce2064	9.977e-55	200.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2YUPX@29|Myxococcales	28221|Deltaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_2996999_0	743722.Sph21_3368	4.966e-111	363.0	COG2308@1|root,COG2308@2|Bacteria,4NFMN@976|Bacteroidetes,1INRP@117747|Sphingobacteriia	976|Bacteroidetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158347_k127_2996999_1	583355.Caka_1257	7.93e-62	222.0	COG2307@1|root,COG2307@2|Bacteria,46S7Q@74201|Verrucomicrobia,3K7VZ@414999|Opitutae	414999|Opitutae	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRR25158347_k127_299883_1	1279009.ADICEAN_01648	2.99e-88	297.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,47MXN@768503|Cytophagia	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158347_k127_299883_3	1313301.AUGC01000012_gene1381	2.405e-36	139.0	COG3288@1|root,COG3288@2|Bacteria,4NT78@976|Bacteroidetes	976|Bacteroidetes	C	Pyridine nucleotide transhydrogenase	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158347_k127_299883_0	1279009.ADICEAN_01646	3.348e-169	538.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,47KX8@768503|Cytophagia	976|Bacteroidetes	C	Alanine dehydrogenase/PNT, C-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158347_k127_299883_2	1347392.CCEZ01000049_gene1389	2.833e-56	201.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,36IPD@31979|Clostridiaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
SRR25158347_k127_299891_0	1121930.AQXG01000002_gene1967	3.688e-23	102.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1IT0D@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
SRR25158347_k127_3002381_0	926561.KB900620_gene3146	3.07e-23	112.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WA96@53433|Halanaerobiales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158347_k127_3004112_0	221288.JH992901_gene1423	2.293e-161	525.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1G4QT@1117|Cyanobacteria,1JJWQ@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,Pkinase
SRR25158347_k127_3004112_2	1304885.AUEY01000003_gene534	4.471e-28	118.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,42TBQ@68525|delta/epsilon subdivisions,2WPWC@28221|Deltaproteobacteria,2MPSG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SRR25158347_k127_3004112_1	1123508.JH636441_gene3478	1.995e-49	188.0	COG2124@1|root,COG2124@2|Bacteria,2IZTH@203682|Planctomycetes	203682|Planctomycetes	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158347_k127_3009165_2	311424.DhcVS_1275	2.957e-23	106.0	COG4832@1|root,COG4832@2|Bacteria,2G9F2@200795|Chloroflexi,34CUG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR25158347_k127_3009165_1	439235.Dalk_3706	2.42e-67	242.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_3009165_0	580327.Tthe_1566	1.511e-106	354.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,42F5U@68295|Thermoanaerobacterales	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158347_k127_3010018_0	1125863.JAFN01000001_gene1028	2.088e-198	626.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2WKYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158347_k127_30114_0	1313421.JHBV01000041_gene3455	4.154e-142	458.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1IPEQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158347_k127_30114_1	926550.CLDAP_01120	9.073e-55	199.0	COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
SRR25158347_k127_3012490_0	340170.XP_007375511.1	3.987e-93	310.0	COG0492@1|root,KOG0404@2759|Eukaryota,38I0K@33154|Opisthokonta,3NW0C@4751|Fungi,3QKA3@4890|Ascomycota,3RTJG@4891|Saccharomycetes,47CDG@766764|Debaryomycetaceae	4751|Fungi	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	TRR1	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0009636,GO:0009987,GO:0010035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019430,GO:0019725,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.6.5.5,1.8.1.9	ko:K00344,ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_3014107_0	1304885.AUEY01000044_gene232	8.911e-116	398.0	COG0745@1|root,COG4191@1|root,COG5002@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,43BK1@68525|delta/epsilon subdivisions,2X6XW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
SRR25158347_k127_3014107_1	1122179.KB890440_gene1026	2.03e-83	283.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,1IVFH@117747|Sphingobacteriia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
SRR25158347_k127_301532_1	1094715.CM001373_gene2562	3.628e-75	268.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1JFYY@118969|Legionellales	118969|Legionellales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158347_k127_301532_0	1519464.HY22_06245	1.628e-164	534.0	COG2268@1|root,COG2268@2|Bacteria	2|Bacteria	T	Band 7 protein	yqiK	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SRR25158347_k127_301532_2	1121335.Clst_0823	3.284e-05	48.0	29F7N@1|root,3025B@2|Bacteria,1V7G9@1239|Firmicutes,24KI2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158347_k127_3015334_0	497964.CfE428DRAFT_2397	4.329e-81	276.0	COG1858@1|root,COG1858@2|Bacteria,46SJU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem cytochrome c peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR25158347_k127_3016147_0	518766.Rmar_0668	3.959e-31	129.0	COG1259@1|root,COG3880@1|root,COG1259@2|Bacteria,COG3880@2|Bacteria,4NGSW@976|Bacteroidetes,1FJBZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
SRR25158347_k127_3017545_0	1123325.JHUV01000010_gene1153	4.139e-103	345.0	COG0172@1|root,COG0172@2|Bacteria,2G3RF@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158347_k127_3017545_2	411465.PEPMIC_01688	6.341e-57	207.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,22G6R@1570339|Peptoniphilaceae	186801|Clostridia	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158347_k127_3017545_3	639282.DEFDS_0202	1.965e-26	121.0	COG0739@1|root,COG0739@2|Bacteria,2GF3Z@200930|Deferribacteres	200930|Deferribacteres	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_3017545_4	1047013.AQSP01000133_gene2159	3.687e-21	97.0	COG1664@1|root,COG1664@2|Bacteria,2NQ1N@2323|unclassified Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
SRR25158347_k127_3017545_5	1410661.JNKW01000013_gene2213	7.285e-05	51.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,24S6C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
SRR25158347_k127_3017545_1	1120977.JHUX01000003_gene673	6.321e-90	306.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,1T22N@1236|Gammaproteobacteria,3NR0V@468|Moraxellaceae	1236|Gammaproteobacteria	S	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158347_k127_3022562_0	862908.BMS_1254	1.915e-40	166.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,42QEW@68525|delta/epsilon subdivisions,2MUQH@213481|Bdellovibrionales,2WJQI@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158347_k127_3023687_0	550540.Fbal_1180	2.604e-56	200.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0000287,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006166,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042440,GO:0042451,GO:0042455,GO:0042802,GO:0043094,GO:0043096,GO:0043101,GO:0043167,GO:0043169,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046128,GO:0046129,GO:0046148,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C0496,ic_1306.c0588	Pribosyltran
SRR25158347_k127_3026980_0	1198232.CYCME_1971	1.192e-74	259.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,4603Z@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
SRR25158347_k127_3026980_1	384765.SIAM614_02396	1.639e-11	72.0	COG5381@1|root,COG5381@2|Bacteria,1N980@1224|Proteobacteria,2UI73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3028561_1	945713.IALB_0830	2.405e-07	55.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,SSF,SpoIIE
SRR25158347_k127_3028561_2	1480694.DC28_06775	5.494e-05	51.0	297PQ@1|root,2ZUWM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158347_k127_3031494_0	395964.KE386496_gene2561	2.886e-61	221.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TTJ5@28211|Alphaproteobacteria,3NBGD@45404|Beijerinckiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,adh_short
SRR25158347_k127_3031494_1	485918.Cpin_0754	3.423e-14	73.0	COG2425@1|root,COG2425@2|Bacteria,4NJR2@976|Bacteroidetes,1IQJJ@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
SRR25158347_k127_3031605_3	868131.MSWAN_0049	2.123e-05	56.0	COG3291@1|root,arCOG02516@1|root,arCOG07611@1|root,arCOG09475@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG07611@2157|Archaea,arCOG09475@2157|Archaea	2157|Archaea	E	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CARDB,CHB_HEX_C_1,DUF11,PKD,PQQ_3
SRR25158347_k127_3031605_1	349124.Hhal_0051	1.964e-28	119.0	2CHIC@1|root,2ZNB5@2|Bacteria,1RBRG@1224|Proteobacteria,1S2NN@1236|Gammaproteobacteria,1WY5X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2452)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2452
SRR25158347_k127_3031605_2	1122207.MUS1_11795	3.169e-12	76.0	COG5608@1|root,COG5608@2|Bacteria,1N4VR@1224|Proteobacteria,1SAT2@1236|Gammaproteobacteria,1XMFE@135619|Oceanospirillales	135619|Oceanospirillales	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR25158347_k127_3031605_0	1265503.KB905175_gene3946	1.139e-32	134.0	2CUHX@1|root,32SVD@2|Bacteria,1MZQ4@1224|Proteobacteria,1S8WU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
SRR25158347_k127_3035583_0	246194.CHY_0552	3.239e-13	78.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,24G83@186801|Clostridia,42IYE@68295|Thermoanaerobacterales	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31,Ubie_methyltran
SRR25158347_k127_3036046_0	290315.Clim_0553	0.0	1028.0	COG2838@1|root,COG2838@2|Bacteria,1FDPE@1090|Chlorobi	1090|Chlorobi	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
SRR25158347_k127_3041471_0	128390.XP_009470024.1	9.819e-05	55.0	28M43@1|root,2QTM0@2759|Eukaryota,39R11@33154|Opisthokonta,3BBTA@33208|Metazoa,3CZDB@33213|Bilateria,480I5@7711|Chordata,495WX@7742|Vertebrata,4GI4A@8782|Aves	33208|Metazoa	S	Golgin subfamily A member 4	GOLGA4	GO:0000138,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005802,GO:0005829,GO:0006810,GO:0006892,GO:0006893,GO:0007275,GO:0007399,GO:0008104,GO:0008150,GO:0008361,GO:0009987,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016192,GO:0017016,GO:0017137,GO:0019899,GO:0022008,GO:0022603,GO:0022604,GO:0030154,GO:0030306,GO:0030307,GO:0030516,GO:0031267,GO:0031344,GO:0031346,GO:0031984,GO:0031985,GO:0032501,GO:0032502,GO:0032535,GO:0033036,GO:0034613,GO:0040008,GO:0042802,GO:0042803,GO:0042886,GO:0043001,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045927,GO:0046983,GO:0048193,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050793,GO:0050794,GO:0051020,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051960,GO:0051962,GO:0060284,GO:0061387,GO:0061951,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0072659,GO:0090066,GO:0090150,GO:0098791,GO:0098876,GO:0120035,GO:1990778,GO:2000026	-	ko:K20283	-	-	-	-	ko00000,ko04131	-	-	-	GRIP
SRR25158347_k127_3044776_0	1348114.OM33_14655	6.872e-23	111.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RS27@1236|Gammaproteobacteria,2Q1GN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG4771 Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_3045071_0	529884.Rhola_00013560	3.816e-80	284.0	COG1226@1|root,COG1226@2|Bacteria,2GKPB@201174|Actinobacteria	201174|Actinobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid,TrkA_N
SRR25158347_k127_3049837_0	744872.Spica_1353	6.127e-85	298.0	COG0195@1|root,COG0195@2|Bacteria,2J624@203691|Spirochaetes	203691|Spirochaetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1,zf-ribbon_3
SRR25158347_k127_305626_0	1121129.KB903367_gene2842	2.151e-21	106.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,2FPEX@200643|Bacteroidia,22XJ9@171551|Porphyromonadaceae	976|Bacteroidetes	KT	Cache domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
SRR25158347_k127_3056786_0	502025.Hoch_1685	6.254e-44	165.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42PI0@68525|delta/epsilon subdivisions,2WJ79@28221|Deltaproteobacteria,2YUU7@29|Myxococcales	28221|Deltaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_3056786_1	755178.Cyan10605_0328	1.982e-22	105.0	COG2358@1|root,COG2358@2|Bacteria	2|Bacteria	G	TRAP transporter, solute receptor (TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158347_k127_3058135_0	35128.Thaps21124	8.375e-12	78.0	2ECT4@1|root,2SIJZ@2759|Eukaryota,2XB6B@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3060612_0	1480694.DC28_03670	1.226e-47	174.0	COG0379@1|root,COG0379@2|Bacteria,2JAE2@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158347_k127_3061632_0	517418.Ctha_2386	1.132e-75	261.0	COG1305@1|root,COG1305@2|Bacteria,1FEB8@1090|Chlorobi	1090|Chlorobi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158347_k127_3061632_1	102125.Xen7305DRAFT_00011200	6.951e-30	124.0	COG1073@1|root,COG1073@2|Bacteria,1G3WS@1117|Cyanobacteria,3VMP2@52604|Pleurocapsales	1117|Cyanobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,Hydrolase_4
SRR25158347_k127_306239_1	1415779.JOMH01000001_gene266	4.325e-72	254.0	COG4399@1|root,COG4399@2|Bacteria,1R404@1224|Proteobacteria,1S1H5@1236|Gammaproteobacteria,1X9DZ@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158347_k127_306239_0	665571.STHERM_c19010	1.366e-119	388.0	COG0480@1|root,COG0480@2|Bacteria,2J5M8@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158347_k127_3065453_0	439292.Bsel_0086	2.206e-76	265.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,26NH8@186821|Sporolactobacillaceae	91061|Bacilli	S	Large family of predicted nucleotide-binding domains	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158347_k127_3065453_1	404380.Gbem_1110	2.502e-24	106.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
SRR25158347_k127_3070669_0	111781.Lepto7376_1639	7.531e-123	412.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158347_k127_3072535_1	742765.HMPREF9457_03313	7.495e-60	216.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,27UTC@189330|Dorea	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158347_k127_3072535_0	247490.KSU1_C1426	1.266e-65	230.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158347_k127_3072853_2	640510.BC1001_2459	1.373e-20	103.0	2ACTP@1|root,312EI@2|Bacteria,1RFTU@1224|Proteobacteria,2W0F8@28216|Betaproteobacteria,1K22P@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3072853_1	1122604.JONR01000006_gene2716	1.244e-20	98.0	COG3427@1|root,COG3427@2|Bacteria,1N10Z@1224|Proteobacteria,1T3B2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_3072853_0	313606.M23134_07914	9.582e-27	111.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47KDC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_3080674_0	756272.Plabr_3528	2.408e-47	180.0	COG1215@1|root,COG1215@2|Bacteria,2IZ02@203682|Planctomycetes	203682|Planctomycetes	M	Involved in cell wall	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158347_k127_3080674_1	1158338.JNLJ01000005_gene1495	1.883e-13	74.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc,HATPase_c,Yop-YscD_cpl
SRR25158347_k127_3080674_2	1121481.AUAS01000001_gene4509	4.14e-10	61.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,47JT5@768503|Cytophagia	976|Bacteroidetes	S	COGs COG2220 Zn-dependent hydrolase of the beta-lactamase fold	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_308071_0	314345.SPV1_02087	1.365e-37	143.0	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria	1224|Proteobacteria	M	3D domain protein	DR0488	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158347_k127_308071_1	1144312.PMI09_02284	8.94e-28	120.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,4B7EK@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Phosphoglycolate phosphatase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158347_k127_3082432_1	340099.Teth39_0111	2.374e-41	162.0	COG0775@1|root,COG0775@2|Bacteria,1VCJY@1239|Firmicutes,24CRR@186801|Clostridia,42GAC@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM purine or other phosphorylase, family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
SRR25158347_k127_3082432_0	443144.GM21_0007	5.225e-84	285.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158347_k127_3082950_0	1123376.AUIU01000004_gene1153	7.236e-48	187.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158347_k127_3082950_1	7918.ENSLOCP00000021848	4.209e-45	183.0	COG0666@1|root,KOG4177@2759|Eukaryota,39UJT@33154|Opisthokonta,3BIQC@33208|Metazoa,3CZ1C@33213|Bilateria,487E2@7711|Chordata,497DI@7742|Vertebrata,4A2H2@7898|Actinopterygii	33208|Metazoa	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,CARD
SRR25158347_k127_3082950_2	1304888.ATWF01000001_gene2148	1.22e-06	57.0	COG3712@1|root,COG3712@2|Bacteria,2GGGY@200930|Deferribacteres	200930|Deferribacteres	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158347_k127_308497_0	246197.MXAN_5556	3.886e-175	555.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YU0I@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SRR25158347_k127_308497_1	1184267.A11Q_1509	1.729e-37	148.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2MTWM@213481|Bdellovibrionales,2WT1Y@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SRR25158347_k127_308497_2	1379698.RBG1_1C00001G1302	5.674e-07	56.0	COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158347_k127_3087165_3	291112.PAU_00693	4.842e-18	93.0	COG2314@1|root,COG2314@2|Bacteria,1NFDS@1224|Proteobacteria	1224|Proteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3087165_2	448385.sce5974	4.151e-64	228.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria,4340G@68525|delta/epsilon subdivisions,2X4F0@28221|Deltaproteobacteria,2YYWA@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158347_k127_3087165_0	373903.Hore_11000	4.741e-79	272.0	COG1235@1|root,COG1235@2|Bacteria,1V2ET@1239|Firmicutes,24E1K@186801|Clostridia,3WA8A@53433|Halanaerobiales	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SRR25158347_k127_3087165_1	1121396.KB893051_gene3457	3.345e-74	261.0	COG2267@1|root,COG2267@2|Bacteria,1QVW4@1224|Proteobacteria,42T0R@68525|delta/epsilon subdivisions,2WPP3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158347_k127_3092897_0	1173027.Mic7113_0758	6.565e-91	308.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_3095217_0	1122603.ATVI01000007_gene1430	5.729e-139	449.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1S01V@1236|Gammaproteobacteria,1X4DC@135614|Xanthomonadales	135614|Xanthomonadales	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158347_k127_3095217_1	1041930.Mtc_0426	9.055e-32	134.0	COG0438@1|root,arCOG01411@2157|Archaea,2Y8C9@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_3096713_1	197221.22294528	1.897e-18	95.0	COG0204@1|root,COG0204@2|Bacteria,1G0U3@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158347_k127_3096713_0	1353529.M899_2556	2.05e-24	103.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42PC4@68525|delta/epsilon subdivisions,2MTNU@213481|Bdellovibrionales,2WMG6@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158347_k127_3096785_0	1289135.A966_03830	8.777e-84	294.0	COG0664@1|root,COG0664@2|Bacteria,2J6CX@203691|Spirochaetes	203691|Spirochaetes	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3097167_1	1041826.FCOL_07650	9.891e-23	98.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia,2NUID@237|Flavobacterium	976|Bacteroidetes	H	Cytosine-specific methyltransferase	haeIIIM	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR25158347_k127_3097167_0	1158762.KB898064_gene1149	2.056e-70	250.0	COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,1RNU7@1236|Gammaproteobacteria,1WZA3@135613|Chromatiales	135613|Chromatiales	L	Domain of unknown function (DUF1738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738
SRR25158347_k127_3099014_0	526227.Mesil_0835	7.484e-96	326.0	COG0366@1|root,COG0366@2|Bacteria,1WI07@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.1,3.2.1.20	ko:K01176,ko:K01187	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00028,R00801,R00802,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
SRR25158347_k127_3100031_2	391596.PBAL39_14779	3.622e-07	52.0	COG0596@1|root,COG0596@2|Bacteria,4NFIB@976|Bacteroidetes,1IRMA@117747|Sphingobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	rsbQ	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158347_k127_3100031_0	272134.KB731324_gene5890	1.317e-108	380.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158347_k127_3100031_1	675806.VII_003129	3.701e-12	69.0	COG0642@1|root,COG0745@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,1T1Y4@1236|Gammaproteobacteria,1XTDR@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	chiS	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,Response_reg
SRR25158347_k127_310113_0	555088.DealDRAFT_2294	1.014e-63	229.0	COG0863@1|root,COG0863@2|Bacteria,1VDC7@1239|Firmicutes	1239|Firmicutes	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158347_k127_3102120_0	643867.Ftrac_0781	1.739e-73	258.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158347_k127_3102120_4	585531.HMPREF0063_10118	0.0004084	48.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4DV38@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_3102120_3	755178.Cyan10605_2156	0.0003156	48.0	COG1366@1|root,COG1366@2|Bacteria,1G6T5@1117|Cyanobacteria	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158347_k127_3102120_1	573413.Spirs_0320	2.967e-29	125.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_3102120_2	1122138.AQUZ01000050_gene7805	6.955e-29	119.0	COG0753@1|root,COG0753@2|Bacteria,2I04J@201174|Actinobacteria,4DVMU@85009|Propionibacteriales	201174|Actinobacteria	P	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_310287_1	1321815.HMPREF9193_01507	1.752e-12	68.0	COG1092@1|root,COG1092@2|Bacteria,2J5I4@203691|Spirochaetes	203691|Spirochaetes	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
SRR25158347_k127_310287_0	269798.CHU_2639	3.368e-179	567.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,47XY7@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158347_k127_3102938_1	665571.STHERM_c04900	6.157e-08	55.0	COG0085@1|root,COG0085@2|Bacteria,2J5JV@203691|Spirochaetes	203691|Spirochaetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158347_k127_3102938_0	1480694.DC28_14380	0.0	1223.0	COG0086@1|root,COG0086@2|Bacteria,2J5S7@203691|Spirochaetes	203691|Spirochaetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158347_k127_3105525_1	1254432.SCE1572_47360	2.248e-83	284.0	28J5X@1|root,2Z91N@2|Bacteria,1R6ZN@1224|Proteobacteria,438M4@68525|delta/epsilon subdivisions,2X1ZX@28221|Deltaproteobacteria,2YX8B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3105525_3	179408.Osc7112_5621	4.871e-19	92.0	COG1943@1|root,COG1943@2|Bacteria,1G6SS@1117|Cyanobacteria,1HBRS@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158347_k127_3105525_0	1123248.KB893321_gene551	4.217e-139	449.0	COG2141@1|root,COG2141@2|Bacteria,4NDW2@976|Bacteroidetes,1IRCN@117747|Sphingobacteriia	976|Bacteroidetes	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158347_k127_3105525_2	742767.HMPREF9456_01446	1.222e-30	125.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,2FSJ8@200643|Bacteroidia,22YEY@171551|Porphyromonadaceae	976|Bacteroidetes	M	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
SRR25158347_k127_3108024_1	1048983.EL17_15110	1.154e-24	106.0	COG4938@1|root,COG4938@2|Bacteria,4NMVA@976|Bacteroidetes,47RR9@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3696)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,DUF3696
SRR25158347_k127_3108024_0	1048983.EL17_15105	3.707e-93	312.0	COG1479@1|root,COG1479@2|Bacteria,4NRVQ@976|Bacteroidetes,47QKK@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
SRR25158347_k127_3108658_0	720554.Clocl_3859	1.173e-46	177.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WIKF@541000|Ruminococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158347_k127_3109536_1	761193.Runsl_3744	1.366e-21	104.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,47NJQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158347_k127_3109536_0	655815.ZPR_0318	1.987e-33	135.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1HWY3@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SRR25158347_k127_3111485_1	5932.XP_004029802.1	0.0004353	44.0	COG4642@1|root,KOG0231@2759|Eukaryota	2759|Eukaryota	DZ	MORN repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_3111485_0	909663.KI867149_gene3353	6.977e-164	538.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2MQCS@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbp2	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
SRR25158347_k127_3112051_0	929558.SMGD1_2622	1.782e-127	414.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2YMUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158347_k127_3112051_1	1121935.AQXX01000101_gene647	4.781e-20	94.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1XMY1@135619|Oceanospirillales	135619|Oceanospirillales	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158347_k127_3112394_2	1408433.JHXV01000048_gene3355	4.746e-11	66.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	mgtA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132	3.6.3.2	ko:K01531,ko:K16905	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.3.4	-	iSF_1195.SF4248	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158347_k127_3112394_1	1462527.CCDM010000004_gene3553	3.284e-23	108.0	COG1668@1|root,COG1668@2|Bacteria,1V2WV@1239|Firmicutes,4HG9R@91061|Bacilli,23KPT@182709|Oceanobacillus	91061|Bacilli	CP	transmembrane transport	-	-	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158347_k127_3112394_0	351160.RCIX1069	4.255e-103	342.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUAX@28890|Euryarchaeota	28890|Euryarchaeota	E	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K16907	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_3112394_3	403833.Pmob_1425	1.059e-05	53.0	2B141@1|root,31THU@2|Bacteria,2GD6E@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3115841_1	517418.Ctha_2571	3.639e-28	120.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1,GHL10,WG_beta_rep
SRR25158347_k127_3115841_0	338963.Pcar_1054	6.241e-52	188.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158347_k127_3115841_2	886379.AEWI01000013_gene2065	0.0001215	54.0	COG3203@1|root,COG3203@2|Bacteria,4NPPT@976|Bacteroidetes,2FTBM@200643|Bacteroidia,3XJZC@558415|Marinilabiliaceae	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3115841_3	1353529.M899_1922	0.000189	51.0	COG4254@1|root,COG4254@2|Bacteria,1NATC@1224|Proteobacteria,42X7Q@68525|delta/epsilon subdivisions,2WS9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158347_k127_3121380_0	1313301.AUGC01000004_gene2228	3.363e-51	194.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,4NGZ0@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,Response_reg
SRR25158347_k127_3121548_2	373994.Riv7116_6514	1.986e-45	171.0	COG1916@1|root,COG1916@2|Bacteria,1G4FN@1117|Cyanobacteria,1HS0G@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3121548_1	700598.Niako_5891	2.193e-166	538.0	COG1916@1|root,COG1916@2|Bacteria,4NEV1@976|Bacteroidetes,1IQSN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3121548_0	485918.Cpin_0756	9.757e-172	544.0	COG0714@1|root,COG0714@2|Bacteria,4NI8D@976|Bacteroidetes,1IRHM@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158347_k127_3121548_3	714943.Mucpa_2992	7.288e-08	61.0	COG1638@1|root,COG1638@2|Bacteria,4NU8D@976|Bacteroidetes,1ITIQ@117747|Sphingobacteriia	976|Bacteroidetes	G	TRAP-type C4-dicarboxylate transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3123192_0	153721.MYP_1529	1.974e-107	366.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,4NIDG@976|Bacteroidetes,47MI8@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
SRR25158347_k127_3123781_0	556261.HMPREF0240_03768	1.668e-28	119.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,36EDR@31979|Clostridiaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158347_k127_3123781_1	394503.Ccel_0487	1.983e-17	91.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,36DEG@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158347_k127_3126109_1	1347368.HG964403_gene4379	1.179e-11	71.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158347_k127_3126109_0	1449126.JQKL01000001_gene1339	1.403e-24	109.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia,268TQ@186813|unclassified Clostridiales	186801|Clostridia	N	Type III flagellar switch regulator (C-ring) FliN C-term	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
SRR25158347_k127_3128635_2	869209.Tresu_0472	2.952e-16	81.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
SRR25158347_k127_3128635_1	1121935.AQXX01000110_gene5495	2.78e-22	107.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XHNA@135619|Oceanospirillales	135619|Oceanospirillales	T	Methyl-accepting chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_9
SRR25158347_k127_3128635_0	1173027.Mic7113_6173	2.197e-90	319.0	COG2114@1|root,COG2202@1|root,COG4252@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2202@2|Bacteria,COG4252@2|Bacteria,COG5002@2|Bacteria,1G17N@1117|Cyanobacteria,1H8WZ@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc,PAS_4,PAS_9
SRR25158347_k127_312936_0	497964.CfE428DRAFT_5203	3.622e-20	99.0	COG3344@1|root,COG3344@2|Bacteria,46SUD@74201|Verrucomicrobia	2|Bacteria	L	Group II intron maturase-specific domain protein	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR25158347_k127_3131864_0	1487921.DP68_11685	2.337e-159	513.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,36DWA@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158347_k127_3131864_1	864702.OsccyDRAFT_2829	2.087e-84	285.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1H7FT@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Nucleos_tra2_C,Nucleos_tra2_N
SRR25158347_k127_3136331_0	932213.SPM24T3_16970	1.616e-11	78.0	COG4249@1|root,COG4249@2|Bacteria,1QX7K@1224|Proteobacteria,1T4W5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3136899_0	1128421.JAGA01000001_gene2038	3.597e-54	216.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,SpoIIE
SRR25158347_k127_3138061_1	1449063.JMLS01000030_gene407	1.342e-54	201.0	COG3176@1|root,COG3176@2|Bacteria,1VACP@1239|Firmicutes,4HUXB@91061|Bacilli,26SEZ@186822|Paenibacillaceae	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
SRR25158347_k127_3138061_2	5888.CAK87583	6.25e-08	63.0	2CYJJ@1|root,2S4T3@2759|Eukaryota,3ZBZ4@5878|Ciliophora	5878|Ciliophora	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3138061_0	243275.TDE_2274	2.341e-62	224.0	COG1655@1|root,COG1655@2|Bacteria,2J5GN@203691|Spirochaetes	203691|Spirochaetes	S	protein conserved in bacteria	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
SRR25158347_k127_3138081_0	984262.SGRA_1390	1.407e-52	199.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,1IWSD@117747|Sphingobacteriia	976|Bacteroidetes	M	COG2885 Outer membrane protein and related peptidoglycan-associated	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
SRR25158347_k127_3140456_0	28229.ND2E_0110	9.105e-06	56.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,1RRAJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	wzx	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158347_k127_3147854_1	1122917.KB899659_gene5456	3.538e-05	47.0	COG1208@1|root,COG4099@1|root,COG1208@2|Bacteria,COG4099@2|Bacteria,1UYYP@1239|Firmicutes,4I83Y@91061|Bacilli,26YTH@186822|Paenibacillaceae	91061|Bacilli	JM	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158347_k127_3147854_0	1250232.JQNJ01000001_gene1019	1.71e-44	167.0	2D2K4@1|root,32TD0@2|Bacteria,4NQ84@976|Bacteroidetes,1I1BN@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
SRR25158347_k127_31512_2	1353529.M899_2388	1.616e-34	134.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,43154@68525|delta/epsilon subdivisions,2MT61@213481|Bdellovibrionales,2WWCI@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRR25158347_k127_31512_3	1118055.CAGU01000043_gene1481	5.915e-15	77.0	COG0695@1|root,COG0695@2|Bacteria,1VEUW@1239|Firmicutes,24WNB@186801|Clostridia,22HJE@1570339|Peptoniphilaceae	186801|Clostridia	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158347_k127_31512_1	195103.CPF_1825	2.572e-107	358.0	COG0189@1|root,COG2918@1|root,COG0189@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,25ER3@186801|Clostridia,36URU@31979|Clostridiaceae	186801|Clostridia	HJ	belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase,RimK
SRR25158347_k127_31512_0	575588.ACPN01000120_gene2587	1.541e-109	372.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,3NK8B@468|Moraxellaceae	1236|Gammaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_2885	ATP-grasp_3,Glu_cys_ligase
SRR25158347_k127_3151435_0	1121335.Clst_0559	2.273e-43	165.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
SRR25158347_k127_3152964_0	1131266.ARWQ01000011_gene125	6.232e-27	124.0	COG1357@1|root,arCOG08793@1|root,arCOG03124@2157|Archaea,arCOG08793@2157|Archaea,41T9U@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158347_k127_3153469_1	314230.DSM3645_16255	4.855e-24	114.0	COG0840@1|root,COG0840@2|Bacteria,2IXQA@203682|Planctomycetes	2|Bacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	mcpA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_9
SRR25158347_k127_3153469_0	59374.Fisuc_1567	2.54e-96	331.0	COG1109@1|root,COG1109@2|Bacteria	2|Bacteria	G	phosphoglucosamine mutase activity	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158347_k127_3155857_1	305900.GV64_22305	4.155e-27	122.0	COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,1SB0I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158347_k127_3155857_0	43989.cce_4097	3.224e-49	182.0	COG0515@1|root,COG1672@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,3KHHW@43988|Cyanothece	1117|Cyanobacteria	T	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,Pkinase
SRR25158347_k127_3164238_0	1304878.AUGD01000021_gene3818	1.235e-59	223.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TUM8@28211|Alphaproteobacteria,3JXXF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_7,dCache_1
SRR25158347_k127_3165533_1	458817.Shal_0878	2.509e-16	86.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S30E@1236|Gammaproteobacteria,2Q9EK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	membrane lipoprotein lipid attachment site	lpoB	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
SRR25158347_k127_3165533_0	392500.Swoo_2673	5.662e-161	512.0	COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,1RNYT@1236|Gammaproteobacteria,2QCDQ@267890|Shewanellaceae	1236|Gammaproteobacteria	EH	Belongs to the TPP enzyme family	poxB	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158347_k127_3167124_2	82654.Pse7367_0933	1.771e-05	48.0	COG1104@1|root,COG1104@2|Bacteria,1G0YB@1117|Cyanobacteria,1H78Q@1150|Oscillatoriales	1117|Cyanobacteria	E	Cysteine sulfinate desulfinase cysteine desulfurase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158347_k127_3167124_0	1122146.AUHP01000011_gene283	1.453e-67	240.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_3167124_1	439235.Dalk_0873	2.823e-33	133.0	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria,2MPM5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
SRR25158347_k127_3167820_0	1131269.AQVV01000009_gene1116	2.892e-38	163.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158347_k127_3169633_0	192952.MM_2955	5.429e-50	200.0	arCOG02342@1|root,arCOG02342@2157|Archaea,2Y7NW@28890|Euryarchaeota,2NAB7@224756|Methanomicrobia	2157|Archaea	T	Pfam:Cache_1	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA_2,MCPsignal,PAS_3,PAS_9,dCache_1,sCache_3_3
