## Thu Feb 19 02:34:19 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158351_bin.17.fa -m mmseqs --output SRR25158351_bin.17 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158351_bin.17 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158351_k127_1059253_76	1110697.NCAST_32_04660	7.521e-15	79.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria,4G2Q6@85025|Nocardiaceae	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158351_k127_1059253_71	1380356.JNIK01000015_gene2546	7.959e-23	109.0	2BPDR@1|root,32I5V@2|Bacteria,2H6IS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1059253_14	105422.BBPM01000017_gene2288	6.703e-128	424.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,2NHGW@228398|Streptacidiphilus	201174|Actinobacteria	K	RNB	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158351_k127_1059253_40	1278073.MYSTI_03354	1.199e-73	262.0	COG1611@1|root,COG1611@2|Bacteria,1R7TB@1224|Proteobacteria,43F31@68525|delta/epsilon subdivisions,2X36V@28221|Deltaproteobacteria,2YUKD@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1059253_21	479434.Sthe_1347	8.724e-103	357.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158351_k127_1059253_17	58123.JOFJ01000001_gene3088	8.646e-114	376.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4EI63@85012|Streptosporangiales	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158351_k127_1059253_13	1313172.YM304_33370	6.442e-134	449.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CNNX@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158351_k127_1059253_65	1306174.JODP01000006_gene3139	5.254e-33	136.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158351_k127_1059253_31	1313172.YM304_33390	1.624e-90	306.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4CN04@84992|Acidimicrobiia	84992|Acidimicrobiia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158351_k127_1059253_33	471852.Tcur_3385	2.63e-88	300.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EMUX@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1059253_69	526225.Gobs_3590	1.781e-24	109.0	2E7QZ@1|root,3326A@2|Bacteria,2GR1A@201174|Actinobacteria,4EW8P@85013|Frankiales	201174|Actinobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158351_k127_1059253_59	1229780.BN381_40081	3.033e-41	166.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,3UWTG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_1059253_3	1210045.ALNP01000016_gene1907	3.847e-246	789.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158351_k127_1059253_50	1121017.AUFG01000005_gene986	7.438e-47	172.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4FGP8@85021|Intrasporangiaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158351_k127_1059253_58	469371.Tbis_1693	2.856e-41	159.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158351_k127_1059253_53	1283283.ATXA01000001_gene785	4.441e-45	179.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4ESMT@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MerR	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158351_k127_1059253_62	696281.Desru_1270	2.123e-36	150.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158351_k127_1059253_54	882083.SacmaDRAFT_2776	7.944e-45	167.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4DXJH@85010|Pseudonocardiales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158351_k127_1059253_52	1229780.BN381_40086	7.983e-46	171.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,3UWPC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158351_k127_1059253_64	671143.DAMO_2813	6.252e-35	138.0	COG1102@1|root,COG1102@2|Bacteria,2NRB0@2323|unclassified Bacteria	2|Bacteria	F	Cytidylate kinase-like family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
SRR25158351_k127_1059253_18	1313172.YM304_25740	6.576e-113	377.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CMQS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Glycine cleavage T-protein C-terminal barrel domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_1059253_0	1288083.AUKR01000028_gene59	0.0	1292.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158351_k127_1059253_81	1168065.DOK_18625	3.052e-05	56.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,1J72D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
SRR25158351_k127_1059253_72	1229780.BN381_400023	2.11e-21	106.0	COG0454@1|root,COG0456@2|Bacteria,2HBQK@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1059253_46	1210045.ALNP01000015_gene1648	4.292e-57	218.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158351_k127_1059253_6	1313172.YM304_25950	2.039e-221	707.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158351_k127_1059253_79	1121377.KB906398_gene2748	1.115e-10	72.0	COG1597@1|root,COG1597@2|Bacteria,1WI0N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Diacylglycerol kinase, catalytic	bmrU	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158351_k127_1059253_7	1120936.KB907219_gene3239	2.241e-218	708.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4EH6A@85012|Streptosporangiales	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158351_k127_1059253_48	1229780.BN381_400031	2.351e-51	190.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,3UWSI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158351_k127_1059253_78	292459.STH1894	3.8e-11	70.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,24V8A@186801|Clostridia	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158351_k127_1059253_51	1313172.YM304_26000	4.23e-46	183.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158351_k127_1059253_60	1229780.BN381_400037	7.305e-40	158.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,3UWRN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158351_k127_1059253_43	1229780.BN381_400038	6.246e-63	233.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,3UWZY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158351_k127_1059253_44	1313172.YM304_14840	2.824e-62	227.0	COG2378@1|root,COG2378@2|Bacteria,2HGFE@201174|Actinobacteria,4CND2@84992|Acidimicrobiia	84992|Acidimicrobiia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
SRR25158351_k127_1059253_28	1229780.BN381_400040	1.341e-94	325.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158351_k127_1059253_4	1313172.YM304_26020	6.93e-236	741.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158351_k127_1059253_37	1229780.BN381_400042	1.25e-81	280.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,3UX82@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Proteasome subunit	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158351_k127_1059253_35	1313172.YM304_26050	2.107e-83	286.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4CMX8@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158351_k127_1059253_73	1150864.MILUP08_43406	4.615e-21	108.0	2EFG7@1|root,3398W@2|Bacteria,2ID0P@201174|Actinobacteria,4DGI7@85008|Micromonosporales	201174|Actinobacteria	L	Recombination endonuclease VII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_7
SRR25158351_k127_1059253_10	1121877.JQKF01000002_gene1619	5.876e-178	570.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CMSZ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pup-ligase protein	dop	-	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158351_k127_1059253_2	1313172.YM304_26090	2.539e-256	801.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CMRU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Proteasomal ATPase OB/ID domain	arc	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158351_k127_1059253_61	1229780.BN381_410005	5.287e-38	145.0	COG1141@1|root,COG1141@2|Bacteria,2IKKX@201174|Actinobacteria	201174|Actinobacteria	C	ferredoxin	fdxG	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
SRR25158351_k127_1059253_57	675635.Psed_0948	1.588e-41	166.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DYPN@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM channel protein, hemolysin III family	hlyI	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158351_k127_1059253_49	521096.Tpau_3927	1.676e-47	188.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158351_k127_1059253_34	1313172.YM304_26120	1.59e-85	299.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CN0Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158351_k127_1059253_15	1229780.BN381_410007	7.555e-123	401.0	COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria	201174|Actinobacteria	D	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158351_k127_1059253_75	1122247.C731_3323	1.78e-15	78.0	COG2104@1|root,COG2104@2|Bacteria,2H07J@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_1059253_77	1313172.YM304_26170	1.501e-11	78.0	28R1E@1|root,2ZDG1@2|Bacteria,2HDQB@201174|Actinobacteria,4CNE2@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158351_k127_1059253_47	1313172.YM304_26190	3.498e-56	218.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158351_k127_1059253_8	1313172.YM304_26210	2.649e-201	640.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CMW5@84992|Acidimicrobiia	201174|Actinobacteria	CJ	CoA binding domain	acdA1	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158351_k127_1059253_42	1229780.BN381_410015	1.102e-65	231.0	COG0045@1|root,COG0045@2|Bacteria,2I3K9@201174|Actinobacteria	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
SRR25158351_k127_1059253_27	1230476.C207_00461	1.313e-95	332.0	COG0318@1|root,COG0318@2|Bacteria,1QCB3@1224|Proteobacteria,2UPUU@28211|Alphaproteobacteria,3K3RB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1059253_55	391625.PPSIR1_32158	2.081e-42	166.0	COG0463@1|root,COG0463@2|Bacteria,1NKDW@1224|Proteobacteria,42XGP@68525|delta/epsilon subdivisions,2WTBI@28221|Deltaproteobacteria,2YUTR@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_1059253_45	1121017.AUFG01000015_gene2648	9.553e-62	229.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4FFXN@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3332	Amidohydro_1
SRR25158351_k127_1059253_30	530564.Psta_0358	8.787e-92	330.0	COG4398@1|root,COG4398@2|Bacteria,2IXYT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158351_k127_1059253_5	1313172.YM304_26280	5.056e-224	718.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CNKC@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158351_k127_1059253_20	1120949.KB903294_gene3987	1.481e-105	372.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4D9UT@85008|Micromonosporales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158351_k127_1059253_68	405948.SACE_4427	1.928e-30	136.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4E3MK@85010|Pseudonocardiales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158351_k127_1059253_63	1120919.AUBI01000015_gene2781	2.445e-36	150.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U77K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	6-phosphogluconolactonase	pgl	-	2.7.1.12,3.1.1.31	ko:K00851,ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R01737,R02035	RC00002,RC00017,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158351_k127_1059253_1	1229780.BN381_410025	4.314e-314	980.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria	201174|Actinobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158351_k127_1059253_16	1380394.JADL01000002_gene1526	4.788e-122	420.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2JPGW@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1059253_24	1313172.YM304_26310	6.147e-98	334.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CMXM@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158351_k127_1059253_19	1313172.YM304_26330	4.016e-106	357.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4CN2B@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
SRR25158351_k127_1059253_56	1313172.YM304_26370	8.769e-42	171.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4CNDA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
SRR25158351_k127_1059253_12	1313172.YM304_26380	6.542e-154	500.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CMS1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158351_k127_1059253_39	1313172.YM304_20280	1.146e-74	263.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1059253_38	405948.SACE_2746	2.951e-75	264.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4E2VH@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1059253_66	1229780.BN381_80373	7.55e-33	134.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,3UXJW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Chaperonin 10 Kd subunit	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158351_k127_1059253_32	525909.Afer_1711	1.767e-88	305.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CMQ7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158351_k127_1059253_67	937777.Deipe_0801	1.579e-31	132.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158351_k127_1059253_41	106370.Francci3_1654	3.55e-72	250.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158351_k127_1059253_26	1382306.JNIM01000001_gene837	4.475e-96	323.0	COG1131@1|root,COG1131@2|Bacteria,2G7SA@200795|Chloroflexi	200795|Chloroflexi	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1059253_22	1313172.YM304_37400	7.574e-102	342.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CMXY@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158351_k127_1059253_11	1229780.BN381_250066	3.319e-162	519.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1059253_70	1313172.YM304_13980	3.063e-24	116.0	COG1184@1|root,COG1184@2|Bacteria,2H70W@201174|Actinobacteria	201174|Actinobacteria	J	Initiation factor 2 subunit family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1059253_29	1313172.YM304_37360	6.001e-93	319.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4CN7J@84992|Acidimicrobiia	84992|Acidimicrobiia	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158351_k127_1059253_9	35754.JNYJ01000046_gene3102	2.91e-186	597.0	COG1520@1|root,COG1520@2|Bacteria,2I9S4@201174|Actinobacteria,4D97G@85008|Micromonosporales	201174|Actinobacteria	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158351_k127_1059253_25	1254432.SCE1572_23945	6.698e-97	344.0	COG2159@1|root,COG2159@2|Bacteria,1PZGI@1224|Proteobacteria,435YS@68525|delta/epsilon subdivisions,2X9TW@28221|Deltaproteobacteria,2Z1SH@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_1059253_36	58123.JOFJ01000014_gene4980	9.015e-83	283.0	COG1028@1|root,COG1028@2|Bacteria,2IEID@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1059253_23	1229780.BN381_240011	3.604e-101	336.0	COG0258@1|root,COG0258@2|Bacteria,2H2A3@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease, C-terminal SAM fold	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158351_k127_105947_12	1283299.AUKG01000001_gene2768	1.067e-85	289.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CS0R@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158351_k127_105947_32	351607.Acel_0549	7.866e-20	91.0	COG4770@1|root,COG4770@2|Bacteria,2I2DF@201174|Actinobacteria,4EXEZ@85013|Frankiales	201174|Actinobacteria	I	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158351_k127_105947_25	2074.JNYD01000001_gene6097	9.841e-39	154.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E438@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_105947_20	1313172.YM304_09590	1.186e-49	188.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CNXW@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158351_k127_105947_16	1229780.BN381_310049	4.171e-56	205.0	COG1131@1|root,COG1131@2|Bacteria,2IRXJ@201174|Actinobacteria	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158351_k127_105947_19	1313172.YM304_09610	3.476e-52	199.0	COG2386@1|root,COG2386@2|Bacteria,2HG7F@201174|Actinobacteria,4CN4H@84992|Acidimicrobiia	84992|Acidimicrobiia	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158351_k127_105947_14	1121877.JQKF01000016_gene155	7.374e-74	259.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CN1E@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158351_k127_105947_35	1146883.BLASA_3084	4.438e-14	81.0	COG2332@1|root,COG2332@2|Bacteria,2GTPS@201174|Actinobacteria	201174|Actinobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158351_k127_105947_1	1313172.YM304_09640	5.724e-200	645.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CMX6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome c-type biogenesis protein CcmF C-terminal	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158351_k127_105947_31	1121378.KB899740_gene3841	4.092e-21	100.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	dsbE	-	-	ko:K02199,ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
SRR25158351_k127_105947_33	1146883.BLASA_3081	3.98e-17	91.0	COG0457@1|root,COG3088@1|root,COG0457@2|Bacteria,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria	201174|Actinobacteria	O	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158351_k127_105947_21	1382306.JNIM01000001_gene3962	1.666e-49	187.0	COG0652@1|root,COG0652@2|Bacteria,2G6RE@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158351_k127_105947_0	1121877.JQKF01000022_gene2302	4.25e-322	1002.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CMQB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158351_k127_105947_37	1122611.KB903980_gene3458	1.698e-05	53.0	2B7FC@1|root,320J5@2|Bacteria,2H49X@201174|Actinobacteria,4ENV2@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_105947_30	1229780.BN381_10166	2.733e-25	112.0	2FG55@1|root,3481N@2|Bacteria	2|Bacteria	S	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158351_k127_105947_17	525368.HMPREF0591_2244	3.861e-53	191.0	COG1487@1|root,COG1487@2|Bacteria,2ISE2@201174|Actinobacteria,23B4F@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158351_k127_105947_23	512565.AMIS_66060	1.764e-41	169.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_105947_7	525904.Tter_1163	1.084e-107	363.0	COG1032@1|root,COG1032@2|Bacteria,2NQJQ@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158351_k127_105947_6	1229780.BN381_130174	1.087e-108	365.0	COG0151@1|root,COG0151@2|Bacteria,2I60F@201174|Actinobacteria	201174|Actinobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
SRR25158351_k127_105947_22	1121877.JQKF01000024_gene2390	3.515e-48	184.0	COG0694@1|root,COG0694@2|Bacteria,2HGAJ@201174|Actinobacteria,4CN9Q@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	NifU
SRR25158351_k127_105947_13	1121877.JQKF01000012_gene346	2.525e-78	268.0	COG2043@1|root,COG2043@2|Bacteria,2ISFS@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SRR25158351_k127_105947_18	1173028.ANKO01000170_gene3361	6.119e-53	194.0	COG0346@1|root,COG0346@2|Bacteria,1GAIM@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_105947_9	1229780.BN381_310060	2.809e-97	333.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,3UWEF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158351_k127_105947_26	1121877.JQKF01000016_gene162	6.408e-36	145.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158351_k127_105947_3	1229780.BN381_310061	2.475e-132	433.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,3UWC1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158351_k127_105947_24	543632.JOJL01000001_gene7854	3.157e-41	169.0	COG4907@1|root,COG4907@2|Bacteria,2IBZ3@201174|Actinobacteria,4DBRQ@85008|Micromonosporales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158351_k127_105947_34	525909.Afer_0348	2.219e-15	83.0	2E3M2@1|root,31DE4@2|Bacteria,2HH0X@201174|Actinobacteria,4CP16@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158351_k127_105947_11	1229780.BN381_310065	3.761e-89	305.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158351_k127_105947_4	1229780.BN381_310066	6.993e-117	396.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158351_k127_105947_5	1313172.YM304_09850	7.02e-115	387.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
SRR25158351_k127_105947_29	1229780.BN381_310068	1.061e-30	126.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,3UWR8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158351_k127_105947_27	1410616.JHXE01000020_gene2662	6.444e-36	147.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3NGAK@46205|Pseudobutyrivibrio	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158351_k127_105947_15	1313172.YM304_09900	1.107e-71	253.0	COG1597@1|root,COG1597@2|Bacteria,2HH1A@201174|Actinobacteria,4CP1H@84992|Acidimicrobiia	2|Bacteria	G	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158351_k127_105947_10	469383.Cwoe_5791	5.226e-93	310.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158351_k127_105947_28	98439.AJLL01000063_gene1059	3.562e-33	139.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158351_k127_105947_8	1380347.JNII01000005_gene3483	5.268e-101	350.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4ERIQ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158351_k127_105947_2	479434.Sthe_0078	2.206e-155	507.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1100043_35	500153.JOEK01000001_gene3877	1.278e-68	250.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_1100043_42	1273125.Rrhod_3459	9.819e-49	185.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4FVBH@85025|Nocardiaceae	201174|Actinobacteria	L	endonuclease III	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158351_k127_1100043_32	1313172.YM304_02070	2.952e-76	274.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4CN3U@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	Peptidase C26	-	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158351_k127_1100043_76	1229780.BN381_70025	2.204e-06	61.0	28YVQ@1|root,2ZKNY@2|Bacteria,2HCMJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_9	525909.Afer_0085	3.727e-160	514.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1100043_54	1211815.CBYP010000067_gene112	2.248e-33	139.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1100043_44	452863.Achl_2921	3.949e-46	176.0	2EQ8K@1|root,33HUV@2|Bacteria,2H13Z@201174|Actinobacteria	201174|Actinobacteria	S	Camelysin metallo-endopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M73
SRR25158351_k127_1100043_48	1068980.ARVW01000001_gene6886	4.901e-39	161.0	COG2197@1|root,COG2197@2|Bacteria,2GJ29@201174|Actinobacteria,4E4RN@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158351_k127_1100043_40	452863.Achl_2921	8.641e-50	186.0	2EQ8K@1|root,33HUV@2|Bacteria,2H13Z@201174|Actinobacteria	201174|Actinobacteria	S	Camelysin metallo-endopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M73
SRR25158351_k127_1100043_38	926554.KI912674_gene2544	1.922e-53	207.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1WMF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS
SRR25158351_k127_1100043_67	1229780.BN381_100177	2.471e-14	85.0	COG1748@1|root,COG1748@2|Bacteria,2H8X8@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_80	1121935.AQXX01000025_gene1583	0.0002967	48.0	2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_71	1229203.KI301992_gene2665	1.517e-08	65.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,3UX0P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR25158351_k127_1100043_2	525909.Afer_0006	2.577e-281	886.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CMSQ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA Topoisomerase IV	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158351_k127_1100043_4	1405498.SSIM_01035	5.619e-206	660.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,4GXED@90964|Staphylococcaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158351_k127_1100043_68	1123024.AUII01000002_gene879	1.888e-12	73.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4E3Q7@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158351_k127_1100043_24	1313172.YM304_00030	9.18e-95	323.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CN4M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158351_k127_1100043_21	1229780.BN381_100168	1.718e-99	337.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,3UWB4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158351_k127_1100043_13	1089455.MOPEL_083_00410	1.305e-133	449.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4F6PD@85018|Dermatophilaceae	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158351_k127_1100043_75	1297570.MESS4_120157	1.487e-06	57.0	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,43KW1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158351_k127_1100043_63	1120934.KB894421_gene2520	9.053e-26	116.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158351_k127_1100043_49	1121877.JQKF01000017_gene193	1.124e-37	155.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CN42@84992|Acidimicrobiia	84992|Acidimicrobiia	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158351_k127_1100043_43	1313172.YM304_42870	1.831e-46	180.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CN3J@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
SRR25158351_k127_1100043_56	1229780.BN381_60003	2.768e-31	131.0	COG0357@1|root,COG0357@2|Bacteria	2|Bacteria	J	rRNA methyltransferase activity	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158351_k127_1100043_20	1121877.JQKF01000017_gene197	1.219e-100	354.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CMSR@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158351_k127_1100043_25	1313172.YM304_42840	3.751e-90	305.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CMXK@84992|Acidimicrobiia	84992|Acidimicrobiia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158351_k127_1100043_47	525909.Afer_0032	4.599e-39	160.0	COG3409@1|root,COG3409@2|Bacteria,2HG9Y@201174|Actinobacteria,4CN8M@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Putative peptidoglycan binding domain	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	PG_binding_1
SRR25158351_k127_1100043_51	526225.Gobs_5085	8.406e-37	152.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4ET42@85013|Frankiales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158351_k127_1100043_15	1120936.KB907218_gene3444	7.842e-126	412.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4EGF8@85012|Streptosporangiales	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158351_k127_1100043_46	1313172.YM304_42760	1.733e-39	166.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1100043_33	264732.Moth_0912	1.854e-73	267.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_1100043_29	1313172.YM304_42740	3.743e-80	276.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CN2K@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158351_k127_1100043_19	1229780.BN381_10210	2.643e-106	365.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,3UWJN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	MviN-like protein	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158351_k127_1100043_78	1298860.AUEM01000001_gene1498	1.839e-05	58.0	COG1361@1|root,COG1361@2|Bacteria,2I9F2@201174|Actinobacteria,4FKAY@85023|Microbacteriaceae	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_59	1313172.YM304_42720	1.013e-28	134.0	COG0454@1|root,COG0456@2|Bacteria,2HGG5@201174|Actinobacteria,4CNDG@84992|Acidimicrobiia	84992|Acidimicrobiia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1100043_26	1313172.YM304_28170	3.182e-88	315.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CMXH@84992|Acidimicrobiia	84992|Acidimicrobiia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158351_k127_1100043_17	1229780.BN381_410018	9.122e-116	392.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,3UWHD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158351_k127_1100043_66	1229780.BN381_410019	8.68e-18	99.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158351_k127_1100043_12	1463917.JODC01000009_gene8772	6.714e-153	505.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158351_k127_1100043_74	410359.Pcal_1158	7.066e-07	61.0	arCOG03119@1|root,arCOG03119@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158351_k127_1100043_58	329726.AM1_0713	1.166e-29	134.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158351_k127_1100043_6	1121877.JQKF01000017_gene209	2.059e-180	575.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CNE8@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158351_k127_1100043_57	446462.Amir_7032	1.656e-30	131.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,4E1NG@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158351_k127_1100043_61	994479.GL877880_gene3928	8.635e-28	120.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria,4E3ED@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR25158351_k127_1100043_23	1229780.BN381_100144	2.645e-97	332.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,3UW6F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158351_k127_1100043_69	1313172.YM304_42660	1.013e-10	69.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158351_k127_1100043_64	1229780.BN381_100143	3.659e-24	107.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,3UWQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158351_k127_1100043_41	1229780.BN381_100142	7.433e-49	185.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_1100043_65	1229780.BN381_100141	1.679e-22	110.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,3UWV6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158351_k127_1100043_53	1089553.Tph_c00780	2.742e-34	146.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,42GRT@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158351_k127_1100043_10	1229780.BN381_100139	2.236e-155	505.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,3UW95@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158351_k127_1100043_5	68170.KL590535_gene3741	9.987e-191	605.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4E527@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
SRR25158351_k127_1100043_50	1906.SFRA_26795	1.936e-37	150.0	COG2920@1|root,COG2920@2|Bacteria,2IQB2@201174|Actinobacteria	201174|Actinobacteria	P	PFAM DsrC family protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
SRR25158351_k127_1100043_28	68170.KL590535_gene3743	5.592e-81	277.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EABZ@85010|Pseudonocardiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158351_k127_1100043_34	1463856.JOHY01000039_gene1637	4.151e-72	248.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria	201174|Actinobacteria	L	Glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158351_k127_1100043_31	66429.JOFL01000017_gene358	2.038e-77	269.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158351_k127_1100043_81	1229780.BN381_290145	0.0006794	49.0	2FDCI@1|root,345EC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_14	1313172.YM304_03270	2.42e-130	436.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CNI4@84992|Acidimicrobiia	84992|Acidimicrobiia	JKL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158351_k127_1100043_55	1156844.KB891804_gene2219	1.863e-32	137.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158351_k127_1100043_30	1077144.AGFF01000014_gene3003	5.5e-80	271.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158351_k127_1100043_37	1206744.BAGL01000052_gene2307	1.628e-58	220.0	COG1846@1|root,COG1846@2|Bacteria,2I3U4@201174|Actinobacteria,4FTZA@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_22	1229780.BN381_240007	3.682e-99	339.0	COG0683@1|root,COG0683@2|Bacteria,2GP8K@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_1100043_7	1229780.BN381_240008	6.113e-170	560.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158351_k127_1100043_8	1229780.BN381_100070	1.606e-163	527.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	2|Bacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
SRR25158351_k127_1100043_36	298655.KI912267_gene7716	1.324e-58	219.0	COG0410@1|root,COG0410@2|Bacteria,2IG51@201174|Actinobacteria	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158351_k127_1100043_27	1283299.AUKG01000002_gene4499	7.62e-82	282.0	COG0411@1|root,COG0411@2|Bacteria,2HFVW@201174|Actinobacteria,4CSK2@84995|Rubrobacteria	84995|Rubrobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1100043_1	1313172.YM304_39270	0.0	1047.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158351_k127_1100043_52	1229780.BN381_60087	1.543e-34	136.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HTH_Crp_2,cNMP_binding
SRR25158351_k127_1100043_3	457429.ABJI02000708_gene4282	1.41e-256	809.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158351_k127_1100043_62	1111479.AXAR01000023_gene2906	9.851e-28	121.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,278G9@186823|Alicyclobacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158351_k127_1100043_18	1050202.KB913024_gene3533	1.839e-107	365.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,407VJ@622450|Actinopolysporales	201174|Actinobacteria	O	DnaJ central domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_1100043_60	1229780.BN381_150053	1.443e-28	120.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,3UWU5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158351_k127_1100043_79	1172180.KB911785_gene271	2.567e-05	56.0	2EAJ3@1|root,334N1@2|Bacteria,2GKGE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510
