## Thu Feb 19 01:05:11 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158348_bin.10.fa -m mmseqs --output SRR25158348_bin.10 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158348_bin.10 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158348_k127_1000274_0	32057.KB217478_gene1432	2.49e-78	291.0	COG0438@1|root,COG0438@2|Bacteria,1G32B@1117|Cyanobacteria,1HQ1N@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_1000274_2	404589.Anae109_3856	1.471e-06	62.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,42SUR@68525|delta/epsilon subdivisions,2WPNH@28221|Deltaproteobacteria,2Z2JJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158348_k127_1000274_1	489825.LYNGBM3L_22550	1.819e-45	182.0	COG2244@1|root,COG2244@2|Bacteria,1G2BA@1117|Cyanobacteria,1H8SP@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158348_k127_1001868_2	1121033.AUCF01000045_gene3987	1.178e-52	211.0	COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TXPT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK,PAS_10,PAS_4
SRR25158348_k127_1001868_5	309807.SRU_0678	2.117e-23	117.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
SRR25158348_k127_1001868_4	290397.Adeh_3192	2.549e-27	113.0	2AZF8@1|root,31RP4@2|Bacteria,1RIZG@1224|Proteobacteria,42ZVQ@68525|delta/epsilon subdivisions,2WV5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1001868_3	1172188.KB911824_gene3385	1.701e-41	162.0	2BVXR@1|root,32IG2@2|Bacteria,2IMT1@201174|Actinobacteria,4FGU2@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158348_k127_1001868_1	240015.ACP_2901	4.046e-59	214.0	COG0778@1|root,COG0778@2|Bacteria,3Y5RQ@57723|Acidobacteria,2JKAP@204432|Acidobacteriia	204432|Acidobacteriia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158348_k127_1001868_0	1254432.SCE1572_47320	3.631e-95	336.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42PS5@68525|delta/epsilon subdivisions,2X77E@28221|Deltaproteobacteria,2YUM9@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158348_k127_1001998_3	243233.MCA1000	7.482e-07	53.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
SRR25158348_k127_1001998_0	1341151.ASZU01000001_gene680	3.816e-88	310.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,27B0Z@186824|Thermoactinomycetaceae	91061|Bacilli	F	Glutamine amidotransferase domain	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
SRR25158348_k127_1001998_2	457429.ABJI02000279_gene3471	9.82e-14	72.0	COG4877@1|root,COG4877@2|Bacteria,2GQV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1001998_1	391625.PPSIR1_07693	6.339e-41	168.0	COG0863@1|root,COG0863@2|Bacteria,1NCJF@1224|Proteobacteria,42WGQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,UPF0020
SRR25158348_k127_1002639_1	582744.Msip34_2356	1.087e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,1MXNY@1224|Proteobacteria,2VN50@28216|Betaproteobacteria,2KN0I@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158348_k127_1002639_0	582899.Hden_0329	3.142e-101	340.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,3N8BX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055,ko:K19707	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Abhydrolase_1
SRR25158348_k127_1005713_0	1280694.AUJQ01000004_gene704	3.051e-88	300.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3NH38@46205|Pseudobutyrivibrio	186801|Clostridia	E	Phenazine biosynthesis-like protein	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158348_k127_1005713_2	1121930.AQXG01000005_gene712	2.55e-17	96.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
SRR25158348_k127_1005713_3	391037.Sare_0368	1.204e-14	87.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2IF2T@201174|Actinobacteria,4DBYG@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Kelch_1,Peptidase_S8
SRR25158348_k127_1005713_1	344747.PM8797T_07342	1.819e-22	106.0	COG1039@1|root,COG1039@2|Bacteria,2IZ83@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1012243_0	880073.Calab_1752	1.587e-115	377.0	COG1960@1|root,COG1960@2|Bacteria,2NQE6@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158348_k127_1012243_1	1123073.KB899241_gene2570	1.942e-109	368.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1X40U@135614|Xanthomonadales	135614|Xanthomonadales	J	Oxidoreductase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR25158348_k127_1012243_2	661478.OP10G_2718	6.274e-09	58.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	AXE1,DLH
SRR25158348_k127_1014246_1	573063.Metin_0484	3.867e-68	246.0	COG0464@1|root,arCOG01307@2157|Archaea,2XTNA@28890|Euryarchaeota,23RUB@183939|Methanococci	183939|Methanococci	D	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Vps4_C
SRR25158348_k127_1014246_4	195522.BD01_0727	1.345e-08	63.0	arCOG07402@1|root,arCOG07402@2157|Archaea,2Y300@28890|Euryarchaeota,242KQ@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1014246_2	5932.XP_004031986.1	3.138e-64	234.0	COG0464@1|root,KOG0730@2759|Eukaryota,3ZBHE@5878|Ciliophora	5878|Ciliophora	O	Cell division protein 48 (CDC48) N-terminal domain	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
SRR25158348_k127_1014246_3	497964.CfE428DRAFT_5644	1.181e-12	79.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,46UMD@74201|Verrucomicrobia	2|Bacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158348_k127_1014246_0	632518.Calow_1188	5.379e-173	565.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158348_k127_1016850_2	56780.SYN_02046	1.356e-51	186.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2MQ6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158348_k127_1016850_3	374847.Kcr_1486	1.279e-16	86.0	COG1371@1|root,arCOG04055@2157|Archaea	2157|Archaea	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158348_k127_1016850_1	1192034.CAP_4781	7.705e-136	449.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2YUFR@29|Myxococcales	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158348_k127_1016850_0	1121468.AUBR01000045_gene1800	8.83e-240	777.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,42FI5@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158348_k127_1016850_4	1121468.AUBR01000018_gene2702	1.476e-13	73.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158348_k127_1018780_0	1192034.CAP_8308	2.23e-41	160.0	COG3220@1|root,COG3220@2|Bacteria,1Q38G@1224|Proteobacteria,438ZE@68525|delta/epsilon subdivisions,2X44P@28221|Deltaproteobacteria,2YY8Z@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
SRR25158348_k127_1018780_1	997346.HMPREF9374_0080	1.123e-18	93.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,27B4Z@186824|Thermoactinomycetaceae	91061|Bacilli	O	Bacterial trigger factor protein (TF) C-terminus	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158348_k127_1028031_2	349521.HCH_02499	1.95e-69	247.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,1STV6@1236|Gammaproteobacteria,1XQTP@135619|Oceanospirillales	135619|Oceanospirillales	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SRR25158348_k127_1028031_4	1484479.DI14_01120	7.156e-08	64.0	COG1413@1|root,COG1413@2|Bacteria,1VG5Z@1239|Firmicutes,4HP2U@91061|Bacilli	91061|Bacilli	C	Scaffold protein Nfu NifU	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N
SRR25158348_k127_1028031_0	1120973.AQXL01000129_gene2455	1.466e-110	371.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,4HAGM@91061|Bacilli,27810@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
SRR25158348_k127_1028031_5	243090.RB9222	0.0001259	47.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXR8@203682|Planctomycetes	203682|Planctomycetes	MO	MucD-putative a secreted serine proteinase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
SRR25158348_k127_1028031_1	344747.PM8797T_14444	2.974e-72	256.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXR8@203682|Planctomycetes	203682|Planctomycetes	MO	MucD-putative a secreted serine proteinase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
SRR25158348_k127_1028031_3	1125863.JAFN01000001_gene2172	5.695e-13	70.0	COG3012@1|root,COG3012@2|Bacteria,1NBWN@1224|Proteobacteria,42ZV9@68525|delta/epsilon subdivisions,2WVCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1186)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1186,SEC-C
SRR25158348_k127_102966_0	886293.Sinac_6020	3.625e-311	975.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal
SRR25158348_k127_102966_3	886293.Sinac_6021	9.53e-73	249.0	COG2080@1|root,COG2080@2|Bacteria,2IZCW@203682|Planctomycetes	2|Bacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302,ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158348_k127_102966_2	530564.Psta_0806	3.185e-143	461.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158348_k127_102966_1	671143.DAMO_1619	3.098e-194	617.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158348_k127_1036052_1	521674.Plim_1459	1.441e-31	135.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
SRR25158348_k127_1036052_0	880072.Desac_2489	1.645e-92	313.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MR4I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158348_k127_1037740_1	745411.B3C1_08906	6.833e-11	74.0	COG3325@1|root,COG4412@1|root,COG3325@2|Bacteria,COG4412@2|Bacteria,1RKAD@1224|Proteobacteria,1S8JD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
SRR25158348_k127_1037740_2	391612.CY0110_28334	1.99e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G5UW@1117|Cyanobacteria,3KHBI@43988|Cyanothece	1117|Cyanobacteria	S	PFAM TPR repeat-containing protein	mom72	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158348_k127_1037740_0	661478.OP10G_4206	8.136e-62	242.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
SRR25158348_k127_1039923_0	383372.Rcas_0031	9.132e-102	353.0	COG2114@1|root,COG2114@2|Bacteria,2GBUH@200795|Chloroflexi,376W9@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158348_k127_1039923_1	1121440.AUMA01000008_gene853	2.589e-28	117.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2M82B@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
SRR25158348_k127_1040700_4	1173026.Glo7428_2204	1.04e-21	94.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158348_k127_1040700_3	292563.Cyast_1665	5.24e-22	110.0	COG0745@1|root,COG0745@2|Bacteria,1G11F@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_1040700_2	595460.RRSWK_02101	2.3e-52	203.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,WD40
SRR25158348_k127_1040700_1	439235.Dalk_0205	3.567e-65	245.0	28RRT@1|root,33K0J@2|Bacteria,1NKEP@1224|Proteobacteria,430T6@68525|delta/epsilon subdivisions,2WW1A@28221|Deltaproteobacteria,2MNQS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
SRR25158348_k127_1040700_5	684949.ATTJ01000001_gene2818	3.691e-06	60.0	COG0607@1|root,COG0607@2|Bacteria,1WKHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158348_k127_1040700_0	686340.Metal_2782	1.199e-118	398.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1XETH@135618|Methylococcales	135618|Methylococcales	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K18300	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17	-	-	OEP
SRR25158348_k127_1040828_2	243231.GSU2601	2.648e-10	72.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
SRR25158348_k127_1040828_1	204669.Acid345_0824	3.931e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JKYK@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158348_k127_1040828_0	392500.Swoo_1678	7.767e-26	115.0	COG1225@1|root,COG1225@2|Bacteria,1QZW6@1224|Proteobacteria,1T4AY@1236|Gammaproteobacteria,2QD3D@267890|Shewanellaceae	1236|Gammaproteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158348_k127_1041201_1	1304885.AUEY01000002_gene359	8.637e-75	258.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MJRC@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158348_k127_1041201_0	1304885.AUEY01000002_gene358	0.0	1298.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI2Z@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158348_k127_1041201_2	1304885.AUEY01000002_gene357	6.633e-46	173.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MJ5Q@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
SRR25158348_k127_1041229_0	1499967.BAYZ01000009_gene5335	2.489e-110	364.0	COG1690@1|root,COG1690@2|Bacteria,2NNVX@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the RtcB family	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158348_k127_1041229_1	237368.SCABRO_03194	2.429e-84	301.0	COG0240@1|root,COG0240@2|Bacteria,2IWWN@203682|Planctomycetes	203682|Planctomycetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158348_k127_1041229_2	1210884.HG799467_gene13404	3.119e-37	150.0	COG0344@1|root,COG0344@2|Bacteria,2J0DJ@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	DUF4149,G3P_acyltransf
SRR25158348_k127_10447_3	657309.BXY_38490	7.047e-06	59.0	28RJ8@1|root,2ZDY4@2|Bacteria,4NNAE@976|Bacteroidetes,2FQIM@200643|Bacteroidia,4APW6@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_10447_2	100226.SCO1731	5.034e-09	68.0	COG0500@1|root,COG0500@2|Bacteria,2GKYW@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4,Methyltransf_11,NUDIX
SRR25158348_k127_10447_1	582515.KR51_00026960	5.392e-43	165.0	COG1216@1|root,COG1216@2|Bacteria,1G0X3@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
SRR25158348_k127_10447_0	96561.Dole_2534	1.717e-184	607.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
SRR25158348_k127_104531_1	1267534.KB906756_gene561	1.942e-124	416.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158348_k127_104531_0	1191523.MROS_1555	5.661e-128	430.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158348_k127_104919_2	340177.Cag_0301	4.274e-39	162.0	COG0457@1|root,COG0859@1|root,COG1912@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,COG1912@2|Bacteria,1FDZ8@1090|Chlorobi	1090|Chlorobi	M	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158348_k127_104919_1	1499967.BAYZ01000095_gene4122	1.298e-53	206.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_104919_0	555088.DealDRAFT_1808	9.04e-69	243.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,42K5R@68298|Syntrophomonadaceae	186801|Clostridia	S	Peptidase M16	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158348_k127_1050457_1	192952.MM_1056	5.266e-38	155.0	COG1668@1|root,arCOG01462@2157|Archaea,2XX4X@28890|Euryarchaeota,2NAR7@224756|Methanomicrobia	224756|Methanomicrobia	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158348_k127_1050457_0	1123371.ATXH01000001_gene1300	1.501e-271	846.0	COG0458@1|root,COG0458@2|Bacteria,2GH37@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EF	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158348_k127_1063980_1	517418.Ctha_1405	1.407e-29	129.0	COG4591@1|root,COG4591@2|Bacteria,1FECJ@1090|Chlorobi	1090|Chlorobi	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158348_k127_1063980_2	309800.C498_11721	3.782e-26	121.0	COG1254@1|root,arCOG01674@2157|Archaea,2XYT5@28890|Euryarchaeota,23WSX@183963|Halobacteria	183963|Halobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158348_k127_1063980_3	1162668.LFE_1737	1.338e-11	68.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
SRR25158348_k127_1063980_0	234267.Acid_7925	6.924e-42	159.0	COG3832@1|root,COG3832@2|Bacteria,3Y94H@57723|Acidobacteria	57723|Acidobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1064005_1	298653.Franean1_3765	8.981e-10	69.0	COG5502@1|root,COG5502@2|Bacteria,2ISMP@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158348_k127_1064005_0	751945.Theos_1791	7.805e-13	79.0	COG5502@1|root,COG5502@2|Bacteria,1WJW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158348_k127_1064787_0	338966.Ppro_1304	1.029e-84	293.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158348_k127_1064787_1	479434.Sthe_1036	1.045e-29	121.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,27XVD@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158348_k127_1068492_1	632335.Calkr_1474	1.41e-78	272.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,42EPM@68295|Thermoanaerobacterales	186801|Clostridia	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158348_k127_1068492_7	1121364.ATVG01000008_gene519	0.0006041	51.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,22K21@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158348_k127_1068492_0	530564.Psta_3580	5.463e-127	419.0	COG2262@1|root,COG2262@2|Bacteria,2IXH5@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158348_k127_1068492_2	693661.Arcve_1599	8.038e-76	268.0	arCOG06187@1|root,arCOG06187@2157|Archaea,2XTSP@28890|Euryarchaeota,246YD@183980|Archaeoglobi	183980|Archaeoglobi	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	MreB_Mbl
SRR25158348_k127_1068492_3	693661.Arcve_1599	9e-72	265.0	arCOG06187@1|root,arCOG06187@2157|Archaea,2XTSP@28890|Euryarchaeota,246YD@183980|Archaeoglobi	183980|Archaeoglobi	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	MreB_Mbl
SRR25158348_k127_1068492_6	756272.Plabr_2990	2.384e-22	100.0	COG0640@1|root,COG0640@2|Bacteria,2J12M@203682|Planctomycetes	203682|Planctomycetes	K	transcriptional regulator, ArsR family protein	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158348_k127_1068492_4	1254432.SCE1572_04655	3.826e-63	224.0	COG0580@1|root,COG0580@2|Bacteria,1QAD6@1224|Proteobacteria,434QA@68525|delta/epsilon subdivisions,2WZ1M@28221|Deltaproteobacteria,2Z14G@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	-	-	-	-	-	-	-	-	-	MIP
SRR25158348_k127_1068492_5	483219.LILAB_30145	1.898e-45	181.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158348_k127_1069379_0	448385.sce2668	8.042e-62	244.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
SRR25158348_k127_1070760_0	452637.Oter_1803	3.942e-102	339.0	COG4263@1|root,COG4263@2|Bacteria,46YT5@74201|Verrucomicrobia,3K7SZ@414999|Opitutae	414999|Opitutae	C	Cupredoxin-like domain	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
SRR25158348_k127_1070760_1	1124780.ANNU01000013_gene3870	6.939e-21	101.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,47R42@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158348_k127_1071566_0	1120973.AQXL01000123_gene3043	1.786e-136	439.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,2781C@186823|Alicyclobacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158348_k127_1072497_0	290397.Adeh_2455	1.816e-93	324.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158348_k127_1072497_1	13333.ERN18389	1.46e-35	137.0	COG1089@1|root,KOG1372@2759|Eukaryota,37HE5@33090|Viridiplantae,3G75T@35493|Streptophyta	35493|Streptophyta	G	GDP-mannose 4,6 dehydratase	-	GO:0000902,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008446,GO:0009058,GO:0009225,GO:0009226,GO:0009653,GO:0009826,GO:0009987,GO:0016043,GO:0016049,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0032502,GO:0032989,GO:0034641,GO:0034654,GO:0040007,GO:0042350,GO:0042351,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046368,GO:0046483,GO:0048589,GO:0048856,GO:0048869,GO:0055086,GO:0060560,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158348_k127_1081792_4	391625.PPSIR1_39800	3.303e-10	64.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158348_k127_1081792_2	1210884.HG799466_gene12317	2.844e-74	267.0	29ZE1@1|root,30MD7@2|Bacteria,2J1UE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1081792_3	1463887.KL589984_gene3351	4.512e-24	110.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158348_k127_1081792_1	1150399.AQYK01000001_gene950	3.852e-90	311.0	COG0702@1|root,COG0702@2|Bacteria,2IQ0Z@201174|Actinobacteria,4FM9R@85023|Microbacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NAD_binding_10
SRR25158348_k127_1081792_5	1120953.AUBH01000004_gene2953	0.0002051	52.0	COG5592@1|root,COG5592@2|Bacteria,1QVT0@1224|Proteobacteria,1T8M7@1236|Gammaproteobacteria,469BB@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158348_k127_1081792_0	1144275.COCOR_06404	1.301e-127	415.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
SRR25158348_k127_108303_0	644966.Tmar_1638	9.098e-167	537.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158348_k127_108303_1	1250232.JQNJ01000001_gene1081	3.163e-23	115.0	COG0578@1|root,COG0578@2|Bacteria,4PKIZ@976|Bacteroidetes,1IJMF@117743|Flavobacteriia	976|Bacteroidetes	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158348_k127_1085277_2	1156937.MFUM_940033	3.504e-67	237.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia,37GGX@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158348_k127_1085277_4	268407.PWYN_00825	3.104e-31	135.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,26UNW@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158348_k127_1085277_7	443144.GM21_0601	7.401e-12	77.0	COG3156@1|root,COG3156@2|Bacteria,1N9I4@1224|Proteobacteria,42V0N@68525|delta/epsilon subdivisions,2WRR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
SRR25158348_k127_1085277_1	643562.Daes_1196	1.122e-70	249.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2M93E@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158348_k127_1085277_3	330214.NIDE2977	3.764e-49	184.0	COG1211@1|root,COG1211@2|Bacteria,3J18C@40117|Nitrospirae	40117|Nitrospirae	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158348_k127_1085277_5	530564.Psta_0077	5.855e-17	86.0	2DVHI@1|root,32UZG@2|Bacteria,2J0QY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SRR25158348_k127_1085277_0	247490.KSU1_D0789	5.56e-103	357.0	COG0771@1|root,COG0771@2|Bacteria,2IX53@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158348_k127_1085277_8	352165.HMPREF7215_1108	4.163e-05	55.0	COG0457@1|root,COG1462@1|root,COG0457@2|Bacteria,COG1462@2|Bacteria,3TB3V@508458|Synergistetes	508458|Synergistetes	M	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
SRR25158348_k127_1085277_6	756272.Plabr_4400	4.533e-16	79.0	COG0272@1|root,COG0272@2|Bacteria,2IXIC@203682|Planctomycetes	203682|Planctomycetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158348_k127_1090883_0	1038860.AXAP01000006_gene6684	9.645e-23	111.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2TRQQ@28211|Alphaproteobacteria,3JRHA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158348_k127_1094979_2	1303518.CCALI_02200	6.611e-53	189.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	mccB	-	2.1.3.15,6.4.1.3,6.4.1.4,6.4.1.5	ko:K01969,ko:K13778,ko:K15052	ko00280,ko00281,ko00720,ko01100,ko01200,map00280,map00281,map00720,map01100,map01200	M00036,M00376	R01859,R03494,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3290	Carboxyl_trans
SRR25158348_k127_1094979_1	479434.Sthe_1363	1.442e-57	211.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158348_k127_1094979_0	247490.KSU1_C0408	1.348e-294	934.0	COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158348_k127_1094979_6	521719.ATXQ01000010_gene21	2.144e-06	56.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1YDQP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
SRR25158348_k127_1094979_5	746697.Aeqsu_0662	2.188e-10	67.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
SRR25158348_k127_1094979_3	671143.DAMO_1385	1.297e-50	189.0	COG0731@1|root,COG0731@2|Bacteria,2NR61@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
SRR25158348_k127_1094979_4	391625.PPSIR1_27758	1.977e-39	149.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2YY6V@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate flavodoxin ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158348_k127_1095612_1	429009.Adeg_0304	4.011e-70	243.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158348_k127_1095612_0	1218076.BAYB01000032_gene5099	4.118e-217	684.0	COG0425@1|root,COG0620@1|root,COG0425@2|Bacteria,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2VKXM@28216|Betaproteobacteria,1KCGE@119060|Burkholderiaceae	28216|Betaproteobacteria	EO	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158348_k127_1095612_2	1034347.CAHJ01000044_gene4882	1.243e-28	115.0	COG2044@1|root,COG2044@2|Bacteria,1UA45@1239|Firmicutes,4IKDW@91061|Bacilli,1ZGNG@1386|Bacillus	91061|Bacilli	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158348_k127_1104239_1	530564.Psta_2521	1.789e-52	188.0	COG1327@1|root,COG1327@2|Bacteria,2IZQ3@203682|Planctomycetes	203682|Planctomycetes	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158348_k127_1104239_0	247490.KSU1_C0073	6.035e-90	318.0	COG1328@1|root,COG1328@2|Bacteria	2|Bacteria	F	CTP reductase activity	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
SRR25158348_k127_110722_1	247490.KSU1_C1202	0.0	1016.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158348_k127_110722_0	237368.SCABRO_01952	0.0	1497.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158348_k127_110722_2	1519464.HY22_03460	3.145e-31	129.0	COG0222@1|root,COG0222@2|Bacteria,1FE3H@1090|Chlorobi	1090|Chlorobi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158348_k127_1112701_4	518766.Rmar_0658	1.025e-06	60.0	COG3712@1|root,COG5662@1|root,COG3712@2|Bacteria,COG5662@2|Bacteria,4NREY@976|Bacteroidetes,1FJ7Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
SRR25158348_k127_1112701_5	1121428.DESHY_40085___1	5.643e-05	54.0	COG5662@1|root,COG5662@2|Bacteria,1U216@1239|Firmicutes,25N56@186801|Clostridia,2631J@186807|Peptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
SRR25158348_k127_1112701_3	521045.Kole_0421	1.111e-13	82.0	COG1409@1|root,COG1409@2|Bacteria,2GDWS@200918|Thermotogae	200918|Thermotogae	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158348_k127_1112701_0	452637.Oter_2033	2.214e-151	492.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
SRR25158348_k127_1116466_2	1128421.JAGA01000002_gene1557	7.35e-68	235.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158348_k127_1116466_0	234267.Acid_4069	1.182e-194	617.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158348_k127_1116466_5	247490.KSU1_C1551	2.743e-33	143.0	COG1376@1|root,COG1376@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
SRR25158348_k127_1116466_1	88036.EFJ08617	4.343e-87	314.0	COG0169@1|root,KOG0692@2759|Eukaryota,37I1M@33090|Viridiplantae,3GDN1@35493|Streptophyta	35493|Streptophyta	E	Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase	-	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SRR25158348_k127_1116466_7	1142394.PSMK_06260	9.865e-07	61.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SRR25158348_k127_1116466_6	278957.ABEA03000045_gene1253	6.366e-27	123.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U4F@74201|Verrucomicrobia,3K7AH@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
SRR25158348_k127_1116466_4	237368.SCABRO_03814	5.053e-36	149.0	COG0703@1|root,COG0703@2|Bacteria,2J038@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158348_k127_1116466_3	1500894.JQNN01000001_gene3644	1.409e-42	167.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,2VS2J@28216|Betaproteobacteria,472QF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158348_k127_1117387_3	670487.Ocepr_1393	7.812e-21	94.0	COG0082@1|root,COG0082@2|Bacteria,1WJ05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158348_k127_1117387_1	243231.GSU2260	2.711e-116	399.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,43U5R@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158348_k127_1117387_2	497964.CfE428DRAFT_4578	9.049e-23	107.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
SRR25158348_k127_1117387_0	555079.Toce_0684	9.519e-274	867.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158348_k127_1117387_4	234267.Acid_5820	6.359e-07	56.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158348_k127_1120716_0	292459.STH1455	2.785e-91	330.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158348_k127_1120716_1	479434.Sthe_3098	4.209e-65	235.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi,27XYY@189775|Thermomicrobia	189775|Thermomicrobia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
SRR25158348_k127_1121527_0	1192034.CAP_1968	1.606e-234	742.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YWI7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
SRR25158348_k127_1121638_0	502025.Hoch_4931	2.469e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1121638_1	457396.CSBG_02915	3.441e-10	64.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,36DM2@31979|Clostridiaceae	186801|Clostridia	O	PDZ DHR GLGF domain protein	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_1123908_0	404589.Anae109_0670	9.498e-55	210.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,42PS3@68525|delta/epsilon subdivisions,2X7MQ@28221|Deltaproteobacteria,2YVCB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_8
SRR25158348_k127_1128144_0	314278.NB231_03872	8.774e-194	625.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales	135613|Chromatiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158348_k127_1128144_4	247490.KSU1_C1008	1.458e-12	75.0	COG2980@1|root,COG2980@2|Bacteria,2J0MT@203682|Planctomycetes	203682|Planctomycetes	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SRR25158348_k127_1128144_3	344747.PM8797T_14224	4.126e-14	83.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,2J079@203682|Planctomycetes	203682|Planctomycetes	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,YfiO
SRR25158348_k127_1128144_1	1121468.AUBR01000009_gene2148	2.222e-97	342.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,42FA3@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
SRR25158348_k127_1128144_2	697282.Mettu_1027	5.503e-29	130.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XEUV@135618|Methylococcales	135618|Methylococcales	H	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158348_k127_1132661_1	1278073.MYSTI_06199	7.35e-44	167.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158348_k127_1132661_0	671143.DAMO_2305	1.937e-105	364.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.16.4	ko:K03587,ko:K08384,ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158348_k127_1132661_3	1176165.CAJD01000016_gene1236	2.18e-19	95.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4F9VN@85019|Brevibacteriaceae	201174|Actinobacteria	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158348_k127_1132661_4	194867.ALBQ01000023_gene3194	0.0004912	51.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_1132661_2	396588.Tgr7_0933	2.926e-26	119.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1WX0F@135613|Chromatiales	135613|Chromatiales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
SRR25158348_k127_1135038_1	1122137.AQXF01000001_gene3371	0.0003498	50.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1135038_0	404589.Anae109_3548	1.027e-56	218.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
SRR25158348_k127_1135332_1	1254432.SCE1572_26690	8.402e-08	61.0	2CD7S@1|root,32RX7@2|Bacteria,1R1U7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1135332_0	886293.Sinac_5675	1.815e-90	321.0	COG0128@1|root,COG0128@2|Bacteria,2IXRF@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158348_k127_11362_3	530564.Psta_4143	4.805e-08	58.0	2EK1E@1|root,33DRX@2|Bacteria,2J1JB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-RING_1
SRR25158348_k127_11362_0	1242864.D187_004787	3.054e-112	372.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,433XH@68525|delta/epsilon subdivisions,2X2FU@28221|Deltaproteobacteria,2YXR6@29|Myxococcales	28221|Deltaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158348_k127_11362_2	195250.CM001776_gene3375	5.855e-09	68.0	COG3055@1|root,COG3055@2|Bacteria,1GB99@1117|Cyanobacteria	1117|Cyanobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_5
SRR25158348_k127_1136470_0	309801.trd_1051	2.802e-05	55.0	COG5662@1|root,COG5662@2|Bacteria,2GBGZ@200795|Chloroflexi,27XXW@189775|Thermomicrobia	189775|Thermomicrobia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158348_k127_1145779_1	1196323.ALKF01000200_gene2764	2.81e-46	181.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HD4S@91061|Bacilli,26RK2@186822|Paenibacillaceae	91061|Bacilli	GT	Phosphoenolpyruvate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N
SRR25158348_k127_1145779_4	1379698.RBG1_1C00001G0667	2.154e-32	138.0	COG2110@1|root,COG2110@2|Bacteria,2NPPR@2323|unclassified Bacteria	2|Bacteria	S	Appr-1'-p processing enzyme	tfaE	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Caudo_TAP,Macro
SRR25158348_k127_1145779_2	661367.LLO_0299	9.004e-40	158.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1JEIC@118969|Legionellales	118969|Legionellales	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158348_k127_1145779_0	886293.Sinac_6891	1.926e-50	197.0	COG1999@1|root,COG2322@1|root,COG1999@2|Bacteria,COG2322@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
SRR25158348_k127_1145779_5	290397.Adeh_2272	2.295e-06	54.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WTH0@28221|Deltaproteobacteria,2YVPQ@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158348_k127_1145779_3	215803.DB30_7680	7.325e-38	149.0	COG1845@1|root,COG1845@2|Bacteria,1RI5A@1224|Proteobacteria,43B3F@68525|delta/epsilon subdivisions,2X6H7@28221|Deltaproteobacteria,2Z3B3@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158348_k127_1147242_2	1123368.AUIS01000011_gene1180	5.242e-36	156.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158348_k127_1147242_0	1121472.AQWN01000003_gene1534	2.308e-88	309.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
SRR25158348_k127_1147242_1	880073.Calab_1575	1.695e-41	157.0	COG2086@1|root,COG2086@2|Bacteria,2NP4J@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158348_k127_1149460_0	1379281.AVAG01000026_gene1626	7.375e-190	614.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2M8UV@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158348_k127_1149460_1	1121926.AXWO01000002_gene1626	3.676e-28	126.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4EY90@85014|Glycomycetales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_115772_0	247490.KSU1_C1202	1.322e-75	258.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158348_k127_115772_1	443254.Marpi_0885	3.92e-58	203.0	COG0048@1|root,COG0048@2|Bacteria,2GCYW@200918|Thermotogae	200918|Thermotogae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158348_k127_115772_2	1123242.JH636435_gene3135	5.316e-54	193.0	COG0049@1|root,COG0049@2|Bacteria,2IZ7I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158348_k127_115772_4	1128421.JAGA01000001_gene2144	4.401e-11	71.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158348_k127_115772_3	379066.GAU_1445	1.533e-19	91.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
SRR25158348_k127_116128_0	240016.ABIZ01000001_gene1248	1.215e-129	440.0	COG4206@1|root,COG4206@2|Bacteria,46Z2R@74201|Verrucomicrobia,2IU2X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158348_k127_116128_1	1231241.Mc24_03093	2.259e-62	226.0	COG0391@1|root,COG0391@2|Bacteria,2GCH9@200918|Thermotogae	200918|Thermotogae	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158348_k127_116128_2	498761.HM1_0070	2.416e-42	167.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,25CI8@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158348_k127_116128_3	871963.Desdi_3332	8.453e-15	78.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,262HD@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158348_k127_1163941_1	290397.Adeh_2607	8.36e-31	130.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158348_k127_1163941_3	1340493.JNIF01000003_gene2133	1.125e-05	51.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158348_k127_1163941_0	1009370.ALO_11584	4.343e-85	288.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4H27A@909932|Negativicutes	909932|Negativicutes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158348_k127_1163941_2	756499.Desde_2542	9.831e-14	74.0	COG4581@1|root,COG4581@2|Bacteria,1UYXS@1239|Firmicutes,25D2V@186801|Clostridia,26063@186807|Peptococcaceae	186801|Clostridia	L	Superfamily II RNA helicase	-	-	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C
SRR25158348_k127_1163972_1	436308.Nmar_0969	9.031e-38	151.0	arCOG05276@1|root,arCOG05276@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_excise
SRR25158348_k127_1163972_0	1210884.HG799462_gene8093	6.269e-86	294.0	COG0275@1|root,COG0275@2|Bacteria,2IXYS@203682|Planctomycetes	203682|Planctomycetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158348_k127_1163972_2	243233.MCA1041	4.969e-05	53.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XDNX@135618|Methylococcales	135618|Methylococcales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158348_k127_116429_0	485913.Krac_9804	1.23e-117	401.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158348_k127_116429_1	290397.Adeh_3375	1.289e-23	105.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,437IE@68525|delta/epsilon subdivisions,2WVS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158348_k127_1166602_4	90813.JQMT01000001_gene1971	1.346e-15	87.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,462WP@72273|Thiotrichales	72273|Thiotrichales	OU	Peptidase family S49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S49
SRR25158348_k127_1166602_0	107635.AZUO01000001_gene1019	3.789e-160	516.0	COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,2TTAU@28211|Alphaproteobacteria,36XB5@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158348_k127_1166602_3	472759.Nhal_1087	3.584e-26	117.0	COG0737@1|root,COG0737@2|Bacteria,1RFNB@1224|Proteobacteria	1224|Proteobacteria	C	oxidation-reduction process	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR25158348_k127_1166602_5	1454004.AW11_02917	6.742e-11	72.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_1166602_1	1125863.JAFN01000001_gene1528	2.009e-151	493.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_1166602_2	247490.KSU1_C0316	1.432e-36	149.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,2J515@203682|Planctomycetes	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRR25158348_k127_1167429_0	886293.Sinac_1832	2.017e-73	281.0	COG1196@1|root,COG2993@1|root,COG1196@2|Bacteria,COG2993@2|Bacteria	2|Bacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	CP_0623	-	2.7.11.1,3.1.21.3	ko:K00405,ko:K01153,ko:K09760,ko:K12132	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02048	3.D.4.3	-	-	Cytochrom_C,FixO
SRR25158348_k127_1170103_1	706587.Desti_4506	1.069e-127	422.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
SRR25158348_k127_1170103_5	344747.PM8797T_06722	8.071e-54	194.0	COG0233@1|root,COG0233@2|Bacteria,2IYYY@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158348_k127_1170103_3	765914.ThisiDRAFT_1082	6.391e-82	279.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158348_k127_1170103_6	1122223.KB890688_gene1763	2.474e-40	156.0	COG0264@1|root,COG0264@2|Bacteria,1WJ3W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158348_k127_1170103_4	344747.PM8797T_25970	1.39e-78	275.0	COG0052@1|root,COG0052@2|Bacteria,2IY9P@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158348_k127_1170103_2	247490.KSU1_D0086	1.315e-88	304.0	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158348_k127_1170103_0	330214.NIDE2074	8.822e-176	556.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
SRR25158348_k127_1172172_2	986075.CathTA2_1181	2.199e-48	187.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158348_k127_1172172_0	646529.Desaci_3733	2.007e-135	445.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158348_k127_1172172_3	1121918.ARWE01000001_gene1473	1.344e-35	141.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,43VJ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158348_k127_1172172_1	2325.TKV_c02430	1.155e-94	323.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,42EZ9@68295|Thermoanaerobacterales	186801|Clostridia	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158348_k127_1172897_2	555779.Dthio_PD2275	2.938e-21	102.0	COG0438@1|root,COG0438@2|Bacteria,1RA8H@1224|Proteobacteria,42RMM@68525|delta/epsilon subdivisions,2WNQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1172897_0	909663.KI867151_gene3002	2.427e-130	427.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2MQT9@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158348_k127_1172897_1	313624.NSP_45330	4.935e-45	167.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1G0WY@1117|Cyanobacteria,1HMIN@1161|Nostocales	1117|Cyanobacteria	CE	Glycine D-amino acid oxidase (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158348_k127_1173614_2	1219375.CM002139_gene879	2.023e-29	123.0	2EHW5@1|root,33BMQ@2|Bacteria,1P29Q@1224|Proteobacteria,1T710@1236|Gammaproteobacteria,1X8K7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1173614_0	314230.DSM3645_08617	4.011e-60	222.0	COG0009@1|root,COG0394@1|root,COG0009@2|Bacteria,COG0394@2|Bacteria,2IX5F@203682|Planctomycetes	203682|Planctomycetes	T	Belongs to the SUA5 family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,Sua5_yciO_yrdC
SRR25158348_k127_1173614_1	756272.Plabr_1998	5.778e-43	173.0	COG0698@1|root,COG0698@2|Bacteria,2IZKI@203682|Planctomycetes	203682|Planctomycetes	G	COG0698 Ribose 5-phosphate isomerase RpiB	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158348_k127_1174398_0	387092.NIS_0272	2.013e-223	711.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158348_k127_1176764_0	575540.Isop_3540	1.422e-37	163.0	COG1196@1|root,COG1196@2|Bacteria,2J548@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1177865_0	886293.Sinac_2774	1.816e-118	383.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FGE-sulfatase,TPR_11
SRR25158348_k127_1177865_1	530564.Psta_2597	5.504e-17	82.0	COG0307@1|root,COG0307@2|Bacteria,2IZ6H@203682|Planctomycetes	203682|Planctomycetes	H	riboflavin synthase alpha chain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158348_k127_1181304_0	1227497.C491_11498	8.72e-33	143.0	COG0365@1|root,arCOG04201@2157|Archaea,2XSTQ@28890|Euryarchaeota,23TRN@183963|Halobacteria	183963|Halobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding
SRR25158348_k127_1181681_0	644966.Tmar_1163	1.941e-135	436.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WD6G@538999|Clostridiales incertae sedis	186801|Clostridia	CE	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158348_k127_1183233_2	1232453.BAIF02000001_gene1416	7.977e-05	49.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,269FS@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158348_k127_1183233_1	1038866.KB902773_gene831	3.094e-24	109.0	COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,2U66D@28211|Alphaproteobacteria,3JV68@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
SRR25158348_k127_1183233_0	215803.DB30_2327	5.438e-70	244.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria,2YUCK@29|Myxococcales	28221|Deltaproteobacteria	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_1183233_3	111781.Lepto7376_4064	0.0002762	51.0	COG0577@1|root,COG0577@2|Bacteria,1G04T@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158348_k127_1185356_1	1242864.D187_003565	4.815e-28	123.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1185356_2	1282361.ABAC402_15915	5.768e-06	58.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,2UCUW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158348_k127_1185356_0	1535287.JP74_21580	1.191e-36	142.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2U9M1@28211|Alphaproteobacteria,3N72H@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
SRR25158348_k127_1185389_2	1454007.JAUG01000071_gene4051	3.108e-08	58.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
SRR25158348_k127_1185389_0	661478.OP10G_2775	1.327e-45	178.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158348_k127_1185389_1	1471459.JFLJ01000175_gene1818	3.283e-09	65.0	COG0457@1|root,COG0457@2|Bacteria	1471459.JFLJ01000175_gene1818|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1187725_0	247490.KSU1_D0801	7.593e-46	189.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
SRR25158348_k127_1189709_1	1121324.CLIT_10c02450	4.213e-55	201.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,25R5Q@186804|Peptostreptococcaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8
SRR25158348_k127_1189709_4	1463881.KL591016_gene5370	0.0003421	53.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria	201174|Actinobacteria	C	fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
SRR25158348_k127_1189709_0	595460.RRSWK_05217	2.133e-222	702.0	COG0504@1|root,COG0504@2|Bacteria,2IXNE@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158348_k127_1189709_3	1125863.JAFN01000001_gene385	1.312e-05	58.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR25158348_k127_1189709_2	1121937.AUHJ01000006_gene2541	1.393e-36	148.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,46AQ1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158348_k127_1191708_0	237368.SCABRO_03124	1.062e-37	150.0	COG1530@1|root,COG1530@2|Bacteria,2IWSS@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158348_k127_1191708_1	237368.SCABRO_03125	6.486e-33	138.0	COG5011@1|root,COG5011@2|Bacteria,2J018@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158348_k127_1191708_2	1165096.ARWF01000001_gene1816	2.354e-24	119.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KKNT@206350|Nitrosomonadales	206350|Nitrosomonadales	U	type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158348_k127_1191866_7	1380387.JADM01000014_gene4089	5.437e-21	95.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1XJZI@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158348_k127_1191866_1	429009.Adeg_0185	3.949e-105	351.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158348_k127_1191866_3	338963.Pcar_2406	4.483e-92	330.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,43TYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158348_k127_1191866_11	483219.LILAB_19350	3.431e-05	55.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,42WP0@68525|delta/epsilon subdivisions,2X6P7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	General secretion pathway protein C	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