SRR25158347_k127_3170377_1	1089550.ATTH01000001_gene354	1.073e-48	186.0	COG0318@1|root,COG0318@2|Bacteria,4PEW8@976|Bacteroidetes,1FJQI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158347_k127_3170377_2	1379270.AUXF01000004_gene2997	1.828e-32	130.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
SRR25158347_k127_3170377_0	237368.SCABRO_01045	3.151e-64	230.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_3172191_0	313606.M23134_02389	5.096e-68	250.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes,47THS@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
SRR25158347_k127_3172191_1	289376.THEYE_A0135	6.323e-12	73.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158347_k127_3174146_1	203124.Tery_2760	1.871e-25	120.0	COG4249@1|root,COG4249@2|Bacteria,1GPWG@1117|Cyanobacteria,1HBAE@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158347_k127_3174146_2	1444310.JANV01000111_gene2812	1.428e-22	98.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
SRR25158347_k127_3174146_0	1123400.KB904746_gene1315	4.155e-37	145.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRR25158347_k127_3175271_0	1125863.JAFN01000001_gene796	6.77e-29	132.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3175391_0	869213.JCM21142_104478	6.092e-32	128.0	COG0732@1|root,COG2827@1|root,COG0732@2|Bacteria,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,47X4H@768503|Cytophagia	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158347_k127_3175987_0	1219065.VPR01S_11_01760	6.991e-80	276.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XTMV@135623|Vibrionales	135623|Vibrionales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c,HisKA,Response_reg
SRR25158347_k127_3178305_0	317936.Nos7107_2198	3.709e-62	228.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase
SRR25158347_k127_3178305_1	756067.MicvaDRAFT_0280	1.437e-32	129.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_3178445_0	1128421.JAGA01000003_gene3623	4.477e-24	118.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	slt	-	-	ko:K07114,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.A.13.2.2,1.A.13.2.3	GH23	-	SLT,TPR_16,TPR_6
SRR25158347_k127_3182903_0	1236976.JCM16418_3440	1.14e-83	295.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1UEIC@1239|Firmicutes,4HDD8@91061|Bacilli,26RKT@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,Response_reg
SRR25158347_k127_3183592_1	523791.Kkor_0308	2.03e-08	56.0	COG1073@1|root,COG1073@2|Bacteria,1RKV2@1224|Proteobacteria,1S95V@1236|Gammaproteobacteria,1XRVU@135619|Oceanospirillales	135619|Oceanospirillales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3183592_0	1201288.M900_1457	2.177e-111	371.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MSRN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158347_k127_3184873_4	1146883.BLASA_0516	1.045e-06	61.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4ES5E@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_3184873_3	929703.KE386491_gene1072	3.921e-11	75.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47N39@768503|Cytophagia	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin,cNMP_binding
SRR25158347_k127_3184873_0	1173264.KI913949_gene4192	9.529e-111	372.0	COG1231@1|root,COG1231@2|Bacteria,1G3IC@1117|Cyanobacteria,1H8H3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158347_k127_3184873_2	926566.Terro_1167	1.322e-71	261.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158347_k127_3184873_1	1242864.D187_003296	1.572e-85	295.0	COG0845@1|root,COG0845@2|Bacteria,1PZ6R@1224|Proteobacteria	1224|Proteobacteria	M	COG0845 membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158347_k127_318530_2	1209989.TepiRe1_2583	5.472e-55	205.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,248B2@186801|Clostridia,42FDJ@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
SRR25158347_k127_318530_1	563040.Saut_0369	5.819e-70	246.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2YMBW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EG	membrane	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
SRR25158347_k127_318530_0	388413.ALPR1_16618	1.365e-72	248.0	COG3153@1|root,COG3153@2|Bacteria,4NP1G@976|Bacteroidetes,47QSB@768503|Cytophagia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,Zn_ribbon_2
SRR25158347_k127_3188196_0	489825.LYNGBM3L_09400	1.085e-88	299.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1H9BT@1150|Oscillatoriales	1117|Cyanobacteria	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_3188834_0	56780.SYN_00530	1.074e-47	179.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2MQHP@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158347_k127_3188834_1	565655.ECBG_00211	2.161e-13	79.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,4B079@81852|Enterococcaceae	91061|Bacilli	C	Iron-containing alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158347_k127_3189032_1	909663.KI867150_gene491	2.422e-13	74.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_3189032_0	880071.Fleli_3433	2.135e-51	189.0	COG2020@1|root,COG2020@2|Bacteria,4NJCI@976|Bacteroidetes,47QZH@768503|Cytophagia	976|Bacteroidetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158347_k127_3189400_2	518637.EUBIFOR_02475	7.952e-06	49.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,3VPCV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	tRNA nucleotidyltransferase poly(A) polymerase family protein	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158347_k127_3189400_1	1454007.JAUG01000013_gene2359	3.598e-43	179.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
SRR25158347_k127_3189400_0	862908.BMS_0446	6.699e-85	293.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2MT5M@213481|Bdellovibrionales,2WJE1@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158347_k127_3189814_1	573370.DMR_p1_00170	2.678e-09	61.0	COG4485@1|root,COG4485@2|Bacteria,1QAT5@1224|Proteobacteria,435A8@68525|delta/epsilon subdivisions,2X97C@28221|Deltaproteobacteria,2MFT4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3189814_0	373994.Riv7116_5480	1.781e-179	574.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HTTD@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_3190583_0	118005.AWNK01000007_gene805	2.066e-36	149.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_9,RsbU_N,SpoIIE
SRR25158347_k127_3190583_1	1123508.JH636449_gene7390	3.283e-28	129.0	COG2208@1|root,COG2905@1|root,COG2208@2|Bacteria,COG2905@2|Bacteria,2J1ZJ@203682|Planctomycetes	203682|Planctomycetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	CBS,SpoIIE
SRR25158347_k127_3190910_0	926561.KB900617_gene2134	3.501e-92	314.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WA9Z@53433|Halanaerobiales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158347_k127_3192912_0	1121396.KB893106_gene1818	2.043e-22	105.0	COG0823@1|root,COG4870@1|root,COG0823@2|Bacteria,COG4870@2|Bacteria,1R2H6@1224|Proteobacteria,42Y08@68525|delta/epsilon subdivisions,2WSRJ@28221|Deltaproteobacteria	2|Bacteria	U	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4214,LRR_5,Peptidase_C1,SLH
SRR25158347_k127_3193733_1	1033734.CAET01000028_gene4511	4.052e-13	80.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus	91061|Bacilli	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_3193733_0	545697.HMPREF0216_02373	3.861e-53	191.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,249NK@186801|Clostridia,36F32@31979|Clostridiaceae	186801|Clostridia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158347_k127_319487_1	927658.AJUM01000010_gene1352	4.236e-76	273.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2FRUD@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
SRR25158347_k127_319487_0	1499967.BAYZ01000182_gene4443	1.689e-84	293.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,2NR1F@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HD_5,HisKA,PAS_4,Response_reg
SRR25158347_k127_3195556_0	1319815.HMPREF0202_00212	1.304e-114	382.0	COG0466@1|root,COG0466@2|Bacteria,3789S@32066|Fusobacteria	32066|Fusobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158347_k127_3195939_1	1069533.Sinf_0464	9.118e-22	95.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22640	PALP
SRR25158347_k127_3195939_0	1042163.BRLA_c019270	2.869e-57	209.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,26RKI@186822|Paenibacillaceae	91061|Bacilli	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158347_k127_3199119_0	103690.17132441	2.159e-13	85.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HRWX@1161|Nostocales	1117|Cyanobacteria	Q	Peptidase M10 serralysin C terminal	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158347_k127_3204097_0	1089550.ATTH01000001_gene1848	5.712e-98	328.0	COG0175@1|root,COG0175@2|Bacteria,4NE9H@976|Bacteroidetes	976|Bacteroidetes	EH	Phosphoadenosine phosphosulfate reductase	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
SRR25158347_k127_3204812_0	889378.Spiaf_1256	1.626e-69	254.0	COG2114@1|root,COG2114@2|Bacteria,2J6HA@203691|Spirochaetes	203691|Spirochaetes	T	Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,Guanylate_cyc
SRR25158347_k127_3207248_0	153721.MYP_3773	4.94e-84	285.0	COG0604@1|root,COG0604@2|Bacteria,4NKEF@976|Bacteroidetes,47RHN@768503|Cytophagia	976|Bacteroidetes	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_3207248_2	1049564.TevJSym_bn00030	3.762e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1J67D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
SRR25158347_k127_3207248_1	526224.Bmur_0362	2.09e-19	87.0	COG1536@1|root,COG1536@2|Bacteria,2J5CI@203691|Spirochaetes	203691|Spirochaetes	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
SRR25158347_k127_3209849_0	1173028.ANKO01000144_gene1470	5.93e-62	218.0	COG2267@1|root,COG2267@2|Bacteria,1G4EA@1117|Cyanobacteria,1H9NV@1150|Oscillatoriales	1117|Cyanobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1
SRR25158347_k127_3209849_1	1288826.MSNKSG1_08378	8.4e-26	114.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,4650J@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	response regulator	rsbU	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
SRR25158347_k127_3210428_0	1192034.CAP_3531	3.491e-47	182.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,42MN7@68525|delta/epsilon subdivisions,2WIVK@28221|Deltaproteobacteria,2YYIN@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158347_k127_3210428_1	221027.JO40_12005	4.872e-08	62.0	COG3334@1|root,COG3334@2|Bacteria,2J66F@203691|Spirochaetes	203691|Spirochaetes	S	PFAM MgtE intracellular	flbB	-	-	ko:K02383	-	-	-	-	ko00000,ko02035	-	-	-	-
SRR25158347_k127_3213548_0	32057.KB217478_gene3617	1.557e-154	497.0	COG0467@1|root,COG0467@2|Bacteria,1G2XC@1117|Cyanobacteria,1HTZ7@1161|Nostocales	1117|Cyanobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158347_k127_3217544_0	1321778.HMPREF1982_00654	2.772e-30	134.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26B63@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PilJ,sCache_3_3
SRR25158347_k127_3217544_1	316067.Geob_0675	6.927e-20	93.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria,43VBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158347_k127_3218565_0	1158345.JNLL01000001_gene1904	8.494e-59	212.0	COG1912@1|root,COG1912@2|Bacteria,2G44H@200783|Aquificae	200783|Aquificae	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158347_k127_3218565_1	1121396.KB892901_gene2251	5.871e-35	135.0	COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,42P2N@68525|delta/epsilon subdivisions,2WM4M@28221|Deltaproteobacteria,2MJF1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease I	-	-	3.1.21.1	ko:K01150	-	-	-	-	ko00000,ko01000	-	-	-	Endonuclease_1
SRR25158347_k127_3219863_0	686340.Metal_1049	1.086e-70	265.0	COG0840@1|root,COG3920@1|root,COG0840@2|Bacteria,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158347_k127_3220121_1	768706.Desor_4225	0.000952	47.0	COG0695@1|root,COG0695@2|Bacteria,1VEHJ@1239|Firmicutes	1239|Firmicutes	O	PFAM Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158347_k127_3220121_0	1307761.L21SP2_2813	6.716e-15	83.0	COG1385@1|root,COG1385@2|Bacteria,2J81V@203691|Spirochaetes	203691|Spirochaetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158347_k127_3221322_0	869213.JCM21142_41472	1.453e-29	128.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,47SIE@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158347_k127_3222183_0	632335.Calkr_2111	1.988e-14	84.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
SRR25158347_k127_3226722_0	1380384.JADN01000004_gene1754	2.075e-85	294.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	2|Bacteria	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
SRR25158347_k127_323099_3	1192034.CAP_0257	1.206e-07	59.0	2DMJS@1|root,32S1R@2|Bacteria,1R3IU@1224|Proteobacteria,43DUK@68525|delta/epsilon subdivisions,2WYX8@28221|Deltaproteobacteria,2Z0UM@29|Myxococcales	28221|Deltaproteobacteria	S	GXWXG protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4334,GXWXG
SRR25158347_k127_323099_0	1380384.JADN01000003_gene999	4.914e-84	284.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,1HYTU@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158347_k127_323099_1	215803.DB30_2013	2.993e-34	140.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,438GF@68525|delta/epsilon subdivisions,2X3RA@28221|Deltaproteobacteria,2YWWZ@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial Ig-like domain (group 1)	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,LTD
SRR25158347_k127_323099_2	373903.Hore_04160	8.045e-14	80.0	COG4733@1|root,COG5498@1|root,COG4733@2|Bacteria,COG5498@2|Bacteria,1U7U3@1239|Firmicutes,248FT@186801|Clostridia	186801|Clostridia	M	hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Glyco_hydro_81
SRR25158347_k127_3233334_1	398767.Glov_0875	3.258e-63	229.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158347_k127_3233334_0	338963.Pcar_1247	2.725e-109	358.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,43SDU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PCRF	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158347_k127_3235433_0	1191523.MROS_1133	2.244e-121	398.0	COG0136@1|root,COG0136@2|Bacteria	2|Bacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	1.2.1.11,1.2.1.12	ko:K00133,ko:K00134	ko00010,ko00260,ko00261,ko00270,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04066,ko05010,map00010,map00260,map00261,map00270,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04066,map05010	M00001,M00002,M00003,M00016,M00017,M00018,M00033,M00165,M00166,M00308,M00525,M00526,M00527,M00552	R01061,R02291	RC00149,RC00684	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N,Semialdhyde_dh,Semialdhyde_dhC
SRR25158347_k127_3235433_1	1185876.BN8_01715	2.387e-05	48.0	COG3386@1|root,COG3386@2|Bacteria,4PNAW@976|Bacteroidetes,47MCX@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158347_k127_323597_2	1123229.AUBC01000001_gene1457	5.736e-09	60.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,3JSQ3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158347_k127_323597_1	1293054.HSACCH_00877	1.457e-23	102.0	COG4627@1|root,COG4627@2|Bacteria,1TUAF@1239|Firmicutes,25I7Q@186801|Clostridia,3WC67@53433|Halanaerobiales	186801|Clostridia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158347_k127_323597_0	1354300.AUQY01000002_gene1038	6.632e-39	162.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,22GKJ@1570339|Peptoniphilaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR25158347_k127_3235977_0	984262.SGRA_1633	1.071e-41	158.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,1IQQR@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
SRR25158347_k127_3235977_1	1237149.C900_01971	3.712e-25	118.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3237996_0	1123234.AUKI01000020_gene760	1.564e-183	600.0	COG3829@1|root,COG4251@1|root,COG5002@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_3237996_1	1267211.KI669560_gene647	4.278e-23	116.0	COG5002@1|root,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_9,Response_reg
SRR25158347_k127_3241630_0	1005058.UMN179_01128	3.61e-167	532.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1Y7P7@135625|Pasteurellales	135625|Pasteurellales	G	Aldolase	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158347_k127_3241630_1	1121948.AUAC01000002_gene1215	7.332e-33	135.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2V77P@28211|Alphaproteobacteria,43ZAS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3242336_1	644282.Deba_1097	1.16e-12	78.0	COG1752@1|root,COG1752@2|Bacteria,1REEJ@1224|Proteobacteria,4314S@68525|delta/epsilon subdivisions,2WWTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158347_k127_3242336_0	247490.KSU1_D1008	6.949e-60	214.0	COG2120@1|root,COG2120@2|Bacteria,2IZ0B@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158347_k127_3242336_2	530564.Psta_0548	3.305e-11	73.0	2C7TA@1|root,2Z9TR@2|Bacteria,2IXIJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3242766_1	1120951.AUBG01000002_gene1330	1.688e-29	121.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1HYN3@117743|Flavobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158347_k127_3242766_0	1101192.KB910516_gene1928	6.405e-106	353.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,1JT4H@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_3246621_0	1121285.AUFK01000002_gene86	3.744e-68	243.0	2C5QS@1|root,2ZK8N@2|Bacteria,4NPDX@976|Bacteroidetes,1I57C@117743|Flavobacteriia,3ZT1W@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3250236_1	570967.JMLV01000006_gene327	9.161e-06	49.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2JSQA@204441|Rhodospirillales	204441|Rhodospirillales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158347_k127_3250236_0	1177928.TH2_01020	1.16e-11	69.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2JSQA@204441|Rhodospirillales	204441|Rhodospirillales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158347_k127_3252541_0	59931.WH7805_10653	1.168e-45	181.0	COG2931@1|root,COG3210@1|root,COG4932@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,1GBCU@1117|Cyanobacteria	1117|Cyanobacteria	DMQZ	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,HemolysinCabind
SRR25158347_k127_3253190_0	631362.Thi970DRAFT_03258	6.147e-105	352.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1WXBI@135613|Chromatiales	135613|Chromatiales	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158347_k127_3253701_0	269799.Gmet_0456	2.159e-16	89.0	COG2227@1|root,COG4641@1|root,COG2227@2|Bacteria,COG4641@2|Bacteria,1RHSX@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158347_k127_3255866_0	2850.Phatr44546	9.625e-88	299.0	COG0667@1|root,KOG1575@2759|Eukaryota	2759|Eukaryota	C	oxidoreductase activity	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158347_k127_3257804_0	243231.GSU1246	6.704e-16	83.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria,43U36@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158347_k127_3257804_1	89187.ISM_14415	1.211e-06	56.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TQR9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158347_k127_3258243_0	941824.TCEL_00148	3.633e-163	522.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,36DBK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
SRR25158347_k127_3258585_0	903814.ELI_4124	7.136e-15	74.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25WQ2@186806|Eubacteriaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158347_k127_3258585_1	877418.ATWV01000011_gene66	2.491e-13	83.0	COG4733@1|root,COG4733@2|Bacteria,2JBHZ@203691|Spirochaetes	203691|Spirochaetes	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,fn3
SRR25158347_k127_3259228_0	744872.Spica_2841	1.435e-75	269.0	COG2172@1|root,COG2172@2|Bacteria,2J5ZY@203691|Spirochaetes	203691|Spirochaetes	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,cNMP_binding
SRR25158347_k127_3259228_1	867845.KI911784_gene23	1.845e-25	116.0	COG1454@1|root,COG1454@2|Bacteria,2GBSR@200795|Chloroflexi,375PH@32061|Chloroflexia	32061|Chloroflexia	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3259756_0	1168289.AJKI01000014_gene2077	1.621e-55	207.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,2FNMC@200643|Bacteroidia,3XIQ4@558415|Marinilabiliaceae	976|Bacteroidetes	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158347_k127_3259890_0	1120934.KB894413_gene3330	2.085e-05	49.0	COG1051@1|root,COG1051@2|Bacteria,2GP4Y@201174|Actinobacteria,4E6PU@85010|Pseudonocardiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158347_k127_3261824_7	1307759.JOMJ01000003_gene418	5.343e-14	72.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2MBK5@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158347_k127_3261824_1	1423806.JCM15457_2193	5.104e-72	249.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158347_k127_3261824_6	1499967.BAYZ01000114_gene2889	1.583e-26	111.0	COG0091@1|root,COG0091@2|Bacteria,2NPNW@2323|unclassified Bacteria	2|Bacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158347_k127_3261824_5	1218173.BALCAV_0205205	4.909e-38	144.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,1ZGXY@1386|Bacillus	91061|Bacilli	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158347_k127_3261824_0	573413.Spirs_0958	1.058e-106	352.0	COG0090@1|root,COG0090@2|Bacteria,2J5G3@203691|Spirochaetes	203691|Spirochaetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158347_k127_3261824_8	889378.Spiaf_0556	9.955e-13	72.0	COG0089@1|root,COG0089@2|Bacteria,2J85B@203691|Spirochaetes	203691|Spirochaetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158347_k127_3261824_3	66692.ABC0151	2.027e-43	166.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,1ZBG9@1386|Bacillus	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158347_k127_3261824_2	748449.Halha_0189	5.812e-58	208.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WAJF@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158347_k127_3261824_4	1187851.A33M_2384	5.564e-39	148.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,3FD79@34008|Rhodovulum	28211|Alphaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158347_k127_3266559_0	1121448.DGI_1240	3.437e-30	127.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42NNT@68525|delta/epsilon subdivisions,2WJDP@28221|Deltaproteobacteria,2M8A1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
SRR25158347_k127_3266673_2	1499967.BAYZ01000028_gene1279	6.097e-29	118.0	COG0635@1|root,COG0635@2|Bacteria,2NRKI@2323|unclassified Bacteria	2|Bacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,NUDIX,Radical_SAM
SRR25158347_k127_3266673_0	1499967.BAYZ01000028_gene1280	6.747e-67	235.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158347_k127_3266673_1	862908.BMS_0018	7.703e-42	163.0	COG0566@1|root,COG0566@2|Bacteria,1QQ53@1224|Proteobacteria,42R2I@68525|delta/epsilon subdivisions,2WWFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158347_k127_3270283_0	1121904.ARBP01000002_gene7178	5.612e-74	264.0	COG0642@1|root,COG2205@2|Bacteria,4NN26@976|Bacteroidetes,47U6C@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
SRR25158347_k127_3273825_0	643867.Ftrac_2777	8.073e-19	98.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	2.7.11.1	ko:K02450,ko:K12132	-	M00331	-	-	ko00000,ko00002,ko01000,ko01001,ko02044	9.B.42	-	-	CHAP,DUF1302,Glucosaminidase,Pkinase,SH3_3,SH3_5,SLH
SRR25158347_k127_3274512_1	765913.ThidrDRAFT_2360	3.732e-10	64.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1WYWY@135613|Chromatiales	135613|Chromatiales	J	Sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
SRR25158347_k127_3274512_2	1124982.MSI_12570	7.621e-10	70.0	COG3063@1|root,COG3063@2|Bacteria,2JBHH@203691|Spirochaetes	203691|Spirochaetes	NU	TPR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3274512_0	1123487.KB892868_gene1190	1.396e-18	91.0	2BIYM@1|root,32D6Z@2|Bacteria,1NDA6@1224|Proteobacteria,2W365@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3274683_2	537013.CLOSTMETH_01479	0.000132	48.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3WITZ@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158347_k127_3274683_0	1121333.JMLH01000026_gene1086	4.332e-67	240.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,3VPWN@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158347_k127_3274683_1	1313301.AUGC01000003_gene2088	1.889e-12	71.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158347_k127_327929_1	1211817.CCAT010000045_gene2954	2.874e-61	218.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,36W8D@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_327929_0	697281.Mahau_1317	9.701e-121	398.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_3285694_0	690850.Desaf_2181	9.176e-184	591.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2M7Y6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
SRR25158347_k127_3285694_1	558173.CDOO_07545	5.213e-82	281.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,22JQ5@1653|Corynebacteriaceae	201174|Actinobacteria	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158347_k127_328609_0	1117647.M5M_10930	4.47e-146	473.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J5MU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Pyruvate kinase, barrel domain	pykF	GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iECO103_1326.ECO103_1819,iPC815.YPO2393	PK,PK_C
SRR25158347_k127_3290270_1	313612.L8106_06454	1.048e-24	119.0	COG3779@1|root,COG3779@2|Bacteria,1G0J4@1117|Cyanobacteria,1H85K@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3290270_0	1304885.AUEY01000044_gene230	4.007e-33	145.0	COG1404@1|root,COG2911@1|root,COG3209@1|root,COG3420@1|root,COG3591@1|root,COG4677@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3420@2|Bacteria,COG3591@2|Bacteria,COG4677@2|Bacteria,1P8N9@1224|Proteobacteria,43DXZ@68525|delta/epsilon subdivisions,2X72D@28221|Deltaproteobacteria,2MNHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
SRR25158347_k127_3290940_0	631362.Thi970DRAFT_04078	3.425e-105	351.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X0I6@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
SRR25158347_k127_3291639_0	391615.ABSJ01000018_gene77	0.0003293	49.0	COG2239@1|root,COG2239@2|Bacteria,1RCPU@1224|Proteobacteria,1S1ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_329238_0	1304284.L21TH_1778	1.185e-33	140.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
SRR25158347_k127_3293441_0	742817.HMPREF9449_02000	3.23e-71	256.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FM28@200643|Bacteroidia,22W9A@171551|Porphyromonadaceae	976|Bacteroidetes	C	acyl-CoA dehydrogenase	acd	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_dehyd_C
SRR25158347_k127_3293441_1	1189612.A33Q_0445	1.012e-19	90.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRR25158347_k127_3295020_0	118163.Ple7327_4324	3.427e-59	225.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GD97@1117|Cyanobacteria,3VI2Q@52604|Pleurocapsales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,PAS_9,Pkinase,Response_reg
SRR25158347_k127_3296269_0	13349.G1X345	1.217e-21	103.0	COG0331@1|root,2QQJX@2759|Eukaryota,38EJX@33154|Opisthokonta,3NV76@4751|Fungi,3QMNX@4890|Ascomycota	4751|Fungi	I	fatty acid synthase	FAS1	GO:0001676,GO:0003674,GO:0003824,GO:0004312,GO:0004313,GO:0004314,GO:0004317,GO:0004318,GO:0004319,GO:0004321,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005811,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016409,GO:0016417,GO:0016418,GO:0016419,GO:0016420,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0072330,GO:1901576	2.3.1.86	ko:K00668	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R01404,R01624,R01626,R04428,R04430,R04535,R04537,R04544,R04568,R04725,R04954,R04956,R04959,R04962,R04964,R04965,R04967,R04970,R10700	RC00004,RC00029,RC00039,RC00052,RC00076,RC00120,RC00831,RC01095,RC02727,RC02857	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1,DUF1729,MaoC_dehydrat_N,MaoC_dehydratas,SAT
SRR25158347_k127_3299079_1	28072.Nos7524_2438	7.104e-07	57.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1GIZV@1117|Cyanobacteria,1HQPP@1161|Nostocales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158347_k127_3301026_0	96561.Dole_0114	5.187e-38	152.0	COG2186@1|root,COG2186@2|Bacteria,1Q9RS@1224|Proteobacteria,43DUF@68525|delta/epsilon subdivisions,2X8X4@28221|Deltaproteobacteria,2MNF1@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	GntR
SRR25158347_k127_3301236_1	580327.Tthe_1974	4.928e-07	59.0	COG5002@1|root,COG5002@2|Bacteria,1TQV5@1239|Firmicutes,248PK@186801|Clostridia,42J16@68295|Thermoanaerobacterales	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158347_k127_3301236_0	1237149.C900_01990	5.9e-35	138.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
SRR25158347_k127_3303598_0	1120965.AUBV01000001_gene3538	8.071e-54	194.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,47NQC@768503|Cytophagia	976|Bacteroidetes	FL	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158347_k127_3303598_1	867902.Ornrh_0622	0.000184	54.0	COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,1HWSM@117743|Flavobacteriia	976|Bacteroidetes	I	Long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
SRR25158347_k127_3303897_1	1274524.BSONL12_19936	5.532e-44	179.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus	91061|Bacilli	E	Sodium alanine symporter	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
SRR25158347_k127_3303897_0	526218.Sterm_2743	2.499e-76	264.0	COG0249@1|root,COG0249@2|Bacteria,378K4@32066|Fusobacteria	32066|Fusobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158347_k127_3304301_0	1121904.ARBP01000005_gene4845	3.862e-137	449.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158347_k127_3304301_1	489825.LYNGBM3L_09830	5.803e-88	310.0	COG0683@1|root,COG0683@2|Bacteria,1G1WJ@1117|Cyanobacteria,1H79U@1150|Oscillatoriales	1117|Cyanobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158347_k127_3306421_1	1242864.D187_004237	3.043e-06	49.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158347_k127_3306421_0	44060.JODL01000020_gene4862	1.161e-119	403.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2I931@201174|Actinobacteria	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRR25158347_k127_3308216_0	479431.Namu_3503	1.742e-11	77.0	2AQ5P@1|root,31FB4@2|Bacteria,2IRT0@201174|Actinobacteria,4EW1X@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3309002_0	1385935.N836_04315	4.216e-98	327.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,1H7UZ@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158347_k127_3309002_1	398579.Spea_4124	1.858e-19	91.0	COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,1RPY9@1236|Gammaproteobacteria,2Q92W@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SRR25158347_k127_3309603_0	1408164.MOLA814_00705	3.861e-66	233.0	COG1208@1|root,COG1208@2|Bacteria,1RDSE@1224|Proteobacteria	1224|Proteobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
SRR25158347_k127_3309603_1	497964.CfE428DRAFT_2541	2.096e-58	206.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158347_k127_330986_2	595537.Varpa_0639	4.127e-38	144.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2VPZW@28216|Betaproteobacteria,4ADI2@80864|Comamonadaceae	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158347_k127_330986_1	1304888.ATWF01000001_gene1549	2.607e-77	266.0	COG0081@1|root,COG0081@2|Bacteria,2GF5D@200930|Deferribacteres	200930|Deferribacteres	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158347_k127_330986_4	479437.Elen_2331	8.852e-20	96.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CVPQ@84998|Coriobacteriia	84998|Coriobacteriia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158347_k127_330986_3	1333998.M2A_3265	5.573e-38	146.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,4BQAY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158347_k127_330986_0	906968.Trebr_2301	1.857e-226	727.0	COG0085@1|root,COG0085@2|Bacteria,2J5JV@203691|Spirochaetes	203691|Spirochaetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158347_k127_3310563_1	1120919.AUBI01000019_gene3416	0.0002309	48.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158347_k127_3310563_0	1469613.JT55_06155	9.493e-109	358.0	COG2421@1|root,COG2421@2|Bacteria,1N12N@1224|Proteobacteria,2TV7V@28211|Alphaproteobacteria,3FEGY@34008|Rhodovulum	28211|Alphaproteobacteria	C	Acetamidase/Formamidase family	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR25158347_k127_3314539_0	411469.EUBHAL_02368	3.174e-31	131.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158347_k127_3314539_1	521045.Kole_1479	4.094e-05	54.0	COG1470@1|root,COG1470@2|Bacteria,2GCQ8@200918|Thermotogae	200918|Thermotogae	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
SRR25158347_k127_3315135_0	344747.PM8797T_26140	3.591e-50	191.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2IX09@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1080,FGE-sulfatase,Laminin_G_3,Pkinase
SRR25158347_k127_3315135_1	545694.TREPR_1642	3.436e-26	119.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
SRR25158347_k127_3315203_0	690597.JH730935_gene3332	4.701e-42	168.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T2CP@1236|Gammaproteobacteria,1YN5E@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Histidine kinase	ladS	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
SRR25158347_k127_3315314_0	103690.17131374	5.906e-67	245.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GRE7@1117|Cyanobacteria,1HRR4@1161|Nostocales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_3315517_0	1201290.M902_2805	2.819e-74	267.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_topoisoIV
SRR25158347_k127_3316016_0	944481.JAFP01000001_gene1002	7.237e-160	516.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2M70U@213113|Desulfurellales	28221|Deltaproteobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158347_k127_3316016_1	56780.SYN_01481	2.469e-32	128.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158347_k127_3317768_0	522772.Dacet_0977	2.391e-71	248.0	COG0488@1|root,COG0488@2|Bacteria,2GF1Z@200930|Deferribacteres	200930|Deferribacteres	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158347_k127_3317768_1	880073.Calab_0055	3.534e-15	80.0	COG5551@1|root,COG5551@2|Bacteria	2|Bacteria	S	defense response to virus	-	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
SRR25158347_k127_3318695_2	386456.JQKN01000001_gene2337	1.004e-27	121.0	COG0500@1|root,arCOG02702@2157|Archaea,2XWS9@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158347_k127_3318695_5	1129794.C427_1932	1.341e-05	53.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,464PG@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
SRR25158347_k127_3318695_0	580332.Slit_1984	1.094e-75	259.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158347_k127_3318695_1	1267535.KB906767_gene3570	7.619e-47	180.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	phoA	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR25158347_k127_3318695_3	1346330.M472_21675	1.91e-18	91.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Redoxin,Thioredoxin_8
SRR25158347_k127_3318695_4	545695.TREAZ_3274	3.499e-08	62.0	COG0642@1|root,COG2208@1|root,COG2205@2|Bacteria,COG2208@2|Bacteria,2J6U2@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_3320234_1	1255043.TVNIR_1739	2.074e-26	117.0	COG1652@1|root,COG3023@1|root,COG3179@1|root,COG1652@2|Bacteria,COG3023@2|Bacteria,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,1RZTY@1236|Gammaproteobacteria,1WZ8I@135613|Chromatiales	135613|Chromatiales	V	Chitinase class I	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_19