SRR25158351_k127_1100043_0	1278073.MYSTI_05578	0.0	1051.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YUBF@29|Myxococcales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158351_k127_1100043_39	929712.KI912613_gene2041	2.485e-50	194.0	28ND6@1|root,2ZBG0@2|Bacteria,2H5QC@201174|Actinobacteria,4CPT0@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1100043_11	1463934.JOCF01000038_gene2233	3.639e-154	501.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158351_k127_1100043_16	1229780.BN381_130009	4.158e-125	413.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,3UW9D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158351_k127_1100043_45	1313172.YM304_38920	1.084e-42	166.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4CMWU@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158351_k127_1108222_52	1120936.KB907218_gene3297	8.322e-07	52.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,4EMC8@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1108222_39	483219.LILAB_13915	1.213e-28	125.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42UEE@68525|delta/epsilon subdivisions,2WQHS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158351_k127_1108222_5	525909.Afer_0459	2.839e-191	604.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158351_k127_1108222_3	264732.Moth_2105	1.384e-209	672.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,42EXT@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158351_k127_1108222_17	292415.Tbd_1513	2.72e-127	438.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2VMRG@28216|Betaproteobacteria,1KSP0@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Fructose-bisphosphate aldolase class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR25158351_k127_1108222_33	1380390.JIAT01000010_gene3900	8.125e-43	177.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4CP8B@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158351_k127_1108222_28	1313172.YM304_25490	2.454e-72	256.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158351_k127_1108222_1	1229780.BN381_130048	1.014e-222	732.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,3UWC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158351_k127_1108222_8	1229780.BN381_130057	2.808e-171	545.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,3UWCT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158351_k127_1108222_14	1229780.BN381_130058	3.838e-147	470.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,3UWCZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158351_k127_1108222_50	1386089.N865_01325	5.591e-08	64.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4FEN1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158351_k127_1108222_31	1229780.BN381_130059	2.338e-52	200.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,3UWRP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158351_k127_1108222_11	649638.Trad_0076	1.241e-165	541.0	COG0138@1|root,COG0138@2|Bacteria,1WIVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158351_k127_1108222_22	338963.Pcar_2461	9.739e-102	339.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158351_k127_1108222_4	1121877.JQKF01000035_gene1958	4.415e-204	640.0	COG0538@1|root,COG0538@2|Bacteria,2IBM8@201174|Actinobacteria,4CNHG@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_1108222_42	1229780.BN381_10056	1.301e-23	111.0	COG2214@1|root,COG2214@2|Bacteria,2H5PV@201174|Actinobacteria	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1108222_16	1120950.KB892812_gene6966	2.26e-134	435.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DN1I@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158351_k127_1108222_40	405948.SACE_2073	1.259e-25	123.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4EC4R@85010|Pseudonocardiales	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158351_k127_1108222_27	1229780.BN381_10209	8.19e-76	271.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158351_k127_1108222_36	1229780.BN381_10211	4.836e-39	156.0	2CIFA@1|root,348QY@2|Bacteria,2H88E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1108222_7	1229780.BN381_10212	3.05e-175	588.0	COG2304@1|root,COG2304@2|Bacteria,2HQ9B@201174|Actinobacteria,3UXG6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
SRR25158351_k127_1108222_51	1278073.MYSTI_06457	7.519e-08	66.0	COG1840@1|root,COG1840@2|Bacteria,1QX5Y@1224|Proteobacteria,42PKC@68525|delta/epsilon subdivisions,2WISI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
SRR25158351_k127_1108222_20	1229780.BN381_10215	1.513e-108	368.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria	201174|Actinobacteria	O	AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158351_k127_1108222_35	234621.RER_11400	1.502e-40	162.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4G8JQ@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_1108222_45	1229780.BN381_130073	1.199e-16	93.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
SRR25158351_k127_1108222_38	1324957.K933_14713	5.347e-37	144.0	COG2258@1|root,arCOG11383@2157|Archaea,2XXK8@28890|Euryarchaeota,23VKF@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158351_k127_1108222_18	1440774.Y900_025975	3.584e-126	417.0	2DB85@1|root,2Z7Q2@2|Bacteria,2GTBY@201174|Actinobacteria,2332E@1762|Mycobacteriaceae	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158351_k127_1108222_13	1313172.YM304_19020	3.984e-156	506.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CMTY@84992|Acidimicrobiia	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158351_k127_1108222_9	1229780.BN381_170035	3.927e-167	542.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158351_k127_1108222_6	1229780.BN381_170034	2.545e-177	572.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,3UWFB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158351_k127_1108222_2	234267.Acid_3687	5.133e-216	696.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158351_k127_1108222_29	1121877.JQKF01000001_gene1338	7.103e-71	251.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158351_k127_1108222_41	31964.CMS0722	2.077e-25	119.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria,4FQF3@85023|Microbacteriaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158351_k127_1108222_10	1229780.BN381_300001	2.807e-166	559.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158351_k127_1108222_15	450851.PHZ_c2065	1.885e-134	447.0	COG0318@1|root,COG0318@2|Bacteria,1MVJ1@1224|Proteobacteria,2TUQ9@28211|Alphaproteobacteria,2KIBE@204458|Caulobacterales	204458|Caulobacterales	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1108222_26	479435.Kfla_0094	3.131e-78	272.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4DPT2@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158351_k127_1108222_44	1121924.ATWH01000003_gene1594	1.202e-17	93.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4FRGN@85023|Microbacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158351_k127_1108222_25	1229780.BN381_100200	2.766e-80	283.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria,3UXBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158351_k127_1108222_30	1229780.BN381_60078	1.802e-56	211.0	COG0204@1|root,COG0204@2|Bacteria,2I8I4@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158351_k127_1108222_12	298654.FraEuI1c_4779	1.125e-163	527.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria	201174|Actinobacteria	I	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1108222_47	1157490.EL26_21775	1.004e-10	72.0	COG0860@1|root,COG0860@2|Bacteria,1TWQM@1239|Firmicutes,4HC00@91061|Bacilli	91061|Bacilli	M	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Glucosaminidase,SPOR
SRR25158351_k127_1108222_53	1297617.JPJD01000049_gene1326	1.867e-06	59.0	COG0860@1|root,COG0860@2|Bacteria,1UVPV@1239|Firmicutes,25KKI@186801|Clostridia,26BCN@186813|unclassified Clostridiales	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
SRR25158351_k127_1108222_43	218284.CCDN010000005_gene3340	2.533e-21	105.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus	91061|Bacilli	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158351_k127_1108222_46	118161.KB235922_gene1057	6.021e-15	82.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,3VJV5@52604|Pleurocapsales	1117|Cyanobacteria	KT	COGs COG0317 Guanosine polyphosphate pyrophosphohydrolase synthetase	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
SRR25158351_k127_1108222_19	1394178.AWOO02000023_gene5429	1.704e-109	363.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EHHD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1108222_0	469383.Cwoe_2006	2.118e-300	937.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_1108222_34	1229780.BN381_10085	1.082e-42	179.0	COG1011@1|root,COG1011@2|Bacteria,2HP8I@201174|Actinobacteria,3UWYW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158351_k127_1108222_23	1380346.JNIH01000027_gene5812	1.57e-91	318.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158351_k127_1108222_21	1283283.ATXA01000021_gene2882	2.833e-105	366.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_1108222_24	1380394.JADL01000013_gene577	4.563e-83	286.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K22303	-	-	-	-	ko00000,ko01000	-	-	-	TauD
SRR25158351_k127_1108222_37	298654.FraEuI1c_3878	1.669e-37	154.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1108222_32	1463917.JODC01000010_gene4209	5.814e-50	185.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158351_k127_1119078_12	765911.Thivi_2917	1.79e-12	76.0	COG0560@1|root,COG0560@2|Bacteria,1RKIX@1224|Proteobacteria,1S4JE@1236|Gammaproteobacteria,1X26W@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_1119078_7	1463936.JOJI01000013_gene4686	6.877e-87	299.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
SRR25158351_k127_1119078_1	436229.JOEH01000041_gene6328	2.697e-174	566.0	COG0277@1|root,COG0277@2|Bacteria,2HH8C@201174|Actinobacteria,2NGT9@228398|Streptacidiphilus	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
SRR25158351_k127_1119078_8	1211815.CBYP010000044_gene393	7.4e-81	284.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4EV3I@85013|Frankiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016763,GO:0031224,GO:0031226,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046872,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.2.45	ko:K14136	-	-	R10095	RC00005	ko00000,ko01000,ko01006	-	-	-	UbiA
SRR25158351_k127_1119078_9	1229780.BN381_80027	2.119e-47	179.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,3UWVY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158351_k127_1119078_3	1229780.BN381_80028	5.583e-118	398.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,3UWAR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158351_k127_1119078_13	192952.MM_2343	4.993e-10	72.0	COG3794@1|root,arCOG02929@2157|Archaea,2Y1NH@28890|Euryarchaeota,2NB8Y@224756|Methanomicrobia	224756|Methanomicrobia	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158351_k127_1119078_6	1229780.BN381_80366	3.57e-87	310.0	COG4677@1|root,COG4677@2|Bacteria,2I7VB@201174|Actinobacteria	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158351_k127_1119078_2	525909.Afer_0728	1.052e-171	550.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
SRR25158351_k127_1119078_5	1211815.CBYP010000069_gene1348	2.066e-90	304.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158351_k127_1119078_11	1313172.YM304_29090	1.828e-32	139.0	2BJWW@1|root,32E9A@2|Bacteria,2HGG7@201174|Actinobacteria,4CNDN@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1119078_4	1282876.BAOK01000002_gene776	9.069e-113	375.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,4BPNJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158351_k127_1119078_0	1244869.H261_08693	0.0	1074.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158351_k127_1119078_10	1108045.GORHZ_030_00030	1.826e-44	185.0	COG5479@1|root,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4GB5A@85026|Gordoniaceae	201174|Actinobacteria	M	Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme.	csp	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
SRR25158351_k127_1121872_34	1380347.JNII01000005_gene3705	8.394e-24	104.0	2FCGD@1|root,344JU@2|Bacteria,2IRV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1121872_24	166318.Syn8016DRAFT_0646	1.159e-48	186.0	COG5031@1|root,COG5031@2|Bacteria,1GQ8D@1117|Cyanobacteria,1H069@1129|Synechococcus	1117|Cyanobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1121872_35	1380393.JHVP01000004_gene401	2.625e-22	99.0	COG5416@1|root,COG5416@2|Bacteria,2HD5K@201174|Actinobacteria	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR25158351_k127_1121872_31	44056.XP_009034843.1	1.411e-29	137.0	2DE90@1|root,2S5PQ@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1121872_28	402777.KB235903_gene1612	1.074e-35	156.0	COG3751@1|root,COG3751@2|Bacteria,1G31S@1117|Cyanobacteria,1H9W0@1150|Oscillatoriales	1117|Cyanobacteria	O	SMART Prolyl 4-hydroxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
SRR25158351_k127_1121872_42	1198114.AciX9_2169	5.217e-09	64.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158351_k127_1121872_25	565045.NOR51B_1280	5.644e-41	165.0	2DW20@1|root,32V0K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1121872_19	565045.NOR51B_2417	1.213e-65	250.0	COG1215@1|root,COG1215@2|Bacteria,1R0YM@1224|Proteobacteria,1T4RQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase (GlcNAc)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc
SRR25158351_k127_1121872_39	242159.ABO94183	1.401e-16	91.0	2CMIY@1|root,2QQG8@2759|Eukaryota,37HXX@33090|Viridiplantae,34I01@3041|Chlorophyta	3041|Chlorophyta	-	-	-	-	-	ko:K20781	ko00514,map00514	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT96	-	ShK
SRR25158351_k127_1121872_1	525368.HMPREF0591_2108	2.16e-159	507.0	28MHV@1|root,2ZAUP@2|Bacteria,2IA17@201174|Actinobacteria,23835@1762|Mycobacteriaceae	201174|Actinobacteria	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
SRR25158351_k127_1121872_32	1464048.JNZS01000032_gene2863	1.944e-28	122.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria,4DD92@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_1121872_3	1108045.GORHZ_118_00340	3.316e-154	494.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158351_k127_1121872_33	1040989.AWZU01000023_gene4843	7.76e-27	116.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158351_k127_1121872_21	710685.MycrhN_1776	1.513e-62	232.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158351_k127_1121872_27	1122239.AULS01000001_gene1779	4.082e-36	151.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FN7T@85023|Microbacteriaceae	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_1121872_22	1313172.YM304_27100	8.832e-55	201.0	2BZNP@1|root,30717@2|Bacteria,2IAEK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
SRR25158351_k127_1121872_10	648757.Rvan_3533	4.419e-84	302.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158351_k127_1121872_16	1385521.N803_14125	6.437e-78	269.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria	201174|Actinobacteria	C	pyridoxamine 5-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158351_k127_1121872_11	42256.RradSPS_0559	2.369e-82	293.0	COG0477@1|root,COG2814@2|Bacteria,2IFXN@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1121872_18	1123258.AQXZ01000019_gene2903	1.668e-69	237.0	COG3651@1|root,COG3651@2|Bacteria,2IHNI@201174|Actinobacteria,4G0HJ@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
SRR25158351_k127_1121872_20	222534.KB893762_gene3599	1.283e-65	254.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,2GQF8@201174|Actinobacteria,4EUTN@85013|Frankiales	201174|Actinobacteria	Q	synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
SRR25158351_k127_1121872_41	446469.Sked_30520	3.128e-11	78.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1121872_40	1274524.BSONL12_03069	2.124e-12	77.0	COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1ZCIE@1386|Bacillus	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	yhdW	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158351_k127_1121872_9	1229780.BN381_310018	5.303e-90	308.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259,ko:K19311	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158351_k127_1121872_7	1041522.MCOL_V219131	1.811e-105	358.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,23579@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158351_k127_1121872_38	1397278.AYMV01000007_gene257	5.975e-17	92.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4FTTD@85023|Microbacteriaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158351_k127_1121872_12	1229780.BN381_10309	5.13e-82	285.0	COG1131@1|root,COG1131@2|Bacteria,2HEWT@201174|Actinobacteria,3UXA3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158351_k127_1121872_36	345341.KUTG_00465	2.65e-20	93.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR25158351_k127_1121872_2	1283283.ATXA01000009_gene3261	1.114e-158	514.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1121872_5	1160137.KB907307_gene2936	2.057e-116	386.0	COG2267@1|root,COG2267@2|Bacteria,2I5VV@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_1121872_26	309801.trd_A0805	1.479e-38	153.0	COG1525@1|root,COG1525@2|Bacteria,2GB5G@200795|Chloroflexi,27Z81@189775|Thermomicrobia	189775|Thermomicrobia	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158351_k127_1121872_4	35754.JNYJ01000001_gene7046	1.486e-141	460.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4D93W@85008|Micromonosporales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_1121872_23	1282876.BAOK01000002_gene511	1.29e-50	184.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2U9AT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	MA20_19855	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158351_k127_1121872_37	1173027.Mic7113_5587	7.797e-19	94.0	COG2732@1|root,COG2732@2|Bacteria,1G9I5@1117|Cyanobacteria,1HDDH@1150|Oscillatoriales	1117|Cyanobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
SRR25158351_k127_1121872_29	1385519.N801_13310	3.27e-34	148.0	COG4290@1|root,COG4290@2|Bacteria,2IHPV@201174|Actinobacteria,4FHBV@85021|Intrasporangiaceae	201174|Actinobacteria	F	ribonuclease	-	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
SRR25158351_k127_1121872_14	1370121.AUWS01000035_gene4499	5.143e-79	291.0	COG0604@1|root,COG0604@2|Bacteria,2IATU@201174|Actinobacteria,237C7@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1121872_8	1348657.M622_05025	1.505e-95	327.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158351_k127_1121872_30	1330700.JQNC01000003_gene665	5.448e-30	126.0	COG2402@1|root,COG2402@2|Bacteria,1WJXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158351_k127_1121872_43	1123388.AQWU01000052_gene1624	3.312e-06	54.0	2DSVR@1|root,33HKS@2|Bacteria,1WKIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
SRR25158351_k127_1121872_6	222534.KB893671_gene3356	2.105e-109	370.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4ES53@85013|Frankiales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158351_k127_1121872_15	330084.JNYZ01000050_gene8634	5.706e-78	267.0	COG3917@1|root,COG3917@2|Bacteria,2I8XT@201174|Actinobacteria,4DZI0@85010|Pseudonocardiales	201174|Actinobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1121872_13	1306174.JODP01000002_gene5732	4.927e-80	278.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbB	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158351_k127_1121872_0	557599.MKAN_07990	4.66e-203	642.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,23361@1762|Mycobacteriaceae	201174|Actinobacteria	P	flavoprotein involved in K transport	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
SRR25158351_k127_1121872_17	1123240.ATVO01000009_gene737	4.028e-72	257.0	2C8FR@1|root,34BJJ@2|Bacteria,1P3IC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1149703_24	91464.S7335_3793	2.002e-18	95.0	2DP18@1|root,33041@2|Bacteria,1GQIX@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
SRR25158351_k127_1149703_21	1313172.YM304_31100	2.089e-32	139.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158351_k127_1149703_26	644548.SCNU_08273	1.303e-15	82.0	2B381@1|root,31VW2@2|Bacteria,2HX88@201174|Actinobacteria,4GETV@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1149703_20	1121877.JQKF01000024_gene2385	6.547e-40	153.0	COG0764@1|root,COG0764@2|Bacteria,2GQWT@201174|Actinobacteria,4CN5K@84992|Acidimicrobiia	84992|Acidimicrobiia	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158351_k127_1149703_12	1463854.JOHT01000007_gene3386	2.276e-74	261.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Acyl transferase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158351_k127_1149703_27	1121877.JQKF01000021_gene2197	8.663e-10	64.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158351_k127_1149703_7	477974.Daud_0639	2.014e-104	352.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158351_k127_1149703_11	1463854.JOHT01000007_gene3385	2.075e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria	1463854.JOHT01000007_gene3385|-	IQ	reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1149703_25	1313172.YM304_21310	3.471e-18	87.0	COG0236@1|root,COG0236@2|Bacteria,2HGA0@201174|Actinobacteria,4CN8U@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158351_k127_1149703_5	909613.UO65_3371	5.764e-116	390.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_1149703_3	1313172.YM304_21250	3.922e-132	436.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMQK@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158351_k127_1149703_6	1304865.JAGF01000001_gene3623	3.995e-112	366.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4F0ZV@85016|Cellulomonadaceae	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208,ko:K11611	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1149703_23	1229780.BN381_90008	7.369e-22	100.0	COG0664@1|root,COG0664@2|Bacteria,2GYD2@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158351_k127_1149703_16	706587.Desti_1456	2.067e-56	201.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158351_k127_1149703_10	1229780.BN381_350134	1.574e-88	299.0	COG0412@1|root,COG0412@2|Bacteria,2GK7H@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158351_k127_1149703_9	1313172.YM304_24320	1.377e-88	300.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CMZW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158351_k127_1149703_2	1246995.AFR_20260	7.285e-158	515.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4D9BB@85008|Micromonosporales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_1149703_13	1313172.YM304_24300	1.456e-60	222.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CN2A@84992|Acidimicrobiia	84992|Acidimicrobiia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158351_k127_1149703_17	469383.Cwoe_5537	7.639e-50	198.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria	201174|Actinobacteria	I	Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158351_k127_1149703_8	1123023.JIAI01000019_gene2183	8.9e-98	338.0	COG1024@1|root,COG1024@2|Bacteria,2I9DY@201174|Actinobacteria	201174|Actinobacteria	I	enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1149703_15	1292034.OR37_00184	2.18e-59	226.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,2KFCQ@204458|Caulobacterales	204458|Caulobacterales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158351_k127_1149703_4	324602.Caur_0360	8.103e-128	422.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi,3774T@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158351_k127_1149703_18	929712.KI912613_gene3241	3.906e-45	176.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_1149703_1	1229780.BN381_80375	2.894e-170	549.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,3UW9N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Anthranilate synthase component 1	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158351_k127_1149703_19	1313172.YM304_22700	2.593e-40	158.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CN95@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
SRR25158351_k127_1149703_0	512565.AMIS_1760	6.933e-216	693.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4DAD5@85008|Micromonosporales	201174|Actinobacteria	E	Oligopeptidase b	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158351_k127_1149703_14	1380390.JIAT01000011_gene2844	3.013e-60	218.0	COG2050@1|root,COG2050@2|Bacteria,2HPRC@201174|Actinobacteria,4CR4I@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158351_k127_1149703_22	1121430.JMLG01000026_gene2	5.006e-25	115.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	QU41_16170	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S15
SRR25158351_k127_1185844_5	525909.Afer_0231	9.44e-136	436.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMPB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158351_k127_1185844_16	1313172.YM304_37240	4.751e-74	262.0	COG1409@1|root,COG1409@2|Bacteria,2IDNH@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
SRR25158351_k127_1185844_6	1313172.YM304_02580	2.01e-131	430.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158351_k127_1185844_2	1229780.BN381_70027	3.624e-190	616.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,3UX6T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158351_k127_1185844_0	1449353.JQMQ01000005_gene1513	3.694e-280	875.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,2NGQ7@228398|Streptacidiphilus	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158351_k127_1185844_10	1229780.BN381_100132	5.972e-108	367.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,3UX97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158351_k127_1185844_20	1229780.BN381_100131	1.538e-42	168.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158351_k127_1185844_22	1210046.B277_12456	1.211e-39	169.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4FG3D@85021|Intrasporangiaceae	201174|Actinobacteria	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158351_k127_1185844_4	1121877.JQKF01000011_gene381	1.055e-158	534.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CMX1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158351_k127_1185844_12	561175.KB894093_gene3409	5.025e-97	329.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4EGS7@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
SRR25158351_k127_1185844_26	1229780.BN381_100122	3.667e-18	90.0	COG0745@1|root,COG0745@2|Bacteria	1229780.BN381_100122|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1185844_13	1229780.BN381_100120	2.377e-93	335.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,3UX1R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158351_k127_1185844_15	1229780.BN381_100119	1.646e-82	291.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,3UXHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158351_k127_1185844_17	1313172.YM304_38190	2.586e-60	237.0	COG1030@1|root,COG1030@2|Bacteria,2IATM@201174|Actinobacteria	201174|Actinobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158351_k127_1185844_25	1229780.BN381_100117	2.872e-23	102.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158351_k127_1185844_7	1313172.YM304_38210	8.941e-126	449.0	COG3276@1|root,COG3276@2|Bacteria,2I7V8@201174|Actinobacteria	201174|Actinobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,SelB-wing_3
SRR25158351_k127_1185844_11	324602.Caur_1021	2.746e-106	363.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi,376BM@32061|Chloroflexia	32061|Chloroflexia	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158351_k127_1185844_21	1121877.JQKF01000018_gene2547	3.104e-40	160.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4CN1R@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1185844_18	314266.SKA58_14137	2.884e-59	222.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2K18T@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_1185844_9	1313172.YM304_38460	6.281e-123	407.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2H1YI@201174|Actinobacteria,4CNPI@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158351_k127_1185844_19	1313172.YM304_38450	3.736e-49	194.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158351_k127_1185844_23	525909.Afer_0240	1.775e-32	130.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CN53@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Iron-sulphur cluster biosynthesis	erpA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158351_k127_1185844_24	469383.Cwoe_4202	1.472e-30	133.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1185844_8	1313172.YM304_38400	4.158e-124	421.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	xdh	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158351_k127_1185844_27	994479.GL877879_gene5873	4.779e-12	76.0	2CG61@1|root,33W7P@2|Bacteria,2IRYJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1185844_14	1313172.YM304_38350	4.513e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CN27@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158351_k127_1185844_3	1313172.YM304_38340	7.308e-184	585.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CMV7@84992|Acidimicrobiia	84992|Acidimicrobiia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158351_k127_1185844_1	1043493.BBLU01000002_gene1600	5.713e-215	676.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158351_k127_1201273_17	222534.KB893717_gene2176	3.667e-32	137.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
SRR25158351_k127_1201273_12	1437882.AZRU01000035_gene352	5.19e-82	289.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,1RZUZ@1236|Gammaproteobacteria,1YFR6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	Beta-lactamase	estC	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_1201273_0	1184607.AUCHE_05_04270	0.0	1457.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158351_k127_1201273_10	867845.KI911784_gene1685	2.714e-96	340.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158351_k127_1201273_24	446468.Ndas_1111	2.346e-13	76.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJD9@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_1201273_18	408672.NBCG_00751	1.132e-21	106.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158351_k127_1201273_20	1294273.roselon_00535	8.48e-19	91.0	COG1637@1|root,COG1637@2|Bacteria,1R9EG@1224|Proteobacteria,2TZPC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
SRR25158351_k127_1201273_9	1337936.IJ00_06170	7.597e-103	350.0	COG3287@1|root,COG3287@2|Bacteria,1G0HF@1117|Cyanobacteria,1HRS0@1161|Nostocales	1117|Cyanobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158351_k127_1201273_8	1121447.JONL01000001_gene930	1.471e-106	357.0	COG2114@1|root,COG3829@1|root,COG2114@2|Bacteria,COG3829@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3365,Guanylate_cyc,MASE2
SRR25158351_k127_1201273_7	56780.SYN_00391	8.721e-112	368.0	COG1879@1|root,COG1879@2|Bacteria,1R8FV@1224|Proteobacteria	1224|Proteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158351_k127_1201273_23	1416759.AYMR01000018_gene2181	1.126e-13	71.0	COG3583@1|root,COG3583@2|Bacteria,2GRTZ@201174|Actinobacteria,4FPYF@85023|Microbacteriaceae	201174|Actinobacteria	S	G5	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,G5
SRR25158351_k127_1201273_3	1380356.JNIK01000015_gene2311	8.545e-163	543.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1201273_13	1380386.JIAW01000012_gene1800	3.906e-66	236.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,23582@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1201273_22	312284.A20C1_07823	1.744e-14	81.0	COG2247@1|root,COG2340@1|root,COG2247@2|Bacteria,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CW_binding_2,CarboxypepD_reg,HemolysinCabind
SRR25158351_k127_1201273_15	1123320.KB889697_gene9016	2.686e-63	231.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158351_k127_1201273_1	134676.ACPL_7782	7.757e-197	620.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4DAUT@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158351_k127_1201273_4	1068980.ARVW01000001_gene524	1.107e-149	478.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4DXTN@85010|Pseudonocardiales	201174|Actinobacteria	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158351_k127_1201273_14	350058.Mvan_0907	9.053e-64	233.0	COG2159@1|root,COG2159@2|Bacteria,2H2CJ@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1201273_6	1123320.KB889662_gene1681	1.805e-131	432.0	2BYTM@1|root,2ZA70@2|Bacteria,2I87B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1201273_21	1370121.AUWS01000004_gene3407	4.944e-18	98.0	COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,232YT@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ion transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158351_k127_1201273_19	358823.DF19_02645	2.222e-19	99.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_1201273_16	1089544.KB912942_gene1813	2.91e-47	180.0	COG1018@1|root,COG4097@1|root,COG1018@2|Bacteria,COG4097@2|Bacteria,2GKGS@201174|Actinobacteria	2|Bacteria	C	Oxidoreductase FAD-binding domain	paaE	GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	1.18.1.3	ko:K00529,ko:K02613	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783,R09838	RC00098,RC02690	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A1479	FAD_binding_6,Fer2,NAD_binding_1
SRR25158351_k127_1201273_11	298655.KI912266_gene2834	7.277e-90	301.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1201273_5	298655.KI912266_gene2835	2.636e-141	487.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2ICGU@201174|Actinobacteria	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158351_k127_1201273_2	298655.KI912266_gene5581	1.515e-167	536.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1291408_22	1298880.AUEV01000020_gene593	4.734e-07	52.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158351_k127_1291408_13	1229780.BN381_150047	1.658e-56	200.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,3UWVQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158351_k127_1291408_2	1313172.YM304_37120	2.089e-206	653.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CMSB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Zinc-binding dehydrogenase	-	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1291408_4	1121877.JQKF01000011_gene378	5.411e-168	537.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTP@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1291408_21	408672.NBCG_04891	2.709e-09	63.0	2EGD2@1|root,33A4V@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158351_k127_1291408_24	1713.JOFV01000008_gene3224	1.923e-05	57.0	COG5473@1|root,COG5473@2|Bacteria,2GN5K@201174|Actinobacteria,4F1IF@85016|Cellulomonadaceae	201174|Actinobacteria	J	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1291408_15	1380356.JNIK01000017_gene2921	1.782e-35	142.0	2DK6R@1|root,32UEG@2|Bacteria,2INPY@201174|Actinobacteria,4EW57@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158351_k127_1291408_1	298654.FraEuI1c_4697	7.347e-208	663.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4ES02@85013|Frankiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3340	Cys_Met_Meta_PP