SRR25158348_k127_1191866_6	243231.GSU1934	4.737e-26	116.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,43S2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
SRR25158348_k127_1191866_5	1030157.AFMP01000004_gene2050	7.428e-30	136.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2K0HT@204457|Sphingomonadales	204457|Sphingomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158348_k127_1191866_2	1121430.JMLG01000006_gene1764	1.777e-97	327.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,260AV@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158348_k127_1191866_0	370438.PTH_1811	4.358e-131	450.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158348_k127_1191866_10	880073.Calab_2435	1.174e-07	59.0	COG3688@1|root,COG3688@2|Bacteria,2NQ5V@2323|unclassified Bacteria	2|Bacteria	S	YacP-like NYN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_IV,GTP_EFTU,NYN_YacP
SRR25158348_k127_1191866_4	234267.Acid_1085	2.954e-69	246.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158348_k127_1191866_12	1123389.ATXJ01000032_gene1672	0.0001109	53.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158348_k127_1191866_9	1005705.HMPREF9967_1142	9.095e-11	71.0	COG1266@1|root,COG1266@2|Bacteria,1W74X@1239|Firmicutes,4I5C4@91061|Bacilli,43GCQ@68892|Streptococcus infantis	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158348_k127_1191866_8	1479235.KK366039_gene1337	3.974e-14	73.0	COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,1XK1W@135619|Oceanospirillales	135619|Oceanospirillales	S	glutamine	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158348_k127_1192961_1	296591.Bpro_2831	3.707e-54	194.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,4ACX8@80864|Comamonadaceae	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158348_k127_1192961_0	279714.FuraDRAFT_2563	3.119e-150	488.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,2VPRG@28216|Betaproteobacteria,2KSUP@206351|Neisseriales	206351|Neisseriales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158348_k127_1192961_3	886293.Sinac_3975	4.064e-27	125.0	COG0810@1|root,COG0810@2|Bacteria,2IZYP@203682|Planctomycetes	203682|Planctomycetes	M	carbohydrate binding	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
SRR25158348_k127_1192961_2	358681.BBR47_50240	1.301e-53	216.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,26V17@186822|Paenibacillaceae	91061|Bacilli	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	GATase1_like,VWA,VWA_2,VWA_3
SRR25158348_k127_1192961_4	1121428.DESHY_160218___1	2.561e-26	114.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,2611Z@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158348_k127_1196367_3	1150626.PHAMO_30144	1.864e-12	76.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2UHNB@28211|Alphaproteobacteria,2JUGI@204441|Rhodospirillales	204441|Rhodospirillales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158348_k127_1196367_4	1408422.JHYF01000010_gene3346	8.083e-06	57.0	COG0392@1|root,COG0392@2|Bacteria,1VC5W@1239|Firmicutes,24K4M@186801|Clostridia,36SCZ@31979|Clostridiaceae	186801|Clostridia	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158348_k127_1196367_0	1128421.JAGA01000003_gene2786	1.82e-44	167.0	COG1881@1|root,COG1881@2|Bacteria,2NPMM@2323|unclassified Bacteria	2|Bacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158348_k127_1196367_2	314230.DSM3645_05150	6.68e-13	79.0	COG1413@1|root,COG1413@2|Bacteria,2IZZR@203682|Planctomycetes	203682|Planctomycetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158348_k127_1196367_1	1144275.COCOR_06540	1.838e-34	145.0	COG5459@1|root,COG5459@2|Bacteria,1MWMM@1224|Proteobacteria,42WIB@68525|delta/epsilon subdivisions,2WRHR@28221|Deltaproteobacteria,2YZNU@29|Myxococcales	28221|Deltaproteobacteria	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
SRR25158348_k127_1196917_1	880073.Calab_2050	8.472e-118	387.0	COG0541@1|root,COG0541@2|Bacteria,2NNT9@2323|unclassified Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158348_k127_1196917_8	1077144.AGFF01000023_gene1191	8.366e-14	75.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158348_k127_1196917_6	1123508.JH636444_gene5248	8.586e-25	111.0	COG1595@1|root,COG1595@2|Bacteria,2IZPG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1196917_11	997346.HMPREF9374_1391	4.02e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,1TXBF@1239|Firmicutes,4I692@91061|Bacilli,27CE7@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158348_k127_1196917_7	1089547.KB913013_gene4233	6.931e-16	85.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,47S2S@768503|Cytophagia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_1196917_2	886293.Sinac_6081	2.402e-100	348.0	28M0D@1|root,2ZAFE@2|Bacteria,2IX4T@203682|Planctomycetes	203682|Planctomycetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
SRR25158348_k127_1196917_3	575540.Isop_0192	2.57e-79	284.0	COG1131@1|root,COG1131@2|Bacteria,2IYTF@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_1196917_0	237368.SCABRO_00428	6.168e-130	428.0	COG0617@1|root,COG0617@2|Bacteria,2IXYM@203682|Planctomycetes	203682|Planctomycetes	H	tRNA nucleotidyltransferase poly(A) polymerase	papS	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158348_k127_1196917_4	247490.KSU1_B0249	1.502e-77	268.0	COG1192@1|root,COG1192@2|Bacteria,2IX5Z@203682|Planctomycetes	203682|Planctomycetes	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158348_k127_1196917_9	502025.Hoch_3232	5.073e-07	61.0	COG3540@1|root,COG5083@1|root,COG3540@2|Bacteria,COG5083@2|Bacteria,1PI5U@1224|Proteobacteria,43DVA@68525|delta/epsilon subdivisions,2X8XW@28221|Deltaproteobacteria,2Z0Z1@29|Myxococcales	28221|Deltaproteobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158348_k127_1196917_10	1120983.KB894571_gene2690	2.808e-05	55.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,1JP5V@119043|Rhodobiaceae	28211|Alphaproteobacteria	CO	Thioredoxin-like	tlpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158348_k127_1196917_5	1121091.AUMP01000033_gene1564	6.463e-26	113.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1197612_4	713587.THITH_02425	2.541e-12	80.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1WYIT@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158348_k127_1197612_0	1123261.AXDW01000024_gene2052	3.12e-100	344.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1X5E9@135614|Xanthomonadales	135614|Xanthomonadales	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
SRR25158348_k127_1197612_3	525904.Tter_1099	1.98e-17	97.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1197612_2	247490.KSU1_B0672	7.299e-53	202.0	COG2385@1|root,COG2385@2|Bacteria,2J08W@203682|Planctomycetes	203682|Planctomycetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158348_k127_1197612_5	573061.Clocel_0309	3.895e-11	76.0	COG3055@1|root,COG3055@2|Bacteria,1V5WF@1239|Firmicutes,24H47@186801|Clostridia,36IV6@31979|Clostridiaceae	186801|Clostridia	N	PFAM Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1
SRR25158348_k127_1197612_1	1304880.JAGB01000002_gene1921	2.96e-74	261.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS19425	PMI_typeI
SRR25158348_k127_1197612_6	1042163.BRLA_c019210	0.0003328	44.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,26Y3B@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158348_k127_1206242_0	999611.KI421504_gene1954	1.482e-50	183.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,280FA@191028|Leisingera	28211|Alphaproteobacteria	O	TCP-1/cpn60 chaperonin family	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158348_k127_1206242_2	1267534.KB906757_gene764	6.535e-15	85.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria,2JJ61@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158348_k127_1206242_1	682795.AciX8_3688	2.74e-18	98.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria,2JJ61@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158348_k127_1214815_0	1048834.TC41_0106	3.887e-28	118.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,278YM@186823|Alicyclobacillaceae	91061|Bacilli	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158348_k127_1214943_1	243233.MCA1429	7.1e-63	237.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1QY3G@1224|Proteobacteria,1SN4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1214943_0	1521187.JPIM01000005_gene2285	1.456e-66	247.0	COG1366@1|root,COG1922@1|root,COG1366@2|Bacteria,COG1922@2|Bacteria,2G6J0@200795|Chloroflexi,375GH@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferase, WecB TagA CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB,STAS
SRR25158348_k127_1214943_2	118161.KB235922_gene1936	1.204e-20	105.0	COG2244@1|root,COG2244@2|Bacteria,1FZXI@1117|Cyanobacteria,3VM3X@52604|Pleurocapsales	1117|Cyanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
SRR25158348_k127_1217609_0	521045.Kole_2020	2.468e-44	163.0	COG0057@1|root,COG0057@2|Bacteria,2GCBQ@200918|Thermotogae	200918|Thermotogae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158348_k127_1217829_0	1259795.ARJK01000003_gene952	8.115e-33	134.0	COG0477@1|root,COG2814@2|Bacteria,1TS1D@1239|Firmicutes,24CUT@186801|Clostridia,42J9F@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158348_k127_1221690_0	247490.KSU1_B0240	5.797e-37	157.0	2CFWI@1|root,32S2N@2|Bacteria,2J08K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1221690_1	880073.Calab_3019	1.507e-29	131.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158348_k127_1221690_2	300852.55772039	0.0004793	45.0	COG1385@1|root,COG1385@2|Bacteria,1WJE1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158348_k127_1222440_1	82654.Pse7367_0584	5.726e-40	167.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SRR25158348_k127_1222440_3	1048834.TC41_2936	4.769e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1222440_0	324602.Caur_3368	7.387e-49	185.0	COG2360@1|root,COG2360@2|Bacteria,2G8HE@200795|Chloroflexi,375I4@32061|Chloroflexia	32061|Chloroflexia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158348_k127_1224638_2	1142394.PSMK_23760	6.437e-06	49.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158348_k127_1224638_0	338963.Pcar_0729	2.769e-27	119.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,43V08@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158348_k127_1224638_1	1122918.KB907250_gene3754	7.368e-10	71.0	COG1595@1|root,COG1595@2|Bacteria,1U40C@1239|Firmicutes,4HCU0@91061|Bacilli,26S2C@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW11	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1224995_0	237368.SCABRO_01466	8.699e-76	273.0	COG0770@1|root,COG0770@2|Bacteria,2IXKX@203682|Planctomycetes	203682|Planctomycetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158348_k127_1224995_1	1487923.DP73_07125	4.337e-05	46.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158348_k127_1229960_0	204669.Acid345_0454	3.455e-85	285.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3Y47M@57723|Acidobacteria	57723|Acidobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158348_k127_1229960_1	204669.Acid345_0453	3.953e-85	287.0	COG0243@1|root,COG0243@2|Bacteria,3Y7US@57723|Acidobacteria	57723|Acidobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
SRR25158348_k127_1229960_2	859657.RPSI07_mp0756	2.811e-49	194.0	COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,1RB38@1224|Proteobacteria,2VSAM@28216|Betaproteobacteria,1KHW5@119060|Burkholderiaceae	28216|Betaproteobacteria	G	3-carboxymuconate cyclase quinoprotein amine dehydrogenase, beta chain-like	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158348_k127_1229960_3	929713.NIASO_04475	5.288e-07	62.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,4NGKT@976|Bacteroidetes,1IW42@117747|Sphingobacteriia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
SRR25158348_k127_1240095_2	401053.AciPR4_2010	1.111e-52	196.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia	204432|Acidobacteriia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158348_k127_1240095_1	861299.J421_5582	7.367e-84	287.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158348_k127_1240095_0	1380394.JADL01000017_gene521	2.499e-161	523.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,2UQVT@28211|Alphaproteobacteria,2JW8F@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158348_k127_1240095_3	1166948.JPZL01000002_gene1293	1.953e-14	73.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,1RYKP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158348_k127_1244086_2	1379698.RBG1_1C00001G1744	1.05e-44	168.0	COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SRR25158348_k127_1244086_3	530564.Psta_4143	5.705e-18	94.0	2EK1E@1|root,33DRX@2|Bacteria,2J1JB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-RING_1
SRR25158348_k127_1244086_1	575540.Isop_1088	3.329e-110	365.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158348_k127_1244086_0	530564.Psta_1424	1.503e-127	435.0	COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158348_k127_1249659_3	1232410.KI421414_gene2895	5.872e-23	107.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158348_k127_1249659_0	203119.Cthe_0686	2.453e-121	397.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158348_k127_1249659_1	1123376.AUIU01000011_gene879	1.795e-39	160.0	COG1994@1|root,COG1994@2|Bacteria,3J14Q@40117|Nitrospirae	40117|Nitrospirae	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158348_k127_1249659_2	266117.Rxyl_1623	5.028e-36	146.0	COG1040@1|root,COG1040@2|Bacteria,2HP3J@201174|Actinobacteria,4CQES@84995|Rubrobacteria	84995|Rubrobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158348_k127_1251201_2	1123508.JH636440_gene2050	0.0006452	48.0	2EFGY@1|root,3399I@2|Bacteria,2J10Z@203682|Planctomycetes	1123508.JH636440_gene2050|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1251201_1	886293.Sinac_2922	8.239e-70	256.0	COG5492@1|root,COG5492@2|Bacteria,2IXS3@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
SRR25158348_k127_1251201_0	530564.Psta_2125	2.83e-93	321.0	COG4102@1|root,COG4102@2|Bacteria,2IYAK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158348_k127_1258586_3	351160.RCIX924	3.262e-33	138.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158348_k127_1258586_2	1183438.GKIL_2953	4.229e-58	215.0	COG1670@1|root,COG1670@2|Bacteria,1G621@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158348_k127_1258586_1	1183438.GKIL_2953	1.81e-72	253.0	COG1670@1|root,COG1670@2|Bacteria,1G621@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158348_k127_1258586_0	706587.Desti_4506	4.996e-73	251.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
SRR25158348_k127_1258944_2	330214.NIDE3016	1.032e-21	96.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158348_k127_1258944_0	1144275.COCOR_03012	8.873e-99	328.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2YUEF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158348_k127_1258944_3	1000565.METUNv1_01916	5.969e-14	82.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,2KX6R@206389|Rhodocyclales	206389|Rhodocyclales	H	COG2104 Sulfur transfer protein involved in thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158348_k127_1258944_1	290397.Adeh_0658	1.799e-25	113.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQJT@28221|Deltaproteobacteria,2YV3J@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx GppA	gppA-1	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158348_k127_1263347_2	1123242.JH636434_gene3995	8.72e-05	50.0	COG4372@1|root,COG4372@2|Bacteria,2IZX3@203682|Planctomycetes	203682|Planctomycetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1263347_0	247490.KSU1_C0171	1.456e-134	440.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158348_k127_1263347_1	253839.SSNG_04468	9.013e-20	91.0	COG0736@1|root,COG0736@2|Bacteria,2IPP4@201174|Actinobacteria	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	-	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158348_k127_12657_0	1379698.RBG1_1C00001G0804	2.138e-40	154.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158348_k127_12657_1	330214.NIDE3438	0.0003582	51.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
SRR25158348_k127_12657_2	195103.CPF_2567	0.00054	51.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
SRR25158348_k127_12657_3	1111069.TCCBUS3UF1_8680	0.0007134	51.0	COG2165@1|root,COG2165@2|Bacteria,1WKEM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	general secretion pathway protein	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
SRR25158348_k127_1270942_0	754476.Q7A_2537	2.022e-26	112.0	COG2199@1|root,COG2199@2|Bacteria,1QTZT@1224|Proteobacteria,1T1J9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,GGDEF,HAMP,HisKA_7TM,PAS_4,PAS_8
SRR25158348_k127_1270942_1	234267.Acid_4992	1.721e-25	123.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NZ@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158348_k127_1270942_2	1173022.Cri9333_2475	0.0001122	52.0	COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales	1117|Cyanobacteria	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
SRR25158348_k127_1276343_4	671143.DAMO_3012	1.003e-113	377.0	COG2805@1|root,COG2805@2|Bacteria,2NNR7@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158348_k127_1276343_2	398767.Glov_1319	1.908e-170	557.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	elongation factor G domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158348_k127_1276343_10	237368.SCABRO_03873	2.097e-27	120.0	COG1360@1|root,COG1360@2|Bacteria,2IZSF@203682|Planctomycetes	203682|Planctomycetes	N	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158348_k127_1276343_7	886293.Sinac_2635	5.057e-55	204.0	COG1989@1|root,COG1989@2|Bacteria,2IZQ8@203682|Planctomycetes	203682|Planctomycetes	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158348_k127_1276343_6	237368.SCABRO_03354	1.577e-73	268.0	COG0202@1|root,COG0457@1|root,COG0202@2|Bacteria,COG0457@2|Bacteria,2IXMK@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase alpha	-	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,TPR_1,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158348_k127_1276343_11	635013.TherJR_2451	1.367e-26	115.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158348_k127_1276343_5	706587.Desti_3152	3.855e-107	380.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2MQA6@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158348_k127_1276343_0	1122223.KB890699_gene581	4.026e-183	587.0	COG0459@1|root,COG0459@2|Bacteria,1WIFZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158348_k127_1276343_9	515635.Dtur_0958	1.141e-33	132.0	COG0234@1|root,COG0234@2|Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158348_k127_1276343_1	756272.Plabr_3980	3.056e-176	568.0	COG0459@1|root,COG0459@2|Bacteria,2IWZS@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158348_k127_1276343_14	929703.KE386491_gene3755	9.766e-05	53.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NS5V@976|Bacteroidetes,47RNH@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_16,TPR_2,TPR_8
SRR25158348_k127_1276343_13	879212.DespoDRAFT_00973	5.693e-19	98.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_1276343_8	1042375.AFPL01000031_gene817	1.392e-39	169.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,466J6@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
SRR25158348_k127_1276343_3	562970.Btus_1805	1.41e-138	461.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,2784J@186823|Alicyclobacillaceae	91061|Bacilli	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158348_k127_1276343_12	234267.Acid_3676	1.401e-25	107.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158348_k127_1279671_0	1403819.BATR01000162_gene5395	2.112e-116	385.0	COG0457@1|root,COG0457@2|Bacteria,46W9Q@74201|Verrucomicrobia,2IVDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1279671_1	1144307.PMI04_03372	3.132e-17	88.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
SRR25158348_k127_1285988_4	760568.Desku_1744	1.539e-15	81.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158348_k127_1285988_1	237368.SCABRO_03272	1.874e-95	319.0	COG0777@1|root,COG0777@2|Bacteria,2IXWA@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158348_k127_1285988_2	626939.HMPREF9443_00842	1.014e-62	223.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H407@909932|Negativicutes	909932|Negativicutes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158348_k127_1285988_0	1232410.KI421413_gene532	3.971e-137	446.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,43S14@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158348_k127_1285988_3	575540.Isop_3519	2.45e-46	169.0	COG0057@1|root,COG0057@2|Bacteria,2IX66@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158348_k127_1290968_0	1123508.JH636439_gene1132	1.931e-83	306.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
SRR25158348_k127_1290968_1	292564.Cyagr_3100	2.494e-06	52.0	2BP4Z@1|root,32HVT@2|Bacteria,1GMQJ@1117|Cyanobacteria,22TQW@167375|Cyanobium	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_129723_0	1121468.AUBR01000034_gene1378	2.675e-111	368.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
SRR25158348_k127_129723_1	518766.Rmar_2526	5.599e-37	157.0	COG1514@1|root,COG1514@2|Bacteria,4NVYJ@976|Bacteroidetes	976|Bacteroidetes	L	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,Exo_endo_phos,PAP_central
SRR25158348_k127_129723_2	1380390.JIAT01000010_gene3840	7.849e-13	75.0	COG3920@1|root,COG5002@1|root,COG3920@2|Bacteria,COG5002@2|Bacteria,2HFEI@201174|Actinobacteria,4CTJF@84995|Rubrobacteria	84995|Rubrobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS
SRR25158348_k127_1299170_2	378806.STAUR_6445	3.928e-27	124.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158348_k127_1299170_4	231434.JQJH01000003_gene415	3.328e-26	114.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TU0G@28211|Alphaproteobacteria,3NB79@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158348_k127_1299170_1	1201288.M900_1653	2.054e-43	181.0	COG0457@1|root,COG0457@2|Bacteria,1QY1G@1224|Proteobacteria,43C8T@68525|delta/epsilon subdivisions,2MUD4@213481|Bdellovibrionales,2X7J5@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
SRR25158348_k127_1299170_6	1128421.JAGA01000002_gene1696	1.073e-16	95.0	COG2146@1|root,COG2146@2|Bacteria,2NQ38@2323|unclassified Bacteria	2|Bacteria	P	(Rieske (2Fe-2S) domain)	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Ferric_reduct,Rieske,Rieske_2
SRR25158348_k127_1299170_5	1071073.KI530537_gene1892	3.701e-20	102.0	COG0454@1|root,COG0456@2|Bacteria,1UZC5@1239|Firmicutes,4HFDR@91061|Bacilli,1ZE2E@1386|Bacillus	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158348_k127_1299170_0	1123508.JH636446_gene6369	2.17e-148	507.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158348_k127_1299170_7	365528.KB891137_gene379	8.072e-05	55.0	COG1361@1|root,COG4625@1|root,COG4719@1|root,COG1361@2|Bacteria,COG4625@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria	201174|Actinobacteria	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
SRR25158348_k127_1299170_3	1499967.BAYZ01000100_gene3449	1.044e-26	113.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158348_k127_1299549_1	1408324.JNJK01000013_gene63	2.564e-42	161.0	COG1310@1|root,COG1310@2|Bacteria,1VQJE@1239|Firmicutes,24CU8@186801|Clostridia	186801|Clostridia	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	JAB,LysM
SRR25158348_k127_1299549_0	886293.Sinac_1732	1.225e-44	177.0	COG5078@1|root,COG5078@2|Bacteria,2IZW0@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Ubiquitin-conjugating	-	-	-	-	-	-	-	-	-	-	-	-	UQ_con
SRR25158348_k127_1299549_2	530564.Psta_4149	5.437e-37	141.0	2EFHE@1|root,3399Z@2|Bacteria,2J10E@203682|Planctomycetes	203682|Planctomycetes	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
SRR25158348_k127_1299549_3	326424.FRAAL0856	0.0001603	46.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158348_k127_1307558_1	1423755.BAML01000008_gene734	6.666e-27	112.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae	91061|Bacilli	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158348_k127_1307558_0	518766.Rmar_2305	2.091e-67	245.0	COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1FJWC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
SRR25158348_k127_1315995_0	575540.Isop_1295	1.491e-74	263.0	COG4102@1|root,COG4102@2|Bacteria,2IXKF@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158348_k127_1315995_1	36331.EPrPI00000018052	3.517e-20	97.0	COG2340@1|root,2R9D2@2759|Eukaryota,1MJF4@121069|Pythiales	121069|Pythiales	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158348_k127_1315995_2	1127134.NOCYR_2232	1.246e-11	76.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria,4FU8S@85025|Nocardiaceae	201174|Actinobacteria	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
SRR25158348_k127_1317346_0	671143.DAMO_0810	7.653e-74	252.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158348_k127_1323093_0	1235797.C816_02457	1.633e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,2N772@216572|Oscillospiraceae	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1323093_1	1068980.ARVW01000001_gene6032	0.0001089	54.0	COG5662@1|root,COG5662@2|Bacteria,2HG2K@201174|Actinobacteria,4E2QA@85010|Pseudonocardiales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
SRR25158348_k127_1328590_1	204669.Acid345_0455	1.686e-36	148.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD
SRR25158348_k127_1328590_0	204669.Acid345_0454	7.508e-213	666.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3Y47M@57723|Acidobacteria	57723|Acidobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158348_k127_1331231_1	13689.BV96_04167	4.125e-06	59.0	COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,2U7GV@28211|Alphaproteobacteria,2K4V0@204457|Sphingomonadales	204457|Sphingomonadales	PT	FecR protein	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,FecR
SRR25158348_k127_1331231_0	1121422.AUMW01000024_gene240	3.862e-22	103.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1333099_1	945713.IALB_2105	2.146e-36	139.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria	2|Bacteria	H	GTP cyclohydrolase II activity	ribBA	-	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158348_k127_1333099_0	398767.Glov_2172	1.074e-89	307.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158348_k127_1333099_3	408672.NBCG_01597	1.422e-14	84.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DSRC@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,HTH_31
SRR25158348_k127_1333099_2	1242864.D187_003815	6.726e-17	91.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SRR25158348_k127_1354203_0	1379698.RBG1_1C00001G1223	3.566e-72	254.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158348_k127_1354203_3	515635.Dtur_1336	4.613e-41	156.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158348_k127_1354203_2	247490.KSU1_C1554	1.442e-57	211.0	COG0571@1|root,COG0571@2|Bacteria,2IYW1@203682|Planctomycetes	203682|Planctomycetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158348_k127_1354203_1	314230.DSM3645_08061	3.121e-66	243.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158348_k127_1357902_1	1458357.BG58_03515	3.225e-19	102.0	COG0304@1|root,COG0304@2|Bacteria,1R618@1224|Proteobacteria,2VW53@28216|Betaproteobacteria,1KB2X@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	synthase	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ketoacyl-synt
SRR25158348_k127_1357902_0	1504672.669787504	1.039e-92	315.0	COG5351@1|root,COG5351@2|Bacteria,1R3ZF@1224|Proteobacteria,2VS1K@28216|Betaproteobacteria,4AERZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169
SRR25158348_k127_1359885_3	926566.Terro_1530	0.0001356	54.0	COG0101@1|root,COG0101@2|Bacteria,3Y2MS@57723|Acidobacteria,2JIWS@204432|Acidobacteriia	204432|Acidobacteriia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158348_k127_1359885_0	247490.KSU1_C0305	1.072e-112	373.0	COG0136@1|root,COG0136@2|Bacteria,2IY8G@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158348_k127_1359885_1	292459.STH2903	8.315e-50	186.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158348_k127_1359885_2	378806.STAUR_3876	1.287e-15	77.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria,2YX8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158348_k127_1360126_0	1123508.JH636444_gene5501	3.388e-56	215.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
SRR25158348_k127_1360703_2	443144.GM21_1472	1.316e-37	144.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
SRR25158348_k127_1360703_4	247490.KSU1_B0545	7.483e-31	130.0	COG1825@1|root,COG1825@2|Bacteria,2J050@203682|Planctomycetes	203682|Planctomycetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158348_k127_1360703_1	1122216.AUHW01000015_gene2026	9.484e-39	151.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4H4AW@909932|Negativicutes	909932|Negativicutes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158348_k127_1360703_7	306264.CUP0904	2.403e-12	72.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2YPZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158348_k127_1360703_3	243090.RB9917	2.973e-36	147.0	COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes	203682|Planctomycetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158348_k127_1360703_6	886293.Sinac_5244	3.367e-18	87.0	COG0238@1|root,COG0238@2|Bacteria,2J0IC@203682|Planctomycetes	203682|Planctomycetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158348_k127_1360703_5	1209989.TepiRe1_2821	1.57e-26	117.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,42GRT@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158348_k127_1360703_0	247490.KSU1_B0551	5.18e-103	347.0	COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes	203682|Planctomycetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158348_k127_1362761_3	857293.CAAU_2156	7.072e-11	65.0	2BYY4@1|root,2Z80Y@2|Bacteria,1TSXF@1239|Firmicutes,24B6G@186801|Clostridia,36EPB@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4438)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4438
SRR25158348_k127_1362761_2	880073.Calab_3405	1.38e-48	192.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
SRR25158348_k127_1362761_1	886293.Sinac_6457	2.305e-118	395.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158348_k127_1362761_0	247490.KSU1_C1455	2.509e-136	441.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158348_k127_1364478_0	1123073.KB899242_gene1657	4.11e-97	331.0	COG3391@1|root,COG3391@2|Bacteria,1MY07@1224|Proteobacteria	1224|Proteobacteria	O	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1364478_1	861299.J421_5889	5.734e-33	134.0	2DSP1@1|root,33GVU@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
SRR25158348_k127_1364478_2	237727.NAP1_11743	1.081e-12	73.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,2KD9Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
SRR25158348_k127_1369298_2	1125863.JAFN01000001_gene902	4.009e-13	74.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158348_k127_1369298_0	575540.Isop_0532	7.954e-75	265.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_1369298_1	1209989.TepiRe1_0236	1.893e-56	203.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42FMH@68295|Thermoanaerobacterales	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158348_k127_1374201_0	575540.Isop_2783	4.897e-194	617.0	COG0556@1|root,COG0556@2|Bacteria,2IWS1@203682|Planctomycetes	203682|Planctomycetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158348_k127_1375373_0	324057.Pjdr2_5722	7.829e-145	474.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,4HBRF@91061|Bacilli,26S4Y@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase U32	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
SRR25158348_k127_1375373_3	243231.GSU1638	4.866e-27	117.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158348_k127_1375373_1	794903.OPIT5_26470	1.625e-120	403.0	COG2897@1|root,COG2897@2|Bacteria,46SFU@74201|Verrucomicrobia,3K9H0@414999|Opitutae	414999|Opitutae	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158348_k127_1375373_2	1197906.CAJQ02000009_gene3553	7.209e-82	289.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2TU5N@28211|Alphaproteobacteria,3JUHK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158348_k127_1382756_2	204669.Acid345_0455	1.188e-48	179.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD
SRR25158348_k127_1382756_1	204669.Acid345_0456	9.395e-65	238.0	COG3058@1|root,COG3058@2|Bacteria	2|Bacteria	O	ferric iron binding	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
SRR25158348_k127_1382756_0	344747.PM8797T_03680	1.007e-79	273.0	COG3361@1|root,COG3361@2|Bacteria,2IYZC@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
SRR25158348_k127_1382756_3	595460.RRSWK_03890	4.075e-32	131.0	COG1446@1|root,COG4319@1|root,COG1446@2|Bacteria,COG4319@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
SRR25158348_k127_1382756_5	387631.Asulf_00300	1.723e-05	51.0	COG3350@1|root,arCOG04507@2157|Archaea	2157|Archaea	P	PFAM YHS domain	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158348_k127_1382756_4	1499683.CCFF01000016_gene659	8.218e-06	53.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,36E39@31979|Clostridiaceae	186801|Clostridia	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N,PRC
SRR25158348_k127_1388440_0	1379698.RBG1_1C00001G0513	2.338e-135	440.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158348_k127_1388440_1	68170.KL590496_gene9346	3.231e-24	118.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4E32I@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158348_k127_1390281_2	234267.Acid_7701	1.08e-85	302.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158348_k127_1390281_1	948106.AWZT01000053_gene1578	1.083e-108	375.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria,1K5H7@119060|Burkholderiaceae	28216|Betaproteobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158348_k127_1390281_0	671143.DAMO_2383	1.826e-254	790.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
SRR25158348_k127_1390281_3	1123073.KB899241_gene1907	5.642e-38	147.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158348_k127_1390281_4	290397.Adeh_2848	7.108e-36	151.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158348_k127_1402972_1	1254432.SCE1572_30305	1.561e-52	188.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,42M4A@68525|delta/epsilon subdivisions,2WJKU@28221|Deltaproteobacteria,2YUDW@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	tssC	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
SRR25158348_k127_1402972_0	1007105.PT7_2341	5.157e-58	205.0	COG3516@1|root,COG3516@2|Bacteria,1RBNB@1224|Proteobacteria,2WGCY@28216|Betaproteobacteria,3T5GF@506|Alcaligenaceae	28216|Betaproteobacteria	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
SRR25158348_k127_1402972_2	331869.BAL199_01464	9.322e-51	200.0	COG3515@1|root,COG3515@2|Bacteria,1NKX3@1224|Proteobacteria,2U06Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ	-	-	-	-	-	-	-	-	-	-	-	-	ImpA_N,T6SS_VasJ
SRR25158348_k127_1402972_3	1242864.D187_009097	8.93e-11	72.0	COG3913@1|root,COG3913@2|Bacteria	2|Bacteria	T	Uncharacterized protein conserved in bacteria (DUF2094)	-	-	-	ko:K11890,ko:K11910	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF2094
SRR25158348_k127_1408051_1	742727.HMPREF9447_04652	6.608e-05	51.0	2E52N@1|root,32ZVW@2|Bacteria,4NZ25@976|Bacteroidetes,2FVD6@200643|Bacteroidia,4AV0C@815|Bacteroidaceae	976|Bacteroidetes	S	SMI1 / KNR4 family	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4
SRR25158348_k127_1408051_0	395961.Cyan7425_1833	5.478e-60	216.0	COG0058@1|root,COG0058@2|Bacteria,1G1HB@1117|Cyanobacteria	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158348_k127_1411377_2	1203554.HMPREF1476_01597	3.212e-46	171.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,4PQNZ@995019|Sutterellaceae	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158348_k127_1411377_1	1304880.JAGB01000003_gene1306	1.157e-123	414.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158348_k127_1411377_0	572477.Alvin_1302	6.37e-126	407.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WXCM@135613|Chromatiales	135613|Chromatiales	S	PFAM Polyphosphate kinase 2	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158348_k127_1411377_3	391038.Bphy_2397	4.986e-09	67.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1K18V@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
SRR25158348_k127_1413_0	279714.FuraDRAFT_2562	9.867e-155	497.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,2KQFQ@206351|Neisseriales	206351|Neisseriales	E	Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158348_k127_1413_1	667014.Thein_0619	8.002e-100	347.0	COG0460@1|root,COG0460@2|Bacteria,2GH5Y@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158348_k127_1413_3	1220534.B655_0330	9.825e-09	67.0	COG5635@1|root,arCOG06468@1|root,arCOG02967@2157|Archaea,arCOG06468@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
SRR25158348_k127_1413_2	756272.Plabr_2828	6.31e-10	64.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	oapA	-	2.7.11.1	ko:K02451,ko:K03086,ko:K07268,ko:K08884	-	M00331	-	-	ko00000,ko00002,ko01000,ko01001,ko02044,ko03021	9.B.42	-	-	Collagen,OapA,OapA_N,SPOR,T2SSB
SRR25158348_k127_1413716_3	1242864.D187_006544	2.14e-36	145.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158348_k127_1413716_1	1123371.ATXH01000019_gene615	1.367e-102	342.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158348_k127_1413716_0	1210884.HG799471_gene14727	7.194e-125	411.0	COG0513@1|root,COG0513@2|Bacteria,2IX18@203682|Planctomycetes	203682|Planctomycetes	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158348_k127_1413716_4	1123261.AXDW01000001_gene1272	3.319e-33	132.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1X77N@135614|Xanthomonadales	135614|Xanthomonadales	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158348_k127_1413716_2	234267.Acid_0588	3.043e-51	186.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158348_k127_1416319_3	525257.HMPREF0204_13956	7.521e-18	95.0	COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1HY7J@117743|Flavobacteriia,3ZRC1@59732|Chryseobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
SRR25158348_k127_1416319_1	1296415.JACC01000046_gene721	5.451e-72	255.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HWM7@117743|Flavobacteriia,2YH81@290174|Aquimarina	976|Bacteroidetes	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158348_k127_1416319_2	886293.Sinac_1023	9.315e-54	207.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
SRR25158348_k127_1416319_0	1463857.JOFZ01000006_gene3491	1.481e-142	464.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158348_k127_1422112_2	1487921.DP68_12865	7.201e-54	210.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158348_k127_1422112_1	1449080.JQMV01000003_gene506	6.836e-96	325.0	COG0601@1|root,COG0601@2|Bacteria,1WIGY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158348_k127_1422112_0	1120973.AQXL01000122_gene191	1.1e-112	383.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,278QJ@186823|Alicyclobacillaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	dppA_1	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158348_k127_1428726_2	1254432.SCE1572_29395	2.59e-66	248.0	COG2312@1|root,COG2312@2|Bacteria,1NEZB@1224|Proteobacteria,433VP@68525|delta/epsilon subdivisions,2X3PC@28221|Deltaproteobacteria,2YWR8@29|Myxococcales	28221|Deltaproteobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg,Erythro_esteras
SRR25158348_k127_1428726_0	1379698.RBG1_1C00001G0684	2.947e-165	532.0	COG0277@1|root,COG0277@2|Bacteria,2NP1E@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104,ko:K18930	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158348_k127_1428726_4	204669.Acid345_3007	2.728e-36	150.0	COG1409@1|root,COG1409@2|Bacteria,3Y5PM@57723|Acidobacteria,2JN3H@204432|Acidobacteriia	204432|Acidobacteriia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158348_k127_1428726_3	396588.Tgr7_3179	1.087e-59	221.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,1X059@135613|Chromatiales	135613|Chromatiales	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158348_k127_1428726_5	248742.XP_005648531.1	0.000408	52.0	COG3914@1|root,KOG4626@2759|Eukaryota,389V1@33090|Viridiplantae,34PF1@3041|Chlorophyta	3041|Chlorophyta	GOT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2
SRR25158348_k127_1428726_1	556263.FSEG_01363	1.003e-82	287.0	COG1171@1|root,COG1171@2|Bacteria,378K1@32066|Fusobacteria	32066|Fusobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158348_k127_142974_1	247490.KSU1_C1197	3.227e-54	193.0	COG0080@1|root,COG0080@2|Bacteria,2IZ97@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158348_k127_142974_0	247490.KSU1_C1198	2.344e-84	287.0	COG0081@1|root,COG0081@2|Bacteria,2IYQK@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158348_k127_142974_2	330214.NIDE1302	1.761e-07	63.0	COG0222@1|root,COG0244@1|root,COG0222@2|Bacteria,COG0244@2|Bacteria,3J0NQ@40117|Nitrospirae	40117|Nitrospirae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158348_k127_1436096_2	247490.KSU1_B0639	6.596e-61	219.0	COG1774@1|root,COG1774@2|Bacteria,2IWZD@203682|Planctomycetes	203682|Planctomycetes	S	signal peptidase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR25158348_k127_1436096_1	1123508.JH636445_gene6594	4.46e-111	371.0	COG0821@1|root,COG0821@2|Bacteria,2IXN9@203682|Planctomycetes	203682|Planctomycetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158348_k127_1436096_0	243231.GSU2974	7.18e-174	564.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,43SUD@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
SRR25158348_k127_1436096_3	504487.JCM19302_2075	1.887e-06	55.0	COG5276@1|root,COG5276@2|Bacteria,4NPJY@976|Bacteroidetes,1I2K9@117743|Flavobacteriia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SusE,fn3
SRR25158348_k127_1437539_0	443144.GM21_0751	6.959e-113	381.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WJQV@28221|Deltaproteobacteria,43S19@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158348_k127_1437539_1	428125.CLOLEP_01062	2.473e-49	186.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3WK6T@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158348_k127_143896_0	765913.ThidrDRAFT_2868	3.391e-212	685.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales	135613|Chromatiales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158348_k127_143896_3	1192034.CAP_6221	2.956e-35	139.0	COG0640@1|root,COG0640@2|Bacteria,1N4FB@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158348_k127_143896_2	273526.SMDB11_1802	2.767e-54	199.0	COG3832@1|root,COG3832@2|Bacteria,1RHJJ@1224|Proteobacteria,1S850@1236|Gammaproteobacteria,3ZZVK@613|Serratia	1236|Gammaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158348_k127_143896_1	404589.Anae109_3662	3.579e-60	220.0	COG3832@1|root,COG3832@2|Bacteria,1RJ9N@1224|Proteobacteria,431P8@68525|delta/epsilon subdivisions,2WWA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158348_k127_1440421_1	86106.I862_04540	3.248e-44	182.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,47EYD@766|Rickettsiales	766|Rickettsiales	M	Cell division protein FtsI penicillin-binding protein 2	pbpA1	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158348_k127_1440421_2	1121918.ARWE01000001_gene1048	5.242e-10	70.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42QYH@68525|delta/epsilon subdivisions,2WMXP@28221|Deltaproteobacteria,43SFP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158348_k127_1440421_0	1265505.ATUG01000003_gene182	5.111e-118	398.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_1442273_1	522772.Dacet_2370	1.789e-17	91.0	COG0718@1|root,COG0718@2|Bacteria,2GFU9@200930|Deferribacteres	200930|Deferribacteres	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158348_k127_1442273_0	1123508.JH636441_gene3070	4.309e-109	373.0	COG2812@1|root,COG2812@2|Bacteria,2IX1M@203682|Planctomycetes	203682|Planctomycetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158348_k127_1442273_2	1121033.AUCF01000027_gene2772	4.777e-11	63.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
SRR25158348_k127_1443394_1	886293.Sinac_4981	2.037e-81	286.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
SRR25158348_k127_1443394_0	517418.Ctha_0316	3.858e-87	319.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340,Gln_amidase