SRR25158347_k127_3320234_0	1255043.TVNIR_1739	1.804e-31	131.0	COG1652@1|root,COG3023@1|root,COG3179@1|root,COG1652@2|Bacteria,COG3023@2|Bacteria,COG3179@2|Bacteria,1R71F@1224|Proteobacteria,1RZTY@1236|Gammaproteobacteria,1WZ8I@135613|Chromatiales	135613|Chromatiales	V	Chitinase class I	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_19
SRR25158347_k127_3320234_2	387631.Asulf_01005	4.328e-05	51.0	arCOG03042@1|root,arCOG03042@2157|Archaea,2Y7NV@28890|Euryarchaeota	28890|Euryarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRR25158347_k127_3323156_4	305900.GV64_22300	1.106e-23	107.0	28MN9@1|root,2ZAXV@2|Bacteria,1PPEY@1224|Proteobacteria,1RYAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3323156_5	1123008.KB905695_gene2520	3.934e-19	93.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,4PKEU@976|Bacteroidetes,2FKZ0@200643|Bacteroidia,22WZ3@171551|Porphyromonadaceae	976|Bacteroidetes	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
SRR25158347_k127_3323156_2	266748.HY04_05035	4.215e-38	148.0	COG0457@1|root,COG0457@2|Bacteria,4NSXM@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158347_k127_3323156_0	497965.Cyan7822_0220	4.564e-61	214.0	COG0262@1|root,COG0262@2|Bacteria,1GPKF@1117|Cyanobacteria,3KITZ@43988|Cyanothece	1117|Cyanobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158347_k127_3323156_1	574087.Acear_1031	4.379e-51	188.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WAAT@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158347_k127_3323156_3	572479.Hprae_1998	3.406e-27	113.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WAAT@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158347_k127_3323322_0	946483.Cenrod_2440	8.219e-60	217.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE8,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg
SRR25158347_k127_3323358_0	392499.Swit_2934	0.0006033	49.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2U7B1@28211|Alphaproteobacteria,2K410@204457|Sphingomonadales	204457|Sphingomonadales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158347_k127_3324763_1	1291050.JAGE01000001_gene886	2.967e-05	53.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,3WN0Q@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3324763_0	1305737.JAFX01000001_gene586	1.002e-09	67.0	COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes	976|Bacteroidetes	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
SRR25158347_k127_3326678_1	1354300.AUQY01000002_gene1192	2.135e-16	85.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,22G2Z@1570339|Peptoniphilaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158347_k127_3326678_0	759914.BP951000_1063	3.66e-81	280.0	COG0215@1|root,COG0215@2|Bacteria,2J618@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158347_k127_3327935_1	765913.ThidrDRAFT_3746	3.205e-23	108.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1WXY4@135613|Chromatiales	135613|Chromatiales	M	PFAM Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158347_k127_3327935_0	869210.Marky_0752	7.523e-186	593.0	COG3387@1|root,COG3387@2|Bacteria,1WM7G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158347_k127_332936_0	448385.sce2064	4.838e-88	305.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2YUPX@29|Myxococcales	28221|Deltaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_332936_1	1116472.MGMO_107c00100	7.223e-09	59.0	28IA9@1|root,2Z9M7@2|Bacteria,1QTVI@1224|Proteobacteria,1T1IN@1236|Gammaproteobacteria,1XEN0@135618|Methylococcales	135618|Methylococcales	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
SRR25158347_k127_3332211_0	1288826.MSNKSG1_16116	2.333e-66	233.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,4669J@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_3332211_1	933801.Ahos_0003	5.811e-19	90.0	COG2154@1|root,arCOG02939@2157|Archaea,2XSDM@28889|Crenarchaeota	28889|Crenarchaeota	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158347_k127_3332471_1	316067.Geob_3335	4.718e-39	154.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158347_k127_3332471_2	1379858.N508_00346	1.058e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,2GESN@200930|Deferribacteres	200930|Deferribacteres	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
SRR25158347_k127_3332471_0	1148.1652925	2.745e-43	177.0	COG1808@1|root,COG1808@2|Bacteria,1G3Y7@1117|Cyanobacteria,1H5YN@1142|Synechocystis	1117|Cyanobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158347_k127_333259_0	1042376.AFPK01000036_gene1851	3.887e-114	375.0	COG0685@1|root,COG0685@2|Bacteria,4NJPU@976|Bacteroidetes	976|Bacteroidetes	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
SRR25158347_k127_333259_1	388413.ALPR1_14989	4.585e-34	133.0	2E3QV@1|root,32YNP@2|Bacteria,4NX04@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158347_k127_3335234_1	359.CN09_07895	2.05e-23	114.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,4BAI7@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158347_k127_3335234_0	204536.SULAZ_1196	8.463e-59	207.0	COG0442@1|root,COG0442@2|Bacteria,2G3SN@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158347_k127_333536_0	526224.Bmur_0974	1.784e-59	216.0	COG1198@1|root,COG1198@2|Bacteria,2J5B4@203691|Spirochaetes	203691|Spirochaetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158347_k127_333536_1	1455608.JDTH01000002_gene2009	0.0005045	47.0	COG1357@1|root,arCOG03128@2157|Archaea,2XU24@28890|Euryarchaeota,23T25@183963|Halobacteria	183963|Halobacteria	P	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide_3
SRR25158347_k127_3337417_0	218284.CCDN010000001_gene684	3.966e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158347_k127_3340125_0	383372.Rcas_0236	7.689e-27	124.0	COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,374TA@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158347_k127_3341802_0	349521.HCH_07005	1.076e-06	56.0	COG2844@1|root,COG4639@1|root,COG2844@2|Bacteria,COG4639@2|Bacteria,1MZH5@1224|Proteobacteria,1RZX8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PolyA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,HD
SRR25158347_k127_334204_1	237368.SCABRO_02742	1.299e-08	65.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158347_k127_334204_0	1121904.ARBP01000019_gene2775	2.363e-63	224.0	COG2935@1|root,COG2935@2|Bacteria,4NGKN@976|Bacteroidetes,47PCC@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the R-transferase family	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
SRR25158347_k127_3342363_2	237368.SCABRO_00148	6.586e-12	66.0	COG0673@1|root,COG0673@2|Bacteria,2J0EQ@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158347_k127_3342363_0	261292.Nit79A3_0552	1.183e-64	230.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,372G0@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
SRR25158347_k127_3342363_1	1408428.JNJP01000038_gene2666	1.717e-28	118.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,42QFJ@68525|delta/epsilon subdivisions,2WM97@28221|Deltaproteobacteria,2M957@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.20	ko:K01630	ko00053,map00053	-	R02754,R03277	RC00307,RC00435	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158347_k127_3343237_0	765910.MARPU_07720	2.601e-82	277.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WXMK@135613|Chromatiales	135613|Chromatiales	S	Polyphosphate AMP phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158347_k127_3343237_1	357809.Cphy_3876	7.511e-06	51.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,220T3@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158347_k127_3344008_0	545694.TREPR_3410	2.474e-07	61.0	COG4254@1|root,COG4254@2|Bacteria,2J6MW@203691|Spirochaetes	203691|Spirochaetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158347_k127_3345024_0	794903.OPIT5_07475	1.05e-36	150.0	2C130@1|root,30TQV@2|Bacteria,46XGK@74201|Verrucomicrobia,3K9V7@414999|Opitutae	414999|Opitutae	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRR25158347_k127_3350014_0	448385.sce3705	4.089e-33	139.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YVAG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158347_k127_3350703_0	1306174.JODP01000003_gene1937	1.791e-41	157.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria	201174|Actinobacteria	O	organic hydroperoxide resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158347_k127_3350703_1	1048983.EL17_16325	4.99e-07	52.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,4NG4N@976|Bacteroidetes,47JUR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.7.2	ko:K00367	ko00910,ko01120,map00910,map01120	M00531	R00791	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
SRR25158347_k127_3350924_0	1121904.ARBP01000012_gene1210	4.757e-199	628.0	COG0531@1|root,COG0531@2|Bacteria,4NH3Q@976|Bacteroidetes,47JXZ@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	eutP	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
SRR25158347_k127_3350924_1	1121904.ARBP01000004_gene929	3.875e-197	628.0	COG0470@1|root,COG0531@1|root,COG0470@2|Bacteria,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47KCI@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
SRR25158347_k127_3355016_0	865937.Gilli_1085	9.906e-121	394.0	COG2327@1|root,COG2327@2|Bacteria,4NEU1@976|Bacteroidetes,1HY8X@117743|Flavobacteriia,2P7K4@244698|Gillisia	976|Bacteroidetes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR25158347_k127_3357048_1	614083.AWQR01000023_gene154	3.266e-56	203.0	COG0546@1|root,COG0546@2|Bacteria,1R7C6@1224|Proteobacteria	1224|Proteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3357048_0	1175306.GWL_06230	6.971e-67	233.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2VR9I@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,Transket_pyr,Transketolase_C
SRR25158347_k127_3357082_1	1444309.JAQG01000021_gene1364	2.184e-23	102.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,2779W@186822|Paenibacillaceae	91061|Bacilli	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.7.13.3	ko:K02491	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR25158347_k127_3357082_0	177437.HRM2_43550	1.405e-35	149.0	COG0784@1|root,COG2198@1|root,COG4936@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4936@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria,2MPK6@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sensory domain found in PocR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
SRR25158347_k127_3358189_1	91464.S7335_3707	6.337e-81	273.0	COG1249@1|root,COG1249@2|Bacteria,1G0W0@1117|Cyanobacteria,1GZP1@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_3358189_0	1353529.M899_2252	5.728e-185	588.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2MSTB@213481|Bdellovibrionales,2WJ2C@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,HEAT_2,Peptidase_M1
SRR25158347_k127_335950_0	443218.AS9A_1086	1.061e-56	210.0	2E963@1|root,333ES@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
SRR25158347_k127_3359574_0	1123376.AUIU01000016_gene283	5.129e-98	334.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158347_k127_3359609_1	572480.Arnit_2927	3e-19	87.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2YNIP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	NAD dependent epimerase dehydratase family	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158347_k127_3359609_0	572480.Arnit_2925	6.047e-143	460.0	COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2YTQP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158347_k127_3359609_2	1124780.ANNU01000062_gene570	1.855e-13	71.0	COG1208@1|root,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,47QXN@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
SRR25158347_k127_3360532_0	1123274.KB899413_gene841	5.411e-09	63.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,2J5P8@203691|Spirochaetes	203691|Spirochaetes	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
SRR25158347_k127_3366816_0	555079.Toce_1390	2.1e-42	171.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,42EPS@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM glycosyl transferase, family 51	pbpA1	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_3366831_0	317936.Nos7107_1366	4.921e-207	662.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	4.6.1.1	ko:K01768,ko:K07216	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,PAS_9,Pkinase,Response_reg
SRR25158347_k127_3369952_0	926549.KI421517_gene1451	9.257e-89	304.0	COG2203@1|root,COG2203@2|Bacteria,4NE84@976|Bacteroidetes,47K2E@768503|Cytophagia	976|Bacteroidetes	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3370201_1	631454.N177_2501	6.542e-120	394.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,1JNDT@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_3370201_0	3847.GLYMA18G52430.2	1.73e-147	489.0	COG0567@1|root,KOG0450@2759|Eukaryota,37MIR@33090|Viridiplantae,3GGCN@35493|Streptophyta,4JFA4@91835|fabids	35493|Streptophyta	C	2-oxoglutarate dehydrogenase	-	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005947,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009353,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030062,GO:0031974,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0070013,GO:0071704,GO:0072350,GO:0098798,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158347_k127_3372196_1	1173028.ANKO01000014_gene1006	1.08e-15	87.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H8H6@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_3372196_0	1121403.AUCV01000003_gene1766	6.625e-35	145.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria,2MJS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SRR25158347_k127_3373307_0	1123228.AUIH01000013_gene211	9.626e-13	76.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
SRR25158347_k127_3374328_1	1223410.KN050846_gene192	3.057e-07	58.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,1HY21@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX amino terminal protease family	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158347_k127_3374328_0	720555.BATR1942_18960	3.522e-61	220.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158347_k127_337483_0	1121918.ARWE01000001_gene2746	1.931e-132	431.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,43SCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158347_k127_337483_2	929703.KE386491_gene848	1.355e-05	48.0	2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_337483_4	1087481.AGFX01000013_gene3067	0.0005621	42.0	2BKI8@1|root,32EZF@2|Bacteria,1TZNM@1239|Firmicutes,4I8XU@91061|Bacilli,270PJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_337483_1	448385.sce2775	3.021e-06	54.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,42NMF@68525|delta/epsilon subdivisions,2WIJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158347_k127_3374875_0	1239962.C943_04510	1.087e-86	308.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,4NDXU@976|Bacteroidetes,47XWU@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y
SRR25158347_k127_3377590_0	203122.Sde_3060	8.365e-63	224.0	COG5285@1|root,COG5285@2|Bacteria,1RC3C@1224|Proteobacteria,1S4A7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158347_k127_3377590_1	1499967.BAYZ01000028_gene1278	1.534e-35	139.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158347_k127_3381220_0	1170562.Cal6303_4596	1.021e-130	437.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1HJ09@1161|Nostocales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
SRR25158347_k127_3384984_0	402777.KB235903_gene2602	1.222e-84	304.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GC6Z@1117|Cyanobacteria,1H6Y9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_3387313_0	519989.ECTPHS_06737	2.513e-92	308.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales	135613|Chromatiales	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,RLAN,RimK
SRR25158347_k127_3387313_1	1379698.RBG1_1C00001G0989	2.69e-06	55.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact
SRR25158347_k127_338744_0	1250278.JQNQ01000001_gene1145	6.763e-05	47.0	COG3668@1|root,COG3668@2|Bacteria,4NQMN@976|Bacteroidetes,1I3PI@117743|Flavobacteriia	976|Bacteroidetes	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158347_k127_3389491_1	1122604.JONR01000020_gene518	2.804e-08	64.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,1SBRG@1236|Gammaproteobacteria,1X6ZH@135614|Xanthomonadales	135614|Xanthomonadales	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
SRR25158347_k127_3389491_0	1296415.JACC01000001_gene3510	5.258e-18	87.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1I8SB@117743|Flavobacteriia,2YJT5@290174|Aquimarina	976|Bacteroidetes	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158347_k127_3389804_0	1122212.AULO01000014_gene1246	6.672e-176	558.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XH22@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158347_k127_3389804_1	246197.MXAN_3297	4.339e-53	209.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2YXGK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158347_k127_3391361_0	671143.DAMO_0934	8.986e-64	225.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ymfI	-	1.1.1.100,1.3.1.28	ko:K00059,ko:K00216,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	M00083,M00572	R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158347_k127_3393290_0	1444309.JAQG01000164_gene1835	2.208e-156	503.0	COG3864@1|root,COG3864@2|Bacteria,1TQ6J@1239|Firmicutes,4HDI3@91061|Bacilli,26WEV@186822|Paenibacillaceae	91061|Bacilli	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
SRR25158347_k127_3397749_8	1408428.JNJP01000148_gene976	3.866e-09	66.0	2C377@1|root,2Z7II@2|Bacteria,1NNYY@1224|Proteobacteria,42YAN@68525|delta/epsilon subdivisions,2WUGQ@28221|Deltaproteobacteria,2MA6G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	P22 coat protein - gene protein 5	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
SRR25158347_k127_3397749_12	1499685.CCFJ01000055_gene1936	3.751e-05	55.0	2DCCD@1|root,2ZDNK@2|Bacteria,1V1YS@1239|Firmicutes,4IA28@91061|Bacilli,1ZIHA@1386|Bacillus	91061|Bacilli	S	Phage minor capsid protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Phage_min_cap2
SRR25158347_k127_3397749_14	237368.SCABRO_02736	8.006e-05	54.0	COG1749@1|root,COG1749@2|Bacteria,2IYJT@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
SRR25158347_k127_3397749_0	929703.KE386491_gene1258	4.328e-55	222.0	COG3941@1|root,COG3941@2|Bacteria,4PP2D@976|Bacteroidetes,47YF4@768503|Cytophagia	976|Bacteroidetes	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3397749_7	1191460.F959_02620	1.13e-10	72.0	COG5295@1|root,COG5295@2|Bacteria,1N338@1224|Proteobacteria,1RPXV@1236|Gammaproteobacteria,3NIF1@468|Moraxellaceae	1236|Gammaproteobacteria	UW	Coiled stalk of trimeric autotransporter adhesin	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,YadA_anchor,YadA_head,YadA_stalk
SRR25158347_k127_3397749_9	1476973.JMMB01000004_gene3377	9.684e-07	56.0	COG1357@1|root,COG1357@2|Bacteria,1TR7Y@1239|Firmicutes,2482A@186801|Clostridia,25TQG@186804|Peptostreptococcaceae	186801|Clostridia	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158347_k127_3397749_10	887929.HMP0721_1276	1.32e-06	56.0	COG1044@1|root,COG1044@2|Bacteria,1V8ZN@1239|Firmicutes,24JT1@186801|Clostridia	186801|Clostridia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3397749_11	1242969.ATCC51562_1602	1.018e-05	56.0	2DBI5@1|root,2Z9EN@2|Bacteria,1PMHG@1224|Proteobacteria,42PJZ@68525|delta/epsilon subdivisions,2YN9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	PDDEXK-like domain of unknown function (DUF3799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3799
SRR25158347_k127_3397749_13	1538644.KO02_11585	5.465e-05	50.0	2ERDD@1|root,33IZ1@2|Bacteria,4NYWK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3397749_1	1150474.JQJI01000006_gene809	4.137e-53	203.0	COG1783@1|root,COG1783@2|Bacteria,2GE2Z@200918|Thermotogae	200918|Thermotogae	S	Terminase RNAseH like domain	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
SRR25158347_k127_3397749_15	69319.XP_008556365.1	0.0002295	48.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3
SRR25158347_k127_3397749_3	1034347.CAHJ01000034_gene3989	3.843e-39	155.0	COG0175@1|root,COG0175@2|Bacteria,1TQBQ@1239|Firmicutes,4HD3W@91061|Bacilli,1ZFD1@1386|Bacillus	91061|Bacilli	EH	sulfate reduction	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
SRR25158347_k127_3397749_2	63737.Npun_R2590	8.639e-42	158.0	2CPKU@1|root,32SJD@2|Bacteria,1G8WS@1117|Cyanobacteria,1HSH3@1161|Nostocales	1117|Cyanobacteria	L	3' exoribonuclease, RNase T-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF5051
SRR25158347_k127_3406506_1	326298.Suden_1970	4.804e-64	222.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2YTC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158347_k127_3406506_0	326298.Suden_1971	1.813e-68	237.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
SRR25158347_k127_3407758_1	759914.BP951000_1957	1.016e-11	68.0	COG0125@1|root,COG0125@2|Bacteria,2J765@203691|Spirochaetes	203691|Spirochaetes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158347_k127_3407758_0	1121936.AUHI01000008_gene532	6.811e-55	199.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli	91061|Bacilli	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	caiE	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158347_k127_3407758_2	452637.Oter_0687	2.289e-05	54.0	COG1463@1|root,COG1463@2|Bacteria,46W05@74201|Verrucomicrobia,3K88C@414999|Opitutae	414999|Opitutae	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158347_k127_3409744_0	1191523.MROS_1635	1.613e-239	761.0	COG0046@1|root,COG0046@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158347_k127_3409744_1	1304284.L21TH_1652	1.87e-84	295.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,36DGD@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158347_k127_341206_1	1304885.AUEY01000011_gene1770	7.077e-22	103.0	2AEFS@1|root,314AU@2|Bacteria,1RKTV@1224|Proteobacteria,42YDD@68525|delta/epsilon subdivisions,2WUI4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_341206_0	1304885.AUEY01000011_gene1771	7.746e-70	248.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,42YBW@68525|delta/epsilon subdivisions,2WUJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_3412734_0	7668.SPU_008437-tr	2.299e-48	190.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
SRR25158347_k127_3412734_1	670307.HYPDE_29208	5.091e-37	142.0	COG0614@1|root,COG0614@2|Bacteria,1PK1C@1224|Proteobacteria,2TRF4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158347_k127_3414102_0	90814.KL370892_gene2277	4.432e-56	198.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,462A4@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158347_k127_3415633_0	589865.DaAHT2_2426	1.56e-83	286.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,42M30@68525|delta/epsilon subdivisions,2WKRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158347_k127_342217_0	1168034.FH5T_20815	1.968e-52	197.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,4PN7F@976|Bacteroidetes,2G14N@200643|Bacteroidia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_342217_1	1499967.BAYZ01000061_gene5978	1.936e-33	139.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_3423279_0	32057.KB217478_gene3884	2.582e-88	293.0	COG0714@1|root,COG0714@2|Bacteria,1GD74@1117|Cyanobacteria,1HQHU@1161|Nostocales	1117|Cyanobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158347_k127_3423279_1	665571.STHERM_c06300	3.873e-87	297.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	ndh	-	1.6.99.3	ko:K03885,ko:K10716	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Abhydrolase_6,Ion_trans,Pyr_redox_2,cNMP_binding
SRR25158347_k127_3425740_0	1123355.JHYO01000004_gene2561	4.91e-41	158.0	COG0703@1|root,COG0703@2|Bacteria	2|Bacteria	F	shikimate kinase activity	aroK	-	2.7.1.71,4.2.3.4	ko:K00891,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158347_k127_3427787_1	1385513.N780_05350	1.508e-28	117.0	COG4446@1|root,COG4446@2|Bacteria,1VDZG@1239|Firmicutes,4HN9R@91061|Bacilli,2YAKS@289201|Pontibacillus	91061|Bacilli	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
SRR25158347_k127_3427787_2	1201293.AKXQ01000003_gene2601	4.452e-07	62.0	COG2604@1|root,COG2604@2|Bacteria,1MUQQ@1224|Proteobacteria,1RZPR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
SRR25158347_k127_3427787_0	522772.Dacet_1700	3.73e-118	389.0	COG0488@1|root,COG0488@2|Bacteria,2GFC2@200930|Deferribacteres	200930|Deferribacteres	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158347_k127_3432290_0	744872.Spica_1520	1.062e-94	329.0	COG1315@1|root,COG1315@2|Bacteria,2J5S8@203691|Spirochaetes	203691|Spirochaetes	L	COGs COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,Jag_N
SRR25158347_k127_343399_0	526224.Bmur_1068	6.177e-84	282.0	COG1077@1|root,COG1077@2|Bacteria,2J59M@203691|Spirochaetes	203691|Spirochaetes	D	cell shape determining protein, MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158347_k127_343399_1	929556.Solca_2574	1.773e-13	74.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1INMM@117747|Sphingobacteriia	976|Bacteroidetes	S	iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
SRR25158347_k127_3434177_0	318167.Sfri_0198	2.525e-16	88.0	COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,1RPY9@1236|Gammaproteobacteria,2Q92W@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158347_k127_343476_0	485918.Cpin_2471	3.046e-86	294.0	COG0656@1|root,COG0656@2|Bacteria,4NK47@976|Bacteroidetes,1IWTP@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_343476_1	1190603.AJYD01000029_gene4451	6.036e-33	130.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria,1XSU0@135623|Vibrionales	135623|Vibrionales	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158347_k127_3435030_0	211165.AJLN01000098_gene5145	9.494e-98	335.0	COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1GHJE@1117|Cyanobacteria,1JMX7@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_3435030_1	760142.Hipma_0949	3.092e-17	89.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M68Y@213113|Desulfurellales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158347_k127_3439322_0	313628.LNTAR_20223	2.257e-32	135.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRR25158347_k127_3440528_0	1121904.ARBP01000026_gene652	1.931e-162	535.0	COG2268@1|root,COG2268@2|Bacteria,4NFJ2@976|Bacteroidetes,47JPT@768503|Cytophagia	976|Bacteroidetes	S	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_3440528_2	1121957.ATVL01000006_gene3061	6.8e-11	71.0	28M6W@1|root,2ZAKF@2|Bacteria,4NJT7@976|Bacteroidetes,47R78@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
SRR25158347_k127_3440528_1	760192.Halhy_2373	2.425e-37	142.0	COG1487@1|root,COG1487@2|Bacteria,4NSWG@976|Bacteroidetes	976|Bacteroidetes	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158347_k127_3440528_3	760192.Halhy_2373	0.0001133	44.0	COG1487@1|root,COG1487@2|Bacteria,4NSWG@976|Bacteroidetes	976|Bacteroidetes	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158347_k127_3440985_0	394503.Ccel_1545	3.64e-44	173.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA
SRR25158347_k127_3442552_0	1500890.JQNL01000001_gene53	5.551e-32	128.0	COG2304@1|root,COG2304@2|Bacteria,1NT48@1224|Proteobacteria,1SMV0@1236|Gammaproteobacteria,1XA32@135614|Xanthomonadales	135614|Xanthomonadales	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3442552_1	631362.Thi970DRAFT_03969	4.088e-25	115.0	2CX9T@1|root,32T1J@2|Bacteria,1NEF4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3448007_1	865937.Gilli_0725	9.705e-52	185.0	COG2244@1|root,COG2244@2|Bacteria,4NFKD@976|Bacteroidetes,1HZ63@117743|Flavobacteriia,2P6FR@244698|Gillisia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158347_k127_3448007_0	865937.Gilli_0726	2.034e-81	273.0	28IN0@1|root,2Z8NG@2|Bacteria,4NNZ4@976|Bacteroidetes,1HXHT@117743|Flavobacteriia,2P7EX@244698|Gillisia	976|Bacteroidetes	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	2.4.1.152,2.4.1.65	ko:K20151	-	-	-	-	ko00000,ko01000,ko01003	-	GT10	-	Glyco_transf_10
SRR25158347_k127_3449573_0	1121930.AQXG01000002_gene1988	7.433e-49	185.0	COG0739@1|root,COG0739@2|Bacteria,4NPNT@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_3451825_1	36870.25166221	2.378e-14	83.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158347_k127_3451825_0	406817.XNC1_4035	9.545e-28	127.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,AAA_30,UvrD_C_2
SRR25158347_k127_3457719_0	105425.BBPL01000045_gene3219	4.327e-57	200.0	COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria,2NI0T@228398|Streptacidiphilus	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3457719_1	391615.ABSJ01000034_gene1070	6.232e-48	179.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RSCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Saccharopine dehydrogenase	lys	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158347_k127_3458037_0	1131269.AQVV01000025_gene2327	8.559e-38	153.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HTH_31
SRR25158347_k127_3458037_1	111781.Lepto7376_2461	5.791e-25	111.0	COG1408@1|root,COG1408@2|Bacteria,1GHEI@1117|Cyanobacteria	1117|Cyanobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158347_k127_3458901_1	1123405.AUMM01000042_gene308	2.58e-66	229.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26NIS@186821|Sporolactobacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158347_k127_3458901_0	293826.Amet_0007	1.006e-191	614.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158347_k127_3458936_0	215803.DB30_5313	8.09e-103	345.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales	28221|Deltaproteobacteria	S	Major facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158347_k127_3461987_1	1453505.JASY01000001_gene3755	1.489e-21	100.0	COG1073@1|root,COG1073@2|Bacteria,4NGG4@976|Bacteroidetes,1IMUE@117743|Flavobacteriia,2NUXE@237|Flavobacterium	976|Bacteroidetes	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,Hydrolase_4
SRR25158347_k127_3461987_0	1168034.FH5T_20810	1.359e-31	127.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FRUD@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,Response_reg
SRR25158347_k127_3462772_0	448385.sce8838	2.923e-49	183.0	COG0431@1|root,COG0431@2|Bacteria,1RGV1@1224|Proteobacteria	1224|Proteobacteria	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158347_k127_346326_1	1122915.AUGY01000022_gene6713	0.0001279	52.0	COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,4HDVB@91061|Bacilli,26WR8@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
SRR25158347_k127_346326_0	765913.ThidrDRAFT_4598	3.608e-19	94.0	COG0515@1|root,COG0515@2|Bacteria,1N79H@1224|Proteobacteria,1S6V2@1236|Gammaproteobacteria,1WZK3@135613|Chromatiales	135613|Chromatiales	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
SRR25158347_k127_3463608_0	1333998.M2A_1970	6.702e-100	338.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,4BPQ9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158347_k127_3464542_0	500635.MITSMUL_05617	0.0001301	52.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4H2V8@909932|Negativicutes	909932|Negativicutes	S	Hydrolase carbon-nitrogen family	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158347_k127_347219_2	1158318.ATXC01000001_gene636	1.202e-23	102.0	COG0019@1|root,COG0019@2|Bacteria,2G3VG@200783|Aquificae	200783|Aquificae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158347_k127_347219_0	1239962.C943_03898	5.145e-89	305.0	COG0151@1|root,COG0151@2|Bacteria,4NK50@976|Bacteroidetes,47TMM@768503|Cytophagia	976|Bacteroidetes	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158347_k127_347219_3	648996.Theam_0935	1.012e-15	79.0	2EBCA@1|root,335D0@2|Bacteria,2G49N@200783|Aquificae	200783|Aquificae	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158347_k127_347219_1	395493.BegalDRAFT_3053	8.714e-46	175.0	COG2340@1|root,COG2340@2|Bacteria,1N02F@1224|Proteobacteria	1224|Proteobacteria	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158347_k127_3475131_1	1392502.JNIO01000002_gene270	0.00085	45.0	COG5464@1|root,COG5464@2|Bacteria,1V828@1239|Firmicutes,4H96B@909932|Negativicutes	2|Bacteria	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SRR25158347_k127_3476540_0	56110.Oscil6304_2238	9.597e-114	384.0	COG0515@1|root,COG2114@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
SRR25158347_k127_3476540_1	215803.DB30_5174	1.097e-05	57.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,1PEIB@1224|Proteobacteria,439WA@68525|delta/epsilon subdivisions,2X5AJ@28221|Deltaproteobacteria,2YWZV@29|Myxococcales	28221|Deltaproteobacteria	N	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
SRR25158347_k127_3481733_1	1121930.AQXG01000004_gene2954	8.514e-07	52.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_3485340_0	653733.Selin_1273	2.604e-23	114.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
SRR25158347_k127_3485340_1	1121904.ARBP01000005_gene4640	7.086e-10	61.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes,47THS@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
SRR25158347_k127_3488062_3	1168065.DOK_03348	2.892e-15	79.0	COG3447@1|root,COG4191@1|root,COG3447@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T1YU@1236|Gammaproteobacteria,1J4VA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	MASE1	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	CHASE,HATPase_c,HisKA,Hpt,MASE1,Reg_prop,Response_reg,Y_Y_Y
SRR25158347_k127_3488062_2	1124780.ANNU01000005_gene2378	6.795e-62	222.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,47JB4@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_3488062_1	653733.Selin_0632	2.469e-136	445.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
SRR25158347_k127_3488062_0	759914.BP951000_0585	2.256e-204	650.0	COG1061@1|root,COG1061@2|Bacteria,2J6EB@203691|Spirochaetes	203691|Spirochaetes	L	DNA or RNA helicase of superfamily II	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158347_k127_3488623_0	388467.A19Y_3367	1.944e-88	304.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1H9QG@1150|Oscillatoriales	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158347_k127_349402_27	1003200.AXXA_29545	0.000336	52.0	COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2VURA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
SRR25158347_k127_349402_25	94624.Bpet4429	2.888e-07	62.0	2DNUP@1|root,32Z8X@2|Bacteria,1QV4C@1224|Proteobacteria,2W3EY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_349402_15	314345.SPV1_02707	1.124e-14	83.0	COG3778@1|root,COG3778@2|Bacteria,1N3CF@1224|Proteobacteria	1224|Proteobacteria	S	Tail protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
SRR25158347_k127_349402_6	715226.ABI_08490	6.255e-51	194.0	COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria,2U8GE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158347_k127_349402_17	1229485.AMYV01000023_gene3049	7.132e-13	74.0	COG4381@1|root,COG4381@2|Bacteria,1N954@1224|Proteobacteria,1S7NU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage protein GP46	-	-	-	-	-	-	-	-	-	-	-	-	GP46
SRR25158347_k127_349402_21	1121127.JAFA01000012_gene7390	3.911e-10	67.0	COG4384@1|root,COG4384@2|Bacteria,1MZ4H@1224|Proteobacteria,2VWYQ@28216|Betaproteobacteria,1KI7H@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacteriophage Mu Gp45 protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_Gp45
SRR25158347_k127_349402_9	1278073.MYSTI_01921	1.635e-41	166.0	COG4379@1|root,COG4379@2|Bacteria,1MX68@1224|Proteobacteria,42RQV@68525|delta/epsilon subdivisions,2WNV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_349402_14	754331.AEME01000001_gene217	2.504e-20	104.0	COG4228@1|root,COG4228@2|Bacteria,1R4HU@1224|Proteobacteria,1RPRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DNA circulation protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N