SRR25158351_k127_1291408_6	645465.ACUR01000585_gene3507	8.995e-141	457.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158351_k127_1291408_9	33898.JRHJ01000001_gene643	4.063e-89	297.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158351_k127_1291408_17	1321784.HMPREF1987_01333	2.159e-23	109.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,25RIG@186804|Peptostreptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158351_k127_1291408_10	2045.KR76_02755	6.72e-87	314.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4DP04@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158351_k127_1291408_14	1463855.JOHV01000016_gene843	1.488e-43	166.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158351_k127_1291408_11	1313172.YM304_07250	2.085e-82	283.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CN4K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158351_k127_1291408_0	1463900.JOIX01000017_gene2380	7.575e-247	783.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158351_k127_1291408_16	471857.Svir_36760	2.316e-28	120.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4E5MK@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158351_k127_1291408_18	882083.SacmaDRAFT_0433	2.229e-19	96.0	COG0515@1|root,COG0515@2|Bacteria,2IKPQ@201174|Actinobacteria,4E6JV@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
SRR25158351_k127_1291408_5	1229780.BN381_310078	4.653e-165	534.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158351_k127_1291408_7	1122939.ATUD01000006_gene1753	6.579e-106	372.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CPMJ@84995|Rubrobacteria	84995|Rubrobacteria	OP	Na+/H+ antiporter 1	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158351_k127_1291408_23	1123508.JH636441_gene3082	1.116e-05	57.0	COG0745@1|root,COG0745@2|Bacteria,2J1NZ@203682|Planctomycetes	203682|Planctomycetes	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1291408_3	1229780.BN381_10241	2.221e-172	561.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	pks16	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	6.2.1.20	ko:K00666,ko:K01909	ko00071,map00071	-	R01406	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AMP-binding_C_2
SRR25158351_k127_1291408_8	1003195.SCAT_4681	3.68e-94	329.0	COG1807@1|root,COG1807@2|Bacteria,2GP96@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158351_k127_1291408_12	1128421.JAGA01000003_gene3532	1.295e-67	240.0	COG5032@1|root,COG5032@2|Bacteria,2NR1S@2323|unclassified Bacteria	2|Bacteria	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
SRR25158351_k127_1291408_19	512565.AMIS_53930	1.139e-15	81.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4D9TX@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158351_k127_1343850_2	649747.HMPREF0083_03424	5.171e-123	411.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26R9D@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158351_k127_1343850_3	337191.KTR9_0277	1.658e-38	156.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4GDST@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR25158351_k127_1343850_1	1313172.YM304_26780	5.428e-193	612.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158351_k127_1343850_0	1380347.JNII01000007_gene557	0.0	1281.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4ES2Q@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158351_k127_1345801_6	446462.Amir_3552	3.214e-25	114.0	COG0596@1|root,COG0596@2|Bacteria,2I51U@201174|Actinobacteria,4E7Q6@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_1345801_3	1123320.KB889669_gene3266	9.579e-58	205.0	2DBEE@1|root,2Z8S9@2|Bacteria,2ISRT@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_1345801_7	1122622.ATWJ01000010_gene1263	9.793e-06	48.0	COG0028@1|root,COG3291@1|root,COG0028@2|Bacteria,COG3291@2|Bacteria,2I5PU@201174|Actinobacteria	201174|Actinobacteria	M	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36
SRR25158351_k127_1345801_1	1464048.JNZS01000037_gene4717	5.351e-96	334.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4D90U@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158351_k127_1345801_0	1041522.MCOL_V202830	5.963e-151	511.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,235AT@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1345801_2	710686.Mycsm_03169	1.066e-67	244.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_1345801_4	1123320.KB889687_gene894	2.367e-37	148.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158351_k127_1345801_5	395961.Cyan7425_1963	3.443e-34	140.0	COG1028@1|root,COG1028@2|Bacteria,1G2ZD@1117|Cyanobacteria,3KJXW@43988|Cyanothece	1117|Cyanobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1365144_52	1229780.BN381_50173	6.591e-31	127.0	2F9Q3@1|root,34209@2|Bacteria,2H616@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1365144_42	269800.Tfu_2105	6.471e-49	181.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4EIC7@85012|Streptosporangiales	201174|Actinobacteria	FG	Protein similar to CwfJ C-terminus 1	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158351_k127_1365144_3	471852.Tcur_2095	6.353e-235	744.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4EG5V@85012|Streptosporangiales	201174|Actinobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158351_k127_1365144_10	1229780.BN381_50169	6.012e-136	447.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,3UX20@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
SRR25158351_k127_1365144_40	1229780.BN381_50168	7.712e-53	195.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158351_k127_1365144_0	1313172.YM304_19620	0.0	1347.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CMWT@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158351_k127_1365144_27	1313172.YM304_19600	7.205e-81	297.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4CMXF@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158351_k127_1365144_46	1229780.BN381_430076	1.475e-39	165.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158351_k127_1365144_30	1229780.BN381_430078	4.05e-79	282.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,3UWB2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158351_k127_1365144_55	1172185.KB911510_gene1322	2.079e-29	128.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4G0PW@85025|Nocardiaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158351_k127_1365144_57	1229780.BN381_430080	4.686e-26	119.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158351_k127_1365144_1	1283299.AUKG01000001_gene1954	1e-323	1023.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158351_k127_1365144_68	1121877.JQKF01000014_gene18	4.936e-07	61.0	COG3599@1|root,COG3599@2|Bacteria,2HGXW@201174|Actinobacteria,4CNY1@84992|Acidimicrobiia	84992|Acidimicrobiia	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158351_k127_1365144_56	1229780.BN381_140002	7.117e-27	119.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,3UWTH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158351_k127_1365144_48	1054213.HMPREF9946_05175	4.172e-39	159.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2JQKQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158351_k127_1365144_49	1384056.N787_09180	1.715e-36	157.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1X34B@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158351_k127_1365144_7	1313172.YM304_19500	3.931e-155	498.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CMR8@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158351_k127_1365144_64	1313172.YM304_19490	1.107e-10	73.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	6.3.2.4	ko:K01921,ko:K03589,ko:K06438	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158351_k127_1365144_36	1313172.YM304_19480	8.974e-62	232.0	COG0812@1|root,COG0812@2|Bacteria,2HG0Y@201174|Actinobacteria,4CMXR@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158351_k127_1365144_9	1313172.YM304_19470	4.146e-138	458.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CMTG@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1365144_37	1054860.KB913030_gene4640	2.325e-59	233.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158351_k127_1365144_24	1009370.ALO_17371	3.482e-91	314.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4H3RE@909932|Negativicutes	909932|Negativicutes	D	TIGRFAM stage V sporulation protein E, cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_1365144_31	710111.FraQA3DRAFT_2859	8.073e-79	291.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4ERI0@85013|Frankiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1365144_20	525909.Afer_1248	3.184e-98	350.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CMYF@84992|Acidimicrobiia	84992|Acidimicrobiia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158351_k127_1365144_23	1220583.GOACH_04_00030	8.281e-93	321.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4GA43@85026|Gordoniaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1365144_13	351607.Acel_1005	1.322e-117	395.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4ES9W@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1365144_15	351607.Acel_1004	8.898e-114	391.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4ERN7@85013|Frankiales	201174|Actinobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158351_k127_1365144_28	1313172.YM304_19390	7.683e-80	288.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CN25@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158351_k127_1365144_53	930171.Asphe3_15430	2.161e-30	124.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,1W8YH@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158351_k127_1365144_38	1048339.KB913029_gene4935	8.252e-55	197.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4ESID@85013|Frankiales	201174|Actinobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158351_k127_1365144_17	1394178.AWOO02000064_gene80	2.421e-105	352.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria	201174|Actinobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158351_k127_1365144_51	1123322.KB904662_gene4184	5.342e-31	142.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria	201174|Actinobacteria	J	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158351_k127_1365144_41	1229780.BN381_140023	1.959e-50	204.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,3UWTV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158351_k127_1365144_60	1121877.JQKF01000004_gene1087	1.462e-19	95.0	2ERJT@1|root,33J59@2|Bacteria,2HGGQ@201174|Actinobacteria,4CNDW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR25158351_k127_1365144_58	1410620.SHLA_5c000130	6.76e-20	104.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2U1Y7@28211|Alphaproteobacteria,4BA95@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158351_k127_1365144_16	471852.Tcur_2940	3.44e-111	373.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4EH2D@85012|Streptosporangiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158351_k127_1365144_45	1229780.BN381_140026	6.366e-42	159.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	MA20_41050	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158351_k127_1365144_43	1121877.JQKF01000004_gene1089	1.935e-47	179.0	COG2120@1|root,COG2120@2|Bacteria,2HF8J@201174|Actinobacteria,4CNQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_1365144_26	696369.KI912183_gene2321	5.844e-84	293.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,258R8@186801|Clostridia,261A0@186807|Peptococcaceae	186801|Clostridia	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158351_k127_1365144_19	414996.IL38_08545	1.154e-102	344.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,408HM@622450|Actinopolysporales	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158351_k127_1365144_11	1298863.AUEP01000002_gene1491	2.423e-133	437.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DPJ3@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158351_k127_1365144_4	1380356.JNIK01000021_gene4464	2.387e-176	565.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4EREP@85013|Frankiales	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158351_k127_1365144_67	1121017.AUFG01000001_gene2985	4.345e-08	61.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FEIG@85021|Intrasporangiaceae	201174|Actinobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158351_k127_1365144_8	644282.Deba_1381	2.157e-154	496.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1365144_47	1313172.YM304_14110	2.513e-39	157.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158351_k127_1365144_65	1123023.JIAI01000004_gene8150	1.432e-10	73.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,4E4XM@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1365144_34	1048339.KB913029_gene4597	4.437e-68	243.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4ERT7@85013|Frankiales	201174|Actinobacteria	GK	PFAM ROK family protein	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158351_k127_1365144_50	525909.Afer_0938	1.718e-33	140.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4CN9D@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158351_k127_1365144_66	1313172.YM304_19150	9.45e-09	62.0	28Z2K@1|root,2ZKV3@2|Bacteria,2HA4X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1365144_21	1229780.BN381_140042	7.418e-97	341.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,3UXEM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferases group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1365144_32	1122138.AQUZ01000015_gene6845	4.958e-74	267.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4DVK7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158351_k127_1365144_33	1449069.JMLO01000018_gene596	1.106e-70	252.0	COG1024@1|root,COG1024@2|Bacteria,2IP2B@201174|Actinobacteria,4G2VY@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1365144_18	1313172.YM304_02000	2.954e-105	355.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4CN2E@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Reductase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
SRR25158351_k127_1365144_2	1123320.KB889585_gene1915	7.192e-252	799.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158351_k127_1365144_25	1172180.KB911797_gene8035	1.3e-84	294.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158351_k127_1365144_6	66875.JODY01000033_gene4354	7.562e-165	540.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
SRR25158351_k127_1365144_44	1463920.JOGB01000060_gene4803	5.219e-47	178.0	COG1545@1|root,COG1545@2|Bacteria,2IHZR@201174|Actinobacteria	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1365144_12	1246995.AFR_33700	1.035e-127	445.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DHM4@85008|Micromonosporales	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRR25158351_k127_1365144_59	1223523.H340_23253	1.413e-19	98.0	COG0789@1|root,COG0789@2|Bacteria,2I8PU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158351_k127_1365144_35	298655.KI912266_gene5423	2.008e-62	237.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU00@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1365144_14	1089544.KB912942_gene4161	6.151e-116	408.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1365144_39	1231391.AMZF01000003_gene3115	4.449e-53	196.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2W95G@28216|Betaproteobacteria,3T7RQ@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1365144_54	298654.FraEuI1c_5263	3.825e-30	130.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158351_k127_1365144_29	882083.SacmaDRAFT_2086	3.223e-79	274.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4E15A@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1365144_22	235985.BBPN01000006_gene3586	6.984e-96	321.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,2NF6J@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1365144_5	298654.FraEuI1c_5260	2.668e-173	552.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,4EUS5@85013|Frankiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158351_k127_137298_70	1229780.BN381_130018	9.717e-11	64.0	COG0496@1|root,COG0496@2|Bacteria,2IRBR@201174|Actinobacteria	201174|Actinobacteria	S	Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158351_k127_137298_39	710685.MycrhN_5758	1.311e-84	307.0	COG0510@1|root,COG0510@2|Bacteria,2I4HR@201174|Actinobacteria,23F84@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_137298_5	875328.JDM601_4208	6.863e-200	640.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,2353H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_137298_56	68199.JNZO01000024_gene4325	3.107e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,2GMXU@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158351_k127_137298_9	1123320.KB889679_gene2373	1.045e-183	585.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_137298_31	436229.JOEH01000037_gene2626	4.176e-106	357.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,2NEYF@228398|Streptacidiphilus	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_137298_7	216594.MMAR_4821	4.816e-195	616.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria,237SC@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_137298_44	656024.FsymDg_1605	1.316e-67	236.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4ESFA@85013|Frankiales	201174|Actinobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158351_k127_137298_3	479434.Sthe_2199	1.144e-210	691.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_137298_57	269800.Tfu_2132	1.961e-45	182.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4EIY6@85012|Streptosporangiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158351_k127_137298_21	1206733.BAGC01000038_gene93	1.531e-133	433.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria,4FY58@85025|Nocardiaceae	201174|Actinobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	tauD	-	1.14.11.17	ko:K03119,ko:K22303	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
SRR25158351_k127_137298_17	345341.KUTG_01457	4.461e-154	495.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,4E151@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE26	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_137298_36	710685.MycrhN_0069	6.442e-94	321.0	COG2761@1|root,COG2761@2|Bacteria,2H7YD@201174|Actinobacteria,2359N@1762|Mycobacteriaceae	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158351_k127_137298_55	1313172.YM304_39260	4.034e-48	185.0	2A84P@1|root,30X5E@2|Bacteria,2IN6P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_137298_11	222534.KB893738_gene1273	5.085e-178	566.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4ES3N@85013|Frankiales	201174|Actinobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
SRR25158351_k127_137298_6	1123320.KB889669_gene3279	1.776e-198	625.0	COG2141@1|root,COG2141@2|Bacteria,2GP93@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_137298_8	298655.KI912266_gene5004	1.388e-193	612.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_137298_62	477641.MODMU_5247	1.176e-27	125.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	GO:0005575,GO:0005576	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158351_k127_137298_18	1313172.YM304_18860	5.74e-151	490.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_137298_40	1341646.CBMO010000089_gene5601	5.122e-84	293.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,236F7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
SRR25158351_k127_137298_47	875328.JDM601_3578	9.047e-64	246.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,2387T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158351_k127_137298_65	1173020.Cha6605_2906	1.018e-18	100.0	COG1196@1|root,COG1196@2|Bacteria,1GENB@1117|Cyanobacteria	1117|Cyanobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_137298_50	479434.Sthe_0311	3.477e-55	205.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_137298_53	641491.DND132_0782	1.562e-54	202.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2X5IA@28221|Deltaproteobacteria,2MGRF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
SRR25158351_k127_137298_29	886293.Sinac_6674	2.296e-108	362.0	COG0451@1|root,COG0451@2|Bacteria,2IX9F@203682|Planctomycetes	203682|Planctomycetes	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SRR25158351_k127_137298_10	1265310.CCBD010000008_gene2784	1.879e-178	567.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_137298_2	1541065.JRFE01000014_gene1863	2.343e-222	707.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,3VMF5@52604|Pleurocapsales	1117|Cyanobacteria	Q	Copper amine oxidase, enzyme domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRR25158351_k127_137298_38	269797.Mbar_A2742	5.541e-90	318.0	COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,2NA6F@224756|Methanomicrobia	224756|Methanomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_137298_37	525368.HMPREF0591_2149	6.052e-92	313.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,233TC@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_137298_45	685727.REQ_45120	1.548e-67	242.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4FX68@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17,5.3.3.18	ko:K01692,ko:K15866	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R09837,R09839	RC00004,RC00326,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_137298_24	58344.JOEL01000012_gene2516	4.553e-126	413.0	COG2957@1|root,COG2957@2|Bacteria,2GM6J@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SRR25158351_k127_137298_48	526225.Gobs_0783	2.877e-63	231.0	COG0300@1|root,COG0300@2|Bacteria,2I2RM@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.105	ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR25158351_k127_137298_54	1429046.RR21198_4556	9.377e-50	185.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4G1CN@85025|Nocardiaceae	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158351_k127_137298_67	313589.JNB_10414	9.19e-18	92.0	COG3544@1|root,COG3544@2|Bacteria,2GMGR@201174|Actinobacteria,4FH7K@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158351_k127_137298_68	1380347.JNII01000007_gene185	5.683e-13	80.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158351_k127_137298_61	469383.Cwoe_5005	8.238e-32	128.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K03490	-	-	-	-	ko00000,ko03000	-	-	-	Cupin_2
SRR25158351_k127_137298_66	765912.Thimo_3445	1.436e-18	96.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158351_k127_137298_16	469383.Cwoe_4029	8.744e-155	492.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa1	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158351_k127_137298_41	1137269.AZWL01000005_gene2165	5.283e-84	284.0	COG0421@1|root,COG0421@2|Bacteria,2I2TN@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_137298_43	1120934.KB894415_gene3946	3.884e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4E0AR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_137298_64	929712.KI912613_gene2333	3.872e-23	105.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	COXG,Polyketide_cyc2
SRR25158351_k127_137298_51	469383.Cwoe_0206	6.075e-55	204.0	COG3527@1|root,COG3527@2|Bacteria,2IBRH@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the alpha-acetolactate decarboxylase family	budA	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
SRR25158351_k127_137298_34	436229.JOEH01000007_gene3910	2.508e-102	342.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_137298_33	1370120.AUWR01000011_gene1092	9.851e-103	350.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,235GY@1762|Mycobacteriaceae	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_137298_46	365528.KB891209_gene2154	2.63e-67	239.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4EX6V@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_137298_25	37919.EP51_12160	6.626e-123	407.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4FUH9@85025|Nocardiaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	ko:K21119	-	-	-	-	ko00000,ko00199	-	-	-	p450
SRR25158351_k127_137298_60	285535.JOEY01000127_gene5835	2.883e-41	158.0	2F2XW@1|root,33VTF@2|Bacteria,2IJD3@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_137298_12	525368.HMPREF0591_0754	2.82e-177	569.0	COG4638@1|root,COG4638@2|Bacteria,2GM3P@201174|Actinobacteria,233JP@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158351_k127_137298_1	1306990.BARG01000047_gene5804	8.177e-236	742.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	-	-	1.14.13.226	ko:K18371	ko00640,map00640	-	R10704	RC03250	ko00000,ko00001,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_3
SRR25158351_k127_137298_14	1306990.BARG01000047_gene5807	1.127e-167	533.0	COG1878@1|root,COG1878@2|Bacteria,2I8ZI@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158351_k127_137298_4	298654.FraEuI1c_5337	1.876e-204	642.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_137298_42	298655.KI912266_gene5850	8.647e-80	271.0	COG1309@1|root,COG1309@2|Bacteria,2IBE9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_137298_35	298654.FraEuI1c_5332	5.589e-100	340.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_137298_26	1172181.KB911712_gene2104	2.845e-119	390.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_137298_13	330084.JNYZ01000004_gene385	4.081e-170	557.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZX5@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_137298_30	298654.FraEuI1c_5330	1.56e-107	353.0	COG1028@1|root,COG1028@2|Bacteria,2GNIN@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_137298_27	298654.FraEuI1c_5331	2.004e-112	372.0	COG1028@1|root,COG1028@2|Bacteria	298654.FraEuI1c_5331|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_137298_0	1463861.JNXE01000003_gene3928	9.243e-277	866.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	bkdA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158351_k127_137298_19	330084.JNYZ01000004_gene396	7.147e-140	454.0	COG1960@1|root,COG1960@2|Bacteria,2IBHA@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_137298_32	298653.Franean1_3154	1.035e-103	355.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4EUM6@85013|Frankiales	201174|Actinobacteria	I	Carboxylesterase family	lipN	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158351_k127_137298_20	436229.JOEH01000008_gene4341	4.322e-137	446.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRR25158351_k127_137298_22	479432.Sros_1477	1.544e-128	428.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria,4EGS6@85012|Streptosporangiales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158351_k127_137298_28	882083.SacmaDRAFT_5546	2.5e-110	372.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4E0C4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_137298_15	525368.HMPREF0591_2686	8.438e-159	517.0	COG3804@1|root,COG3804@2|Bacteria,2I8CX@201174|Actinobacteria,2330G@1762|Mycobacteriaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	dapB_1	-	-	-	-	-	-	-	-	-	-	-	DapB_N
SRR25158351_k127_137298_71	1117319.PSPO_12367	8.721e-08	65.0	COG4976@1|root,COG4976@2|Bacteria,1QV99@1224|Proteobacteria,1T2AQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158351_k127_137298_52	1370125.AUWT01000011_gene1763	1.048e-54	196.0	COG3832@1|root,COG3832@2|Bacteria,2IFZV@201174|Actinobacteria,238M8@1762|Mycobacteriaceae	201174|Actinobacteria	S	polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_137298_63	1122939.ATUD01000003_gene3463	1.359e-25	115.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CSRN@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_137298_69	1229780.BN381_350053	5.365e-11	65.0	COG4430@1|root,COG4430@2|Bacteria,2H1K0@201174|Actinobacteria	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
SRR25158351_k127_137298_59	1117318.PRUB_10397	1.187e-41	166.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RP4C@1236|Gammaproteobacteria,2Q5CA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_137298_58	1313172.YM304_31580	4.271e-44	163.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158351_k127_137298_49	1313172.YM304_31570	4.155e-56	204.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N_3
SRR25158351_k127_137298_23	1380356.JNIK01000002_gene4894	2.875e-128	421.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU00@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_137298_72	1121933.AUHH01000010_gene2569	2.302e-05	54.0	COG1028@1|root,COG1028@2|Bacteria,2I72Q@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_137298_73	298655.KI912266_gene2745	7.549e-05	48.0	COG1545@1|root,COG1545@2|Bacteria,2IFHZ@201174|Actinobacteria	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1384681_4	362242.MUL_0819	2.007e-07	55.0	COG0300@1|root,COG1063@1|root,COG0300@2|Bacteria,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1384681_0	469383.Cwoe_2565	2.372e-300	939.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CR1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158351_k127_1384681_2	1229780.BN381_100013	6.486e-99	332.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,3UXE8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158351_k127_1384681_3	379066.GAU_3022	1.738e-10	67.0	COG1146@1|root,COG1146@2|Bacteria,1ZU19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158351_k127_1384681_1	1041522.MCOL_V224157	1.744e-102	347.0	COG2124@1|root,COG2124@2|Bacteria,2GKKN@201174|Actinobacteria,23477@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.15.13	ko:K17474	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_1428221_55	51337.XP_004668406.1	0.0003761	47.0	29KRA@1|root,2RU0E@2759|Eukaryota,39T20@33154|Opisthokonta,3BIHH@33208|Metazoa,3D2D7@33213|Bilateria,47ZQX@7711|Chordata,4942U@7742|Vertebrata,3J9Z2@40674|Mammalia,35F24@314146|Euarchontoglires,4Q0YG@9989|Rodentia	33208|Metazoa	S	FAM75 family	SPATA31E1	-	-	-	-	-	-	-	-	-	-	-	DUF4599,FAM75
SRR25158351_k127_1428221_42	2045.KR76_09710	1.108e-11	75.0	COG4968@1|root,COG4968@2|Bacteria,2GTH1@201174|Actinobacteria,4DSBA@85009|Propionibacteriales	201174|Actinobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158351_k127_1428221_47	749927.AMED_4448	1.668e-08	66.0	2CCSB@1|root,33USJ@2|Bacteria,2IPHH@201174|Actinobacteria	201174|Actinobacteria	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158351_k127_1428221_40	208444.JNYY01000001_gene5511	6.663e-15	83.0	2C1B5@1|root,3404V@2|Bacteria,2IQAF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158351_k127_1428221_9	1157638.KB892165_gene3610	3.053e-106	358.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158351_k127_1428221_4	68570.DC74_1071	3.885e-181	599.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158351_k127_1428221_43	1125863.JAFN01000001_gene1507	9.818e-11	76.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158351_k127_1428221_30	426355.Mrad2831_5139	9.813e-34	143.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2TWPJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158351_k127_1428221_51	1033734.CAET01000079_gene3557	3.558e-05	54.0	29S70@1|root,30DBH@2|Bacteria,1UB40@1239|Firmicutes,4IMGK@91061|Bacilli,1ZK45@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1428221_12	105425.BBPL01000002_gene6534	9.326e-100	340.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,2NH95@228398|Streptacidiphilus	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_1428221_36	1121877.JQKF01000030_gene2159	5.634e-21	102.0	COG1569@1|root,COG1569@2|Bacteria,2H12B@201174|Actinobacteria,4CNS9@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
SRR25158351_k127_1428221_50	670487.Ocepr_1453	1.171e-06	54.0	2EK4T@1|root,33DV8@2|Bacteria,1WKD0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1428221_14	1068980.ARVW01000001_gene5613	8.482e-90	314.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_1428221_44	1440774.Y900_007500	5.291e-10	71.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1428221_34	926550.CLDAP_28830	5.08e-23	104.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158351_k127_1428221_11	710685.MycrhN_4969	2.35e-102	372.0	COG2114@1|root,COG2909@1|root,COG3629@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3629@2|Bacteria,2GJAR@201174|Actinobacteria,2349V@1762|Mycobacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
SRR25158351_k127_1428221_15	1229780.BN381_210105	2.856e-88	300.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,3UWMW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158351_k127_1428221_48	1034347.CAHJ01000026_gene3526	1.827e-07	59.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1	ko:K00368,ko:K18683	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cupredoxin_1,SoxE
SRR25158351_k127_1428221_17	105425.BBPL01000065_gene5322	9.83e-80	275.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,2NJ35@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_1428221_49	1206741.BAFX01000102_gene1463	1.045e-06	61.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4FXXQ@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158351_k127_1428221_39	298654.FraEuI1c_2591	1.178e-17	86.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcpB	-	1.11.1.15	ko:K03386,ko:K03564	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA,HxlR,MerR_1,Redoxin
SRR25158351_k127_1428221_46	1303518.CCALI_01014	2.52e-09	61.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158351_k127_1428221_33	1229780.BN381_210073	5.645e-24	112.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1428221_52	543632.JOJL01000007_gene5396	0.000132	48.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4D8FP@85008|Micromonosporales	201174|Actinobacteria	T	Signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4
SRR25158351_k127_1428221_41	709986.Deima_0305	1.06e-14	79.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,SBP_bac_3
SRR25158351_k127_1428221_54	1269813.ATUL01000022_gene795	0.0002283	53.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1T423@1236|Gammaproteobacteria,1X2WT@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