SRR25158348_k127_1443394_2	1122194.AUHU01000014_gene1158	1.737e-35	143.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158348_k127_1444382_3	1249480.B649_10560	0.0001656	54.0	COG1195@1|root,COG1361@1|root,COG3055@1|root,COG1195@2|Bacteria,COG1361@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Calx-beta,Kelch_1,Laminin_G_3
SRR25158348_k127_1444382_0	595460.RRSWK_04760	4.643e-07	60.0	COG2165@1|root,COG2165@2|Bacteria,2J14K@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158348_k127_1444382_1	1335757.SPICUR_07880	2.259e-05	58.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158348_k127_1444382_2	937777.Deipe_3812	0.0001414	53.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158348_k127_1453768_4	1123242.JH636436_gene134	6.515e-13	73.0	COG0585@1|root,COG0585@2|Bacteria,2IWTM@203682|Planctomycetes	203682|Planctomycetes	J	PFAM tRNA pseudouridine synthase D TruD	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
SRR25158348_k127_1453768_0	1521187.JPIM01000137_gene2066	1.873e-85	296.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158348_k127_1453768_1	391625.PPSIR1_21749	1.956e-37	147.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,434T9@68525|delta/epsilon subdivisions,2WZ49@28221|Deltaproteobacteria,2Z1AM@29|Myxococcales	28221|Deltaproteobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
SRR25158348_k127_1453768_3	1123242.JH636435_gene1455	2.267e-14	82.0	COG0265@1|root,COG0526@1|root,COG0265@2|Bacteria,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158348_k127_1453768_2	1210884.HG799463_gene10186	2.282e-22	100.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158348_k127_1453768_5	880073.Calab_2528	0.0005787	45.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	ugcG	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
SRR25158348_k127_145764_0	756067.MicvaDRAFT_0974	6.58e-142	462.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G13T@1117|Cyanobacteria,1HI4W@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
SRR25158348_k127_145764_1	1173027.Mic7113_0442	3.249e-37	160.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1G2MH@1117|Cyanobacteria,1H902@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SRR25158348_k127_1462068_0	374847.Kcr_0807	2.151e-13	82.0	COG0477@1|root,arCOG00130@2157|Archaea	374847.Kcr_0807|-	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1462397_1	1128421.JAGA01000002_gene62	7.327e-102	362.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158348_k127_1462397_0	330214.NIDE3974	1.973e-153	510.0	COG1012@1|root,COG1012@2|Bacteria,3J0YN@40117|Nitrospirae	40117|Nitrospirae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158348_k127_1463257_5	107635.AZUO01000001_gene47	0.0003059	46.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,36XM2@31993|Methylocystaceae	28211|Alphaproteobacteria	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158348_k127_1463257_4	553385.JEMF01000030_gene2523	9.645e-20	104.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XI8J@135619|Oceanospirillales	135619|Oceanospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158348_k127_1463257_2	247490.KSU1_B0637	4.809e-33	132.0	2E5IJ@1|root,3309Y@2|Bacteria,2J0P5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1463257_0	1121334.KB911077_gene2460	7.309e-148	487.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158348_k127_1463257_3	1123242.JH636435_gene1798	1.426e-24	116.0	COG0470@1|root,COG0470@2|Bacteria,2IZ3J@203682|Planctomycetes	203682|Planctomycetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158348_k127_1463257_1	340099.Teth39_2150	3.397e-42	164.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,42GBY@68295|Thermoanaerobacterales	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158348_k127_1465233_1	555779.Dthio_PD1504	1.109e-18	90.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_1465233_0	335543.Sfum_0741	2.718e-49	196.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2MQ91@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158348_k127_1471188_1	1121468.AUBR01000093_gene751	1.56e-15	81.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
SRR25158348_k127_1471188_0	247490.KSU1_B0390	3.343e-157	512.0	COG0029@1|root,COG0029@2|Bacteria,2IY30@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158348_k127_1472961_2	326427.Cagg_2931	6.942e-27	116.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
SRR25158348_k127_1472961_3	1379270.AUXF01000001_gene2168	2.235e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,1ZU2B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158348_k127_1472961_1	123214.PERMA_0284	3.168e-42	162.0	COG0461@1|root,COG0461@2|Bacteria,2G4DW@200783|Aquificae	200783|Aquificae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158348_k127_1472961_0	330214.NIDE2415	1.471e-47	178.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,3J0K5@40117|Nitrospirae	2|Bacteria	FP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ppx	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K07012	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000,ko02048	-	-	-	HD,Helicase_C,Ppx-GppA,Response_reg
SRR25158348_k127_1476051_2	345219.Bcoa_2679	2.938e-06	59.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
SRR25158348_k127_1476051_1	861299.J421_4225	1.42e-46	180.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
SRR25158348_k127_1476051_0	215803.DB30_5991	3.143e-104	358.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria,2YX8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158348_k127_1477410_0	247490.KSU1_C1126	5.634e-198	628.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158348_k127_1496798_1	237368.SCABRO_03505	3.738e-44	167.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158348_k127_1496798_2	756272.Plabr_2056	1.44e-40	153.0	COG0051@1|root,COG0051@2|Bacteria,2IZQR@203682|Planctomycetes	203682|Planctomycetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158348_k127_1496798_0	1294142.CINTURNW_0049	7.458e-195	629.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,36EHS@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158348_k127_1496798_5	714943.Mucpa_1394	0.000131	49.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP0D@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158348_k127_1496798_3	1173264.KI913949_gene1194	1.24e-18	98.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria,1HAKG@1150|Oscillatoriales	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1496798_4	448385.sce4880	5.03e-10	66.0	COG2194@1|root,COG2194@2|Bacteria,1Q2MI@1224|Proteobacteria,43885@68525|delta/epsilon subdivisions,2X3HW@28221|Deltaproteobacteria,2YW6A@29|Myxococcales	28221|Deltaproteobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1500584_1	1191523.MROS_2600	9.557e-15	81.0	COG1381@1|root,COG1381@2|Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158348_k127_1500584_0	429009.Adeg_1380	9.861e-128	419.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
SRR25158348_k127_1503922_0	575540.Isop_2743	8.66e-53	199.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158348_k127_1507134_1	272558.10176433	0.0004827	44.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus	91061|Bacilli	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158348_k127_1507134_0	1303518.CCALI_01897	5.767e-08	57.0	COG1595@1|root,COG1595@2|Bacteria	1303518.CCALI_01897|-	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158348_k127_1509321_0	1303518.CCALI_00947	5.691e-126	415.0	COG0162@1|root,COG0162@2|Bacteria	2|Bacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436,iLJ478.TM0478	S4,tRNA-synt_1b
SRR25158348_k127_1509579_1	1380391.JIAS01000015_gene42	1.218e-17	88.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158348_k127_1509579_0	1055815.AYYA01000050_gene2513	6.552e-21	96.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,3NSD9@468|Moraxellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158348_k127_1512101_2	1121428.DESHY_40062___1	1.524e-65	229.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158348_k127_1512101_1	1340493.JNIF01000003_gene2837	5.619e-83	282.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158348_k127_1512101_5	886293.Sinac_1543	1.127e-06	59.0	COG2314@1|root,COG2314@2|Bacteria,2J0G7@203682|Planctomycetes	203682|Planctomycetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1512101_4	247490.KSU1_D0953	3.252e-18	100.0	COG0681@1|root,COG0681@2|Bacteria,2IYWI@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158348_k127_1512101_0	575540.Isop_0731	1.133e-239	754.0	COG0481@1|root,COG0481@2|Bacteria,2IXI5@203682|Planctomycetes	203682|Planctomycetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158348_k127_1512101_3	1341151.ASZU01000008_gene1606	2.628e-25	110.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,27BN4@186824|Thermoactinomycetaceae	91061|Bacilli	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158348_k127_1513799_1	497964.CfE428DRAFT_2576	5.334e-07	61.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671,ko:K03673	ko01503,ko04621,ko05418,map01503,map04621,map05418	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	AhpC-TSA,Cleaved_Adhesin,DSBA,DUF4369,Redoxin,Thioredoxin,Thioredoxin_8
SRR25158348_k127_1513799_0	335543.Sfum_3671	4.387e-92	313.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158348_k127_1515563_1	639030.JHVA01000001_gene117	1.243e-91	311.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria,2JIDE@204432|Acidobacteriia	204432|Acidobacteriia	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158348_k127_1515563_4	1033738.CAEP01000143_gene1228	7.498e-05	54.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,26DCR@186818|Planococcaceae	91061|Bacilli	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	yyxA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_1515563_0	448385.sce0379	0.0	1341.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158348_k127_1518329_0	420246.GTNG_1341	3.066e-43	162.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1WFK4@129337|Geobacillus	91061|Bacilli	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158348_k127_1518329_1	926569.ANT_21890	3.82e-13	77.0	COG1796@1|root,COG1796@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158348_k127_152228_2	3711.Bra036428.1-P	2.224e-61	217.0	COG0334@1|root,KOG2250@2759|Eukaryota,37Q3I@33090|Viridiplantae,3G8ZE@35493|Streptophyta	35493|Streptophyta	E	Belongs to the Glu Leu Phe Val dehydrogenases family	GDH1	GO:0000166,GO:0003674,GO:0003824,GO:0004353,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006807,GO:0006950,GO:0006970,GO:0006995,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009267,GO:0009314,GO:0009416,GO:0009605,GO:0009628,GO:0009642,GO:0009646,GO:0009651,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016491,GO:0016638,GO:0016639,GO:0017076,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0051716,GO:0055114,GO:0071496,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901698	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158348_k127_152228_4	1123319.AUBE01000005_gene289	5.163e-05	52.0	COG2274@1|root,COG2274@2|Bacteria,2GNB5@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158348_k127_152228_0	391625.PPSIR1_03213	2.99e-101	353.0	COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158348_k127_152228_5	1384066.JAGT01000001_gene2619	0.0002385	49.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_152228_3	1123371.ATXH01000003_gene1949	1.82e-09	64.0	COG0265@1|root,COG0265@2|Bacteria,2GHRY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_152228_1	1121920.AUAU01000005_gene995	1.147e-63	242.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158348_k127_1528644_0	247490.KSU1_B0252	1.86e-47	192.0	COG0750@1|root,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158348_k127_1528644_1	1121430.JMLG01000001_gene2158	6.112e-39	149.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,260S5@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158348_k127_1532688_1	935837.JAEK01000039_gene3871	1.544e-07	53.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes,4IMUS@91061|Bacilli,1ZKVY@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1532688_0	197221.22296088	3.024e-16	93.0	COG0457@1|root,COG0457@2|Bacteria,1G07G@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
SRR25158348_k127_1533819_0	582515.KR51_00022780	9.656e-23	112.0	COG2251@1|root,COG2251@2|Bacteria,1G03D@1117|Cyanobacteria	1117|Cyanobacteria	S	RecB family	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,RNase_H_2
SRR25158348_k127_1534218_0	338963.Pcar_0642	2.191e-133	449.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,43T9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Metallo-beta-lactamase superfamily domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SRR25158348_k127_1534218_1	1268237.G114_10685	1.4e-19	95.0	COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S27W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1534876_3	926559.JoomaDRAFT_3653	9.858e-21	104.0	COG1874@1|root,COG4447@1|root,COG1874@2|Bacteria,COG4447@2|Bacteria,4PI15@976|Bacteroidetes,1I4K5@117743|Flavobacteriia	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158348_k127_1534876_4	1033743.CAES01000049_gene486	2.038e-19	100.0	COG4447@1|root,COG4447@2|Bacteria,1V10R@1239|Firmicutes,4IPNU@91061|Bacilli,27614@186822|Paenibacillaceae	91061|Bacilli	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR,Sortilin-Vps10
SRR25158348_k127_1534876_5	268739.Nmlp_2186	2.203e-07	60.0	COG1502@1|root,arCOG02041@2157|Archaea,2Y84U@28890|Euryarchaeota,23XBT@183963|Halobacteria	183963|Halobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	-
SRR25158348_k127_1534876_1	234267.Acid_7087	1.402e-71	255.0	COG1680@1|root,COG1680@2|Bacteria,3Y6F4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	3.4.16.4	ko:K18988	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase,DUF3471
SRR25158348_k127_1534876_2	404589.Anae109_1156	1.415e-36	150.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,42USC@68525|delta/epsilon subdivisions,2WQMY@28221|Deltaproteobacteria,2Z2ZG@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158348_k127_1534876_0	1158345.JNLL01000001_gene1734	1.305e-92	313.0	COG0191@1|root,COG0191@2|Bacteria,2G3VP@200783|Aquificae	200783|Aquificae	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158348_k127_1536162_2	1499967.BAYZ01000118_gene3248	9.125e-48	189.0	COG0845@1|root,COG0845@2|Bacteria,2NR8R@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
SRR25158348_k127_1536162_1	2002.JOEQ01000035_gene6692	1.588e-70	261.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4EGUE@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_1536162_0	1396418.BATQ01000030_gene5614	8.019e-85	305.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158348_k127_1536162_3	344747.PM8797T_26260	4.932e-15	78.0	COG0249@1|root,COG0249@2|Bacteria,2IXGV@203682|Planctomycetes	203682|Planctomycetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158348_k127_1536832_0	76114.c1A220	4.849e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KV0G@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158348_k127_1536832_1	1120948.KB903217_gene1454	3.312e-23	111.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4DYSG@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158348_k127_1536832_2	886293.Sinac_7077	5.844e-13	81.0	COG0500@1|root,COG2226@2|Bacteria,2IZZG@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158348_k127_1537097_2	1123242.JH636436_gene586	3.94e-36	146.0	COG0515@1|root,COG0515@2|Bacteria,2IXP6@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158348_k127_1537097_1	675635.Psed_0642	3.417e-59	215.0	COG1024@1|root,COG1024@2|Bacteria,2IEXB@201174|Actinobacteria,4E3W4@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA3_1	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158348_k127_1537097_0	648996.Theam_1729	2.178e-97	328.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158348_k127_153812_0	1210884.HG799466_gene12475	1.473e-46	174.0	COG0515@1|root,COG0515@2|Bacteria	1210884.HG799466_gene12475|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1540723_2	234267.Acid_1266	9.447e-54	206.0	COG1562@1|root,COG1562@2|Bacteria,3Y3YX@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158348_k127_1540723_1	204669.Acid345_1745	5.216e-74	273.0	COG1562@1|root,COG1562@2|Bacteria,3Y3ZV@57723|Acidobacteria,2JIMK@204432|Acidobacteriia	204432|Acidobacteriia	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR25158348_k127_1540723_3	886293.Sinac_0193	0.0004032	51.0	2BY8U@1|root,33NT9@2|Bacteria,2J1B8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1540723_0	1242864.D187_005528	8.414e-80	278.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,438ST@68525|delta/epsilon subdivisions,2X9CS@28221|Deltaproteobacteria,2YXPE@29|Myxococcales	28221|Deltaproteobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1540845_1	882.DVU_3197	8.434e-127	413.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158348_k127_1540845_0	1125863.JAFN01000001_gene929	9.702e-169	548.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158348_k127_1542378_0	246194.CHY_0290	1.607e-48	177.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158348_k127_1542378_1	879308.HMPREF9130_1933	1.563e-16	86.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158348_k127_1543186_0	644966.Tmar_0929	2.023e-105	359.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WCF1@538999|Clostridiales incertae sedis	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158348_k127_1549507_0	330214.NIDE3615	4.584e-108	368.0	COG2081@1|root,COG2081@2|Bacteria,3J12U@40117|Nitrospirae	40117|Nitrospirae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158348_k127_1549507_1	1379270.AUXF01000001_gene2745	1.224e-06	55.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158348_k127_1550428_6	1122915.AUGY01000001_gene7241	2.073e-05	48.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,26R4I@186822|Paenibacillaceae	91061|Bacilli	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
SRR25158348_k127_1550428_2	886293.Sinac_7098	1.45e-38	159.0	COG1657@1|root,COG1657@2|Bacteria,2IXAS@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
SRR25158348_k127_1550428_0	525904.Tter_0659	1.085e-90	314.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158348_k127_1550428_1	1173027.Mic7113_4125	1.019e-60	236.0	COG0079@1|root,COG0079@2|Bacteria,1FZV3@1117|Cyanobacteria,1H9BZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
SRR25158348_k127_1550428_4	638303.Thal_1363	2.976e-19	94.0	COG0071@1|root,COG0071@2|Bacteria,2G4AZ@200783|Aquificae	200783|Aquificae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158348_k127_1550428_3	1463854.JOHT01000009_gene1683	1.998e-19	99.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158348_k127_1550428_5	391037.Sare_1766	3.262e-15	78.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DA8Q@85008|Micromonosporales	201174|Actinobacteria	F	adenosine deaminase	add2	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158348_k127_1550694_2	234267.Acid_5820	2.541e-62	229.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158348_k127_1550694_1	234267.Acid_5819	9.616e-150	496.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158348_k127_1550694_0	247490.KSU1_C0312	0.0	1121.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158348_k127_1551242_5	1120946.AUBF01000004_gene1657	1.35e-32	132.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4D36U@85005|Actinomycetales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158348_k127_1551242_7	1142394.PSMK_11150	6.201e-06	51.0	COG1758@1|root,COG1758@2|Bacteria,2J0KS@203682|Planctomycetes	203682|Planctomycetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158348_k127_1551242_1	1118054.CAGW01000032_gene626	5.468e-50	187.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158348_k127_1551242_2	546414.Deide_01500	1.581e-49	192.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158348_k127_1551242_3	877414.ATWA01000003_gene340	2.766e-38	153.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,268GZ@186813|unclassified Clostridiales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158348_k127_1551242_0	237368.SCABRO_01493	7.867e-139	470.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158348_k127_1551242_6	234267.Acid_2431	1.422e-31	138.0	2F63Z@1|root,33YN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1551242_4	1210884.HG799468_gene13642	4.808e-36	139.0	COG2127@1|root,COG2127@2|Bacteria,2J06R@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the ClpS family	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158348_k127_1551242_8	215803.DB30_5550	2.09e-05	51.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,43BFU@68525|delta/epsilon subdivisions,2X5HG@28221|Deltaproteobacteria,2YUGC@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158348_k127_1551446_2	404589.Anae109_1279	2.574e-39	154.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158348_k127_1551446_0	880073.Calab_2684	1.89e-168	548.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158348_k127_1551446_1	404589.Anae109_1281	1.734e-55	207.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158348_k127_1558936_2	1123073.KB899242_gene1468	1.803e-17	93.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,1RZBM@1236|Gammaproteobacteria,1X4YD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158348_k127_1558936_1	552811.Dehly_0405	1.645e-33	132.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,34DCQ@301297|Dehalococcoidia	200795|Chloroflexi	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158348_k127_1558936_0	1444309.JAQG01000004_gene3626	3.124e-97	326.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,26QS0@186822|Paenibacillaceae	91061|Bacilli	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158348_k127_1561049_1	880073.Calab_0681	1.729e-65	249.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
SRR25158348_k127_1561049_2	1499967.BAYZ01000123_gene2552	6.314e-56	215.0	COG2208@1|root,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,SpoIIE,sCache_3_2
SRR25158348_k127_1561049_4	1191523.MROS_1859	4.776e-22	112.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2,SpoIIE
SRR25158348_k127_1561049_5	1499967.BAYZ01000123_gene2551	2.217e-21	98.0	COG1366@1|root,COG1366@2|Bacteria,2NRMX@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	btrV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158348_k127_1561049_3	1347368.HG964403_gene4038	8.352e-49	180.0	COG2032@1|root,COG2032@2|Bacteria,1V3HM@1239|Firmicutes,4IR7P@91061|Bacilli,1ZRS8@1386|Bacillus	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	-	-	-	-	-	-	-	-	-	-	Sod_Cu
SRR25158348_k127_1561049_7	1195246.AGRI_10021	5.104e-05	51.0	2DP8V@1|root,33122@2|Bacteria,1NC2I@1224|Proteobacteria,1SCSG@1236|Gammaproteobacteria,46BAE@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1561049_0	945713.IALB_2724	9.672e-263	822.0	COG2192@1|root,COG2192@2|Bacteria	2|Bacteria	O	nodulation	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158348_k127_1561049_6	886293.Sinac_7435	1.395e-06	51.0	2EGPU@1|root,32K36@2|Bacteria,2J1G1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1562633_1	1499967.BAYZ01000061_gene5973	2.966e-144	469.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1,2.2.1.8	ko:K00600,ko:K18847	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158348_k127_1562633_0	247490.KSU1_D0628	7.153e-161	522.0	COG0138@1|root,COG0138@2|Bacteria,2IXB5@203682|Planctomycetes	203682|Planctomycetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158348_k127_1562633_3	1123508.JH636452_gene7003	2.668e-52	187.0	COG0251@1|root,COG0251@2|Bacteria,2J0VA@203682|Planctomycetes	203682|Planctomycetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158348_k127_1562633_2	682795.AciX8_1432	6.333e-102	344.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_1562633_4	886293.Sinac_1570	3.079e-38	147.0	COG4198@1|root,COG4198@2|Bacteria,2IX7C@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158348_k127_1568820_2	742742.HMPREF9452_00793	4.224e-10	61.0	COG0473@1|root,COG0473@2|Bacteria,2IAD3@201174|Actinobacteria,4CU7N@84998|Coriobacteriia	84998|Coriobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158348_k127_1568820_0	404589.Anae109_0363	3.239e-101	338.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2YV2A@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
SRR25158348_k127_1568820_1	1487953.JMKF01000052_gene1656	8.618e-37	146.0	COG4122@1|root,COG4122@2|Bacteria,1G2Y6@1117|Cyanobacteria,1H74J@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158348_k127_1571019_4	649638.Trad_0864	6.315e-20	95.0	COG0424@1|root,COG0424@2|Bacteria,1WK7N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158348_k127_1571019_1	1323663.AROI01000004_gene2093	2.299e-32	142.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158348_k127_1571019_2	583355.Caka_1765	8.55e-22	101.0	29Q4T@1|root,334S3@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_1571019_0	945713.IALB_1689	3.691e-65	234.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158348_k127_1571019_3	1173264.KI913949_gene3679	1.488e-21	95.0	COG1598@1|root,COG1598@2|Bacteria,1G9MA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158348_k127_1575314_3	1033734.CAET01000062_gene1965	5.642e-42	176.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,1ZB1C@1386|Bacillus	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	ywrF	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158348_k127_1575314_2	404589.Anae109_3587	2.064e-52	193.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158348_k127_1575314_4	1278073.MYSTI_00286	1.056e-22	108.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158348_k127_1575314_1	671143.DAMO_3119	5.028e-53	198.0	COG1893@1|root,COG1893@2|Bacteria,2NPMG@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158348_k127_1575314_0	1382304.JNIL01000001_gene2282	3.508e-143	466.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,2782J@186823|Alicyclobacillaceae	91061|Bacilli	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158348_k127_1582965_3	215803.DB30_5852	3.046e-09	71.0	COG3325@1|root,COG3391@1|root,COG4412@1|root,COG3325@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36,REJ
SRR25158348_k127_1582965_1	1191523.MROS_2048	4.417e-25	123.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
SRR25158348_k127_1582965_2	472759.Nhal_1087	6.071e-25	123.0	COG0737@1|root,COG0737@2|Bacteria,1RFNB@1224|Proteobacteria	1224|Proteobacteria	C	oxidation-reduction process	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR25158348_k127_1582965_0	1242864.D187_005725	2.888e-36	147.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT,Paired_CXXCH_1
SRR25158348_k127_1583525_1	237368.SCABRO_03514	4.56e-76	271.0	COG0653@1|root,COG0653@2|Bacteria,2IXIT@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158348_k127_1583525_0	344747.PM8797T_01709	8.445e-82	293.0	COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes	203682|Planctomycetes	M	transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158348_k127_1583525_2	886293.Sinac_2787	5.775e-10	72.0	COG1595@1|root,COG1595@2|Bacteria,2IYTY@203682|Planctomycetes	203682|Planctomycetes	K	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10,Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1583525_3	268407.PWYN_24770	6.731e-09	69.0	COG1595@1|root,COG1595@2|Bacteria,1V7S9@1239|Firmicutes,4HJ5E@91061|Bacilli,26UZY@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW9	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1584289_0	247490.KSU1_B0576	2.263e-115	382.0	COG0482@1|root,COG0482@2|Bacteria,2IXFF@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158348_k127_1584748_6	1459636.NTE_01538	9.654e-36	145.0	COG0328@1|root,arCOG02942@2157|Archaea,41SWJ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	RNase H	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158348_k127_1584748_8	682795.AciX8_2663	4.418e-18	86.0	COG2128@1|root,COG2128@2|Bacteria,3Y8IA@57723|Acidobacteria,2JNES@204432|Acidobacteriia	204432|Acidobacteriia	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158348_k127_1584748_9	293826.Amet_3687	1.099e-16	92.0	COG2128@1|root,COG2128@2|Bacteria,1VQME@1239|Firmicutes,24V56@186801|Clostridia	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158348_k127_1584748_2	1174528.JH992898_gene3679	7.608e-47	174.0	COG0662@1|root,COG0662@2|Bacteria,1GAI7@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158348_k127_1584748_5	1206741.BAFX01000061_gene5145	2.507e-36	144.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria,4G0IN@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158348_k127_1584748_7	234267.Acid_3395	9.346e-22	100.0	2FGUY@1|root,348Q9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1584748_1	1278073.MYSTI_05137	3.597e-75	262.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,42RA9@68525|delta/epsilon subdivisions,2WQIZ@28221|Deltaproteobacteria,2YWBB@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158348_k127_1584748_3	204669.Acid345_1871	2.869e-43	172.0	COG0311@1|root,COG0311@2|Bacteria,3Y4GN@57723|Acidobacteria,2JJ3V@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158348_k127_1584748_0	1303518.CCALI_02632	7.425e-135	437.0	COG0214@1|root,COG0214@2|Bacteria	2|Bacteria	H	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158348_k127_1584748_4	1227488.C477_08463	2.179e-39	151.0	COG3217@1|root,arCOG04766@2157|Archaea,2Y7HS@28890|Euryarchaeota,241HM@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158348_k127_1584748_10	1265505.ATUG01000003_gene847	4.9e-08	57.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,42NNG@68525|delta/epsilon subdivisions,2WPRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158348_k127_1585627_7	1270193.JARP01000007_gene207	3.788e-12	79.0	COG4733@1|root,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1I3YW@117743|Flavobacteriia,2NUAW@237|Flavobacterium	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1585627_6	459349.CLOAM0061	1.156e-18	100.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
SRR25158348_k127_1585627_0	398767.Glov_3272	8.918e-118	390.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158348_k127_1585627_1	237368.SCABRO_03082	1.022e-101	340.0	COG0463@1|root,COG0463@2|Bacteria,2IXAV@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158348_k127_1585627_3	452637.Oter_1412	1.334e-72	267.0	COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,3K7UM@414999|Opitutae	74201|Verrucomicrobia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158348_k127_1585627_2	555088.DealDRAFT_1940	1.696e-93	325.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,42KNT@68298|Syntrophomonadaceae	186801|Clostridia	M	Male sterility protein	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158348_k127_1585627_4	1304874.JAFY01000002_gene1049	6.808e-50	199.0	COG0726@1|root,COG0726@2|Bacteria,3TAKV@508458|Synergistetes	508458|Synergistetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158348_k127_1585627_5	596154.Alide2_3510	1.142e-47	188.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,4ACZ5@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158348_k127_1589161_2	221288.JH992901_gene5734	2.47e-54	194.0	COG0055@1|root,COG0055@2|Bacteria,1G1BK@1117|Cyanobacteria,1JJZ4@1189|Stigonemataceae	1117|Cyanobacteria	C	ATP synthase alpha/beta family, nucleotide-binding domain	atpD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158348_k127_1589161_1	643648.Slip_2283	3.261e-69	244.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,42K9T@68298|Syntrophomonadaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158348_k127_1589161_0	246194.CHY_2547	4.215e-218	686.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,42F4E@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158348_k127_1589161_3	290318.Cvib_1740	4.933e-06	49.0	COG0712@1|root,COG0712@2|Bacteria,1FE0N@1090|Chlorobi	1090|Chlorobi	F	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158348_k127_1590070_2	438753.AZC_3187	1.04e-46	180.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,3F0Z5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158348_k127_1590070_0	1192034.CAP_0946	6.205e-83	290.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2YYYW@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158348_k127_1590070_3	1380347.JNII01000005_gene3068	9.194e-20	100.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158348_k127_1590070_1	266117.Rxyl_2275	3.739e-57	209.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria,4CT60@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1590070_4	502025.Hoch_5093	5.834e-17	83.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158348_k127_1591059_4	522772.Dacet_0811	8.981e-11	63.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,2GG8Y@200930|Deferribacteres	200930|Deferribacteres	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158348_k127_1591059_2	1437882.AZRU01000067_gene5441	4.619e-37	145.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,1YH64@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158348_k127_1591059_3	861299.J421_1850	7.001e-37	145.0	2CN2H@1|root,32SG5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1591059_0	247490.KSU1_B0239	3.232e-112	377.0	COG1160@1|root,COG1160@2|Bacteria,2IWXY@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158348_k127_1591059_1	487796.Flav2ADRAFT_0382	2.208e-74	269.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158348_k127_1595612_2	1242864.D187_007187	6.867e-46	174.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WMDZ@28221|Deltaproteobacteria,2YV35@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158348_k127_1595612_3	926550.CLDAP_09900	4.953e-27	127.0	COG3391@1|root,COG3391@2|Bacteria,2G9E4@200795|Chloroflexi	200795|Chloroflexi	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1595612_1	926569.ANT_11190	4.779e-94	311.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158348_k127_1595612_0	1125863.JAFN01000001_gene2637	1.513e-224	722.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158348_k127_1595612_4	314230.DSM3645_11906	2.048e-07	57.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DUF4038,DUF5060,DUF721
SRR25158348_k127_1597319_2	1356854.N007_04370	2.377e-07	54.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HC5M@91061|Bacilli,27958@186823|Alicyclobacillaceae	91061|Bacilli	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,Sigma54_activat
SRR25158348_k127_1597319_1	575540.Isop_0409	3.364e-30	133.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
SRR25158348_k127_1597319_0	3218.PP1S46_300V6.1	2.643e-102	344.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158348_k127_1598180_2	575540.Isop_1256	1.251e-28	117.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Ribonuc_L-PSP
SRR25158348_k127_1598180_0	1304880.JAGB01000002_gene2320	3.588e-88	309.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SRR25158348_k127_1598180_1	1379281.AVAG01000027_gene1687	6.105e-59	229.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2M7VK@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158348_k127_160324_3	448385.sce6512	4.08e-69	245.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,43BFU@68525|delta/epsilon subdivisions,2X5HG@28221|Deltaproteobacteria,2YUGC@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158348_k127_160324_1	215803.DB30_1185	3.005e-109	364.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158348_k127_160324_5	1185653.A1A1_11902	5.292e-48	179.0	COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,26FPK@186818|Planococcaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	p20	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158348_k127_160324_0	521674.Plim_2688	3.647e-149	483.0	COG1271@1|root,COG1271@2|Bacteria,2IXYC@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome bd-type quinol oxidase subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158348_k127_160324_2	314230.DSM3645_05440	1.261e-98	338.0	COG1294@1|root,COG1294@2|Bacteria,2IZKX@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome bd-type quinol oxidase, subunit 2	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158348_k127_160324_4	640081.Dsui_3021	1.249e-52	197.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,2VPJH@28216|Betaproteobacteria,2KYAA@206389|Rhodocyclales	206389|Rhodocyclales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158348_k127_1611496_4	1037409.BJ6T_37230	1.168e-14	87.0	COG2227@1|root,COG2227@2|Bacteria,1PEZH@1224|Proteobacteria,2UN3W@28211|Alphaproteobacteria,3K23V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158348_k127_1611496_3	331678.Cphamn1_2145	1.05e-70	252.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158348_k127_1611496_0	864702.OsccyDRAFT_3182	1.505e-120	414.0	COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1H8D4@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_1611496_2	471854.Dfer_2209	6.201e-80	275.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,Methyltransf_21,Methyltransf_24
SRR25158348_k127_1611496_5	330084.JNYZ01000017_gene5190	7.517e-05	55.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria,4DYQK@85010|Pseudonocardiales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
SRR25158348_k127_1611496_1	1500304.JQKY01000019_gene628	8.625e-118	389.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,4BA1X@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158348_k127_1612719_0	290397.Adeh_1808	8.818e-205	657.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YWBK@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158348_k127_1612719_2	1235457.C404_24005	1.126e-46	192.0	COG1247@1|root,COG1247@2|Bacteria,1QUGY@1224|Proteobacteria,2WH72@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158348_k127_1612719_1	1210884.HG799470_gene14472	3.376e-55	198.0	2E0D2@1|root,32VZX@2|Bacteria,2J33D@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1613273_0	1121438.JNJA01000004_gene646	2.176e-29	136.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MG1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
SRR25158348_k127_1613273_1	1120972.AUMH01000007_gene1721	1.984e-14	83.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158348_k127_1614636_4	1341155.FSS13T_09100	0.0004135	46.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158348_k127_1614636_0	1123508.JH636441_gene3274	1.764e-63	235.0	COG0063@1|root,COG0063@2|Bacteria,2IYWH@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
SRR25158348_k127_1614636_3	443144.GM21_3173	7.047e-16	90.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
SRR25158348_k127_1614636_1	1379698.RBG1_1C00001G0780	2.521e-41	169.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
SRR25158348_k127_1614636_5	161156.JQKW01000006_gene1251	0.0009045	52.0	2C2QQ@1|root,32RAW@2|Bacteria	2|Bacteria	-	-	omcX	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1614636_2	484770.UFO1_2516	3.497e-31	130.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4H3RE@909932|Negativicutes	909932|Negativicutes	D	TIGRFAM stage V sporulation protein E, cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158348_k127_161511_0	1191523.MROS_0135	5.007e-143	465.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158348_k127_161511_1	404380.Gbem_3913	4.441e-91	319.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158348_k127_1622074_3	402626.Rpic_1260	0.0004248	49.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2VNWW@28216|Betaproteobacteria,1KHHM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
SRR25158348_k127_1622074_1	1007105.PT7_3425	5.078e-36	143.0	COG1309@1|root,COG1309@2|Bacteria,1QIJW@1224|Proteobacteria,2VWBG@28216|Betaproteobacteria,3T83S@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158348_k127_1622074_2	237368.SCABRO_00501	3.533e-27	115.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158348_k127_1622074_0	886293.Sinac_5689	4.37e-165	537.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2IY3H@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158348_k127_1625916_1	323259.Mhun_0597	4.156e-53	207.0	COG3291@1|root,arCOG02559@1|root,arCOG06792@1|root,arCOG02508@2157|Archaea,arCOG02559@2157|Archaea,arCOG06792@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158348_k127_1625916_0	555088.DealDRAFT_0271	8.707e-96	329.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42KYM@68298|Syntrophomonadaceae	186801|Clostridia	H	Aminotransferase class-V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158348_k127_1625916_2	572477.Alvin_1911	1.651e-23	115.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1WYXG@135613|Chromatiales	135613|Chromatiales	P	Divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158348_k127_1628558_0	1278073.MYSTI_08100	2.41e-43	179.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pknB	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
SRR25158348_k127_1628954_0	886293.Sinac_1731	5.189e-112	367.0	COG0476@1|root,COG0476@2|Bacteria,2IY9K@203682|Planctomycetes	203682|Planctomycetes	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158348_k127_1628954_1	1382359.JIAL01000001_gene624	1.451e-104	348.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158348_k127_1631553_1	583355.Caka_0888	6.012e-11	74.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	hhoA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_1631553_0	1254432.SCE1572_51965	2.35e-13	79.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria,2YVMW@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
SRR25158348_k127_1635904_1	767817.Desgi_0218	1.39e-51	195.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1V0H0@1239|Firmicutes,25C7Q@186801|Clostridia,263NU@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158348_k127_1635904_0	1121413.JMKT01000015_gene305	2.133e-67	249.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,42R9E@68525|delta/epsilon subdivisions,2WNRJ@28221|Deltaproteobacteria,2MAXH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158348_k127_1635904_3	448385.sce1728	4.514e-21	97.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2Z0Z9@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158348_k127_1635904_2	1278073.MYSTI_08053	1.284e-46	174.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QX74@1224|Proteobacteria,43AJN@68525|delta/epsilon subdivisions,2X5ZV@28221|Deltaproteobacteria,2YYZX@29|Myxococcales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158348_k127_1637731_0	1123371.ATXH01000003_gene1949	1.107e-62	226.0	COG0265@1|root,COG0265@2|Bacteria,2GHRY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_1637731_1	234267.Acid_5134	5.51e-26	121.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Q6@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1637731_2	234267.Acid_5135	3.206e-17	83.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Z3@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_1639454_2	1223523.H340_04694	4.366e-27	117.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_1639454_0	926550.CLDAP_07190	1.149e-47	183.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
SRR25158348_k127_1639454_3	518766.Rmar_2018	1.855e-10	73.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
SRR25158348_k127_1639454_4	935836.JAEL01000170_gene4190	8.218e-09	64.0	COG2846@1|root,COG2846@2|Bacteria,1UYJV@1239|Firmicutes,4HE93@91061|Bacilli,1ZE2Y@1386|Bacillus	91061|Bacilli	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	scdA	GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SRR25158348_k127_1639454_1	247490.KSU1_B0185	5.232e-28	124.0	COG2846@1|root,COG2846@2|Bacteria,2J23U@203682|Planctomycetes	203682|Planctomycetes	D	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,NnrS
SRR25158348_k127_1641758_0	1123242.JH636435_gene894	9.028e-241	754.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
SRR25158348_k127_1643603_0	243231.GSU1012	6.486e-39	156.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
SRR25158348_k127_1643794_2	500632.CLONEX_04180	4.019e-15	79.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158348_k127_1643794_0	330214.NIDE0820	1.445e-44	167.0	COG0780@1|root,COG0780@2|Bacteria,3J0R4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158348_k127_1643794_1	471854.Dfer_2527	3.107e-34	146.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
SRR25158348_k127_1644942_1	857087.Metme_1326	2.512e-07	58.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,1S35N@1236|Gammaproteobacteria,1XH03@135618|Methylococcales	135618|Methylococcales	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
SRR25158348_k127_1644942_0	1123070.KB899266_gene2510	5.544e-51	201.0	2F1T9@1|root,33UTC@2|Bacteria	2|Bacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR25158348_k127_1644942_2	1267533.KB906737_gene1719	1.77e-06	62.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria,2JM74@204432|Acidobacteriia	204432|Acidobacteriia	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_6,TPR_8
SRR25158348_k127_1645049_0	1095769.CAHF01000010_gene1334	7.996e-37	149.0	2A69T@1|root,30V2E@2|Bacteria,1P1HW@1224|Proteobacteria,2W4YP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158348_k127_1645049_1	1095769.CAHF01000010_gene1334	1.169e-33	139.0	2A69T@1|root,30V2E@2|Bacteria,1P1HW@1224|Proteobacteria,2W4YP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158348_k127_1653363_0	330214.NIDE1932	1.552e-257	807.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	40117|Nitrospirae	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158348_k127_1653363_1	644966.Tmar_1459	1.407e-80	279.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ,NTP_transf_3