SRR25158347_k127_349402_5	938288.HG326225_gene1132	5.672e-59	230.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,269ZS@186813|unclassified Clostridiales	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,TMP
SRR25158347_k127_349402_8	1268068.PG5_42320	4.885e-42	157.0	2DP11@1|root,33031@2|Bacteria,1RH3P@1224|Proteobacteria	1224|Proteobacteria	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	Tail_tube
SRR25158347_k127_349402_1	690850.Desaf_1922	2.249e-127	423.0	COG4386@1|root,COG4386@2|Bacteria,1MXZD@1224|Proteobacteria,42YRB@68525|delta/epsilon subdivisions,2WTP7@28221|Deltaproteobacteria,2MAFC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tail sheath	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158347_k127_349402_10	198467.NP92_02830	4.243e-41	165.0	2C57E@1|root,2Z8WK@2|Bacteria,1TPTU@1239|Firmicutes,4HBUR@91061|Bacilli	91061|Bacilli	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
SRR25158347_k127_349402_18	748280.NH8B_0557	1.282e-11	70.0	2DMA4@1|root,32B9P@2|Bacteria,1MYHB@1224|Proteobacteria,2VWB5@28216|Betaproteobacteria,2KTAY@206351|Neisseriales	206351|Neisseriales	S	Bacteriophage lambda head decoration protein D	-	-	-	-	-	-	-	-	-	-	-	-	HDPD
SRR25158347_k127_349402_7	1317118.ATO8_21226	1.066e-47	186.0	COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2U2TT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OU	COG0616 periplasmic serine proteases (ClpP class)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S49
SRR25158347_k127_349402_26	158190.SpiGrapes_1233	0.0001792	48.0	COG1974@1|root,COG1974@2|Bacteria,2J7ID@203691|Spirochaetes	203691|Spirochaetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158347_k127_349402_3	742823.HMPREF9465_00223	1.015e-83	297.0	COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2VKKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage portal protein, lambda family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
SRR25158347_k127_349402_0	570417.WP0255	2.626e-172	560.0	COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,2TRW8@28211|Alphaproteobacteria,47G2T@766|Rickettsiales	766|Rickettsiales	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
SRR25158347_k127_349402_22	156889.Mmc1_2907	2.73e-09	65.0	2E7D6@1|root,331WB@2|Bacteria,1N98T@1224|Proteobacteria,2UIKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_349402_2	1196322.A370_02058	6.304e-120	391.0	COG0270@1|root,COG0270@2|Bacteria	2|Bacteria	L	DNA (cytosine-5-)-methyltransferase activity	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,Eco57I
SRR25158347_k127_349402_11	1341157.RF007C_04375	4.398e-21	100.0	28MZE@1|root,2ZB64@2|Bacteria,1VZAU@1239|Firmicutes,252WI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_349402_12	316274.Haur_0198	8.414e-21	95.0	COG2411@1|root,COG2411@2|Bacteria	2|Bacteria	-	-	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	ASCH
SRR25158347_k127_349402_4	1502724.FF80_03305	2.079e-67	239.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Gp37Gp68 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158347_k127_349402_24	502025.Hoch_2446	3.33e-08	59.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158347_k127_349402_13	1122173.AXVL01000063_gene379	2.492e-20	102.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phg_2220_C
SRR25158347_k127_349402_16	999411.HMPREF1092_00899	3.688e-13	78.0	2EFU0@1|root,339K4@2|Bacteria,1U2XC@1239|Firmicutes,24ME0@186801|Clostridia,36K2B@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_349402_23	1285586.H131_14998	5.027e-09	61.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,4HS33@91061|Bacilli,3IYVP@400634|Lysinibacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
SRR25158347_k127_349402_19	639282.DEFDS_1801	3.495e-11	74.0	COG4974@1|root,COG4974@2|Bacteria,2GEQP@200930|Deferribacteres	200930|Deferribacteres	D	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158347_k127_3496208_0	215803.DB30_5293	5.819e-68	237.0	COG0604@1|root,COG0604@2|Bacteria,1MW2V@1224|Proteobacteria,433WU@68525|delta/epsilon subdivisions,2X2BB@28221|Deltaproteobacteria,2YXH4@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_3501765_0	1313421.JHBV01000005_gene4538	5.507e-29	125.0	COG3920@1|root,COG5000@1|root,COG3920@2|Bacteria,COG5000@2|Bacteria,4NINT@976|Bacteroidetes,1IT68@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_3,PAS_9
SRR25158347_k127_3501765_1	931626.Awo_c16830	7.43e-05	53.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,25XB2@186806|Eubacteriaceae	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158347_k127_3503170_1	1033737.CAEV01000007_gene2535	2.065e-14	85.0	COG1668@1|root,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,36GGI@31979|Clostridiaceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
SRR25158347_k127_3503170_0	2325.TKV_c03990	1.88e-17	84.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia,42FE0@68295|Thermoanaerobacterales	186801|Clostridia	CP	PFAM ABC transporter related	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
SRR25158347_k127_3503980_0	997346.HMPREF9374_2509	1.167e-103	347.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,27B0A@186824|Thermoactinomycetaceae	91061|Bacilli	D	GidA associated domain 3	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158347_k127_3503980_3	1192124.LIG30_1991	9.775e-43	164.0	COG2227@1|root,COG2227@2|Bacteria,1QVYA@1224|Proteobacteria,2WGUM@28216|Betaproteobacteria,1KG4P@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_3503980_2	889378.Spiaf_1842	8.878e-69	244.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	fprA1	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158347_k127_3503980_1	1313301.AUGC01000003_gene1911	5.224e-102	345.0	COG4399@1|root,COG4399@2|Bacteria,4NIDM@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3504401_1	1396141.BATP01000003_gene5282	3.253e-09	59.0	COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,2ITV2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158347_k127_3504401_0	1232410.KI421413_gene720	7.044e-98	325.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,43TZZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
SRR25158347_k127_3505272_0	1123234.AUKI01000015_gene2340	3.64e-119	392.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,1HZQ0@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_3505272_1	1123234.AUKI01000015_gene2338	1.312e-32	130.0	COG0438@1|root,COG0438@2|Bacteria,4NE53@976|Bacteroidetes,1HX83@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158347_k127_3506277_1	111780.Sta7437_4112	2.641e-34	154.0	COG4932@1|root,COG4932@2|Bacteria,1GIGP@1117|Cyanobacteria,3VKF3@52604|Pleurocapsales	1117|Cyanobacteria	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
SRR25158347_k127_3506277_0	1408473.JHXO01000015_gene1925	5.381e-156	539.0	COG2247@1|root,COG2911@1|root,COG4733@1|root,COG2247@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,4PHY6@976|Bacteroidetes,2FTM3@200643|Bacteroidia	976|Bacteroidetes	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3508241_0	391595.RLO149_c001270	3.532e-109	359.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2P1Y2@2433|Roseobacter	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158347_k127_3508241_1	1173026.Glo7428_3186	2.02e-28	119.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158347_k127_3511012_3	671143.DAMO_2068	4.089e-12	73.0	COG2050@1|root,COG2050@2|Bacteria,2NQ0Q@2323|unclassified Bacteria	2|Bacteria	Q	Thioesterase superfamily	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
SRR25158347_k127_3511012_1	1184267.A11Q_2136	1.728e-38	160.0	COG1538@1|root,COG1538@2|Bacteria,1Q54S@1224|Proteobacteria,42W8E@68525|delta/epsilon subdivisions,2MTWA@213481|Bdellovibrionales,2WSDF@28221|Deltaproteobacteria	213481|Bdellovibrionales	MU	FusA NodT family protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158347_k127_3511012_0	194439.CT0377	5.103e-70	249.0	COG0845@1|root,COG0845@2|Bacteria,1FDM9@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158347_k127_3511012_2	194439.CT0378	3.361e-31	124.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1FDCY@1090|Chlorobi	1090|Chlorobi	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
SRR25158347_k127_3512793_0	388413.ALPR1_06560	1.486e-93	311.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47QIE@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_3515400_0	331113.SNE_A13280	2.175e-132	437.0	COG0591@1|root,COG0591@2|Bacteria,2JHDG@204428|Chlamydiae	204428|Chlamydiae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158347_k127_3515640_0	1480694.DC28_10265	1.195e-25	108.0	2C3HB@1|root,333QE@2|Bacteria,2J8P5@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3515640_1	1499498.EV05_0154	3.795e-22	101.0	COG0132@1|root,COG0132@2|Bacteria,1G03P@1117|Cyanobacteria,1MMBG@1212|Prochloraceae	1117|Cyanobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR25158347_k127_3516632_1	148304.MAPG_09811T0	7.408e-08	57.0	COG4870@1|root,KOG1543@2759|Eukaryota	2759|Eukaryota	O	cysteine-type peptidase activity	-	-	3.4.22.15,3.4.22.16	ko:K01365,ko:K01366,ko:K11446	ko04140,ko04142,ko04145,ko04210,ko04612,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00537,ko01000,ko01002,ko01009,ko03036,ko03110	-	-	-	Kringle,Peptidase_C1
SRR25158347_k127_3516632_0	56110.Oscil6304_5477	8.917e-12	74.0	2EPY9@1|root,33HIV@2|Bacteria,1G8GC@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3517559_0	269798.CHU_3403	1.015e-15	78.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47K7U@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
SRR25158347_k127_3518270_1	1267534.KB906755_gene4552	5.665e-07	55.0	COG1131@1|root,COG1131@2|Bacteria,3Y4F1@57723|Acidobacteria,2JJ6F@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158347_k127_3518270_0	981383.AEWH01000012_gene3869	6.825e-22	100.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158347_k127_3526389_1	195103.CPF_0092	1.254e-05	55.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36EV3@31979|Clostridiaceae	186801|Clostridia	I	acyl-CoA dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158347_k127_3526389_0	706587.Desti_2066	3.755e-15	78.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3528275_0	767817.Desgi_4028	3.27e-57	212.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158347_k127_3528734_0	986075.CathTA2_1897	8.222e-64	229.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
SRR25158347_k127_3528734_1	313606.M23134_01400	3.539e-27	113.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
SRR25158347_k127_3528737_0	498761.HM1_1507	3.713e-58	218.0	COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,248BK@186801|Clostridia	186801|Clostridia	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,YkuI_C
SRR25158347_k127_3535869_0	1122951.ATUE01000005_gene1917	1.306e-149	484.0	28MTI@1|root,2ZB1Q@2|Bacteria,1R894@1224|Proteobacteria,1SMF1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3535869_1	1122951.ATUE01000005_gene1918	8.909e-64	226.0	2E3NC@1|root,32YKG@2|Bacteria,1NRC9@1224|Proteobacteria,1SK29@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3538583_2	1121481.AUAS01000006_gene877	3.356e-26	126.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
SRR25158347_k127_3538583_0	497965.Cyan7822_0442	1.647e-50	191.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158347_k127_3538583_1	404589.Anae109_0475	7.918e-49	188.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
SRR25158347_k127_3538583_3	1201290.M902_2905	8.193e-14	71.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,43731@68525|delta/epsilon subdivisions,2MTR5@213481|Bdellovibrionales,2WKPB@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158347_k127_3538835_0	868864.Dester_0804	6.916e-37	143.0	COG0859@1|root,COG0859@2|Bacteria,2G3MK@200783|Aquificae	200783|Aquificae	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158347_k127_3538835_1	1121904.ARBP01000002_gene7250	4.114e-17	93.0	COG0664@1|root,COG3202@1|root,COG0664@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,47JM4@768503|Cytophagia	976|Bacteroidetes	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
SRR25158347_k127_3540344_0	1122603.ATVI01000006_gene527	8.148e-86	287.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,1RZ9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3540344_1	1122603.ATVI01000006_gene528	1.152e-69	241.0	28MTI@1|root,2ZB1Q@2|Bacteria,1R894@1224|Proteobacteria,1SMF1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3540501_0	1121374.KB891588_gene3307	2.535e-71	249.0	COG3239@1|root,COG3239@2|Bacteria,1MXTQ@1224|Proteobacteria,1RRM8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158347_k127_3540501_1	582402.Hbal_1667	5.742e-06	55.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,43YBH@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	COG2867 Oligoketide cyclase lipid transport protein	pasT	-	-	ko:K18588	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
SRR25158347_k127_3542058_0	273068.TTE0038	0.0002245	53.0	COG2203@1|root,COG2206@1|root,COG3850@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3850@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42GDE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HAMP,HD,HD_5,PAS_9,PocR,Response_reg
SRR25158347_k127_3545099_1	1047013.AQSP01000142_gene165	1.135e-77	273.0	COG3591@1|root,COG3591@2|Bacteria,2NQEJ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158347_k127_3545099_0	395493.BegalDRAFT_1341	3.244e-99	333.0	COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,1RNSV@1236|Gammaproteobacteria,46085@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158347_k127_3545099_2	179408.Osc7112_6240	1.057e-23	116.0	COG2114@1|root,COG2202@1|root,COG3437@1|root,COG2114@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,1GQRR@1117|Cyanobacteria,1H9GQ@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,PAS_9,Response_reg
SRR25158347_k127_3546328_2	1336803.PHEL49_2027	0.0009976	49.0	2A0YP@1|root,30P3X@2|Bacteria,4NNZJ@976|Bacteroidetes,1I23I@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158347_k127_3546328_1	391625.PPSIR1_36357	6.473e-18	91.0	COG1309@1|root,COG1309@2|Bacteria,1PFNS@1224|Proteobacteria,438SJ@68525|delta/epsilon subdivisions,2WY8E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158347_k127_3546328_0	1408254.T458_02875	1.485e-66	242.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,26T7K@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158347_k127_3546843_0	313606.M23134_04414	1.998e-121	407.0	COG0515@1|root,COG2203@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,4PM99@976|Bacteroidetes,47KKS@768503|Cytophagia	976|Bacteroidetes	KLT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,Pkinase,SpoIIE
SRR25158347_k127_3548433_0	1134474.O59_001771	1.525e-63	232.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1FG4H@10|Cellvibrio	1236|Gammaproteobacteria	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158347_k127_3552205_1	1122216.AUHW01000005_gene442	1.941e-24	106.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H2Y8@909932|Negativicutes	909932|Negativicutes	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158347_k127_3552205_0	59374.Fisuc_2644	2.184e-129	421.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	leuB	GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082	Iso_dh
SRR25158347_k127_3555792_0	762903.Pedsa_1120	6.063e-116	383.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1IP49@117747|Sphingobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158347_k127_3555792_1	1121904.ARBP01000001_gene5390	1.029e-78	267.0	COG1335@1|root,COG1335@2|Bacteria,4NKPP@976|Bacteroidetes,47PIR@768503|Cytophagia	976|Bacteroidetes	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158347_k127_3555792_2	56780.SYN_02636	1.119e-61	220.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158347_k127_3555792_3	1460635.JCM19038_3591	4.333e-33	135.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli	91061|Bacilli	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158347_k127_3556141_1	400682.PAC_15727700	4.278e-41	162.0	COG5018@1|root,KOG0542@2759|Eukaryota,39RFZ@33154|Opisthokonta,3BBKW@33208|Metazoa	33208|Metazoa	L	exonuclease activity	ERI3	GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K18418	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	RNase_T
SRR25158347_k127_3556141_0	502025.Hoch_6745	3.892e-43	162.0	2DJ5J@1|root,32UCF@2|Bacteria,1N1M7@1224|Proteobacteria,430W5@68525|delta/epsilon subdivisions,2WW0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3556141_2	1202532.FF52_09848	4.538e-20	95.0	COG2207@1|root,COG2207@2|Bacteria,4NIRD@976|Bacteroidetes,1I0T7@117743|Flavobacteriia,2NVA7@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158347_k127_3557071_0	321332.CYB_2880	5.656e-125	408.0	COG0312@1|root,COG0312@2|Bacteria,1G0BB@1117|Cyanobacteria,1GYUI@1129|Synechococcus	1117|Cyanobacteria	S	Putative modulator of DNA gyrase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158347_k127_3559836_0	1173026.Glo7428_1413	7.287e-32	135.0	COG0615@1|root,COG0615@2|Bacteria,1G3Z9@1117|Cyanobacteria	1117|Cyanobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158347_k127_356064_0	794903.OPIT5_18080	7.366e-20	93.0	COG4285@1|root,COG4285@2|Bacteria,46V2C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Biotin-protein ligase, N terminal	-	-	-	-	-	-	-	-	-	-	-	-	BPL_N
SRR25158347_k127_3562830_3	1041930.Mtc_1597	2.753e-21	95.0	COG2021@1|root,arCOG00627@2157|Archaea,2XTYY@28890|Euryarchaeota,2N9C1@224756|Methanomicrobia	224756|Methanomicrobia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,CBS
SRR25158347_k127_3562830_1	56780.SYN_01259	7.907e-55	199.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,42QRQ@68525|delta/epsilon subdivisions,2WMRU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	TIGRFAM methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
SRR25158347_k127_3562830_0	1499967.BAYZ01000029_gene1216	2.17e-75	265.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158347_k127_3562830_2	556263.FSEG_01476	1.482e-46	173.0	COG0615@1|root,COG0615@2|Bacteria,37A0X@32066|Fusobacteria	32066|Fusobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE2	-	2.7.7.39	ko:K00980	ko00564,map00564	-	R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
SRR25158347_k127_3562830_4	1410609.JHVB01000003_gene314	0.0008813	49.0	293BT@1|root,302R7@2|Bacteria,2J86K@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3563389_0	886377.Murru_2896	1.24e-76	268.0	COG0477@1|root,COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0477@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
SRR25158347_k127_356356_3	1123400.KB904754_gene973	3.43e-28	119.0	COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,1S9JV@1236|Gammaproteobacteria,4631Y@72273|Thiotrichales	72273|Thiotrichales	T	Cyclin-dependent kinase inhibitor 3 (CDKN3)	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
SRR25158347_k127_356356_2	945713.IALB_2903	7.026e-34	136.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158347_k127_356356_5	1392489.JPOL01000002_gene975	4.667e-16	81.0	COG2442@1|root,COG2442@2|Bacteria,4NV5I@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158347_k127_356356_4	1454007.JAUG01000058_gene3490	1.382e-26	111.0	COG4634@1|root,COG4634@2|Bacteria,4NVD2@976|Bacteroidetes,1IYC5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_356356_0	1380350.JIAP01000023_gene3703	6.663e-164	528.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158347_k127_356356_1	1173028.ANKO01000017_gene82	3.144e-64	235.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_3567758_0	1192034.CAP_4421	1.525e-62	225.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2YTU2@29|Myxococcales	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_3567758_1	1150600.ADIARSV_0851	5.849e-48	178.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158347_k127_3568461_1	1408444.JHYC01000004_gene692	8.726e-06	53.0	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,1SNAF@1236|Gammaproteobacteria,1JE2M@118969|Legionellales	118969|Legionellales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3568461_0	1301100.HG529420_gene2930	1.318e-22	106.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,36IPK@31979|Clostridiaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
SRR25158347_k127_3573108_0	118168.MC7420_3521	3.076e-46	181.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,HATPase_c,HisKA,Pkinase
SRR25158347_k127_3573195_0	929562.Emtol_2637	9.029e-62	218.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,47JKE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_3573708_1	1289135.A966_10367	1.779e-19	94.0	COG5009@1|root,COG5009@2|Bacteria,2J5D4@203691|Spirochaetes	203691|Spirochaetes	M	penicillin-binding protein	pbp-3	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_3573708_0	1047013.AQSP01000123_gene1540	1.206e-35	147.0	COG0177@1|root,COG0177@2|Bacteria,2NQYE@2323|unclassified Bacteria	2|Bacteria	L	Protein of unknown function (DUF2400)	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF2400,EndIII_4Fe-2S,HhH-GPD
SRR25158347_k127_3576856_0	1158294.JOMI01000004_gene3352	2.701e-257	805.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,2FMTG@200643|Bacteroidia	976|Bacteroidetes	G	1,4-alpha-glucan branching enzyme	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158347_k127_3581275_0	1173027.Mic7113_0758	6.635e-95	320.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_3583129_0	445961.IW15_16190	2.242e-190	624.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,3ZQGU@59732|Chryseobacterium	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
SRR25158347_k127_3583554_0	1151117.AJLF01000001_gene1492	3.72e-14	86.0	arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
SRR25158347_k127_3583554_1	1500894.JQNN01000001_gene285	9.187e-12	75.0	28IB9@1|root,2Z8DS@2|Bacteria,1MXCT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_358736_0	1191523.MROS_2574	4.816e-136	446.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158347_k127_3588858_1	865937.Gilli_0455	5.433e-25	104.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1HXRU@117743|Flavobacteriia,2P6HI@244698|Gillisia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_3588858_0	865937.Gilli_0456	3.394e-110	359.0	28N47@1|root,2ZB9Q@2|Bacteria,4NMNP@976|Bacteroidetes,1I1SS@117743|Flavobacteriia,2P6Z7@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_358937_0	1189620.AJXL01000042_gene599	3.191e-48	186.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia,2NSQ1@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
SRR25158347_k127_3591798_0	1304284.L21TH_2485	1.396e-28	124.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,36HPG@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158347_k127_3596615_0	1121405.dsmv_0045	2.523e-31	127.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PZJ@68525|delta/epsilon subdivisions,2WMGB@28221|Deltaproteobacteria,2MNPX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158347_k127_3596615_1	118168.MC7420_6094	4.44e-08	64.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1GCNC@1117|Cyanobacteria,1HF54@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158347_k127_3600052_0	880071.Fleli_1626	1.402e-24	115.0	COG1075@1|root,COG1075@2|Bacteria,4NR4R@976|Bacteroidetes,47UZJ@768503|Cytophagia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
SRR25158347_k127_360679_1	1379698.RBG1_1C00001G0287	7.753e-10	71.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
SRR25158347_k127_360679_0	498761.HM1_2362	1.515e-24	118.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158347_k127_3606940_1	546275.FUSPEROL_01568	1.21e-25	109.0	COG0028@1|root,COG0028@2|Bacteria,378RW@32066|Fusobacteria	32066|Fusobacteria	H	acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158347_k127_3606940_0	1499967.BAYZ01000122_gene3366	1.103e-43	165.0	COG0440@1|root,COG0440@2|Bacteria,2NPPK@2323|unclassified Bacteria	2|Bacteria	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
SRR25158347_k127_3607034_0	1173028.ANKO01000017_gene82	2.207e-71	246.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
SRR25158347_k127_3607768_0	1125725.HMPREF1325_2561	3.248e-07	60.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3612052_0	1121935.AQXX01000039_gene3862	1.643e-25	109.0	COG3209@1|root,COG3209@2|Bacteria,1N4HV@1224|Proteobacteria,1SAZM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	cellulase activity	-	-	-	ko:K11021	-	-	-	-	ko00000,ko02042	-	-	-	RHS
SRR25158347_k127_3612052_1	313590.MED134_06959	4.603e-18	93.0	2CJFU@1|root,2Z8SP@2|Bacteria,4NI05@976|Bacteroidetes,1I2TI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3615093_2	547144.HydHO_0445	1.578e-09	58.0	COG1672@1|root,COG1672@2|Bacteria,2G4U4@200783|Aquificae	200783|Aquificae	S	Conserved protein, with A weak D-galactarate dehydratase altronate hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
SRR25158347_k127_3615093_1	386456.JQKN01000013_gene2966	1.162e-37	154.0	COG0642@1|root,COG3920@1|root,arCOG02335@2157|Archaea,arCOG02358@2157|Archaea,arCOG06192@2157|Archaea,2Y2CM@28890|Euryarchaeota	28890|Euryarchaeota	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_3
SRR25158347_k127_3615093_0	984262.SGRA_1904	2.087e-118	387.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158347_k127_3615193_1	489825.LYNGBM3L_63840	4.761e-24	109.0	COG4320@1|root,COG4320@2|Bacteria,1G2CN@1117|Cyanobacteria,1H7R5@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158347_k127_3615193_0	880071.Fleli_2050	8.649e-166	532.0	COG1488@1|root,COG1488@2|Bacteria,4NFQK@976|Bacteroidetes,47MZ6@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158347_k127_3618919_0	688269.Theth_1368	6.93e-116	384.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803,ko:K11472	ko00565,ko00630,ko01100,ko01110,ko01120,ko01130,ko04146,map00565,map00630,map01100,map01110,map01120,map01130,map04146	-	R00475,R04311	RC00020,RC00042,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158347_k127_3620183_0	1944.JOAZ01000001_gene4155	1.095e-104	347.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,418JH@629295|Streptomyces griseus group	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_362297_0	1121422.AUMW01000009_gene3291	4.082e-92	313.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,267C6@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158347_k127_3623796_0	756067.MicvaDRAFT_3583	1.99e-138	458.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
SRR25158347_k127_3624862_0	1282361.ABAC402_19250	2.011e-08	66.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2TUJ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	MA20_09270	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
SRR25158347_k127_3625831_1	1197477.IA57_04750	5.741e-105	347.0	COG3440@1|root,COG3440@2|Bacteria,4NFST@976|Bacteroidetes,1I11R@117743|Flavobacteriia	976|Bacteroidetes	L	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
SRR25158347_k127_3625831_0	1250278.JQNQ01000001_gene109	1.35e-124	407.0	arCOG03518@1|root,32RB1@2|Bacteria,4NQUK@976|Bacteroidetes,1I337@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3625831_2	1347342.BN863_18800	4.809e-31	122.0	COG1474@1|root,COG1974@1|root,COG3410@1|root,COG1474@2|Bacteria,COG1974@2|Bacteria,COG3410@2|Bacteria,4NHW6@976|Bacteroidetes,1HZCV@117743|Flavobacteriia	976|Bacteroidetes	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075,GIY-YIG
SRR25158347_k127_3629186_0	411154.GFO_1056	2.63e-96	317.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1I18Y@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_3629186_1	411154.GFO_1055	7.261e-33	131.0	2E7DN@1|root,331WR@2|Bacteria,4NVC6@976|Bacteroidetes,1I5FN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3632350_1	1080067.BAZH01000008_gene48	0.0004258	52.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,3WX4F@544|Citrobacter	1236|Gammaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
SRR25158347_k127_3632350_0	880071.Fleli_2790	5.549e-37	145.0	COG1409@1|root,COG1409@2|Bacteria,4P3GR@976|Bacteroidetes	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158347_k127_3636302_0	198467.NP92_02815	1.782e-67	244.0	COG5511@1|root,COG5511@2|Bacteria,1TQ8B@1239|Firmicutes,4HCQE@91061|Bacilli	91061|Bacilli	S	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
SRR25158347_k127_3636618_1	935837.JAEK01000020_gene623	1.587e-05	49.0	COG0537@1|root,COG0537@2|Bacteria,1V5Q0@1239|Firmicutes,4HHB2@91061|Bacilli,1ZGHY@1386|Bacillus	91061|Bacilli	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158347_k127_3636618_0	1196029.ALIM01000014_gene2636	3.557e-74	258.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	sftA	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Ftsk_gamma
SRR25158347_k127_3639817_1	1117314.PCIT_03863	4.751e-07	54.0	COG0642@1|root,COG2205@2|Bacteria,1PDVQ@1224|Proteobacteria,1RQEH@1236|Gammaproteobacteria,2Q19Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	sensory histidine kinase in two-component regulatory system	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_3639817_0	1121448.DGI_3242	1.703e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,42SAC@68525|delta/epsilon subdivisions,2WP7J@28221|Deltaproteobacteria,2MBHN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	cheY34H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158347_k127_3644309_0	1120936.KB907212_gene5262	4.031e-109	359.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria	201174|Actinobacteria	I	fatty acid desaturase	desA3	GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158347_k127_3644937_0	714943.Mucpa_5306	6.206e-46	169.0	COG1487@1|root,COG1487@2|Bacteria,4NSBY@976|Bacteroidetes,1IYU6@117747|Sphingobacteriia	976|Bacteroidetes	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158347_k127_3644937_1	945713.IALB_2903	3.941e-33	133.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158347_k127_3646433_1	1123368.AUIS01000001_gene2115	4.332e-06	56.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,2NCJX@225057|Acidithiobacillales	225057|Acidithiobacillales	N	FliG middle domain	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_N
SRR25158347_k127_3646433_0	1123274.KB899413_gene855	7.234e-97	337.0	COG1766@1|root,COG1766@2|Bacteria,2J5KB@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar M-ring protein	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
SRR25158347_k127_3647686_0	1190603.AJYD01000015_gene959	5.769e-76	267.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XWMA@135623|Vibrionales	135623|Vibrionales	T	PAS fold	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4
SRR25158347_k127_3647686_2	1538295.JY96_12250	2.803e-09	59.0	COG0642@1|root,COG3300@1|root,COG2205@2|Bacteria,COG3300@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KMW2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_3647686_1	1288494.EBAPG3_11750	9.168e-10	66.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE,KAP_NTPase,PG_binding_1,WD40
SRR25158347_k127_3652653_1	313606.M23134_06670	1.767e-37	143.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
SRR25158347_k127_3652653_0	43989.cce_1086	1.346e-58	221.0	COG3344@1|root,COG3344@2|Bacteria,1G1DZ@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
SRR25158347_k127_3660038_0	639282.DEFDS_0061	1.381e-87	301.0	COG0182@1|root,COG0182@2|Bacteria,2GEMI@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158347_k127_3660038_1	1123326.JFBL01000018_gene2378	5.607e-25	106.0	COG3205@1|root,COG3205@2|Bacteria,1NA8W@1224|Proteobacteria,42W08@68525|delta/epsilon subdivisions,2YQND@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
SRR25158347_k127_3661017_0	1173022.Cri9333_0218	1.348e-168	555.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_3662422_0	1450525.JATV01000006_gene1044	5.718e-18	89.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia,2NX3W@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
SRR25158347_k127_3662797_0	388467.A19Y_2493	1.513e-138	444.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158347_k127_3662797_1	391625.PPSIR1_07593	9.661e-26	114.0	COG0515@1|root,COG0515@2|Bacteria,1P2EB@1224|Proteobacteria,438NX@68525|delta/epsilon subdivisions,2X8TD@28221|Deltaproteobacteria,2YXD6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158347_k127_3662888_0	216432.CA2559_11723	0.0	1127.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158347_k127_3668211_0	411154.GFO_2365	8.021e-137	436.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
SRR25158347_k127_3668211_1	411154.GFO_2366	1.061e-116	377.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HWXA@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
SRR25158347_k127_3669930_0	1122971.BAME01000002_gene349	9.481e-06	58.0	COG0515@1|root,COG3209@1|root,COG0515@2|Bacteria,COG3209@2|Bacteria,4NMTE@976|Bacteroidetes,2FS85@200643|Bacteroidia,22Z0F@171551|Porphyromonadaceae	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158347_k127_3670268_0	216595.PFLU_5092	7.144e-74	263.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YRGB@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
SRR25158347_k127_3670424_2	665571.STHERM_c07640	1.822e-19	91.0	COG1699@1|root,COG1699@2|Bacteria,2J7ZU@203691|Spirochaetes	203691|Spirochaetes	N	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
SRR25158347_k127_3670424_3	588581.Cpap_2170	7.227e-19	89.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia	186801|Clostridia	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
SRR25158347_k127_3670424_1	555088.DealDRAFT_3156	1.443e-29	131.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158347_k127_3670424_0	56780.SYN_00180	1.546e-58	210.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2WXBI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_3673666_0	395493.BegalDRAFT_1073	1.847e-12	69.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4609X@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HATPase_c,HisKA,Response_reg
SRR25158347_k127_367488_0	1121422.AUMW01000005_gene633	2.299e-102	346.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158347_k127_367488_1	313628.LNTAR_13807	5.321e-35	136.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SRR25158347_k127_367488_3	1168065.DOK_18960	1.946e-06	60.0	29NXS@1|root,309VX@2|Bacteria,1QT31@1224|Proteobacteria,1ST8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_367488_2	380358.XALC_3097	2.398e-17	86.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1X3GG@135614|Xanthomonadales	135614|Xanthomonadales	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158347_k127_3676182_0	877415.JNJQ01000042_gene2676	2.741e-14	79.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,1TQY5@1239|Firmicutes	1239|Firmicutes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,SpoIIE,dCache_1
SRR25158347_k127_3676581_2	1410618.JNKI01000015_gene1559	6.64e-33	128.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158347_k127_3676581_0	498211.CJA_1964	1.517e-102	340.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1FGUU@10|Cellvibrio	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158347_k127_3676581_1	720554.Clocl_3980	4.894e-48	177.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158347_k127_3685637_0	1173263.Syn7502_03042	1.129e-09	63.0	COG4636@1|root,COG4636@2|Bacteria,1G5HH@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158347_k127_3690162_0	313628.LNTAR_02372	2.993e-45	169.0	COG0502@1|root,COG0502@2|Bacteria	2|Bacteria	H	biotin synthase activity	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU30200	BATS,Radical_SAM