SRR25158351_k127_1428221_22	525909.Afer_1580	4.144e-66	231.0	2CGIK@1|root,33UPP@2|Bacteria,2H4PB@201174|Actinobacteria,4CN1M@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1428221_24	1313172.YM304_27690	1.224e-57	209.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CNBV@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158351_k127_1428221_13	713586.KB900536_gene1768	2.456e-94	316.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1WW0F@135613|Chromatiales	135613|Chromatiales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158351_k127_1428221_28	1229780.BN381_80057	9.184e-47	177.0	COG1234@1|root,COG1234@2|Bacteria,2HNMK@201174|Actinobacteria,3UXIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158351_k127_1428221_20	645127.ckrop_1402	8.826e-69	247.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,22K7M@1653|Corynebacteriaceae	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158351_k127_1428221_16	591158.SSMG_03965	5.383e-88	301.0	COG0009@1|root,COG0009@2|Bacteria,2GN4J@201174|Actinobacteria	201174|Actinobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158351_k127_1428221_6	1313172.YM304_27740	3.249e-124	405.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CMZT@84992|Acidimicrobiia	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158351_k127_1428221_35	700508.D174_20020	3.986e-22	106.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,23A2G@1762|Mycobacteriaceae	201174|Actinobacteria	H	Molybdopterin converting factor, small subunit	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_1428221_32	525909.Afer_1753	4.951e-24	117.0	COG1310@1|root,COG1310@2|Bacteria,2HG96@201174|Actinobacteria,4CN7H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158351_k127_1428221_0	994479.GL877878_gene3531	2.743e-276	877.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1QR@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158351_k127_1428221_7	1313172.YM304_21870	3.147e-121	398.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
SRR25158351_k127_1428221_29	880073.Calab_1982	1.838e-44	168.0	COG0691@1|root,COG0691@2|Bacteria,2NPFK@2323|unclassified Bacteria	2|Bacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158351_k127_1428221_18	557599.MKAN_25950	1.043e-74	268.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,232QT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158351_k127_1428221_10	1157637.KB892093_gene6707	1.58e-103	345.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1428221_38	869210.Marky_1843	2.873e-20	100.0	COG0599@1|root,COG0599@2|Bacteria,1WN13@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_1428221_3	485914.Hmuk_1560	2.561e-185	609.0	COG0243@1|root,arCOG01495@2157|Archaea,2Y8AD@28890|Euryarchaeota,2417E@183963|Halobacteria	183963|Halobacteria	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SRR25158351_k127_1428221_19	485914.Hmuk_1561	2.412e-72	254.0	COG0437@1|root,arCOG01500@2157|Archaea,2XTS6@28890|Euryarchaeota,23U4H@183963|Halobacteria	183963|Halobacteria	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_10,Fer4_11,Fer4_7,Ferredoxin_N
SRR25158351_k127_1428221_27	1227500.C494_14593	6.567e-49	194.0	COG5557@1|root,arCOG02025@2157|Archaea,2XTP4@28890|Euryarchaeota,23S4Z@183963|Halobacteria	183963|Halobacteria	C	Polysulphide reductase	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SRR25158351_k127_1428221_53	1235794.C811_00982	0.0002133	52.0	COG3381@1|root,COG3381@2|Bacteria,2HUJ0@201174|Actinobacteria,4CWGN@84998|Coriobacteriia	84998|Coriobacteriia	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
SRR25158351_k127_1428221_37	1380394.JADL01000001_gene2450	1.029e-20	108.0	COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,2TS71@28211|Alphaproteobacteria,2JR2H@204441|Rhodospirillales	204441|Rhodospirillales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
SRR25158351_k127_1428221_25	378806.STAUR_0058	1.444e-55	198.0	COG0789@1|root,COG0789@2|Bacteria,1RH2U@1224|Proteobacteria,42TT2@68525|delta/epsilon subdivisions,2WR2A@28221|Deltaproteobacteria,2Z14E@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158351_k127_1428221_26	1463864.JOGO01000099_gene4248	1.723e-50	186.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158351_k127_1428221_1	298655.KI912266_gene5581	1.022e-217	679.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1428221_2	298653.Franean1_6853	1.267e-186	599.0	COG3653@1|root,COG3653@2|Bacteria,2IE6H@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_1428221_5	710686.Mycsm_00144	6.449e-127	420.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158351_k127_1428221_8	314285.KT71_11780	7.334e-111	368.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1J597@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	NADP-dependent oxidoreductases	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRR25158351_k127_1428221_21	1382306.JNIM01000001_gene661	3.35e-68	247.0	COG0842@1|root,COG0842@2|Bacteria,2G6H9@200795|Chloroflexi	2|Bacteria	V	Transport permease protein	pedC	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_1428221_31	479434.Sthe_2137	4.034e-31	126.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi,27XNW@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_143381_2	1120942.AUBM01000004_gene1763	1.458e-54	206.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4D3AW@85005|Actinomycetales	201174|Actinobacteria	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_143381_5	443255.SCLAV_p1510	3.363e-24	115.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_143381_1	1120936.KB907216_gene3796	2.743e-91	315.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4EHBR@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SRR25158351_k127_143381_0	469371.Tbis_2650	2.812e-127	440.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DZXW@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
SRR25158351_k127_143381_3	134676.ACPL_6425	8.117e-42	169.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4DB50@85008|Micromonosporales	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtC	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_6
SRR25158351_k127_143381_4	570268.ANBB01000046_gene1317	2.105e-38	149.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4EI6U@85012|Streptosporangiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158351_k127_1479440_108	1123240.ATVO01000009_gene737	6.631e-11	72.0	2C8FR@1|root,34BJJ@2|Bacteria,1P3IC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_8	298654.FraEuI1c_3065	1.91e-209	670.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158351_k127_1479440_97	66377.JOBH01000016_gene5515	4.543e-21	99.0	2DWZW@1|root,342QA@2|Bacteria,2GQ7R@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_1479440_23	366602.Caul_4261	1.546e-116	395.0	COG2130@1|root,COG2130@2|Bacteria,1MUR0@1224|Proteobacteria,2U16B@28211|Alphaproteobacteria,2KIA2@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
SRR25158351_k127_1479440_6	1229780.BN381_780004	3.632e-218	687.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158351_k127_1479440_49	1229780.BN381_310079	1.78e-66	246.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,3UXS8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158351_k127_1479440_27	656024.FsymDg_3597	1.043e-107	363.0	COG3408@1|root,COG3408@2|Bacteria,2I3UW@201174|Actinobacteria,4EXFQ@85013|Frankiales	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100,Glyco_hydro_63,Trehalase
SRR25158351_k127_1479440_67	1223523.H340_00889	1.069e-42	175.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_1479440_21	1123279.ATUS01000001_gene2396	1.171e-125	418.0	COG5361@1|root,COG5361@2|Bacteria,1NQYA@1224|Proteobacteria,1SJTP@1236|Gammaproteobacteria,1J97U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
SRR25158351_k127_1479440_51	1229780.BN381_10204	7.529e-66	235.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,3UXFS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1479440_77	1395571.TMS3_0100965	4.362e-32	141.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158351_k127_1479440_39	1463920.JOGB01000004_gene4677	4.476e-73	259.0	COG0657@1|root,COG0657@2|Bacteria,2I6Z1@201174|Actinobacteria	201174|Actinobacteria	I	Esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158351_k127_1479440_64	247156.NFA_46610	4.263e-45	179.0	COG2084@1|root,COG2084@2|Bacteria,2GNI7@201174|Actinobacteria,4FVG5@85025|Nocardiaceae	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158351_k127_1479440_99	1123321.KB905816_gene2753	8.844e-19	92.0	COG0599@1|root,COG2084@1|root,COG0599@2|Bacteria,COG2084@2|Bacteria,2GNI7@201174|Actinobacteria	201174|Actinobacteria	I	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CMD,NAD_binding_11,NAD_binding_2
SRR25158351_k127_1479440_28	1278078.G419_21389	3.959e-102	347.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4FW9P@85025|Nocardiaceae	201174|Actinobacteria	Q	Cytochrome P450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_1479440_42	1114964.L485_13840	4.348e-71	252.0	COG1028@1|root,COG1028@2|Bacteria,1QDBJ@1224|Proteobacteria,2TV7A@28211|Alphaproteobacteria,2KE8G@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1479440_75	944435.AXAJ01000001_gene196	3.216e-35	139.0	COG0346@1|root,COG0346@2|Bacteria,1RG1A@1224|Proteobacteria,2W2S8@28216|Betaproteobacteria,1K7Y9@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1479440_46	1288079.AUKN01000007_gene1946	4.572e-67	234.0	COG0500@1|root,COG2226@2|Bacteria,2I3AK@201174|Actinobacteria	201174|Actinobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_1479440_13	1219035.NT2_11_00210	2.488e-175	562.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria,2JZUE@204457|Sphingomonadales	204457|Sphingomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
SRR25158351_k127_1479440_69	1448389.BAVQ01000005_gene3137	3.511e-40	154.0	COG0748@1|root,COG0748@2|Bacteria,2IP0W@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_1479440_54	1206101.AZXC01000032_gene3378	3.084e-54	202.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_112	1172185.KB911509_gene295	2.484e-09	59.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4G39Q@85025|Nocardiaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158351_k127_1479440_53	1463856.JOHY01000006_gene116	7.078e-56	217.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_91	1160718.SU9_08000	3.927e-24	116.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158351_k127_1479440_98	1283283.ATXA01000001_gene311	4.122e-19	101.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4ETSH@85013|Frankiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158351_k127_1479440_106	2045.KR76_09765	6.066e-12	76.0	COG1714@1|root,COG1714@2|Bacteria,2I05B@201174|Actinobacteria,4DVUI@85009|Propionibacteriales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_92	1229780.BN381_10081	6.11e-23	108.0	COG1714@1|root,COG1714@2|Bacteria,2GZKA@201174|Actinobacteria	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158351_k127_1479440_22	1229780.BN381_40040	2.96e-124	428.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria	201174|Actinobacteria	T	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158351_k127_1479440_37	1033730.CAHG01000008_gene3077	1.543e-76	282.0	COG3325@1|root,COG3325@2|Bacteria,2IGIW@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_88	216594.MMAR_4436	1.083e-24	110.0	2B2M4@1|root,31V6I@2|Bacteria,2GV2T@201174|Actinobacteria,23DZT@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_72	1095767.CAHD01000194_gene205	3.1e-37	143.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158351_k127_1479440_104	1089545.KB913037_gene8466	7.247e-13	80.0	2DFS9@1|root,2ZSWU@2|Bacteria,2I7G3@201174|Actinobacteria	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR25158351_k127_1479440_87	390989.JOEG01000012_gene3310	3.782e-25	116.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria,4DKUX@85008|Micromonosporales	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158351_k127_1479440_96	1298863.AUEP01000012_gene3663	2.439e-21	101.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4DSDH@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_11	1123023.JIAI01000004_gene7847	6.132e-187	601.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158351_k127_1479440_102	1283287.KB822584_gene1326	2.792e-17	87.0	2DY9S@1|root,348TG@2|Bacteria,2H8I0@201174|Actinobacteria	201174|Actinobacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
SRR25158351_k127_1479440_15	1121946.AUAX01000025_gene6397	1.493e-163	523.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4D8VN@85008|Micromonosporales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158351_k127_1479440_2	1121946.AUAX01000025_gene6398	5.274e-293	916.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4DHU6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
SRR25158351_k127_1479440_29	1283287.KB822579_gene2178	3.615e-100	337.0	COG0560@1|root,COG0560@2|Bacteria,2GKRQ@201174|Actinobacteria,4DRDM@85009|Propionibacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_1479440_33	67373.JOBF01000016_gene4817	2.08e-83	297.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158351_k127_1479440_100	1229780.BN381_80172	5.822e-18	93.0	2DXTJ@1|root,346GW@2|Bacteria,2H9GA@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_110	1279017.AQYJ01000026_gene73	1.218e-10	66.0	2DXTJ@1|root,346GW@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_19	1123257.AUFV01000007_gene317	4.173e-134	438.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1X74H@135614|Xanthomonadales	135614|Xanthomonadales	F	Adenosine/AMP deaminase	-	-	-	-	-	-	-	-	-	-	-	-	A_deaminase
SRR25158351_k127_1479440_9	228410.NE0091	1.199e-208	676.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria,3722H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,Usp
SRR25158351_k127_1479440_43	639283.Snov_0827	7.949e-71	263.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TUNG@28211|Alphaproteobacteria,3F1TP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein transmembrane region	MA20_22750	-	-	-	-	-	-	-	-	-	-	-	DsbD
SRR25158351_k127_1479440_66	1197906.CAJQ02000043_gene1970	3.066e-44	169.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,3JVFP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Cytochrome c biogenesis protein	soxV	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158351_k127_1479440_56	1168059.KB899087_gene1905	2.502e-51	200.0	COG1073@1|root,COG1073@2|Bacteria,1MVAA@1224|Proteobacteria,2U0SU@28211|Alphaproteobacteria,3EZZA@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRR25158351_k127_1479440_74	351607.Acel_2096	2.701e-35	149.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	GO:0005575,GO:0005576	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158351_k127_1479440_109	1120960.ATXG01000005_gene2425	9.476e-11	74.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4FKU4@85023|Microbacteriaceae	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
SRR25158351_k127_1479440_71	926550.CLDAP_27190	2.58e-37	158.0	COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	vpr	GO:0005575,GO:0005576	3.4.21.4	ko:K01312,ko:K14647	ko02024,ko04080,ko04972,ko04974,ko05164,map02024,map04080,map04972,map04974,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110,ko04147	-	-	-	FlgD_ig,Inhibitor_I9,PA,Peptidase_S8,SLH,Trypsin,VCBS
SRR25158351_k127_1479440_90	1142394.PSMK_17330	1.87e-24	108.0	COG4828@1|root,COG4828@2|Bacteria,2J4U0@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR25158351_k127_1479440_3	1380356.JNIK01000013_gene4027	6.481e-285	897.0	COG1804@1|root,COG1804@2|Bacteria,2GMGE@201174|Actinobacteria,4EX6M@85013|Frankiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1479440_116	1121004.ATVC01000010_gene1053	0.000402	50.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KSHZ@206351|Neisseriales	206351|Neisseriales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
SRR25158351_k127_1479440_20	1306174.JODP01000016_gene7073	1.039e-131	451.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
SRR25158351_k127_1479440_115	1173264.KI913949_gene4183	3.763e-05	52.0	COG0739@1|root,COG0739@2|Bacteria,1G1GS@1117|Cyanobacteria,1H8FP@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158351_k127_1479440_79	1211815.CBYP010000034_gene2147	1.299e-30	137.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4EX87@85013|Frankiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
SRR25158351_k127_1479440_12	710111.FraQA3DRAFT_1294	1.221e-179	576.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1479440_18	67373.JOBF01000019_gene5773	4.165e-138	446.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1479440_101	1068978.AMETH_5097	1.515e-17	94.0	COG2197@1|root,COG2197@2|Bacteria,2IFSK@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	uvrY	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_1479440_114	1068980.ARVW01000001_gene5552	1.544e-07	53.0	COG2197@1|root,COG2197@2|Bacteria,2IFSK@201174|Actinobacteria,4E84J@85010|Pseudonocardiales	201174|Actinobacteria	K	Homeodomain-like domain	uvrY	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_1479440_41	1229780.BN381_70073	9.41e-72	259.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,3UWFU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158351_k127_1479440_103	1313172.YM304_37380	4.313e-15	78.0	COG1722@1|root,COG1722@2|Bacteria,2HD2Z@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158351_k127_1479440_113	693661.Arcve_2110	1.96e-08	65.0	arCOG06689@1|root,arCOG06689@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,SpoIIM
SRR25158351_k127_1479440_38	285535.JOEY01000061_gene8701	2.535e-75	274.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria	201174|Actinobacteria	G	xylulose kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158351_k127_1479440_73	1122247.C731_0984	3.036e-36	154.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_1479440_80	105425.BBPL01000072_gene3633	1.601e-29	123.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria,2NJSD@228398|Streptacidiphilus	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_14	103733.JNYO01000012_gene2803	1.078e-168	542.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2GIXE@201174|Actinobacteria,4E0ZQ@85010|Pseudonocardiales	201174|Actinobacteria	EK	Cystathionine beta-synthase	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158351_k127_1479440_16	1123024.AUII01000003_gene3287	7.762e-150	493.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158351_k127_1479440_86	405948.SACE_0308	1.976e-25	109.0	2E3SC@1|root,32YPX@2|Bacteria,2HPCF@201174|Actinobacteria,4E4BJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158351_k127_1479440_25	1313172.YM304_07490	4.951e-111	368.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CNED@84992|Acidimicrobiia	84992|Acidimicrobiia	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3
SRR25158351_k127_1479440_0	324602.Caur_1881	4.32e-312	975.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158351_k127_1479440_40	1313172.YM304_07470	9.103e-73	263.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158351_k127_1479440_10	1313172.YM304_07520	4.789e-201	640.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4CMSG@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mg-chelatase subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRR25158351_k127_1479440_84	33876.JNXY01000030_gene2834	7.414e-26	119.0	COG2852@1|root,COG2852@2|Bacteria,2GSDS@201174|Actinobacteria,4DMGJ@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158351_k127_1479440_4	1313172.YM304_07620	2.216e-245	775.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_63	1054213.HMPREF9946_02362	6.538e-46	172.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2U70V@28211|Alphaproteobacteria,2JT1J@204441|Rhodospirillales	204441|Rhodospirillales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158351_k127_1479440_76	1313172.YM304_07630	1.082e-32	136.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4CP4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158351_k127_1479440_57	525904.Tter_0694	1.047e-50	192.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcd	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
SRR25158351_k127_1479440_65	653045.Strvi_4574	2.478e-44	179.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1479440_111	504728.K649_12960	3.495e-10	62.0	COG1826@1|root,COG1826@2|Bacteria,1WKJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158351_k127_1479440_61	1150599.MPHLEI_15046	1.042e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,2343I@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1479440_107	58123.JOFJ01000015_gene4529	3.928e-11	76.0	COG3026@1|root,COG3026@2|Bacteria,2IRR9@201174|Actinobacteria,4EP65@85012|Streptosporangiales	201174|Actinobacteria	T	antisigma factor binding	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB
SRR25158351_k127_1479440_81	1313172.YM304_07660	4.453e-29	119.0	2CC1Y@1|root,32TCV@2|Bacteria,2HGD4@201174|Actinobacteria,4CNAQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158351_k127_1479440_50	309801.trd_A0320	2.421e-66	241.0	COG0265@1|root,COG0265@2|Bacteria,2G8RK@200795|Chloroflexi,27Y6G@189775|Thermomicrobia	189775|Thermomicrobia	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_1479440_89	1313172.YM304_07670	1.148e-24	108.0	2FBA6@1|root,343GA@2|Bacteria,2H78Y@201174|Actinobacteria,4CN8Z@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1479440_44	1313172.YM304_07710	5.18e-70	251.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria	201174|Actinobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158351_k127_1479440_31	1313172.YM304_07700	3.736e-84	289.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158351_k127_1479440_52	1313172.YM304_07690	1.075e-61	229.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158351_k127_1479440_59	1229780.BN381_30044	1.585e-48	183.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,3UWW3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158351_k127_1479440_26	1137268.AZXF01000038_gene4052	6.998e-110	368.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EM3I@85012|Streptosporangiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158351_k127_1479440_47	525909.Afer_0201	6.459e-67	243.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CMZJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158351_k127_1479440_32	1313172.YM304_07750	1.024e-83	284.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1479440_58	1220583.GOACH_15_00020	7.298e-50	186.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4GCW6@85026|Gordoniaceae	201174|Actinobacteria	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158351_k127_1479440_95	247156.NFA_42090	9.048e-22	111.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4FVR6@85025|Nocardiaceae	201174|Actinobacteria	GL	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158351_k127_1479440_83	585531.HMPREF0063_11482	1.133e-26	120.0	COG0494@1|root,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4DQI9@85009|Propionibacteriales	201174|Actinobacteria	L	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158351_k127_1479440_30	345341.KUTG_00490	3.699e-90	319.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158351_k127_1479440_5	1206720.BAFQ01000139_gene3478	5.412e-243	773.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4FUE4@85025|Nocardiaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158351_k127_1479440_48	1313172.YM304_07790	1.59e-66	246.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1479440_82	269800.Tfu_2201	1.078e-28	123.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4EFKW@85012|Streptosporangiales	201174|Actinobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158351_k127_1479440_36	710111.FraQA3DRAFT_1003	4.594e-80	276.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4ERI1@85013|Frankiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158351_k127_1479440_55	1313172.YM304_07800	6.681e-53	203.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158351_k127_1479440_60	452652.KSE_49050	1.168e-47	186.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,2M21V@2063|Kitasatospora	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158351_k127_1479440_24	562970.Btus_0655	3.184e-114	380.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,4HAAQ@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator (AsnC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
SRR25158351_k127_1479440_78	1120950.KB892768_gene5344	4.439e-32	139.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DNEM@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_1479440_70	1313172.YM304_09020	6.34e-39	156.0	COG0314@1|root,COG0314@2|Bacteria,2HG21@201174|Actinobacteria,4CN80@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158351_k127_1479440_17	1313172.YM304_09040	3.102e-141	457.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158351_k127_1479440_85	1313172.YM304_05060	9.999e-26	125.0	COG1413@1|root,COG1413@2|Bacteria,2HA0J@201174|Actinobacteria,4CNCY@84992|Acidimicrobiia	84992|Acidimicrobiia	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158351_k127_1479440_62	1463864.JOGO01000006_gene4991	1.325e-46	183.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158351_k127_1479440_94	1313172.YM304_05090	3.175e-22	111.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158351_k127_1479440_7	525909.Afer_1871	5.901e-214	702.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CMW1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158351_k127_1479440_1	47839.CCAU010000009_gene1461	1.742e-300	944.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,23407@1762|Mycobacteriaceae	201174|Actinobacteria	O	assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158351_k127_1479440_35	42256.RradSPS_2724	5.852e-81	287.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158351_k127_1479440_93	1463921.JODF01000020_gene1413	1.04e-22	112.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158351_k127_1479440_45	1370120.AUWR01000060_gene4085	2.315e-68	242.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,233X3@1762|Mycobacteriaceae	201174|Actinobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158351_k127_1479440_34	1280950.HJO_00285	7.316e-82	280.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,2U82N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158351_k127_1479440_68	2002.JOEQ01000006_gene1382	1.147e-41	161.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4EGC3@85012|Streptosporangiales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158351_k127_1481530_56	222534.KB893778_gene5095	6.821e-28	124.0	COG1672@1|root,COG1672@2|Bacteria,2IGAA@201174|Actinobacteria,4ET1R@85013|Frankiales	201174|Actinobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158351_k127_1481530_53	298654.FraEuI1c_3299	6.546e-31	131.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	ydgC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1481530_17	298655.KI912266_gene5041	1.966e-131	445.0	COG0318@1|root,COG0318@2|Bacteria,2I91U@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1481530_36	479434.Sthe_0531	1.413e-69	250.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	2|Bacteria	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1481530_46	243233.MCA2966	9.157e-43	167.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales	135618|Methylococcales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158351_k127_1481530_55	1120936.KB907218_gene3470	2.302e-29	127.0	COG2050@1|root,COG2050@2|Bacteria,2H09W@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1481530_48	1333998.M2A_1085	1.659e-40	166.0	COG0406@1|root,COG0406@2|Bacteria,1MYD7@1224|Proteobacteria,2TVST@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158351_k127_1481530_68	591157.SSLG_06263	0.0004005	51.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158351_k127_1481530_1	1123320.KB889689_gene527	3.22e-229	730.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1481530_14	487521.OCU_43040	1.126e-151	499.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158351_k127_1481530_32	469371.Tbis_2929	2.704e-85	291.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DY3G@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_1481530_10	298655.KI912266_gene5992	1.791e-158	509.0	COG0183@1|root,COG0183@2|Bacteria,2GKWR@201174|Actinobacteria,4ES3R@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1481530_30	1121422.AUMW01000009_gene3324	1.55e-86	306.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,262AS@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1481530_58	931627.MycrhDRAFT_1216	2.839e-21	103.0	COG2030@1|root,COG2030@2|Bacteria,2IKE4@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158351_k127_1481530_52	298654.FraEuI1c_3297	3.196e-31	133.0	COG0346@1|root,COG0346@2|Bacteria,2IFSX@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158351_k127_1481530_7	1343740.M271_44305	1.371e-169	554.0	COG0318@1|root,COG0318@2|Bacteria,2GMYS@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1481530_50	883126.HMPREF9710_02534	7.045e-38	156.0	29SRR@1|root,30DXN@2|Bacteria,1RD8Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
SRR25158351_k127_1481530_25	931627.MycrhDRAFT_2394	2.092e-99	333.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,23ABY@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1481530_33	1123320.KB889685_gene2187	1.177e-84	289.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1481530_35	1394178.AWOO02000024_gene5605	9.047e-78	274.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1481530_59	33876.JNXY01000021_gene4774	3.844e-21	105.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4DDX1@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158351_k127_1481530_19	99598.Cal7507_4485	1.356e-118	386.0	COG0235@1|root,COG0235@2|Bacteria,1G10W@1117|Cyanobacteria,1HMDU@1161|Nostocales	1117|Cyanobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158351_k127_1481530_64	1201293.AKXQ01000008_gene714	8.963e-12	75.0	2DDZV@1|root,32U2A@2|Bacteria,1MZU0@1224|Proteobacteria,1SQ2I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1481530_2	1283283.ATXA01000001_gene1168	4.678e-194	619.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1481530_24	1519464.HY22_08585	1.25e-103	355.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158351_k127_1481530_49	467200.ACFA01000519_gene2178	6.041e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1481530_51	1122611.KB903966_gene5067	7.484e-34	144.0	2EWES@1|root,33PT7@2|Bacteria,2IF44@201174|Actinobacteria,4EN2H@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1481530_47	298655.KI912266_gene6119	1.059e-42	169.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
SRR25158351_k127_1481530_38	1298863.AUEP01000006_gene3336	5.419e-60	224.0	COG4221@1|root,COG4221@2|Bacteria,2I8VU@201174|Actinobacteria,4DPNG@85009|Propionibacteriales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1481530_65	1380390.JIAT01000010_gene4657	1.637e-10	68.0	COG4454@1|root,COG4454@2|Bacteria,2I7WC@201174|Actinobacteria,4CTCK@84995|Rubrobacteria	84995|Rubrobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158351_k127_1481530_39	56110.Oscil6304_5208	4.559e-58	217.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1481530_21	557599.MKAN_03230	8.842e-112	383.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,23CXI@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
SRR25158351_k127_1481530_9	298655.KI912266_gene4642	2.937e-161	523.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1481530_42	211114.JOEF01000019_gene491	1.178e-50	196.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4DXF7@85010|Pseudonocardiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158351_k127_1481530_34	1380386.JIAW01000007_gene3788	2.989e-79	278.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,23B1Y@1762|Mycobacteriaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_1481530_4	298654.FraEuI1c_5256	6.634e-181	580.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1481530_43	469383.Cwoe_1969	1.219e-49	186.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria,4CT3G@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158351_k127_1481530_3	1219035.NT2_01_05360	1.311e-182	587.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2K212@204457|Sphingomonadales	204457|Sphingomonadales	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158351_k127_1481530_31	1123320.KB889585_gene1873	4.007e-86	296.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158351_k127_1481530_12	1123320.KB889585_gene1872	1.491e-155	508.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1481530_22	1192034.CAP_1145	1.431e-108	369.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,438C4@68525|delta/epsilon subdivisions,2WYM4@28221|Deltaproteobacteria,2YWIJ@29|Myxococcales	28221|Deltaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_1481530_6	1229780.BN381_50055	9.04e-171	564.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,3UWBH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	feaB	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1481530_27	309801.trd_A0429	1.701e-98	340.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi,27Y50@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1481530_11	1229780.BN381_50037	2.548e-156	505.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,3UX69@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnA4	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158351_k127_1481530_44	644966.Tmar_1828	1.565e-48	187.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,3WCKK@538999|Clostridiales incertae sedis	186801|Clostridia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158351_k127_1481530_8	1123320.KB889687_gene937	2.175e-169	547.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1481530_37	1278073.MYSTI_04826	9.482e-64	228.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1481530_18	710111.FraQA3DRAFT_1346	7.189e-126	426.0	COG0318@1|root,COG0318@2|Bacteria,2I91U@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1481530_29	1219035.NT2_06_02560	7.595e-89	318.0	28K5H@1|root,2Z9U4@2|Bacteria,1NXCU@1224|Proteobacteria,2USX2@28211|Alphaproteobacteria,2K6H8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1481530_28	207954.MED92_14528	7.269e-92	309.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1XHXA@135619|Oceanospirillales	135619|Oceanospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158351_k127_1481530_57	298655.KI912267_gene7582	5.106e-25	111.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,4EWT6@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158351_k127_1481530_67	749414.SBI_08387	5.114e-05	50.0	2ATH5@1|root,31J0W@2|Bacteria,2IQ8W@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF202