SRR25158348_k127_1653363_2	1234364.AMSF01000061_gene2084	8.233e-07	60.0	COG0793@1|root,COG0793@2|Bacteria,1N4T9@1224|Proteobacteria,1SE36@1236|Gammaproteobacteria,1X70X@135614|Xanthomonadales	135614|Xanthomonadales	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ_2
SRR25158348_k127_1655473_0	582744.Msip34_1178	2.59e-171	559.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIGR@28216|Betaproteobacteria,2KKNQ@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158348_k127_1655473_1	330214.NIDE1932	2.028e-110	364.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	40117|Nitrospirae	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158348_k127_1656407_0	237368.SCABRO_01465	2.402e-86	296.0	COG0472@1|root,COG0472@2|Bacteria,2IXU1@203682|Planctomycetes	203682|Planctomycetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158348_k127_1656407_2	264198.Reut_A2925	1.084e-14	84.0	2E7H0@1|root,331ZM@2|Bacteria,1NAWU@1224|Proteobacteria,2W5VE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
SRR25158348_k127_1656407_3	552811.Dehly_1377	2.859e-09	67.0	COG4818@1|root,COG4818@2|Bacteria,2G9D6@200795|Chloroflexi,34DD3@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SRR25158348_k127_1656407_1	1047013.AQSP01000111_gene1665	1.071e-41	158.0	COG0039@1|root,COG0039@2|Bacteria,2NNY8@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158348_k127_1656415_0	663610.JQKO01000018_gene3026	5.89e-107	353.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,3N9K5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	AcrB/AcrD/AcrF family	cnrA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR25158348_k127_1656415_1	472759.Nhal_1651	9.37e-58	220.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,1S3EC@1236|Gammaproteobacteria,1X29E@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SRR25158348_k127_1656415_2	1157708.KB907450_gene6603	2.925e-22	110.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,2VIMD@28216|Betaproteobacteria,4AA6D@80864|Comamonadaceae	28216|Betaproteobacteria	MU	PFAM Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SRR25158348_k127_1656415_3	195250.CM001776_gene1647	5.534e-09	65.0	COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1GED2@1117|Cyanobacteria,1H2ZS@1129|Synechococcus	1117|Cyanobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158348_k127_1658178_0	1379698.RBG1_1C00001G0614	3.188e-219	701.0	COG1505@1|root,COG1505@2|Bacteria,2NNUB@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158348_k127_1658178_1	886293.Sinac_5336	1.298e-58	209.0	COG0855@1|root,COG0855@2|Bacteria,2IWVK@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158348_k127_1660468_0	290397.Adeh_3929	6.297e-41	153.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158348_k127_1660468_3	34740.HMEL014202-PA	2.397e-06	56.0	COG0753@1|root,KOG0047@2759|Eukaryota,38BMC@33154|Opisthokonta,3BFAV@33208|Metazoa,3CSMT@33213|Bilateria,41UVT@6656|Arthropoda,3SHKQ@50557|Insecta,441FJ@7088|Lepidoptera	33208|Metazoa	P	Catalase	-	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
SRR25158348_k127_1660468_1	1134474.O59_001444	3.576e-39	166.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria,1FGY3@10|Cellvibrio	1236|Gammaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	ppkA	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,PEGA,Pkinase
SRR25158348_k127_1660468_2	522306.CAP2UW1_2609	1.041e-18	96.0	COG1192@1|root,COG1357@1|root,COG1787@1|root,COG2319@1|root,COG5635@1|root,COG1192@2|Bacteria,COG1357@2|Bacteria,COG1787@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
SRR25158348_k127_1663810_1	1201288.M900_0358	6.363e-15	81.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,42VAD@68525|delta/epsilon subdivisions,2WRMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
SRR25158348_k127_1663810_3	1163617.SCD_n02614	4.294e-08	59.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
SRR25158348_k127_1663810_0	644966.Tmar_1413	5.09e-103	345.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WCYS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158348_k127_1663810_2	290397.Adeh_1557	1.025e-12	69.0	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158348_k127_1664218_0	502025.Hoch_4258	1.46e-152	500.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,437TW@68525|delta/epsilon subdivisions,2X33B@28221|Deltaproteobacteria,2YU23@29|Myxococcales	28221|Deltaproteobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRR25158348_k127_1670438_1	1125863.JAFN01000001_gene1921	4.106e-14	78.0	COG0296@1|root,COG0296@2|Bacteria,1NEFK@1224|Proteobacteria,42VRH@68525|delta/epsilon subdivisions,2WRD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
SRR25158348_k127_1670438_0	1128421.JAGA01000003_gene3735	3.563e-21	100.0	COG1595@1|root,COG1595@2|Bacteria,2NR8H@2323|unclassified Bacteria	2|Bacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158348_k127_1675100_1	237368.SCABRO_03707	9.476e-95	321.0	COG0195@1|root,COG0195@2|Bacteria,2IWY3@203682|Planctomycetes	203682|Planctomycetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SRR25158348_k127_1675100_2	1122164.JHWF01000047_gene696	0.0001312	47.0	2AQ08@1|root,31F55@2|Bacteria,1QCIT@1224|Proteobacteria,1T89I@1236|Gammaproteobacteria,1JGET@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1675100_0	1449049.JONW01000005_gene1170	8.393e-122	396.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,2TS8X@28211|Alphaproteobacteria,2KIYB@204458|Caulobacterales	204458|Caulobacterales	E	Glutaminase	-	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
SRR25158348_k127_1677371_0	391625.PPSIR1_04398	1.122e-30	125.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158348_k127_1677371_1	543526.Htur_0401	5.039e-07	62.0	arCOG02980@1|root,arCOG02980@2157|Archaea,2XTKT@28890|Euryarchaeota,23SJA@183963|Halobacteria	183963|Halobacteria	S	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1677479_1	379066.GAU_1412	6.856e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
SRR25158348_k127_1677479_0	1125863.JAFN01000001_gene3280	1.168e-69	257.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PJW@68525|delta/epsilon subdivisions,2WJQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
SRR25158348_k127_1679788_1	658187.LDG_7093	7.699e-56	211.0	COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T4YK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158348_k127_1679788_2	1449126.JQKL01000005_gene876	5.347e-32	129.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
SRR25158348_k127_1679788_0	661478.OP10G_4764	5.63e-166	528.0	COG0055@1|root,COG0055@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158348_k127_1681965_1	485917.Phep_3604	3.74e-25	110.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1IQMF@117747|Sphingobacteriia	976|Bacteroidetes	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158348_k127_1681965_2	443144.GM21_1796	1.022e-24	115.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42UTC@68525|delta/epsilon subdivisions,2WR18@28221|Deltaproteobacteria,43SEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:TPM	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158348_k127_1681965_0	335543.Sfum_1996	3.565e-40	152.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR25158348_k127_1687741_5	760568.Desku_1736	0.0008199	48.0	COG2232@1|root,COG2232@2|Bacteria,1TPT6@1239|Firmicutes,24DWY@186801|Clostridia	186801|Clostridia	S	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,HAD_2
SRR25158348_k127_1687741_0	502025.Hoch_6045	1.965e-39	168.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1Q53R@1224|Proteobacteria,430W1@68525|delta/epsilon subdivisions,2WVP7@28221|Deltaproteobacteria,2YWDG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SRR25158348_k127_1687741_1	243090.RB7926	1.584e-33	138.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158348_k127_1687741_4	794903.OPIT5_03035	1.993e-06	60.0	COG5338@1|root,COG5338@2|Bacteria,46XUT@74201|Verrucomicrobia,3K8B8@414999|Opitutae	414999|Opitutae	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
SRR25158348_k127_1687741_2	887898.HMPREF0551_2405	8.103e-28	124.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,1KGRE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	polysaccharide export	epsE	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158348_k127_1687741_3	756272.Plabr_3735	2.333e-13	82.0	2ABPF@1|root,3115E@2|Bacteria,2J40E@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1689076_0	748280.NH8B_2766	8.984e-286	904.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158348_k127_1689076_1	1127692.HMPREF9075_00760	1.724e-73	260.0	COG0639@1|root,COG0639@2|Bacteria,4NME8@976|Bacteroidetes,1I2NG@117743|Flavobacteriia,1ERMH@1016|Capnocytophaga	976|Bacteroidetes	T	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158348_k127_1689076_2	671143.DAMO_1259	4.065e-38	150.0	COG1309@1|root,COG1309@2|Bacteria,2NQ8G@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	MA20_16815	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158348_k127_1696910_0	215803.DB30_3102	7.119e-65	228.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,42SUN@68525|delta/epsilon subdivisions,2WPCU@28221|Deltaproteobacteria,2YXKB@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158348_k127_1696910_1	1353537.TP2_08935	2.849e-28	128.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2XN3R@285107|Thioclava	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158348_k127_1697927_0	344747.PM8797T_05165	1.126e-73	259.0	COG0142@1|root,COG0142@2|Bacteria,2IXUE@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158348_k127_1697927_1	696369.KI912183_gene2043	1.57e-09	69.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_1700134_3	945713.IALB_3109	1.647e-17	94.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158348_k127_1700134_4	909663.KI867150_gene2891	0.0001521	55.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
SRR25158348_k127_1700134_0	247490.KSU1_C1002	6.577e-88	297.0	COG0020@1|root,COG0020@2|Bacteria,2IX6Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158348_k127_1700134_2	278963.ATWD01000001_gene1951	1.221e-25	120.0	COG4589@1|root,COG4589@2|Bacteria,3Y4VA@57723|Acidobacteria,2JJIU@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158348_k127_1700134_1	237368.SCABRO_01970	2.357e-87	299.0	COG1702@1|root,COG1702@2|Bacteria,2IXBB@203682|Planctomycetes	203682|Planctomycetes	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158348_k127_1701547_0	1232410.KI421413_gene952	4.532e-254	806.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,4378Y@68525|delta/epsilon subdivisions,2X2C1@28221|Deltaproteobacteria,43UD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158348_k127_1701547_4	926550.CLDAP_11760	2.536e-14	76.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi	200795|Chloroflexi	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158348_k127_1701547_2	1242864.D187_004787	5.303e-118	390.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,433XH@68525|delta/epsilon subdivisions,2X2FU@28221|Deltaproteobacteria,2YXR6@29|Myxococcales	28221|Deltaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158348_k127_1701547_1	1254432.SCE1572_08690	9.089e-168	541.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,43AKF@68525|delta/epsilon subdivisions,2X60H@28221|Deltaproteobacteria,2YZ4M@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158348_k127_1701547_3	1123508.JH636453_gene5800	6.521e-15	85.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158348_k127_1701603_2	247490.KSU1_B0323	8.152e-70	239.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158348_k127_1701603_0	926560.KE387023_gene2473	2.096e-227	739.0	COG3280@1|root,COG3280@2|Bacteria,1WJD0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	malto-oligosyltrehalose synthase	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158348_k127_1701603_1	1408419.JHYG01000003_gene362	1.625e-105	359.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,2JPVA@204441|Rhodospirillales	204441|Rhodospirillales	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158348_k127_1702282_0	1537915.JU57_10085	3.149e-14	82.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2YN9P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158348_k127_1708563_3	555088.DealDRAFT_1109	3.154e-69	264.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42JNC@68298|Syntrophomonadaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158348_k127_1708563_1	404589.Anae109_2774	2.997e-107	359.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158348_k127_1708563_2	234267.Acid_2875	5.908e-106	356.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158348_k127_1708563_4	1122182.KB903813_gene2710	2.077e-63	227.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4D8E9@85008|Micromonosporales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158348_k127_1708563_0	1254432.SCE1572_12170	2.363e-139	486.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
SRR25158348_k127_1708563_5	502025.Hoch_5093	6.211e-24	108.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158348_k127_1709704_0	1120705.FG95_03255	1.006e-75	257.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,2K6EE@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158348_k127_1709704_5	521674.Plim_0632	2.369e-15	90.0	COG2304@1|root,COG2304@2|Bacteria,2IZSI@203682|Planctomycetes	203682|Planctomycetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
SRR25158348_k127_1709704_2	502025.Hoch_2499	9.522e-54	206.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158348_k127_1709704_4	945713.IALB_2435	4.43e-16	83.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
SRR25158348_k127_1709704_1	945713.IALB_2434	9.438e-64	223.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158348_k127_1709704_3	945713.IALB_2433	6.574e-46	171.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
SRR25158348_k127_171253_1	640081.Dsui_3202	5.912e-68	245.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria	1224|Proteobacteria	S	peptidase m48, ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_2,TPR_8
SRR25158348_k127_171253_2	471853.Bcav_3749	3.172e-26	119.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158348_k127_171253_0	1173027.Mic7113_2544	3.092e-87	301.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Ribonuclease BN-like family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158348_k127_1716174_1	246197.MXAN_1970	1.536e-67	243.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42SU3@68525|delta/epsilon subdivisions,2WP9X@28221|Deltaproteobacteria,2YVJF@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
SRR25158348_k127_1716174_0	1267535.KB906767_gene604	1.972e-283	902.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3Y37Y@57723|Acidobacteria,2JI9E@204432|Acidobacteriia	204432|Acidobacteriia	E	Vitamin B12 dependent methionine synthase activation	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158348_k127_1720173_0	1250278.JQNQ01000001_gene2526	1.895e-81	277.0	COG1043@1|root,COG1043@2|Bacteria,4NJC7@976|Bacteroidetes,1I24X@117743|Flavobacteriia	976|Bacteroidetes	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158348_k127_1720173_2	935557.ATYB01000008_gene5240	1.119e-51	196.0	COG0458@1|root,COG0458@2|Bacteria,1RJ88@1224|Proteobacteria,2UB8A@28211|Alphaproteobacteria,4BGH6@82115|Rhizobiaceae	28211|Alphaproteobacteria	EF	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
SRR25158348_k127_1720173_1	379066.GAU_2048	1.103e-60	214.0	COG0605@1|root,COG0605@2|Bacteria,1ZT7S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158348_k127_1729421_1	1123242.JH636434_gene4330	4.996e-35	139.0	COG0768@1|root,COG0768@2|Bacteria,2IXAE@203682|Planctomycetes	203682|Planctomycetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158348_k127_1729421_0	247490.KSU1_C0166	2.574e-63	237.0	COG0772@1|root,COG0772@2|Bacteria,2IZRI@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158348_k127_1729421_2	1031288.AXAA01000013_gene527	1.387e-33	142.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,36EP7@31979|Clostridiaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158348_k127_1744997_0	1304880.JAGB01000002_gene1934	2.677e-149	489.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158348_k127_175701_0	530564.Psta_1035	2.553e-114	381.0	COG1055@1|root,COG1055@2|Bacteria,2IY4X@203682|Planctomycetes	203682|Planctomycetes	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
SRR25158348_k127_175701_1	247490.KSU1_C0114	1.114e-08	68.0	COG3147@1|root,COG3147@2|Bacteria,2IXFB@203682|Planctomycetes	203682|Planctomycetes	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_181200_0	880073.Calab_3732	1.23e-82	286.0	COG1611@1|root,COG1611@2|Bacteria,2NP7M@2323|unclassified Bacteria	2|Bacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158348_k127_181200_1	290397.Adeh_0852	2.51e-12	79.0	COG0793@1|root,COG3485@1|root,COG0793@2|Bacteria,COG3485@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
SRR25158348_k127_185446_1	457570.Nther_2211	1.989e-33	148.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158348_k127_185446_2	696281.Desru_0531	8.005e-33	135.0	COG2068@1|root,COG2068@2|Bacteria,1UY6E@1239|Firmicutes,249PV@186801|Clostridia,260Y2@186807|Peptococcaceae	186801|Clostridia	S	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,NTP_transf_3
SRR25158348_k127_185446_3	243277.VC_A1019	2.989e-21	100.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,1XX1H@135623|Vibrionales	135623|Vibrionales	S	TQO small subunit DoxD	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158348_k127_185446_0	479434.Sthe_0863	6.278e-113	375.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,27Z0R@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158348_k127_188054_2	525257.HMPREF0204_11108	0.0008134	46.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,3ZSAC@59732|Chryseobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
SRR25158348_k127_188054_1	1031711.RSPO_c02747	1.177e-31	135.0	28KDQ@1|root,2ZAX1@2|Bacteria,1QY70@1224|Proteobacteria,2WHCH@28216|Betaproteobacteria,1KGBB@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_188054_0	497964.CfE428DRAFT_6370	3.743e-74	258.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158348_k127_192815_1	1090319.KE386571_gene2976	8.546e-70	259.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria,2K41C@204457|Sphingomonadales	204457|Sphingomonadales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_192815_0	83332.Rv1916	1.414e-106	351.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158348_k127_19926_2	289377.HL41_00765	1.937e-12	69.0	COG0333@1|root,COG0333@2|Bacteria,2GI2S@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158348_k127_19926_0	768710.DesyoDRAFT_4481	3.495e-83	288.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158348_k127_19926_1	268407.PWYN_19845	4.202e-42	173.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158348_k127_202599_0	671143.DAMO_1541	1.085e-153	494.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
SRR25158348_k127_202599_1	706587.Desti_4173	8.207e-127	421.0	COG1215@1|root,COG1215@2|Bacteria,1QVA1@1224|Proteobacteria,43BP8@68525|delta/epsilon subdivisions,2X70I@28221|Deltaproteobacteria,2MSKJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR25158348_k127_202599_2	439235.Dalk_4107	1.416e-40	165.0	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,42SQA@68525|delta/epsilon subdivisions,2WP3P@28221|Deltaproteobacteria,2MM4B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158348_k127_202599_3	1144319.PMI16_01556	0.0001529	54.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,478EZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158348_k127_207666_12	521045.Kole_2089	2.014e-44	169.0	COG0441@1|root,COG0441@2|Bacteria,2GBXU@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158348_k127_207666_14	620914.JH621248_gene3214	1.317e-16	85.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1I44S@117743|Flavobacteriia,2YK14@290174|Aquimarina	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_207666_0	246194.CHY_2204	1.016e-202	648.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,42EM9@68295|Thermoanaerobacterales	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158348_k127_207666_10	1125863.JAFN01000001_gene341	1.731e-47	196.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR25158348_k127_207666_6	1169161.KB897713_gene6868	3.322e-82	299.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,WD40
SRR25158348_k127_207666_8	194439.CT0562	4.931e-64	225.0	COG1945@1|root,COG1945@2|Bacteria,1FDKS@1090|Chlorobi	1090|Chlorobi	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
SRR25158348_k127_207666_4	1280953.HOC_12423	3.32e-89	318.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,43X90@69657|Hyphomonadaceae	28211|Alphaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158348_k127_207666_2	204669.Acid345_4350	1.304e-134	442.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria,2JHPY@204432|Acidobacteriia	204432|Acidobacteriia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158348_k127_207666_7	748727.CLJU_c14410	2.93e-67	254.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,36DRS@31979|Clostridiaceae	186801|Clostridia	M	Peptidase, S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158348_k127_207666_3	234267.Acid_0353	2.512e-127	416.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158348_k127_207666_5	671143.DAMO_0748	1.051e-82	286.0	COG1071@1|root,COG1071@2|Bacteria,2NPBB@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158348_k127_207666_9	1157490.EL26_15670	1.324e-63	230.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,4HH4H@91061|Bacilli,279KG@186823|Alicyclobacillaceae	91061|Bacilli	H	Biotin/lipoate A/B protein ligase family	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158348_k127_207666_16	1108045.GORHZ_126_00030	1.216e-10	69.0	2EGD2@1|root,33A4V@2|Bacteria,2GWY9@201174|Actinobacteria,4GECV@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158348_k127_207666_15	518637.EUBIFOR_01113	4.262e-11	71.0	COG4640@1|root,COG4640@2|Bacteria,1VB94@1239|Firmicutes,3VR6A@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,DUF4339,zinc_ribbon_2
SRR25158348_k127_207666_1	215803.DB30_6173	5.266e-153	496.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158348_k127_207666_11	314232.SKA53_01111	1.166e-44	171.0	2EZCI@1|root,33T6F@2|Bacteria,1R3D2@1224|Proteobacteria,2U00U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_207666_13	225937.HP15_1441	1.663e-17	83.0	2C01Y@1|root,32R67@2|Bacteria,1NWP4@1224|Proteobacteria,1STGD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_214867_1	123214.PERMA_A0042	1.567e-15	84.0	COG2433@1|root,COG2433@2|Bacteria,2G50E@200783|Aquificae	200783|Aquificae	S	Bacterial conjugation TrbI-like protein	-	-	-	ko:K12065	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TrbI
SRR25158348_k127_214867_0	631362.Thi970DRAFT_00149	7.729e-23	114.0	COG3451@1|root,COG3451@2|Bacteria,1MUEN@1224|Proteobacteria,1RMMX@1236|Gammaproteobacteria,1WXA7@135613|Chromatiales	135613|Chromatiales	U	TIGRFAM type-IV secretion system protein TraC	-	-	-	ko:K12063	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AAA_10,TraC_F_IV
SRR25158348_k127_216158_0	404380.Gbem_3265	2.342e-51	195.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42PDM@68525|delta/epsilon subdivisions,2WMKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158348_k127_216158_1	748658.KB907318_gene1043	5.23e-45	173.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
SRR25158348_k127_217350_1	1038867.AXAY01000014_gene5209	6.96e-99	329.0	COG0021@1|root,COG0176@1|root,COG0021@2|Bacteria,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,2TZC4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
SRR25158348_k127_217350_0	247490.KSU1_B0397	2.838e-192	627.0	COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes	203682|Planctomycetes	L	COG0553 Superfamily II DNA RNA	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
SRR25158348_k127_218393_1	1185876.BN8_02773	2.741e-80	273.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JRM@768503|Cytophagia	976|Bacteroidetes	T	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,PAS_3,PAS_9,Response_reg,Sigma54_activat
SRR25158348_k127_218393_2	1123276.KB893253_gene3423	9.289e-72	259.0	2EYC6@1|root,33RKI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_218393_0	935567.JAES01000001_gene2097	1.936e-83	291.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158348_k127_22632_0	247490.KSU1_C1266	2.412e-27	128.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158348_k127_22632_1	1319815.HMPREF0202_02329	6.037e-18	94.0	COG1762@1|root,COG1762@2|Bacteria,379WR@32066|Fusobacteria	32066|Fusobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
SRR25158348_k127_229204_0	1242864.D187_004585	1.386e-85	303.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42RWK@68525|delta/epsilon subdivisions,2WNCS@28221|Deltaproteobacteria,2YWYI@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SRR25158348_k127_230088_0	237368.SCABRO_01697	2.461e-141	460.0	COG0766@1|root,COG0766@2|Bacteria,2IWRI@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158348_k127_230088_4	379066.GAU_3929	8.876e-08	63.0	COG1655@1|root,COG1655@2|Bacteria,1ZSTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
SRR25158348_k127_230088_2	484770.UFO1_4287	2.912e-51	200.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4H2VA@909932|Negativicutes	909932|Negativicutes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158348_k127_230088_1	1120973.AQXL01000132_gene2220	9.218e-105	351.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,27865@186823|Alicyclobacillaceae	91061|Bacilli	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158348_k127_230088_3	1249627.D779_0843	4.554e-23	109.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158348_k127_230264_0	290397.Adeh_1207	3.839e-71	246.0	COG1028@1|root,COG1028@2|Bacteria,1MW4W@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158348_k127_231918_1	247490.KSU1_B0265	1.243e-16	89.0	COG2010@1|root,COG2010@2|Bacteria,2IZN4@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,EB_dh
SRR25158348_k127_231918_0	479434.Sthe_2667	1.258e-34	145.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158348_k127_236518_8	589865.DaAHT2_1767	7.709e-58	215.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,42VRI@68525|delta/epsilon subdivisions,2WRUV@28221|Deltaproteobacteria,2MPAI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158348_k127_236518_6	589865.DaAHT2_1766	6.71e-76	265.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,42TSF@68525|delta/epsilon subdivisions,2X5F6@28221|Deltaproteobacteria,2MM40@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158348_k127_236518_7	1173024.KI912151_gene2172	9.382e-66	240.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158348_k127_236518_2	1026882.MAMP_00819	3.284e-144	465.0	COG1216@1|root,COG1216@2|Bacteria,1R13P@1224|Proteobacteria,1T589@1236|Gammaproteobacteria,461V4@72273|Thiotrichales	72273|Thiotrichales	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158348_k127_236518_4	926550.CLDAP_06140	7.427e-128	416.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158348_k127_236518_0	1245469.S58_28580	7.36e-257	808.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3K2T1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158348_k127_236518_3	118168.MC7420_5089	4.272e-140	458.0	COG0438@1|root,COG0438@2|Bacteria,1G1ED@1117|Cyanobacteria,1H79T@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_236518_5	756067.MicvaDRAFT_2194	5.669e-118	407.0	COG1215@1|root,COG1215@2|Bacteria,1GQPQ@1117|Cyanobacteria,1H9XR@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158348_k127_236518_1	1144275.COCOR_08044	2.197e-149	483.0	COG0438@1|root,COG0438@2|Bacteria,1P8MT@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158348_k127_237551_0	530564.Psta_0378	5.405e-73	262.0	COG0072@1|root,COG0072@2|Bacteria,2IX0Q@203682|Planctomycetes	203682|Planctomycetes	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158348_k127_237551_1	1201293.AKXQ01000011_gene3422	4.438e-08	62.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158348_k127_238507_1	313612.L8106_09721	8.703e-29	117.0	COG0105@1|root,COG0105@2|Bacteria,1G4ZN@1117|Cyanobacteria,1HAIY@1150|Oscillatoriales	1117|Cyanobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158348_k127_238507_2	504472.Slin_5713	5.262e-14	82.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	GRASP55_65,PD40,PDZ_2,Peptidase_S41,Tricorn_C1
SRR25158348_k127_238507_0	237368.SCABRO_03338	6.57e-64	235.0	COG1196@1|root,COG1196@2|Bacteria,2IY32@203682|Planctomycetes	203682|Planctomycetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158348_k127_239851_1	161156.JQKW01000012_gene27	7.83e-21	93.0	COG1220@1|root,COG1220@2|Bacteria,2GGX7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158348_k127_239851_0	65393.PCC7424_0112	1.763e-25	124.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3KH8A@43988|Cyanothece	1117|Cyanobacteria	L	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158348_k127_239851_3	316279.Syncc9902_0386	1.357e-12	68.0	COG1225@1|root,COG1225@2|Bacteria,1G6AA@1117|Cyanobacteria,1H09N@1129|Synechococcus	1117|Cyanobacteria	O	Bacterioferritin comigratory	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158348_k127_239851_2	398512.JQKC01000032_gene4461	1.188e-18	88.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158348_k127_24312_1	1123508.JH636449_gene7300	3.253e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,2IZ91@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_24312_0	1379698.RBG1_1C00001G0798	5.793e-146	491.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
SRR25158348_k127_248174_0	518766.Rmar_1858	5.12e-139	448.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158348_k127_248174_1	926549.KI421517_gene1746	4.246e-37	160.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
SRR25158348_k127_250632_0	1123371.ATXH01000013_gene1532	4.56e-110	370.0	COG1109@1|root,COG1109@2|Bacteria,2GGQT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158348_k127_250632_2	756499.Desde_0695	1.166e-50	191.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,2611Q@186807|Peptococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158348_k127_250632_1	404589.Anae109_2337	4.604e-77	270.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158348_k127_252941_0	525897.Dbac_1184	2.43e-116	388.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2MBD3@213115|Desulfovibrionales	28221|Deltaproteobacteria	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158348_k127_252941_1	404589.Anae109_4070	5.087e-36	145.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria	1224|Proteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	iEcolC_1368.EcolC_1983	Sod_Cu
SRR25158348_k127_252941_2	1396141.BATP01000056_gene3118	1.455e-18	94.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158348_k127_255351_5	886293.Sinac_1734	9.243e-05	46.0	2EK1E@1|root,33DRX@2|Bacteria,2J1JB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-RING_1
SRR25158348_k127_255351_2	886293.Sinac_1734	1.343e-13	81.0	2EK1E@1|root,33DRX@2|Bacteria,2J1JB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-RING_1
SRR25158348_k127_255351_4	886293.Sinac_1734	1.609e-09	68.0	2EK1E@1|root,33DRX@2|Bacteria,2J1JB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-RING_1
SRR25158348_k127_255351_1	195105.CN97_12195	1.858e-17	94.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158348_k127_262199_0	575540.Isop_1260	2.702e-87	302.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	2|Bacteria	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_262199_1	1121020.JIAG01000001_gene1061	2.642e-62	231.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,1W8Q4@1268|Micrococcaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_262199_2	1121020.JIAG01000001_gene1061	7.932e-48	191.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,1W8Q4@1268|Micrococcaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_263856_0	247490.KSU1_B0370	3.014e-285	895.0	COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158348_k127_263856_1	469383.Cwoe_3922	1.753e-06	60.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CR9B@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_264184_3	1157490.EL26_00515	1.91e-72	263.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,277VB@186823|Alicyclobacillaceae	91061|Bacilli	S	Transporter associated domain	corC1	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158348_k127_264184_6	565034.BHWA1_01009	1.225e-18	100.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2J6PF@203691|Spirochaetes	203691|Spirochaetes	GT	Pts system, fructose-specific	fruA-2	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158348_k127_264184_2	1380394.JADL01000004_gene6065	9.335e-78	267.0	COG2227@1|root,COG2227@2|Bacteria,1QXTA@1224|Proteobacteria	1224|Proteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158348_k127_264184_5	1379698.RBG1_1C00001G0675	6.576e-65	235.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158348_k127_264184_0	941449.dsx2_3382	1.153e-173	573.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158348_k127_264184_4	300852.55772952	8.724e-72	256.0	COG1899@1|root,COG1899@2|Bacteria,1WI9Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158348_k127_264184_1	671143.DAMO_2943	5.003e-104	347.0	COG0451@1|root,COG0451@2|Bacteria,2NPSM@2323|unclassified Bacteria	2|Bacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO0058,iYL1228.KPN_03963	Epimerase
SRR25158348_k127_264184_7	1191523.MROS_1419	8.682e-09	65.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158348_k127_265306_2	311424.DhcVS_1471	2.14e-41	162.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,34D0W@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158348_k127_265306_3	448385.sce4366	7.342e-27	112.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2YVXY@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158348_k127_265306_1	1173028.ANKO01000250_gene2299	5.927e-86	296.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158348_k127_265306_0	1380394.JADL01000024_gene101	0.0	1046.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
SRR25158348_k127_265306_4	1210884.HG799465_gene11812	1.653e-12	80.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	PD40,Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_265608_2	279238.Saro_0152	7.494e-59	220.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria,2K1ZA@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158348_k127_265608_4	765910.MARPU_13595	9.765e-27	117.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1WZI2@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_265608_0	479434.Sthe_1305	5.427e-203	647.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi,27Y4D@189775|Thermomicrobia	189775|Thermomicrobia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158348_k127_265608_3	156889.Mmc1_3712	1.343e-55	221.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158348_k127_265608_1	290397.Adeh_0670	4.285e-130	422.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158348_k127_267857_6	635013.TherJR_1522	5.385e-29	120.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,260HV@186807|Peptococcaceae	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
SRR25158348_k127_267857_5	886293.Sinac_7410	1.922e-53	207.0	COG1419@1|root,COG1419@2|Bacteria,2IYTZ@203682|Planctomycetes	203682|Planctomycetes	N	GTP-binding signal recognition particle SRP54	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
SRR25158348_k127_267857_4	1303518.CCALI_00993	4.171e-61	235.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	flhG	-	-	ko:K02282,ko:K04562	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
SRR25158348_k127_267857_2	756272.Plabr_1412	3.105e-66	235.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158348_k127_267857_3	429009.Adeg_0596	3.183e-63	226.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,42G1B@68295|Thermoanaerobacterales	186801|Clostridia	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158348_k127_267857_1	864073.HFRIS_005478	3.615e-84	304.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,472WQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158348_k127_267857_0	653733.Selin_0490	1.971e-148	486.0	COG0161@1|root,COG0161@2|Bacteria	2|Bacteria	H	adenosylmethionine-8-amino-7-oxononanoate transaminase activity	bioA	-	2.6.1.105,2.6.1.62	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231,R10699	RC00006,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS12705	Aminotran_3
SRR25158348_k127_268708_0	1121897.AUGO01000007_gene505	3.464e-39	156.0	COG0463@1|root,COG0463@2|Bacteria,4PKUK@976|Bacteroidetes,1IJFN@117743|Flavobacteriia,2P0Q6@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158348_k127_268708_1	1121428.DESHY_110517___1	7.044e-30	135.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,261SN@186807|Peptococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158348_k127_268708_2	661478.OP10G_1678	2.315e-17	82.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158348_k127_269286_0	1210884.HG799476_gene15337	1.444e-71	249.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158348_k127_269286_1	329726.AM1_1355	6.177e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,1G8SN@1117|Cyanobacteria	1117|Cyanobacteria	U	Type IV pilin-like G and H, putative	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_GH
SRR25158348_k127_270677_0	575540.Isop_2819	8.667e-182	589.0	COG2804@1|root,COG2804@2|Bacteria,2IXSA@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158348_k127_270677_1	575540.Isop_2820	2.267e-134	436.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	203682|Planctomycetes	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158348_k127_270677_3	679200.HMPREF9333_00113	6.489e-08	65.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158348_k127_270677_2	247490.KSU1_B0641	2.167e-20	101.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
SRR25158348_k127_272577_3	247490.KSU1_C1552	3.034e-05	49.0	2BWMY@1|root,331GB@2|Bacteria,2J0M4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_272577_0	671143.DAMO_2856	7.676e-317	1007.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
SRR25158348_k127_272577_1	1242864.D187_007879	8.711e-67	239.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YUPQ@29|Myxococcales	28221|Deltaproteobacteria	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRR25158348_k127_272577_2	1235813.JCM10003_1823	1.501e-15	81.0	COG3404@1|root,COG3404@2|Bacteria,4NN2J@976|Bacteroidetes,2FPSN@200643|Bacteroidia,4AMB8@815|Bacteroidaceae	976|Bacteroidetes	E	COG3404 Methenyl tetrahydrofolate cyclohydrolase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C,Peptidase_M78
SRR25158348_k127_272707_0	479432.Sros_2437	6.179e-67	243.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4EGXY@85012|Streptosporangiales	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158348_k127_272707_1	290397.Adeh_2794	1.404e-42	168.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2YVWN@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158348_k127_272707_6	1172181.KB911705_gene5182	4.401e-05	55.0	2F8BU@1|root,31VB2@2|Bacteria,2GVB8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_272707_2	1173028.ANKO01000227_gene1228	1.721e-41	165.0	COG0330@1|root,COG0330@2|Bacteria,1G37J@1117|Cyanobacteria,1H9TF@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158348_k127_272707_3	1215915.BN193_03395	1.14e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1YB4E@1357|Lactococcus	91061|Bacilli	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_272707_4	879308.HMPREF9130_0459	3.941e-15	78.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,22GGC@1570339|Peptoniphilaceae	186801|Clostridia	T	Response regulator receiver domain protein	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_27397_0	340099.Teth39_0215	2.804e-124	421.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,42FCI@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158348_k127_27397_1	1123508.JH636439_gene1349	2.553e-08	66.0	COG2982@1|root,COG2982@2|Bacteria,2IYVI@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
SRR25158348_k127_27397_2	543728.Vapar_4648	0.0002224	46.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria,4AFBS@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158348_k127_277224_1	582402.Hbal_1954	0.0002947	52.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,43WVT@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG1520 FOG WD40-like repeat	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
SRR25158348_k127_277224_0	1123242.JH636434_gene3773	1.28e-60	219.0	COG4102@1|root,COG4102@2|Bacteria,2IYAK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158348_k127_280128_1	1173023.KE650771_gene4375	7.929e-42	174.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G5G9@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
SRR25158348_k127_280128_0	309801.trd_A0628	1.04e-289	904.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158348_k127_280502_0	1047013.AQSP01000109_gene2431	1.193e-31	141.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_280838_0	1521187.JPIM01000050_gene3431	5.488e-138	456.0	COG3975@1|root,COG3975@2|Bacteria,2GAB7@200795|Chloroflexi,374W2@32061|Chloroflexia	32061|Chloroflexia	S	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158348_k127_281875_2	1123319.AUBE01000027_gene4771	2.783e-16	93.0	COG0840@1|root,2Z8BY@2|Bacteria,2IGSE@201174|Actinobacteria	201174|Actinobacteria	NT	Methyl-accepting Chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_281875_1	643562.Daes_2956	4.982e-23	114.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2M7Z5@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,SpoIIE,dCache_1,dCache_2
SRR25158348_k127_281875_0	161156.JQKW01000013_gene149	9.732e-32	142.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158348_k127_281875_3	1192034.CAP_7069	6.964e-08	54.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2YY7F@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter, ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158348_k127_286313_2	909663.KI867150_gene1025	3.522e-37	144.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RJU@68525|delta/epsilon subdivisions,2WNBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158348_k127_286313_1	316055.RPE_1774	4.71e-52	199.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,2U283@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
SRR25158348_k127_286313_0	1121104.AQXH01000001_gene1268	8.21e-109	381.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158348_k127_28703_8	298655.KI912267_gene6838	0.0004444	48.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
SRR25158348_k127_28703_6	215803.DB30_1496	1.176e-13	78.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1NIID@1224|Proteobacteria,42YIQ@68525|delta/epsilon subdivisions,2WUCK@28221|Deltaproteobacteria,2YTXX@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_28703_4	640511.BC1002_1278	3.719e-22	112.0	COG1262@1|root,COG2319@1|root,COG1262@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
SRR25158348_k127_28703_7	1944.JOAZ01000025_gene2797	2.14e-06	61.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria,4194U@629295|Streptomyces griseus group	201174|Actinobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_28703_3	368407.Memar_0653	5.047e-48	182.0	COG0122@1|root,arCOG00464@2157|Archaea,2XU5Y@28890|Euryarchaeota,2N9M2@224756|Methanomicrobia	224756|Methanomicrobia	L	8-oxoguanine DNA glycosylase domain protein	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
SRR25158348_k127_28703_2	247490.KSU1_C1120	6.646e-58	213.0	COG0289@1|root,COG0289@2|Bacteria,2IX9G@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158348_k127_28703_5	595460.RRSWK_04362	3.86e-19	92.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158348_k127_28703_0	1089551.KE386572_gene2424	3.217e-134	439.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,4BPP4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158348_k127_28703_1	1232410.KI421426_gene1410	2.126e-106	350.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
SRR25158348_k127_290029_1	1166130.H650_02080	1.293e-07	63.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,3X0J9@547|Enterobacter	1236|Gammaproteobacteria	E	extracellular solute-binding protein, family 5	mppA	GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iUMNK88_1353.UMNK88_1667	SBP_bac_5
SRR25158348_k127_290029_0	1268237.G114_11455	2.304e-32	131.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158348_k127_291149_0	530564.Psta_3482	5.921e-72	268.0	COG5492@1|root,COG5492@2|Bacteria,2J1RI@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
SRR25158348_k127_294840_0	247490.KSU1_D0830	4.726e-295	925.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
SRR25158348_k127_294840_1	247490.KSU1_D0832	4.57e-116	382.0	COG0825@1|root,COG0825@2|Bacteria,2IX7N@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158348_k127_294840_2	443143.GM18_0614	2.42e-10	71.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Cu_amine_oxidN1,PD40