SRR25158347_k127_3690186_0	1173027.Mic7113_1528	7.434e-10	72.0	COG5316@1|root,COG5316@2|Bacteria,1GCFS@1117|Cyanobacteria,1HECU@1150|Oscillatoriales	1117|Cyanobacteria	NU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SRR25158347_k127_3690186_1	7739.XP_002612639.1	8.074e-07	57.0	28Q1A@1|root,2QWQ0@2759|Eukaryota,39YYB@33154|Opisthokonta,3BJDT@33208|Metazoa,3D721@33213|Bilateria	33208|Metazoa	S	N-terminal domain of unknown function (DUF4140)	-	GO:0003674,GO:0005488,GO:0005515	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
SRR25158347_k127_3691269_0	1449338.JQLU01000003_gene560	1.259e-88	303.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,27FV0@186828|Carnobacteriaceae	91061|Bacilli	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR25158347_k127_3692105_1	313606.M23134_05297	1.896e-112	374.0	COG0204@1|root,COG0204@2|Bacteria,4NJDA@976|Bacteroidetes,47MU0@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3692105_0	1122951.ATUE01000005_gene1916	0.0	1035.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,1RZ9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3694583_1	1131269.AQVV01000004_gene596	2.913e-27	123.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158347_k127_3694583_0	10224.XP_006813521.1	3.48e-44	174.0	COG0429@1|root,KOG1838@2759|Eukaryota,393GS@33154|Opisthokonta,3BF3B@33208|Metazoa,3CW8G@33213|Bilateria	33208|Metazoa	S	cellular lipid metabolic process	ABHD15	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704	-	ko:K13707	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158347_k127_3701883_1	1268239.PALB_13410	1.596e-07	65.0	COG5276@1|root,COG5276@2|Bacteria,1QW1C@1224|Proteobacteria,1S0U6@1236|Gammaproteobacteria,2Q0TX@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
SRR25158347_k127_3701883_0	400682.PAC_15706993	2.504e-15	91.0	29RY4@1|root,2RXCD@2759|Eukaryota,3AHIP@33154|Opisthokonta,3BZGS@33208|Metazoa	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	REJ,Tetraspannin
SRR25158347_k127_3710414_1	395494.Galf_2528	5.115e-30	123.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WCD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Phosphonate-bd
SRR25158347_k127_3710414_0	909663.KI867150_gene2380	2.027e-67	241.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SRR25158347_k127_3711221_1	481448.Minf_0537	4.095e-09	65.0	COG0791@1|root,COG0791@2|Bacteria,46SVG@74201|Verrucomicrobia,37GHP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	NlpC/P60 family	spr	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158347_k127_3711221_0	497964.CfE428DRAFT_5336	2.744e-70	243.0	COG2230@1|root,COG2230@2|Bacteria,46TH2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158347_k127_3714082_0	290512.Paes_1402	1.951e-96	338.0	COG0841@1|root,COG0841@2|Bacteria,1FEYE@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_3714354_0	203119.Cthe_1312	6.398e-146	471.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158347_k127_3714625_0	1408813.AYMG01000007_gene4335	2.836e-58	205.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158347_k127_3714625_1	1121859.KB890754_gene798	1.888e-25	120.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
SRR25158347_k127_3714625_2	1248232.BANQ01000150_gene4019	9.815e-08	62.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XVCX@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_19,TPR_2,VWA_2
SRR25158347_k127_3720091_1	1340434.AXVA01000007_gene4969	5.315e-10	70.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZEFV@1386|Bacillus	91061|Bacilli	O	Subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158347_k127_3720091_0	665571.STHERM_c08540	4.165e-67	237.0	COG1022@1|root,COG1022@2|Bacteria,2J59B@203691|Spirochaetes	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_3726047_1	1121943.KB900012_gene4060	8.859e-72	250.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,1XRIQ@135619|Oceanospirillales	135619|Oceanospirillales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
SRR25158347_k127_3726047_2	522772.Dacet_0624	1.479e-26	110.0	COG2963@1|root,COG2963@2|Bacteria,2GGNA@200930|Deferribacteres	200930|Deferribacteres	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158347_k127_3726047_0	1278307.KB907020_gene881	4.245e-78	271.0	COG0834@1|root,COG0834@2|Bacteria,1RD01@1224|Proteobacteria,1S43D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRR25158347_k127_3727001_0	431943.CKL_2386	8.306e-06	57.0	COG0845@1|root,COG0845@2|Bacteria,1V3TH@1239|Firmicutes,24AAF@186801|Clostridia,36FC9@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158347_k127_3727740_0	1293054.HSACCH_02649	2.293e-43	166.0	COG0420@1|root,COG0420@2|Bacteria,1V3MP@1239|Firmicutes,24J4M@186801|Clostridia	186801|Clostridia	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158347_k127_3727740_1	1313301.AUGC01000008_gene404	3.896e-27	117.0	COG2318@1|root,COG2318@2|Bacteria,4NSP0@976|Bacteroidetes	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
SRR25158347_k127_3728060_0	416591.Tlet_1443	2.613e-70	261.0	COG3345@1|root,COG3345@2|Bacteria,2GC20@200918|Thermotogae	200918|Thermotogae	G	Melibiase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
SRR25158347_k127_3728060_1	1218108.KB908296_gene3263	1.244e-26	119.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1HZB4@117743|Flavobacteriia	976|Bacteroidetes	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158347_k127_3734120_2	1217705.F900_00369	0.000666	50.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,3NK73@468|Moraxellaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
SRR25158347_k127_3734120_0	1234593.ANBY01000039_gene1561	4.144e-13	78.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,4HKQJ@91061|Bacilli,4GY86@90964|Staphylococcaceae	91061|Bacilli	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
SRR25158347_k127_3734120_1	1296416.JACB01000005_gene203	5.69e-06	59.0	COG4757@1|root,COG4757@2|Bacteria,4NJ3M@976|Bacteroidetes,1HYBK@117743|Flavobacteriia,2YIQI@290174|Aquimarina	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158347_k127_3734458_0	933262.AXAM01000030_gene798	1.246e-111	372.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria,2MPTC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158347_k127_3735937_0	1184267.A11Q_280	1.211e-117	386.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2MSPI@213481|Bdellovibrionales,2WK2U@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_3735937_1	1132442.KB889752_gene3855	2.254e-75	261.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158347_k127_3736456_0	332101.JIBU02000004_gene111	4.297e-06	57.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,36FFV@31979|Clostridiaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158347_k127_3737824_1	313606.M23134_02127	1.627e-23	106.0	COG1881@1|root,COG1881@2|Bacteria,4NGHZ@976|Bacteroidetes,47KC4@768503|Cytophagia	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
SRR25158347_k127_3737824_2	1296415.JACC01000003_gene3141	1.319e-14	81.0	COG2849@1|root,COG2849@2|Bacteria,4NSKP@976|Bacteroidetes,1I4QB@117743|Flavobacteriia,2YJXT@290174|Aquimarina	976|Bacteroidetes	S	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
SRR25158347_k127_3737824_0	745718.JADT01000001_gene2075	6.644e-34	139.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HY5J@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158347_k127_374459_0	1499967.BAYZ01000089_gene5053	1.93e-162	520.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158347_k127_3745895_0	1239962.C943_02054	1.039e-54	198.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47KIN@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158347_k127_3745949_1	926549.KI421517_gene2173	5.805e-34	134.0	COG1451@1|root,COG1451@2|Bacteria,4NNY6@976|Bacteroidetes,47QZY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158347_k127_3745949_0	1280696.ATVY01000001_gene3548	1.016e-36	147.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,4BWHC@830|Butyrivibrio	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158347_k127_3747436_0	375286.mma_0216	2.24e-06	58.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VR04@28216|Betaproteobacteria,4732V@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SRR25158347_k127_3752524_0	1125863.JAFN01000001_gene796	7.114e-38	159.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3752524_1	643867.Ftrac_1680	2.881e-29	124.0	COG0501@1|root,COG0501@2|Bacteria,4PKCB@976|Bacteroidetes,47XGR@768503|Cytophagia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158347_k127_3753513_2	205918.Psyr_1674	3.637e-11	69.0	COG0388@1|root,COG0388@2|Bacteria,1RIJ5@1224|Proteobacteria,1SNS9@1236|Gammaproteobacteria,1Z4ZR@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158347_k127_3753513_3	268407.PWYN_07840	7.818e-05	50.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,4HIP6@91061|Bacilli,26YBZ@186822|Paenibacillaceae	91061|Bacilli	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158347_k127_3753513_1	404589.Anae109_1000	2.524e-16	87.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2Z1ZP@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
SRR25158347_k127_3753513_0	153721.MYP_139	4.83e-22	103.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158347_k127_3755779_0	292563.Cyast_2679	2.518e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1G3E6@1117|Cyanobacteria	1117|Cyanobacteria	L	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158347_k127_3756961_0	1089552.KI911559_gene1455	3.462e-79	273.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2JR7P@204441|Rhodospirillales	204441|Rhodospirillales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158347_k127_3756961_3	1415779.JOMH01000001_gene1097	3.379e-28	122.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SEZZ@1236|Gammaproteobacteria,1X8K6@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF374)	-	-	-	-	-	-	-	-	-	-	-	-	DUF374
SRR25158347_k127_3756961_2	330214.NIDE2543	5.811e-73	257.0	COG0616@1|root,COG0616@2|Bacteria,3J13W@40117|Nitrospirae	40117|Nitrospirae	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158347_k127_3756961_1	153721.MYP_1207	4.993e-79	280.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KQS@768503|Cytophagia	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_3757010_0	342113.DM82_3253	1.226e-120	396.0	COG0210@1|root,COG0210@2|Bacteria,1MWW6@1224|Proteobacteria,2VM7D@28216|Betaproteobacteria,1K67M@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,NERD,UvrD-helicase,UvrD_C,UvrD_C_2
SRR25158347_k127_3757010_1	1123392.AQWL01000001_gene1676	8.221e-38	143.0	COG0210@1|root,COG0210@2|Bacteria,1MWW6@1224|Proteobacteria,2VM7D@28216|Betaproteobacteria,1KTI1@119069|Hydrogenophilales	119069|Hydrogenophilales	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD_C
SRR25158347_k127_3759638_4	768706.Desor_4388	0.0001958	47.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,264T1@186807|Peptococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
SRR25158347_k127_3759638_2	1047013.AQSP01000112_gene382	3.179e-16	89.0	COG0123@1|root,COG0123@2|Bacteria,2NRDM@2323|unclassified Bacteria	2|Bacteria	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158347_k127_3759638_1	204669.Acid345_3902	1.07e-64	232.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria,2JMK7@204432|Acidobacteriia	204432|Acidobacteriia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158347_k127_3759638_0	153721.MYP_205	1.412e-78	266.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,47PI0@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158347_k127_3759638_3	449447.MAE_60910	4.342e-09	63.0	COG1672@1|root,COG1672@2|Bacteria,1G3JV@1117|Cyanobacteria	1117|Cyanobacteria	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3763398_0	1379698.RBG1_1C00001G1850	5.893e-38	153.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158347_k127_3763398_1	744872.Spica_1397	6.093e-29	123.0	COG1235@1|root,COG1235@2|Bacteria,2J5C5@203691|Spirochaetes	203691|Spirochaetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_3765920_3	1034807.FBFL15_0768	6.676e-24	104.0	COG0110@1|root,COG4122@1|root,COG0110@2|Bacteria,COG4122@2|Bacteria,4NNTF@976|Bacteroidetes,1I232@117743|Flavobacteriia,2NWA0@237|Flavobacterium	976|Bacteroidetes	S	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158347_k127_3765920_0	314275.MADE_000001022350	2.836e-70	246.0	2BDYA@1|root,327NJ@2|Bacteria,1RC23@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR25158347_k127_3765920_1	1250278.JQNQ01000001_gene3299	8.771e-53	199.0	COG0463@1|root,COG0463@2|Bacteria,4NQNJ@976|Bacteroidetes,1I1HE@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_3765920_2	865937.Gilli_0672	2.666e-51	184.0	COG0463@1|root,COG0463@2|Bacteria,4NQNJ@976|Bacteroidetes,1I2VG@117743|Flavobacteriia,2P71U@244698|Gillisia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_3766735_0	1232410.KI421424_gene1615	2.119e-75	265.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,43TJ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158347_k127_3766735_1	457570.Nther_1651	8.023e-10	65.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158347_k127_3767004_0	1201288.M900_2215	1.298e-71	251.0	COG4292@1|root,COG4292@2|Bacteria,1QWAK@1224|Proteobacteria	1224|Proteobacteria	S	K channel, inward rectifier, conserved region 2 domain protein	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK,LtrA
SRR25158347_k127_3767004_1	1038858.AXBA01000012_gene1786	0.0007745	42.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2U9U1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158347_k127_3767065_0	349124.Hhal_1886	8.675e-29	128.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3769352_1	1353276.JADR01000002_gene2029	2.087e-39	152.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
SRR25158347_k127_3769352_0	1168034.FH5T_16280	5.629e-67	232.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,2FMYB@200643|Bacteroidia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158347_k127_3769432_2	1122201.AUAZ01000010_gene2601	2.613e-06	56.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,46766@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
SRR25158347_k127_3769432_1	875454.BAEW01000001_gene237	1.046e-49	183.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,22FWZ@1570339|Peptoniphilaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158347_k127_3769432_0	56110.Oscil6304_5443	2.429e-85	303.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Hpt,Pkinase,Response_reg
SRR25158347_k127_3769997_0	264462.Bd0477	1.558e-28	122.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,42WAH@68525|delta/epsilon subdivisions,2MTKG@213481|Bdellovibrionales,2X5KM@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	MotA TolQ ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158347_k127_3769997_1	215803.DB30_6625	3.931e-22	101.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria,2YZ6J@29|Myxococcales	28221|Deltaproteobacteria	U	ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158347_k127_3769997_2	338966.Ppro_1236	6.302e-06	56.0	COG0810@1|root,COG0810@2|Bacteria,1QX76@1224|Proteobacteria,42V4D@68525|delta/epsilon subdivisions,2WRH8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	mxcH	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SRR25158347_k127_37707_0	1454004.AW11_01670	9.619e-127	410.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2W1P8@28216|Betaproteobacteria	28216|Betaproteobacteria	CT	Domain in cystathionine beta-synthase and other proteins.	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,CBS
SRR25158347_k127_37707_1	1121413.JMKT01000016_gene119	9.022e-42	160.0	COG1216@1|root,COG1887@1|root,COG1216@2|Bacteria,COG1887@2|Bacteria,1MX5Z@1224|Proteobacteria,42QVV@68525|delta/epsilon subdivisions,2WN0A@28221|Deltaproteobacteria,2M87B@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_2,Glycos_transf_1,Glycos_transf_2
SRR25158347_k127_3773883_0	502025.Hoch_6481	1.713e-58	214.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WN6T@28221|Deltaproteobacteria,2Z2ZA@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SRR25158347_k127_3773883_1	1121904.ARBP01000006_gene3930	1.722e-36	141.0	COG0346@1|root,COG0346@2|Bacteria,4NRR0@976|Bacteroidetes	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_3776608_0	246197.MXAN_3756	1.328e-51	201.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRR25158347_k127_3776608_1	1390370.O203_20435	1.68e-05	52.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1YD8I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	Inner membrane protein CreD	creD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
SRR25158347_k127_3778218_0	1118055.CAGU01000043_gene1470	1.336e-07	58.0	COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,24PHR@186801|Clostridia,22JGR@1570339|Peptoniphilaceae	186801|Clostridia	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_3779034_1	641112.ACOK01000119_gene1417	1.763e-10	67.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3WGZS@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
SRR25158347_k127_3779034_0	269796.Rru_A3110	3.623e-14	80.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,2JUNY@204441|Rhodospirillales	204441|Rhodospirillales	K	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
SRR25158347_k127_3779273_1	324057.Pjdr2_4470	1.945e-18	94.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,26S11@186822|Paenibacillaceae	91061|Bacilli	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158347_k127_3779273_0	1392490.JHZX01000001_gene3105	8.448e-79	285.0	COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,1IIQ5@117743|Flavobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C1
SRR25158347_k127_3779780_0	1229780.BN381_40078	1.638e-66	241.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,3UWXQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyltransferase like family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158347_k127_3780785_1	482537.XP_008580827.1	3.178e-09	67.0	COG0666@1|root,KOG0504@2759|Eukaryota,39JVB@33154|Opisthokonta,3BJQ0@33208|Metazoa,3CXAM@33213|Bilateria,48AB5@7711|Chordata,490N8@7742|Vertebrata,3JDE8@40674|Mammalia,35EVD@314146|Euarchontoglires	33208|Metazoa	S	Ankyrin repeat and SOCS box	ASB3	GO:0000151,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0032446,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044424,GO:0044444,GO:0044464,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1902494,GO:1990234	-	ko:K10325	-	-	-	-	ko00000,ko04121	-	-	-	Ank_2,Ank_3,Ank_4,SOCS_box
SRR25158347_k127_3780785_0	1202532.FF52_07159	1.45e-14	75.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia,2NSMF@237|Flavobacterium	976|Bacteroidetes	H	synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
SRR25158347_k127_3782161_1	317655.Sala_0068	1.909e-13	70.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2TTXT@28211|Alphaproteobacteria,2K2IC@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158347_k127_3782161_0	1173028.ANKO01000127_gene4122	1.901e-56	209.0	COG0515@1|root,COG0642@1|root,COG2208@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3899@2|Bacteria,1GHS3@1117|Cyanobacteria,1HF2M@1150|Oscillatoriales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase
SRR25158347_k127_3782518_0	497321.C664_16865	1.059e-96	333.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KVUY@206389|Rhodocyclales	206389|Rhodocyclales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
SRR25158347_k127_3783239_0	172045.KS04_15955	1.543e-06	59.0	COG0642@1|root,COG2205@2|Bacteria,4NP4C@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_3783392_0	391625.PPSIR1_13195	7.054e-40	160.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,PQQ_2
SRR25158347_k127_3783659_0	1121035.AUCH01000003_gene1139	6.982e-78	269.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KVUY@206389|Rhodocyclales	206389|Rhodocyclales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,NIT
SRR25158347_k127_3783659_1	349521.HCH_06584	4.171e-67	239.0	COG0596@1|root,COG0596@2|Bacteria,1QTUG@1224|Proteobacteria,1T43S@1236|Gammaproteobacteria,1XR4Q@135619|Oceanospirillales	135619|Oceanospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158347_k127_3783659_2	1127673.GLIP_3597	3.93e-08	58.0	COG2319@1|root,COG2319@2|Bacteria,1NVWH@1224|Proteobacteria,1SPN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3786179_1	643867.Ftrac_3340	3.899e-06	48.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158347_k127_3787136_0	926569.ANT_22130	3.234e-57	204.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
SRR25158347_k127_3787136_1	316274.Haur_4052	1.607e-33	140.0	COG1752@1|root,COG1752@2|Bacteria,2GAAT@200795|Chloroflexi,374T8@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158347_k127_3787174_0	1128421.JAGA01000003_gene3503	1.038e-138	453.0	COG0766@1|root,COG0766@2|Bacteria,2NNUV@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
SRR25158347_k127_378759_0	595460.RRSWK_02342	2.439e-81	280.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158347_k127_378759_2	1313421.JHBV01000030_gene2091	4.781e-14	77.0	2DPWK@1|root,32UMZ@2|Bacteria	2|Bacteria	S	Nucleoside 2-deoxyribosyltransferase like	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyri_tr2
SRR25158347_k127_3787916_2	573413.Spirs_3209	0.0001024	46.0	COG1160@1|root,COG1160@2|Bacteria,2J5GG@203691|Spirochaetes	203691|Spirochaetes	I	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158347_k127_3787916_1	469606.FSCG_00134	1.104e-37	149.0	COG0344@1|root,COG0344@2|Bacteria,379CX@32066|Fusobacteria	32066|Fusobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158347_k127_3787916_0	1121930.AQXG01000004_gene2979	2.179e-39	151.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158347_k127_3788846_0	1123274.KB899423_gene1624	2.603e-23	110.0	COG0840@1|root,COG0840@2|Bacteria,2J5BF@203691|Spirochaetes	203691|Spirochaetes	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
SRR25158347_k127_3789226_2	1449063.JMLS01000004_gene2424	3.042e-51	184.0	COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,4HE5F@91061|Bacilli,26TKM@186822|Paenibacillaceae	91061|Bacilli	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
SRR25158347_k127_3789226_1	945713.IALB_2439	4.026e-63	220.0	2DM8M@1|root,326GM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_3789226_0	580331.Thit_0485	1.986e-90	307.0	COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia,42G63@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SRR25158347_k127_3789461_0	153948.NAL212_2692	3.413e-56	199.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VKHF@28216|Betaproteobacteria,373EY@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
SRR25158347_k127_3789461_1	1133849.O3I_015930	4.987e-14	83.0	COG4529@1|root,COG4529@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRR25158347_k127_380952_0	483219.LILAB_18805	1.857e-106	353.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YTZG@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158347_k127_385759_0	523794.Lebu_2148	4.222e-79	270.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rgpB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
SRR25158347_k127_385759_1	709991.Odosp_0131	2.113e-60	216.0	COG0463@1|root,COG0463@2|Bacteria,4NK1T@976|Bacteroidetes,2FPN1@200643|Bacteroidia,22YJG@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_39041_0	85929.N1QFR1	3.106e-08	66.0	COG5271@1|root,KOG1808@2759|Eukaryota,38FBP@33154|Opisthokonta,3NUU0@4751|Fungi,3QMXW@4890|Ascomycota,1ZXRQ@147541|Dothideomycetes,3MI7Q@451867|Dothideomycetidae	4751|Fungi	S	Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits	MDN1	GO:0000027,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K14572	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	AAA_5,VWA
SRR25158347_k127_390949_1	1121904.ARBP01000008_gene3223	8e-50	196.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47MXR@768503|Cytophagia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
SRR25158347_k127_390949_0	1443665.JACA01000033_gene1789	1.476e-63	223.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,1I7QT@117743|Flavobacteriia,2YIRG@290174|Aquimarina	976|Bacteroidetes	O	Holliday junction DNA helicase ruvB N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158347_k127_390949_2	1458462.JNLK01000001_gene827	8.417e-11	63.0	COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,24BQK@186801|Clostridia,27JWJ@186928|unclassified Lachnospiraceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158347_k127_394406_0	1399115.U719_01625	6.363e-19	100.0	COG0433@1|root,COG0433@2|Bacteria,1UPB7@1239|Firmicutes,4IV60@91061|Bacilli	91061|Bacilli	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_395479_0	909663.KI867150_gene491	1.566e-37	157.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_397460_0	1089547.KB913013_gene3536	4.836e-58	207.0	COG0210@1|root,COG0210@2|Bacteria,4PMM6@976|Bacteroidetes	976|Bacteroidetes	L	COGs COG0210 Superfamily I DNA and RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C
SRR25158347_k127_397460_1	404589.Anae109_1980	7.048e-05	55.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SRR25158347_k127_399062_0	1121396.KB893077_gene741	1.649e-132	428.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158347_k127_399062_1	886379.AEWI01000013_gene2130	1.833e-47	171.0	28IYQ@1|root,2Z8WB@2|Bacteria,4NKIJ@976|Bacteroidetes,2FW30@200643|Bacteroidia	976|Bacteroidetes	S	Type II restriction endonuclease EcoO109I	-	-	-	-	-	-	-	-	-	-	-	-	RE_EcoO109I
SRR25158347_k127_399313_0	1122217.KB899584_gene107	2.232e-97	327.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158347_k127_399614_1	1245469.S58_25010	2.83e-44	166.0	COG0662@1|root,COG0662@2|Bacteria,1QCVX@1224|Proteobacteria,2U0QW@28211|Alphaproteobacteria,3JWFF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158347_k127_399614_0	1245469.S58_25000	1.497e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,1PMAE@1224|Proteobacteria,2U57K@28211|Alphaproteobacteria,3JWW2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158347_k127_399614_2	1245469.S58_24990	5.099e-07	54.0	COG4976@1|root,COG4976@2|Bacteria,1QW8Z@1224|Proteobacteria,2TWTG@28211|Alphaproteobacteria,3K6P9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158347_k127_400759_1	1123504.JQKD01000002_gene3810	1.23e-22	98.0	COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,2VNTX@28216|Betaproteobacteria,4ACN4@80864|Comamonadaceae	28216|Betaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_400759_0	1443665.JACA01000003_gene994	8.9e-120	391.0	COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,1HY8V@117743|Flavobacteriia,2YJ49@290174|Aquimarina	976|Bacteroidetes	E	Glutaminase	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
SRR25158347_k127_402824_0	521045.Kole_1174	5.28e-106	357.0	COG0366@1|root,COG0366@2|Bacteria,2GCN1@200918|Thermotogae	200918|Thermotogae	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
SRR25158347_k127_403483_0	1237149.C900_01793	8.103e-09	68.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SRR25158347_k127_405736_0	1254432.SCE1572_08850	3.254e-151	487.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2Z30G@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158347_k127_406021_1	344747.PM8797T_29278	9.749e-77	261.0	COG2223@1|root,COG2223@2|Bacteria,2IYP8@203682|Planctomycetes	203682|Planctomycetes	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRR25158347_k127_406021_2	497964.CfE428DRAFT_4921	4.627e-23	115.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
SRR25158347_k127_406021_0	643473.KB235930_gene308	6.625e-97	323.0	COG1249@1|root,COG1249@2|Bacteria,1G0W0@1117|Cyanobacteria,1HM2V@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_409060_1	370438.PTH_1746	9.084e-67	235.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158347_k127_409060_2	1519464.HY22_09580	1.069e-56	205.0	COG1011@1|root,COG1011@2|Bacteria,1FF2T@1090|Chlorobi	1090|Chlorobi	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158347_k127_409060_0	717773.Thicy_0588	7.065e-124	403.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales	72273|Thiotrichales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158347_k127_410549_0	35725.K2RDN4	2.636e-05	55.0	COG4850@1|root,2RYXR@2759|Eukaryota,39UK2@33154|Opisthokonta,3NVID@4751|Fungi,3QJYW@4890|Ascomycota,200S2@147541|Dothideomycetes	4751|Fungi	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158347_k127_410918_0	1173027.Mic7113_2279	1.481e-53	198.0	COG0300@1|root,COG0300@2|Bacteria,1G1Z0@1117|Cyanobacteria,1H9PX@1150|Oscillatoriales	1117|Cyanobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_412005_0	1353529.M899_0920	6.748e-110	360.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42Z9B@68525|delta/epsilon subdivisions,2MTJK@213481|Bdellovibrionales,2WMPJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158347_k127_412005_1	313606.M23134_07021	3.5e-19	90.0	COG0061@1|root,COG0061@2|Bacteria,4NG3P@976|Bacteroidetes,47M9J@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
SRR25158347_k127_416289_0	641491.DND132_1799	3.19e-40	159.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2WIVQ@28221|Deltaproteobacteria,2M8ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM Phosphoserine phosphatase SerB	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
SRR25158347_k127_42405_0	883110.HMPREF9260_01383	1.445e-17	93.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HF6X@91061|Bacilli,27EDS@186827|Aerococcaceae	91061|Bacilli	L	Microtubule binding	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA,IstB_IS21
SRR25158347_k127_428510_0	931277.C448_09422	2.734e-22	111.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_429728_1	1203554.HMPREF1476_02233	6.946e-12	72.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,4PQSW@995019|Sutterellaceae	28216|Betaproteobacteria	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158347_k127_429728_0	1519464.HY22_10540	6.957e-192	612.0	COG0029@1|root,COG0029@2|Bacteria,1FD79@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158347_k127_433869_2	2880.D8LQV3	4.335e-09	58.0	COG0516@1|root,KOG2550@2759|Eukaryota	2759|Eukaryota	F	IMP dehydrogenase activity	IMPDH2	GO:0000166,GO:0000323,GO:0000785,GO:0000902,GO:0000904,GO:0001654,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003723,GO:0003729,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006950,GO:0006955,GO:0007154,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007423,GO:0007623,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009735,GO:0009987,GO:0009991,GO:0010033,GO:0012505,GO:0016020,GO:0016043,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022008,GO:0022607,GO:0030030,GO:0030141,GO:0030154,GO:0030182,GO:0030447,GO:0031175,GO:0031347,GO:0031349,GO:0031410,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032940,GO:0032943,GO:0032989,GO:0032990,GO:0033554,GO:0034097,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0035578,GO:0035690,GO:0035821,GO:0036094,GO:0036170,GO:0036180,GO:0036230,GO:0040007,GO:0040011,GO:0042119,GO:0042221,GO:0042278,GO:0042330,GO:0042451,GO:0042455,GO:0042493,GO:0042582,GO:0042594,GO:0043010,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043473,GO:0043933,GO:0044003,GO:0044085,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044416,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0046903,GO:0048066,GO:0048468,GO:0048511,GO:0048513,GO:0048518,GO:0048583,GO:0048584,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052251,GO:0052255,GO:0052509,GO:0052510,GO:0055086,GO:0055114,GO:0060041,GO:0060205,GO:0061564,GO:0065003,GO:0065007,GO:0070013,GO:0070661,GO:0070670,GO:0070887,GO:0071310,GO:0071345,GO:0071353,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0075136,GO:0080134,GO:0090407,GO:0097159,GO:0097485,GO:0097708,GO:0099503,GO:0101002,GO:0120036,GO:0120039,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158347_k127_433869_0	289376.THEYE_A0617	1.051e-198	636.0	COG0173@1|root,COG0173@2|Bacteria,3J0FR@40117|Nitrospirae	40117|Nitrospirae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158347_k127_433869_1	485916.Dtox_3070	2.364e-73	256.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,260MI@186807|Peptococcaceae	186801|Clostridia	T	PFAM PhoH family protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158347_k127_435996_0	640512.BC1003_3000	6.433e-08	64.0	28IA9@1|root,2Z9M7@2|Bacteria,1QTVI@1224|Proteobacteria,2VMWA@28216|Betaproteobacteria,1K37W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
SRR25158347_k127_438355_0	1132442.KB889752_gene346	1.136e-82	285.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9
SRR25158347_k127_438355_1	1304888.ATWF01000001_gene1276	1.415e-73	270.0	COG0004@1|root,COG0004@2|Bacteria,2GER5@200930|Deferribacteres	2|Bacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,EAL,GGDEF,HATPase_c,HisKA,HisKA_3,MCPsignal,PAS_9,Response_reg
SRR25158347_k127_440484_1	640081.Dsui_1710	5.393e-12	76.0	COG0840@1|root,COG3829@1|root,COG5000@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KU84@206389|Rhodocyclales	206389|Rhodocyclales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS,PAS_9,TarH
SRR25158347_k127_440484_0	1123368.AUIS01000004_gene201	1.872e-73	252.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,2NCUA@225057|Acidithiobacillales	225057|Acidithiobacillales	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158347_k127_445423_1	1033740.CAEW01000001_gene1236	2.245e-08	57.0	2EGHB@1|root,33A9F@2|Bacteria,1UHU5@1239|Firmicutes,4IUGQ@91061|Bacilli,26IHS@186818|Planococcaceae	91061|Bacilli	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
SRR25158347_k127_445423_0	748247.AZKH_0193	7.759e-168	538.0	COG0784@1|root,COG2197@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWN@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
SRR25158347_k127_446499_0	477974.Daud_0643	4.408e-07	51.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,262SV@186807|Peptococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158347_k127_447081_1	313606.M23134_04574	2.763e-13	70.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia	976|Bacteroidetes	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
SRR25158347_k127_447081_0	1499967.BAYZ01000009_gene5309	2.983e-79	277.0	COG0642@1|root,COG2205@2|Bacteria,2NR1F@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_447081_2	999415.HMPREF9943_01345	2.436e-05	52.0	COG0642@1|root,COG2205@2|Bacteria,1V0S7@1239|Firmicutes,3VQ3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
SRR25158347_k127_450265_0	1123372.AUIT01000005_gene1247	3.514e-13	81.0	COG3170@1|root,COG3170@2|Bacteria,2GGY6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_450603_0	1229909.NSED_02315	1.149e-45	167.0	arCOG08731@1|root,arCOG08731@2157|Archaea,41STT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_450603_2	1131266.ARWQ01000010_gene42	1.174e-13	74.0	arCOG10525@1|root,arCOG10525@2157|Archaea,41SUR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_450603_1	1229909.NSED_02325	8.057e-45	163.0	COG0197@1|root,arCOG04113@2157|Archaea,41SKN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158347_k127_454345_1	525904.Tter_2109	5.145e-16	88.0	COG1470@1|root,COG3664@1|root,COG1470@2|Bacteria,COG3664@2|Bacteria,2NQ48@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,NPCBM_assoc,PEGA
SRR25158347_k127_454345_2	1068980.ARVW01000001_gene6099	1.816e-12	76.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4E2V5@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158347_k127_454345_3	67593.Physo141732	8.955e-06	54.0	2C3YR@1|root,2S6K8@2759|Eukaryota,3QFRG@4776|Peronosporales	4776|Peronosporales	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
SRR25158347_k127_454345_0	1322246.BN4_12152	2.629e-31	132.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42UBK@68525|delta/epsilon subdivisions,2WQU5@28221|Deltaproteobacteria,2M9FJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