SRR25158351_k127_1481530_23	1206735.BAGG01000028_gene1235	6.692e-105	350.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,4FVS0@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1481530_62	298653.Franean1_6856	4.533e-15	79.0	2DS7S@1|root,33EWX@2|Bacteria,2GWXQ@201174|Actinobacteria,4EWUK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1481530_26	1463820.JOGW01000004_gene4552	2.745e-99	359.0	COG2141@1|root,COG2141@2|Bacteria,2IB78@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1481530_15	561175.KB894095_gene2603	1.129e-138	460.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4EHNH@85012|Streptosporangiales	201174|Actinobacteria	EGKP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1481530_45	247634.GPB2148_339	5.91e-47	174.0	2F5RB@1|root,330DX@2|Bacteria,1Q5TY@1224|Proteobacteria,1STT1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1481530_5	298654.FraEuI1c_1928	2.613e-174	555.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1481530_40	247633.GP2143_07434	4.091e-57	207.0	COG1051@1|root,COG1051@2|Bacteria,1QUPQ@1224|Proteobacteria	1224|Proteobacteria	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158351_k127_1481530_13	1120949.KB903295_gene2218	5.462e-152	499.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158351_k127_1481530_60	266117.Rxyl_2440	1.347e-18	91.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,4CPZF@84995|Rubrobacteria	84995|Rubrobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1
SRR25158351_k127_1481530_66	264951.V5G686	2.478e-06	61.0	COG1073@1|root,2RYKB@2759|Eukaryota,39ZW1@33154|Opisthokonta,3P26T@4751|Fungi,3QVGI@4890|Ascomycota,20GDQ@147545|Eurotiomycetes	4751|Fungi	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
SRR25158351_k127_1481530_20	287986.DV20_01500	1.516e-115	381.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4E07A@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158351_k127_1481530_0	298654.FraEuI1c_2472	4.417e-239	766.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1481530_16	1088721.NSU_1480	1.076e-131	432.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1481530_54	1088721.NSU_1479	1.418e-30	125.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1481530_41	1123320.KB889664_gene1119	2.428e-54	203.0	COG3618@1|root,COG3618@2|Bacteria,2IB8W@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1481530_61	1123020.AUIE01000001_gene2002	2.22e-15	77.0	COG1028@1|root,COG1028@2|Bacteria,1PHKF@1224|Proteobacteria,1RX6C@1236|Gammaproteobacteria,1YHY0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1510757_16	68219.JNXI01000010_gene5728	3.739e-12	66.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158351_k127_1510757_20	381666.H16_A3198	1.207e-05	49.0	2BH9F@1|root,32BAX@2|Bacteria,1NC2G@1224|Proteobacteria,2VSK4@28216|Betaproteobacteria,1KHIV@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1510757_12	1217656.F964_03571	6.63e-21	98.0	COG3311@1|root,COG3311@2|Bacteria,1RFU1@1224|Proteobacteria,1RYMB@1236|Gammaproteobacteria,3NNCN@468|Moraxellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1510757_22	479431.Namu_0788	0.000267	45.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4EV02@85013|Frankiales	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
SRR25158351_k127_1510757_21	1463934.JOCF01000009_gene4679	4.57e-05	55.0	COG0455@1|root,COG0455@2|Bacteria,2HT5K@201174|Actinobacteria	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1510757_18	1122222.AXWR01000017_gene2863	5.978e-10	71.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_1510757_9	1356852.N008_21575	1.218e-55	211.0	COG2723@1|root,COG2723@2|Bacteria,4NI2I@976|Bacteroidetes,47KM2@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
SRR25158351_k127_1510757_19	1158292.JPOE01000002_gene3478	1.166e-09	68.0	COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,2VQPY@28216|Betaproteobacteria,1KMSE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,DLH,Hydrolase_4,Peptidase_S15
SRR25158351_k127_1510757_7	410359.Pcal_1311	9.332e-78	277.0	COG1064@1|root,arCOG01455@2157|Archaea,2XQ4K@28889|Crenarchaeota	28889|Crenarchaeota	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1510757_11	189753.AXAS01000113_gene28	2.869e-38	156.0	COG3239@1|root,COG3239@2|Bacteria,1NQ1W@1224|Proteobacteria,2UHA6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158351_k127_1510757_0	1313172.YM304_31110	1.018e-241	758.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158351_k127_1510757_13	1123320.KB889664_gene1114	5.147e-15	77.0	2BZD4@1|root,33Y08@2|Bacteria,2GY7R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1510757_17	1123320.KB889664_gene1114	8.126e-12	69.0	2BZD4@1|root,33Y08@2|Bacteria,2GY7R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1510757_3	1123320.KB889664_gene1113	9.476e-116	385.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1510757_24	111781.Lepto7376_1451	0.0008911	52.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G33B@1117|Cyanobacteria,1HA93@1150|Oscillatoriales	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158351_k127_1510757_23	1206743.BAGM01000035_gene79	0.0008399	49.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4FWKX@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_1510757_14	1172186.KB911464_gene4735	2.598e-14	78.0	COG4319@1|root,COG4319@2|Bacteria,2IJ30@201174|Actinobacteria,238V3@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_1510757_4	1229780.BN381_400010	1.474e-114	377.0	COG2141@1|root,COG2141@2|Bacteria,2I9FZ@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1510757_5	1282876.BAOK01000001_gene2836	9.789e-82	283.0	COG4943@1|root,COG4943@2|Bacteria,1QZSA@1224|Proteobacteria,2TYDN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158351_k127_1510757_2	710111.FraQA3DRAFT_1401	6.811e-119	388.0	COG3173@1|root,COG3173@2|Bacteria,2IEPN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_1510757_6	1220534.B655_1263	2.989e-79	278.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,23PE0@183925|Methanobacteria	183925|Methanobacteria	P	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1510757_8	634498.mru_1438	2.065e-66	235.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,23PH8@183925|Methanobacteria	183925|Methanobacteria	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1510757_1	1449049.JONW01000012_gene6	1.948e-123	403.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2U14P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1510757_10	1116232.AHBF01000080_gene8453	1.007e-41	159.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_54	1229780.BN381_80413	5.278e-77	272.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158351_k127_1527617_69	1041522.MCOL_V204900	4.276e-57	209.0	COG1028@1|root,COG1028@2|Bacteria	1041522.MCOL_V204900|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1527617_109	985762.SAGN_09392	3.174e-05	55.0	COG1388@1|root,COG1388@2|Bacteria,1V7FX@1239|Firmicutes,4HJS7@91061|Bacilli,4GXPS@90964|Staphylococcaceae	91061|Bacilli	M	Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells	sceD	-	-	-	-	-	-	-	-	-	-	-	Transglycosylas
SRR25158351_k127_1527617_57	1120950.KB892743_gene3110	8.415e-72	261.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4DQD7@85009|Propionibacteriales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158351_k127_1527617_19	1229780.BN381_100028	5.987e-128	419.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158351_k127_1527617_87	1279019.ARQK01000054_gene187	7.881e-27	117.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1X13D@135613|Chromatiales	135613|Chromatiales	P	Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRR25158351_k127_1527617_14	1229780.BN381_10292	1.341e-133	444.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1527617_50	1229780.BN381_130053	3.365e-86	305.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria	201174|Actinobacteria	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR25158351_k127_1527617_5	1229780.BN381_430003	2.316e-182	593.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1527617_82	525909.Afer_0797	5.055e-33	150.0	COG3884@1|root,COG3884@2|Bacteria,2H0CD@201174|Actinobacteria,4CNBC@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
SRR25158351_k127_1527617_56	1242864.D187_006746	8.597e-75	259.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,42S6B@68525|delta/epsilon subdivisions,2WNKV@28221|Deltaproteobacteria,2YXNN@29|Myxococcales	28221|Deltaproteobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_29	1333998.M2A_2518	6.098e-106	351.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2VGEQ@28211|Alphaproteobacteria,4BS1Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158351_k127_1527617_58	479433.Caci_1632	5.434e-71	245.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	gca	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
SRR25158351_k127_1527617_30	468556.AQYG01000051_gene2649	2.838e-104	347.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4GBEY@85026|Gordoniaceae	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158351_k127_1527617_45	1283283.ATXA01000001_gene378	1.678e-90	308.0	COG0300@1|root,COG0300@2|Bacteria,2I5VJ@201174|Actinobacteria,4EXE8@85013|Frankiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1527617_46	290397.Adeh_0962	1.021e-89	304.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158351_k127_1527617_53	469383.Cwoe_1814	6.595e-78	271.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158351_k127_1527617_106	1380386.JIAW01000002_gene5621	1.005e-06	59.0	2C8CM@1|root,32RKV@2|Bacteria,2GPP7@201174|Actinobacteria,23A53@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4262)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4262
SRR25158351_k127_1527617_98	1265313.HRUBRA_01348	2.357e-15	89.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1527617_55	298655.KI912266_gene6060	2.725e-76	271.0	COG0683@1|root,COG0683@2|Bacteria,2IBGV@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1527617_104	1280949.HAD_17376	1.134e-07	61.0	COG2010@1|root,COG2010@2|Bacteria,1N8E1@1224|Proteobacteria,2UG6N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158351_k127_1527617_72	710111.FraQA3DRAFT_3383	1.443e-54	203.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria,4ETB0@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1527617_8	1380356.JNIK01000011_gene1978	8.938e-151	503.0	COG1226@1|root,COG1226@2|Bacteria,2GKPB@201174|Actinobacteria	201174|Actinobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid,TrkA_N
SRR25158351_k127_1527617_59	1313172.YM304_24600	3.141e-70	244.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (isoleucine patch	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
SRR25158351_k127_1527617_9	350058.Mvan_2384	5.796e-145	486.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23F6M@1762|Mycobacteriaceae	201174|Actinobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158351_k127_1527617_41	1229780.BN381_360040	2.719e-92	329.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipL	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_1527617_83	83332.Rv1532c	2.544e-32	147.0	COG2050@1|root,COG2050@2|Bacteria,2GV7U@201174|Actinobacteria,23BQU@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1527617_84	1123320.KB889689_gene500	1.516e-30	126.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ywlE	-	2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6	ko:K01104,ko:K01808,ko:K07566,ko:K20201	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030,R10463	RC00376,RC00434,RC00745	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016	-	-	-	LMWPc
SRR25158351_k127_1527617_39	298655.KI912266_gene5746	4.219e-94	317.0	COG0411@1|root,COG0411@2|Bacteria,2H5WA@201174|Actinobacteria	201174|Actinobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1527617_67	1463885.KL578414_gene8897	9.116e-63	232.0	COG0683@1|root,COG0683@2|Bacteria,2GMDG@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1527617_0	1123320.KB889566_gene5769	1.06e-294	932.0	COG0410@1|root,COG0559@1|root,COG4177@1|root,COG0410@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158351_k127_1527617_99	1463853.JOHW01000003_gene2049	3.58e-13	81.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1527617_62	1144275.COCOR_06641	4.075e-66	237.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,42ZK4@68525|delta/epsilon subdivisions,2WUTV@28221|Deltaproteobacteria,2YVBM@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158351_k127_1527617_33	2074.JNYD01000027_gene7368	1.941e-101	341.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4E39N@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1527617_49	1123320.KB889722_gene7571	2.434e-86	308.0	COG5285@1|root,COG5285@2|Bacteria,2IC8K@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158351_k127_1527617_48	337191.KTR9_2848	1.275e-87	303.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4GC2U@85026|Gordoniaceae	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158351_k127_1527617_66	1123320.KB889562_gene6675	8.102e-63	231.0	COG4221@1|root,COG4221@2|Bacteria,2IGP3@201174|Actinobacteria	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1527617_36	67373.JOBF01000003_gene166	1.269e-97	327.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_1527617_23	29540.C481_01280	1.043e-123	419.0	COG0596@1|root,arCOG01648@2157|Archaea,2XWCD@28890|Euryarchaeota,23V50@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158351_k127_1527617_71	767817.Desgi_3217	4.942e-55	207.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,25EG6@186801|Clostridia,265GT@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1527617_10	710111.FraQA3DRAFT_3330	2.343e-144	466.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4ETYJ@85013|Frankiales	201174|Actinobacteria	S	epoxide hydrolase	-	-	3.3.2.9	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
SRR25158351_k127_1527617_2	106370.Francci3_2165	5.816e-241	754.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ERZH@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1527617_20	1120948.KB903219_gene651	1.023e-126	419.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DYUI@85010|Pseudonocardiales	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158351_k127_1527617_79	512565.AMIS_70200	1.021e-36	153.0	COG1051@1|root,COG1051@2|Bacteria,2INBQ@201174|Actinobacteria,4DM6X@85008|Micromonosporales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158351_k127_1527617_65	1207055.C100_18185	7.096e-63	233.0	COG1028@1|root,COG1028@2|Bacteria,1R6NY@1224|Proteobacteria,2TVUT@28211|Alphaproteobacteria,2K2I8@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_52	1229780.BN381_10252	9.149e-81	288.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,3UX9P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_1527617_15	101510.RHA1_ro02355	6.527e-132	436.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4FYCE@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_1527617_1	1206741.BAFX01000197_gene3573	3.554e-245	772.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FUZR@85025|Nocardiaceae	201174|Actinobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_1527617_103	1280949.HAD_11365	3.749e-08	63.0	COG1359@1|root,COG1359@2|Bacteria,1N6JS@1224|Proteobacteria,2UEN1@28211|Alphaproteobacteria,43YMX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158351_k127_1527617_11	1229780.BN381_80187	2.586e-143	464.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,3UX44@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158351_k127_1527617_21	1229780.BN381_80188	2.263e-124	417.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,3UX11@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_1527617_24	525904.Tter_2416	3.764e-122	399.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158351_k127_1527617_105	1123392.AQWL01000004_gene2812	4.014e-07	63.0	COG0589@1|root,COG0589@2|Bacteria,1PE08@1224|Proteobacteria,2VNHV@28216|Betaproteobacteria,1KSNV@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_1527617_77	13689.BV96_00229	9.981e-41	157.0	COG5517@1|root,COG5517@2|Bacteria,1RKHJ@1224|Proteobacteria,2UJ37@28211|Alphaproteobacteria,2K5MJ@204457|Sphingomonadales	204457|Sphingomonadales	Q	Ring hydroxylating beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_1527617_64	1342299.Z947_87	2.594e-65	237.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2U2T5@28211|Alphaproteobacteria,3ZWM3@60136|Sulfitobacter	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1527617_92	675635.Psed_0560	1.924e-21	108.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SRR25158351_k127_1527617_86	1292020.H483_0100125	1.768e-27	124.0	COG2050@1|root,COG2050@2|Bacteria,2GK27@201174|Actinobacteria	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1527617_80	1449353.JQMQ01000004_gene6121	1.115e-36	151.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,2NFB0@228398|Streptacidiphilus	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Y_phosphatase3
SRR25158351_k127_1527617_26	1120950.KB892771_gene1287	3.075e-111	379.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4DPZ7@85009|Propionibacteriales	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRR25158351_k127_1527617_63	67352.JODS01000010_gene4891	1.727e-65	228.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158351_k127_1527617_102	298654.FraEuI1c_7201	1.095e-09	71.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1527617_75	263358.VAB18032_16525	1.822e-47	175.0	COG3339@1|root,COG3339@2|Bacteria,2IMCR@201174|Actinobacteria,4DGJP@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158351_k127_1527617_91	1463903.JOIZ01000007_gene4075	8.906e-22	100.0	2A1S7@1|root,30Q0V@2|Bacteria,2GTY5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
SRR25158351_k127_1527617_3	58344.JOEL01000002_gene2028	2.141e-213	699.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1527617_70	1206735.BAGG01000058_gene2365	3.681e-56	205.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria,4FU2T@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_60	1123279.ATUS01000003_gene454	7.644e-70	247.0	COG1028@1|root,COG1028@2|Bacteria,1R3VH@1224|Proteobacteria,1RRZ0@1236|Gammaproteobacteria,1J9UB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_101	1408452.JAGZ01000006_gene793	1.227e-10	65.0	COG2128@1|root,COG2128@2|Bacteria,2I9B5@201174|Actinobacteria,2384H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_1527617_89	557599.MKAN_00910	1.528e-22	99.0	COG2128@1|root,COG2128@2|Bacteria,2I9B5@201174|Actinobacteria,2384H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_1527617_25	1254432.SCE1572_45270	2.373e-119	398.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_1527617_96	487521.OCU_19360	4.728e-17	93.0	COG1028@1|root,COG1028@2|Bacteria,2IJC8@201174|Actinobacteria,23D4M@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1527617_68	487521.OCU_19360	4.013e-62	228.0	COG1028@1|root,COG1028@2|Bacteria,2IJC8@201174|Actinobacteria,23D4M@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1527617_43	1348338.ADILRU_2126	1.121e-91	324.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4FN0I@85023|Microbacteriaceae	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_1527617_73	1380356.JNIK01000021_gene4666	5.255e-53	201.0	COG1024@1|root,COG1024@2|Bacteria,2HSJH@201174|Actinobacteria,4EV1S@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1527617_40	1323361.JPOC01000033_gene1596	6.022e-94	317.0	COG1024@1|root,COG1024@2|Bacteria,2HEIS@201174|Actinobacteria,4FWC0@85025|Nocardiaceae	201174|Actinobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1527617_37	1440774.Y900_012760	9.745e-97	331.0	COG2159@1|root,COG2159@2|Bacteria,2HSH2@201174|Actinobacteria,236WQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_1527617_34	298654.FraEuI1c_3723	1.042e-99	349.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_1527617_18	1123320.KB889719_gene7199	7.702e-130	436.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158351_k127_1527617_95	1229780.BN381_10319	1.341e-18	94.0	COG2050@1|root,COG2050@2|Bacteria,2I11Y@201174|Actinobacteria,3UXR4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1527617_7	1150599.MPHLEI_12921	6.915e-164	524.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,233JC@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA5	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1527617_74	443255.SCLAV_p1227	2.357e-51	203.0	COG0596@1|root,COG0596@2|Bacteria,2GY3A@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_1527617_4	1123320.KB889747_gene7192	1.581e-196	631.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD19	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1527617_17	1121937.AUHJ01000001_gene365	2.011e-130	426.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria	1224|Proteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1527617_27	710111.FraQA3DRAFT_1345	3.454e-110	369.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158351_k127_1527617_88	1121033.AUCF01000014_gene1318	5.633e-26	124.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,2U5BV@28211|Alphaproteobacteria,2JU23@204441|Rhodospirillales	204441|Rhodospirillales	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1527617_78	1123320.KB889689_gene537	7.303e-40	157.0	COG2050@1|root,COG2050@2|Bacteria,2GK27@201174|Actinobacteria	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1527617_61	2074.JNYD01000009_gene5282	2.043e-68	243.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria,4DZ02@85010|Pseudonocardiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	htdY	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158351_k127_1527617_76	58344.JOEL01000002_gene1727	3.931e-42	171.0	COG4221@1|root,COG4221@2|Bacteria,2GQNJ@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1527617_81	1380386.JIAW01000003_gene826	4.175e-34	143.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,234NC@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_51	1343740.M271_40325	7.378e-81	286.0	COG1063@1|root,COG1063@2|Bacteria,2IDE4@201174|Actinobacteria	201174|Actinobacteria	E	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,Glu_dehyd_C
SRR25158351_k127_1527617_85	1161401.ASJA01000004_gene2169	2.375e-28	125.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2TWPJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158351_k127_1527617_47	436229.JOEH01000018_gene1178	1.745e-88	308.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria,2NMUF@228398|Streptacidiphilus	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1527617_16	487521.OCU_51110	3.933e-131	433.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,2361S@1762|Mycobacteriaceae	201174|Actinobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158351_k127_1527617_35	1449069.JMLO01000027_gene3181	3.524e-99	333.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FXBH@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1527617_13	1205680.CAKO01000030_gene4841	6.187e-139	459.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2U1CT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1527617_107	1160137.KB907307_gene3922	1.901e-06	61.0	COG0683@1|root,COG0683@2|Bacteria,2IE69@201174|Actinobacteria,4G8YH@85025|Nocardiaceae	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1527617_90	1122609.AUGT01000009_gene3245	6.382e-22	111.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1527617_22	1121272.KB903292_gene3947	7.294e-124	423.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4DJIF@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158351_k127_1527617_28	419610.Mext_4851	4.673e-108	369.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,1JSC2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158351_k127_1527617_42	1123320.KB889685_gene2187	4.83e-92	314.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1527617_38	1123320.KB889585_gene1939	3.122e-94	315.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1527617_31	644283.Micau_3956	1.268e-103	350.0	COG2132@1|root,COG2132@2|Bacteria,2HU57@201174|Actinobacteria,4DBEA@85008|Micromonosporales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
SRR25158351_k127_1527617_93	469371.Tbis_2520	2.863e-21	96.0	2DDBJ@1|root,2ZHEX@2|Bacteria,2GXRW@201174|Actinobacteria,4E7RA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1527617_12	298655.KI912266_gene5429	3.27e-142	479.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1527617_32	1343740.M271_20800	1.884e-101	353.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1527617_44	66373.JOFQ01000003_gene6058	1.846e-91	310.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158351_k127_1527617_6	1476876.JOJO01000015_gene6088	3.475e-179	594.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD16	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1568731_3	298655.KI912266_gene4967	1.132e-102	362.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU9G@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1568731_9	1229780.BN381_130242	4.682e-26	117.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,3UWY5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRR25158351_k127_1568731_1	478741.JAFS01000002_gene50	8.84e-143	462.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
SRR25158351_k127_1568731_5	518766.Rmar_2587	2.103e-50	188.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
SRR25158351_k127_1568731_4	518766.Rmar_2588	3.474e-94	321.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	asrB	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158351_k127_1568731_2	743836.AYNA01000054_gene83	1.835e-117	392.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,2TVJC@28211|Alphaproteobacteria,36ZAX@31993|Methylocystaceae	28211|Alphaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
SRR25158351_k127_1568731_0	543632.JOJL01000027_gene2900	8.983e-189	599.0	COG3259@1|root,COG3259@2|Bacteria,2GQ33@201174|Actinobacteria,4DABR@85008|Micromonosporales	201174|Actinobacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SRR25158351_k127_1568731_8	1223523.H340_28280	1.494e-27	124.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158351_k127_1568731_10	426716.JOAJ01000001_gene1139	2.55e-09	61.0	COG0298@1|root,COG0298@2|Bacteria,2IREM@201174|Actinobacteria,4G3I0@85025|Nocardiaceae	201174|Actinobacteria	O	HupF/HypC family	hypC1	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158351_k127_1568731_7	58123.JOFJ01000014_gene5035	4.334e-31	130.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1679396_30	1075090.GOAMR_21_00350	1.062e-49	191.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4GABT@85026|Gordoniaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1679396_4	298655.KI912266_gene5986	3.624e-143	472.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_1679396_21	298654.FraEuI1c_3295	1.196e-74	264.0	COG0146@1|root,COG0146@2|Bacteria,2IA3H@201174|Actinobacteria	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158351_k127_1679396_0	298654.FraEuI1c_3295	2.428e-207	666.0	COG0146@1|root,COG0146@2|Bacteria,2IA3H@201174|Actinobacteria	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158351_k127_1679396_17	298654.FraEuI1c_3296	7.549e-80	292.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158351_k127_1679396_29	298654.FraEuI1c_3296	1.008e-50	185.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158351_k127_1679396_19	1229780.BN381_310099	6.055e-79	286.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
SRR25158351_k127_1679396_44	101510.RHA1_ro11025	1.139e-26	118.0	2F0H0@1|root,33TJV@2|Bacteria,2HZJZ@201174|Actinobacteria,4G4N2@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_7	487521.OCU_07630	1.303e-121	404.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,233DU@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1679396_20	298654.FraEuI1c_3303	8.94e-78	273.0	COG1960@1|root,COG1960@2|Bacteria,2HXD5@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158351_k127_1679396_13	1229780.BN381_150001	9.604e-93	325.0	COG1807@1|root,COG1807@2|Bacteria,2IITJ@201174|Actinobacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158351_k127_1679396_2	710421.Mycch_2953	1.596e-159	513.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2341M@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_37	317655.Sala_0905	2.755e-40	155.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,2U5BU@28211|Alphaproteobacteria,2KDFN@204457|Sphingomonadales	204457|Sphingomonadales	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1679396_50	1220534.B655_2051	2.574e-07	57.0	COG0599@1|root,arCOG02151@2157|Archaea	2157|Archaea	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_1679396_28	235985.BBPN01000029_gene2421	3.061e-52	191.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria,2NJ10@228398|Streptacidiphilus	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1679396_41	298655.KI912266_gene5748	8.326e-37	153.0	COG2030@1|root,COG2030@2|Bacteria,2IGBP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158351_k127_1679396_27	547163.BN979_00160	1.993e-53	195.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria,2355H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158351_k127_1679396_26	266117.Rxyl_0346	3.667e-56	214.0	COG1028@1|root,COG1028@2|Bacteria,2GNIN@201174|Actinobacteria,4CT0P@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1679396_33	1120950.KB892753_gene6079	2.261e-44	181.0	COG1028@1|root,COG1028@2|Bacteria,2GP7P@201174|Actinobacteria,4DR0M@85009|Propionibacteriales	201174|Actinobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1679396_22	56110.Oscil6304_5208	1.14e-67	244.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1679396_15	369723.Strop_4194	1.43e-90	316.0	COG1162@1|root,COG1162@2|Bacteria,2GMDX@201174|Actinobacteria,4DBP0@85008|Micromonosporales	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158351_k127_1679396_24	1206101.AZXC01000032_gene3378	3.864e-59	213.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_38	1463854.JOHT01000007_gene3374	3.602e-39	156.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_1679396_16	1380347.JNII01000005_gene3884	2.787e-81	277.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria,4EV3E@85013|Frankiales	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
SRR25158351_k127_1679396_46	1120949.KB903326_gene3159	2.687e-23	104.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_52	106370.Francci3_2829	1.026e-05	57.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4EV73@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1679396_40	146922.JOFU01000073_gene7911	7.85e-37	162.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
SRR25158351_k127_1679396_48	468556.AQYG01000043_gene136	3.892e-18	98.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1679396_9	767817.Desgi_0469	9.66e-108	363.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24AD9@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	DUF35_N,Thiolase_C,Thiolase_N,ketoacyl-synt
SRR25158351_k127_1679396_23	146922.JOFU01000057_gene806	6.656e-62	228.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158351_k127_1679396_14	350058.Mvan_2341	1.819e-91	312.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,2351C@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1679396_12	1056816.JAFQ01000004_gene6347	4.199e-94	321.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,4FX60@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1679396_32	1206731.BAGB01000047_gene5213	9.879e-48	186.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4G052@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1679396_11	709797.CSIRO_2216	5.089e-102	364.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria,3JTP6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_16340	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1679396_51	234267.Acid_5751	2.951e-07	60.0	2DB8V@1|root,2Z7SX@2|Bacteria	2|Bacteria	S	Gluconate 2-dehydrogenase	-	-	1.1.99.3	ko:K06152	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	Gluconate_2-dh3
SRR25158351_k127_1679396_6	1463858.JOHR01000001_gene6186	6.754e-122	417.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	2|Bacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
SRR25158351_k127_1679396_25	760568.Desku_2792	8.406e-58	224.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,24AKI@186801|Clostridia,263E3@186807|Peptococcaceae	186801|Clostridia	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158351_k127_1679396_35	1160718.SU9_33418	1.087e-43	187.0	COG3391@1|root,COG3391@2|Bacteria,2H4SV@201174|Actinobacteria	201174|Actinobacteria	MU	Bacterial Ig-like domain (group 3)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,TIG
SRR25158351_k127_1679396_31	105420.BBPO01000067_gene3919	2.248e-48	184.0	2CEQM@1|root,33UYD@2|Bacteria,2IDST@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_42	67275.JOAP01000049_gene831	2.1e-35	149.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158351_k127_1679396_1	66875.JODY01000009_gene2061	2.44e-166	535.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	calB	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1679396_34	405948.SACE_2942	8.275e-44	173.0	COG0454@1|root,COG0456@2|Bacteria,2IPMN@201174|Actinobacteria,4E7UE@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1679396_36	1160718.SU9_03231	2.156e-40	155.0	COG0346@1|root,COG0346@2|Bacteria,2II0X@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1679396_10	469383.Cwoe_0960	6.412e-105	356.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1679396_3	1123320.KB889689_gene530	1.865e-146	486.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD17	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1679396_43	1464048.JNZS01000014_gene3014	3.31e-30	125.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria,4DEAN@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_1679396_39	487521.OCU_14880	7.332e-37	160.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,23EWU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_1679396_5	1144307.PMI04_01150	6.992e-133	433.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2TR13@28211|Alphaproteobacteria,2KCUT@204457|Sphingomonadales	204457|Sphingomonadales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158351_k127_1679396_18	1121937.AUHJ01000005_gene2239	2.979e-79	276.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RNYC@1236|Gammaproteobacteria,4685I@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_1679396_8	710111.FraQA3DRAFT_4470	2.255e-110	370.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_47	46429.BV95_01229	3.958e-19	89.0	2DW8W@1|root,33Z3K@2|Bacteria,1NRVZ@1224|Proteobacteria,2UP67@28211|Alphaproteobacteria,2K9GN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_45	1144307.PMI04_03352	2.057e-24	106.0	2DW8W@1|root,33Z3K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1679396_49	1440774.Y900_024645	4.44e-17	88.0	2B0NY@1|root,31T0Q@2|Bacteria,2ICKX@201174|Actinobacteria,237U9@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1680982_17	1306990.BARG01000053_gene6388	1.049e-18	98.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1680982_16	1172186.KB911472_gene5369	5.504e-40	160.0	COG3751@1|root,COG3751@2|Bacteria,2HN62@201174|Actinobacteria	201174|Actinobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