SRR25158348_k127_29492_2	234267.Acid_0825	3.152e-24	116.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_29492_1	671143.DAMO_1981	1.367e-52	211.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158348_k127_29492_0	880073.Calab_1817	1.282e-77	282.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158348_k127_29611_0	997346.HMPREF9374_3672	3.343e-194	633.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,27CI0@186824|Thermoactinomycetaceae	91061|Bacilli	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
SRR25158348_k127_29611_5	1123508.JH636449_gene7371	1.682e-08	66.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
SRR25158348_k127_29611_1	1123508.JH636449_gene7371	4.678e-141	460.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
SRR25158348_k127_29611_4	118163.Ple7327_2327	2.179e-35	143.0	COG0457@1|root,COG0457@2|Bacteria	118163.Ple7327_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_29611_2	1379698.RBG1_1C00001G0806	4.836e-106	354.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158348_k127_29611_3	1379698.RBG1_1C00001G0805	8.86e-105	358.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158348_k127_296888_3	1191523.MROS_1859	2.064e-09	64.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2,SpoIIE
SRR25158348_k127_296888_1	1279009.ADICEAN_03267	4.297e-149	482.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158348_k127_296888_0	234267.Acid_2300	6.436e-207	702.0	COG2373@1|root,COG2373@2|Bacteria,3Y439@57723|Acidobacteria	57723|Acidobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
SRR25158348_k127_296888_5	1123366.TH3_18028	0.000119	49.0	COG4430@1|root,COG4430@2|Bacteria,1RJGC@1224|Proteobacteria,2U3AS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
SRR25158348_k127_296888_4	589865.DaAHT2_0591	2.139e-05	53.0	2DR9X@1|root,33AUW@2|Bacteria,1NKHC@1224|Proteobacteria	1224|Proteobacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
SRR25158348_k127_296888_2	358681.BBR47_03560	2.232e-22	109.0	28XGS@1|root,2ZJE7@2|Bacteria,1V1QY@1239|Firmicutes,4HGQC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_302991_4	1236976.JCM16418_1438	0.0007129	51.0	COG3325@1|root,COG3397@1|root,COG3325@2|Bacteria,COG3397@2|Bacteria,1TT45@1239|Firmicutes,4HEJN@91061|Bacilli,26TIE@186822|Paenibacillaceae	91061|Bacilli	G	PFAM chitin-binding domain 3 protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_5_12,LPMO_10,fn3
SRR25158348_k127_302991_1	290397.Adeh_0919	1.568e-34	152.0	2ANJD@1|root,31DIF@2|Bacteria,1QAU4@1224|Proteobacteria,43E3V@68525|delta/epsilon subdivisions,2WZMZ@28221|Deltaproteobacteria,2Z0Q6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_302991_3	1379698.RBG1_1C00001G0853	4.053e-06	57.0	290MS@1|root,2ZNA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_302991_0	1125863.JAFN01000001_gene2452	4.967e-37	145.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42W8P@68525|delta/epsilon subdivisions,2WRV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158348_k127_302991_5	338963.Pcar_2061	0.0008612	50.0	COG2340@1|root,COG2340@2|Bacteria,1NJB9@1224|Proteobacteria,42Y4H@68525|delta/epsilon subdivisions,2WSKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_302991_2	1123508.JH636442_gene4228	1.721e-16	81.0	COG0319@1|root,COG0319@2|Bacteria,2J0MV@203682|Planctomycetes	203682|Planctomycetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158348_k127_30587_5	555088.DealDRAFT_0340	3.744e-05	48.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42JYU@68298|Syntrophomonadaceae	186801|Clostridia	H	anthranilate synthase, component	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13503,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
SRR25158348_k127_30587_0	1089548.KI783301_gene190	3.93e-203	645.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,3WFDZ@539002|Bacillales incertae sedis	91061|Bacilli	C	Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158348_k127_30587_2	435590.BVU_0327	1.385e-22	103.0	2DMPS@1|root,32SXU@2|Bacteria,4NTIT@976|Bacteroidetes,2G0J8@200643|Bacteroidia,4AR0W@815|Bacteroidaceae	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_30587_1	344747.PM8797T_30347	3.169e-52	192.0	COG0283@1|root,COG0283@2|Bacteria,2IZ6S@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158348_k127_30587_4	765952.PUV_08220	3.549e-07	64.0	COG2911@1|root,COG2911@2|Bacteria,2JG5X@204428|Chlamydiae	204428|Chlamydiae	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158348_k127_30587_3	1123371.ATXH01000007_gene561	2.006e-11	74.0	COG4775@1|root,COG4775@2|Bacteria,2GGVC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158348_k127_306647_0	290397.Adeh_2221	1.035e-253	792.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,42YX3@68525|delta/epsilon subdivisions,2WTY2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158348_k127_306647_1	1123278.KB893574_gene6163	1.578e-240	756.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158348_k127_307469_0	330214.NIDE0029	1.015e-127	427.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009	ko02020,ko02025,ko05132,map02020,map02025,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat
SRR25158348_k127_307469_1	1235835.C814_01856	4.348e-50	196.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158348_k127_307469_2	1303518.CCALI_01386	2.388e-48	177.0	COG0489@1|root,COG0489@2|Bacteria	2|Bacteria	D	protein tyrosine kinase activity	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158348_k127_314077_4	436229.JOEH01000016_gene7153	2.561e-13	82.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,2NGPP@228398|Streptacidiphilus	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158348_k127_314077_5	313596.RB2501_02980	7.689e-11	69.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_314077_2	246197.MXAN_2189	1.101e-42	164.0	COG3795@1|root,COG3795@2|Bacteria,1RKYW@1224|Proteobacteria,43DU4@68525|delta/epsilon subdivisions,2WYVK@28221|Deltaproteobacteria,2Z0QY@29|Myxococcales	28221|Deltaproteobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158348_k127_314077_0	290397.Adeh_3125	1.242e-80	278.0	COG0596@1|root,COG0596@2|Bacteria,1RIUT@1224|Proteobacteria,434KF@68525|delta/epsilon subdivisions,2WYXT@28221|Deltaproteobacteria,2Z0VT@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158348_k127_314077_1	448385.sce1490	8.563e-53	196.0	COG3795@1|root,COG3795@2|Bacteria,1Q42B@1224|Proteobacteria,439VS@68525|delta/epsilon subdivisions,2X59V@28221|Deltaproteobacteria,2Z0B4@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158348_k127_314077_3	1121920.AUAU01000012_gene2703	3.139e-21	93.0	COG2102@1|root,COG2102@2|Bacteria,3Y46Z@57723|Acidobacteria	57723|Acidobacteria	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
SRR25158348_k127_32322_2	595460.RRSWK_05351	1.247e-12	70.0	COG1449@1|root,COG1449@2|Bacteria,2IY67@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158348_k127_32322_3	290397.Adeh_1075	3.056e-05	54.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
SRR25158348_k127_32322_0	370438.PTH_2228	8.575e-187	597.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SRR25158348_k127_32322_1	378806.STAUR_8131	2.411e-77	273.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WM87@28221|Deltaproteobacteria,2YUDN@29|Myxococcales	28221|Deltaproteobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
SRR25158348_k127_323657_6	926549.KI421517_gene3224	0.0003338	46.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158348_k127_323657_1	497964.CfE428DRAFT_4863	2.575e-96	337.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_323657_2	472759.Nhal_1439	2.177e-85	301.0	COG3284@1|root,COG4251@1|root,COG3284@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
SRR25158348_k127_323657_5	215803.DB30_1801	1.61e-08	61.0	28UXW@1|root,2ZH1P@2|Bacteria,1Q3E7@1224|Proteobacteria,43403@68525|delta/epsilon subdivisions,2X4CD@28221|Deltaproteobacteria,2YYR8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_323657_3	665571.STHERM_c03630	2.158e-64	232.0	COG0432@1|root,COG0432@2|Bacteria,2J7PN@203691|Spirochaetes	203691|Spirochaetes	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158348_k127_323657_0	518766.Rmar_2384	9.629e-133	442.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158348_k127_323657_4	485913.Krac_3704	5.79e-19	95.0	COG0477@1|root,COG2814@2|Bacteria,2G77Q@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158348_k127_326635_1	247490.KSU1_D0660	1.162e-49	183.0	COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158348_k127_326635_0	886293.Sinac_6616	5.644e-107	363.0	COG0113@1|root,COG0113@2|Bacteria,2IWU8@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158348_k127_326635_2	671143.DAMO_1081	8.251e-22	103.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2NPBQ@2323|unclassified Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobA	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K01719,ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,TP_methylase
SRR25158348_k127_328867_0	247490.KSU1_B0016	2.52e-137	444.0	COG0158@1|root,COG0158@2|Bacteria,2IWT3@203682|Planctomycetes	203682|Planctomycetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
SRR25158348_k127_328867_1	161156.JQKW01000003_gene889	2.48e-31	127.0	COG0191@1|root,COG0191@2|Bacteria,2GHBA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158348_k127_33221_1	1403819.BATR01000124_gene4408	2.361e-32	129.0	29IJ4@1|root,305GB@2|Bacteria,46VRX@74201|Verrucomicrobia,2IVQS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR25158348_k127_33221_2	1385511.N783_21130	1.132e-11	77.0	COG3832@1|root,COG3832@2|Bacteria,1VDCF@1239|Firmicutes,4HM0C@91061|Bacilli,2YAMX@289201|Pontibacillus	91061|Bacilli	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158348_k127_33221_0	1396141.BATP01000003_gene5168	7.851e-67	237.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_334551_0	479434.Sthe_3028	1.992e-118	400.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158348_k127_334551_1	886293.Sinac_7050	7.871e-17	94.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IY73@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16
SRR25158348_k127_334607_1	1552123.EP57_05630	5.992e-06	53.0	2AEMC@1|root,314H9@2|Bacteria,1W0UA@1239|Firmicutes,4HRRY@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158348_k127_334607_0	247490.KSU1_C1000	6.573e-162	527.0	COG1198@1|root,COG1198@2|Bacteria,2IY1F@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158348_k127_334645_0	1123376.AUIU01000014_gene642	2.763e-131	433.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158348_k127_334645_5	331678.Cphamn1_1600	4.626e-24	115.0	COG0713@1|root,COG0713@2|Bacteria,1FE6D@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158348_k127_334645_6	1123277.KB893181_gene2215	5.965e-13	79.0	COG0839@1|root,COG0839@2|Bacteria,4NNMC@976|Bacteroidetes,47PS1@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158348_k127_334645_1	880073.Calab_2689	3.218e-104	352.0	COG1005@1|root,COG1005@2|Bacteria,2NQIK@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158348_k127_334645_2	880073.Calab_2691	2.356e-40	154.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158348_k127_334645_3	290512.Paes_0842	7.366e-39	150.0	COG0838@1|root,COG0838@2|Bacteria,1FDY8@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158348_k127_334645_7	1172190.M947_11530	0.0003687	52.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2YNZU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158348_k127_334645_4	883069.HMPREF9238_00544	6.85e-29	121.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4D431@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_338054_1	575540.Isop_2743	2.596e-34	149.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158348_k127_338054_0	886293.Sinac_2616	4.202e-127	415.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158348_k127_339799_0	1232410.KI421421_gene3403	3.039e-114	377.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,43S2S@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158348_k127_339799_2	671143.DAMO_1104	5.296e-46	184.0	COG3746@1|root,COG3746@2|Bacteria,2NRQ1@2323|unclassified Bacteria	2|Bacteria	P	phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
SRR25158348_k127_339799_4	498761.HM1_2853	8.099e-31	137.0	COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,24G1Y@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigZ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_339799_1	1267535.KB906767_gene5005	5.898e-112	374.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158348_k127_339799_5	498848.TaqDRAFT_4424	3.777e-28	120.0	COG0517@1|root,COG0517@2|Bacteria,1WI6I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158348_k127_339799_3	926550.CLDAP_21370	7.047e-39	156.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi	200795|Chloroflexi	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158348_k127_341175_1	247490.KSU1_D0386	1.368e-82	280.0	COG0192@1|root,COG0192@2|Bacteria,2IXCJ@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158348_k127_341175_0	247490.KSU1_D0387	1.657e-184	597.0	COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes	203682|Planctomycetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158348_k127_341175_2	215803.DB30_0583	3.537e-30	122.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,42P3H@68525|delta/epsilon subdivisions,2WK0J@28221|Deltaproteobacteria,2YZJT@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_341296_0	661478.OP10G_4147	8.554e-53	211.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158348_k127_341296_1	945713.IALB_0345	2.516e-14	80.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158348_k127_341296_2	1449351.RISW2_16980	0.0005371	47.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria	1224|Proteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158348_k127_342140_1	290397.Adeh_0131	6.843e-113	381.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2WIY0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SRR25158348_k127_342140_2	521674.Plim_0306	2.906e-28	132.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
SRR25158348_k127_342140_0	247490.KSU1_C0313	1.824e-156	505.0	COG1066@1|root,COG1066@2|Bacteria,2IYD6@203682|Planctomycetes	203682|Planctomycetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
SRR25158348_k127_342140_3	1463820.JOGW01000007_gene1885	1.043e-06	57.0	2ECXK@1|root,336UT@2|Bacteria,2IKFV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_344843_4	357808.RoseRS_4350	6.32e-28	121.0	COG2045@1|root,COG2045@2|Bacteria,2G8Z5@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ComB family	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158348_k127_344843_3	1168034.FH5T_19715	4.869e-29	119.0	COG0724@1|root,COG0724@2|Bacteria,4NSXX@976|Bacteroidetes,2FUB9@200643|Bacteroidia	976|Bacteroidetes	S	COG COG0724 RNA-binding proteins (RRM domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158348_k127_344843_0	518766.Rmar_1923	5.422e-104	347.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRR25158348_k127_344843_1	95619.PM1_0205680	8.573e-77	270.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria	1224|Proteobacteria	E	D-Amino acid dehydrogenase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158348_k127_344843_2	1340493.JNIF01000003_gene4191	6.596e-45	169.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158348_k127_344948_1	644966.Tmar_2166	5.192e-64	231.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WCGC@538999|Clostridiales incertae sedis	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158348_k127_344948_2	1123368.AUIS01000006_gene567	1.611e-34	136.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1T3Z8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
SRR25158348_k127_344948_0	1278073.MYSTI_00693	6.008e-252	790.0	COG0784@1|root,COG0840@1|root,COG2199@1|root,COG2770@1|root,COG5002@1|root,COG0784@2|Bacteria,COG0840@2|Bacteria,COG2770@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2YU1H@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
SRR25158348_k127_359596_0	1283300.ATXB01000002_gene3027	5.793e-22	100.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XEQU@135618|Methylococcales	135618|Methylococcales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158348_k127_363315_1	1254432.SCE1572_14060	1.055e-23	105.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2Z1VX@29|Myxococcales	28221|Deltaproteobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158348_k127_363315_2	1500894.JQNN01000001_gene2020	2.082e-16	89.0	COG3153@1|root,COG3153@2|Bacteria,1NGVC@1224|Proteobacteria	1224|Proteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
SRR25158348_k127_363315_0	518766.Rmar_2308	1.531e-62	229.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1FJ13@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158348_k127_375899_0	671143.DAMO_1217	1.294e-157	513.0	COG0439@1|root,COG0439@2|Bacteria,2NNKD@2323|unclassified Bacteria	2|Bacteria	I	carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01965,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00373,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158348_k127_375899_1	448385.sce6407	9.265e-44	163.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
SRR25158348_k127_377169_3	497964.CfE428DRAFT_1107	8.676e-37	146.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_377169_0	479434.Sthe_1974	2.241e-134	452.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia	189775|Thermomicrobia	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158348_k127_377169_1	215803.DB30_5299	2.252e-103	369.0	2EF95@1|root,33921@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_377169_4	1437882.AZRU01000012_gene3467	1.934e-05	53.0	COG0454@1|root,COG0456@2|Bacteria,1N15I@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158348_k127_377169_2	234267.Acid_7473	6.539e-58	210.0	COG1028@1|root,COG1028@2|Bacteria,3Y4CZ@57723|Acidobacteria	57723|Acidobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158348_k127_389095_2	1379698.RBG1_1C00001G0979	5.487e-60	226.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158348_k127_389095_4	243231.GSU1900	6.457e-48	184.0	COG0767@1|root,COG0767@2|Bacteria,1RHNJ@1224|Proteobacteria,42SNW@68525|delta/epsilon subdivisions,2WPKT@28221|Deltaproteobacteria,43T2D@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158348_k127_389095_3	717605.Theco_2427	8.403e-52	190.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,26TNS@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158348_k127_389095_1	1179773.BN6_73080	3.762e-75	263.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DZZ0@85010|Pseudonocardiales	201174|Actinobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158348_k127_389095_0	760568.Desku_1207	1.497e-223	706.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158348_k127_389095_5	448385.sce1655	1.071e-35	136.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,2YV7A@29|Myxococcales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158348_k127_390690_0	671143.DAMO_3020	1.836e-34	137.0	COG1051@1|root,COG2138@1|root,COG1051@2|Bacteria,COG2138@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	cbiX	-	1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3	ko:K00077,ko:K01092,ko:K03574,ko:K03795	ko00521,ko00562,ko00770,ko00860,ko01100,ko01110,ko01120,ko04070,map00521,map00562,map00770,map00860,map01100,map01110,map01120,map04070	M00119,M00131	R01185,R01186,R01187,R02472,R05807	RC00078,RC00726,RC01012	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CbiX,NUDIX
SRR25158348_k127_390690_1	401526.TcarDRAFT_2376	1.353e-24	115.0	COG0697@1|root,COG0697@2|Bacteria,1V0DI@1239|Firmicutes,4H4CC@909932|Negativicutes	909932|Negativicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158348_k127_390690_2	1304284.L21TH_1014	3.951e-06	54.0	COG2227@1|root,COG2227@2|Bacteria,1V218@1239|Firmicutes,25EUC@186801|Clostridia,36UUN@31979|Clostridiaceae	186801|Clostridia	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158348_k127_395265_3	886293.Sinac_5245	1.734e-10	73.0	COG4886@1|root,COG4886@2|Bacteria,2J0HP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
SRR25158348_k127_395265_2	344747.PM8797T_21918	1.246e-42	175.0	28VDX@1|root,2ZBVF@2|Bacteria,2IWRK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1598
SRR25158348_k127_395265_0	247490.KSU1_D0796	1.472e-186	616.0	COG1154@1|root,COG1154@2|Bacteria,2IYHC@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158348_k127_395265_1	886293.Sinac_7456	3.056e-79	274.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158348_k127_399576_2	1200792.AKYF01000007_gene840	0.0001944	45.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158348_k127_399576_1	330214.NIDE3653	4.898e-09	63.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	NTF2,SnoaL_2
SRR25158348_k127_399576_0	1385510.N781_15195	2.107e-16	93.0	COG1196@1|root,COG1196@2|Bacteria,1UIE6@1239|Firmicutes,4IT31@91061|Bacilli,2YAFZ@289201|Pontibacillus	91061|Bacilli	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158348_k127_400628_2	1122221.JHVI01000004_gene147	1.758e-39	153.0	2CMS6@1|root,32SFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158348_k127_400628_1	867903.ThesuDRAFT_01659	2.386e-69	245.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WCHN@538999|Clostridiales incertae sedis	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158348_k127_400628_0	247490.KSU1_D0697	1.904e-81	282.0	COG1181@1|root,COG1181@2|Bacteria,2IZHT@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158348_k127_400628_4	1123242.JH636436_gene469	1.207e-07	61.0	COG1589@1|root,COG1589@2|Bacteria,2J0ZH@203682|Planctomycetes	203682|Planctomycetes	M	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_405319_2	1211579.PP4_26520	8.872e-36	154.0	COG0596@1|root,COG0596@2|Bacteria,1R584@1224|Proteobacteria,1RQHF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158348_k127_405319_0	1250005.PHEL85_1492	1.708e-86	294.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1HZKX@117743|Flavobacteriia	976|Bacteroidetes	S	phenazine biosynthesis protein, PhzF family	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158348_k127_405319_1	903818.KI912268_gene1212	6.529e-75	264.0	COG3858@1|root,COG3858@2|Bacteria,3Y46G@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase, family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158348_k127_405319_3	100226.SCO5053	4.242e-12	79.0	COG0726@1|root,COG0726@2|Bacteria,2GMZR@201174|Actinobacteria	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158348_k127_417010_0	7176.CPIJ013219-PA	1.005e-57	210.0	COG1028@1|root,KOG0725@2759|Eukaryota,38BUC@33154|Opisthokonta,3BC34@33208|Metazoa,3D09G@33213|Bilateria,41XDM@6656|Arthropoda,3SIYY@50557|Insecta,455PX@7147|Diptera,45BSS@7148|Nematocera	33208|Metazoa	Q	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158348_k127_417726_0	794903.OPIT5_02105	3.421e-42	175.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia,3K7VK@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_417726_1	502025.Hoch_6271	1.82e-20	98.0	2DY29@1|root,32V4J@2|Bacteria,1P2QH@1224|Proteobacteria,43F3S@68525|delta/epsilon subdivisions,2X9U6@28221|Deltaproteobacteria,2YV4T@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_418741_9	345219.Bcoa_1150	1.869e-35	139.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,1ZFMC@1386|Bacillus	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158348_k127_418741_4	1120972.AUMH01000017_gene732	1.851e-52	191.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,2793R@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158348_k127_418741_12	1122132.AQYH01000018_gene1085	2.139e-28	127.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria,4BEQD@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158348_k127_418741_5	1232430.CAVG010000149_gene1550	6.19e-50	183.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,4GXWC@90964|Staphylococcaceae	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158348_k127_418741_10	1123372.AUIT01000013_gene1720	1.673e-34	139.0	COG0200@1|root,COG0200@2|Bacteria,2GHVD@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158348_k127_418741_0	237368.SCABRO_03487	7.685e-113	379.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158348_k127_418741_2	1125863.JAFN01000001_gene3315	5.499e-69	240.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158348_k127_418741_1	1128111.HMPREF0870_01842	5.037e-69	265.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158348_k127_418741_11	237368.SCABRO_03484	1.849e-31	125.0	COG0361@1|root,COG0361@2|Bacteria,2J0T1@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158348_k127_418741_13	387092.NIS_0245	1.742e-11	70.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2YQQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158348_k127_418741_8	1382306.JNIM01000001_gene3524	6.14e-43	160.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158348_k127_418741_6	886293.Sinac_0462	2.303e-49	180.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158348_k127_418741_3	1121423.JONT01000027_gene633	3.367e-58	209.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,260U9@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158348_k127_418741_7	237368.SCABRO_03478	6.563e-47	175.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158348_k127_425214_5	237368.SCABRO_00695	0.0001912	48.0	COG1450@1|root,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158348_k127_425214_4	344747.PM8797T_08219	1.269e-12	78.0	COG1450@1|root,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158348_k127_425214_2	596330.HMPREF0628_0715	2.933e-22	106.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,22HD4@1570339|Peptoniphilaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158348_k127_425214_0	756272.Plabr_0383	3.623e-130	432.0	COG0322@1|root,COG0322@2|Bacteria,2IWVR@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
SRR25158348_k127_425214_3	448385.sce0142	3.146e-14	80.0	2BGYF@1|root,32AYH@2|Bacteria,1QAYP@1224|Proteobacteria,435CU@68525|delta/epsilon subdivisions,2WZQB@28221|Deltaproteobacteria,2Z2IB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_425214_1	1254432.SCE1572_00820	1.573e-27	114.0	COG3220@1|root,COG3220@2|Bacteria,1Q38G@1224|Proteobacteria,438ZE@68525|delta/epsilon subdivisions,2X44P@28221|Deltaproteobacteria,2YY8Z@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
SRR25158348_k127_425895_1	107636.JQNK01000009_gene2804	0.0002712	49.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,36ZUC@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
SRR25158348_k127_425895_0	1230342.CTM_09941	6.677e-86	307.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,24CHH@186801|Clostridia,36F1C@31979|Clostridiaceae	186801|Clostridia	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158348_k127_428407_4	760117.JN27_18400	2.713e-55	197.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,474QB@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158348_k127_428407_1	1121468.AUBR01000016_gene2303	4.471e-131	438.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158348_k127_428407_5	243090.RB10119	7.224e-53	207.0	COG0515@1|root,COG2358@1|root,COG0515@2|Bacteria,COG2358@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3,Pkinase
SRR25158348_k127_428407_9	1125863.JAFN01000001_gene2910	7e-35	142.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158348_k127_428407_3	1121468.AUBR01000026_gene2918	7.294e-113	386.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158348_k127_428407_2	273068.TTE1356	4.609e-114	382.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,42FC8@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158348_k127_428407_0	234267.Acid_4251	1.785e-156	506.0	COG0001@1|root,COG0001@2|Bacteria,3Y3GA@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158348_k127_428407_8	1144275.COCOR_04001	2.662e-37	163.0	COG0515@1|root,COG0515@2|Bacteria	1144275.COCOR_04001|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158348_k127_428407_6	247490.KSU1_C1270	1.299e-46	194.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FGE-sulfatase,TPR_11
SRR25158348_k127_428407_7	439235.Dalk_1878	2.005e-45	181.0	COG2230@1|root,COG4797@1|root,COG2230@2|Bacteria,COG4797@2|Bacteria,1QU8H@1224|Proteobacteria,42NYA@68525|delta/epsilon subdivisions,2WT6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25
SRR25158348_k127_428407_10	709986.Deima_0356	1.143e-23	109.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16,RicinB_lectin_2
SRR25158348_k127_428815_1	1297742.A176_05427	2.689e-68	243.0	COG3384@1|root,COG3384@2|Bacteria,1RB6Z@1224|Proteobacteria,43ACS@68525|delta/epsilon subdivisions,2X5SK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158348_k127_428815_2	1121861.KB899910_gene663	1.367e-52	198.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
SRR25158348_k127_428815_3	1122179.KB890447_gene307	2.641e-48	190.0	COG0657@1|root,COG0657@2|Bacteria,4NHDX@976|Bacteroidetes,1INS5@117747|Sphingobacteriia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
SRR25158348_k127_428815_4	1123399.AQVE01000027_gene30	4.091e-05	56.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,460AB@72273|Thiotrichales	72273|Thiotrichales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158348_k127_428815_0	247490.KSU1_D0161	6.884e-76	278.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
SRR25158348_k127_430482_0	1449126.JQKL01000066_gene2091	5.701e-18	84.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,268GF@186813|unclassified Clostridiales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	Aminotran_5,GDC-P
SRR25158348_k127_430482_1	314230.DSM3645_05150	2.006e-11	74.0	COG1413@1|root,COG1413@2|Bacteria,2IZZR@203682|Planctomycetes	203682|Planctomycetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158348_k127_430482_2	1379698.RBG1_1C00001G1444	2.245e-09	66.0	COG1520@1|root,COG1520@2|Bacteria,2NQ6A@2323|unclassified Bacteria	2|Bacteria	KLT	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158348_k127_431322_4	452637.Oter_2790	1.628e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,46Z69@74201|Verrucomicrobia,3K8AP@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_431322_1	1094980.Mpsy_0389	1.717e-61	222.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2N9HJ@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158348_k127_431322_2	304371.MCP_2716	1.018e-59	211.0	COG1898@1|root,arCOG04188@2157|Archaea,2XWJQ@28890|Euryarchaeota,2NASX@224756|Methanomicrobia	224756|Methanomicrobia	M	WxcM-like, C-terminal	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158348_k127_431322_3	324602.Caur_0486	1.09e-51	198.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158348_k127_431322_0	693661.Arcve_1538	7.018e-234	737.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,245PG@183980|Archaeoglobi	183980|Archaeoglobi	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158348_k127_431844_0	1125863.JAFN01000001_gene2579	2.419e-76	266.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158348_k127_431844_1	1410676.JNKL01000017_gene1331	1.505e-41	158.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1Y48K@135624|Aeromonadales	135624|Aeromonadales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158348_k127_444966_0	762376.AXYL_05736	0.0001073	46.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VQ59@28216|Betaproteobacteria,3T3Q6@506|Alcaligenaceae	28216|Betaproteobacteria	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4
SRR25158348_k127_445533_0	1123242.JH636436_gene42	1.175e-59	227.0	COG5492@1|root,COG5492@2|Bacteria,2IXAJ@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
SRR25158348_k127_445533_1	595460.RRSWK_00819	2.027e-05	57.0	COG4102@1|root,COG4102@2|Bacteria,2IXKF@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158348_k127_446289_1	404589.Anae109_0582	9.103e-17	85.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158348_k127_446289_0	639030.JHVA01000001_gene1231	2.609e-75	262.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria,2JIHD@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158348_k127_446684_0	1499967.BAYZ01000103_gene3745	1.72e-81	286.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158348_k127_446684_2	1177928.TH2_20299	6.931e-19	91.0	COG2827@1|root,COG2827@2|Bacteria,1N04N@1224|Proteobacteria,2UCN4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	excinuclease ABC	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
SRR25158348_k127_446684_1	1229780.BN381_640021	5.132e-29	127.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,3UX27@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158348_k127_446684_5	1128421.JAGA01000002_gene1599	2.165e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158348_k127_446684_3	883080.HMPREF9697_03044	4.925e-09	70.0	2DQBG@1|root,335T7@2|Bacteria,1N795@1224|Proteobacteria	1224|Proteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
SRR25158348_k127_446684_6	1121918.ARWE01000001_gene3280	6.55e-06	59.0	2DREH@1|root,33BDY@2|Bacteria,1Q6K1@1224|Proteobacteria,433AU@68525|delta/epsilon subdivisions,2WXFM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_448352_6	1196323.ALKF01000188_gene4831	2.964e-12	66.0	COG0605@1|root,COG0605@2|Bacteria,1UZSR@1239|Firmicutes,4HCTK@91061|Bacilli,26UAR@186822|Paenibacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158348_k127_448352_0	1254432.SCE1572_38000	1.73e-179	571.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_448352_2	331869.BAL199_27406	1.515e-49	200.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,4BS9N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	YCII-related domain	MA20_04055	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158348_k127_448352_1	886293.Sinac_3107	7.402e-64	230.0	COG3795@1|root,COG3795@2|Bacteria,2IZ9F@203682|Planctomycetes	203682|Planctomycetes	K	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158348_k127_448352_4	316067.Geob_0068	1.422e-31	138.0	COG2365@1|root,COG2365@2|Bacteria,1N0NB@1224|Proteobacteria,43CF8@68525|delta/epsilon subdivisions,2X60D@28221|Deltaproteobacteria,43UY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
SRR25158348_k127_448352_5	886293.Sinac_2556	1.856e-29	137.0	COG0526@1|root,COG1331@1|root,COG0526@2|Bacteria,COG1331@2|Bacteria,2J28Y@203682|Planctomycetes	203682|Planctomycetes	CO	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158348_k127_448352_3	1121890.AUDO01000030_gene1018	3.481e-43	170.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia,2NYWA@237|Flavobacterium	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRR25158348_k127_451525_2	5888.CAK80119	0.000941	51.0	KOG2177@1|root,KOG4441@1|root,KOG2177@2759|Eukaryota,KOG4441@2759|Eukaryota,3ZBDW@5878|Ciliophora	5878|Ciliophora	O	Kelch	-	-	2.3.2.27	ko:K10448,ko:K12009	-	-	-	-	ko00000,ko01000,ko04121	-	-	-	Kelch_1,zf-B_box,zf-RING_2
SRR25158348_k127_451525_1	1123508.JH636453_gene5800	4.752e-11	74.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158348_k127_451525_0	1254432.SCE1572_08690	1.44e-163	528.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,43AKF@68525|delta/epsilon subdivisions,2X60H@28221|Deltaproteobacteria,2YZ4M@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158348_k127_457675_1	1370121.AUWS01000016_gene7004	1.873e-36	155.0	COG5586@1|root,COG5586@2|Bacteria,2GX58@201174|Actinobacteria,237WQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
SRR25158348_k127_457675_0	365044.Pnap_2875	1.799e-61	220.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WHDJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,Response_reg
SRR25158348_k127_457675_2	1121918.ARWE01000001_gene2188	3.493e-29	122.0	2DBEC@1|root,2Z8RY@2|Bacteria,1MXRI@1224|Proteobacteria,42ZNW@68525|delta/epsilon subdivisions,2WUUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
SRR25158348_k127_457888_6	1169152.AXVD01000003_gene4755	4.498e-07	53.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4FUSR@85025|Nocardiaceae	201174|Actinobacteria	CE	Tartrate dehydrogenase	dmlA	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
SRR25158348_k127_457888_0	247490.KSU1_D0781	2.402e-71	258.0	COG0534@1|root,COG0534@2|Bacteria,2IXGS@203682|Planctomycetes	203682|Planctomycetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158348_k127_457888_3	314230.DSM3645_27483	2.463e-53	206.0	COG0750@1|root,COG0793@1|root,COG2234@1|root,COG0750@2|Bacteria,COG0793@2|Bacteria,COG2234@2|Bacteria,2IXR2@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M28
SRR25158348_k127_457888_2	1121930.AQXG01000023_gene1633	1.597e-54	208.0	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
SRR25158348_k127_457888_4	1210884.HG799464_gene10830	5.826e-46	181.0	COG0352@1|root,COG0352@2|Bacteria,2IY16@203682|Planctomycetes	203682|Planctomycetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Clp_N,TMP-TENI
SRR25158348_k127_457888_1	1123508.JH636444_gene5501	2.216e-59	228.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
SRR25158348_k127_457888_5	1265505.ATUG01000001_gene4575	1.628e-15	87.0	2CD96@1|root,32XZD@2|Bacteria,1N5W5@1224|Proteobacteria,42UZ9@68525|delta/epsilon subdivisions,2WR27@28221|Deltaproteobacteria,2MKNA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_458105_0	483219.LILAB_30415	1.059e-24	117.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U6U@68525|delta/epsilon subdivisions,2WQS4@28221|Deltaproteobacteria,2YVQM@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158348_k127_458355_0	1232410.KI421414_gene2918	1.112e-84	299.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,43SK4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158348_k127_458355_1	1340493.JNIF01000003_gene4190	6.721e-24	105.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20,HTH_5
SRR25158348_k127_458355_2	1340493.JNIF01000003_gene4191	1.519e-14	80.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158348_k127_45917_1	314230.DSM3645_11831	9.639e-46	180.0	COG1657@1|root,COG1657@2|Bacteria,2IXAS@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
SRR25158348_k127_45917_0	931277.C448_05171	4.107e-83	287.0	COG1260@1|root,arCOG04213@2157|Archaea,2XUAV@28890|Euryarchaeota,23SA3@183963|Halobacteria	183963|Halobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158348_k127_460515_0	378806.STAUR_6910	1.891e-143	490.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158348_k127_460515_1	247490.KSU1_C0355	2.335e-118	392.0	COG1322@1|root,COG1322@2|Bacteria,2J2TY@203682|Planctomycetes	203682|Planctomycetes	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158348_k127_460515_3	367299.JOEE01000002_gene2645	1.216e-06	50.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4FH1X@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158348_k127_460515_2	1122222.AXWR01000026_gene1640	2.961e-15	77.0	COG3118@1|root,COG3118@2|Bacteria,1WK9V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158348_k127_460668_0	1123242.JH636436_gene647	4.268e-14	77.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
SRR25158348_k127_460668_1	1089545.KB913037_gene2590	0.0006617	51.0	COG3307@1|root,COG3307@2|Bacteria,2HISQ@201174|Actinobacteria,4DYMQ@85010|Pseudonocardiales	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158348_k127_461181_0	316274.Haur_1083	6.923e-34	142.0	COG0589@1|root,COG0745@1|root,COG0589@2|Bacteria,COG0745@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158348_k127_461181_2	502025.Hoch_1899	2.045e-11	76.0	COG2524@1|root,COG2524@2|Bacteria,1QANB@1224|Proteobacteria,43E2I@68525|delta/epsilon subdivisions,2WZHW@28221|Deltaproteobacteria,2Z26K@29|Myxococcales	28221|Deltaproteobacteria	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158348_k127_461181_1	697282.Mettu_3761	2.887e-24	118.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1S48Z@1236|Gammaproteobacteria,1XEJQ@135618|Methylococcales	135618|Methylococcales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158348_k127_463268_1	626887.J057_13316	5.784e-44	168.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1T478@1236|Gammaproteobacteria,46D9V@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158348_k127_463268_0	1267005.KB911266_gene1261	4.35e-203	644.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cnrA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR25158348_k127_464292_0	247490.KSU1_C0930	3.377e-226	725.0	COG1185@1|root,COG1185@2|Bacteria,2IWXZ@203682|Planctomycetes	203682|Planctomycetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158348_k127_464292_2	1123227.KB899336_gene292	4.259e-28	116.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,2JT89@204441|Rhodospirillales	204441|Rhodospirillales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158348_k127_464292_1	1408442.JADE01000005_gene1274	1.659e-40	166.0	COG1112@1|root,COG1112@2|Bacteria	2|Bacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	AAA_11,AAA_12,AAA_30,DEAD,Helicase_C
SRR25158348_k127_468041_5	1192034.CAP_1750	6.783e-15	81.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_468041_0	469383.Cwoe_3437	5.631e-140	453.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
SRR25158348_k127_468041_2	1206739.BAGJ01000099_gene1976	3.254e-40	152.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,4G0GD@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158348_k127_468041_1	667632.KB890164_gene2210	1.706e-42	164.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,2VSW8@28216|Betaproteobacteria,1K88Q@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
SRR25158348_k127_468041_3	1380391.JIAS01000015_gene78	5.676e-36	145.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria,2U953@28211|Alphaproteobacteria,2JUWV@204441|Rhodospirillales	204441|Rhodospirillales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158348_k127_468041_4	686340.Metal_2796	1.667e-17	87.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,1RGZF@1224|Proteobacteria,1S6GG@1236|Gammaproteobacteria,1XDM4@135618|Methylococcales	135618|Methylococcales	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,SpoIIE
SRR25158348_k127_47027_2	502025.Hoch_5058	1.031e-12	79.0	COG3794@1|root,COG3794@2|Bacteria,1Q2EH@1224|Proteobacteria,43807@68525|delta/epsilon subdivisions,2X3A8@28221|Deltaproteobacteria,2YV38@29|Myxococcales	28221|Deltaproteobacteria	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158348_k127_47027_1	1123228.AUIH01000018_gene3552	4.844e-34	133.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XKHD@135619|Oceanospirillales	135619|Oceanospirillales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158348_k127_47027_0	1156937.MFUM_930013	1.679e-180	573.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,37G43@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158348_k127_473352_0	1416752.AYME01000002_gene939	5.241e-58	220.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,4FM16@85023|Microbacteriaceae	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
SRR25158348_k127_480383_1	1210884.HG799462_gene7953	1.664e-86	293.0	COG0743@1|root,COG0743@2|Bacteria,2IY3M@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158348_k127_480383_0	1192034.CAP_5161	3.577e-131	439.0	COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,438H6@68525|delta/epsilon subdivisions,2X3RZ@28221|Deltaproteobacteria,2YWYQ@29|Myxococcales	28221|Deltaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158348_k127_480383_2	886293.Sinac_7299	3.644e-35	150.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2IY17@203682|Planctomycetes	203682|Planctomycetes	S	competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158348_k127_4807_1	768670.Calni_0322	7.222e-25	112.0	COG0839@1|root,COG0839@2|Bacteria,2GFCE@200930|Deferribacteres	200930|Deferribacteres	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158348_k127_4807_2	743722.Sph21_1597	8.93e-22	97.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1ISXN@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158348_k127_4807_0	1379698.RBG1_1C00001G1060	1.043e-149	499.0	COG1009@1|root,COG1009@2|Bacteria,2NNU6@2323|unclassified Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158348_k127_4807_3	1121445.ATUZ01000013_gene1330	0.0001157	47.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2M89W@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158348_k127_483834_0	530564.Psta_0999	2.632e-25	117.0	COG0652@1|root,COG0652@2|Bacteria,2IZQS@203682|Planctomycetes	203682|Planctomycetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