SRR25158347_k127_455754_2	1124780.ANNU01000087_gene1452	0.0006171	45.0	2ERRS@1|root,33JAZ@2|Bacteria,4NY8B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_455754_1	1396141.BATP01000006_gene5501	3.276e-11	72.0	2CNXM@1|root,32SI1@2|Bacteria,46SZC@74201|Verrucomicrobia,2IUHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_455754_0	998674.ATTE01000001_gene284	4.851e-26	113.0	COG4850@1|root,COG4850@2|Bacteria,1R3ST@1224|Proteobacteria,1RYC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158347_k127_460419_0	1296416.JACB01000063_gene2012	4.246e-108	361.0	COG0265@1|root,COG0265@2|Bacteria,4NJVK@976|Bacteroidetes,1I963@117743|Flavobacteriia,2YKKS@290174|Aquimarina	976|Bacteroidetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
SRR25158347_k127_460932_0	44251.PDUR_24900	5.106e-102	342.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli,26T5K@186822|Paenibacillaceae	91061|Bacilli	GM	ABC transporter	rgpD	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158347_k127_460932_1	349520.PPE_04337	1.963e-31	124.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,4HB9R@91061|Bacilli,26UDQ@186822|Paenibacillaceae	91061|Bacilli	U	Transport permease protein	rfbA5	-	-	ko:K09690,ko:K09692	ko02010,map02010	M00250,M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103,3.A.1.104	-	-	ABC2_membrane
SRR25158347_k127_462654_1	398512.JQKC01000026_gene3796	3.871e-36	156.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WNRY@541000|Ruminococcaceae	186801|Clostridia	NT	Tar ligand binding domain homologue	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
SRR25158347_k127_462654_0	240292.Ava_5017	1.634e-64	224.0	COG1045@1|root,COG1045@2|Bacteria,1G2SI@1117|Cyanobacteria,1HJA3@1161|Nostocales	1117|Cyanobacteria	E	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
SRR25158347_k127_471644_0	1165841.SULAR_07805	1.999e-19	96.0	COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,42WVW@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158347_k127_471969_0	580331.Thit_1249	6.652e-118	396.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,42EQT@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM Magnesium chelatase, ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158347_k127_472298_1	572479.Hprae_0685	2.328e-12	72.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WB7F@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
SRR25158347_k127_472298_0	907348.TresaDRAFT_1431	1.737e-18	89.0	COG1664@1|root,COG1664@2|Bacteria,2J861@203691|Spirochaetes	203691|Spirochaetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158347_k127_47557_0	1232437.KL661988_gene243	1.163e-50	201.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MHXT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,GAF_2,HAMP,HATPase_c,HisKA,Hpt,MASE2,PAS_4,PAS_9,Response_reg
SRR25158347_k127_475764_0	1298593.TOL_1408	4.121e-53	196.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XH9W@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158347_k127_475842_0	926549.KI421517_gene192	1.811e-06	60.0	COG1366@1|root,COG1366@2|Bacteria,4NVHQ@976|Bacteroidetes,47RVX@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_476152_0	857087.Metme_3844	6.342e-55	197.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XDZX@135618|Methylococcales	135618|Methylococcales	P	PFAM Sulphate transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
SRR25158347_k127_482916_0	247490.KSU1_C1278	8.553e-109	361.0	COG0527@1|root,COG0527@2|Bacteria,2IY8N@203682|Planctomycetes	203682|Planctomycetes	E	aspartate kinase, monofunctional class	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158347_k127_484832_2	1151292.QEW_0809	0.0003764	51.0	COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,24D4U@186801|Clostridia,25RE7@186804|Peptostreptococcaceae	186801|Clostridia	S	Protease prsW family	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158347_k127_484832_1	929556.Solca_4212	6.005e-10	64.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1ITMF@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the ClpS family	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158347_k127_484832_0	2002.JOEQ01000004_gene2591	2.39e-36	153.0	28IGI@1|root,2Z8HZ@2|Bacteria,2H5CR@201174|Actinobacteria,4EGEK@85012|Streptosporangiales	201174|Actinobacteria	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
SRR25158347_k127_486927_0	523794.Lebu_0033	1.113e-39	162.0	COG3950@1|root,COG3950@2|Bacteria,3785E@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SRR25158347_k127_486927_1	221288.JH992901_gene2954	1.536e-13	76.0	COG1403@1|root,COG1403@2|Bacteria,1G76A@1117|Cyanobacteria	1117|Cyanobacteria	V	TIGRFAM TIGR02646 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_488607_1	877418.ATWV01000003_gene650	2.276e-67	241.0	COG2114@1|root,COG2114@2|Bacteria,2J5GP@203691|Spirochaetes	2|Bacteria	T	guanylate cyclase catalytic domain	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158347_k127_488607_0	1237149.C900_02666	3.779e-136	440.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,47M7J@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
SRR25158347_k127_489084_1	667014.Thein_0735	8.324e-58	206.0	COG2089@1|root,COG2089@2|Bacteria	2|Bacteria	M	N-acylneuraminate-9-phosphate synthase activity	spsE	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR25158347_k127_489084_2	883.DvMF_1893	4.678e-45	171.0	COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,42UCD@68525|delta/epsilon subdivisions,2WR2M@28221|Deltaproteobacteria,2MAS1@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
SRR25158347_k127_489084_0	631362.Thi970DRAFT_02566	4.374e-135	443.0	COG4310@1|root,COG4310@2|Bacteria,1NDWT@1224|Proteobacteria,1RRQM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
SRR25158347_k127_489084_3	536232.CLM_3076	2.315e-05	47.0	COG0287@1|root,COG2348@1|root,COG0287@2|Bacteria,COG2348@2|Bacteria,1V67I@1239|Firmicutes,24FI6@186801|Clostridia,36HXS@31979|Clostridiaceae	186801|Clostridia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158347_k127_4909_0	264462.Bd3071	4.583e-17	93.0	COG1352@1|root,COG1352@2|Bacteria,1QY2J@1224|Proteobacteria,43AK1@68525|delta/epsilon subdivisions,2MTJG@213481|Bdellovibrionales,2X60B@28221|Deltaproteobacteria	213481|Bdellovibrionales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_492773_0	243365.CV_3792	2.54e-69	241.0	COG0586@1|root,COG0586@2|Bacteria,1R6V4@1224|Proteobacteria,2VMXP@28216|Betaproteobacteria,2KQ67@206351|Neisseriales	206351|Neisseriales	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158347_k127_492773_2	515635.Dtur_0891	2.386e-27	118.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_4,HNH_5
SRR25158347_k127_492773_1	1521187.JPIM01000001_gene876	5.237e-30	128.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,375ER@32061|Chloroflexia	32061|Chloroflexia	G	PFAM inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158347_k127_493921_0	756272.Plabr_3346	7.236e-107	356.0	COG0733@1|root,COG0733@2|Bacteria,2J29X@203682|Planctomycetes	203682|Planctomycetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
SRR25158347_k127_494999_0	425104.Ssed_2035	2.845e-43	174.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,2QD48@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,PEGA,Pkinase
SRR25158347_k127_495232_2	1245469.S58_24990	9.085e-18	84.0	COG4976@1|root,COG4976@2|Bacteria,1QW8Z@1224|Proteobacteria,2TWTG@28211|Alphaproteobacteria,3K6P9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158347_k127_495232_0	1038866.KB902813_gene2084	4.09e-67	243.0	COG2227@1|root,COG2227@2|Bacteria,1R7ZA@1224|Proteobacteria,2U2FV@28211|Alphaproteobacteria,3JRTB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158347_k127_495232_1	1380394.JADL01000001_gene2771	2.137e-34	145.0	2B4Y0@1|root,31XQZ@2|Bacteria,1MZ15@1224|Proteobacteria,2US19@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_495283_0	159087.Daro_4059	1.762e-110	364.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria,2VZKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SRR25158347_k127_495283_1	290512.Paes_2385	2.195e-49	183.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_498089_0	1242864.D187_007012	2.426e-35	155.0	COG4223@1|root,COG4223@2|Bacteria,1NDYH@1224|Proteobacteria,433KY@68525|delta/epsilon subdivisions	1224|Proteobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_498896_0	1184267.A11Q_1672	2.581e-112	372.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2MSZ3@213481|Bdellovibrionales,2WJZK@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SRR25158347_k127_498896_1	765869.BDW_12780	6.609e-18	86.0	COG0745@1|root,COG0745@2|Bacteria,1R9AZ@1224|Proteobacteria,42NYS@68525|delta/epsilon subdivisions,2MUSE@213481|Bdellovibrionales,2X6B0@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158347_k127_502840_1	395493.BegalDRAFT_3522	2.18e-32	132.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,45ZTY@72273|Thiotrichales	72273|Thiotrichales	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
SRR25158347_k127_502840_0	1283300.ATXB01000001_gene2076	1.84e-131	429.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1XEX3@135618|Methylococcales	135618|Methylococcales	K	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF3335
SRR25158347_k127_502840_2	313606.M23134_05862	3.729e-11	71.0	COG4733@1|root,COG4733@2|Bacteria,4NH5S@976|Bacteroidetes,47JQW@768503|Cytophagia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_50453_0	1045856.EcWSU1_02962	1.398e-139	448.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,3X22B@547|Enterobacter	1236|Gammaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSDY_1059.SDY_2206,iSF_1195.SF2102,iSFxv_1172.SFxv_2338,iS_1188.S2225	NTP_transferase
SRR25158347_k127_50453_1	357809.Cphy_3680	2.337e-40	151.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,21XP7@1506553|Lachnoclostridium	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158347_k127_504672_1	1125863.JAFN01000001_gene796	7.46e-36	153.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_504672_0	237368.SCABRO_01577	5.335e-173	552.0	COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158347_k127_508595_0	227086.JGI_V11_76402	1.41e-12	68.0	28M0P@1|root,2QTHF@2759|Eukaryota	2759|Eukaryota	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158347_k127_509096_0	889378.Spiaf_0471	2.603e-47	186.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,2J5GP@203691|Spirochaetes	203691|Spirochaetes	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
SRR25158347_k127_510398_0	448385.sce3252	2.834e-18	97.0	293FU@1|root,2ZQY7@2|Bacteria,1PAUE@1224|Proteobacteria,437XW@68525|delta/epsilon subdivisions,2X9RN@28221|Deltaproteobacteria,2YUR8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_510638_1	1121439.dsat_0939	1.872e-09	64.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1MU9B@1224|Proteobacteria,42NNT@68525|delta/epsilon subdivisions,2WJDP@28221|Deltaproteobacteria,2M8A1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,Hemerythrin,MCPsignal
SRR25158347_k127_510638_0	159087.Daro_1752	5.644e-40	155.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,2KVNR@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158347_k127_511010_1	32049.SYNPCC7002_A2863	1.847e-59	214.0	COG2199@1|root,COG3706@2|Bacteria,1G4NI@1117|Cyanobacteria,1H2FI@1129|Synechococcus	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158347_k127_511010_0	156889.Mmc1_1821	1.125e-79	278.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,PAS_7
SRR25158347_k127_514073_2	1244869.H261_16992	7.906e-35	151.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2JQ05@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_514073_0	1298593.TOL_3012	4.143e-123	398.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,1RRMA@1236|Gammaproteobacteria,1XJ20@135619|Oceanospirillales	135619|Oceanospirillales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158347_k127_514073_4	522306.CAP2UW1_4385	2.482e-05	55.0	2CJ8Z@1|root,32WUG@2|Bacteria,1N1PS@1224|Proteobacteria,2VUYW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_514073_1	1121342.AUCO01000014_gene1877	1.45e-59	212.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36ICC@31979|Clostridiaceae	186801|Clostridia	S	hemolysin III	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158347_k127_514073_3	767434.Fraau_1153	1.57e-10	67.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,1S9KM@1236|Gammaproteobacteria,1X7M1@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158347_k127_514450_1	225849.swp_1998	1.2e-19	89.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,2Q9GU@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158347_k127_514450_0	868595.Desca_0199	3.829e-49	181.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,260QW@186807|Peptococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158347_k127_514450_2	1089439.KB902251_gene1572	3.463e-07	54.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,46194@72273|Thiotrichales	72273|Thiotrichales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158347_k127_515378_1	1499967.BAYZ01000190_gene3815	2.351e-35	141.0	COG3222@1|root,COG3222@2|Bacteria,2NRHT@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
SRR25158347_k127_515378_0	1121930.AQXG01000010_gene3117	4.973e-115	379.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,1IPEG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
SRR25158347_k127_515500_1	1041930.Mtc_1597	1.92e-101	336.0	COG2021@1|root,arCOG00627@2157|Archaea,2XTYY@28890|Euryarchaeota,2N9C1@224756|Methanomicrobia	224756|Methanomicrobia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,CBS
SRR25158347_k127_515500_0	635013.TherJR_2226	1.092e-211	666.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,26060@186807|Peptococcaceae	186801|Clostridia	E	PFAM Cys Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158347_k127_515500_2	138119.DSY4236	1.264e-68	235.0	28NIH@1|root,2ZBJX@2|Bacteria,1V1SN@1239|Firmicutes,24DH3@186801|Clostridia,261JZ@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_515500_3	1411685.U062_00129	7.505e-33	128.0	COG0655@1|root,COG0655@2|Bacteria,1RAP5@1224|Proteobacteria,1S3B1@1236|Gammaproteobacteria,1J633@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158347_k127_515842_0	35128.Thaps11282	3.686e-50	193.0	2C3KC@1|root,2SEFD@2759|Eukaryota	2759|Eukaryota	S	Capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth,Gly_transf_sug
SRR25158347_k127_515842_2	1196322.A370_05594	9.607e-12	72.0	2C6EQ@1|root,32XHW@2|Bacteria,1VEAK@1239|Firmicutes,24NWK@186801|Clostridia,36PVU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_515842_1	279010.BL00083	7.886e-24	109.0	COG5444@1|root,COG5444@2|Bacteria	2|Bacteria	UW	nuclease activity	-	-	-	ko:K21493	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	LXG,Ntox50,PT-TG
SRR25158347_k127_517787_0	395493.BegalDRAFT_0808	5.021e-85	294.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T3S9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158347_k127_518172_3	1121930.AQXG01000016_gene1820	3.296e-06	50.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1ITNU@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158347_k127_518172_2	1487953.JMKF01000006_gene5627	1.761e-06	53.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158347_k127_518172_0	880073.Calab_0899	1.392e-151	493.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,Pribosyltran,RQC,RecQ_Zn_bind
SRR25158347_k127_518172_1	203124.Tery_4158	1.051e-46	177.0	COG3000@1|root,COG3000@2|Bacteria,1GA5F@1117|Cyanobacteria,1HHNH@1150|Oscillatoriales	1117|Cyanobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158347_k127_518309_0	382464.ABSI01000013_gene1716	4.279e-59	216.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158347_k127_518309_1	1288826.MSNKSG1_01543	1.141e-55	199.0	2B7YH@1|root,3215N@2|Bacteria,1RJP9@1224|Proteobacteria,1S6AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158347_k127_518309_2	439235.Dalk_4289	3.66e-50	184.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2MJBT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158347_k127_519885_2	929703.KE386491_gene3136	1.061e-75	265.0	COG2267@1|root,COG2267@2|Bacteria,4NK38@976|Bacteroidetes,47N7P@768503|Cytophagia	976|Bacteroidetes	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
SRR25158347_k127_519885_1	1121904.ARBP01000015_gene206	1.704e-79	273.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47KRK@768503|Cytophagia	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158347_k127_519885_0	929556.Solca_0927	4.881e-92	317.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158347_k127_519885_3	1122134.KB893650_gene59	5.594e-64	227.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1XHBC@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158347_k127_526799_2	1125863.JAFN01000001_gene2858	7.074e-74	274.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42RAY@68525|delta/epsilon subdivisions,2WMP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_526799_0	744872.Spica_2165	1.874e-114	383.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158347_k127_526799_1	497965.Cyan7822_0992	5.357e-104	351.0	COG4402@1|root,COG4402@2|Bacteria,1G1RZ@1117|Cyanobacteria,3KGC8@43988|Cyanothece	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SRR25158347_k127_532269_0	247634.GPB2148_1704	3.347e-59	220.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1J52X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158347_k127_533297_0	1307761.L21SP2_1414	5.525e-11	72.0	COG0664@1|root,COG0664@2|Bacteria,2J6ZR@203691|Spirochaetes	203691|Spirochaetes	K	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_535716_1	551275.KB899547_gene589	8.987e-10	62.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,43W5A@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158347_k127_535716_0	331678.Cphamn1_1066	9.422e-57	208.0	COG0841@1|root,COG0841@2|Bacteria,1FEYE@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_536316_1	716544.wcw_1745	2.958e-48	181.0	COG0566@1|root,COG0566@2|Bacteria,2JFQK@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU_1	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158347_k127_536316_0	1121324.CLIT_13c02280	7.564e-63	225.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25QYD@186804|Peptostreptococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR25158347_k127_537508_2	5762.XP_002678687.1	1.416e-24	107.0	COG2896@1|root,KOG2876@2759|Eukaryota	2759|Eukaryota	H	cyclic pyranopterin monophosphate synthase activity	MOCS1	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0016830,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051189,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0061798,GO:0061799,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	4.1.99.22,4.6.1.17	ko:K03637,ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,MoaC,Mob_synth_C,Radical_SAM
SRR25158347_k127_537508_1	1120973.AQXL01000133_gene1710	2.85e-29	122.0	COG2030@1|root,COG2030@2|Bacteria,1VGYS@1239|Firmicutes,4HJK1@91061|Bacilli	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158347_k127_537508_0	1382306.JNIM01000001_gene3888	3.465e-33	132.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158347_k127_537508_3	400682.PAC_15703209	5.012e-13	75.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15503,ko:K16726,ko:K21440	-	-	-	-	ko00000,ko01009,ko03036,ko03400,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158347_k127_538520_1	998088.B565_3175	1.208e-43	162.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,1Y5YH@135624|Aeromonadales	135624|Aeromonadales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158347_k127_538520_2	1123487.KB892835_gene3481	1.603e-06	56.0	COG3113@1|root,COG3113@2|Bacteria,1NI22@1224|Proteobacteria,2WGYP@28216|Betaproteobacteria,2KZWX@206389|Rhodocyclales	206389|Rhodocyclales	S	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158347_k127_538520_0	1122236.KB905141_gene1636	9.667e-52	194.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KNFY@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158347_k127_541102_1	330214.NIDE1162	5.505e-11	70.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10
SRR25158347_k127_541102_0	1158345.JNLL01000001_gene1207	4.443e-78	271.0	COG0339@1|root,COG0339@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158347_k127_545064_2	879308.HMPREF9130_1472	9.785e-14	76.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,22G0M@1570339|Peptoniphilaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158347_k127_545064_1	7668.SPU_018651-tr	6.03e-17	87.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
SRR25158347_k127_545064_0	386456.JQKN01000015_gene2930	7.283e-27	113.0	COG0784@1|root,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158347_k127_546355_3	927658.AJUM01000042_gene1744	3.614e-11	70.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,2FUTH@200643|Bacteroidia,3XK19@558415|Marinilabiliaceae	976|Bacteroidetes	T	Histidine phosphatase superfamily (branch 1)	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158347_k127_546355_0	1173263.Syn7502_00058	7.832e-50	181.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
SRR25158347_k127_546355_2	1444711.CCJF01000005_gene1467	5.235e-26	112.0	COG2346@1|root,COG2346@2|Bacteria,2JH1G@204428|Chlamydiae	204428|Chlamydiae	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158347_k127_546355_1	1276246.SCULI_v1c10440	1.392e-38	154.0	COG1192@1|root,COG1192@2|Bacteria,3WTGQ@544448|Tenericutes	544448|Tenericutes	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_546355_5	1177154.Y5S_00785	6.155e-07	51.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XHNE@135619|Oceanospirillales	135619|Oceanospirillales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_547186_0	857087.Metme_2094	2.128e-78	285.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1RNGS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158347_k127_548958_2	1469948.JPNB01000003_gene91	5.525e-11	72.0	COG3291@1|root,COG3292@1|root,COG4733@1|root,COG5263@1|root,COG5492@1|root,COG3291@2|Bacteria,COG3292@2|Bacteria,COG4733@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,1UYJ9@1239|Firmicutes,248QE@186801|Clostridia,36KV6@31979|Clostridiaceae	186801|Clostridia	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,CW_binding_1,Glug,LRR_5,SLH
SRR25158347_k127_548958_0	189753.AXAS01000097_gene6017	1.182e-67	241.0	COG0491@1|root,COG0491@2|Bacteria,1MUSY@1224|Proteobacteria,2UBKW@28211|Alphaproteobacteria,3K2MP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158347_k127_548958_1	697281.Mahau_1467	8.357e-42	158.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158347_k127_553251_1	1249480.B649_08130	5.434e-14	79.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42UBD@68525|delta/epsilon subdivisions,2YRGP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
SRR25158347_k127_553251_0	1121930.AQXG01000004_gene2889	8.209e-30	124.0	COG2197@1|root,COG2197@2|Bacteria,4NF5P@976|Bacteroidetes,1IT9D@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_553350_1	877418.ATWV01000009_gene289	4.778e-08	64.0	COG1792@1|root,COG1792@2|Bacteria,2J77U@203691|Spirochaetes	203691|Spirochaetes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158347_k127_553350_0	1480694.DC28_01710	6.11e-42	156.0	COG1077@1|root,COG1077@2|Bacteria,2J59M@203691|Spirochaetes	203691|Spirochaetes	D	cell shape determining protein, MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158347_k127_557663_0	767817.Desgi_1008	2.004e-240	749.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,26092@186807|Peptococcaceae	186801|Clostridia	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR25158347_k127_557663_1	357808.RoseRS_2408	7.814e-31	130.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158347_k127_557797_0	1027273.GZ77_14480	2.819e-75	264.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XH5V@135619|Oceanospirillales	135619|Oceanospirillales	S	nucleoside-diphosphate sugar epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158347_k127_560668_0	880071.Fleli_1282	6.232e-07	61.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K13009	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Wzy_C,Wzy_C_2
SRR25158347_k127_565369_0	1294142.CINTURNW_4359	1.013e-20	100.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,36DJS@31979|Clostridiaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158347_k127_565369_2	1123518.ARWI01000001_gene2223	6.897e-06	51.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	FHA,Fer2,Fer2_BFD,Pyr_redox_2
SRR25158347_k127_565369_1	1192034.CAP_6980	1.061e-19	90.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales	28221|Deltaproteobacteria	S	Major facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158347_k127_566219_0	1123373.ATXI01000033_gene389	1.169e-87	297.0	COG1373@1|root,COG1373@2|Bacteria,2GGZJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158347_k127_566219_1	313594.PI23P_07980	3.226e-34	135.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	SEN0012	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158347_k127_568690_0	391612.CY0110_11187	3.861e-100	338.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1G4QT@1117|Cyanobacteria,3KKPT@43988|Cyanothece	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS_4,Pkinase
SRR25158347_k127_57096_0	179408.Osc7112_2432	1.662e-58	207.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria,1H9KV@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
SRR25158347_k127_57096_1	5888.CAK94506	3.54e-21	97.0	COG4642@1|root,COG5253@1|root,KOG0229@2759|Eukaryota,KOG0231@2759|Eukaryota,3ZD11@5878|Ciliophora	5878|Ciliophora	T	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_573185_0	665571.STHERM_c20270	0.0006345	53.0	COG2373@1|root,COG2373@2|Bacteria,2J8PU@203691|Spirochaetes	203691|Spirochaetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR25158347_k127_574769_0	1237149.C900_04503	1.963e-187	594.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,4NG4N@976|Bacteroidetes,47JUR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.7.2	ko:K00367	ko00910,ko01120,map00910,map01120	M00531	R00791	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
SRR25158347_k127_574814_0	761193.Runsl_0652	6.966e-110	368.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_575762_0	290512.Paes_2385	2.176e-58	213.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_57937_0	489825.LYNGBM3L_42570	4.866e-72	252.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1H9WN@1150|Oscillatoriales	1117|Cyanobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_57937_1	313606.M23134_01938	5.298e-34	141.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,Pkinase
SRR25158347_k127_581469_0	984262.SGRA_0114	6.179e-28	123.0	COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,1IX9C@117747|Sphingobacteriia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158347_k127_581469_1	35128.Thaps3323	6.764e-06	51.0	2BZA3@1|root,2QRM2@2759|Eukaryota,2XE2Y@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_58712_0	412419.BDU_160	4.502e-09	66.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158347_k127_588820_0	272123.Anacy_3007	1.261e-52	192.0	COG0625@1|root,COG0625@2|Bacteria,1G1XI@1117|Cyanobacteria	1117|Cyanobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_N,GST_N_3
SRR25158347_k127_588820_1	880073.Calab_1584	2.378e-40	156.0	COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158347_k127_589345_0	102129.Lepto7375DRAFT_1367	1.566e-05	56.0	COG2319@1|root,COG2319@2|Bacteria,1GBDU@1117|Cyanobacteria	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158347_k127_589658_0	1033810.HLPCO_002133	3.58e-43	173.0	COG1816@1|root,COG1816@2|Bacteria,2NR0J@2323|unclassified Bacteria	2|Bacteria	F	Adenosine/AMP deaminase	CP_0600	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158347_k127_59358_1	293613.A1E_04970	4.221e-18	86.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,47F10@766|Rickettsiales	766|Rickettsiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158347_k127_59358_0	522306.CAP2UW1_2498	6.286e-84	284.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria	1224|Proteobacteria	I	Dehydratase	MA20_00775	-	4.2.1.148,4.2.1.56	ko:K14449,ko:K18290	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R02491,R05076	RC00730,RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
SRR25158347_k127_595378_0	929556.Solca_2618	1.361e-47	177.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,1IYDB@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158347_k127_597578_1	1201288.M900_0553	1.378e-52	196.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2MTDK@213481|Bdellovibrionales,2WVSN@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
SRR25158347_k127_597578_0	313603.FB2170_15718	1.532e-129	424.0	COG0642@1|root,COG2205@2|Bacteria,4NG6V@976|Bacteroidetes,1HWTT@117743|Flavobacteriia,2PGGW@252356|Maribacter	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Response_reg
SRR25158347_k127_601735_0	1345695.CLSA_c42070	2.078e-20	99.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,36GR6@31979|Clostridiaceae	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
SRR25158347_k127_602857_1	3880.AET02848	4.14e-07	58.0	COG0666@1|root,KOG4177@2759|Eukaryota,37HIC@33090|Viridiplantae,3GDBX@35493|Streptophyta,4JSN2@91835|fabids	35493|Streptophyta	M	ankyrin repeat	-	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_3,Ank_4,Motile_Sperm
SRR25158347_k127_602857_0	2340.JV46_21110	7.03e-16	83.0	COG3422@1|root,COG3422@2|Bacteria,1N0S6@1224|Proteobacteria,1S8R7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	double-strand break repair	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
SRR25158347_k127_603796_1	485913.Krac_1060	6.083e-24	107.0	COG0789@1|root,COG0789@2|Bacteria,2G9AM@200795|Chloroflexi	200795|Chloroflexi	K	Transcription regulator MerR DNA binding	-	-	-	ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158347_k127_603796_0	1304885.AUEY01000012_gene1807	5.717e-47	179.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158347_k127_609830_1	1045858.Bint_2522	8.517e-21	95.0	COG0203@1|root,COG0203@2|Bacteria,2J841@203691|Spirochaetes	203691|Spirochaetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158347_k127_609830_0	573413.Spirs_0980	2.362e-94	319.0	COG0202@1|root,COG0202@2|Bacteria,2J58K@203691|Spirochaetes	203691|Spirochaetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158347_k127_609830_2	1195236.CTER_2769	3.677e-08	55.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158347_k127_609922_1	1304885.AUEY01000004_gene920	1.548e-11	65.0	COG2267@1|root,COG2267@2|Bacteria,1REM6@1224|Proteobacteria,42VM4@68525|delta/epsilon subdivisions,2WRYC@28221|Deltaproteobacteria,2MPNW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158347_k127_609922_0	1047013.AQSP01000092_gene315	1.095e-191	616.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158347_k127_609934_0	1122201.AUAZ01000004_gene3425	1.709e-50	194.0	COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,1RZZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	peptidase	JD73_18850	-	-	ko:K21511	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_S49
SRR25158347_k127_611501_0	686340.Metal_2975	1.671e-195	622.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XDNE@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158347_k127_620495_0	886882.PPSC2_p0287	1.657e-22	102.0	2DTGR@1|root,33K9H@2|Bacteria,1VNSI@1239|Firmicutes,4I261@91061|Bacilli,26YXC@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_620845_2	395493.BegalDRAFT_2271	2.844e-26	110.0	COG0451@1|root,COG0451@2|Bacteria,1RBIE@1224|Proteobacteria,1RTWH@1236|Gammaproteobacteria,4630B@72273|Thiotrichales	72273|Thiotrichales	GM	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.339	ko:K19180	ko00523,ko01130,map00523,map01130	-	R10190	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158347_k127_620845_1	56110.Oscil6304_0536	1.134e-71	245.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158347_k127_620845_0	1123248.KB893329_gene4456	1.206e-164	526.0	COG0500@1|root,COG0500@2|Bacteria,4PPPH@976|Bacteroidetes,1IW2X@117747|Sphingobacteriia	976|Bacteroidetes	Q	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158347_k127_620845_3	395494.Galf_2849	2.486e-16	81.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,2VI84@28216|Betaproteobacteria,44W8J@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158347_k127_62150_1	762948.HMPREF0733_11443	6.639e-43	161.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,1W7NW@1268|Micrococcaceae	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158347_k127_62150_0	1122605.KB893637_gene3093	9.267e-79	270.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,1IP0A@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158347_k127_623186_0	351627.Csac_2570	8.02e-35	145.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_627268_1	1201290.M902_1967	6.119e-09	68.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2MUNY@213481|Bdellovibrionales,2WKG2@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	PFAM sigma-54 factor interaction domain-containing protein	flbD	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158347_k127_627268_0	633147.Olsu_0001	1.543e-50	188.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CUR3@84998|Coriobacteriia	84998|Coriobacteriia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_633022_2	1382304.JNIL01000001_gene2826	0.0007801	47.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4HIUG@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158347_k127_633022_1	1179778.PMM47T1_00735	0.0001442	49.0	2E7KC@1|root,3322E@2|Bacteria,1NBFM@1224|Proteobacteria,1SDU2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_633022_0	385682.AFSL01000009_gene2468	6.317e-94	312.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia,3XJA1@558415|Marinilabiliaceae	976|Bacteroidetes	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158347_k127_635988_0	1009370.ALO_11099	9.888e-39	152.0	COG3755@1|root,COG3755@2|Bacteria	2|Bacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
SRR25158347_k127_635988_1	153721.MYP_4899	3.468e-38	147.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,47M24@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acetyl-CoA hydrolase transferase	cat2	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158347_k127_636655_0	1122947.FR7_1540	1.469e-40	156.0	COG1706@1|root,COG1706@2|Bacteria,1U2PI@1239|Firmicutes,4H258@909932|Negativicutes	909932|Negativicutes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
SRR25158347_k127_636780_0	273068.TTE1653	3.255e-62	225.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,42EWY@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158347_k127_636780_1	1209989.TepiRe1_1236	1.03e-37	153.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,42ETI@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_640124_1	1333998.M2A_0880	3.874e-30	123.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
SRR25158347_k127_640124_0	1254432.SCE1572_13460	4.763e-47	179.0	COG3687@1|root,COG3687@2|Bacteria,1R4HJ@1224|Proteobacteria,437ZS@68525|delta/epsilon subdivisions,2X9TG@28221|Deltaproteobacteria,2YV0P@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
SRR25158347_k127_643271_0	1232410.KI421418_gene2374	1.604e-148	482.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,42M05@68525|delta/epsilon subdivisions,2WKR9@28221|Deltaproteobacteria,43W0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158347_k127_647160_0	469604.HMPREF0946_01460	1.422e-20	105.0	COG0658@1|root,COG0658@2|Bacteria,378SE@32066|Fusobacteria	32066|Fusobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