SRR25158351_k127_1680982_15	927658.AJUM01000042_gene1473	1.948e-40	165.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,2FVE1@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1680982_19	649831.L083_4705	2.11e-13	76.0	COG0346@1|root,COG0346@2|Bacteria,2IN2S@201174|Actinobacteria,4DJH8@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1680982_0	1229780.BN381_10229	2.011e-147	507.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria,3UXIZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRR25158351_k127_1680982_3	67373.JOBF01000003_gene295	2.69e-106	359.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1680982_14	1121468.AUBR01000025_gene2973	5.532e-50	191.0	COG1215@1|root,COG1215@2|Bacteria,1UK60@1239|Firmicutes,24IGY@186801|Clostridia,42J7I@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_1680982_5	3218.PP1S13_396V6.1	5.733e-100	341.0	COG0673@1|root,KOG2741@2759|Eukaryota,37JGU@33090|Viridiplantae,3G8AH@35493|Streptophyta	35493|Streptophyta	GQ	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158351_k127_1680982_2	1123320.KB889690_gene282	3.138e-114	404.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria	201174|Actinobacteria	KL	helicase	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158351_k127_1680982_9	329726.AM1_0723	1.358e-85	291.0	COG3555@1|root,COG3555@2|Bacteria,1G0W9@1117|Cyanobacteria	1117|Cyanobacteria	O	Aspartyl asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
SRR25158351_k127_1680982_7	1144275.COCOR_06824	4.656e-98	340.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YX7Y@29|Myxococcales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1680982_13	1121920.AUAU01000018_gene1786	4.735e-50	193.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR25158351_k127_1680982_11	1449048.JQKU01000024_gene4030	1.725e-55	216.0	COG0741@1|root,COG0741@2|Bacteria,2IBCH@201174|Actinobacteria,2359I@1762|Mycobacteriaceae	201174|Actinobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460,NLPC_P60,SLT,SLT_2
SRR25158351_k127_1680982_8	1048339.KB913029_gene2164	1.817e-93	327.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4EVCM@85013|Frankiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158351_k127_1680982_12	502025.Hoch_1760	1.702e-50	207.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria	1224|Proteobacteria	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158351_k127_1680982_20	1385515.N791_03000	0.0001606	53.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1X4SV@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158351_k127_1680982_1	1121106.JQKB01000054_gene4466	4.946e-147	493.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2JPKU@204441|Rhodospirillales	204441|Rhodospirillales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158351_k127_1680982_4	1160137.KB907308_gene6796	2.275e-105	363.0	COG0596@1|root,COG0596@2|Bacteria,2HHT8@201174|Actinobacteria,4G09S@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_1680982_6	28444.JODQ01000014_gene6748	9.939e-100	340.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4EGWW@85012|Streptosporangiales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158351_k127_1680982_10	222534.KB893783_gene5258	9.389e-68	246.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4ESN0@85013|Frankiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158351_k127_1682886_13	1229780.BN381_20106	6.64e-23	102.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,3UW8A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158351_k127_1682886_0	196162.Noca_3921	6.463e-189	605.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4DU4P@85009|Propionibacteriales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_1682886_7	1313172.YM304_33110	1.15e-62	221.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CN75@84992|Acidimicrobiia	84992|Acidimicrobiia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158351_k127_1682886_11	264732.Moth_0078	2.002e-30	136.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,42G72@68295|Thermoanaerobacterales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158351_k127_1682886_3	525909.Afer_1597	4.895e-117	387.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CMVQ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158351_k127_1682886_2	106370.Francci3_3961	2.527e-132	439.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4ERCR@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158351_k127_1682886_10	1121422.AUMW01000011_gene150	3.515e-32	143.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,261HE@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158351_k127_1682886_6	1313172.YM304_33050	1.409e-67	241.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CN5A@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158351_k127_1682886_9	1077144.AGFF01000026_gene689	1.14e-39	170.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria	201174|Actinobacteria	K	domain protein	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158351_k127_1682886_8	1229780.BN381_20095	1.731e-60	227.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,3UWGN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158351_k127_1682886_1	469371.Tbis_3171	1.906e-169	548.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4E07J@85010|Pseudonocardiales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158351_k127_1682886_5	290399.Arth_1206	1.49e-71	255.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,1W7DZ@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158351_k127_1682886_14	285514.JNWO01000031_gene1322	2.456e-12	72.0	COG1430@1|root,COG1430@2|Bacteria,2IKSE@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158351_k127_1682886_4	1121877.JQKF01000013_gene255	7.89e-89	309.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CMT9@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein of unknown function (DUF933)	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158351_k127_1682886_12	164757.Mjls_1943	2.159e-29	120.0	COG5517@1|root,COG5517@2|Bacteria,2IFNT@201174|Actinobacteria,238N6@1762|Mycobacteriaceae	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_1683508_33	281090.Lxx22677	3.166e-20	92.0	COG2026@1|root,COG2026@2|Bacteria,2GRQR@201174|Actinobacteria,4FSY9@85023|Microbacteriaceae	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158351_k127_1683508_34	469383.Cwoe_0848	4.951e-20	91.0	COG2161@1|root,COG2161@2|Bacteria,2HRW6@201174|Actinobacteria,4CTZM@84995|Rubrobacteria	84995|Rubrobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158351_k127_1683508_31	1134912.AJTV01000019_gene3217	3.132e-22	103.0	COG0454@1|root,COG0456@2|Bacteria,1N009@1224|Proteobacteria,2U6PP@28211|Alphaproteobacteria,370FU@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158351_k127_1683508_35	82654.Pse7367_1152	1.584e-08	60.0	COG4453@1|root,COG4453@2|Bacteria,1GJ1S@1117|Cyanobacteria,1HGR6@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
SRR25158351_k127_1683508_32	1382304.JNIL01000001_gene1710	1.828e-21	100.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli,279EA@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158351_k127_1683508_22	1449069.JMLO01000005_gene1529	2.537e-57	216.0	COG0121@1|root,COG0121@2|Bacteria,2HJG9@201174|Actinobacteria,4G6QI@85025|Nocardiaceae	201174|Actinobacteria	S	Phosphoinositide phospholipase C, Ca2+-dependent	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1
SRR25158351_k127_1683508_24	391616.OA238_c05330	1.504e-50	193.0	COG0596@1|root,COG0596@2|Bacteria,1P092@1224|Proteobacteria,2UV5T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_1683508_29	1030157.AFMP01000010_gene533	7.028e-29	133.0	28MAM@1|root,33QJ2@2|Bacteria,1R3EQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1683508_17	1313172.YM304_38280	1.322e-90	321.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CNT1@84992|Acidimicrobiia	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1683508_13	1313172.YM304_38290	2.305e-119	406.0	COG0577@1|root,COG0577@2|Bacteria,2GMC4@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	hrtB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1683508_15	1313172.YM304_38300	1.785e-113	383.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158351_k127_1683508_16	263358.VAB18032_09840	4.644e-101	344.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4DHAF@85008|Micromonosporales	201174|Actinobacteria	C	Aldo/keto reductase family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_1683508_1	471852.Tcur_2562	7.779e-219	687.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4EGGS@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158351_k127_1683508_12	342113.DM82_6345	6.931e-124	416.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VPTU@28216|Betaproteobacteria,1KDJU@119060|Burkholderiaceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinase, N-terminal domain protein	xylB2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158351_k127_1683508_37	1121090.KB894691_gene2634	2.634e-07	63.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,1ZBEY@1386|Bacillus	91061|Bacilli	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_1683508_27	1504822.CCNO01000015_gene689	1.286e-40	162.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158351_k127_1683508_38	28444.JODQ01000010_gene3249	1.583e-05	58.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4EHT1@85012|Streptosporangiales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158351_k127_1683508_8	1206744.BAGL01000042_gene1182	2.783e-131	461.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GKSQ@201174|Actinobacteria,4FW36@85025|Nocardiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1683508_20	457570.Nther_1748	4.012e-73	259.0	COG0388@1|root,COG0388@2|Bacteria,1V357@1239|Firmicutes,24GBQ@186801|Clostridia	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_1683508_0	446471.Xcel_2128	5.304e-243	756.0	COG1249@1|root,COG1249@2|Bacteria,2I6E8@201174|Actinobacteria	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1683508_19	105422.BBPM01000026_gene4151	2.465e-85	295.0	COG5031@1|root,COG5031@2|Bacteria,2IF2J@201174|Actinobacteria,2NHXK@228398|Streptacidiphilus	201174|Actinobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1683508_25	443218.AS9A_2840	1.767e-50	193.0	COG1309@1|root,COG1309@2|Bacteria,2IMHK@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1683508_21	1123024.AUII01000009_gene1954	1.781e-60	227.0	2A651@1|root,30UXH@2|Bacteria,2IERM@201174|Actinobacteria,4EBDG@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_1683508_18	1048339.KB913029_gene4056	1.782e-85	296.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria,4EWE7@85013|Frankiales	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
SRR25158351_k127_1683508_14	1045009.AFXQ01000017_gene264	4.065e-116	385.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,1W8QY@1268|Micrococcaceae	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1683508_5	1137271.AZUM01000004_gene4234	1.845e-146	470.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4DZDQ@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM luciferase family oxidoreductase, group 1	yvbT	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1683508_30	443218.AS9A_2001	4.86e-28	126.0	2DP3D@1|root,330CN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1683508_2	1229780.BN381_210099	2.072e-178	575.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,3UX6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158351_k127_1683508_3	1229780.BN381_210099	4.38e-171	557.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,3UX6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158351_k127_1683508_40	557599.MKAN_06480	6.046e-05	46.0	COG3832@1|root,COG3832@2|Bacteria,2GPQ7@201174|Actinobacteria,23EV7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_1683508_10	1313172.YM304_03940	3.666e-126	428.0	COG0168@1|root,COG0168@2|Bacteria	2|Bacteria	P	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158351_k127_1683508_9	1313172.YM304_03930	1.059e-127	422.0	COG0569@1|root,COG0569@2|Bacteria,2HH1S@201174|Actinobacteria,4CP21@84992|Acidimicrobiia	84992|Acidimicrobiia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158351_k127_1683508_6	247634.GPB2148_3615	2.693e-144	476.0	COG5285@1|root,COG5285@2|Bacteria,1NXM8@1224|Proteobacteria	1224|Proteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158351_k127_1683508_36	68170.KL590511_gene2984	1.998e-07	56.0	COG3576@1|root,COG3576@2|Bacteria,2I46F@201174|Actinobacteria,4EDRQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_1683508_7	1279017.AQYJ01000029_gene3571	1.13e-136	452.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,1RPIM@1236|Gammaproteobacteria,46DF1@72275|Alteromonadaceae	1236|Gammaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1683508_28	83332.Rv3032A	8.756e-35	144.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,2396T@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1683508_4	1206735.BAGG01000066_gene2890	2.242e-160	516.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,4FWN7@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158351_k127_1683508_26	1123024.AUII01000001_gene2958	1.393e-45	168.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria,4E5UH@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158351_k127_1683508_39	1229172.JQFA01000004_gene897	1.999e-05	53.0	COG1235@1|root,COG1235@2|Bacteria,1G1UR@1117|Cyanobacteria,1H6XF@1150|Oscillatoriales	1117|Cyanobacteria	S	beta-lactamase superfamily i	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158351_k127_1683508_23	215803.DB30_2102	1.987e-55	208.0	COG2905@1|root,COG3176@1|root,COG2905@2|Bacteria,COG3176@2|Bacteria,1PRVG@1224|Proteobacteria,439UA@68525|delta/epsilon subdivisions,2X57U@28221|Deltaproteobacteria,2Z08J@29|Myxococcales	28221|Deltaproteobacteria	T	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,cNMP_binding
SRR25158351_k127_1683508_11	1229780.BN381_100019	4.646e-125	413.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1694974_5	1313172.YM304_35300	6.707e-89	306.0	COG0463@1|root,COG0463@2|Bacteria,2HGY7@201174|Actinobacteria,4CNYB@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_1694974_11	298655.KI912266_gene3037	4.651e-10	63.0	COG0463@1|root,COG0463@2|Bacteria,2IG3X@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PqqD
SRR25158351_k127_1694974_9	1382356.JQMP01000004_gene574	3.886e-33	143.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi,27XSJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158351_k127_1694974_8	643473.KB235930_gene1524	3.237e-39	161.0	COG2227@1|root,COG2227@2|Bacteria,1GCG8@1117|Cyanobacteria,1HQ16@1161|Nostocales	1117|Cyanobacteria	H	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_21
SRR25158351_k127_1694974_7	1168059.KB899087_gene44	5.261e-53	214.0	COG0438@1|root,COG0438@2|Bacteria,1RF3D@1224|Proteobacteria,2UGI9@28211|Alphaproteobacteria,3F07D@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158351_k127_1694974_6	713586.KB900536_gene871	5.837e-67	258.0	COG3774@1|root,COG3774@2|Bacteria,1QZYU@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase sugar-binding region containing DXD motif	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug
SRR25158351_k127_1694974_10	1038858.AXBA01000023_gene485	2.405e-16	91.0	2CGDF@1|root,34388@2|Bacteria,1NBRV@1224|Proteobacteria,2UJWH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1694974_3	330084.JNYZ01000010_gene6836	1.667e-115	388.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EARD@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,Sulfatase
SRR25158351_k127_1694974_1	1894.JOER01000003_gene2827	1.378e-130	429.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158351_k127_1694974_0	321332.CYB_1464	2.651e-173	556.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria	1117|Cyanobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_8
SRR25158351_k127_1694974_2	717785.HYPMC_3795	1.039e-120	395.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,3N6HU@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	putrescine	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158351_k127_1694974_4	1156935.QWE_15102	3.162e-100	338.0	COG1177@1|root,COG1177@2|Bacteria,1N3TB@1224|Proteobacteria,2U23R@28211|Alphaproteobacteria,4B8ND@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter permease	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158351_k127_1712983_14	1121272.KB903290_gene4828	8.735e-47	182.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DA36@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1712983_2	1121946.AUAX01000001_gene2165	2.393e-119	415.0	COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria,4DMCS@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158351_k127_1712983_1	1449976.KALB_3115	2.385e-130	447.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_1712983_7	298655.KI912266_gene605	3.282e-90	321.0	COG2141@1|root,COG2141@2|Bacteria,2INA6@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1712983_8	1123320.KB889686_gene723	4.036e-82	299.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_1712983_9	1123261.AXDW01000006_gene2482	1.284e-80	278.0	COG2267@1|root,COG2267@2|Bacteria,1MUFB@1224|Proteobacteria,1RYM9@1236|Gammaproteobacteria,1X49N@135614|Xanthomonadales	135614|Xanthomonadales	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158351_k127_1712983_18	1463887.KL589992_gene378	2.518e-14	83.0	2F3YA@1|root,33WQA@2|Bacteria,2IG3Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_15	479431.Namu_4826	2.694e-31	139.0	COG0515@1|root,COG0515@2|Bacteria,2I34D@201174|Actinobacteria,4EXFC@85013|Frankiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_19	1894.JOER01000017_gene4871	8.702e-13	80.0	2F3YA@1|root,33WQA@2|Bacteria,2IG3Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_3	134676.ACPL_436	1.705e-107	357.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4D9RZ@85008|Micromonosporales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_1712983_0	63737.Npun_R0280	2.968e-150	491.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria,1HKPP@1161|Nostocales	1117|Cyanobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
SRR25158351_k127_1712983_6	208444.JNYY01000024_gene435	1.648e-90	312.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4DZ5Z@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158351_k127_1712983_10	243164.DET0762	3.831e-62	224.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi,34CXZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_22	479432.Sros_5861	2.231e-08	66.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4EG4Y@85012|Streptosporangiales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158351_k127_1712983_21	1121926.AXWO01000027_gene332	8.143e-10	70.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4EYJJ@85014|Glycomycetales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158351_k127_1712983_5	105422.BBPM01000026_gene4151	8.343e-92	314.0	COG5031@1|root,COG5031@2|Bacteria,2IF2J@201174|Actinobacteria,2NHXK@228398|Streptacidiphilus	201174|Actinobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_16	1229780.BN381_330005	3.24e-22	103.0	2B3ZZ@1|root,31WQ4@2|Bacteria,2GXQG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_4	298655.KI912267_gene7294	4.499e-92	319.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1712983_13	1247963.JPHU01000014_gene979	3.79e-50	188.0	COG1216@1|root,COG1216@2|Bacteria,1QY6A@1224|Proteobacteria,2TXHY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1712983_11	391625.PPSIR1_24779	1.403e-59	215.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_1712983_17	502025.Hoch_0529	3.007e-17	83.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158351_k127_1712983_12	1150626.PHAMO_40104	7.204e-52	199.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TVPU@28211|Alphaproteobacteria,2JR6Q@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the LDH MDH superfamily	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158351_k127_1737013_7	247633.GP2143_06664	3.934e-118	391.0	COG0318@1|root,COG0318@2|Bacteria,1MVJ1@1224|Proteobacteria,1RS4E@1236|Gammaproteobacteria,1J5NR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1737013_33	525909.Afer_0443	5.611e-42	158.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CN66@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158351_k127_1737013_5	1313172.YM304_08960	4.771e-121	406.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CMUH@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158351_k127_1737013_34	1229780.BN381_130035	8.33e-42	170.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,3UWXZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	FR47-like protein	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158351_k127_1737013_25	1229780.BN381_130031	6.713e-55	203.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,3UWTU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158351_k127_1737013_42	1120949.KB903309_gene1106	2.314e-27	123.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4DDER@85008|Micromonosporales	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158351_k127_1737013_32	671143.DAMO_2419	2.618e-42	178.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158351_k127_1737013_18	512565.AMIS_37890	4.156e-66	249.0	COG3191@1|root,COG3191@2|Bacteria,2GJKQ@201174|Actinobacteria,4DCUG@85008|Micromonosporales	201174|Actinobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
SRR25158351_k127_1737013_38	1265310.CCBD010000023_gene4272	6.033e-32	138.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria,235RZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_1737013_9	1313172.YM304_08920	9.664e-94	338.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CN11@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158351_k127_1737013_45	443143.GM18_1120	6.002e-25	109.0	COG3448@1|root,COG3448@2|Bacteria,1QXNX@1224|Proteobacteria,43C4S@68525|delta/epsilon subdivisions,2X7F6@28221|Deltaproteobacteria,43UX4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_1737013_10	429009.Adeg_1759	2.781e-90	319.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158351_k127_1737013_39	1313172.YM304_08850	1.301e-31	127.0	COG0736@1|root,COG0736@2|Bacteria,2HGFC@201174|Actinobacteria,4CND0@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158351_k127_1737013_0	1229780.BN381_130026	0.0	1161.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,3UWEV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158351_k127_1737013_4	696369.KI912183_gene2524	1.673e-121	406.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,260XD@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_1737013_35	1229780.BN381_130024	1.261e-40	156.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,3UWN9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158351_k127_1737013_26	1463900.JOIX01000020_gene402	2.08e-54	197.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158351_k127_1737013_8	710111.FraQA3DRAFT_5586	2.296e-115	390.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
SRR25158351_k127_1737013_51	4792.ETI47983	4.971e-06	55.0	COG2272@1|root,KOG1516@2759|Eukaryota,3Q7WX@4776|Peronosporales	4776|Peronosporales	I	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158351_k127_1737013_22	1313172.YM304_08770	2.326e-63	226.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CNBD@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158351_k127_1737013_31	1380393.JHVP01000002_gene1841	3.373e-43	164.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4ESN1@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158351_k127_1737013_2	1313172.YM304_08750	1.814e-139	449.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CMSV@84992|Acidimicrobiia	84992|Acidimicrobiia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158351_k127_1737013_14	351607.Acel_0333	2.991e-73	254.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4EREE@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158351_k127_1737013_21	1229780.BN381_450073	5.354e-64	221.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,3UWJ3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158351_k127_1737013_27	1121877.JQKF01000009_gene526	2.459e-53	191.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4CN1Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158351_k127_1737013_49	866774.HMPREF9248_0553	3.336e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4CWQV@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158351_k127_1737013_36	525909.Afer_0421	4.182e-37	140.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CNX6@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158351_k127_1737013_11	1121877.JQKF01000009_gene527	6.982e-88	307.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CN1I@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158351_k127_1737013_20	525909.Afer_0419	4.313e-64	227.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CMZ1@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158351_k127_1737013_1	1229780.BN381_450077	6.959e-158	509.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,3UWEW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158351_k127_1737013_29	525909.Afer_0417	2.368e-44	173.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CN1G@84992|Acidimicrobiia	84992|Acidimicrobiia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158351_k127_1737013_47	526225.Gobs_4489	6.85e-17	86.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4ETGZ@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158351_k127_1737013_17	1229780.BN381_450080	1.632e-66	233.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,3UWH1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158351_k127_1737013_41	411467.BACCAP_02892	4.773e-30	129.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,269CK@186813|unclassified Clostridiales	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158351_k127_1737013_15	1171373.PACID_25540	9.397e-71	244.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DNFZ@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158351_k127_1737013_24	1229780.BN381_450083	2.344e-55	199.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,3UWN2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158351_k127_1737013_46	1313172.YM304_08380	1.245e-21	107.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CNZU@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158351_k127_1737013_12	525909.Afer_0410	1.741e-83	286.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CMX7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158351_k127_1737013_40	484019.THA_1226	3.811e-31	129.0	COG0198@1|root,COG0198@2|Bacteria,2GD31@200918|Thermotogae	200918|Thermotogae	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158351_k127_1737013_23	525909.Afer_0408	9.425e-63	226.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CMZN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158351_k127_1737013_44	525909.Afer_0407	5.575e-26	117.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CN9S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158351_k127_1737013_50	685727.REQ_35780	6.199e-13	79.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4G2ZP@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158351_k127_1737013_16	635013.TherJR_0303	1.589e-68	240.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,261KH@186807|Peptococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158351_k127_1737013_6	1229780.BN381_450091	2.016e-118	400.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,3UW7M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158351_k127_1737013_43	1229780.BN381_450092	2.988e-27	121.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,3UWV3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158351_k127_1737013_30	1313172.YM304_08290	2.467e-44	162.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CN5R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158351_k127_1737013_3	1229780.BN381_450094	5.139e-139	447.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,3UWDY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158351_k127_1737013_37	68194.JNXR01000013_gene5815	3.457e-34	133.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158351_k127_1737013_19	1313172.YM304_08260	1.388e-65	231.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CN29@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158351_k127_1737013_13	1123322.KB904651_gene466	1.979e-81	281.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158351_k127_1737013_28	543632.JOJL01000008_gene5717	6.033e-46	168.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4DDDS@85008|Micromonosporales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158351_k127_1737013_48	656024.FsymDg_3963	1.704e-15	76.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158351_k127_1781014_0	1394178.AWOO02000034_gene8341	6.87e-138	450.0	COG2141@1|root,COG3255@1|root,COG2141@2|Bacteria,COG3255@2|Bacteria,2GKP1@201174|Actinobacteria,4EHH5@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase,SCP2
SRR25158351_k127_1781014_2	749927.AMED_3584	1.079e-54	208.0	COG5267@1|root,COG5267@2|Bacteria,2I8YT@201174|Actinobacteria,4DZU2@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158351_k127_1781014_1	1501230.ET33_12055	3.409e-62	242.0	COG4102@1|root,COG4102@2|Bacteria,1VDF3@1239|Firmicutes,4HV1I@91061|Bacilli,26W8X@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158351_k127_1781014_3	1123284.KB899046_gene2166	1.686e-25	110.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,26NJR@186821|Sporolactobacillaceae	91061|Bacilli	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_1817579_18	479434.Sthe_0152	2.274e-24	107.0	COG2132@1|root,COG2132@2|Bacteria,2G8IH@200795|Chloroflexi,27YH6@189775|Thermomicrobia	189775|Thermomicrobia	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
SRR25158351_k127_1817579_8	1229780.BN381_20132	1.53e-90	325.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,3UXHK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158351_k127_1817579_10	1229780.BN381_20133	9.947e-85	292.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,3UXS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158351_k127_1817579_13	1229780.BN381_50087	2.804e-60	222.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,3UWXI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158351_k127_1817579_4	1120936.KB907209_gene1792	7.146e-141	471.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
SRR25158351_k127_1817579_7	1038859.AXAU01000003_gene6061	7.119e-104	364.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,3JRYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158351_k127_1817579_1	1487953.JMKF01000072_gene3526	2.474e-212	668.0	COG0114@1|root,COG0114@2|Bacteria,1G0AD@1117|Cyanobacteria,1HI05@1150|Oscillatoriales	1117|Cyanobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158351_k127_1817579_11	33898.JRHJ01000069_gene7054	9.063e-73	256.0	COG1028@1|root,COG1028@2|Bacteria,2I41V@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1817579_3	1120950.KB892759_gene6228	9.962e-150	498.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DPPG@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158351_k127_1817579_0	469383.Cwoe_4566	1.831e-246	788.0	COG1164@1|root,COG1164@2|Bacteria,2IGPX@201174|Actinobacteria,4CPUP@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158351_k127_1817579_2	1229780.BN381_100026	3.938e-153	511.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,3UX0X@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2,Viral_helicase1
SRR25158351_k127_1817579_15	1313172.YM304_16840	1.489e-46	176.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158351_k127_1817579_20	1313172.YM304_35760	1.178e-15	89.0	COG0526@1|root,COG0526@2|Bacteria,2HA4Q@201174|Actinobacteria	201174|Actinobacteria	CO	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1817579_14	196162.Noca_0297	4.447e-53	193.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158351_k127_1817579_19	381666.H16_B0345	3.197e-17	92.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2VHTM@28216|Betaproteobacteria,1K1VF@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158351_k127_1817579_6	298654.FraEuI1c_3326	1.478e-123	406.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4EU68@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1817579_9	1146883.BLASA_4228	5.156e-87	296.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4ESNR@85013|Frankiales	201174|Actinobacteria	S	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_1817579_16	1089544.KB912942_gene1790	5.133e-45	167.0	2E8WU@1|root,3336Z@2|Bacteria,2GR5V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1817579_17	1150864.MILUP08_44786	1.702e-33	144.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4DB5P@85008|Micromonosporales	201174|Actinobacteria	I	Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158351_k127_1817579_12	1120949.KB903295_gene2386	1.882e-67	236.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158351_k127_1817579_5	1123320.KB889562_gene6786	5.899e-126	416.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158351_k127_1860264_26	1828.JOKB01000019_gene1441	6.543e-05	49.0	COG1073@1|root,COG1073@2|Bacteria,2GJE5@201174|Actinobacteria,4FUU6@85025|Nocardiaceae	201174|Actinobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRR25158351_k127_1860264_14	222534.KB893717_gene2176	4.461e-48	194.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