SRR25158348_k127_491496_3	794903.OPIT5_09835	2.961e-09	66.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158348_k127_491496_1	68223.JNZY01000037_gene7491	6.184e-36	143.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158348_k127_491496_0	1242864.D187_003284	7.461e-72	245.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158348_k127_491496_2	204669.Acid345_4127	3.147e-22	104.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158348_k127_491496_4	1210884.HG799462_gene8495	6.915e-08	64.0	2EAYX@1|root,334ZU@2|Bacteria,2J0ZQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_491496_5	1283299.AUKG01000003_gene248	6.21e-05	55.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4CQMC@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158348_k127_492131_1	234267.Acid_1013	3.4e-56	200.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria	57723|Acidobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158348_k127_492131_0	237368.SCABRO_02658	9.242e-130	421.0	COG0013@1|root,COG0013@2|Bacteria,2IX30@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158348_k127_494817_2	1210884.HG799465_gene11488	1.865e-08	68.0	COG1277@1|root,COG1277@2|Bacteria,2IY6H@203682|Planctomycetes	203682|Planctomycetes	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158348_k127_494817_0	886293.Sinac_0578	7.258e-95	319.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_494817_1	1157490.EL26_17620	7.716e-20	105.0	COG0318@1|root,COG0318@2|Bacteria,1V2NE@1239|Firmicutes,4HBPA@91061|Bacilli,278Y3@186823|Alicyclobacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_497515_0	886293.Sinac_4905	4.873e-54	214.0	COG0515@1|root,COG2203@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,2J4MW@203682|Planctomycetes	203682|Planctomycetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	GAF
SRR25158348_k127_497515_1	997346.HMPREF9374_3634	1.049e-42	169.0	COG3253@1|root,COG3253@2|Bacteria,1VZPB@1239|Firmicutes,4HZ7E@91061|Bacilli,27B36@186824|Thermoactinomycetaceae	91061|Bacilli	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158348_k127_497515_2	419947.MRA_1188	4.841e-29	118.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,239CP@1762|Mycobacteriaceae	201174|Actinobacteria	C	ferredoxin	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
SRR25158348_k127_497515_3	886293.Sinac_1574	3.261e-24	103.0	COG2146@1|root,COG2146@2|Bacteria,2J0ZZ@203682|Planctomycetes	203682|Planctomycetes	P	COG2146 Ferredoxin subunits of nitrite reductase and	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158348_k127_499837_2	1286631.X805_29160	4.685e-05	54.0	COG1107@1|root,COG1107@2|Bacteria	2|Bacteria	L	ribosomal small subunit biogenesis	-	-	-	ko:K02945,ko:K07463	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Antiterm,HTH_30,S1
SRR25158348_k127_499837_1	634500.EbC_09630	3.972e-05	53.0	COG4380@1|root,COG4380@2|Bacteria,1R3WM@1224|Proteobacteria,1RSP7@1236|Gammaproteobacteria,3X6FP@551|Erwinia	1236|Gammaproteobacteria	M	Putative bacterial lipoprotein (DUF799)	VY92_06375	-	-	-	-	-	-	-	-	-	-	-	DUF799
SRR25158348_k127_504896_0	247490.KSU1_C0933	2.503e-149	484.0	COG2204@1|root,COG2204@2|Bacteria,2IWYY@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_504896_1	237368.SCABRO_02976	1.357e-56	207.0	COG5000@1|root,COG5000@2|Bacteria,2IZCJ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158348_k127_505800_2	1123508.JH636443_gene4859	5.94e-07	63.0	COG3147@1|root,COG3147@2|Bacteria,2IYA2@203682|Planctomycetes	203682|Planctomycetes	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_505800_3	105422.BBPM01000028_gene3908	0.0006373	44.0	2B75U@1|root,3207M@2|Bacteria,2I1G0@201174|Actinobacteria,2NJS7@228398|Streptacidiphilus	201174|Actinobacteria	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR25158348_k127_505800_0	1254432.SCE1572_52300	6.732e-121	402.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WNH1@28221|Deltaproteobacteria,2Z329@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158348_k127_505800_1	1210884.HG799465_gene11914	5.231e-88	297.0	COG0008@1|root,COG0008@2|Bacteria,2IYG3@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158348_k127_508125_0	1137799.GZ78_24255	2.662e-13	72.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1XKYP@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158348_k127_508658_2	1511.CLOST_0585	2.758e-11	77.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,25QPY@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Periplasmic, score	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158348_k127_508658_0	518766.Rmar_2245	6.725e-119	416.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158348_k127_508658_1	518766.Rmar_0925	9.854e-64	232.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158348_k127_510298_3	379066.GAU_3660	1.121e-09	63.0	COG2318@1|root,COG2318@2|Bacteria,1ZU5V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158348_k127_510298_4	1121938.AUDY01000007_gene2501	2.197e-05	50.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_510298_1	330214.NIDE1725	3.607e-23	111.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158348_k127_510298_0	1454004.AW11_00930	1.114e-47	181.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,2WC2P@28216|Betaproteobacteria,1KR2C@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_510298_2	886293.Sinac_2378	1.042e-11	77.0	COG2911@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2982@2|Bacteria,2J50C@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_511526_3	886293.Sinac_5599	1.937e-83	300.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158348_k127_511526_4	575540.Isop_0751	3.195e-77	286.0	COG1043@1|root,COG1043@2|Bacteria,2IYJJ@203682|Planctomycetes	203682|Planctomycetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158348_k127_511526_0	1142394.PSMK_05870	1.073e-104	370.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2IZ4S@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108,4.2.1.59	ko:K02535,ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
SRR25158348_k127_511526_2	401526.TcarDRAFT_0093	1.601e-83	289.0	COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,4H1ZV@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158348_k127_511526_1	237368.SCABRO_01911	1.05e-99	353.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158348_k127_512046_1	335543.Sfum_1981	6.203e-50	187.0	COG1082@1|root,COG1082@2|Bacteria,1Q7WK@1224|Proteobacteria,437EM@68525|delta/epsilon subdivisions,2X2KW@28221|Deltaproteobacteria,2MR9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158348_k127_512046_0	880073.Calab_0681	4.918e-50	195.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
SRR25158348_k127_512046_4	1121385.AQXW01000004_gene2360	1.431e-06	57.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1ZVUS@145357|Dermacoccaceae	201174|Actinobacteria	K	Crp-like helix-turn-helix domain	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158348_k127_512046_2	929562.Emtol_1661	1.509e-43	173.0	COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,47JFG@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_512046_3	264732.Moth_2363	3.392e-07	63.0	COG5662@1|root,COG5662@2|Bacteria,1VC8Y@1239|Firmicutes,24NRN@186801|Clostridia,42GY2@68295|Thermoanaerobacterales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
SRR25158348_k127_515238_3	1142394.PSMK_25870	1.071e-05	56.0	COG2304@1|root,COG2304@2|Bacteria,2IYNV@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158348_k127_515238_0	247490.KSU1_B0387	3.823e-133	438.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158348_k127_515238_2	1123242.JH636435_gene2006	1.173e-09	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
SRR25158348_k127_515238_4	314230.DSM3645_22836	0.0004832	49.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
SRR25158348_k127_515238_1	1158292.JPOE01000002_gene3874	3.458e-27	115.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,1KMAJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158348_k127_517649_0	521674.Plim_2811	5.27e-134	436.0	COG1060@1|root,COG1060@2|Bacteria,2IX1I@203682|Planctomycetes	203682|Planctomycetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158348_k127_517649_2	469383.Cwoe_3370	5.612e-08	64.0	COG3055@1|root,COG3055@2|Bacteria,2I91M@201174|Actinobacteria,4CS1X@84995|Rubrobacteria	84995|Rubrobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
SRR25158348_k127_517649_1	237368.SCABRO_03057	3.046e-85	296.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_519231_0	886293.Sinac_5965	5.129e-82	280.0	COG0526@1|root,COG2010@1|root,COG0526@2|Bacteria,COG2010@2|Bacteria,2IWVQ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C
SRR25158348_k127_523668_1	70448.A0A090M583	0.0001062	51.0	COG0457@1|root,KOG1124@2759|Eukaryota,37PIA@33090|Viridiplantae,34H83@3041|Chlorophyta	3041|Chlorophyta	S	PsbB mRNA maturation factor Mbb1	MBB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	ko:K20310	-	-	-	-	ko00000,ko04131	-	-	-	TPR_16,TPR_8
SRR25158348_k127_523668_0	511062.GU3_08770	4.967e-37	147.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1Y6DR@135624|Aeromonadales	135624|Aeromonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158348_k127_527973_2	867845.KI911784_gene2774	2.376e-12	81.0	COG1413@1|root,COG1674@1|root,COG5635@1|root,COG1413@2|Bacteria,COG1674@2|Bacteria,COG5635@2|Bacteria,2G8R0@200795|Chloroflexi,3766B@32061|Chloroflexia	32061|Chloroflexia	CDT	Armadillo/beta-catenin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158348_k127_527973_0	1227453.C444_18042	1.392e-68	244.0	COG0179@1|root,arCOG00235@2157|Archaea,2XT1S@28890|Euryarchaeota,23S3T@183963|Halobacteria	183963|Halobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158348_k127_527973_1	1121930.AQXG01000009_gene288	1.114e-14	75.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1IPV4@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158348_k127_532277_1	688269.Theth_1211	1.558e-125	414.0	COG1473@1|root,COG1473@2|Bacteria,2GCJT@200918|Thermotogae	200918|Thermotogae	S	peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158348_k127_532277_3	234267.Acid_7401	8.169e-58	223.0	2CAZH@1|root,2Z7RU@2|Bacteria,3Y4WA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158348_k127_532277_0	234267.Acid_7402	0.0	1071.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria	57723|Acidobacteria	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158348_k127_532277_2	316274.Haur_1732	2.644e-119	396.0	COG0479@1|root,COG0479@2|Bacteria,2GACG@200795|Chloroflexi,3758X@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158348_k127_53252_0	1210884.HG799466_gene12425	3.331e-99	341.0	COG0714@1|root,COG0714@2|Bacteria,2IXS7@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158348_k127_533398_0	330214.NIDE2086	1.626e-42	170.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158348_k127_534007_5	266117.Rxyl_1153	4.483e-08	60.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158348_k127_534007_2	1121121.KB894291_gene1370	1.128e-27	125.0	2DSG0@1|root,33G08@2|Bacteria,1VWUE@1239|Firmicutes,4HX3M@91061|Bacilli,26XS6@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF4241)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241
SRR25158348_k127_534007_4	76114.ebA5156	2.349e-12	80.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,2KWVW@206389|Rhodocyclales	206389|Rhodocyclales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158348_k127_534007_6	1348114.OM33_08245	8.545e-05	51.0	COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,2Q13H@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG4772 Outer membrane receptor for Fe3 -dicitrate	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	Plug,TonB_dep_Rec
SRR25158348_k127_534007_1	1403819.BATR01000162_gene5396	2.154e-34	142.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase,Polyketide_cyc2
SRR25158348_k127_534007_3	1038866.KB902775_gene5327	6.072e-14	76.0	2E328@1|root,32Y2G@2|Bacteria,1N9RI@1224|Proteobacteria,2UFJ4@28211|Alphaproteobacteria,3K0VA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_534007_0	671143.DAMO_0396	2.681e-175	569.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158348_k127_535093_1	247490.KSU1_C1209	6.589e-52	190.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158348_k127_535093_3	156889.Mmc1_0849	1.251e-17	85.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2UBQ1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158348_k127_535093_0	247490.KSU1_C1211	6.713e-107	353.0	COG0090@1|root,COG0090@2|Bacteria,2IXD9@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158348_k127_535093_2	1123508.JH636455_gene17	8.962e-31	131.0	COG0185@1|root,COG0185@2|Bacteria,2J0BB@203682|Planctomycetes	203682|Planctomycetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158348_k127_535093_4	237368.SCABRO_03501	2.996e-16	87.0	COG0091@1|root,COG0091@2|Bacteria,2J023@203682|Planctomycetes	203682|Planctomycetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158348_k127_535093_5	595460.RRSWK_06895	1.152e-14	74.0	COG0092@1|root,COG0092@2|Bacteria,2IWWU@203682|Planctomycetes	203682|Planctomycetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158348_k127_53534_0	1121405.dsmv_1899	7.099e-103	341.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2MIW0@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM pyruvate carboxyltransferase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158348_k127_53534_1	1378168.N510_00187	1.521e-16	85.0	COG4770@1|root,COG5016@1|root,COG4770@2|Bacteria,COG5016@2|Bacteria	2|Bacteria	C	pyruvate	oadA	-	2.1.3.1,4.1.1.3,6.4.1.1,6.4.1.7	ko:K01571,ko:K01960,ko:K03416,ko:K20140	ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344,R00353,R00930	RC00040,RC00097,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	iJN746.PP_5346,iLJ478.TM0128	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158348_k127_53534_2	1416752.AYME01000003_gene2797	2.973e-11	67.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4FQZ7@85023|Microbacteriaceae	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158348_k127_5368_1	237368.SCABRO_03510	2.143e-116	383.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2IWX5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158348_k127_5368_3	886293.Sinac_7029	1.049e-96	327.0	COG1226@1|root,COG1226@2|Bacteria,2J121@203682|Planctomycetes	203682|Planctomycetes	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
SRR25158348_k127_5368_0	886293.Sinac_1836	6.669e-141	461.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158348_k127_5368_2	575540.Isop_3543	6.597e-99	331.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158348_k127_5368_5	886293.Sinac_1838	6.94e-70	264.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158348_k127_5368_4	1303518.CCALI_02531	4.447e-77	288.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria	2|Bacteria	D	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA,VWA_2
SRR25158348_k127_5368_6	485914.Hmuk_0677	2.555e-05	58.0	COG1520@1|root,arCOG02556@2157|Archaea,2Y7Q9@28890|Euryarchaeota,240XC@183963|Halobacteria	183963|Halobacteria	C	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158348_k127_536890_2	177439.DP2764	1.175e-06	55.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria,2MJZD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR25158348_k127_536890_1	1280664.AUIX01000001_gene617	1.04e-08	65.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,4BZ07@830|Butyrivibrio	186801|Clostridia	NU	Type II secretion system (T2SS), protein E, N-terminal domain	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158348_k127_536890_3	497964.CfE428DRAFT_4830	1.986e-06	59.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	2.4.1.187	ko:K04749,ko:K05946,ko:K06378	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003,ko03021	-	GT26	-	STAS,STAS_2
SRR25158348_k127_536890_4	457424.BFAG_00226	2.126e-06	60.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,2FUQY@200643|Bacteroidia,4ARR2@815|Bacteroidaceae	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158348_k127_536890_0	1379698.RBG1_1C00001G1764	1.108e-12	69.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158348_k127_539531_2	1540221.JQNI01000004_gene326	4.525e-42	163.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158348_k127_539531_1	1166018.FAES_4253	4.097e-46	176.0	29SM0@1|root,30DSB@2|Bacteria,4NQ72@976|Bacteroidetes,47QJW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158348_k127_539531_0	314230.DSM3645_04705	2.862e-113	375.0	COG0150@1|root,COG0150@2|Bacteria,2IYCG@203682|Planctomycetes	203682|Planctomycetes	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158348_k127_539531_3	177439.DP0259	2.165e-38	147.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MI1E@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158348_k127_541853_0	234267.Acid_5757	4.531e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,3Y8YQ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_541853_1	1210884.HG799466_gene12508	9.199e-12	76.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158348_k127_541853_2	595494.Tola_1191	0.0003338	46.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
SRR25158348_k127_548283_4	1150469.RSPPHO_02781	0.0002535	46.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_548283_1	1125863.JAFN01000001_gene568	4.739e-160	515.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
SRR25158348_k127_548283_3	649638.Trad_1380	3.998e-30	136.0	COG4365@1|root,COG4365@2|Bacteria,1WIHE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
SRR25158348_k127_548283_2	648996.Theam_0155	1.024e-65	238.0	COG1060@1|root,COG1060@2|Bacteria,2G3U8@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158348_k127_548283_0	518766.Rmar_1349	1.996e-231	746.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1FJ68@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158348_k127_54969_0	562970.Btus_1313	1.252e-153	491.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,277YF@186823|Alicyclobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158348_k127_54969_1	714943.Mucpa_3111	1.425e-17	89.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1ITD7@117747|Sphingobacteriia	976|Bacteroidetes	I	Biotin lipoyl attachment domain-containing protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
SRR25158348_k127_558222_1	1192034.CAP_8119	1.412e-51	209.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
SRR25158348_k127_558222_0	471854.Dfer_3146	3.396e-61	239.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
SRR25158348_k127_558222_2	204669.Acid345_2119	1.774e-30	124.0	COG0727@1|root,COG0727@2|Bacteria,3Y4VW@57723|Acidobacteria,2JJKG@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158348_k127_56081_1	653733.Selin_2486	3.432e-44	164.0	COG0745@1|root,COG0745@2|Bacteria	653733.Selin_2486|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_56081_3	1408445.JHXP01000018_gene3429	9.522e-06	52.0	COG2199@1|root,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,1JGJP@118969|Legionellales	118969|Legionellales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
SRR25158348_k127_56081_0	502025.Hoch_3320	1.379e-90	311.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158348_k127_56081_2	378806.STAUR_6695	1.698e-18	99.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	1.14.13.142,1.17.1.1	ko:K00523,ko:K15983	ko00520,ko00984,ko01100,ko01120,map00520,map00984,map01100,map01120	-	R03391,R03392,R09860	RC00230,RC02691	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,FAD_binding_8,Ferric_reduct,NAD_binding_1
SRR25158348_k127_563347_3	926569.ANT_05570	8.995e-24	112.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158348_k127_563347_0	1385514.N782_12985	2.813e-117	391.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2Y8N8@289201|Pontibacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158348_k127_563347_1	1380355.JNIJ01000014_gene564	4.338e-90	303.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VF1S@28211|Alphaproteobacteria,3K6DC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158348_k127_563347_2	97138.C820_00313	9.584e-25	108.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,36HY3@31979|Clostridiaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rotA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158348_k127_564269_4	338963.Pcar_2064	2.884e-06	50.0	COG2261@1|root,COG2261@2|Bacteria,1NE11@1224|Proteobacteria	1224|Proteobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158348_k127_564269_1	96561.Dole_2966	1.849e-29	126.0	2C5AX@1|root,33J9J@2|Bacteria,1NNQH@1224|Proteobacteria,433PI@68525|delta/epsilon subdivisions,2WY12@28221|Deltaproteobacteria,2MP9G@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_564269_2	1173020.Cha6605_4029	1.515e-10	71.0	COG3806@1|root,COG3806@2|Bacteria,1GQVU@1117|Cyanobacteria	1117|Cyanobacteria	T	ChrR Cupin-like domain	-	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7
SRR25158348_k127_564269_3	337191.KTR9_4026	1.023e-07	62.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4GDXE@85026|Gordoniaceae	201174|Actinobacteria	K	ECF sigma factor	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158348_k127_564269_0	391625.PPSIR1_26006	1.579e-50	199.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,434NC@68525|delta/epsilon subdivisions,2WYZN@28221|Deltaproteobacteria,2Z10G@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158348_k127_565258_0	743299.Acife_2415	1.933e-10	72.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,2NCVA@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158348_k127_565258_2	1006000.GKAS_04471	0.0006946	51.0	COG0607@1|root,COG0607@2|Bacteria,1RDIR@1224|Proteobacteria,1S3VJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	SMART Rhodanese domain protein	ygaP	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
SRR25158348_k127_565258_1	7719.XP_009857433.1	0.0001873	51.0	KOG1218@1|root,KOG1218@2759|Eukaryota,39M98@33154|Opisthokonta,3CNWB@33208|Metazoa,3DE1B@33213|Bilateria	33208|Metazoa	T	engulfment of apoptotic cell	-	GO:0000132,GO:0000226,GO:0000278,GO:0001845,GO:0001891,GO:0003002,GO:0003674,GO:0005044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006897,GO:0006898,GO:0006909,GO:0006910,GO:0006911,GO:0006915,GO:0006950,GO:0006952,GO:0006986,GO:0006996,GO:0007010,GO:0007017,GO:0007033,GO:0007040,GO:0007049,GO:0007163,GO:0007275,GO:0007389,GO:0008037,GO:0008104,GO:0008150,GO:0008219,GO:0009605,GO:0009607,GO:0009617,GO:0009798,GO:0009986,GO:0009987,GO:0010033,GO:0010324,GO:0010941,GO:0010942,GO:0012501,GO:0012506,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0022402,GO:0022607,GO:0030010,GO:0030029,GO:0030036,GO:0030100,GO:0030139,GO:0030334,GO:0030335,GO:0030659,GO:0030666,GO:0030670,GO:0031090,GO:0031143,GO:0031253,GO:0031260,GO:0031410,GO:0031532,GO:0031982,GO:0032501,GO:0032502,GO:0032879,GO:0033036,GO:0033554,GO:0034620,GO:0035966,GO:0035967,GO:0038024,GO:0040001,GO:0040012,GO:0040017,GO:0042221,GO:0042742,GO:0042981,GO:0042995,GO:0043065,GO:0043067,GO:0043068,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043277,GO:0043652,GO:0043654,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045335,GO:0045807,GO:0048518,GO:0048522,GO:0048856,GO:0050764,GO:0050766,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051270,GO:0051272,GO:0051293,GO:0051294,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051704,GO:0051707,GO:0051716,GO:0060099,GO:0060100,GO:0060627,GO:0060972,GO:0061024,GO:0065007,GO:0070887,GO:0070925,GO:0070986,GO:0071310,GO:0071840,GO:0071944,GO:0080171,GO:0090382,GO:0097708,GO:0098542,GO:0098588,GO:0098590,GO:0098657,GO:0098805,GO:0099024,GO:0120025,GO:0120038,GO:1901074,GO:1901076,GO:1902742,GO:1902850,GO:1903047,GO:1903354,GO:1903356,GO:1904747,GO:1904748,GO:1905153,GO:1905155,GO:2000145,GO:2000147,GO:2000425,GO:2000427	-	-	-	-	-	-	-	-	-	-	Laminin_EGF
SRR25158348_k127_565338_2	204669.Acid345_3238	1.916e-27	112.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	MA20_26500	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158348_k127_565338_3	272134.KB731326_gene355	7.325e-26	110.0	COG0640@1|root,COG0640@2|Bacteria,1G83I@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158348_k127_565338_4	1125863.JAFN01000001_gene1466	3.749e-18	97.0	COG4313@1|root,COG4313@2|Bacteria,1N1DR@1224|Proteobacteria,432MC@68525|delta/epsilon subdivisions,2WXBW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_565338_0	1041930.Mtc_2388	3.222e-132	428.0	COG0863@1|root,arCOG00115@2157|Archaea,2Y8E2@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158348_k127_565338_7	1211115.ALIQ01000230_gene1658	0.0001736	54.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3NAFH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	Trypsin	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR25158348_k127_565338_6	1122180.Lokhon_02621	1.21e-05	57.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2P7WF@245186|Loktanella	28211|Alphaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR25158348_k127_565338_5	1499967.BAYZ01000159_gene502	8.365e-11	69.0	COG2203@1|root,COG2208@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3437@2|Bacteria,2NQW9@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3,4.6.1.1	ko:K01079,ko:K01768,ko:K07315	ko00230,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko02025,ko04113,ko04213,map00230,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map02025,map04113,map04213	M00020,M00695	R00089,R00434,R00582	RC00017,RC00295	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HATPase_c_2,Response_reg,SSF,SpoIIE
SRR25158348_k127_565338_1	1283299.AUKG01000002_gene3795	2.395e-68	247.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4CP76@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158348_k127_565623_1	1501230.ET33_29485	1.73e-17	96.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,26QZT@186822|Paenibacillaceae	91061|Bacilli	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158348_k127_565623_0	1183438.GKIL_1167	7.276e-147	477.0	COG0436@1|root,COG0436@2|Bacteria,1G202@1117|Cyanobacteria	1117|Cyanobacteria	E	Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158348_k127_565623_2	140626.JHWB01000009_gene1117	2.978e-14	73.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158348_k127_567042_0	1219077.VAZ01S_023_00660	1.116e-24	113.0	COG3451@1|root,COG3451@2|Bacteria,1MUEN@1224|Proteobacteria,1RMMX@1236|Gammaproteobacteria,1XVTE@135623|Vibrionales	135623|Vibrionales	U	F pilus assembly Type-IV secretion system for plasmid transfer	traC	-	-	ko:K12063	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AAA_10,TraC_F_IV
SRR25158348_k127_571504_6	748449.Halha_0666	1.609e-09	66.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia,3WAC8@53433|Halanaerobiales	186801|Clostridia	N	TIGRFAM flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
SRR25158348_k127_571504_1	497964.CfE428DRAFT_0262	1.369e-46	176.0	COG0688@1|root,COG0688@2|Bacteria,46VRI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158348_k127_571504_5	1123508.JH636439_gene1031	7.418e-39	156.0	COG1183@1|root,COG1183@2|Bacteria,2IZHR@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158348_k127_571504_4	997346.HMPREF9374_2723	4.479e-39	160.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,27C3R@186824|Thermoactinomycetaceae	91061|Bacilli	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158348_k127_571504_0	1121468.AUBR01000008_gene2061	3.084e-93	322.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158348_k127_571504_2	1125863.JAFN01000001_gene2765	1.046e-41	165.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158348_k127_571504_3	247490.KSU1_D1034	2.413e-40	159.0	COG2088@1|root,COG2088@2|Bacteria,2IZR8@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SpoVG family	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
SRR25158348_k127_577213_1	1458427.BAWN01000032_gene1800	4.8e-08	55.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,4A9UT@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_577213_0	644282.Deba_1067	8.459e-101	349.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158348_k127_577213_2	671143.DAMO_1095	0.0007747	43.0	COG1392@1|root,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	MA20_27875	-	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158348_k127_577918_2	316067.Geob_3238	3.719e-13	74.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,43TN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158348_k127_577918_0	448385.sce7170	1.089e-247	781.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,42MKI@68525|delta/epsilon subdivisions,2WM5H@28221|Deltaproteobacteria,2YZJV@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3459)	treZ-2	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158348_k127_577918_1	1463841.JOIR01000048_gene2865	3.167e-18	90.0	COG5592@1|root,COG5592@2|Bacteria,2IGW0@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158348_k127_580139_1	1249627.D779_3053	1.773e-14	77.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,1S623@1236|Gammaproteobacteria,1WYM3@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158348_k127_580139_0	269799.Gmet_1669	4.995e-149	495.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158348_k127_581882_0	264732.Moth_1478	3.573e-67	233.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,42G7G@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM response regulator receiver	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_581882_1	269799.Gmet_3382	5.633e-65	246.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,43BSP@68525|delta/epsilon subdivisions,2X7EK@28221|Deltaproteobacteria,43W43@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158348_k127_581882_2	1196323.ALKF01000110_gene5157	1.521e-48	199.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,26U61@186822|Paenibacillaceae	91061|Bacilli	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158348_k127_582394_1	1396141.BATP01000007_gene5740	2.636e-25	106.0	COG4251@1|root,COG4251@2|Bacteria,46W3X@74201|Verrucomicrobia	74201|Verrucomicrobia	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
SRR25158348_k127_582394_2	1101190.ARWB01000001_gene2810	5.692e-23	105.0	COG4251@1|root,COG4251@2|Bacteria,1NJ99@1224|Proteobacteria,2UUQ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PFAM KaiB domain protein	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
SRR25158348_k127_582394_0	215803.DB30_4171	7.63e-86	310.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1RKH1@1224|Proteobacteria,43BZT@68525|delta/epsilon subdivisions,2X4N0@28221|Deltaproteobacteria,2YZ9Z@29|Myxococcales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
SRR25158348_k127_582394_4	794903.OPIT5_27940	2.029e-11	73.0	COG1595@1|root,COG1595@2|Bacteria,46YS4@74201|Verrucomicrobia,3K8W5@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158348_k127_582394_3	861299.J421_3061	1.146e-15	89.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
SRR25158348_k127_582394_5	1278307.KB906976_gene1564	2.198e-07	59.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158348_k127_583788_0	324602.Caur_0055	5.33e-19	103.0	COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158348_k127_583788_2	593117.TGAM_1390	3.199e-08	62.0	COG4945@1|root,arCOG03264@1|root,arCOG01310@2157|Archaea,arCOG03264@2157|Archaea,arCOG03771@2157|Archaea,2XSTV@28890|Euryarchaeota,245KU@183968|Thermococci	183968|Thermococci	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,PEGA
SRR25158348_k127_583788_1	1254432.SCE1572_08950	1.725e-15	78.0	COG3865@1|root,COG5507@1|root,COG3865@2|Bacteria,COG5507@2|Bacteria,1N7IY@1224|Proteobacteria,42QW0@68525|delta/epsilon subdivisions,2WMZW@28221|Deltaproteobacteria,2YV61@29|Myxococcales	28221|Deltaproteobacteria	H	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
SRR25158348_k127_590287_0	349161.Dred_1666	9.343e-122	401.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,260AS@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158348_k127_590287_1	234267.Acid_1455	5.532e-47	194.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,3Y46R@57723|Acidobacteria	57723|Acidobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PDZ_2,Peptidase_M28
SRR25158348_k127_592756_1	404589.Anae109_3101	1.67e-51	189.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158348_k127_592756_0	1210884.HG799462_gene8794	8.969e-101	350.0	COG4191@1|root,COG4191@2|Bacteria,2J2PC@203682|Planctomycetes	203682|Planctomycetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158348_k127_592756_2	497964.CfE428DRAFT_3583	4.547e-48	193.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
SRR25158348_k127_592756_3	1242864.D187_005528	6.635e-09	61.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,438ST@68525|delta/epsilon subdivisions,2X9CS@28221|Deltaproteobacteria,2YXPE@29|Myxococcales	28221|Deltaproteobacteria	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_593530_0	886293.Sinac_4981	1.756e-111	375.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
SRR25158348_k127_593530_1	517418.Ctha_0318	3.168e-96	321.0	COG1131@1|root,COG1131@2|Bacteria,1FDTT@1090|Chlorobi	2|Bacteria	V	PFAM ABC transporter related	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
SRR25158348_k127_593530_3	935837.JAEK01000083_gene573	4.861e-05	51.0	2ESZS@1|root,33KHZ@2|Bacteria,1VNY1@1239|Firmicutes,4HNS1@91061|Bacilli,1ZKNT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_593530_2	575540.Isop_1360	1.956e-70	250.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158348_k127_594684_0	1906.SFRA_20540	2.275e-33	142.0	arCOG02075@1|root,33AGA@2|Bacteria	2|Bacteria	S	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrS
SRR25158348_k127_594684_1	1128421.JAGA01000001_gene2095	5.932e-18	89.0	2E3MN@1|root,32YJW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_594684_2	713587.THITH_08945	3.441e-16	82.0	COG5002@1|root,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,1T3TP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c
SRR25158348_k127_59555_5	1397528.Q671_09895	2.179e-09	70.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1SB4C@1236|Gammaproteobacteria,1XQ58@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158348_k127_59555_3	472175.EL18_01086	2.848e-12	80.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,43KD9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158348_k127_59555_0	237368.SCABRO_00573	1.893e-50	184.0	COG0537@1|root,COG0537@2|Bacteria,2IZTG@203682|Planctomycetes	203682|Planctomycetes	FG	COGs COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158348_k127_59555_1	572478.Vdis_1921	7.028e-46	176.0	COG1028@1|root,arCOG01259@2157|Archaea	2157|Archaea	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158348_k127_59555_2	926554.KI912633_gene3975	2.253e-27	124.0	COG0603@1|root,COG0603@2|Bacteria,1WIP4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR25158348_k127_59555_4	931627.MycrhDRAFT_4181	2.481e-10	73.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria,235MW@1762|Mycobacteriaceae	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158348_k127_601035_1	1142394.PSMK_15110	2.228e-10	73.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SRR25158348_k127_601035_2	1173028.ANKO01000089_gene3663	2.432e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,1G7GF@1117|Cyanobacteria,1HDZM@1150|Oscillatoriales	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	LRV
SRR25158348_k127_601035_0	1122129.AUEF01000008_gene2025	2.088e-15	76.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,4H1F5@90964|Staphylococcaceae	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158348_k127_601445_1	401053.AciPR4_0132	1.764e-120	395.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158348_k127_601445_3	243233.MCA1270	6.52e-52	189.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1XECX@135618|Methylococcales	135618|Methylococcales	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158348_k127_601445_2	945713.IALB_2899	7.237e-55	197.0	28NYH@1|root,2ZBVN@2|Bacteria	2|Bacteria	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
SRR25158348_k127_601445_4	1183438.GKIL_1934	1.967e-47	188.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158348_k127_601445_0	1042209.HK44_007330	7.09e-145	464.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1YMXS@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Cysteine desulfurase	sufS	-	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
SRR25158348_k127_607916_1	1123008.KB905694_gene1500	3.963e-48	181.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia,22XAT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158348_k127_607916_3	1210884.HG799462_gene8495	3.616e-07	62.0	2EAYX@1|root,334ZU@2|Bacteria,2J0ZQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_607916_0	700598.Niako_0486	1.239e-67	254.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158348_k127_607916_4	1210884.HG799462_gene7805	1.097e-05	57.0	2EAYX@1|root,334ZU@2|Bacteria,2J0ZQ@203682|Planctomycetes	1210884.HG799462_gene7805|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_607916_2	1121335.Clst_1837	7.737e-21	96.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158348_k127_608480_1	1304885.AUEY01000034_gene1878	2.355e-09	67.0	COG2203@1|root,COG3829@1|root,COG3852@1|root,COG4191@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
SRR25158348_k127_608480_0	350058.Mvan_2912	1.114e-29	132.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,235TR@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158348_k127_608480_2	68199.JNZO01000002_gene1325	1.347e-07	57.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158348_k127_611503_0	215803.DB30_1485	3.484e-198	631.0	COG2931@1|root,COG2931@2|Bacteria,1QX4P@1224|Proteobacteria,439K8@68525|delta/epsilon subdivisions,2X4WY@28221|Deltaproteobacteria,2YZS2@29|Myxococcales	28221|Deltaproteobacteria	Q	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158348_k127_611503_1	395964.KE386496_gene323	3.239e-33	131.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2U1CS@28211|Alphaproteobacteria,3NBI4@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158348_k127_611519_0	448385.sce7278	1.777e-141	454.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YU40@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158348_k127_611519_1	1379698.RBG1_1C00001G0712	2.624e-96	334.0	COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158348_k127_611519_2	1379698.RBG1_1C00001G0711	9.723e-76	268.0	COG0612@1|root,COG0612@2|Bacteria,2NQHV@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	ymxG	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158348_k127_611729_10	243090.RB11988	2.049e-19	92.0	COG0515@1|root,COG0515@2|Bacteria	243090.RB11988|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_611729_4	1278073.MYSTI_04285	1.267e-114	381.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,42MA1@68525|delta/epsilon subdivisions,2WPWQ@28221|Deltaproteobacteria,2Z1GV@29|Myxococcales	28221|Deltaproteobacteria	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158348_k127_611729_0	1122182.KB903825_gene875	4.245e-213	677.0	COG0436@1|root,COG0436@2|Bacteria,2I9CX@201174|Actinobacteria,4DA33@85008|Micromonosporales	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158348_k127_611729_6	278957.ABEA03000085_gene2580	4.224e-98	335.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
SRR25158348_k127_611729_5	497964.CfE428DRAFT_6197	3.659e-102	355.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
SRR25158348_k127_611729_3	1449065.JMLL01000012_gene3738	8.301e-133	442.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2U1RU@28211|Alphaproteobacteria,43MQW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted Permease Membrane Region	-	-	-	-	-	-	-	-	-	-	-	-	Asp-Al_Ex,TrkA_C
SRR25158348_k127_611729_1	929556.Solca_2045	1.568e-193	619.0	COG2985@1|root,COG2985@2|Bacteria,4NHM3@976|Bacteroidetes,1J06S@117747|Sphingobacteriia	976|Bacteroidetes	U	Predicted Permease Membrane Region	aspT	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
SRR25158348_k127_611729_2	1396141.BATP01000002_gene4802	3.735e-156	499.0	COG0387@1|root,COG0387@2|Bacteria,46UPT@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
SRR25158348_k127_611729_7	492774.JQMB01000013_gene2991	1.838e-36	147.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,4BCYP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158348_k127_611729_11	1125973.JNLC01000001_gene186	2.355e-11	73.0	COG2067@1|root,COG2067@2|Bacteria,1RF1Y@1224|Proteobacteria,2U8A3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SRR25158348_k127_611729_9	95619.PM1_0223610	1.296e-27	119.0	COG2928@1|root,COG2928@2|Bacteria,1NF4R@1224|Proteobacteria,1SFUD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SRR25158348_k127_611729_8	765952.PUV_21530	8.752e-31	124.0	COG1262@1|root,COG1262@2|Bacteria,2JGPQ@204428|Chlamydiae	204428|Chlamydiae	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158348_k127_612728_0	1392501.JIAC01000001_gene798	2.269e-111	370.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H2N9@909932|Negativicutes	909932|Negativicutes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158348_k127_612728_1	765913.ThidrDRAFT_0007	1.029e-28	119.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1WZI2@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_615408_0	243233.MCA1459	8.469e-83	284.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XDTH@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158348_k127_615408_2	1499967.BAYZ01000157_gene585	9.314e-60	211.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
SRR25158348_k127_615408_1	1047013.AQSP01000134_gene1378	2.042e-82	282.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158348_k127_615408_3	1342301.JASD01000008_gene1302	1.143e-08	63.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,3ZV72@60136|Sulfitobacter	28211|Alphaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158348_k127_619855_1	1379698.RBG1_1C00001G0011	6.21e-45	183.0	COG2010@1|root,COG2180@1|root,COG2010@2|Bacteria,COG2180@2|Bacteria,2NR8D@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K00405,ko:K17052	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko02000	3.D.4.3,5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
SRR25158348_k127_619855_0	240015.ACP_0820	2.375e-130	435.0	COG1022@1|root,COG1022@2|Bacteria,3Y2KU@57723|Acidobacteria,2JHTA@204432|Acidobacteriia	204432|Acidobacteriia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158348_k127_620381_0	1123228.AUIH01000092_gene552	2.073e-24	119.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_620381_1	365046.Rta_13040	3.693e-08	64.0	COG3291@1|root,COG3291@2|Bacteria,1RA9Y@1224|Proteobacteria	1224|Proteobacteria	DZ	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR25158348_k127_620520_0	1521187.JPIM01000050_gene3431	7.651e-146	481.0	COG3975@1|root,COG3975@2|Bacteria,2GAB7@200795|Chloroflexi,374W2@32061|Chloroflexia	32061|Chloroflexia	S	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158348_k127_621398_2	1379698.RBG1_1C00001G1798	1.752e-37	145.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_621398_0	795666.MW7_1939	5.648e-59	219.0	COG1633@1|root,COG1633@2|Bacteria,1RB01@1224|Proteobacteria,2VQJI@28216|Betaproteobacteria,1K7GH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158348_k127_621398_1	69042.WH5701_07101	6.007e-51	184.0	COG3408@1|root,COG3408@2|Bacteria,1G2J4@1117|Cyanobacteria,1H00K@1129|Synechococcus	1117|Cyanobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158348_k127_624254_0	595460.RRSWK_03471	3.288e-22	113.0	COG1657@1|root,COG1657@2|Bacteria,2J1Q5@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_624621_0	1340493.JNIF01000003_gene4471	2.341e-87	305.0	COG2304@1|root,COG2304@2|Bacteria,3Y5S3@57723|Acidobacteria	57723|Acidobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SRR25158348_k127_626740_0	1042156.CXIVA_05200	1.003e-49	183.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,36E3E@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
SRR25158348_k127_626740_1	290397.Adeh_3966	4.911e-05	54.0	COG1413@1|root,COG1413@2|Bacteria,1QAUN@1224|Proteobacteria,435B4@68525|delta/epsilon subdivisions,2WZNB@28221|Deltaproteobacteria,2Z2F0@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158348_k127_627512_0	706587.Desti_1725	3.689e-23	99.0	COG0225@1|root,COG0225@2|Bacteria,1N2DQ@1224|Proteobacteria,42UC3@68525|delta/epsilon subdivisions,2WQBZ@28221|Deltaproteobacteria,2MS4Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158348_k127_627512_1	497964.CfE428DRAFT_0055	1.215e-05	53.0	COG0848@1|root,COG0848@2|Bacteria,46W26@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
SRR25158348_k127_628_6	1266908.AQPB01000043_gene1432	1.121e-10	70.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXTV@135613|Chromatiales	135613|Chromatiales	NU	Secretion system protein	-	-	-	ko:K12276	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	T2SSE,T2SSE_N
SRR25158348_k127_628_2	247490.KSU1_C1537	8.399e-69	252.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158348_k127_628_4	1254432.SCE1572_31220	5.26e-44	169.0	COG1028@1|root,COG1028@2|Bacteria	1254432.SCE1572_31220|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158348_k127_628_1	338966.Ppro_2242	4.773e-126	418.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43TE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158348_k127_628_0	760568.Desku_0441	1.787e-270	857.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,260HP@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158348_k127_628_5	237368.SCABRO_00007	1.181e-20	97.0	COG0399@1|root,COG0399@2|Bacteria,2J1H7@203682|Planctomycetes	203682|Planctomycetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_628_3	575540.Isop_0897	8.893e-55	204.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158348_k127_628125_0	1539298.JO41_10020	1.158e-288	900.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2J5JP@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158348_k127_628125_1	439235.Dalk_0093	3.322e-16	85.0	COG0457@1|root,COG0457@2|Bacteria,1R08P@1224|Proteobacteria,43CRB@68525|delta/epsilon subdivisions,2X7YX@28221|Deltaproteobacteria,2MPTV@213118|Desulfobacterales	439235.Dalk_0093|-	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_628163_1	1499967.BAYZ01000084_gene3995	2.198e-54	209.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158348_k127_628163_0	237368.SCABRO_03695	3.821e-80	280.0	COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158348_k127_630098_2	204669.Acid345_3648	2.079e-62	230.0	COG2102@1|root,COG2102@2|Bacteria,3Y46Z@57723|Acidobacteria,2JIS5@204432|Acidobacteriia	204432|Acidobacteriia	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