SRR25158347_k127_647756_1	163908.KB235896_gene2522	3.481e-18	92.0	COG0286@1|root,COG0286@2|Bacteria,1G119@1117|Cyanobacteria,1HKJ8@1161|Nostocales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158347_k127_647756_0	877414.ATWA01000006_gene120	3.512e-39	152.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,267RN@186813|unclassified Clostridiales	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158347_k127_648618_0	1267211.KI669560_gene1967	1.646e-199	638.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158347_k127_65263_0	760192.Halhy_0385	4.198e-86	299.0	COG1131@1|root,COG1131@2|Bacteria,4NFJD@976|Bacteroidetes,1IXTV@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158347_k127_653313_0	1123248.KB893341_gene839	2.518e-34	153.0	COG3386@1|root,COG5295@1|root,COG3386@2|Bacteria,COG5295@2|Bacteria,4NMCF@976|Bacteroidetes,1IWGC@117747|Sphingobacteriia	2|Bacteria	UW	Domain of unknown function (DUF5122) beta-propeller	yeeJ	-	-	ko:K14274,ko:K21449	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
SRR25158347_k127_654998_0	1250278.JQNQ01000001_gene2981	3.158e-92	312.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158347_k127_654998_1	313612.L8106_18562	2.992e-57	203.0	COG2940@1|root,COG2940@2|Bacteria,1G6XB@1117|Cyanobacteria,1HCEZ@1150|Oscillatoriales	1117|Cyanobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
SRR25158347_k127_654998_2	1210884.HG799462_gene8667	3.887e-23	100.0	COG0110@1|root,COG1020@1|root,COG0110@2|Bacteria,COG1020@2|Bacteria,2IZDX@203682|Planctomycetes	203682|Planctomycetes	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
SRR25158347_k127_658524_0	35841.BT1A1_3292	5.885e-06	53.0	COG5464@1|root,COG5464@2|Bacteria,1TWKK@1239|Firmicutes	1239|Firmicutes	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SRR25158347_k127_661516_0	706587.Desti_3568	1.146e-15	85.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1MXJQ@1224|Proteobacteria,42RQT@68525|delta/epsilon subdivisions,2WPRU@28221|Deltaproteobacteria,2MS8B@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
SRR25158347_k127_664076_1	317619.ANKN01000075_gene3468	2.747e-12	70.0	COG0369@1|root,COG0369@2|Bacteria,1FZZF@1117|Cyanobacteria,1MM4B@1212|Prochloraceae	1117|Cyanobacteria	P	Alternative locus ID	petH	GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464	1.18.1.2	ko:K02641	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194,ko01000	-	-	iJN678.petH	CpcD,FAD_binding_6,NAD_binding_1
SRR25158347_k127_664076_3	660470.Theba_1223	2.032e-05	49.0	2DRG3@1|root,33BJS@2|Bacteria	2|Bacteria	S	Transcriptional Coactivator p15 (PC4)	-	-	-	-	-	-	-	-	-	-	-	-	PC4
SRR25158347_k127_664076_0	404380.Gbem_3019	1.888e-113	379.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,43U89@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158347_k127_664076_2	441769.ABFU01000037_gene179	7.68e-06	53.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus	91061|Bacilli	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
SRR25158347_k127_664247_0	1165096.ARWF01000001_gene153	7.643e-23	108.0	COG1388@1|root,COG4254@1|root,COG1388@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,2KN17@206350|Nitrosomonadales	206350|Nitrosomonadales	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158347_k127_664824_0	272123.Anacy_4208	5.008e-134	434.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1HM34@1161|Nostocales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158347_k127_664824_1	387093.SUN_1857	1.232e-93	326.0	COG0784@1|root,COG2202@1|root,COG3287@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3287@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2YTEC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Two-component sensor histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Response_reg
SRR25158347_k127_670779_0	1265505.ATUG01000001_gene3492	1.054e-95	331.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG4936@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHWA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
SRR25158347_k127_671074_0	329726.AM1_1733	1.829e-43	164.0	COG0502@1|root,COG0502@2|Bacteria,1G3B8@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.bioB	BATS,Radical_SAM
SRR25158347_k127_671074_1	755732.Fluta_3133	2.006e-13	79.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia,2PAYN@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_671232_0	247490.KSU1_B0314	5.303e-78	267.0	COG0449@1|root,COG0449@2|Bacteria,2IXF9@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158347_k127_671232_2	1168034.FH5T_18720	6.835e-29	122.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,2FTNR@200643|Bacteroidia	976|Bacteroidetes	K	antitermination factor	-	-	-	-	-	-	-	-	-	-	-	-	NusG
SRR25158347_k127_671232_1	580332.Slit_2904	9.61e-30	123.0	COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,2VV7T@28216|Betaproteobacteria,44WI6@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158347_k127_671399_0	697281.Mahau_0798	2.272e-135	441.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158347_k127_672454_0	744872.Spica_0285	3.277e-47	174.0	COG1373@1|root,COG1373@2|Bacteria,2J9II@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158347_k127_672454_1	997884.HMPREF1068_04041	7.658e-10	61.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,2FQYH@200643|Bacteroidia,4AT9F@815|Bacteroidaceae	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_675805_0	997346.HMPREF9374_3529	9.776e-57	207.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,27B3Q@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR25158347_k127_67654_0	572479.Hprae_0549	0.0001907	54.0	COG3144@1|root,COG3144@2|Bacteria,1V8J5@1239|Firmicutes	1239|Firmicutes	N	PFAM Flagellar hook-length control protein-like, C-terminal domain	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
SRR25158347_k127_676644_0	856793.MICA_1691	2.024e-149	480.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,4BPBY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158347_k127_676644_1	517418.Ctha_2277	4.878e-15	79.0	COG0002@1|root,COG0002@2|Bacteria,1FDE1@1090|Chlorobi	1090|Chlorobi	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158347_k127_677048_0	614083.AWQR01000023_gene151	2.529e-100	332.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_677048_1	114615.BRADO5175	4.474e-45	175.0	COG2227@1|root,COG2227@2|Bacteria,1R7ZA@1224|Proteobacteria,2U2FV@28211|Alphaproteobacteria,3JRTB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158347_k127_677849_0	56110.Oscil6304_4527	3.972e-158	514.0	COG0745@1|root,COG2114@1|root,COG4252@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG4252@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158347_k127_677849_1	118166.JH976537_gene382	8.283e-13	71.0	COG3287@1|root,COG3287@2|Bacteria,1G0HF@1117|Cyanobacteria,1H8G8@1150|Oscillatoriales	1117|Cyanobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158347_k127_678355_1	1278309.KB907100_gene2238	0.0005764	50.0	COG3489@1|root,COG3489@2|Bacteria,1MWBW@1224|Proteobacteria,1S2FI@1236|Gammaproteobacteria,1XJGA@135619|Oceanospirillales	135619|Oceanospirillales	S	Imelysin	-	-	-	ko:K07338	-	-	-	-	ko00000	-	-	-	Peptidase_M75
SRR25158347_k127_678355_0	1123057.P872_24845	6.402e-110	379.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158347_k127_681199_5	388413.ALPR1_08068	8.002e-06	54.0	COG0388@1|root,COG0388@2|Bacteria,4NH5P@976|Bacteroidetes,47RIC@768503|Cytophagia	976|Bacteroidetes	S	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158347_k127_681199_2	530564.Psta_4489	2.709e-44	163.0	COG0347@1|root,COG0347@2|Bacteria,2IZZN@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
SRR25158347_k127_681199_4	536233.CLO_2923	2.651e-11	68.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,36KNM@31979|Clostridiaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
SRR25158347_k127_681199_3	234267.Acid_4172	6.925e-39	150.0	COG3615@1|root,COG3615@2|Bacteria	2|Bacteria	P	Tellurite resistance protein tehB	tehB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.265	ko:K03647,ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	DUF1971,TehB
SRR25158347_k127_681199_1	96561.Dole_2007	9.748e-104	347.0	COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,42MGW@68525|delta/epsilon subdivisions,2WJQ1@28221|Deltaproteobacteria,2MHWM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
SRR25158347_k127_681199_0	1304885.AUEY01000010_gene1638	1.57e-131	424.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MJMW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_681755_0	237368.SCABRO_02185	7.321e-75	262.0	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
SRR25158347_k127_681755_1	56780.SYN_00029	5.653e-34	137.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MRYF@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158347_k127_683053_1	877418.ATWV01000017_gene1285	2.924e-45	176.0	COG0539@1|root,COG0539@2|Bacteria,2J5FY@203691|Spirochaetes	203691|Spirochaetes	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158347_k127_683053_2	1317122.ATO12_14365	8.831e-06	58.0	COG1228@1|root,COG4538@1|root,COG1228@2|Bacteria,COG4538@2|Bacteria,4NGGD@976|Bacteroidetes,1I07B@117743|Flavobacteriia,2YK3X@290174|Aquimarina	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
SRR25158347_k127_683053_0	375286.mma_2280	3.418e-123	403.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,473V6@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	wlbC	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158347_k127_684189_0	1131269.AQVV01000011_gene2538	1.579e-183	584.0	COG1004@1|root,COG1004@2|Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158347_k127_684189_1	671143.DAMO_0938	2.553e-147	472.0	COG2605@1|root,COG2605@2|Bacteria,2NP6Q@2323|unclassified Bacteria	2|Bacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158347_k127_686085_0	153721.MYP_1718	1.422e-92	315.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes	976|Bacteroidetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158347_k127_686567_0	1242864.D187_009072	1.561e-67	245.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2YY14@29|Myxococcales	28221|Deltaproteobacteria	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
SRR25158347_k127_68775_0	493475.GARC_1025	6.084e-20	100.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria,468QZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158347_k127_68854_0	1254432.SCE1572_19630	2.883e-40	166.0	COG0515@1|root,COG0643@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0643@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1MWXQ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,HAMP,HATPase_c,Hpt
SRR25158347_k127_688578_0	502025.Hoch_4497	3.372e-57	211.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,42R5A@68525|delta/epsilon subdivisions,2WN5N@28221|Deltaproteobacteria,2YUW3@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	catA	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
SRR25158347_k127_688578_1	1121033.AUCF01000011_gene1747	5.382e-14	78.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,2TSZG@28211|Alphaproteobacteria,2JPUJ@204441|Rhodospirillales	204441|Rhodospirillales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158347_k127_688920_1	314607.KB13_882	2.763e-37	153.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,1KPNX@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158347_k127_688920_0	555079.Toce_0953	6.861e-72	258.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,42ERF@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158347_k127_689752_0	529818.AMSG_08967T0	2.816e-24	117.0	COG0664@1|root,KOG0614@2759|Eukaryota	2759|Eukaryota	T	cGMP-dependent protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	RGS,cNMP_binding
SRR25158347_k127_689863_0	313612.L8106_04089	6.41e-60	219.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158347_k127_69080_1	1121012.AUKX01000035_gene815	7.333e-09	65.0	COG3012@1|root,COG4783@1|root,COG3012@2|Bacteria,COG4783@2|Bacteria,4NR0R@976|Bacteroidetes,1I1VF@117743|Flavobacteriia	976|Bacteroidetes	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF1186,SEC-C
SRR25158347_k127_69080_0	1278307.KB907037_gene653	1.081e-18	95.0	COG4976@1|root,COG4976@2|Bacteria,1QWSE@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158347_k127_692973_0	1123376.AUIU01000016_gene283	4.601e-15	78.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
SRR25158347_k127_694261_0	1450694.BTS2_3923	5.213e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,1VCHT@1239|Firmicutes,4HX1M@91061|Bacilli,1ZH9M@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_694914_0	279714.FuraDRAFT_1826	1.352e-72	259.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KPBX@206351|Neisseriales	206351|Neisseriales	M	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158347_k127_694914_1	573370.DMR_26570	5.111e-09	62.0	COG2845@1|root,COG2845@2|Bacteria,1R115@1224|Proteobacteria,43D52@68525|delta/epsilon subdivisions,2X8BQ@28221|Deltaproteobacteria,2MAK9@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
SRR25158347_k127_697507_0	667014.Thein_0169	2.342e-70	257.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GHCT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
SRR25158347_k127_697727_1	1347392.CCEZ01000014_gene2702	1.151e-14	84.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158347_k127_697727_0	545243.BAEV01000137_gene37	7.858e-23	103.0	COG1762@1|root,COG1762@2|Bacteria,1VA2N@1239|Firmicutes,24N94@186801|Clostridia,36IDA@31979|Clostridiaceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
SRR25158347_k127_704068_0	1282876.BAOK01000001_gene1657	0.0001196	53.0	COG2207@1|root,COG2207@2|Bacteria,1NIX9@1224|Proteobacteria,2V7JF@28211|Alphaproteobacteria,4BSVK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158347_k127_704428_0	463191.SSEG_03884	1.437e-24	105.0	COG5113@1|root,COG3236@2|Bacteria,2HQRT@201174|Actinobacteria	201174|Actinobacteria	O	protein conserved in bacteria	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
SRR25158347_k127_706461_0	1430440.MGMSRv2_2918	1.561e-36	153.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2JQ05@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0643 Chemotaxis protein histidine kinase and related kinases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_709284_0	927677.ALVU02000001_gene4167	5.218e-40	155.0	COG2199@1|root,COG3706@2|Bacteria,1GBM2@1117|Cyanobacteria	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
SRR25158347_k127_709284_1	1392490.JHZX01000001_gene3058	6.711e-24	109.0	COG2197@1|root,COG2197@2|Bacteria,4NF5P@976|Bacteroidetes,1IINV@117743|Flavobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158347_k127_709846_0	1173029.JH980292_gene1978	9.113e-37	152.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158347_k127_713386_0	1097668.BYI23_E000260	6.527e-12	76.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,2VMUW@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_714020_0	759914.BP951000_0387	8.287e-77	269.0	COG0442@1|root,COG0442@2|Bacteria,2J5HF@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158347_k127_714658_0	471854.Dfer_1387	1.485e-07	63.0	COG2755@1|root,COG2755@2|Bacteria,4PAZ7@976|Bacteroidetes,47UVP@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_715186_0	945713.IALB_2061	8.816e-13	81.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_715287_2	667014.Thein_1879	1.446e-23	105.0	COG0781@1|root,COG0781@2|Bacteria,2GHUU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158347_k127_715287_0	1121129.KB903359_gene2464	1.676e-59	209.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,2FNGS@200643|Bacteroidia,22XPW@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158347_k127_715287_1	56110.Oscil6304_2714	1.64e-28	129.0	COG4191@1|root,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR25158347_k127_715619_0	1328313.DS2_09372	5.673e-51	194.0	COG1106@1|root,COG1106@2|Bacteria,1MVU0@1224|Proteobacteria,1RQDI@1236|Gammaproteobacteria,4687D@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
SRR25158347_k127_716847_2	882.DVU_0337	0.0004623	46.0	2EB9N@1|root,335A6@2|Bacteria,1NSFM@1224|Proteobacteria,42YSS@68525|delta/epsilon subdivisions,2WUB3@28221|Deltaproteobacteria,2MAKG@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_716847_1	537972.ABQU01000028_gene507	3.327e-44	170.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2YNZT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158347_k127_716847_0	1353529.M899_1435	3.205e-114	374.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,43CWK@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.384	ko:K13327	ko00523,ko01130,map00523,map01130	M00801,M00802	R05526	RC00897	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158347_k127_717014_0	1304284.L21TH_1045	1.184e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1V3PA@1239|Firmicutes,24HAV@186801|Clostridia,36K2Q@31979|Clostridiaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158347_k127_717014_1	351627.Csac_0743	2.539e-23	108.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,42J77@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158347_k127_717718_1	5145.XP_001907707.1	1.658e-10	73.0	KOG0271@1|root,KOG0272@1|root,KOG0271@2759|Eukaryota,KOG0272@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q43U@4751|Fungi,3RM8R@4890|Ascomycota,21RIB@147550|Sordariomycetes,3UF1P@5139|Sordariales	4751|Fungi	A	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,WD40
SRR25158347_k127_717718_0	754477.Q7C_2606	8.509e-41	160.0	COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,1S2UX@1236|Gammaproteobacteria,462KI@72273|Thiotrichales	72273|Thiotrichales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_717948_1	1007103.AFHW01000025_gene338	7.79e-43	162.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158347_k127_717948_2	469596.HMPREF9488_01945	1.293e-17	89.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,3VQIB@526524|Erysipelotrichia	526524|Erysipelotrichia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_10,MafB19-deam
SRR25158347_k127_717948_0	224324.aq_1855	2.34e-87	306.0	COG2812@1|root,COG2812@2|Bacteria,2G3JE@200783|Aquificae	200783|Aquificae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158347_k127_717948_3	1121413.JMKT01000009_gene2179	1.742e-15	80.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2MCHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158347_k127_717948_4	526218.Sterm_1719	1.405e-05	48.0	COG0353@1|root,COG0353@2|Bacteria,378GZ@32066|Fusobacteria	32066|Fusobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158347_k127_718968_2	755732.Fluta_0732	7.774e-05	45.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,1I6W9@117743|Flavobacteriia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_718968_1	1499684.CCNP01000025_gene3729	4.022e-12	77.0	COG1434@1|root,COG1434@2|Bacteria,1VC9H@1239|Firmicutes,24A7Q@186801|Clostridia,36DW9@31979|Clostridiaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158347_k127_718968_0	1453505.JASY01000001_gene3280	3.911e-13	80.0	COG0438@1|root,COG0438@2|Bacteria,4NJDH@976|Bacteroidetes,1IIW0@117743|Flavobacteriia,2P0GM@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158347_k127_722273_0	243275.TDE_2279	4.966e-22	105.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_722603_0	518766.Rmar_0052	9.471e-09	64.0	2CKSA@1|root,2ZC1U@2|Bacteria,4NMGH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_724298_0	1121890.AUDO01000009_gene60	2.92e-61	217.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia,2NSHX@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158347_k127_724298_1	1185876.BN8_06294	4.414e-27	114.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,47Q47@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158347_k127_72460_0	1547445.LO80_05410	4.241e-27	116.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,45ZWG@72273|Thiotrichales	72273|Thiotrichales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,HemN_C,Radical_SAM
SRR25158347_k127_725126_1	887062.HGR_03587	7.354e-110	364.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria,4AJWS@80864|Comamonadaceae	28216|Betaproteobacteria	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158347_k127_725126_0	290397.Adeh_3916	1.819e-110	362.0	COG0842@1|root,COG0842@2|Bacteria,1R3XD@1224|Proteobacteria	1224|Proteobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158347_k127_725126_2	765420.OSCT_1526	9.022e-14	79.0	COG2085@1|root,COG2085@2|Bacteria,2G900@200795|Chloroflexi,37616@32061|Chloroflexia	32061|Chloroflexia	C	NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158347_k127_725619_0	926692.AZYG01000019_gene249	1.023e-254	801.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WACS@53433|Halanaerobiales	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158347_k127_725619_2	536232.CLM_3304	8.083e-06	57.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,24J9S@186801|Clostridia,36IYQ@31979|Clostridiaceae	186801|Clostridia	T	GAF domain	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
SRR25158347_k127_725619_1	667014.Thein_1047	5.909e-28	126.0	COG3604@1|root,COG3604@2|Bacteria,2GIAW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
SRR25158347_k127_725721_0	1408422.JHYF01000009_gene1999	1.413e-55	206.0	COG3635@1|root,COG3635@2|Bacteria,1UIDA@1239|Firmicutes,25EIA@186801|Clostridia	186801|Clostridia	G	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
SRR25158347_k127_725721_1	1127673.GLIP_4006	3.279e-45	166.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,1SB3Z@1236|Gammaproteobacteria,468JQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158347_k127_726222_1	391625.PPSIR1_12793	2.845e-32	145.0	COG1262@1|root,COG1262@2|Bacteria,1QA4V@1224|Proteobacteria,43DXT@68525|delta/epsilon subdivisions,2WZ5G@28221|Deltaproteobacteria,2Z1DE@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_726222_2	1131269.AQVV01000007_gene1029	1.034e-28	134.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_726222_0	1237149.C900_03150	2.521e-72	249.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158347_k127_726981_1	1121931.AUHG01000018_gene1356	3.145e-71	243.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,1I275@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158347_k127_726981_0	1121931.AUHG01000018_gene1357	3.251e-77	261.0	COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,1I3B4@117743|Flavobacteriia	976|Bacteroidetes	S	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158347_k127_726981_2	411154.GFO_0330	1.076e-67	230.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158347_k127_730996_2	373994.Riv7116_3785	1.345e-26	110.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1HRN7@1161|Nostocales	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158347_k127_730996_0	1499967.BAYZ01000122_gene3364	7.221e-140	452.0	COG0059@1|root,COG0059@2|Bacteria,2NNKS@2323|unclassified Bacteria	2|Bacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iJN746.PP_4678,iLJ478.TM0550	IlvC,IlvN
SRR25158347_k127_730996_1	1231057.AMGD01000024_gene2972	2.51e-62	216.0	COG3420@1|root,COG4733@1|root,COG5492@1|root,COG3420@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1V237@1239|Firmicutes	1239|Firmicutes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
SRR25158347_k127_734813_0	1384057.CD33_06000	3.336e-27	119.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,3IWUJ@400634|Lysinibacillus	91061|Bacilli	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158347_k127_734818_1	44060.JODL01000020_gene4864	6.143e-67	240.0	COG0332@1|root,COG0332@2|Bacteria,2IAK7@201174|Actinobacteria	201174|Actinobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158347_k127_734818_0	756067.MicvaDRAFT_5226	2.977e-109	366.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
SRR25158347_k127_735670_0	1174528.JH992893_gene5951	3.447e-86	310.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
SRR25158347_k127_736270_0	1317122.ATO12_11905	2.278e-162	518.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,1HXRG@117743|Flavobacteriia,2YI0N@290174|Aquimarina	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158347_k127_736270_1	1492737.FEM08_09730	4.399e-15	76.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia,2NVUC@237|Flavobacterium	976|Bacteroidetes	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
SRR25158347_k127_738370_1	546275.FUSPEROL_01848	8.996e-10	67.0	COG0747@1|root,COG0747@2|Bacteria,378WT@32066|Fusobacteria	32066|Fusobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158347_k127_738370_0	247634.GPB2148_479	1.007e-90	304.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1J4GG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158347_k127_744491_0	768671.ThimaDRAFT_0740	2.328e-70	249.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,1T4CS@1236|Gammaproteobacteria,1WZQU@135613|Chromatiales	135613|Chromatiales	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158347_k127_745860_1	706587.Desti_3742	1.279e-50	196.0	28MN9@1|root,2ZAXV@2|Bacteria,1PPEY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_745860_0	5911.EAR84712	1.492e-76	273.0	COG4642@1|root,KOG0583@1|root,KOG0231@2759|Eukaryota,KOG0583@2759|Eukaryota	2759|Eukaryota	G	protein serine/threonine kinase activity	-	-	-	ko:K20178	ko04138,map04138	-	-	-	ko00000,ko00001,ko04131	-	-	-	MORN,Pkinase
SRR25158347_k127_749133_0	314724.BT0552	3.463e-56	203.0	COG0272@1|root,COG0272@2|Bacteria,2J57Q@203691|Spirochaetes	203691|Spirochaetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158347_k127_749133_1	573064.Mefer_1462	4.253e-19	96.0	COG0565@1|root,arCOG01018@2157|Archaea,2XUIY@28890|Euryarchaeota,23QQD@183939|Methanococci	183939|Methanococci	J	TIGRFAM RNA methyltransferase, TrmH family, group 1	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158347_k127_749133_2	1173023.KE650771_gene4074	3.02e-06	52.0	COG1434@1|root,COG1434@2|Bacteria,1GBDS@1117|Cyanobacteria	1117|Cyanobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158347_k127_749540_1	1410609.JHVB01000001_gene2296	0.0004005	51.0	COG2208@1|root,COG2208@2|Bacteria,2J6MB@203691|Spirochaetes	203691|Spirochaetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	7TMR-DISM_7TM,SpoIIE
SRR25158347_k127_749540_0	1121447.JONL01000001_gene783	1.48e-19	91.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158347_k127_75131_0	518766.Rmar_2648	7.148e-115	377.0	COG4664@1|root,COG4664@2|Bacteria,4PM5T@976|Bacteroidetes,1FIK6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158347_k127_755249_0	596324.TREVI0001_1985	2.463e-24	118.0	COG2373@1|root,COG2373@2|Bacteria,2J5M0@203691|Spirochaetes	203691|Spirochaetes	S	Alpha-2-macroglobulin family	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Big_5,MG1
SRR25158347_k127_758973_0	1128398.Curi_c08120	9.335e-153	505.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,26ATH@186813|unclassified Clostridiales	186801|Clostridia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158347_k127_763857_0	1122135.KB893146_gene1554	1.518e-122	396.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	yghU	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
SRR25158347_k127_763857_4	67257.JODR01000006_gene2592	3.243e-05	50.0	COG3315@1|root,COG3315@2|Bacteria,2GN89@201174|Actinobacteria	201174|Actinobacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SRR25158347_k127_763857_1	661367.LLO_2139	4.346e-48	176.0	COG1846@1|root,COG1846@2|Bacteria,1MZEJ@1224|Proteobacteria,1SY96@1236|Gammaproteobacteria,1JEP8@118969|Legionellales	118969|Legionellales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158347_k127_763857_2	395494.Galf_0055	3.235e-20	95.0	COG5562@1|root,COG5562@2|Bacteria,1N9UF@1224|Proteobacteria,2W3SZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	phage envelope protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
SRR25158347_k127_763857_3	1434325.AZQN01000008_gene2875	2.461e-15	76.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,47QHI@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158347_k127_765953_1	1237149.C900_00386	4.773e-13	82.0	COG2852@1|root,COG2852@2|Bacteria,4NUSE@976|Bacteroidetes,47R33@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158347_k127_765953_0	933262.AXAM01000001_gene377	3.288e-233	735.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42Q2X@68525|delta/epsilon subdivisions,2WNQB@28221|Deltaproteobacteria,2MMA7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158347_k127_769181_0	1045858.Bint_1894	2.553e-31	139.0	COG0666@1|root,COG0666@2|Bacteria,2J5FX@203691|Spirochaetes	203691|Spirochaetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
SRR25158347_k127_779884_1	526218.Sterm_2028	6.885e-43	169.0	COG1663@1|root,COG1663@2|Bacteria,378S2@32066|Fusobacteria	32066|Fusobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158347_k127_779884_0	1237149.C900_02070	4.391e-51	186.0	COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158347_k127_781117_0	130081.XP_005708284.1	4.065e-106	351.0	COG0111@1|root,KOG0068@2759|Eukaryota	2759|Eukaryota	EH	phosphoglycerate dehydrogenase activity	SER33	GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0061759,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158347_k127_781117_1	1121439.dsat_0260	1.693e-07	59.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2X2GQ@28221|Deltaproteobacteria,2MC2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158347_k127_78117_0	309800.C498_13519	1.598e-54	206.0	COG0604@1|root,arCOG01458@2157|Archaea,2XU74@28890|Euryarchaeota,23T36@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor2	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158347_k127_78221_3	655811.HMPREF0078_0142	5.622e-05	48.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,22HW8@1570339|Peptoniphilaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158347_k127_78221_2	471875.RUMLAC_02560	3.166e-20	92.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158347_k127_78221_0	459349.CLOAM1130	1.917e-46	171.0	COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158347_k127_78221_1	1511.CLOST_2187	1.482e-22	101.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25RQU@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158347_k127_78386_0	868595.Desca_0175	1.362e-272	862.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158347_k127_78386_1	1121405.dsmv_3766	6.102e-22	95.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,42N4T@68525|delta/epsilon subdivisions,2WJK8@28221|Deltaproteobacteria,2MIQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
SRR25158347_k127_785289_0	309807.SRU_1520	6.095e-67	239.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1FJ41@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158347_k127_785289_2	1123325.JHUV01000008_gene526	1.098e-23	105.0	COG0319@1|root,COG0319@2|Bacteria,2G5AR@200783|Aquificae	200783|Aquificae	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158347_k127_785289_1	1278306.KB906907_gene86	4.358e-38	156.0	COG0744@1|root,COG0744@2|Bacteria,379FN@32066|Fusobacteria	32066|Fusobacteria	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158347_k127_787166_1	272123.Anacy_0054	2.551e-56	201.0	COG0196@1|root,COG3172@1|root,COG0196@2|Bacteria,COG3172@2|Bacteria,1G79P@1117|Cyanobacteria,1HPNK@1161|Nostocales	1117|Cyanobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR25158347_k127_787166_2	1408445.JHXP01000014_gene1406	3.519e-08	64.0	COG0666@1|root,COG0666@2|Bacteria,1QR46@1224|Proteobacteria,1T6ZT@1236|Gammaproteobacteria,1JEKZ@118969|Legionellales	118969|Legionellales	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2
SRR25158347_k127_787166_0	395493.BegalDRAFT_1750	9.697e-223	699.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,461RZ@72273|Thiotrichales	72273|Thiotrichales	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
SRR25158347_k127_787315_0	1184267.A11Q_2134	3.388e-141	466.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4308T@68525|delta/epsilon subdivisions,2MTI3@213481|Bdellovibrionales,2X727@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
SRR25158347_k127_787643_0	1501391.LG35_08335	1.388e-36	149.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,2FSDE@200643|Bacteroidia,22U7X@171550|Rikenellaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158347_k127_787643_1	41431.PCC8801_3510	0.0001658	50.0	2BPTN@1|root,32IM2@2|Bacteria,1GIP6@1117|Cyanobacteria,3KK8N@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4279
SRR25158347_k127_787768_0	96561.Dole_2977	9.085e-148	481.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,42Q61@68525|delta/epsilon subdivisions,2WM4W@28221|Deltaproteobacteria,2MJEU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158347_k127_790051_0	404589.Anae109_2071	5.312e-07	63.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_791191_1	268407.PWYN_25220	1.743e-17	95.0	COG0840@1|root,COG0840@2|Bacteria,1UVY9@1239|Firmicutes,4HB1T@91061|Bacilli,26SVW@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR25158347_k127_791191_0	639282.DEFDS_1803	4.783e-97	333.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2GESM@200930|Deferribacteres	200930|Deferribacteres	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158347_k127_791342_0	1234664.AMRO01000035_gene2724	3.954e-77	272.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1WEMS@129337|Geobacillus	91061|Bacilli	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158347_k127_791342_1	203122.Sde_0783	2.257e-32	135.0	COG0457@1|root,COG0457@2|Bacteria,1QW4E@1224|Proteobacteria,1SFXK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR25158347_k127_791342_2	903818.KI912268_gene1689	9.944e-06	49.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158347_k127_793479_1	936375.HMPREF1152_1565	3.295e-23	104.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WCXG@538999|Clostridiales incertae sedis	186801|Clostridia	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158347_k127_793479_0	1173023.KE650771_gene13	3.629e-60	212.0	COG0454@1|root,COG0456@2|Bacteria,1G5VH@1117|Cyanobacteria,1JH1E@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158347_k127_794646_0	1036674.A28LD_0200	6.253e-196	626.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,2QFBP@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158347_k127_795903_0	1173024.KI912151_gene2356	1.693e-247	809.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,1JHAR@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_796528_1	96561.Dole_2521	5.66e-11	74.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,42MXD@68525|delta/epsilon subdivisions,2WKDU@28221|Deltaproteobacteria,2MMMY@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2,SNARE_assoc
SRR25158347_k127_796528_0	1144342.PMI40_04247	1.962e-12	70.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VQ9I@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158347_k127_798208_0	1232437.KL662013_gene1341	5.943e-12	71.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158347_k127_800289_2	1250278.JQNQ01000001_gene420	3.913e-22	108.0	COG4870@1|root,COG4870@2|Bacteria,4NS9R@976|Bacteroidetes,1I0EV@117743|Flavobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_C1
SRR25158347_k127_800289_0	929556.Solca_4105	9.199e-121	399.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IPCH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
SRR25158347_k127_800289_1	1157490.EL26_12090	3.059e-30	123.0	COG2114@1|root,COG2114@2|Bacteria,1V8X9@1239|Firmicutes,4IQCE@91061|Bacilli	91061|Bacilli	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158347_k127_801962_0	621372.ACIH01000015_gene3932	2.024e-98	334.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158347_k127_801962_1	1289135.A966_02961	1.16e-14	76.0	COG0750@1|root,COG0750@2|Bacteria,2J616@203691|Spirochaetes	203691|Spirochaetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158347_k127_802400_0	290512.Paes_1402	8.978e-58	216.0	COG0841@1|root,COG0841@2|Bacteria,1FEYE@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_803271_0	889378.Spiaf_2815	5.555e-69	249.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	3D,Glucosaminidase,OapA,Peptidase_M23