SRR25158351_k127_1860264_18	243160.BMAA1980	8.483e-34	147.0	COG2120@1|root,COG2120@2|Bacteria,1RI1F@1224|Proteobacteria,2VSXD@28216|Betaproteobacteria,1K4SZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_1860264_7	926569.ANT_24670	4.88e-121	409.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_1860264_22	1283299.AUKG01000003_gene359	1.96e-23	104.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_1860264_23	1283299.AUKG01000003_gene359	3.905e-20	95.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_1860264_2	471852.Tcur_3392	9.996e-157	513.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,4EFKQ@85012|Streptosporangiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158351_k127_1860264_17	1266908.AQPB01000031_gene1610	2.675e-42	176.0	COG0317@1|root,COG0317@2|Bacteria,1RKVU@1224|Proteobacteria,1SBBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Guanosine polyphosphate	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158351_k127_1860264_5	656024.FsymDg_0954	2.598e-147	477.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4EUMZ@85013|Frankiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158351_k127_1860264_8	1123320.KB889697_gene8996	2.855e-117	385.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1860264_3	1206726.BAFV01000033_gene2338	5.413e-151	488.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria,4FZEY@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1860264_21	1313172.YM304_14800	1.671e-26	119.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1860264_12	1123253.AUBD01000005_gene242	1.164e-75	267.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria,1X81A@135614|Xanthomonadales	135614|Xanthomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1860264_6	1313172.YM304_34050	5.909e-131	467.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	Cadherin,DUF11,GSu_C4xC__C2xCH,SdrD_B
SRR25158351_k127_1860264_9	1193181.BN10_690004	2.098e-92	310.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FFNS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1860264_1	253839.SSNG_06247	3.032e-185	587.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	adhC	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1860264_10	1944.JOAZ01000007_gene2153	1.836e-91	304.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,419X9@629295|Streptomyces griseus group	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_1860264_20	638303.Thal_0053	6.769e-29	131.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	ibrB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158351_k127_1860264_15	395961.Cyan7425_1325	1.18e-47	191.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158351_k127_1860264_11	1229780.BN381_360022	1.931e-90	317.0	COG1680@1|root,COG1680@2|Bacteria,2HEWU@201174|Actinobacteria,3UXIA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_1860264_0	314230.DSM3645_19883	8.963e-207	659.0	COG0069@1|root,COG0069@2|Bacteria,2J28V@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
SRR25158351_k127_1860264_4	1267535.KB906767_gene3263	1.217e-150	493.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158351_k127_1860264_19	1380370.JIBA01000002_gene2638	4.806e-31	126.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FF9M@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158351_k127_1860264_24	710685.MycrhN_2818	4.026e-16	91.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF3703,PAP2
SRR25158351_k127_1860264_13	1380393.JHVP01000005_gene3634	2.368e-74	268.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4EU4Q@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158351_k127_1860264_16	1123024.AUII01000052_gene3914	1.052e-44	163.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158351_k127_1869372_3	566461.SSFG_05137	1.617e-184	620.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158351_k127_1869372_5	525909.Afer_0246	1.883e-170	551.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CMPV@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158351_k127_1869372_18	1121422.AUMW01000025_gene297	2.803e-36	153.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,261JW@186807|Peptococcaceae	186801|Clostridia	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1869372_6	1229780.BN381_100019	1.246e-168	535.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1869372_7	44060.JODL01000024_gene284	4.42e-125	408.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	ppk2	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158351_k127_1869372_17	1283299.AUKG01000001_gene1512	1.862e-41	163.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria,4CR15@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158351_k127_1869372_25	1110697.NCAST_10_00860	8.444e-05	52.0	COG1403@1|root,COG2310@1|root,COG1403@2|Bacteria,COG2310@2|Bacteria,2GK6H@201174|Actinobacteria,4FY1D@85025|Nocardiaceae	201174|Actinobacteria	TV	HNH endonuclease	-	-	-	ko:K05792	-	-	-	-	ko00000	-	-	-	DUF2510,HNH,TerD
SRR25158351_k127_1869372_10	1122611.KB904007_gene7942	5.793e-80	281.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4EJUH@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158351_k127_1869372_11	1155718.KB891853_gene3700	1.791e-76	278.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_1869372_19	1229780.BN381_150120	1.001e-22	108.0	2FKUI@1|root,34CEY@2|Bacteria,2HCF2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1869372_8	1001240.GY21_08190	1.316e-100	351.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4FMAY@85023|Microbacteriaceae	201174|Actinobacteria	U	Type II/IV secretion system protein	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158351_k127_1869372_23	1229780.BN381_150122	7.355e-12	79.0	COG4965@1|root,COG4965@2|Bacteria,2HT3Y@201174|Actinobacteria,3UXMI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158351_k127_1869372_22	1313172.YM304_03590	1.197e-17	95.0	COG2064@1|root,COG2064@2|Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein F	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158351_k127_1869372_24	1340434.AXVA01000007_gene5143	1.913e-05	54.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,4HNWE@91061|Bacilli,1ZJ5U@1386|Bacillus	91061|Bacilli	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158351_k127_1869372_2	67352.JODS01000003_gene2182	1.489e-205	666.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria	201174|Actinobacteria	L	dead DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158351_k127_1869372_20	1125712.HMPREF1316_1492	4.111e-20	105.0	COG1316@1|root,COG1316@2|Bacteria,2HF18@201174|Actinobacteria,4CUEQ@84998|Coriobacteriia	84998|Coriobacteriia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158351_k127_1869372_21	471852.Tcur_1708	3.495e-19	101.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,4EJMR@85012|Streptosporangiales	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1869372_12	469371.Tbis_2286	8.675e-73	258.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DY80@85010|Pseudonocardiales	201174|Actinobacteria	P	overlaps another CDS with the same product name	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158351_k127_1869372_13	981369.JQMJ01000004_gene5399	2.325e-69	263.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,2NGQT@228398|Streptacidiphilus	201174|Actinobacteria	P	TrkA-C domain	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158351_k127_1869372_4	1229780.BN381_350018	6.066e-183	592.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,3UX33@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158351_k127_1869372_0	1229780.BN381_130116	5.948e-281	884.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,3UX5K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158351_k127_1869372_14	1173023.KE650771_gene5122	2.089e-58	214.0	COG0586@1|root,COG0586@2|Bacteria,1G4C6@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158351_k127_1869372_1	1205910.B005_2534	1.231e-280	891.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4EHDF@85012|Streptosporangiales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158351_k127_1869372_9	1229780.BN381_150140	1.79e-91	317.0	COG0477@1|root,COG0477@2|Bacteria,2I607@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3
SRR25158351_k127_1869372_15	1210046.B277_15349	5.861e-51	194.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4FG27@85021|Intrasporangiaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
SRR25158351_k127_1869372_16	1313172.YM304_03460	5.96e-44	175.0	COG0470@1|root,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	holB	-	2.7.7.7	ko:K02341,ko:K02343,ko:K09384	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158351_k127_1869372_26	710696.Intca_0960	0.0001727	48.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,4FJXN@85021|Intrasporangiaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Guanylate_cyc
SRR25158351_k127_1874489_3	1155714.KB891996_gene3476	8.982e-76	273.0	COG0248@1|root,COG1507@1|root,COG0248@2|Bacteria,COG1507@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158351_k127_1874489_6	1292020.H483_0116845	6.85e-13	74.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria	201174|Actinobacteria	S	Septum formation initiator family protein	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158351_k127_1874489_7	67257.JODR01000011_gene5510	8.037e-05	53.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria	201174|Actinobacteria	D	septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158351_k127_1874489_0	1229780.BN381_20129	6.163e-179	592.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,3UWCY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158351_k127_1874489_1	749414.SBI_00250	8.525e-126	416.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_1874489_4	1380356.JNIK01000005_gene893	6.902e-38	158.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1874489_2	1313172.YM304_33140	1.968e-112	387.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CN31@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
SRR25158351_k127_1874489_5	1472418.BBJC01000007_gene2626	6.621e-15	85.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidylprolyl isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
SRR25158351_k127_1893564_44	351607.Acel_1022	7.506e-51	187.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1893564_30	1304865.JAGF01000001_gene2446	2.826e-87	295.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1893564_12	656024.FsymDg_4119	9.739e-140	467.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4EUNB@85013|Frankiales	201174|Actinobacteria	S	AAA domain	-	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
SRR25158351_k127_1893564_3	398767.Glov_1814	1.052e-202	668.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,43S1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158351_k127_1893564_49	103733.JNYO01000022_gene6899	1.363e-40	162.0	COG2203@1|root,COG2203@2|Bacteria,2GNWV@201174|Actinobacteria,4EDTQ@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158351_k127_1893564_68	1206732.BAGD01000116_gene5183	0.0005	48.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FWY4@85025|Nocardiaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158351_k127_1893564_4	1173027.Mic7113_3556	3.083e-176	563.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1HG9W@1150|Oscillatoriales	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRR25158351_k127_1893564_42	298654.FraEuI1c_3328	2.364e-54	206.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_1893564_8	298654.FraEuI1c_3294	1.305e-169	550.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1893564_18	298654.FraEuI1c_3332	8.725e-116	409.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4EV2V@85013|Frankiales	201174|Actinobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_1893564_53	557599.MKAN_06020	2.943e-35	143.0	2B21F@1|root,31UIA@2|Bacteria,2GU1R@201174|Actinobacteria,23BK8@1762|Mycobacteriaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1893564_34	863365.XHC_1483	3.853e-72	254.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1X3TE@135614|Xanthomonadales	135614|Xanthomonadales	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158351_k127_1893564_62	235985.BBPN01000045_gene8094	1.532e-17	96.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,2NFDG@228398|Streptacidiphilus	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_1893564_14	469383.Cwoe_3764	1.887e-125	413.0	COG3239@1|root,COG3239@2|Bacteria,2IDCW@201174|Actinobacteria,4CSKP@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158351_k127_1893564_7	1232410.KI421414_gene2832	2.062e-170	548.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,43SYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158351_k127_1893564_66	1219035.NT2_01_05600	1.613e-05	51.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_1893564_59	1265310.CCBD010000062_gene1201	4.052e-27	115.0	2AU5M@1|root,31JSH@2|Bacteria,2IJSM@201174|Actinobacteria,239KJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1893564_32	487521.OCU_28310	3.812e-86	295.0	COG1028@1|root,COG1028@2|Bacteria,2HVB4@201174|Actinobacteria,23815@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1893564_20	298654.FraEuI1c_5558	2.896e-115	383.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1893564_43	298654.FraEuI1c_4191	3.062e-54	201.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1893564_1	298654.FraEuI1c_5559	1.655e-220	716.0	COG1804@1|root,COG1804@2|Bacteria,2GMGE@201174|Actinobacteria	201174|Actinobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1893564_51	298654.FraEuI1c_4189	1.59e-39	166.0	COG1545@1|root,COG1545@2|Bacteria,2GM2A@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
SRR25158351_k127_1893564_10	298654.FraEuI1c_4190	3.789e-155	506.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	ltp2	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
SRR25158351_k127_1893564_17	224325.AF_2100	1.189e-117	401.0	COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,245VB@183980|Archaeoglobi	28890|Euryarchaeota	E	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_1893564_54	1210046.B277_13644	1.466e-33	139.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria,4FJVE@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1893564_25	469383.Cwoe_3427	2.349e-98	351.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4CR2C@84995|Rubrobacteria	84995|Rubrobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158351_k127_1893564_28	487521.OCU_13380	8.564e-95	325.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,234HX@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	lipI	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158351_k127_1893564_39	1150599.MPHLEI_03733	6.124e-60	209.0	COG1545@1|root,COG1545@2|Bacteria,2IH6P@201174|Actinobacteria,23998@1762|Mycobacteriaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1893564_2	1150599.MPHLEI_03738	3.264e-216	675.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,234II@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	ltp1_1	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1893564_36	1160718.SU9_03666	1.273e-68	244.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
SRR25158351_k127_1893564_19	156889.Mmc1_1915	1.089e-115	389.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158351_k127_1893564_41	156889.Mmc1_1889	7.732e-57	207.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28,2.4.2.44	ko:K00772,ko:K19696	ko00270,ko01100,map00270,map01100	M00034	R01402,R09668	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
SRR25158351_k127_1893564_60	644283.Micau_5572	1.931e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,2IP48@201174|Actinobacteria,4DE61@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1893564_52	1306174.JODP01000029_gene3830	1.664e-37	148.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158351_k127_1893564_11	1123320.KB889562_gene6741	3.2e-146	471.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1893564_21	1160137.KB907307_gene3904	9.637e-113	370.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4FU5R@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158351_k127_1893564_61	675635.Psed_2271	6.128e-23	114.0	COG0454@1|root,COG0456@2|Bacteria,2I9PD@201174|Actinobacteria,4E9S5@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
SRR25158351_k127_1893564_13	1283283.ATXA01000007_gene3901	8.277e-129	432.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1893564_24	2002.JOEQ01000029_gene8203	1.691e-98	351.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4EM9F@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1893564_5	235985.BBPN01000019_gene5994	1.053e-172	570.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,2NGJB@228398|Streptacidiphilus	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	ltp3	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158351_k127_1893564_16	1303692.SFUL_323	6.852e-119	392.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158351_k127_1893564_50	208444.JNYY01000008_gene8427	9.235e-40	161.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4E22I@85010|Pseudonocardiales	201174|Actinobacteria	I	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1893564_45	253839.SSNG_00781	9.097e-50	194.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1893564_46	1313172.YM304_17800	1.175e-48	193.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158351_k127_1893564_57	886293.Sinac_2733	3.341e-29	134.0	COG1028@1|root,COG1028@2|Bacteria,2IYM6@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1893564_35	1123320.KB889585_gene1802	1.869e-69	243.0	COG1917@1|root,COG1917@2|Bacteria,2IDTH@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
SRR25158351_k127_1893564_67	561175.KB894095_gene2604	0.0001648	50.0	2EIQT@1|root,33CG7@2|Bacteria,2GWH9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1893564_29	1313172.YM304_20250	1.558e-87	302.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CN02@84992|Acidimicrobiia	84992|Acidimicrobiia	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158351_k127_1893564_26	521098.Aaci_1459	9.317e-98	332.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158351_k127_1893564_37	366394.Smed_2994	6.897e-65	227.0	COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,2U6UK@28211|Alphaproteobacteria,4BB31@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Phosphoglycerate mutase	gpmB1	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158351_k127_1893564_55	1382306.JNIM01000001_gene3765	3.408e-31	132.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158351_k127_1893564_22	1265505.ATUG01000002_gene1883	4.542e-109	365.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,42PFS@68525|delta/epsilon subdivisions,2WIR3@28221|Deltaproteobacteria,2MI8U@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
SRR25158351_k127_1893564_6	1169154.KB897789_gene357	8.364e-171	551.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	thiP	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1
SRR25158351_k127_1893564_31	1343740.M271_15645	2.3e-86	298.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	fbpC	-	-	ko:K02052,ko:K02062	ko02010,ko02024,map02010,map02024	M00191,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.19	-	-	ABC_tran,TOBE_2
SRR25158351_k127_1893564_65	1463903.JOIZ01000012_gene3240	3.866e-13	81.0	COG3409@1|root,COG3409@2|Bacteria,2I9HW@201174|Actinobacteria	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,PG_binding_1
SRR25158351_k127_1893564_23	1123320.KB889737_gene5381	1.721e-104	352.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_1893564_38	1262914.BN533_01538	6.094e-62	230.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H2XI@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158351_k127_1893564_63	745411.B3C1_04570	2.003e-14	85.0	COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria,1JB8C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	YhhN family	yhhN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	YhhN
SRR25158351_k127_1893564_56	1229780.BN381_110081	1.109e-29	134.0	COG1295@1|root,COG1295@2|Bacteria,2HZAF@201174|Actinobacteria,3UXPG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR25158351_k127_1893564_40	479434.Sthe_2419	7.966e-60	214.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,27Y9H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158351_k127_1893564_47	247633.GP2143_12926	7.836e-44	166.0	COG0346@1|root,COG0346@2|Bacteria,1R6IN@1224|Proteobacteria	1224|Proteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1893564_9	58123.JOFJ01000017_gene4192	2.011e-159	512.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4EFRM@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1893564_33	1313172.YM304_13810	5.403e-77	279.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_3544 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1893564_15	1122247.C731_4072	1.376e-122	411.0	COG1575@1|root,COG1575@2|Bacteria,2IPQ8@201174|Actinobacteria,23E29@1762|Mycobacteriaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158351_k127_1893564_58	1146883.BLASA_1857	3.712e-28	117.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158351_k127_1893564_48	1380347.JNII01000005_gene3882	1.68e-43	164.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4EVK6@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1893564_0	452637.Oter_2190	1.019e-240	764.0	COG1472@1|root,COG1472@2|Bacteria,46UPF@74201|Verrucomicrobia,3K900@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158351_k127_1893564_64	298653.Franean1_6925	5.873e-14	85.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1893564_27	469383.Cwoe_4738	4.884e-96	319.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4CQJ5@84995|Rubrobacteria	84995|Rubrobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158351_k127_1931797_1	1323361.JPOC01000021_gene2684	2.95e-157	504.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,4FUI9@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1931797_2	1323361.JPOC01000021_gene2683	3.639e-105	352.0	COG1545@1|root,COG1545@2|Bacteria,2GM2A@201174|Actinobacteria,4FX49@85025|Nocardiaceae	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,MaoC_dehydrat_N,OB_aCoA_assoc
SRR25158351_k127_1931797_3	1206726.BAFV01000006_gene313	8.252e-104	357.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,4FXAS@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1931797_9	1123320.KB889730_gene5894	1.492e-49	198.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_1931797_0	234621.RER_50730	8.15e-183	594.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,4FXPT@85025|Nocardiaceae	201174|Actinobacteria	I	Thiolase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
SRR25158351_k127_1931797_14	101510.RHA1_ro00019	3.09e-11	68.0	2EMYX@1|root,33FM2@2|Bacteria,2GZ6D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1931797_13	298654.FraEuI1c_7201	4.025e-15	88.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1931797_15	2074.JNYD01000020_gene2650	3.558e-07	60.0	29C55@1|root,2ZZ3Q@2|Bacteria,2HC01@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1931797_7	1112217.PPL19_01835	7.919e-64	229.0	COG1028@1|root,COG1028@2|Bacteria,1R7E3@1224|Proteobacteria,1RS7C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1931797_5	420324.KI912016_gene9421	3.598e-77	267.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4242,Guanylate_cyc
SRR25158351_k127_1931797_12	1206737.BAGF01000040_gene2327	5.385e-24	104.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4FW3Q@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1931797_10	1077972.ARGLB_083_00490	3.913e-34	136.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
SRR25158351_k127_1931797_8	1313172.YM304_41880	1.085e-54	217.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CNHT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1931797_6	653045.Strvi_6126	2.396e-70	263.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158351_k127_1931797_11	479432.Sros_7237	1.411e-31	133.0	COG4221@1|root,COG4221@2|Bacteria,2I3A4@201174|Actinobacteria,4EINW@85012|Streptosporangiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1931797_4	1283283.ATXA01000005_gene2026	2.574e-103	338.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4EVNB@85013|Frankiales	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158351_k127_1937596_12	298655.KI912266_gene2744	4.219e-176	559.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4EU8E@85013|Frankiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1937596_18	298655.KI912266_gene5041	6.139e-140	459.0	COG0318@1|root,COG0318@2|Bacteria,2I91U@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1937596_76	1123261.AXDW01000015_gene3372	3.103e-29	119.0	COG2146@1|root,COG2146@2|Bacteria,1RHEY@1224|Proteobacteria,1SA8F@1236|Gammaproteobacteria,1XAK1@135614|Xanthomonadales	135614|Xanthomonadales	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158351_k127_1937596_99	1121428.DESHY_160233___1	4.389e-05	46.0	2DR59@1|root,33A7S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1937596_51	710686.Mycsm_03169	1.803e-64	235.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_1937596_69	1041522.MCOL_V217038	1.097e-36	152.0	COG2030@1|root,COG2030@2|Bacteria,2IHT0@201174|Actinobacteria,2392X@1762|Mycobacteriaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_1937596_54	1122247.C731_4808	2.583e-55	207.0	COG2030@1|root,COG2030@2|Bacteria,2GN7T@201174|Actinobacteria,235VM@1762|Mycobacteriaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158351_k127_1937596_84	436229.JOEH01000008_gene4294	1.097e-21	100.0	COG5470@1|root,COG5470@2|Bacteria,2IR5P@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158351_k127_1937596_6	298654.FraEuI1c_3065	6.765e-261	815.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158351_k127_1937596_82	1230476.C207_06068	3.394e-25	111.0	COG5470@1|root,COG5470@2|Bacteria,1RBBV@1224|Proteobacteria,2U5CX@28211|Alphaproteobacteria,3JY7T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158351_k127_1937596_81	1313172.YM304_38500	2.582e-26	114.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR25158351_k127_1937596_53	1123242.JH636435_gene862	4.92e-57	218.0	COG1680@1|root,COG1680@2|Bacteria,2IZG3@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_1937596_38	1173023.KE650771_gene3940	7.382e-87	297.0	COG1881@1|root,COG1881@2|Bacteria,1G1EC@1117|Cyanobacteria	1117|Cyanobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
SRR25158351_k127_1937596_59	1158292.JPOE01000002_gene3050	5.939e-52	195.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,1KJ4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_1937596_62	1229780.BN381_330121	2.941e-50	205.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
SRR25158351_k127_1937596_5	99598.Cal7507_1154	2.568e-264	846.0	COG0243@1|root,COG0243@2|Bacteria,1G2SS@1117|Cyanobacteria,1HRPW@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
SRR25158351_k127_1937596_44	1449068.JMLQ01000004_gene1182	8.603e-77	266.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4FUZ4@85025|Nocardiaceae	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158351_k127_1937596_89	700508.D174_19245	1.561e-14	82.0	COG0746@1|root,COG0746@2|Bacteria,2IACX@201174|Actinobacteria,234SA@1762|Mycobacteriaceae	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158351_k127_1937596_66	33876.JNXY01000020_gene4470	2.332e-40	154.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4DJQN@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_1937596_79	867845.KI911784_gene3280	1.115e-27	118.0	COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi,375ZK@32061|Chloroflexia	32061|Chloroflexia	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158351_k127_1937596_102	1229780.BN381_60023	0.00025	45.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,3UXGT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
SRR25158351_k127_1937596_50	1078020.KEK_11463	3.748e-65	235.0	COG0673@1|root,COG0673@2|Bacteria,2HESE@201174|Actinobacteria,23736@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158351_k127_1937596_61	1123320.KB889683_gene2048	4.564e-51	197.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
SRR25158351_k127_1937596_71	110319.CF8_0220	4.225e-35	139.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4DQIS@85009|Propionibacteriales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158351_k127_1937596_100	1957.JODX01000032_gene6088	7.549e-05	48.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
SRR25158351_k127_1937596_55	298655.KI912266_gene4179	2.659e-55	212.0	COG2084@1|root,COG2084@2|Bacteria,2GUMJ@201174|Actinobacteria	201174|Actinobacteria	I	6-phosphogluconate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158351_k127_1937596_96	1120942.AUBM01000009_gene418	1.815e-05	49.0	2DRKZ@1|root,33C8D@2|Bacteria,2HM0Y@201174|Actinobacteria,4D65Y@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1937596_101	935866.JAER01000037_gene578	0.000133	53.0	COG2013@1|root,COG2013@2|Bacteria,2GSX6@201174|Actinobacteria,4DPJ8@85009|Propionibacteriales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF2510
SRR25158351_k127_1937596_93	1235793.C809_01971	8.693e-07	61.0	COG0297@1|root,COG0297@2|Bacteria,1UJZQ@1239|Firmicutes,25FFV@186801|Clostridia,27UFP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1937596_49	298653.Franean1_3676	2.488e-65	241.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_1937596_14	298653.Franean1_4038	3.553e-154	510.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158351_k127_1937596_36	298653.Franean1_4040	5.63e-89	318.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1937596_47	298655.KI912266_gene2618	9.54e-69	258.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria,4EVDG@85013|Frankiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158351_k127_1937596_31	298653.Franean1_2129	2.896e-104	361.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4ERX9@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1937596_17	1229780.BN381_330110	8.803e-143	479.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158351_k127_1937596_85	1169161.KB897715_gene5699	1.903e-21	101.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158351_k127_1937596_25	1313172.YM304_23420	3.148e-119	395.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CMVC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158351_k127_1937596_91	710111.FraQA3DRAFT_0235	1.566e-08	67.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1937596_2	515635.Dtur_1318	5.4e-323	1010.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158351_k127_1937596_98	319224.Sputcn32_2369	3.769e-05	55.0	COG1714@1|root,COG1714@2|Bacteria,1R6WK@1224|Proteobacteria,1RYVD@1236|Gammaproteobacteria,2Q9UI@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158351_k127_1937596_9	1313172.YM304_24260	4.079e-195	617.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CMWI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158351_k127_1937596_52	1313172.YM304_24220	2.223e-60	217.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CN8K@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158351_k127_1937596_32	525909.Afer_1266	2.592e-99	330.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158351_k127_1937596_56	479431.Namu_1639	2.601e-54	203.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4ESXC@85013|Frankiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRR25158351_k127_1937596_97	935548.KI912159_gene6126	2.135e-05	54.0	COG4454@1|root,COG4454@2|Bacteria,1N1PE@1224|Proteobacteria,2UCWF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SoxE
SRR25158351_k127_1937596_58	1313172.YM304_38640	3.869e-53	201.0	COG3336@1|root,COG3336@2|Bacteria,2HG9Q@201174|Actinobacteria,4CN83@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
SRR25158351_k127_1937596_95	479434.Sthe_1585	1.525e-05	53.0	2EKS3@1|root,33EFV@2|Bacteria,2GBBM@200795|Chloroflexi,27YP9@189775|Thermomicrobia	189775|Thermomicrobia	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
SRR25158351_k127_1937596_46	479434.Sthe_1584	4.428e-73	255.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi,27YE2@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158351_k127_1937596_11	562970.Btus_0433	2.639e-178	578.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,2782I@186823|Alicyclobacillaceae	91061|Bacilli	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.10.3.12,1.9.3.1	ko:K02274,ko:K02827	ko00190,ko01100,map00190,map01100	M00155,M00416	R00081,R09492	RC00016,RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158351_k127_1937596_45	479434.Sthe_1582	4.539e-74	265.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158351_k127_1937596_40	1120972.AUMH01000001_gene1263	2.34e-83	286.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,2788K@186823|Alicyclobacillaceae	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158351_k127_1937596_28	1254432.SCE1572_36775	4.763e-112	385.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158351_k127_1937596_78	390989.JOEG01000030_gene1717	7.181e-28	127.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4DCVM@85008|Micromonosporales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158351_k127_1937596_23	106370.Francci3_1267	2.193e-121	400.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4ERQ7@85013|Frankiales	201174|Actinobacteria	T	PFAM PhoH family protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158351_k127_1937596_67	1229780.BN381_80274	7.418e-38	147.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158351_k127_1937596_77	502025.Hoch_0097	2.44e-28	124.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,42R1A@68525|delta/epsilon subdivisions,2WMV6@28221|Deltaproteobacteria,2YVVD@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158351_k127_1937596_26	1229780.BN381_80272	1.721e-115	389.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,3UWDM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_1937596_41	1313172.YM304_21110	2.98e-83	288.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CN2R@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158351_k127_1937596_27	1313172.YM304_21150	8.849e-115	383.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_1937596_92	1463820.JOGW01000016_gene5095	2.762e-07	64.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158351_k127_1937596_57	1229780.BN381_450068	8.515e-54	202.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,3UWW2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	ECF sigma factor	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158351_k127_1937596_22	1313172.YM304_30920	1.066e-122	408.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1937596_103	710111.FraQA3DRAFT_3199	0.0008199	48.0	2B2W0@1|root,31VGI@2|Bacteria,2GVMP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1937596_4	1229780.BN381_80270	1.138e-270	847.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,3UWA1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158351_k127_1937596_88	1229780.BN381_80262	4.608e-18	87.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,3UWXJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158351_k127_1937596_75	1229780.BN381_10276	2.537e-31	141.0	COG1466@1|root,COG1466@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