SRR25158348_k127_630098_0	555088.DealDRAFT_2890	3.141e-70	251.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,42JXY@68298|Syntrophomonadaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158348_k127_630098_3	693661.Arcve_1004	2.297e-38	158.0	COG0614@1|root,arCOG04233@2157|Archaea,2XUJY@28890|Euryarchaeota,246N2@183980|Archaeoglobi	183980|Archaeoglobi	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158348_k127_630098_1	1041930.Mtc_1719	6.748e-64	231.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,2NA71@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158348_k127_630098_4	1532557.JL37_13820	2.985e-19	97.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,2WGMC@28216|Betaproteobacteria,3T62C@506|Alcaligenaceae	28216|Betaproteobacteria	P	Outer membrane receptor proteins mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158348_k127_634085_2	247490.KSU1_C0412	9.221e-43	162.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158348_k127_634085_1	330214.NIDE3421	1.124e-53	202.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
SRR25158348_k127_634085_4	344747.PM8797T_00177	4.365e-25	117.0	2ESRG@1|root,33K9V@2|Bacteria,2J33K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_634085_0	1379698.RBG1_1C00001G1241	9.365e-69	246.0	COG0613@1|root,COG0613@2|Bacteria,2NPWD@2323|unclassified Bacteria	2|Bacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158348_k127_634085_5	552811.Dehly_1438	1.689e-20	95.0	2DNS7@1|root,32YWC@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158348_k127_634085_3	1120936.KB907210_gene5836	5.761e-33	130.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4EGVD@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158348_k127_639037_0	247490.KSU1_C0404	4.871e-22	112.0	COG1333@1|root,COG1333@2|Bacteria,2J0U6@203682|Planctomycetes	203682|Planctomycetes	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
SRR25158348_k127_639037_1	525898.Sdel_0480	0.000812	51.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
SRR25158348_k127_640847_2	1122917.KB899660_gene1789	1.822e-35	136.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,26RCN@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRR25158348_k127_640847_3	237368.SCABRO_00432	8.31e-35	142.0	COG0613@1|root,COG0781@1|root,COG0613@2|Bacteria,COG0781@2|Bacteria,2J058@203682|Planctomycetes	203682|Planctomycetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB,PHP
SRR25158348_k127_640847_0	247490.KSU1_C0960	1.125e-105	351.0	COG0552@1|root,COG0552@2|Bacteria,2IXAG@203682|Planctomycetes	203682|Planctomycetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158348_k127_640847_1	314230.DSM3645_15960	4.765e-58	218.0	COG2231@1|root,COG2231@2|Bacteria,2IZ9A@203682|Planctomycetes	203682|Planctomycetes	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158348_k127_640847_4	215803.DB30_3909	5.891e-22	98.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria,2Z1Q1@29|Myxococcales	28221|Deltaproteobacteria	K	Cold-shock protein	cspE	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158348_k127_640847_6	28444.JODQ01000012_gene3420	4.297e-06	57.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_42M
SRR25158348_k127_640847_5	521045.Kole_0482	9.916e-07	59.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SH3_3
SRR25158348_k127_643335_0	1304885.AUEY01000002_gene357	1.944e-80	277.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MJ5Q@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
SRR25158348_k127_643890_1	330214.NIDE1294	5.376e-58	203.0	COG0050@1|root,COG0050@2|Bacteria,3J0DG@40117|Nitrospirae	40117|Nitrospirae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158348_k127_643890_4	1454004.AW11_03353	1.885e-07	63.0	COG0515@1|root,COG0515@2|Bacteria,1RAG3@1224|Proteobacteria,2W0C1@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
SRR25158348_k127_643890_2	481448.Minf_0344	7.527e-51	206.0	COG1216@1|root,COG1216@2|Bacteria,46VS1@74201|Verrucomicrobia,37G6R@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158348_k127_643890_0	96561.Dole_1678	1.291e-63	241.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,1MUB8@1224|Proteobacteria,42NWQ@68525|delta/epsilon subdivisions,2WM5R@28221|Deltaproteobacteria,2MJ8Y@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,PAS,PAS_4
SRR25158348_k127_644484_0	1242864.D187_006584	1.373e-47	186.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria	1224|Proteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158348_k127_644484_2	101028.EKJ74887	6.526e-11	69.0	2F74C@1|root,2T876@2759|Eukaryota,38S9P@33154|Opisthokonta,3PU15@4751|Fungi,3RDCF@4890|Ascomycota,21J6A@147550|Sordariomycetes,3TPNU@5125|Hypocreales,1FWNU@110618|Nectriaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_644484_1	264462.Bd1337	3.877e-30	122.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
SRR25158348_k127_64550_0	552811.Dehly_1312	3.433e-288	901.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi,34CVH@301297|Dehalococcoidia	2|Bacteria	O	Belongs to the ClpA ClpB family	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158348_k127_64550_5	1121472.AQWN01000012_gene933	4.896e-33	141.0	COG2337@1|root,COG2337@2|Bacteria,1VBXM@1239|Firmicutes,24M9K@186801|Clostridia,262K2@186807|Peptococcaceae	186801|Clostridia	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158348_k127_64550_8	1489678.RDMS_03900	7.479e-19	91.0	COG2336@1|root,COG2336@2|Bacteria,1WN5N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
SRR25158348_k127_64550_9	984262.SGRA_2270	3.129e-10	67.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	MA20_21840	-	3.2.1.96,3.5.1.28	ko:K01227,ko:K01448,ko:K03791,ko:K13277,ko:K17733	ko00511,ko01503,ko02024,map00511,map01503,map02024	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	GH19	-	Amidase_3,DUF1036,Glucosaminidase,PG_binding_1,SH3_3
SRR25158348_k127_64550_4	1267535.KB906767_gene4113	6.176e-38	156.0	COG2940@1|root,COG2940@2|Bacteria,3Y7R1@57723|Acidobacteria	57723|Acidobacteria	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158348_k127_64550_7	886293.Sinac_2129	1.372e-19	96.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,PG_binding_1
SRR25158348_k127_64550_6	926560.KE387023_gene3374	8.313e-31	132.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158348_k127_64550_1	243231.GSU2489	3.73e-68	239.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43TZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Radical SAM domain protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
SRR25158348_k127_64550_2	357808.RoseRS_2395	1.192e-67	259.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158348_k127_64550_3	886293.Sinac_5309	7.844e-53	203.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2J4YP@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158348_k127_646732_0	756272.Plabr_0460	1.682e-61	226.0	COG0515@1|root,COG0515@2|Bacteria,2IXXT@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158348_k127_647890_3	1304275.C41B8_15570	1.605e-23	109.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158348_k127_647890_4	742821.HMPREF9464_00460	3.328e-21	101.0	COG0515@1|root,COG0515@2|Bacteria,1N75K@1224|Proteobacteria,2W05P@28216|Betaproteobacteria,4PQYC@995019|Sutterellaceae	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_647890_1	621372.ACIH01000145_gene128	4.745e-67	245.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,26QFI@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SRR25158348_k127_647890_0	32057.KB217483_gene9483	2.035e-103	345.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria,1HQRD@1161|Nostocales	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_647890_2	118166.JH976537_gene4868	4.839e-53	190.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1H7AV@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158348_k127_648028_0	1267534.KB906755_gene4691	1.399e-64	243.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_648028_1	1267533.KB906733_gene2989	5.015e-43	171.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158348_k127_654249_1	1429916.X566_21020	2.547e-70	246.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158348_k127_654249_2	1429916.X566_21020	3.182e-69	252.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158348_k127_654249_0	748280.NH8B_2766	4.839e-123	401.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158348_k127_658324_1	309799.DICTH_1698	1.452e-32	131.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158348_k127_658324_0	671143.DAMO_0012	6.702e-216	684.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158348_k127_658324_2	1268237.G114_01769	6.122e-21	100.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1Y48V@135624|Aeromonadales	135624|Aeromonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_661693_0	290397.Adeh_2455	5.782e-93	319.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158348_k127_661693_1	944480.ATUV01000002_gene251	1.521e-72	253.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,42P3H@68525|delta/epsilon subdivisions,2WK0J@28221|Deltaproteobacteria,2M7JI@213113|Desulfurellales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_663103_0	1038859.AXAU01000016_gene6869	2.973e-138	445.0	COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158348_k127_664073_2	639282.DEFDS_0125	2.423e-16	92.0	COG2176@1|root,COG2176@2|Bacteria,2GFKN@200930|Deferribacteres	200930|Deferribacteres	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158348_k127_664073_0	1068980.ARVW01000001_gene5449	1.564e-45	175.0	COG1028@1|root,COG1028@2|Bacteria,2H8Y7@201174|Actinobacteria,4E21V@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158348_k127_664073_1	269797.Mbar_A0134	2.962e-30	124.0	COG0720@1|root,arCOG02172@2157|Archaea,2XZ5K@28890|Euryarchaeota,2N9WF@224756|Methanomicrobia	224756|Methanomicrobia	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158348_k127_666009_3	374847.Kcr_1238	4.856e-09	58.0	COG1694@1|root,arCOG01084@2157|Archaea	2157|Archaea	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG,MazG-like
SRR25158348_k127_666009_2	32042.PstZobell_13361	2.805e-10	74.0	2983E@1|root,2ZV9D@2|Bacteria,1QTCK@1224|Proteobacteria,1SV2J@1236|Gammaproteobacteria,1Z3GX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_666009_1	234267.Acid_0586	2.727e-43	182.0	COG5373@1|root,COG5373@2|Bacteria,3Y44X@57723|Acidobacteria	57723|Acidobacteria	NU	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158348_k127_666009_0	234267.Acid_0588	3.525e-103	346.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158348_k127_672783_1	880072.Desac_0568	1.323e-31	129.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MR53@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158348_k127_672783_2	521045.Kole_1369	5.242e-31	126.0	COG0346@1|root,COG0346@2|Bacteria,2GD4G@200918|Thermotogae	200918|Thermotogae	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158348_k127_672783_3	595460.RRSWK_01783	5.558e-25	106.0	COG0236@1|root,COG0236@2|Bacteria,2J0V5@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158348_k127_672783_0	243090.RB320	1.971e-153	497.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158348_k127_672783_4	575540.Isop_2719	3.362e-19	88.0	COG4956@1|root,COG4956@2|Bacteria,2IXF3@203682|Planctomycetes	203682|Planctomycetes	S	Integral membrane protein (PIN domain superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4,TRAM
SRR25158348_k127_673609_0	1230342.CTM_20946	3.164e-30	136.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,36FR1@31979|Clostridiaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_4,Big_5,CW_binding_2,SH3_3
SRR25158348_k127_673609_2	78245.Xaut_0919	3.895e-05	53.0	COG1413@1|root,COG1413@2|Bacteria,1RJJI@1224|Proteobacteria,2UH57@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_673609_1	760568.Desku_1421	1.096e-11	68.0	COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,261U3@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
SRR25158348_k127_673837_1	1125863.JAFN01000001_gene1391	4.216e-24	111.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
SRR25158348_k127_673837_0	886293.Sinac_1412	2.065e-46	182.0	COG1355@1|root,COG1355@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR25158348_k127_676133_0	378806.STAUR_3251	1.502e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,1QX7S@1224|Proteobacteria,43C0S@68525|delta/epsilon subdivisions,2X7BD@28221|Deltaproteobacteria,2YV1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_676133_1	596151.DesfrDRAFT_3754	2.366e-05	57.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,1NDC7@1224|Proteobacteria,42V4C@68525|delta/epsilon subdivisions,2WRS8@28221|Deltaproteobacteria,2M89T@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,STAS,STAS_2
SRR25158348_k127_680436_0	1173021.ALWA01000010_gene1449	1.109e-53	206.0	COG4191@1|root,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4
SRR25158348_k127_682646_2	1125863.JAFN01000001_gene1785	2.08e-62	234.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
SRR25158348_k127_682646_1	123214.PERMA_1131	1.199e-92	312.0	COG1951@1|root,COG1951@2|Bacteria,2G3JI@200783|Aquificae	200783|Aquificae	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
SRR25158348_k127_682646_0	1123508.JH636441_gene3158	1.125e-95	321.0	COG1131@1|root,COG1131@2|Bacteria,2IZ31@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_683444_1	477974.Daud_2020	4.667e-39	168.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,2606M@186807|Peptococcaceae	186801|Clostridia	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_683444_2	502025.Hoch_6762	5.243e-13	83.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,42ND4@68525|delta/epsilon subdivisions,2WKQP@28221|Deltaproteobacteria,2YUMU@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_683444_0	575540.Isop_1258	1.632e-94	323.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158348_k127_684209_2	1156937.MFUM_230017	1.355e-20	96.0	COG0629@1|root,COG0629@2|Bacteria,46VWS@74201|Verrucomicrobia,37GQJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158348_k127_684209_0	635013.TherJR_0131	2.859e-112	379.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
SRR25158348_k127_684209_1	247490.KSU1_B0544	1.099e-73	270.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	203682|Planctomycetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158348_k127_684521_2	1144275.COCOR_07430	5.238e-39	156.0	COG2802@1|root,COG2802@2|Bacteria,1Q90Z@1224|Proteobacteria,43426@68525|delta/epsilon subdivisions,2X4S2@28221|Deltaproteobacteria,2YVIH@29|Myxococcales	28221|Deltaproteobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158348_k127_684521_0	370438.PTH_0827	2.256e-176	574.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,260PP@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158348_k127_684521_1	118163.Ple7327_1903	1.511e-106	354.0	COG0492@1|root,COG3118@1|root,COG0492@2|Bacteria,COG3118@2|Bacteria,1G15I@1117|Cyanobacteria,3VINA@52604|Pleurocapsales	1117|Cyanobacteria	O	TIGRFAM thioredoxin-disulfide reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
SRR25158348_k127_684521_3	1123261.AXDW01000024_gene2070	1.603e-21	101.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1X4CK@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_685435_0	1185876.BN8_01058	1.168e-60	228.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SRR25158348_k127_685435_1	1408224.SAMCCGM7_c3469	8.922e-44	169.0	COG0458@1|root,COG0458@2|Bacteria,1RJ88@1224|Proteobacteria,2UB8A@28211|Alphaproteobacteria,4BGH6@82115|Rhizobiaceae	28211|Alphaproteobacteria	EF	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
SRR25158348_k127_685663_0	484770.UFO1_1464	1.052e-46	181.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4H723@909932|Negativicutes	909932|Negativicutes	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158348_k127_685663_2	269799.Gmet_1439	2.843e-35	141.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42URP@68525|delta/epsilon subdivisions,2WQFZ@28221|Deltaproteobacteria,43UTN@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158348_k127_685663_1	1173024.KI912149_gene5660	2.755e-46	170.0	COG0614@1|root,COG0614@2|Bacteria,1G71C@1117|Cyanobacteria	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
SRR25158348_k127_685663_4	247490.KSU1_C0242	0.0005285	46.0	2EJQV@1|root,33DFP@2|Bacteria,2J3W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_685663_3	207559.Dde_3621	6.721e-30	123.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2M80Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158348_k127_685738_0	457570.Nther_2188	9.271e-100	345.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158348_k127_686361_0	886293.Sinac_6281	3.706e-270	874.0	COG1196@1|root,COG1674@1|root,COG1196@2|Bacteria,COG1674@2|Bacteria,2IXPG@203682|Planctomycetes	203682|Planctomycetes	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR25158348_k127_686361_1	324602.Caur_0925	4.402e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_688105_0	1459636.NTE_01231	1.062e-212	671.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158348_k127_69316_1	562970.Btus_3314	1.516e-59	215.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,27886@186823|Alicyclobacillaceae	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
SRR25158348_k127_69316_0	1267534.KB906755_gene4317	8.956e-68	236.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria,2JI6M@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158348_k127_69316_2	575540.Isop_1410	1.857e-39	149.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2IWW1@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158348_k127_697216_0	1071073.KI530544_gene2887	2.612e-33	135.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,4HAX3@91061|Bacilli,1ZG4E@1386|Bacillus	91061|Bacilli	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_697216_1	1173028.ANKO01000056_gene2183	1.169e-22	106.0	28MBR@1|root,2ZAQ6@2|Bacteria,1G1NF@1117|Cyanobacteria,1HB2J@1150|Oscillatoriales	1117|Cyanobacteria	S	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158348_k127_699133_1	1279038.KB907340_gene1594	5.039e-24	109.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2JPN0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158348_k127_699133_0	323261.Noc_0268	3.195e-116	388.0	COG0021@1|root,COG0021@2|Bacteria,1QYA4@1224|Proteobacteria	1224|Proteobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158348_k127_699989_0	485915.Dret_0233	2.292e-72	257.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2M824@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158348_k127_699989_2	1340493.JNIF01000003_gene4475	2.405e-17	88.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158348_k127_699989_1	1219049.SP5_018_00760	1.18e-31	128.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2K5EU@204457|Sphingomonadales	204457|Sphingomonadales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR25158348_k127_702546_3	582515.KR51_00000030	1.165e-06	58.0	COG0457@1|root,COG0457@2|Bacteria	582515.KR51_00000030|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_702546_1	696281.Desru_1167	1.062e-27	120.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158348_k127_702546_0	1121468.AUBR01000032_gene1173	1.373e-53	195.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,42GV6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR25158348_k127_702546_2	768706.Desor_3339	1.625e-16	93.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,261XM@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158348_k127_703029_1	344747.PM8797T_19156	7.393e-18	97.0	COG1340@1|root,COG1450@1|root,COG1340@2|Bacteria,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158348_k127_703029_0	237368.SCABRO_00695	1.516e-48	194.0	COG1450@1|root,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158348_k127_703991_2	903818.KI912269_gene457	8.776e-44	164.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria	57723|Acidobacteria	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158348_k127_703991_1	391625.PPSIR1_15230	3.772e-55	211.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158348_k127_703991_0	247490.KSU1_D0698	1.476e-118	397.0	COG0773@1|root,COG0773@2|Bacteria,2IYEH@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158348_k127_711889_6	1227352.C173_09051	1.729e-12	79.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,4HS5J@91061|Bacilli,26X6Y@186822|Paenibacillaceae	91061|Bacilli	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2,zinc_ribbon_2
SRR25158348_k127_711889_0	867903.ThesuDRAFT_02080	3.129e-126	413.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,25DGF@186801|Clostridia	186801|Clostridia	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158348_k127_711889_3	1267535.KB906767_gene874	1.046e-50	190.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_711889_5	1282876.BAOK01000001_gene960	4.475e-35	146.0	COG1597@1|root,COG1597@2|Bacteria,1RIPU@1224|Proteobacteria,2TVUD@28211|Alphaproteobacteria,4BQTY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158348_k127_711889_1	429009.Adeg_0532	3.684e-118	394.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_711889_4	1232410.KI421424_gene1590	1.665e-42	172.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158348_k127_711889_2	575540.Isop_1087	3.717e-62	219.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158348_k127_713973_1	1504672.669787503	1.61e-43	164.0	COG0304@1|root,COG0304@2|Bacteria,1R618@1224|Proteobacteria,2VW53@28216|Betaproteobacteria,4AK55@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	synthase	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ketoacyl-synt
SRR25158348_k127_713973_2	1504672.669787502	2.508e-40	160.0	COG1196@1|root,COG1196@2|Bacteria,1RJS1@1224|Proteobacteria,2VVCD@28216|Betaproteobacteria,4AHV8@80864|Comamonadaceae	28216|Betaproteobacteria	D	Domain of unknown function (DUF4150)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150
SRR25158348_k127_713973_3	208444.JNYY01000001_gene5158	2.05e-20	102.0	2APEP@1|root,31EHC@2|Bacteria,2H5GN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_713973_0	330214.NIDE2002	4.015e-81	295.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158348_k127_719843_1	886293.Sinac_1051	2.234e-62	239.0	COG0515@1|root,COG0515@2|Bacteria,2IY6U@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158348_k127_719843_0	1123508.JH636439_gene979	6.168e-72	258.0	COG5492@1|root,COG5492@2|Bacteria,2J1RI@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
SRR25158348_k127_723010_0	1304888.ATWF01000001_gene2311	1.903e-10	61.0	COG0653@1|root,COG0653@2|Bacteria,2GEMD@200930|Deferribacteres	200930|Deferribacteres	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158348_k127_724146_0	429009.Adeg_1311	2.173e-53	214.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158348_k127_731484_1	309807.SRU_1796	7.463e-44	168.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1FITK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158348_k127_731484_0	1379270.AUXF01000005_gene720	8.784e-75	271.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158348_k127_733858_0	748449.Halha_0522	0.0006113	50.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes	1239|Firmicutes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158348_k127_735052_1	575540.Isop_1258	7.165e-10	60.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158348_k127_735052_0	1121020.JIAG01000001_gene1061	2.582e-23	112.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,1W8Q4@1268|Micrococcaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_735052_2	221109.22776140	1.207e-05	57.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,4H9VP@91061|Bacilli,23J7X@182709|Oceanobacillus	91061|Bacilli	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158348_k127_741594_2	1121447.JONL01000004_gene2910	2.048e-07	57.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,2MB8V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF2345,Phage_GPD,T6SS_Vgr
SRR25158348_k127_741594_0	1097668.BYI23_C001930	2.458e-309	971.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,2VHSN@28216|Betaproteobacteria,1K184@119060|Burkholderiaceae	28216|Betaproteobacteria	O	type VI secretion ATPase, ClpV1 family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158348_k127_741594_1	1192034.CAP_5556	3.141e-57	211.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,42Q2Y@68525|delta/epsilon subdivisions,2X3B8@28221|Deltaproteobacteria,2YV7T@29|Myxococcales	28221|Deltaproteobacteria	S	Type VI secretion, TssG	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
SRR25158348_k127_742081_1	1232410.KI421428_gene1166	1.315e-65	227.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2WMSC@28221|Deltaproteobacteria,43SFW@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Proteasome subunit	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158348_k127_742081_0	1232410.KI421428_gene1165	2.53e-129	430.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,43S1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158348_k127_745700_3	338966.Ppro_0408	7.819e-10	62.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_745700_1	864051.BurJ1DRAFT_3859	5.982e-47	188.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_745700_0	1297742.A176_02305	6.06e-60	215.0	COG1502@1|root,COG1502@2|Bacteria,1RG9Z@1224|Proteobacteria,42RRF@68525|delta/epsilon subdivisions,2X6P0@28221|Deltaproteobacteria,2YXQC@29|Myxococcales	28221|Deltaproteobacteria	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158348_k127_745700_2	1121373.KB903629_gene354	2.912e-13	76.0	COG2770@1|root,COG2770@2|Bacteria,4NPRN@976|Bacteroidetes	976|Bacteroidetes	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
SRR25158348_k127_747373_1	1121286.AUMT01000002_gene1407	4.239e-06	55.0	COG3021@1|root,COG3021@2|Bacteria,4PKDH@976|Bacteroidetes,1HYUN@117743|Flavobacteriia,3ZPSS@59732|Chryseobacterium	976|Bacteroidetes	S	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158348_k127_747373_0	404589.Anae109_0210	1.391e-66	238.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,2Z2XX@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158348_k127_74766_1	661478.OP10G_0324	1.381e-10	62.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158348_k127_74766_0	926560.KE387023_gene2049	1.7e-114	389.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRR25158348_k127_753535_0	404589.Anae109_2693	1.386e-202	653.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158348_k127_753535_1	1120973.AQXL01000129_gene2454	1.936e-54	199.0	COG0132@1|root,COG0132@2|Bacteria,1V4DE@1239|Firmicutes,4HID2@91061|Bacilli,278E2@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR25158348_k127_753535_2	661478.OP10G_1178	1.811e-18	95.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
SRR25158348_k127_756017_0	1379698.RBG1_1C00001G0615	7.452e-116	385.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158348_k127_756017_1	340.xcc-b100_4421	5.18e-09	70.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1SG73@1236|Gammaproteobacteria,1X5NU@135614|Xanthomonadales	135614|Xanthomonadales	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,He_PIG
SRR25158348_k127_75887_1	443143.GM18_3743	1.394e-81	280.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,43TGQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158348_k127_75887_0	880072.Desac_1519	3.57e-118	392.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2MR01@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158348_k127_761494_0	1111479.AXAR01000014_gene1192	8.342e-235	744.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,2781C@186823|Alicyclobacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158348_k127_767465_6	390874.Tpet_0090	0.0008324	47.0	COG2804@1|root,COG2804@2|Bacteria,2GCDW@200918|Thermotogae	200918|Thermotogae	NU	PFAM type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158348_k127_767465_2	1123242.JH636435_gene1165	1.017e-42	181.0	COG0515@1|root,COG0515@2|Bacteria,2IZIG@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158348_k127_767465_1	926550.CLDAP_27410	2.811e-69	257.0	COG1131@1|root,COG1131@2|Bacteria,2G6KA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_767465_4	1122611.KB903983_gene3512	3.644e-11	77.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria,4EI44@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158348_k127_767465_0	1521187.JPIM01000050_gene3431	1.979e-79	287.0	COG3975@1|root,COG3975@2|Bacteria,2GAB7@200795|Chloroflexi,374W2@32061|Chloroflexia	32061|Chloroflexia	S	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
SRR25158348_k127_767465_5	52644.XP_010564520.1	3.64e-05	55.0	COG0457@1|root,KOG1124@2759|Eukaryota,38F8U@33154|Opisthokonta,3BAQE@33208|Metazoa,3CV5D@33213|Bilateria,4828P@7711|Chordata,4912M@7742|Vertebrata,4GRW1@8782|Aves	33208|Metazoa	S	Transmembrane and TPR repeat-containing protein 1	TMTC1	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
SRR25158348_k127_767465_3	1206739.BAGJ01000037_gene2678	7.647e-22	106.0	COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,4FVEP@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4352,Pkinase,TPR_10
SRR25158348_k127_771662_0	269799.Gmet_0961	1.537e-96	332.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158348_k127_771662_1	1235457.C404_21235	2.999e-87	301.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
SRR25158348_k127_771662_4	1218076.BAYB01000015_gene3180	1.215e-06	54.0	COG0640@1|root,COG0640@2|Bacteria,1N8M7@1224|Proteobacteria,2VYT5@28216|Betaproteobacteria,1K8BB@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158348_k127_771662_2	429009.Adeg_1759	3.025e-29	134.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158348_k127_771662_3	28072.Nos7524_3942	3.103e-08	64.0	COG1413@1|root,COG1413@2|Bacteria,1G0N6@1117|Cyanobacteria,1HKMR@1161|Nostocales	1117|Cyanobacteria	C	PFAM PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158348_k127_773616_2	243365.CV_3176	8.451e-30	125.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2VM2U@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
SRR25158348_k127_773616_3	945713.IALB_1953	2.182e-23	108.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158348_k127_773616_0	1297742.A176_00627	0.0	1030.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158348_k127_773616_1	1278073.MYSTI_03986	5.229e-55	209.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WN4R@28221|Deltaproteobacteria,2YVY4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158348_k127_773616_4	107636.JQNK01000009_gene1638	7.623e-14	83.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,36XKM@31993|Methylocystaceae	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158348_k127_773751_9	1123376.AUIU01000003_gene1639	1.563e-20	100.0	COG4974@1|root,COG4974@2|Bacteria,3J1FQ@40117|Nitrospirae	40117|Nitrospirae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158348_k127_773751_0	402881.Plav_0385	2.335e-221	706.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,1JN5A@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158348_k127_773751_4	1121106.JQKB01000049_gene3069	1.033e-46	175.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_773751_1	1122185.N792_00885	3.687e-63	238.0	COG0793@1|root,COG0793@2|Bacteria,1NK7B@1224|Proteobacteria,1SIMC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158348_k127_773751_7	756272.Plabr_4031	5.926e-23	114.0	COG1680@1|root,COG1680@2|Bacteria,2IZDA@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158348_k127_773751_3	1502852.FG94_00959	3.903e-50	184.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,4742C@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158348_k127_773751_2	314230.DSM3645_07370	1.127e-61	221.0	295WE@1|root,2ZT7B@2|Bacteria,2J2RS@203682|Planctomycetes	203682|Planctomycetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
SRR25158348_k127_773751_11	269798.CHU_3112	3.003e-08	63.0	2DS4P@1|root,33EH8@2|Bacteria,4PPZ4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_773751_5	661478.OP10G_3568	2.276e-34	142.0	295WE@1|root,2ZT7B@2|Bacteria	2|Bacteria	S	Membrane bound O-acyl transferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT_2
SRR25158348_k127_773751_8	797114.C475_09434	1.346e-22	112.0	arCOG11971@1|root,arCOG11971@2157|Archaea,2XWIZ@28890|Euryarchaeota,23VA2@183963|Halobacteria	183963|Halobacteria	S	YndJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YndJ
SRR25158348_k127_773751_10	1460640.JCM19046_2841	4.047e-13	82.0	29RNN@1|root,30CRY@2|Bacteria,1UP6P@1239|Firmicutes,4HBII@91061|Bacilli,1ZF3C@1386|Bacillus	91061|Bacilli	S	DoxX-like family	yndG	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
SRR25158348_k127_773751_6	1121373.KB903643_gene3447	5.981e-31	132.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158348_k127_774341_0	338966.Ppro_2406	1.879e-105	358.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43TW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158348_k127_774341_1	562983.HMPREF0433_01610	2.088e-07	55.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4I6J7@91061|Bacilli,3WF43@539002|Bacillales incertae sedis	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	-	-	-	-	-	-	-	-	-	-	Exonuc_VII_S
SRR25158348_k127_774764_0	204669.Acid345_1930	4.831e-246	774.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria,2JKA8@204432|Acidobacteriia	204432|Acidobacteriia	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158348_k127_774764_1	379066.GAU_0543	1.974e-74	264.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158348_k127_77502_0	926550.CLDAP_07150	2.618e-174	556.0	COG4263@1|root,COG4263@2|Bacteria,2G8B2@200795|Chloroflexi	200795|Chloroflexi	C	nitrous-oxide reductase activity	-	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158348_k127_77502_2	518766.Rmar_2013	5.881e-34	138.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1FJJY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
SRR25158348_k127_77502_1	518766.Rmar_2014	6.251e-39	167.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1FJC4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Domain present in carbohydrate binding proteins and sugar hydrolses	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
SRR25158348_k127_775918_1	344747.PM8797T_29952	2.304e-55	207.0	COG2373@1|root,COG2373@2|Bacteria,2IYJD@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
SRR25158348_k127_775918_2	1307759.JOMJ01000003_gene801	6.385e-52	195.0	COG0438@1|root,COG0438@2|Bacteria,1R3TV@1224|Proteobacteria,42SVW@68525|delta/epsilon subdivisions,2WPMR@28221|Deltaproteobacteria,2MAH1@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4
SRR25158348_k127_775918_0	1210884.HG799462_gene8785	1.191e-58	209.0	COG0693@1|root,COG0693@2|Bacteria,2IYYE@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158348_k127_775918_3	575540.Isop_1296	2.683e-43	177.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,PSCyt2,PSD1
SRR25158348_k127_777358_1	688269.Theth_0659	1.731e-37	151.0	COG1670@1|root,COG1670@2|Bacteria,2GCZ2@200918|Thermotogae	200918|Thermotogae	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
SRR25158348_k127_777358_0	652103.Rpdx1_1792	2.12e-93	310.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria,3K275@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158348_k127_778250_2	1121479.AUBS01000007_gene2221	9.368e-40	152.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158348_k127_778250_0	247490.KSU1_C1241	1.767e-220	700.0	COG1217@1|root,COG1217@2|Bacteria,2IY3Q@203682|Planctomycetes	203682|Planctomycetes	T	membrane GTPase involved in stress response	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158348_k127_778250_1	1167006.UWK_00579	2.111e-151	487.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N31@68525|delta/epsilon subdivisions,2X6FB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158348_k127_779506_1	521674.Plim_1811	1.453e-29	130.0	COG0265@1|root,COG0265@2|Bacteria,2IY6F@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_779506_0	314230.DSM3645_24912	1.272e-44	175.0	COG0265@1|root,COG0265@2|Bacteria,2IXA0@203682|Planctomycetes	203682|Planctomycetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_781584_1	756272.Plabr_4682	3.387e-23	106.0	COG0265@1|root,COG0265@2|Bacteria,2IY6F@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_781584_0	644282.Deba_0724	5.656e-45	185.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_781682_0	247490.KSU1_C0739	6.526e-120	406.0	COG1074@1|root,COG1074@2|Bacteria,2IX2I@203682|Planctomycetes	203682|Planctomycetes	L	UvrD REP helicase	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158348_k127_781682_1	1157490.EL26_13260	1.56e-11	71.0	COG3857@1|root,COG3857@2|Bacteria,1TVKS@1239|Firmicutes,4I3G1@91061|Bacilli,278HN@186823|Alicyclobacillaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158348_k127_783956_1	648757.Rvan_0617	3.062e-66	232.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,3N6IM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158348_k127_783956_2	316067.Geob_2384	5.288e-39	163.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43T0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158348_k127_783956_3	1254432.SCE1572_21210	2.465e-16	88.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_783956_0	1123508.JH636439_gene1080	3.469e-68	259.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
SRR25158348_k127_78857_3	34007.IT40_24760	1.485e-11	65.0	COG2044@1|root,COG2044@2|Bacteria,1RIFN@1224|Proteobacteria,2UBMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158348_k127_78857_2	1123507.ATVQ01000003_gene618	3.796e-17	89.0	2BMJ7@1|root,32G45@2|Bacteria,2H1DR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158348_k127_78857_1	883113.HMPREF9708_01265	2.934e-37	159.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,4HRIU@91061|Bacilli	91061|Bacilli	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158348_k127_78857_0	290317.Cpha266_0557	4.647e-44	173.0	COG3074@1|root,COG3074@2|Bacteria,1FFHR@1090|Chlorobi	1090|Chlorobi	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_788635_0	927677.ALVU02000001_gene1324	2.527e-22	112.0	COG3225@1|root,COG3225@2|Bacteria,1G0JN@1117|Cyanobacteria,1H56R@1142|Synechocystis	1117|Cyanobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
SRR25158348_k127_788635_1	1499967.BAYZ01000095_gene4169	4.567e-05	47.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
SRR25158348_k127_789064_0	521674.Plim_0772	7.457e-52	192.0	COG0167@1|root,COG0167@2|Bacteria,2IX71@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.1,1.3.1.14	ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158348_k127_789064_2	247490.KSU1_D0650	2.322e-21	102.0	COG0597@1|root,COG0597@2|Bacteria,2J0RI@203682|Planctomycetes	203682|Planctomycetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158348_k127_789064_1	237368.SCABRO_03449	7.107e-25	113.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158348_k127_789064_3	1504822.CCNO01000011_gene137	0.0003164	47.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158348_k127_793501_1	439235.Dalk_0845	4.025e-107	352.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MKSR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
SRR25158348_k127_793501_0	247490.KSU1_D0083	8.115e-124	403.0	COG0451@1|root,COG0451@2|Bacteria,2IYBF@203682|Planctomycetes	203682|Planctomycetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158348_k127_794395_1	525909.Afer_0088	1.852e-49	203.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CMUZ@84992|Acidimicrobiia	84992|Acidimicrobiia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158348_k127_794395_2	1123508.JH636440_gene2206	1.216e-37	149.0	COG0764@1|root,COG0764@2|Bacteria,2IZNA@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158348_k127_794395_3	1303518.CCALI_02779	2.217e-10	64.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158348_k127_794395_0	518766.Rmar_0603	3.873e-72	265.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1FJJN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158348_k127_795264_2	314230.DSM3645_09087	1.543e-09	61.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
SRR25158348_k127_795264_1	1121472.AQWN01000008_gene1877	8.662e-15	78.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,2634E@186807|Peptococcaceae	186801|Clostridia	G	TIGRFAM Phosphotransferase System	ptsH	-	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	-	PTS-HPr
SRR25158348_k127_795264_0	247490.KSU1_C0159	6.597e-151	499.0	COG1080@1|root,COG1080@2|Bacteria,2IX08@203682|Planctomycetes	203682|Planctomycetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
SRR25158348_k127_795264_3	761193.Runsl_5309	7.817e-09	64.0	COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia	976|Bacteroidetes	I	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
SRR25158348_k127_799465_0	1123242.JH636435_gene1534	2.851e-75	278.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_799465_2	984892.SPSE_1132	2.395e-67	242.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,4GX33@90964|Staphylococcaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158348_k127_799465_1	247490.KSU1_C1592	4.196e-69	247.0	COG0373@1|root,COG0373@2|Bacteria,2IXE9@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158348_k127_803355_0	706587.Desti_1416	3.081e-82	280.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MQ9Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158348_k127_803355_1	867903.ThesuDRAFT_01636	4.406e-54	213.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158348_k127_803937_1	1280673.AUJJ01000008_gene580	1.15e-28	118.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,4BW26@830|Butyrivibrio	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158348_k127_803937_0	886293.Sinac_2760	6.53e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158348_k127_803937_2	324602.Caur_2958	3.336e-27	119.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158348_k127_805154_2	1121019.AUMN01000042_gene5	1.271e-33	138.0	COG0794@1|root,COG0794@2|Bacteria,2IBB3@201174|Actinobacteria,1WBGA@1268|Micrococcaceae	201174|Actinobacteria	M	SIS domain	rmpB	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
SRR25158348_k127_805154_1	926692.AZYG01000074_gene2438	5.343e-46	178.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3WARH@53433|Halanaerobiales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158348_k127_805154_0	479434.Sthe_0916	5.701e-57	205.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,27Y5G@189775|Thermomicrobia	189775|Thermomicrobia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158348_k127_80806_3	296591.Bpro_2831	3.672e-113	369.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,4ACX8@80864|Comamonadaceae	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158348_k127_80806_4	717605.Theco_1893	1.625e-64	230.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,26QZR@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158348_k127_80806_0	1499967.BAYZ01000170_gene5483	2.235e-152	524.0	COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158348_k127_80806_1	747365.Thena_0728	2.557e-143	470.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,42FFM@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158348_k127_80806_2	247490.KSU1_C1001	5.214e-142	480.0	COG0104@1|root,COG0104@2|Bacteria,2IWZH@203682|Planctomycetes	203682|Planctomycetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158348_k127_80806_5	700598.Niako_0486	1.531e-38	158.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158348_k127_80806_7	1379698.RBG1_1C00001G1399	8.795e-17	94.0	COG4447@1|root,COG4447@2|Bacteria,2NRC1@2323|unclassified Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
SRR25158348_k127_80806_6	700598.Niako_5053	2.294e-24	116.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158348_k127_811812_0	861299.J421_4428	1.591e-131	431.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158348_k127_811812_1	1123322.KB904680_gene3248	4.905e-69	248.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria	201174|Actinobacteria	H	squalene-associated FAD-dependent desaturase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158348_k127_814195_0	105559.Nwat_2708	2.315e-128	437.0	COG3087@1|root,COG3087@2|Bacteria,1QUVJ@1224|Proteobacteria,1RS8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_814195_1	172088.AUGA01000020_gene3638	1.766e-05	55.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3JSJ1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
SRR25158348_k127_819606_1	685035.ADAE01000003_gene2781	2.691e-65	236.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1PTWJ@1224|Proteobacteria,2U237@28211|Alphaproteobacteria,2K176@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,Peptidase_M1