SRR25158347_k127_804165_0	1009370.ALO_13619	2.004e-52	195.0	COG3786@1|root,COG3786@2|Bacteria,1VA00@1239|Firmicutes,4H5FT@909932|Negativicutes	909932|Negativicutes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158347_k127_804165_1	690850.Desaf_3069	4.471e-49	184.0	COG2173@1|root,COG2173@2|Bacteria,1N3QY@1224|Proteobacteria,42TQ8@68525|delta/epsilon subdivisions,2WNK8@28221|Deltaproteobacteria,2M9YV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158347_k127_805360_0	944547.ABLL_1646	1.062e-53	206.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GGDEF,NMT1,SBP_bac_3
SRR25158347_k127_806379_0	1268303.RHODMAR_2546	1.093e-42	168.0	COG1018@1|root,COG1018@2|Bacteria,2GJSW@201174|Actinobacteria,4FVZM@85025|Nocardiaceae	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158347_k127_808591_0	714943.Mucpa_4458	8.131e-139	462.0	COG0288@1|root,COG0659@1|root,COG0288@2|Bacteria,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
SRR25158347_k127_808591_1	1449050.JNLE01000003_gene259	1.623e-24	111.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia,36DCI@31979|Clostridiaceae	186801|Clostridia	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
SRR25158347_k127_814234_0	862908.BMS_0881	2.427e-55	203.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2WITT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158347_k127_814234_1	349124.Hhal_1886	3.128e-07	61.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_817314_0	1123274.KB899435_gene1313	8.898e-43	175.0	COG2604@1|root,COG2604@2|Bacteria,2J5P0@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
SRR25158347_k127_817314_1	237368.SCABRO_00684	2.076e-21	101.0	COG5551@1|root,COG5551@2|Bacteria,2J1TK@203682|Planctomycetes	203682|Planctomycetes	S	CRISPR-associated endoribonuclease Cas6	-	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
SRR25158347_k127_817644_2	313628.LNTAR_08919	1.472e-05	55.0	COG1076@1|root,COG1076@2|Bacteria	2|Bacteria	O	ATPase activator activity	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
SRR25158347_k127_817644_0	555088.DealDRAFT_1706	2.911e-116	384.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,42JQF@68298|Syntrophomonadaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158347_k127_817644_1	706587.Desti_4507	1.267e-24	108.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,42THT@68525|delta/epsilon subdivisions,2X5YE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158347_k127_823251_0	1380370.JIBA01000010_gene2409	4.37e-29	123.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4FGX0@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158347_k127_823251_1	1307436.PBF_19888	6.846e-13	74.0	COG4454@1|root,COG4454@2|Bacteria,1V23W@1239|Firmicutes,4HGGT@91061|Bacilli,1ZEGR@1386|Bacillus	91061|Bacilli	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158347_k127_824089_0	197221.22294503	2.112e-78	267.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158347_k127_824089_1	153948.NAL212_0606	1.781e-24	111.0	COG0457@1|root,COG0457@2|Bacteria,1PWF6@1224|Proteobacteria,2WBZP@28216|Betaproteobacteria,3742M@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
SRR25158347_k127_824741_0	10228.TriadP32769	2.806e-23	108.0	COG1011@1|root,KOG3085@2759|Eukaryota,38CID@33154|Opisthokonta,3BJEU@33208|Metazoa	33208|Metazoa	S	hydrolase activity	HDHD3	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR25158347_k127_824741_1	269799.Gmet_3275	7.273e-11	68.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PHB@68525|delta/epsilon subdivisions,2WMJX@28221|Deltaproteobacteria,43S0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,KOW
SRR25158347_k127_825297_0	694427.Palpr_1315	1.22e-91	306.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,2FM7V@200643|Bacteroidia,22X0R@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
SRR25158347_k127_826142_0	545694.TREPR_2339	1.301e-37	147.0	COG0539@1|root,COG0539@2|Bacteria,2J5DZ@203691|Spirochaetes	203691|Spirochaetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Cytidylate_kin,S1
SRR25158347_k127_826975_0	118168.MC7420_1221	8.542e-52	190.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1H7T7@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158347_k127_826975_1	933262.AXAM01000049_gene3278	3.481e-33	130.0	COG1672@1|root,COG1672@2|Bacteria,1N4VD@1224|Proteobacteria,42Y71@68525|delta/epsilon subdivisions,2WTK1@28221|Deltaproteobacteria,2MMHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
SRR25158347_k127_827496_1	383372.Rcas_0511	1.081e-22	101.0	COG3695@1|root,COG3695@2|Bacteria,2G7CY@200795|Chloroflexi,37621@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
SRR25158347_k127_827496_0	1266845.Q783_00100	6.915e-60	216.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,27FBD@186828|Carnobacteriaceae	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158347_k127_828727_0	1129794.C427_1133	4.498e-255	795.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,465IW@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158347_k127_829767_2	3067.XP_002949211.1	7.327e-05	51.0	KOG0498@1|root,KOG0498@2759|Eukaryota	2759|Eukaryota	U	voltage-gated potassium channel activity	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans,cNMP_binding
SRR25158347_k127_829767_0	313628.LNTAR_24551	1.038e-116	386.0	COG4260@1|root,COG4260@2|Bacteria	2|Bacteria	N	virion core protein, lumpy skin disease virus	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339
SRR25158347_k127_829767_1	390989.JOEG01000001_gene5376	9.491e-09	58.0	COG1996@1|root,COG1996@2|Bacteria,2GZE0@201174|Actinobacteria,4D99D@85008|Micromonosporales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_832655_0	684949.ATTJ01000001_gene843	1.215e-09	68.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
SRR25158347_k127_832655_1	1121957.ATVL01000006_gene2982	2.489e-07	60.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158347_k127_832993_0	335543.Sfum_2352	1.931e-126	422.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MQI5@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158347_k127_832993_1	931626.Awo_c15210	2.406e-39	153.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25UR7@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158347_k127_834905_0	118168.MC7420_5421	7.704e-13	81.0	COG2114@1|root,COG2202@1|root,COG3437@1|root,COG2114@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,1GQRR@1117|Cyanobacteria,1H9GQ@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,PAS_9,Response_reg
SRR25158347_k127_837941_0	1121931.AUHG01000016_gene1046	1.281e-221	693.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
SRR25158347_k127_843781_0	502025.Hoch_6049	1.703e-66	234.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
SRR25158347_k127_843953_0	1237149.C900_04365	4.588e-23	111.0	COG1629@1|root,COG4771@2|Bacteria,4NM9G@976|Bacteroidetes,47UNA@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_844327_0	755731.Clo1100_1725	0.0006389	51.0	COG3391@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4733@2|Bacteria,1UEBB@1239|Firmicutes,24DIX@186801|Clostridia,36HNU@31979|Clostridiaceae	186801|Clostridia	N	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_8457_3	56110.Oscil6304_1719	0.0001754	45.0	COG2405@1|root,COG2405@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
SRR25158347_k127_8457_2	383372.Rcas_0409	2.322e-06	53.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
SRR25158347_k127_8457_0	324925.Ppha_0757	6.666e-27	112.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158347_k127_8457_1	457398.HMPREF0326_01332	6.417e-08	56.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,42X7S@68525|delta/epsilon subdivisions,2WSVH@28221|Deltaproteobacteria,2ME01@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158347_k127_854077_0	181119.XP_005520895.1	0.0003884	52.0	COG0457@1|root,KOG1124@2759|Eukaryota,39B55@33154|Opisthokonta,3BE34@33208|Metazoa,3CVF9@33213|Bilateria,485IB@7711|Chordata,4906T@7742|Vertebrata,4GR87@8782|Aves	33208|Metazoa	S	Interferon-induced protein with tetratricopeptide repeats	IFIT5	GO:0000049,GO:0000339,GO:0001726,GO:0002252,GO:0002376,GO:0002682,GO:0002683,GO:0002697,GO:0002698,GO:0002831,GO:0002832,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0006810,GO:0006886,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0008104,GO:0008150,GO:0008187,GO:0008266,GO:0009605,GO:0009607,GO:0009615,GO:0009617,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010646,GO:0010647,GO:0014070,GO:0015031,GO:0015629,GO:0015833,GO:0016020,GO:0019060,GO:0019221,GO:0023051,GO:0023052,GO:0023056,GO:0030581,GO:0031252,GO:0031253,GO:0031256,GO:0031347,GO:0031348,GO:0032091,GO:0032101,GO:0032102,GO:0032587,GO:0033036,GO:0034097,GO:0034340,GO:0034613,GO:0035455,GO:0035456,GO:0035457,GO:0035458,GO:0042221,GO:0042592,GO:0042886,GO:0042995,GO:0043086,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043330,GO:0043331,GO:0043393,GO:0043900,GO:0043901,GO:0043902,GO:0043903,GO:0044092,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044766,GO:0045069,GO:0045070,GO:0045071,GO:0045087,GO:0045177,GO:0045184,GO:0046719,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048524,GO:0048525,GO:0048583,GO:0048584,GO:0048585,GO:0048878,GO:0050687,GO:0050688,GO:0050689,GO:0050691,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050896,GO:0051095,GO:0051097,GO:0051098,GO:0051100,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051607,GO:0051641,GO:0051649,GO:0051701,GO:0051704,GO:0051707,GO:0051708,GO:0051716,GO:0060337,GO:0065007,GO:0065008,GO:0065009,GO:0070727,GO:0070887,GO:0071310,GO:0071345,GO:0071357,GO:0071359,GO:0071360,GO:0071407,GO:0071702,GO:0071705,GO:0071944,GO:0080134,GO:0097159,GO:0098542,GO:0098590,GO:0120025,GO:0120038,GO:1901363,GO:1901698,GO:1901699,GO:1902531,GO:1902533,GO:1902579,GO:1902581,GO:1902583,GO:1903900,GO:1903901,GO:1903902	-	ko:K14217	ko05160,ko05168,map05160,map05168	-	-	-	ko00000,ko00001	-	-	-	TPR_12,TPR_16,TPR_2,TPR_7,TPR_8
SRR25158347_k127_854137_0	1047013.AQSP01000092_gene315	7.597e-100	341.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158347_k127_857867_0	598659.NAMH_0970	3.946e-117	388.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BT1
SRR25158347_k127_858635_0	58123.JOFJ01000009_gene1046	8.675e-72	261.0	COG0330@1|root,COG0330@2|Bacteria,2IC5W@201174|Actinobacteria	201174|Actinobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158347_k127_858828_0	1415778.JQMM01000001_gene884	1.189e-10	72.0	COG3119@1|root,COG3119@2|Bacteria,1PESK@1224|Proteobacteria,1T9ZC@1236|Gammaproteobacteria,1J948@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_860907_0	1356854.N007_12985	2.285e-146	472.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,278UX@186823|Alicyclobacillaceae	91061|Bacilli	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158347_k127_862246_0	1353529.M899_0627	7.6e-75	259.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2MTNX@213481|Bdellovibrionales,2WN3P@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158347_k127_862246_1	1453501.JELR01000002_gene1302	1.407e-27	118.0	COG3108@1|root,COG3108@2|Bacteria,1N3XU@1224|Proteobacteria,1SQF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRR25158347_k127_86762_0	1254432.SCE1572_32910	3.146e-71	255.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2WJNS@28221|Deltaproteobacteria,2Z3JN@29|Myxococcales	28221|Deltaproteobacteria	KLT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,Pkinase
SRR25158347_k127_86762_1	1254432.SCE1572_32915	1.309e-16	88.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,Response_reg
SRR25158347_k127_868505_0	714943.Mucpa_6158	3.111e-22	101.0	COG0824@1|root,COG0824@2|Bacteria,4NQ3I@976|Bacteroidetes,1ITE5@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158347_k127_868505_1	1173028.ANKO01000130_gene1882	1.087e-13	77.0	COG4276@1|root,COG4276@2|Bacteria,1G60I@1117|Cyanobacteria,1HBA1@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158347_k127_871195_2	1552123.EP57_14850	4.202e-36	147.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,26J7D@186820|Listeriaceae	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR25158347_k127_871195_0	247634.GPB2148_1992	5.052e-116	381.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1J5QW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158347_k127_871195_1	1082931.KKY_1567	1.386e-49	179.0	COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria,2U95P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158347_k127_87413_0	1242864.D187_009204	7.449e-143	465.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2YTU2@29|Myxococcales	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158347_k127_87413_1	1174528.JH992898_gene5145	5.892e-09	62.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GD97@1117|Cyanobacteria,1JHAR@1189|Stigonemataceae	1117|Cyanobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
SRR25158347_k127_874242_0	1304888.ATWF01000001_gene1276	2.062e-64	226.0	COG0004@1|root,COG0004@2|Bacteria,2GER5@200930|Deferribacteres	2|Bacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,EAL,GGDEF,HATPase_c,HisKA,HisKA_3,MCPsignal,PAS_9,Response_reg
SRR25158347_k127_874242_1	1499967.BAYZ01000089_gene5053	1.14e-06	54.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158347_k127_875966_0	243275.TDE_1352	3.555e-22	106.0	COG0768@1|root,COG0768@2|Bacteria,2J595@203691|Spirochaetes	203691|Spirochaetes	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158347_k127_875966_1	754027.HMPREF9554_02060	1.692e-06	56.0	COG2891@1|root,COG2891@2|Bacteria,2J89Q@203691|Spirochaetes	203691|Spirochaetes	M	Rod shape-determining protein (MreD)	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158347_k127_879848_1	237727.NAP1_15563	1.063e-31	125.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2U7G8@28211|Alphaproteobacteria,2K456@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158347_k127_879848_0	273075.Ta1123	7.142e-33	138.0	COG0579@1|root,arCOG00754@2157|Archaea,2Y8CD@28890|Euryarchaeota	28890|Euryarchaeota	C	Dehydrogenase	-	-	1.1.5.3	ko:K00111,ko:K15736	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	BON,DAO,Fer2_BFD
SRR25158347_k127_881217_0	756067.MicvaDRAFT_3583	3.719e-136	451.0	COG0515@1|root,COG0642@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
SRR25158347_k127_882770_1	224308.BSU31420	0.000189	51.0	COG2267@1|root,COG2267@2|Bacteria,1TP59@1239|Firmicutes,4HEFN@91061|Bacilli,1ZBTQ@1386|Bacillus	91061|Bacilli	I	Hydrolase	yugF	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158347_k127_882770_0	1265505.ATUG01000002_gene2058	0.0001162	50.0	COG1639@1|root,COG1639@2|Bacteria,1R737@1224|Proteobacteria,42P64@68525|delta/epsilon subdivisions,2WMDJ@28221|Deltaproteobacteria,2MHMK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
SRR25158347_k127_883505_1	1297742.A176_02373	2.82e-11	76.0	COG2984@1|root,COG2984@2|Bacteria,1Q1HG@1224|Proteobacteria,4379R@68525|delta/epsilon subdivisions,2X2DR@28221|Deltaproteobacteria,2YZ7R@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158347_k127_883505_0	87626.PTD2_12954	2.848e-26	119.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RS27@1236|Gammaproteobacteria,2Q1GN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG4771 Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
SRR25158347_k127_883530_0	379066.GAU_0820	8.573e-113	383.0	COG1138@1|root,COG1138@2|Bacteria,1ZTBY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158347_k127_885606_0	1227500.C494_20178	2.893e-78	273.0	arCOG01405@1|root,arCOG01405@2157|Archaea	2157|Archaea	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158347_k127_885973_0	1122947.FR7_4087	1.462e-166	529.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,4H2XK@909932|Negativicutes	909932|Negativicutes	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
SRR25158347_k127_886671_0	43989.cce_2186	2.837e-09	70.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1FZVW@1117|Cyanobacteria,3KH8A@43988|Cyanothece	1117|Cyanobacteria	L	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SRR25158347_k127_886734_0	1049564.TevJSym_ad00970	2.222e-134	438.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1J4JP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
SRR25158347_k127_886734_1	192952.MM_2204	1.823e-22	96.0	COG0610@1|root,arCOG00878@2157|Archaea,2XSZ2@28890|Euryarchaeota,2N95V@224756|Methanomicrobia	224756|Methanomicrobia	V	Domain of unknown function (DUF3387)	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
SRR25158347_k127_895112_2	90814.KL370891_gene273	1.748e-24	113.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,461XM@72273|Thiotrichales	72273|Thiotrichales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
SRR25158347_k127_895112_0	1191523.MROS_1575	1.653e-87	304.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH,SGL
SRR25158347_k127_895112_1	1499967.BAYZ01000177_gene5744	4.385e-58	223.0	COG1368@1|root,COG1368@2|Bacteria,2NRZV@2323|unclassified Bacteria	2|Bacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158347_k127_895336_0	679937.Bcop_0207	1.426e-92	319.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia,4AMJG@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
SRR25158347_k127_895336_1	744872.Spica_1401	5.459e-20	95.0	COG0537@1|root,COG0537@2|Bacteria,2JAFV@203691|Spirochaetes	203691|Spirochaetes	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158347_k127_895503_0	1353529.M899_0650	6.255e-177	586.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158347_k127_896876_2	765869.BDW_12790	5.335e-43	161.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2MSM3@213481|Bdellovibrionales,2WMB0@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158347_k127_896876_1	118005.AWNK01000007_gene711	2.045e-90	306.0	COG0548@1|root,COG0548@2|Bacteria	2|Bacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565,iJN678.argB,iLJ478.TM1784	AA_kinase
SRR25158347_k127_896876_0	123214.PERMA_0406	4.896e-97	322.0	COG0339@1|root,COG0339@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158347_k127_897524_0	459349.CLOAM1516	6.466e-35	147.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRR25158347_k127_89910_0	1173029.JH980292_gene2348	3.102e-175	564.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
SRR25158347_k127_899641_0	1121930.AQXG01000002_gene2285	1.854e-64	226.0	COG0471@1|root,COG0471@2|Bacteria,4PIFM@976|Bacteroidetes,1ITUY@117747|Sphingobacteriia	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
SRR25158347_k127_905164_1	1122225.AULQ01000004_gene2050	7.113e-48	174.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia	976|Bacteroidetes	S	Flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158347_k127_905164_0	909663.KI867149_gene3351	4.862e-79	279.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2MQGW@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
SRR25158347_k127_905488_1	397287.C807_03464	9.26e-07	55.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,27I7K@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_905488_0	1274402.JQAJ01000002_gene578	1.696e-23	107.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,47EZ6@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158347_k127_905761_1	305900.GV64_22300	1.468e-22	102.0	28MN9@1|root,2ZAXV@2|Bacteria,1PPEY@1224|Proteobacteria,1RYAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_905761_0	1385511.N783_06810	1.244e-26	119.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,2Y8YX@289201|Pontibacillus	91061|Bacilli	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158347_k127_905761_2	1121373.KB903663_gene1100	2.026e-14	78.0	COG1974@1|root,COG1974@2|Bacteria,4NQXK@976|Bacteroidetes,47R6P@768503|Cytophagia	976|Bacteroidetes	KT	Peptidase S24-like	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158347_k127_906035_0	882083.SacmaDRAFT_1972	3.324e-56	219.0	COG0553@1|root,COG0553@2|Bacteria,2GM2V@201174|Actinobacteria,4DXMJ@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM helicase	-	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	DUF3883,Helicase_C,SNF2_N
SRR25158347_k127_907901_0	313624.NSP_37540	2.167e-26	116.0	COG2885@1|root,COG2885@2|Bacteria,1G58H@1117|Cyanobacteria,1HRMH@1161|Nostocales	1117|Cyanobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158347_k127_908943_0	387093.SUN_0861	6.339e-141	456.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2YPEH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158347_k127_908951_1	1121887.AUDK01000002_gene2152	0.0009318	47.0	COG4251@1|root,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,1I3JF@117743|Flavobacteriia,2P0F3@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158347_k127_908951_0	933115.GPDM_13066	4.156e-81	277.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,26D6Q@186818|Planococcaceae	91061|Bacilli	L	Endonuclease/Exonuclease/phosphatase family	exoA	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158347_k127_91123_2	179408.Osc7112_4578	3.861e-33	132.0	COG3146@1|root,COG3146@2|Bacteria,1G0U8@1117|Cyanobacteria,1H7FC@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG3146 conserved	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
SRR25158347_k127_91123_0	1121904.ARBP01000026_gene619	5.569e-153	497.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,47KSE@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158347_k127_91123_1	1159488.SEQMU2_05570	1.032e-40	159.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,4GWXZ@90964|Staphylococcaceae	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158347_k127_914793_1	1220534.B655_1281	1.525e-07	54.0	COG1366@1|root,arCOG06891@2157|Archaea,2Y4H8@28890|Euryarchaeota	28890|Euryarchaeota	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158347_k127_914793_0	1158338.JNLJ01000005_gene1766	5.096e-55	202.0	COG0134@1|root,COG0134@2|Bacteria,2G3YD@200783|Aquificae	200783|Aquificae	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158347_k127_915277_1	639282.DEFDS_P148	0.0004131	46.0	COG1406@1|root,COG1406@2|Bacteria,2GFNF@200930|Deferribacteres	200930|Deferribacteres	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
SRR25158347_k127_915277_0	755178.Cyan10605_1494	6.198e-06	55.0	COG5350@1|root,COG5350@2|Bacteria,1G4AH@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DSPc,HEAT_2,HEAT_PBS
SRR25158347_k127_916898_0	1379281.AVAG01000033_gene464	4.128e-65	229.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2M8J7@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158347_k127_917913_0	1415775.U729_3017	1.357e-51	190.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,36EH5@31979|Clostridiaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158347_k127_917913_1	479431.Namu_3164	2.613e-37	146.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4ESAD@85013|Frankiales	201174|Actinobacteria	H	PFAM Quinolinate phosphoribosyl transferase	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158347_k127_92036_0	756272.Plabr_2317	2.49e-35	150.0	COG2208@1|root,COG2208@2|Bacteria,2IYKI@203682|Planctomycetes	203682|Planctomycetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
SRR25158347_k127_922684_1	871963.Desdi_0449	2.607e-23	102.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,261TV@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158347_k127_922684_2	269799.Gmet_0639	3.402e-22	96.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,43VH4@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158347_k127_922684_0	1329516.JPST01000015_gene706	4.564e-70	241.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,27B66@186824|Thermoactinomycetaceae	91061|Bacilli	J	ribosomal L5P family C-terminus	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158347_k127_926949_0	449447.MAE_33400	7.477e-66	239.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,PAS_9,Pkinase,Response_reg
SRR25158347_k127_928999_0	1173027.Mic7113_3377	7.871e-147	488.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1H9WN@1150|Oscillatoriales	1117|Cyanobacteria	T	7TM diverse intracellular signalling	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
SRR25158347_k127_929652_6	313606.M23134_04574	0.0008195	42.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia	976|Bacteroidetes	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
SRR25158347_k127_929652_4	313606.M23134_06670	1.616e-15	78.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
SRR25158347_k127_929652_1	1121012.AUKX01000010_gene2007	3.535e-119	390.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1HXAJ@117743|Flavobacteriia,23I2Z@178469|Arenibacter	976|Bacteroidetes	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
SRR25158347_k127_929652_0	688270.Celal_2114	3.635e-146	467.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia,1FA74@104264|Cellulophaga	976|Bacteroidetes	HJ	COGs COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
SRR25158347_k127_929652_3	1250005.PHEL85_1194	1.391e-40	155.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,1I2N1@117743|Flavobacteriia,3VWKH@52959|Polaribacter	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
SRR25158347_k127_929652_5	221288.JH992901_gene4759	2.71e-11	66.0	COG3791@1|root,COG3791@2|Bacteria,1G9JF@1117|Cyanobacteria,1JM2B@1189|Stigonemataceae	1117|Cyanobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158347_k127_929652_2	866536.Belba_2923	1.241e-66	243.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,47KXY@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158347_k127_929956_1	448385.sce4409	4.924e-09	65.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2YUDK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
SRR25158347_k127_929956_0	1047013.AQSP01000123_gene1546	2.108e-28	127.0	COG4953@1|root,COG4953@2|Bacteria,2NQMA@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
SRR25158347_k127_933346_0	1168289.AJKI01000002_gene2684	1.398e-68	237.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,2G0ES@200643|Bacteroidia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158347_k127_933346_1	5762.XP_002672598.1	3.646e-20	93.0	COG5272@1|root,KOG0001@2759|Eukaryota	2759|Eukaryota	O	cellular macromolecule catabolic process	-	-	-	ko:K02977,ko:K08770	ko03010,ko03320,map03010,map03320	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121,ko04147	-	-	-	ubiquitin
SRR25158347_k127_934915_1	530564.Psta_2177	2.346e-19	93.0	COG0727@1|root,COG0727@2|Bacteria,2IZU5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158347_k127_934915_0	765869.BDW_07970	1.179e-77	269.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,42S7V@68525|delta/epsilon subdivisions,2MSV3@213481|Bdellovibrionales,2WNFD@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158347_k127_937860_1	933262.AXAM01000032_gene695	3.708e-12	74.0	COG1462@1|root,COG1462@2|Bacteria,1PUD4@1224|Proteobacteria,43530@68525|delta/epsilon subdivisions,2X94S@28221|Deltaproteobacteria,2MP2K@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
SRR25158347_k127_937860_0	862908.BMS_2276	3.458e-32	134.0	COG0500@1|root,COG0500@2|Bacteria,1R947@1224|Proteobacteria,432GY@68525|delta/epsilon subdivisions,2WYII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_944074_0	877418.ATWV01000001_gene1432	1.385e-30	139.0	COG2208@1|root,COG2208@2|Bacteria,2J6MB@203691|Spirochaetes	203691|Spirochaetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	7TMR-DISM_7TM,SpoIIE
SRR25158347_k127_946713_1	646529.Desaci_0142	0.000131	49.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,267C6@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158347_k127_946713_0	1123389.ATXJ01000001_gene867	4.345e-105	346.0	COG4663@1|root,COG4663@2|Bacteria,1WJ6R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
SRR25158347_k127_950151_0	1121904.ARBP01000012_gene1211	8.293e-180	572.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158347_k127_950151_1	102129.Lepto7375DRAFT_8399	5.725e-116	385.0	COG1454@1|root,COG1454@2|Bacteria,1G26Q@1117|Cyanobacteria	1117|Cyanobacteria	C	Alcohol dehydrogenase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158347_k127_950151_2	1276756.AUEX01000005_gene2709	6.11e-51	186.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,4AAN2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158347_k127_950725_0	425104.Ssed_3347	1.392e-205	649.0	COG1960@1|root,COG1960@2|Bacteria,1R15B@1224|Proteobacteria	1224|Proteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158347_k127_955490_0	247490.KSU1_C0412	1.627e-104	346.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158347_k127_955490_1	1122172.KB890271_gene285	9.545e-40	156.0	COG0317@1|root,COG0317@2|Bacteria,378FY@32066|Fusobacteria	32066|Fusobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158347_k127_956332_0	1121020.JIAG01000001_gene1214	1.004e-11	77.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae	201174|Actinobacteria	K	Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158347_k127_957409_0	641524.ADICYQ_2337	3.682e-59	210.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	cmoM	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360	-	ko:K06219,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPMT
SRR25158347_k127_958488_1	1415779.JOMH01000001_gene266	2.834e-38	147.0	COG4399@1|root,COG4399@2|Bacteria,1R404@1224|Proteobacteria,1S1H5@1236|Gammaproteobacteria,1X9DZ@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158347_k127_958488_0	1089553.Tph_c16880	7.843e-63	229.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,42G1M@68295|Thermoanaerobacterales	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158347_k127_958488_2	339860.Msp_0649	0.0002798	43.0	COG0139@1|root,arCOG02676@2157|Archaea,2XX3X@28890|Euryarchaeota,23P25@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158347_k127_95903_2	586413.CCDL010000001_gene1536	2.267e-08	61.0	COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAK1@91061|Bacilli,23MJ1@182709|Oceanobacillus	91061|Bacilli	T	Putative diguanylate phosphodiesterase	M1-600	-	-	-	-	-	-	-	-	-	-	-	EAL
SRR25158347_k127_95903_0	215803.DB30_3645	5.583e-132	436.0	COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,42Z7G@68525|delta/epsilon subdivisions,2WU0D@28221|Deltaproteobacteria,2YU48@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158347_k127_95903_1	452471.Aasi_1435	2.806e-57	216.0	COG0666@1|root,COG1196@1|root,COG0666@2|Bacteria,COG1196@2|Bacteria,4NEYY@976|Bacteroidetes,47MVD@768503|Cytophagia	976|Bacteroidetes	U	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,SHOCT,SecA_DEAD
SRR25158347_k127_959631_0	211165.AJLN01000047_gene6208	2.252e-25	107.0	COG2886@1|root,COG2886@2|Bacteria,1GEP1@1117|Cyanobacteria,1JM85@1189|Stigonemataceae	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
SRR25158347_k127_959631_1	929562.Emtol_1960	5.859e-21	101.0	COG3950@1|root,COG3950@2|Bacteria,4NKIH@976|Bacteroidetes,47R3I@768503|Cytophagia	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
SRR25158347_k127_959920_0	1089550.ATTH01000001_gene2284	2.754e-63	238.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl
SRR25158347_k127_962331_1	1002809.SSIL_0838	3.344e-13	72.0	COG0645@1|root,COG0645@2|Bacteria,1UCU3@1239|Firmicutes,4HE7Y@91061|Bacilli,26H4C@186818|Planococcaceae	91061|Bacilli	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158347_k127_962331_0	1349767.GJA_322	1.472e-66	233.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,Response_reg
SRR25158347_k127_962753_1	1121033.AUCF01000009_gene1170	6.93e-29	120.0	COG3173@1|root,COG3173@2|Bacteria,1R5MY@1224|Proteobacteria,2U4NY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158347_k127_962753_0	614083.AWQR01000023_gene152	1.26e-127	409.0	COG0500@1|root,COG2226@2|Bacteria,1QSZ6@1224|Proteobacteria,2WF44@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_963295_0	1304880.JAGB01000005_gene2448	5.541e-91	306.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158347_k127_963295_1	592026.GCWU0000282_001365	5.197e-60	214.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158347_k127_965417_2	1034807.FBFL15_0362	3.968e-69	242.0	COG3386@1|root,COG3386@2|Bacteria,4PNAW@976|Bacteroidetes,1IK6R@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158347_k127_965417_3	1122951.ATUE01000006_gene865	3.72e-55	197.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,3NKT2@468|Moraxellaceae	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158347_k127_965417_1	1237149.C900_02752	8.036e-183	582.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,47NY5@768503|Cytophagia	976|Bacteroidetes	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158347_k127_965417_0	1237149.C900_02753	2.525e-207	654.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158347_k127_965417_4	1121875.KB907547_gene2916	2.061e-54	198.0	COG1335@1|root,COG2453@1|root,COG1335@2|Bacteria,COG2453@2|Bacteria,4NXZM@976|Bacteroidetes	976|Bacteroidetes	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
SRR25158347_k127_975280_1	485915.Dret_1035	1.381e-58	204.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2M7Y6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
SRR25158347_k127_975280_0	1443122.Z958_02620	5.453e-79	269.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,36EE0@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158347_k127_975713_0	1286631.X805_17410	0.0004492	51.0	2DYB8@1|root,32V54@2|Bacteria,1N0G4@1224|Proteobacteria,2VUAU@28216|Betaproteobacteria,1KNBV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_977269_1	471854.Dfer_1245	4.971e-49	185.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158347_k127_977269_0	1201290.M902_0847	9.387e-65	231.0	COG0628@1|root,COG0628@2|Bacteria,1PMAP@1224|Proteobacteria,4345I@68525|delta/epsilon subdivisions,2MTCT@213481|Bdellovibrionales,2X23B@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158347_k127_979289_0	313606.M23134_04250	1.215e-34	142.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,47KEU@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158347_k127_979289_1	1341181.FLJC2902T_06480	8.021e-26	113.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1IMIN@117743|Flavobacteriia,2NTWH@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158347_k127_979434_0	880070.Cycma_4829	1.183e-57	218.0	COG4251@1|root,COG4251@2|Bacteria,4NN2W@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
SRR25158347_k127_983646_0	1274374.CBLK010000070_gene1112	5.484e-133	434.0	COG0668@1|root,COG0668@2|Bacteria,1TSHU@1239|Firmicutes,4HBC1@91061|Bacilli,26T2D@186822|Paenibacillaceae	91061|Bacilli	M	Mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
SRR25158347_k127_989045_1	1207063.P24_00870	4.61e-29	117.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158347_k127_989045_0	1249627.D779_3956	5.137e-169	546.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria,1WWH7@135613|Chromatiales	135613|Chromatiales	HJ	ATP-grasp	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,RimK
SRR25158347_k127_989621_0	1266925.JHVX01000003_gene456	3.905e-38	156.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,371RC@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Aminotransferase, class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158347_k127_993379_0	264202.CF0132	1.102e-22	105.0	COG2265@1|root,COG2265@2|Bacteria,2JFX6@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	-	-	-	-	-	-	-	-	-	-	tRNA_U5-meth_tr
SRR25158347_k127_993716_1	1395587.P364_0113955	3.147e-07	60.0	COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,1UEBB@1239|Firmicutes,4HB9W@91061|Bacilli,26VDK@186822|Paenibacillaceae	91061|Bacilli	I	Fibronectin type 3 domain	Tnr	-	-	-	-	-	-	-	-	-	-	-	SLH,fn3
SRR25158347_k127_993716_0	1125863.JAFN01000001_gene796	3.709e-17	85.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158347_k127_993865_0	289377.HL41_02985	1.003e-74	271.0	COG0643@1|root,COG0643@2|Bacteria,2GH2Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158347_k127_996806_0	1125701.HMPREF1221_01161	5.474e-100	340.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,2J5GP@203691|Spirochaetes	203691|Spirochaetes	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
## 3305 queries scanned
## Total time (seconds): 35.700583934783936
## Rate: 92.58 q/s