SRR25158348_k127_819606_0	1124780.ANNU01000002_gene1510	1.227e-69	240.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158348_k127_819743_1	1183438.GKIL_3215	7.347e-118	396.0	COG0260@1|root,COG0260@2|Bacteria,1G079@1117|Cyanobacteria	1117|Cyanobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158348_k127_819743_3	204669.Acid345_1475	5.171e-50	194.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158348_k127_819743_0	443143.GM18_3499	1.702e-163	526.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,43U3Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158348_k127_819743_2	269799.Gmet_1653	9.701e-104	341.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,42PJM@68525|delta/epsilon subdivisions,2WKJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158348_k127_827909_1	985665.HPL003_00815	2.187e-47	178.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4HEB4@91061|Bacilli,26Q9J@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_827909_0	1286171.EAL2_808p04300	5.755e-113	376.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,25CRU@186801|Clostridia	186801|Clostridia	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158348_k127_827909_2	297246.lpp1137	2.322e-07	64.0	COG1196@1|root,COG1196@2|Bacteria,1NDEE@1224|Proteobacteria,1SJIB@1236|Gammaproteobacteria,1JDUW@118969|Legionellales	118969|Legionellales	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158348_k127_827950_3	1297742.A176_07378	1.954e-11	67.0	COG2850@1|root,COG2850@2|Bacteria	2|Bacteria	P	peptidyl-arginine hydroxylation	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158348_k127_827950_0	1123508.JH636442_gene3961	1.354e-174	580.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
SRR25158348_k127_827950_2	1163409.UUA_10086	4.056e-36	139.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,1S8TD@1236|Gammaproteobacteria,1X7HX@135614|Xanthomonadales	135614|Xanthomonadales	P	PFAM small multidrug resistance protein	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR25158348_k127_827950_1	886293.Sinac_4912	4.681e-143	462.0	COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes	203682|Planctomycetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158348_k127_828524_0	347834.RHE_CH01027	2.24e-151	489.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2V011@28211|Alphaproteobacteria,4BFYR@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158348_k127_828524_1	316067.Geob_2847	1.128e-06	54.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158348_k127_829095_0	195250.CM001776_gene1981	1.539e-114	383.0	COG0523@1|root,COG0523@2|Bacteria,1G1BG@1117|Cyanobacteria,1H03A@1129|Synechococcus	1117|Cyanobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
SRR25158348_k127_829095_2	1121933.AUHH01000018_gene2849	2.034e-12	71.0	2A1IX@1|root,30PSR@2|Bacteria,2GY0D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_829095_1	204669.Acid345_1339	3.359e-54	199.0	COG2912@1|root,COG2912@2|Bacteria,3Y53Z@57723|Acidobacteria,2JMYF@204432|Acidobacteriia	204432|Acidobacteriia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158348_k127_831162_2	1210884.HG799464_gene10774	5.534e-50	192.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158348_k127_831162_1	794903.OPIT5_09100	1.759e-63	224.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_831162_0	886293.Sinac_4851	7.814e-72	258.0	COG0577@1|root,COG0577@2|Bacteria,2IY8W@203682|Planctomycetes	203682|Planctomycetes	V	Permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158348_k127_832982_0	1382359.JIAL01000001_gene2121	4.817e-17	89.0	COG2318@1|root,COG2318@2|Bacteria,3Y4TP@57723|Acidobacteria,2JJPR@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158348_k127_834294_0	530564.Psta_2559	4.274e-121	393.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158348_k127_834294_3	886293.Sinac_0509	4.721e-05	55.0	COG0267@1|root,COG0267@2|Bacteria,2J1HX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158348_k127_834294_2	247490.KSU1_C1195	1.676e-13	81.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158348_k127_834294_1	756272.Plabr_2011	7.449e-30	123.0	COG0250@1|root,COG0250@2|Bacteria,2IZ9N@203682|Planctomycetes	203682|Planctomycetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158348_k127_836222_2	1134912.AJTV01000002_gene1742	1.734e-93	316.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,36XKP@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Domain of unknown function (DUF1730)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SRR25158348_k127_836222_7	251221.35212953	6.478e-35	139.0	COG1670@1|root,COG1670@2|Bacteria,1G8U5@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158348_k127_836222_6	861299.J421_4225	2.329e-43	171.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
SRR25158348_k127_836222_3	1122182.KB903819_gene125	1.986e-70	246.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158348_k127_836222_10	1129794.C427_3837	6.121e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,467GU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
SRR25158348_k127_836222_12	204669.Acid345_1052	1.147e-05	59.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158348_k127_836222_13	1201290.M902_1734	0.0008502	50.0	2EC0X@1|root,33605@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_836222_11	886293.Sinac_2991	7.272e-06	59.0	2EEQZ@1|root,338IP@2|Bacteria,2J15B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_836222_4	797209.ZOD2009_03075	1.384e-50	197.0	COG1331@1|root,arCOG02007@2157|Archaea,2XT1C@28890|Euryarchaeota,23SUJ@183963|Halobacteria	183963|Halobacteria	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158348_k127_836222_9	903814.ELI_0331	1.904e-24	109.0	COG4231@1|root,COG4231@2|Bacteria,1VIY6@1239|Firmicutes,24PDQ@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158348_k127_836222_8	945713.IALB_1627	2.981e-25	115.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K03615,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SRR25158348_k127_836222_0	289376.THEYE_A0567	1.083e-124	413.0	COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158348_k127_836222_1	204669.Acid345_4432	2.991e-116	393.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
SRR25158348_k127_836222_5	1254432.SCE1572_22660	3.006e-49	183.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria,2Z01C@29|Myxococcales	28221|Deltaproteobacteria	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158348_k127_837891_0	266117.Rxyl_1165	5.706e-106	360.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158348_k127_840670_0	483219.LILAB_32770	1.253e-102	344.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2YUGW@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158348_k127_840670_1	378806.STAUR_3514	1.443e-26	112.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42R2A@68525|delta/epsilon subdivisions,2WMUK@28221|Deltaproteobacteria,2YVHG@29|Myxococcales	28221|Deltaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158348_k127_842435_1	296591.Bpro_3991	1.255e-112	375.0	COG2227@1|root,COG2227@2|Bacteria,1QU62@1224|Proteobacteria,2VJ8J@28216|Betaproteobacteria,4ACZ9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158348_k127_842435_0	290397.Adeh_4287	3.117e-146	470.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158348_k127_842435_2	1379698.RBG1_1C00001G1541	3.092e-35	148.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	wcaA	-	2.4.1.175,2.4.1.226	ko:K13500	ko00532,ko01100,map00532,map01100	-	R04603,R05931,R05932,R05933,R05934,R07336	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_transf_7C,Glycos_transf_2
SRR25158348_k127_842435_3	330214.NIDE1855	4.27e-11	74.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158348_k127_847359_0	429009.Adeg_0592	5.536e-21	96.0	COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,42GR7@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
SRR25158348_k127_847359_1	926550.CLDAP_05520	4.131e-17	94.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158348_k127_854302_2	521674.Plim_3749	4.44e-40	151.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158348_k127_854302_3	243231.GSU3292	2.497e-33	136.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria,43VCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158348_k127_854302_1	309807.SRU_1117	2.424e-52	198.0	COG0783@1|root,COG0783@2|Bacteria,4P42Z@976|Bacteroidetes,1FJPF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR25158348_k127_854302_6	237368.SCABRO_01044	4.094e-07	57.0	2DRVG@1|root,33D8Q@2|Bacteria,2J19Z@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_854302_5	1046714.AMRX01000006_gene2416	1.577e-08	66.0	COG3063@1|root,COG3271@1|root,COG3063@2|Bacteria,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,4656G@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
SRR25158348_k127_854302_0	1459636.NTE_01417	1.918e-89	307.0	COG0301@1|root,arCOG00038@2157|Archaea,41T1A@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
SRR25158348_k127_854302_7	247490.KSU1_B0424	1.565e-05	51.0	COG0758@1|root,COG0758@2|Bacteria,2IX3D@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SRR25158348_k127_855411_0	237368.SCABRO_01931	6.029e-89	313.0	COG0728@1|root,COG0728@2|Bacteria,2IYP2@203682|Planctomycetes	203682|Planctomycetes	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158348_k127_855411_1	572546.Arcpr_0019	5.572e-11	69.0	COG1694@1|root,arCOG01084@2157|Archaea,2XZ0S@28890|Euryarchaeota,246DI@183980|Archaeoglobi	183980|Archaeoglobi	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158348_k127_857089_0	269799.Gmet_3038	1.544e-26	126.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,43SP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158348_k127_857089_1	1183438.GKIL_3179	1.489e-13	83.0	COG1538@1|root,COG1538@2|Bacteria,1G0B8@1117|Cyanobacteria	1117|Cyanobacteria	MU	outer membrane efflux protein	-	-	-	ko:K03287	-	-	-	-	ko00000	1.B.17	-	-	OEP
SRR25158348_k127_858912_0	550540.Fbal_3271	3.494e-83	286.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158348_k127_858912_1	866775.HMPREF9243_1684	1.136e-31	138.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,27DJF@186827|Aerococcaceae	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158348_k127_859165_1	595460.RRSWK_04160	4.438e-22	101.0	COG0500@1|root,COG2226@2|Bacteria,2IYWE@203682|Planctomycetes	203682|Planctomycetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158348_k127_859165_0	1123242.JH636435_gene1081	8.395e-157	506.0	COG1219@1|root,COG1219@2|Bacteria,2IXDS@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158348_k127_860123_0	469381.Dpep_2028	0.000108	57.0	COG0265@1|root,COG0265@2|Bacteria,3TACF@508458|Synergistetes	508458|Synergistetes	M	TIGRFAM periplasmic serine protease, Do DeqQ family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158348_k127_860123_1	1142394.PSMK_11750	0.0008573	46.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158348_k127_861005_1	1249627.D779_2026	3.139e-53	195.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1WWQJ@135613|Chromatiales	135613|Chromatiales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158348_k127_861005_0	246194.CHY_1808	7.154e-192	609.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42F6I@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158348_k127_861005_4	997346.HMPREF9374_1391	0.0008626	52.0	COG5660@1|root,COG5660@2|Bacteria,1TXBF@1239|Firmicutes,4I692@91061|Bacilli,27CE7@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158348_k127_861005_3	1283284.AZUK01000001_gene2317	4.813e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1Y48V@135624|Aeromonadales	135624|Aeromonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_861005_2	350058.Mvan_0983	6.358e-33	131.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,233Y7@1762|Mycobacteriaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158348_k127_863495_0	994479.GL877878_gene1784	8.715e-10	72.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,PQQ_3,Pkinase
SRR25158348_k127_869230_0	1297742.A176_01168	2.073e-274	859.0	COG0784@1|root,COG0840@1|root,COG2199@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG0840@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2YU1H@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
SRR25158348_k127_870404_2	1123248.KB893328_gene913	4.158e-12	66.0	COG1858@1|root,COG1858@2|Bacteria,4NJ4X@976|Bacteroidetes	976|Bacteroidetes	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_870404_0	1210884.HG799466_gene12908	1.887e-74	264.0	COG1723@1|root,COG1723@2|Bacteria,2J0AJ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_870404_1	1210884.HG799465_gene11812	8.816e-13	81.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	PD40,Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_870871_0	1283283.ATXA01000009_gene3202	1.778e-22	104.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR25158348_k127_870871_1	1382356.JQMP01000001_gene796	8.057e-09	58.0	COG1225@1|root,COG1225@2|Bacteria,2G95Y@200795|Chloroflexi,27YNE@189775|Thermomicrobia	189775|Thermomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158348_k127_874112_0	572547.Amico_0354	1.243e-16	91.0	COG0697@1|root,COG0697@2|Bacteria,3TB45@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158348_k127_874185_3	886293.Sinac_6103	1.131e-61	222.0	COG1212@1|root,COG1212@2|Bacteria,2IYWF@203682|Planctomycetes	203682|Planctomycetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158348_k127_874185_4	289376.THEYE_A1549	6.282e-52	199.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158348_k127_874185_1	1125863.JAFN01000001_gene533	1.151e-74	274.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2X6Y1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158348_k127_874185_0	330214.NIDE3031	1.554e-76	278.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,3J0PZ@40117|Nitrospirae	40117|Nitrospirae	EM	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
SRR25158348_k127_874185_6	247490.KSU1_C0797	8.141e-16	87.0	COG3642@1|root,COG3642@2|Bacteria	247490.KSU1_C0797|-	T	kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_874185_5	649831.L083_2561	4.363e-41	156.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria,4DGJK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158348_k127_874185_2	247490.KSU1_C0795	6.956e-64	232.0	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158348_k127_876264_2	1174528.JH992893_gene5951	3.071e-63	226.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
SRR25158348_k127_876264_0	864069.MicloDRAFT_00026010	3.084e-105	371.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1MWZM@1224|Proteobacteria,2U0GA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
SRR25158348_k127_876264_1	1411123.JQNH01000001_gene607	1.315e-93	336.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,2U3BD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158348_k127_876264_3	1411123.JQNH01000001_gene608	2.994e-51	195.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158348_k127_876264_4	1242864.D187_000449	1.176e-17	87.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158348_k127_876432_0	247490.KSU1_C0411	1.49e-152	497.0	COG1418@1|root,COG1418@2|Bacteria,2IX35@203682|Planctomycetes	203682|Planctomycetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158348_k127_876432_2	313606.M23134_03800	0.0001392	51.0	COG2274@1|root,COG2274@2|Bacteria,4NIGB@976|Bacteroidetes,47UIT@768503|Cytophagia	976|Bacteroidetes	V	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158348_k127_876432_1	720554.Clocl_1407	3.323e-73	254.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,3WHB0@541000|Ruminococcaceae	186801|Clostridia	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158348_k127_880691_1	2002.JOEQ01000004_gene2685	2.38e-80	274.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4EGF5@85012|Streptosporangiales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158348_k127_880691_2	760568.Desku_2542	3.637e-28	117.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,262H0@186807|Peptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158348_k127_880691_3	1121422.AUMW01000025_gene296	2.788e-19	90.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia,263AU@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158348_k127_880691_0	247490.KSU1_D0820	3.797e-202	658.0	COG0532@1|root,COG0532@2|Bacteria,2IXYU@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158348_k127_882663_2	269799.Gmet_1668	1.295e-29	124.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
SRR25158348_k127_882663_0	1123368.AUIS01000020_gene1109	5.937e-89	317.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2NE6V@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
SRR25158348_k127_882663_1	330214.NIDE0222	6.286e-83	286.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158348_k127_888867_3	1279015.KB908467_gene484	0.0003578	51.0	COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria,1T2RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158348_k127_888867_2	756272.Plabr_3187	5.68e-05	55.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158348_k127_888867_0	344747.PM8797T_14294	1.011e-45	188.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
SRR25158348_k127_888867_1	709986.Deima_1544	4.962e-05	53.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158348_k127_894707_0	1121468.AUBR01000001_gene508	2.706e-86	297.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,42FA6@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Nucleotidyl transferase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158348_k127_894707_2	290397.Adeh_1232	4.292e-28	118.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158348_k127_894707_3	190650.CC_0320	1.845e-25	116.0	2DPN6@1|root,332R8@2|Bacteria,1NJK4@1224|Proteobacteria,2UQSV@28211|Alphaproteobacteria,2KJ71@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_894707_1	522306.CAP2UW1_0953	1.64e-85	295.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2VI1Z@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome C peroxidase	ccp	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR25158348_k127_894770_3	583355.Caka_2956	1.679e-26	124.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,46V40@74201|Verrucomicrobia,3K7D2@414999|Opitutae	414999|Opitutae	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_894770_2	5833.PFI0380c	2.846e-34	151.0	COG0242@1|root,KOG3137@2759|Eukaryota,3YBX7@5794|Apicomplexa,3KDPF@422676|Aconoidasida,3YWNX@5819|Haemosporida	422676|Aconoidasida	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158348_k127_894770_0	247490.KSU1_C0976	1.212e-59	218.0	COG0196@1|root,COG0196@2|Bacteria,2IYZQ@203682|Planctomycetes	203682|Planctomycetes	H	riboflavin biosynthesis protein	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158348_k127_894770_1	886293.Sinac_2614	1.903e-35	151.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158348_k127_894770_5	357808.RoseRS_2703	1.865e-10	74.0	COG2304@1|root,COG2304@2|Bacteria,2GACU@200795|Chloroflexi,375FC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158348_k127_894770_4	1307761.L21SP2_3049	1.062e-18	94.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,2JAW9@203691|Spirochaetes	203691|Spirochaetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158348_k127_898312_0	517417.Cpar_1684	2.632e-91	304.0	COG1741@1|root,COG1741@2|Bacteria,1FEUN@1090|Chlorobi	1090|Chlorobi	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158348_k127_898312_2	857087.Metme_3516	3.288e-13	76.0	2C983@1|root,3093Q@2|Bacteria,1QSQN@1224|Proteobacteria,1RW8Y@1236|Gammaproteobacteria,1XGMW@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_898312_1	886293.Sinac_7445	1.831e-14	84.0	COG0526@1|root,COG0526@2|Bacteria,2J147@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158348_k127_898619_0	1333507.AUTQ01000170_gene321	4.567e-79	281.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,1S13M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
SRR25158348_k127_898619_1	1182590.BN5_01194	1.498e-14	77.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria,1YHC9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158348_k127_900734_0	330214.NIDE1971	4.675e-52	194.0	COG3522@1|root,COG3522@2|Bacteria,3J17B@40117|Nitrospirae	40117|Nitrospirae	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
SRR25158348_k127_900734_1	330214.NIDE1969	1.807e-31	139.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria	2|Bacteria	T	FHA domain	impI	-	2.7.11.1	ko:K07169,ko:K08884,ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	3.A.23.1	-	-	FHA
SRR25158348_k127_906257_0	1123508.JH636442_gene4019	5.801e-60	220.0	COG0568@1|root,COG0568@2|Bacteria,2IYCB@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158348_k127_908682_2	1210884.HG799465_gene12018	3.058e-47	176.0	COG0093@1|root,COG0093@2|Bacteria,2IZMA@203682|Planctomycetes	203682|Planctomycetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158348_k127_908682_3	1089550.ATTH01000001_gene2356	3.584e-22	100.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1FJGB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158348_k127_908682_0	247490.KSU1_D0732	1.029e-154	499.0	COG0172@1|root,COG0172@2|Bacteria,2IXGP@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158348_k127_908682_1	448385.sce7609	7.887e-84	288.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158348_k127_909766_2	349163.Acry_1628	9.455e-06	53.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2JRYU@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158348_k127_909766_1	717774.Marme_0302	1.468e-06	61.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,1XR4C@135619|Oceanospirillales	135619|Oceanospirillales	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158348_k127_909766_3	160492.XF_1800	4.881e-05	55.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1X737@135614|Xanthomonadales	135614|Xanthomonadales	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158348_k127_909766_0	32057.KB217483_gene9081	3.804e-11	74.0	COG0607@1|root,COG0607@2|Bacteria,1G56U@1117|Cyanobacteria,1HNBK@1161|Nostocales	1117|Cyanobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
SRR25158348_k127_913367_5	1123389.ATXJ01000017_gene42	5.893e-28	121.0	COG1309@1|root,COG1309@2|Bacteria,1WI1D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158348_k127_913367_3	1382306.JNIM01000001_gene1022	4.374e-66	233.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158348_k127_913367_0	1382306.JNIM01000001_gene1023	3.399e-300	940.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158348_k127_913367_1	485913.Krac_2435	1.44e-105	353.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158348_k127_913367_6	1499967.BAYZ01000105_gene3516	0.0001428	50.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158348_k127_913367_4	316067.Geob_0827	1.935e-63	243.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
SRR25158348_k127_913367_2	1125863.JAFN01000001_gene389	2.657e-85	291.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158348_k127_915424_0	247490.KSU1_C0697	2.97e-123	415.0	COG0608@1|root,COG0608@2|Bacteria,2IXVB@203682|Planctomycetes	203682|Planctomycetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158348_k127_915424_1	1035196.HMPREF9998_00956	8.197e-41	155.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,25QFY@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158348_k127_916791_1	498761.HM1_3037	4.806e-93	312.0	COG2189@1|root,COG2189@2|Bacteria,1UHUQ@1239|Firmicutes,25E35@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158348_k127_916791_4	215803.DB30_5360	5.04e-24	108.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_916791_3	1131266.ARWQ01000001_gene1306	7.917e-60	217.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158348_k127_916791_0	247490.KSU1_C1189	4.305e-105	349.0	COG0152@1|root,COG0152@2|Bacteria,2IY7D@203682|Planctomycetes	203682|Planctomycetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158348_k127_916791_5	498211.CJA_1029	5.158e-21	105.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1FG9C@10|Cellvibrio	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158348_k127_916791_2	697281.Mahau_2356	3.133e-67	232.0	COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia,42FYF@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158348_k127_917418_2	2754.EH55_00110	5.261e-42	156.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32470	Fer2,Fer2_2
SRR25158348_k127_917418_0	886293.Sinac_6836	1.398e-156	520.0	COG1529@1|root,COG1529@2|Bacteria,2IYIN@203682|Planctomycetes	203682|Planctomycetes	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158348_k127_917418_1	1192034.CAP_6380	4.786e-75	268.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2YY4R@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158348_k127_917938_0	1254432.SCE1572_06125	9.713e-167	536.0	COG1524@1|root,COG1524@2|Bacteria,1P235@1224|Proteobacteria,437X7@68525|delta/epsilon subdivisions,2X9QJ@28221|Deltaproteobacteria,2YUMF@29|Myxococcales	28221|Deltaproteobacteria	S	proteins of the AP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158348_k127_925615_0	404589.Anae109_3679	0.0	1116.0	COG0714@1|root,COG1112@1|root,COG0714@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,42PMB@68525|delta/epsilon subdivisions,2WJR9@28221|Deltaproteobacteria,2Z2U9@29|Myxococcales	28221|Deltaproteobacteria	KL	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
SRR25158348_k127_927900_1	477974.Daud_1588	3.593e-10	64.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158348_k127_927900_0	886293.Sinac_5563	1.007e-249	797.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158348_k127_930688_0	945713.IALB_0186	1.314e-06	61.0	COG4675@1|root,COG5276@1|root,COG4675@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Collar,Phage_fiber_2
SRR25158348_k127_9396_2	706587.Desti_5065	2.911e-54	195.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_9396_0	706587.Desti_5065	1.416e-70	248.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158348_k127_9396_1	671143.DAMO_1099	7.587e-55	198.0	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU,PhoU_div
SRR25158348_k127_946619_0	1121378.KB899747_gene3415	1.64e-30	126.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
SRR25158348_k127_946619_1	1487953.JMKF01000045_gene2892	0.0002995	53.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
SRR25158348_k127_951347_7	1267533.KB906734_gene3801	1.812e-07	54.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158348_k127_951347_0	635013.TherJR_1319	1.921e-187	597.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,260CE@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158348_k127_951347_6	926566.Terro_1124	8.639e-10	70.0	COG2217@1|root,COG2217@2|Bacteria,3Y39H@57723|Acidobacteria,2JHMU@204432|Acidobacteriia	204432|Acidobacteriia	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158348_k127_951347_3	411474.COPEUT_02191	1.833e-50	184.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158348_k127_951347_8	69042.WH5701_05540	2.489e-05	53.0	COG0103@1|root,COG0103@2|Bacteria,1G5NH@1117|Cyanobacteria,1H09B@1129|Synechococcus	1117|Cyanobacteria	J	Belongs to the universal ribosomal protein uS9 family	rps9	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158348_k127_951347_4	1219084.AP014508_gene1070	5.18e-22	101.0	COG0103@1|root,COG0103@2|Bacteria,2GD2Y@200918|Thermotogae	200918|Thermotogae	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158348_k127_951347_1	224324.aq_273	4.169e-110	374.0	COG0436@1|root,COG0436@2|Bacteria,2G3NP@200783|Aquificae	200783|Aquificae	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158348_k127_951347_2	871968.DESME_13755	6.536e-55	199.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158348_k127_951347_5	886293.Sinac_1302	4.999e-19	92.0	COG0457@1|root,COG0457@2|Bacteria,2J0KQ@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_951914_0	671143.DAMO_1208	8.722e-196	621.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158348_k127_951914_1	221360.RS9917_05115	3.493e-05	50.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria,1GYVU@1129|Synechococcus	1117|Cyanobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
SRR25158348_k127_954349_0	479434.Sthe_3204	7.695e-114	384.0	COG0167@1|root,COG0167@2|Bacteria,2GBTE@200795|Chloroflexi,27Y32@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158348_k127_954349_1	1382356.JQMP01000003_gene1755	1.558e-44	166.0	COG1956@1|root,COG1956@2|Bacteria,2GA0T@200795|Chloroflexi,27YG6@189775|Thermomicrobia	189775|Thermomicrobia	T	GAF domain	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
SRR25158348_k127_954349_2	1460634.JCM19037_3274	1.725e-16	90.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli	91061|Bacilli	K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158348_k127_956138_0	1338011.BD94_2399	4.9e-08	57.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia,34Q1A@308865|Elizabethkingia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158348_k127_957074_1	1569209.BBPH01000025_gene232	2.271e-40	156.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,2PU0Z@265|Paracoccus	28211|Alphaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158348_k127_957074_0	1304880.JAGB01000001_gene813	6.318e-88	313.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia	186801|Clostridia	S	peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
SRR25158348_k127_957074_2	886293.Sinac_1734	1.541e-14	86.0	2EK1E@1|root,33DRX@2|Bacteria,2J1JB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Prok-RING_1
SRR25158348_k127_959569_2	247490.KSU1_D0069	1.784e-22	102.0	COG1450@1|root,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
SRR25158348_k127_959569_0	1343739.PAP_03130	1.143e-41	163.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci	183968|Thermococci	S	Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158348_k127_959569_1	588581.Cpap_0842	3.242e-36	140.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158348_k127_960176_1	484770.UFO1_2563	1.665e-32	139.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4H3BC@909932|Negativicutes	909932|Negativicutes	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
SRR25158348_k127_960176_2	391735.Veis_1125	9.333e-14	74.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2VU8S@28216|Betaproteobacteria,4AF1W@80864|Comamonadaceae	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
SRR25158348_k127_960176_0	138119.DSY2978	1.356e-34	134.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia,260DF@186807|Peptococcaceae	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
SRR25158348_k127_961695_2	404380.Gbem_1633	6.3e-75	269.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,43TVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein CapD	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158348_k127_961695_0	1158338.JNLJ01000001_gene807	3.823e-168	547.0	COG0449@1|root,COG0449@2|Bacteria,2G3KT@200783|Aquificae	200783|Aquificae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158348_k127_961695_1	756272.Plabr_4445	4.815e-82	283.0	COG0451@1|root,COG0451@2|Bacteria,2IYGP@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158348_k127_961695_3	1173020.Cha6605_3242	5.403e-24	116.0	2ABPF@1|root,3115E@2|Bacteria,1GC9B@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_961695_4	37919.EP51_02790	2.257e-07	61.0	COG0515@1|root,COG3055@1|root,COG0515@2|Bacteria,COG3055@2|Bacteria,2HEN9@201174|Actinobacteria,4FVW7@85025|Nocardiaceae	201174|Actinobacteria	KLT	Galactose oxidase, central domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Kelch_1,Pkinase
SRR25158348_k127_962794_1	344747.PM8797T_14319	6.16e-33	134.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158348_k127_962794_0	1123242.JH636436_gene130	9.494e-168	559.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158348_k127_962794_2	237609.PSAKL28_10830	6.57e-05	53.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Negative regulator of sigma E activity	rseB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
SRR25158348_k127_966637_0	498761.HM1_2224	2.512e-35	142.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158348_k127_966637_3	1120973.AQXL01000128_gene2856	3.949e-11	75.0	COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HG3R@91061|Bacilli,278PI@186823|Alicyclobacillaceae	91061|Bacilli	NU	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
SRR25158348_k127_966637_1	1121423.JONT01000006_gene2500	1.03e-34	148.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,260SV@186807|Peptococcaceae	186801|Clostridia	N	flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
SRR25158348_k127_966637_2	2423.NA23_0206375	5.301e-14	85.0	COG1766@1|root,COG1766@2|Bacteria,2GCH8@200918|Thermotogae	200918|Thermotogae	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
SRR25158348_k127_966637_4	1336241.JAEB01000003_gene507	0.0001267	49.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
SRR25158348_k127_967093_0	1340493.JNIF01000003_gene2503	2.659e-73	262.0	COG0577@1|root,COG0577@2|Bacteria,3Y4C7@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158348_k127_967093_2	1396141.BATP01000030_gene3562	6.287e-31	132.0	COG3428@1|root,COG3428@2|Bacteria,46VTZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158348_k127_967093_1	1396141.BATP01000030_gene3561	9.276e-52	190.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158348_k127_968721_0	1184267.A11Q_1043	0.0003163	53.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2MTDI@213481|Bdellovibrionales,2WJ7D@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158348_k127_973481_1	1123242.JH636438_gene5694	1.513e-120	397.0	COG1290@1|root,COG1290@2|Bacteria,2IYI0@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158348_k127_973481_0	1201288.M900_0271	1.277e-122	398.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome b b6 domain	pcmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR25158348_k127_973481_3	886293.Sinac_1829	7.328e-41	158.0	COG0723@1|root,COG0723@2|Bacteria,2IZ3E@203682|Planctomycetes	203682|Planctomycetes	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158348_k127_973481_6	357808.RoseRS_3392	1.25e-06	60.0	COG1413@1|root,COG1413@2|Bacteria,2G6UU@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158348_k127_973481_5	1005048.CFU_2545	5.532e-22	111.0	COG0457@1|root,COG4676@1|root,COG0457@2|Bacteria,COG4676@2|Bacteria,1QZ6W@1224|Proteobacteria,2VKUR@28216|Betaproteobacteria,475SK@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2135,VIT
SRR25158348_k127_973481_2	1123508.JH636452_gene7057	5.069e-61	243.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2J2J0@203682|Planctomycetes	203682|Planctomycetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT,VWA_3
SRR25158348_k127_973481_4	1267533.KB906733_gene3438	9.298e-23	104.0	COG1595@1|root,COG1595@2|Bacteria,3Y8V2@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158348_k127_975605_2	653733.Selin_0884	1.573e-20	106.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158348_k127_975605_1	886293.Sinac_2284	1.856e-91	322.0	COG1034@1|root,COG1034@2|Bacteria,2IY04@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2,Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRR25158348_k127_975605_0	671143.DAMO_2696	8.433e-167	535.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158348_k127_97730_0	1304872.JAGC01000003_gene2864	5.982e-166	535.0	COG3866@1|root,COG3866@2|Bacteria,1RFAV@1224|Proteobacteria	1224|Proteobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158348_k127_97730_1	543728.Vapar_5767	9.595e-10	64.0	COG2050@1|root,COG2050@2|Bacteria,1N8E6@1224|Proteobacteria,2VWZG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158348_k127_977928_0	404589.Anae109_3101	3.821e-151	491.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158348_k127_977928_1	1173028.ANKO01000017_gene255	1.866e-72	249.0	COG0431@1|root,COG0431@2|Bacteria,1G0HA@1117|Cyanobacteria,1HAB8@1150|Oscillatoriales	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158348_k127_980514_1	439481.Aboo_0187	2.459e-21	102.0	COG1109@1|root,arCOG00767@2157|Archaea,2Y66D@28890|Euryarchaeota,3F34Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158348_k127_980514_0	252305.OB2597_06550	1.337e-55	202.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria,2PD63@252301|Oceanicola	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158348_k127_980665_0	1382306.JNIM01000001_gene2570	5.641e-182	576.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158348_k127_980665_1	1198452.Jab_1c01540	1.095e-76	281.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,4736H@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
SRR25158348_k127_984130_3	1089553.Tph_c26180	5.617e-08	56.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
SRR25158348_k127_984130_0	502025.Hoch_2654	1.356e-130	437.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,437G6@68525|delta/epsilon subdivisions,2X2NS@28221|Deltaproteobacteria,2YU1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158348_k127_984130_2	207559.Dde_2396	1.088e-08	68.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2MD4U@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158348_k127_984130_1	557598.LHK_03237	4.46e-26	108.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales	206351|Neisseriales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158348_k127_985921_6	1121422.AUMW01000001_gene2513	4.577e-22	101.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158348_k127_985921_0	1125863.JAFN01000001_gene2585	1.476e-177	569.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158348_k127_985921_1	1298593.TOL_3678	8.047e-106	374.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XH3Y@135619|Oceanospirillales	135619|Oceanospirillales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158348_k127_985921_5	1278073.MYSTI_05598	1.155e-63	233.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
SRR25158348_k127_985921_4	290397.Adeh_0171	2.708e-73	260.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158348_k127_985921_2	518766.Rmar_0947	3.162e-100	353.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158348_k127_985921_3	1254432.SCE1572_00430	7.815e-85	293.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2YYG6@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158348_k127_985921_7	768066.HELO_3830	0.0005086	52.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XHR1@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.3.1.1,2.7.2.8	ko:K00930,ko:K22478	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158348_k127_986898_0	1123508.JH636439_gene1391	1.102e-119	403.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158348_k127_986898_1	1313421.JHBV01000019_gene5349	7.079e-76	261.0	COG4912@1|root,COG4912@2|Bacteria,4NJ0V@976|Bacteroidetes,1ITTR@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158348_k127_986898_3	316057.RPD_0201	1.668e-29	133.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,3JYUR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158348_k127_986898_4	378806.STAUR_8260	1.964e-23	110.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158348_k127_986898_2	1121396.KB893052_gene3420	4.176e-44	177.0	COG1193@1|root,COG1193@2|Bacteria,1NX1A@1224|Proteobacteria,4305V@68525|delta/epsilon subdivisions,2WV73@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Protein-arginine deiminase (PAD) middle domain	-	-	-	-	-	-	-	-	-	-	-	-	PAD
SRR25158348_k127_98868_2	1144275.COCOR_05839	1.334e-15	91.0	2DS2B@1|root,33E7G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_98868_1	593750.Metfor_0193	1.882e-54	209.0	COG0500@1|root,arCOG04989@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158348_k127_98868_0	1206737.BAGF01000151_gene6162	1.631e-55	212.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria	201174|Actinobacteria	H	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158348_k127_988733_2	1521187.JPIM01000050_gene3442	5.992e-69	252.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,376B5@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158348_k127_988733_6	247490.KSU1_C0956	8.555e-31	126.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Beta-lactamase,DUF3471,OmpA,PD40,TPR_16,TPR_2,TPR_6,TPR_8,WG_beta_rep
SRR25158348_k127_988733_5	886293.Sinac_3189	5.8e-32	134.0	COG3350@1|root,COG3350@2|Bacteria,2IZZU@203682|Planctomycetes	203682|Planctomycetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
SRR25158348_k127_988733_1	861299.J421_4280	6.07e-99	349.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158348_k127_988733_3	234267.Acid_5203	6.513e-59	228.0	COG0276@1|root,COG0276@2|Bacteria,3Y3B0@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158348_k127_988733_0	1192034.CAP_7271	2.526e-108	361.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SRR25158348_k127_988733_4	1123508.JH636441_gene3231	3.679e-44	183.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158348_k127_994043_1	530564.Psta_3212	1.026e-111	371.0	COG1449@1|root,COG1449@2|Bacteria,2IY67@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158348_k127_994043_0	290397.Adeh_0135	3.734e-138	454.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158348_k127_994043_6	509191.AEDB02000082_gene2564	4.11e-13	79.0	COG0265@1|root,COG0265@2|Bacteria,1VKPF@1239|Firmicutes,24WM6@186801|Clostridia,3WNMZ@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_994043_3	1232410.KI421428_gene1113	5.981e-70	241.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,43UUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158348_k127_994043_5	177439.DP0983	1.348e-16	86.0	2EA4Q@1|root,3349M@2|Bacteria,1NEN1@1224|Proteobacteria,42WI0@68525|delta/epsilon subdivisions,2WRFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158348_k127_994043_2	886293.Sinac_6565	5.832e-99	332.0	COG1085@1|root,COG1085@2|Bacteria,2IX2C@203682|Planctomycetes	203682|Planctomycetes	C	galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
SRR25158348_k127_994043_4	234267.Acid_6603	3.538e-18	91.0	COG1449@1|root,COG1449@2|Bacteria,3Y36M@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SRR25158348_k127_994376_1	338963.Pcar_0731	5.575e-63	227.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2WN02@28221|Deltaproteobacteria,43TCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase
SRR25158348_k127_994376_0	1125863.JAFN01000001_gene207	1.182e-97	325.0	COG1028@1|root,COG1028@2|Bacteria,1QXA0@1224|Proteobacteria,42UQH@68525|delta/epsilon subdivisions,2WQ5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158348_k127_994376_2	526227.Mesil_2497	2.698e-05	52.0	COG0747@1|root,COG0747@2|Bacteria,1WIYQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158348_k127_996430_1	247490.KSU1_C0310	7.173e-37	149.0	COG3880@1|root,COG3880@2|Bacteria,2J09E@203682|Planctomycetes	203682|Planctomycetes	S	protein with conserved CXXC pairs	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
SRR25158348_k127_996430_2	767817.Desgi_0326	3.612e-07	60.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,24JE8@186801|Clostridia,2621Q@186807|Peptococcaceae	186801|Clostridia	S	PFAM UvrB uvrC	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
SRR25158348_k127_996430_0	237368.SCABRO_02407	2.523e-143	467.0	COG0269@1|root,COG0684@1|root,COG0269@2|Bacteria,COG0684@2|Bacteria,2J0G2@203682|Planctomycetes	203682|Planctomycetes	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
SRR25158348_k127_996430_3	1408254.T458_23425	7.068e-06	59.0	COG2304@1|root,COG2304@2|Bacteria,1V0C8@1239|Firmicutes,4HDR1@91061|Bacilli,26RBX@186822|Paenibacillaceae	91061|Bacilli	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158348_k127_998949_4	1121378.KB899764_gene3337	0.0001496	44.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158348_k127_998949_0	483219.LILAB_04820	1.193e-63	222.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158348_k127_998949_1	1121035.AUCH01000005_gene125	1.158e-58	217.0	COG2199@1|root,COG3706@2|Bacteria,1MYK0@1224|Proteobacteria	1224|Proteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158348_k127_998949_2	1165096.ARWF01000001_gene1808	1.83e-29	130.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,2VTTP@28216|Betaproteobacteria,2KKD2@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
SRR25158348_k127_998949_3	1449063.JMLS01000001_gene4442	1.918e-07	55.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,26YAQ@186822|Paenibacillaceae	91061|Bacilli	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158348_k127_999742_3	530564.Psta_4547	3.823e-93	310.0	COG0683@1|root,COG0683@2|Bacteria,2IYKT@203682|Planctomycetes	203682|Planctomycetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158348_k127_999742_0	530564.Psta_4548	8.219e-117	384.0	COG0559@1|root,COG0559@2|Bacteria,2IWS7@203682|Planctomycetes	203682|Planctomycetes	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
SRR25158348_k127_999742_1	530564.Psta_4549	4.662e-107	374.0	COG4177@1|root,COG4177@2|Bacteria,2IYM8@203682|Planctomycetes	203682|Planctomycetes	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158348_k127_999742_2	1210884.HG799465_gene11945	1.375e-100	349.0	COG0411@1|root,COG0411@2|Bacteria,2IX2P@203682|Planctomycetes	203682|Planctomycetes	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158348_k127_999742_4	1123508.JH636445_gene6816	8.094e-23	111.0	COG0410@1|root,COG0410@2|Bacteria,2IYQW@203682|Planctomycetes	203682|Planctomycetes	E	ABC transporter	-	-	-	ko:K01996,ko:K11963	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
## 2085 queries scanned
## Total time (seconds): 106.77376914024353
## Rate: 19.53 q/s