SRR25158351_k127_1937596_39	1121877.JQKF01000015_gene76	1.034e-86	296.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CNF4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158351_k127_1937596_63	1313172.YM304_21020	1.23e-48	198.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria	201174|Actinobacteria	L	ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158351_k127_1937596_70	1278308.KB907077_gene1873	2.276e-36	149.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4FPAM@85023|Microbacteriaceae	201174|Actinobacteria	L	SLBB domain	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158351_k127_1937596_0	644283.Micau_4485	0.0	1311.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4DAJQ@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158351_k127_1937596_48	1380354.JIAN01000005_gene2477	1.879e-65	233.0	COG0118@1|root,COG0118@2|Bacteria,2IKEE@201174|Actinobacteria	201174|Actinobacteria	E	Glutamine amidotransferase class-I	-	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158351_k127_1937596_29	1288083.AUKR01000075_gene415	6.844e-106	355.0	COG0107@1|root,COG0107@2|Bacteria,2GJEY@201174|Actinobacteria	201174|Actinobacteria	E	Dihydrouridine synthase (Dus)	-	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
SRR25158351_k127_1937596_83	1463857.JOFZ01000015_gene806	1.675e-22	106.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158351_k127_1937596_64	1229780.BN381_10238	1.094e-42	170.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,3UWJW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158351_k127_1937596_80	1313172.YM304_19200	4.458e-27	125.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	sdaAB	-	2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19	ko:K01139,ko:K01752,ko:K01754	ko00230,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00336,R00429,R00590,R00996	RC00002,RC00078,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	ACT,HD_4,PALP,RelA_SpoT,SDH_beta
SRR25158351_k127_1937596_16	1463926.JOCA01000001_gene4620	8.229e-148	480.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158351_k127_1937596_73	1440774.Y900_019020	2.672e-32	148.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158351_k127_1937596_7	234267.Acid_5780	3.458e-217	727.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
SRR25158351_k127_1937596_8	1313172.YM304_23520	2.437e-196	622.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,4CMU1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158351_k127_1937596_30	1193181.BN10_30019	7.779e-106	351.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4FE30@85021|Intrasporangiaceae	201174|Actinobacteria	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158351_k127_1937596_20	1048339.KB913029_gene4847	7.536e-134	442.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4ERK4@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
SRR25158351_k127_1937596_68	1229780.BN381_330108	2.197e-37	147.0	COG0073@1|root,COG0073@2|Bacteria,2IQBN@201174|Actinobacteria	201174|Actinobacteria	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
SRR25158351_k127_1937596_34	1313172.YM304_23440	2.842e-97	344.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CMY3@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158351_k127_1937596_15	1229780.BN381_10207	6.834e-148	479.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,3UWET@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158351_k127_1937596_74	164757.Mjls_3554	8.519e-32	126.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,23AQ6@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158351_k127_1937596_72	1229780.BN381_80103	1.307e-32	130.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,3UWVG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158351_k127_1937596_13	1313172.YM304_18440	2.703e-172	573.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CMPW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribonuclease E/G family	-	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
SRR25158351_k127_1937596_65	1313172.YM304_18430	5.976e-42	169.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158351_k127_1937596_3	1313172.YM304_18420	3.042e-301	937.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_1937596_43	1120936.KB907209_gene1853	3.595e-82	295.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4EFT6@85012|Streptosporangiales	201174|Actinobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_1937596_35	1137268.AZXF01000007_gene4035	7.032e-93	344.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4EHIA@85012|Streptosporangiales	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
SRR25158351_k127_1937596_21	717605.Theco_3788	1.411e-127	426.0	COG3653@1|root,COG3653@2|Bacteria,1TSGD@1239|Firmicutes,4HBQ4@91061|Bacilli,26VUM@186822|Paenibacillaceae	91061|Bacilli	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158351_k127_1937596_90	1121423.JONT01000001_gene1922	3.406e-10	67.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24RP5@186801|Clostridia,262R9@186807|Peptococcaceae	186801|Clostridia	M	shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158351_k127_1937596_87	1229780.BN381_80096	4.086e-18	97.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158351_k127_1937596_19	561175.KB894104_gene1149	1.571e-136	452.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4EFPD@85012|Streptosporangiales	201174|Actinobacteria	D	Actin	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158351_k127_1937596_60	1313172.YM304_18350	2.348e-51	190.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CN6F@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158351_k127_1937596_33	1313172.YM304_18330	8.519e-99	341.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CNAR@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
SRR25158351_k127_1937596_1	106370.Francci3_1314	0.0	1185.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4ERSS@85013|Frankiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158351_k127_1937596_10	479433.Caci_7293	6.942e-189	608.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158351_k127_1937596_37	525909.Afer_0762	1.482e-87	304.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158351_k127_1937596_42	1313172.YM304_18300	1.448e-82	293.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CN55@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
SRR25158351_k127_1937596_24	68570.DC74_1076	3.49e-120	396.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158351_k127_1937596_86	208444.JNYY01000001_gene5507	1.543e-20	94.0	COG4968@1|root,COG4968@2|Bacteria,2GTH1@201174|Actinobacteria	201174|Actinobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158351_k127_1939838_15	1121877.JQKF01000004_gene1129	5.187e-55	214.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CMZX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158351_k127_1939838_2	1313172.YM304_27440	1.667e-121	402.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CMRC@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158351_k127_1939838_17	1229780.BN381_330055	2.802e-51	205.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,3UWMF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158351_k127_1939838_13	1171373.PACID_22040	1.613e-59	213.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4DNKY@85009|Propionibacteriales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158351_k127_1939838_7	1120972.AUMH01000011_gene192	3.274e-88	301.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,278X5@186823|Alicyclobacillaceae	91061|Bacilli	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
SRR25158351_k127_1939838_12	1313172.YM304_27480	1.232e-62	231.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CMXN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158351_k127_1939838_4	1229780.BN381_330051	2.786e-102	345.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,3UWBA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158351_k127_1939838_33	1894.JOER01000002_gene3586	2.754e-06	60.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158351_k127_1939838_28	1380347.JNII01000007_gene766	1.366e-18	100.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4ET1M@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158351_k127_1939838_5	351607.Acel_1546	4.928e-89	301.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4ERYG@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1939838_19	1298865.H978DRAFT_2755	8.58e-48	184.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG4974 Site-specific recombinase XerD	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158351_k127_1939838_3	446471.Xcel_1176	4.719e-118	400.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4F38C@85017|Promicromonosporaceae	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158351_k127_1939838_18	266117.Rxyl_1396	6.457e-51	207.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria	84995|Rubrobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158351_k127_1939838_31	83332.Rv1322	1.084e-12	76.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,23AST@1762|Mycobacteriaceae	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1939838_23	1206735.BAGG01000092_gene3752	6.919e-32	128.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4G1R8@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158351_k127_1939838_20	1120950.KB892769_gene5386	1.089e-43	160.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4DR0E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158351_k127_1939838_16	28042.GU90_17700	1.026e-52	188.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158351_k127_1939838_8	1229780.BN381_330038	4.864e-87	294.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,3UWGW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158351_k127_1939838_22	1229780.BN381_330037	1.564e-39	154.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,3UWUH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158351_k127_1939838_32	1410650.JHWL01000002_gene3200	3.639e-09	67.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,4BZVE@830|Butyrivibrio	186801|Clostridia	S	KH domain	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158351_k127_1939838_26	485913.Krac_1372	5.53e-24	118.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158351_k127_1939838_1	913865.DOT_3495	7.674e-155	502.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2610F@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158351_k127_1939838_6	1313172.YM304_18700	6.109e-89	306.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CMY6@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54
SRR25158351_k127_1939838_10	1313172.YM304_22030	6.288e-69	261.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158351_k127_1939838_0	1313172.YM304_18690	1.421e-258	829.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CMQE@84992|Acidimicrobiia	84992|Acidimicrobiia	D	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
SRR25158351_k127_1939838_27	1032480.MLP_45760	1.878e-23	103.0	COG1254@1|root,COG1254@2|Bacteria,2HZEW@201174|Actinobacteria,4DSGP@85009|Propionibacteriales	201174|Actinobacteria	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158351_k127_1939838_11	1313172.YM304_18680	1.183e-62	229.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CN5C@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158351_k127_1939838_14	1313172.YM304_18670	9.266e-59	216.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CN7Y@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158351_k127_1939838_25	1313172.YM304_18660	3.927e-27	115.0	COG0236@1|root,COG0236@2|Bacteria,2HG9V@201174|Actinobacteria,4CN8D@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158351_k127_1939838_9	1313172.YM304_18650	2.303e-74	269.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CMRM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158351_k127_1939838_30	700015.Corgl_1055	1.621e-17	84.0	COG0333@1|root,COG0333@2|Bacteria,2HU2H@201174|Actinobacteria,4CWMX@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158351_k127_1939838_29	1229780.BN381_330015	1.18e-17	94.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,3UWUU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158351_k127_1939838_24	525909.Afer_1513	1.134e-31	130.0	COG0711@1|root,COG0711@2|Bacteria,2HG9T@201174|Actinobacteria,4CN89@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1939838_21	1123023.JIAI01000006_gene245	6.625e-40	150.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4E33S@85010|Pseudonocardiales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158351_k127_1953105_0	1123320.KB889686_gene721	4.67e-129	428.0	COG0318@1|root,COG0318@2|Bacteria,2IE11@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1953105_4	656024.FsymDg_2661	9.109e-50	203.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_1953105_1	1206731.BAGB01000047_gene5182	9.692e-117	402.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4FTYC@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158351_k127_1953105_3	1157632.AQWQ01000001_gene5900	3.173e-55	203.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1953105_2	222534.KB893715_gene1705	4.284e-75	261.0	COG3845@1|root,COG3845@2|Bacteria	2|Bacteria	P	ABC transporter	-	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1953603_8	1123320.KB889717_gene7662	1.011e-134	446.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_1953603_0	1267535.KB906767_gene3159	0.0	1289.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria,2JIVQ@204432|Acidobacteriia	204432|Acidobacteriia	L	dead deah	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158351_k127_1953603_10	1408433.JHXV01000002_gene442	8.225e-98	348.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
SRR25158351_k127_1953603_23	66373.JOFQ01000005_gene3835	4.9e-08	59.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158351_k127_1953603_22	1313172.YM304_41810	6.8e-11	71.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4CNUT@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1953603_25	1380356.JNIK01000006_gene1413	0.0001485	52.0	COG1028@1|root,COG1028@2|Bacteria	1380356.JNIK01000006_gene1413|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1953603_18	397278.JOJN01000001_gene3060	2.172e-55	212.0	2C3PP@1|root,2Z954@2|Bacteria,2IB93@201174|Actinobacteria,4DWUY@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1953603_4	1283299.AUKG01000002_gene4485	7.185e-158	519.0	COG2267@1|root,COG2267@2|Bacteria,2I41Z@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1953603_3	1121106.JQKB01000016_gene5351	1.572e-182	588.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_3
SRR25158351_k127_1953603_6	43989.cce_4003	3.134e-151	493.0	COG0367@1|root,COG0367@2|Bacteria,1FZZS@1117|Cyanobacteria,3KKRM@43988|Cyanothece	1117|Cyanobacteria	E	Aluminium induced protein	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158351_k127_1953603_13	1463936.JOJI01000004_gene2653	4.369e-71	251.0	2DBIF@1|root,2Z9FG@2|Bacteria,2I9FF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1953603_16	195253.Syn6312_2317	1.499e-58	213.0	COG1216@1|root,COG1216@2|Bacteria,1GHGM@1117|Cyanobacteria,1H449@1129|Synechococcus	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_1953603_24	765698.Mesci_0405	6.728e-06	58.0	2DECI@1|root,32U34@2|Bacteria,1NQ9C@1224|Proteobacteria,2VGBM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158351_k127_1953603_19	671143.DAMO_2981	2.671e-33	148.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
SRR25158351_k127_1953603_14	671143.DAMO_2983	6.09e-63	234.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	2.4.1.11,2.4.1.345	ko:K08256,ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292,R11702	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1953603_17	216594.MMAR_0286	1.157e-55	211.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158351_k127_1953603_9	1341646.CBMO010000079_gene385	1.94e-109	371.0	COG3618@1|root,COG3618@2|Bacteria,2GM2D@201174|Actinobacteria,23C3F@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1953603_7	1341646.CBMO010000079_gene386	5.111e-148	509.0	COG1028@1|root,COG1028@2|Bacteria,2IF3A@201174|Actinobacteria,23CSF@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1953603_2	1341646.CBMO010000079_gene387	3.291e-232	752.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,23CYC@1762|Mycobacteriaceae	201174|Actinobacteria	P	NAD(P)-binding Rossmann-like domain	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
SRR25158351_k127_1953603_5	1183377.Py04_0863	1.674e-156	506.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158351_k127_1953603_11	497965.Cyan7822_3387	3.704e-96	323.0	COG0549@1|root,COG0549@2|Bacteria,1GAQG@1117|Cyanobacteria,3KJ7G@43988|Cyanothece	1117|Cyanobacteria	E	Belongs to the carbamate kinase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158351_k127_1953603_1	525909.Afer_0713	0.0	1155.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4CMQ1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158351_k127_1953603_20	929712.KI912613_gene218	7.865e-33	144.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	-	2.7.13.3	ko:K02484,ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_1953603_15	1089545.KB913037_gene1469	5.124e-62	222.0	COG0745@1|root,COG0745@2|Bacteria,2ICHY@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1953603_12	710111.FraQA3DRAFT_3282	4.959e-74	258.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158351_k127_1963791_1	1229780.BN381_290032	2.432e-232	732.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_1963791_18	502025.Hoch_2518	2.717e-96	329.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_1963791_7	1123320.KB889702_gene9490	4.313e-160	521.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	dapC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1963791_14	224325.AF_1815	1.793e-109	368.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,24610@183980|Archaeoglobi	28890|Euryarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_1963791_21	67267.JNXT01000038_gene3373	3.507e-74	260.0	2BWNB@1|root,32WFI@2|Bacteria,2IAXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1963791_17	477641.MODMU_0856	9.075e-100	351.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158351_k127_1963791_35	298655.KI912266_gene5760	1.982e-08	61.0	COG2030@1|root,COG2030@2|Bacteria,2H7MB@201174|Actinobacteria,4ES36@85013|Frankiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158351_k127_1963791_19	710685.MycrhN_6188	1.082e-93	319.0	COG1024@1|root,COG1024@2|Bacteria,2IDF4@201174|Actinobacteria,236SJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158351_k127_1963791_6	298655.KI912266_gene5762	7.792e-176	562.0	COG1960@1|root,COG1960@2|Bacteria,2IBE0@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1963791_16	487521.OCU_19420	9.678e-101	334.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,238FA@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1963791_12	2002.JOEQ01000015_gene5076	2.022e-129	417.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,4EK30@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_1963791_10	710685.MycrhN_6192	1.855e-141	467.0	COG0318@1|root,COG0318@2|Bacteria,2IBED@201174|Actinobacteria,2370C@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1963791_23	1048339.KB913029_gene4145	1.012e-61	229.0	28HG7@1|root,32T0H@2|Bacteria,2IFQ1@201174|Actinobacteria,4EVYV@85013|Frankiales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_1963791_25	211165.AJLN01000116_gene2992	2.497e-47	179.0	COG0500@1|root,COG2226@2|Bacteria,1G96Z@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1963791_2	298655.KI912266_gene4993	1.062e-215	687.0	COG0683@1|root,COG0683@2|Bacteria,2IAAV@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1963791_13	1464048.JNZS01000025_gene780	2.509e-122	409.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4DA91@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158351_k127_1963791_9	711393.AYRX01000024_gene1463	1.481e-146	476.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
SRR25158351_k127_1963791_27	1380354.JIAN01000008_gene3447	2.477e-24	113.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4F2WM@85016|Cellulomonadaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158351_k127_1963791_32	1283283.ATXA01000008_gene3145	2.648e-11	70.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CP12
SRR25158351_k127_1963791_4	298655.KI912266_gene2744	3.212e-180	571.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4EU8E@85013|Frankiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1963791_5	1123320.KB889747_gene7183	8.294e-178	568.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1963791_33	1380390.JIAT01000009_gene1188	1.011e-10	66.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4CRV8@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1963791_24	1463887.KL589989_gene2186	9.244e-57	203.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158351_k127_1963791_8	1123320.KB889747_gene7182	1.332e-151	490.0	COG1804@1|root,COG1804@2|Bacteria,2GMJ9@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1963791_0	1210908.HSB1_39720	4.19e-271	854.0	COG3119@1|root,arCOG02791@2157|Archaea,2Y8G8@28890|Euryarchaeota,23VJY@183963|Halobacteria	183963|Halobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158351_k127_1963791_31	749414.SBI_06902	3.082e-12	78.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158351_k127_1963791_15	269799.Gmet_2332	5.938e-104	349.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N6P@68525|delta/epsilon subdivisions,2WJVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158351_k127_1963791_29	68223.JNZY01000010_gene1909	9.281e-19	100.0	COG0110@1|root,COG0110@2|Bacteria,2IDUP@201174|Actinobacteria	201174|Actinobacteria	GM	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158351_k127_1963791_22	247634.GPB2148_643	9.044e-74	264.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1J5AK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG0657 Esterase lipase	aes	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
SRR25158351_k127_1963791_20	1211815.CBYP010000014_gene3514	5.558e-76	267.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158351_k127_1963791_11	298655.KI912266_gene6479	7.975e-134	437.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4ERDJ@85013|Frankiales	201174|Actinobacteria	C	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_1963791_30	1380390.JIAT01000009_gene379	1.235e-18	91.0	COG3794@1|root,COG3794@2|Bacteria,2HP9P@201174|Actinobacteria,4CQMV@84995|Rubrobacteria	84995|Rubrobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158351_k127_1963791_3	1123320.KB889585_gene1796	2.014e-183	581.0	COG1804@1|root,COG1804@2|Bacteria,2I8ZJ@201174|Actinobacteria	201174|Actinobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_1963791_26	1283299.AUKG01000005_gene92	1.316e-25	110.0	COG0496@1|root,COG0496@2|Bacteria,2IRBR@201174|Actinobacteria	201174|Actinobacteria	S	Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158351_k127_1966845_6	1394178.AWOO02000010_gene4128	1.363e-80	291.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4EPWP@85012|Streptosporangiales	201174|Actinobacteria	I	Carboxylesterase family	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158351_k127_1966845_4	1206720.BAFQ01000109_gene2696	7.276e-94	316.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4FY27@85025|Nocardiaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	rifO	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_1966845_15	1380356.JNIK01000001_gene2171	1.317e-17	97.0	COG0683@1|root,COG0683@2|Bacteria,2HTW3@201174|Actinobacteria,4EV25@85013|Frankiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_1966845_1	298655.KI912266_gene2620	1.971e-125	435.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
SRR25158351_k127_1966845_5	298653.Franean1_4040	9.949e-93	312.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1966845_8	298653.Franean1_4041	6.112e-76	276.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158351_k127_1966845_14	298654.FraEuI1c_3299	3.383e-24	111.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	ydgC	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1966845_13	298654.FraEuI1c_2852	1.427e-37	148.0	COG2030@1|root,COG2030@2|Bacteria,2IRY8@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_1966845_10	1415779.JOMH01000001_gene676	3.756e-68	245.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria,1X4R1@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_1966845_17	1449050.JNLE01000003_gene1931	1.384e-05	55.0	COG1082@1|root,COG1082@2|Bacteria,1VG3T@1239|Firmicutes,24QK1@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158351_k127_1966845_11	298655.KI912266_gene6128	1.804e-63	241.0	COG3845@1|root,COG3845@2|Bacteria,2I5UR@201174|Actinobacteria,4EX5R@85013|Frankiales	201174|Actinobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1966845_9	285535.JOEY01000056_gene6752	3.093e-69	266.0	COG3845@1|root,COG3845@2|Bacteria,2I5SB@201174|Actinobacteria	201174|Actinobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_1966845_0	1283283.ATXA01000001_gene1189	7.121e-137	458.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU9P@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158351_k127_1966845_7	365528.KB891170_gene5159	1.995e-78	278.0	COG0683@1|root,COG0683@2|Bacteria,2HU22@201174|Actinobacteria,4EWHZ@85013|Frankiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1966845_3	298654.FraEuI1c_3325	2.072e-112	391.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1966845_12	298655.KI912266_gene2733	3.296e-61	222.0	COG1028@1|root,COG1028@2|Bacteria,2H3HS@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1966845_2	1122247.C731_4797	1.065e-124	412.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria,232W0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_1966845_16	931627.MycrhDRAFT_6073	7.628e-09	65.0	2B0NY@1|root,31T0Q@2|Bacteria,2ICKX@201174|Actinobacteria,237U9@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_253010_14	1229780.BN381_290032	5.882e-71	246.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_253010_3	58123.JOFJ01000008_gene498	1.518e-129	426.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4ENGU@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_253010_13	479432.Sros_1182	3.7e-76	267.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria,4EQQ9@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_253010_12	105422.BBPM01000026_gene4151	1.995e-76	269.0	COG5031@1|root,COG5031@2|Bacteria,2IF2J@201174|Actinobacteria,2NHXK@228398|Streptacidiphilus	201174|Actinobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_253010_23	1068978.AMETH_4476	1.919e-06	58.0	2E3SC@1|root,32YPX@2|Bacteria,2HPCF@201174|Actinobacteria,4E4BJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158351_k127_253010_6	405948.SACE_3524	2.056e-107	364.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DYBA@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_253010_0	1380347.JNII01000005_gene3218	8.744e-193	612.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4ETMT@85013|Frankiales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158351_k127_253010_5	73044.JNXP01000013_gene1364	2.014e-109	364.0	COG1294@1|root,COG3476@1|root,COG1294@2|Bacteria,COG3476@2|Bacteria,2GN42@201174|Actinobacteria	201174|Actinobacteria	C	oxidase, subunit	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158351_k127_253010_16	543632.JOJL01000027_gene2801	2.22e-53	192.0	2DMC7@1|root,32J0V@2|Bacteria,2I81N@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158351_k127_253010_1	298655.KI912266_gene4987	6.424e-191	602.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4ETPN@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_253010_7	1211815.CBYP010000048_gene1670	2.732e-103	371.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158351_k127_253010_24	448385.sce7448	4.033e-06	60.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria,2YWGV@29|Myxococcales	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158351_k127_253010_4	365528.KB891213_gene2458	3.717e-126	427.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158351_k127_253010_21	1380370.JIBA01000017_gene2961	5.054e-16	86.0	COG0344@1|root,COG0344@2|Bacteria,2IF8Y@201174|Actinobacteria,4FG1E@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158351_k127_253010_10	1120936.KB907221_gene2141	5.918e-83	290.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_253010_19	1043493.BBLU01000002_gene1783	2.013e-30	133.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria	201174|Actinobacteria	S	DegV family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158351_k127_253010_20	561175.KB894101_gene4560	7.581e-21	104.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,4EI2H@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158351_k127_253010_11	1122247.C731_3144	6.964e-82	279.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,233VA@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM inositol monophosphatase	cysQ_1	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158351_k127_253010_9	1415166.NONO_c57770	3.965e-98	341.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4FU1Y@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158351_k127_253010_8	566461.SSFG_05994	9.171e-100	342.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria	201174|Actinobacteria	P	Molybdate ABC transporter	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR25158351_k127_253010_17	1158050.KB895453_gene849	3.138e-48	188.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,1W9B5@1268|Micrococcaceae	201174|Actinobacteria	P	molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158351_k127_253010_18	656024.FsymDg_3138	4.228e-41	156.0	COG0789@1|root,COG3585@1|root,COG0789@2|Bacteria,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158351_k127_253010_2	1121877.JQKF01000016_gene124	3.068e-189	597.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CMRQ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_253010_15	469383.Cwoe_3837	1.261e-62	222.0	COG1024@1|root,COG1024@2|Bacteria,2I8WN@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA3	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_253010_22	706587.Desti_5013	1.081e-12	73.0	COG5513@1|root,COG5513@2|Bacteria,1Q83W@1224|Proteobacteria,42XPU@68525|delta/epsilon subdivisions,2WT8K@28221|Deltaproteobacteria,2MQR1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Chagasin family peptidase inhibitor I42	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Inhibitor_I42
SRR25158351_k127_280717_6	298655.KI912266_gene5567	1.388e-42	159.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_280717_3	1123320.KB889696_gene9134	2.631e-137	445.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
SRR25158351_k127_280717_2	298654.FraEuI1c_1893	1.043e-188	598.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158351_k127_280717_4	1283283.ATXA01000014_gene3564	1.797e-102	350.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria,4ETUF@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_280717_1	1298864.AUEQ01000003_gene5843	2.667e-211	685.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,234BA@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_280717_5	452652.KSE_04175	7.709e-52	205.0	COG3170@1|root,COG3170@2|Bacteria,2H5I1@201174|Actinobacteria,2M58V@2063|Kitasatospora	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_280717_8	1120944.JONS01000096_gene2	9.326e-14	84.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4D58M@85005|Actinomycetales	201174|Actinobacteria	V	the current gene model (or a revised gene model) may contain a frame shift	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_280717_0	1298863.AUEP01000022_gene1864	8.165e-224	709.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2ID98@201174|Actinobacteria,4DQDB@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
SRR25158351_k127_280717_7	1298863.AUEP01000022_gene1862	7.565e-35	140.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria,4DV53@85009|Propionibacteriales	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158351_k127_280717_9	1192034.CAP_5082	8.534e-08	64.0	COG3055@1|root,COG5184@1|root,COG3055@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2Z3A7@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
SRR25158351_k127_305288_27	1229780.BN381_70018	6.883e-81	281.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,3UWBG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell cycle protein	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_305288_49	926554.KI912662_gene1249	4.137e-52	200.0	COG0631@1|root,COG0631@2|Bacteria,1WIBX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158351_k127_305288_62	710687.KI912270_gene5219	1.879e-16	85.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,232PU@1762|Mycobacteriaceae	201174|Actinobacteria	T	FHA domain-containing protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158351_k127_305288_41	1229780.BN381_70015	2.519e-65	231.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,3UWPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158351_k127_305288_47	64471.sync_1534	1.276e-54	207.0	COG5031@1|root,COG5031@2|Bacteria,1GQ8D@1117|Cyanobacteria,1H069@1129|Synechococcus	1117|Cyanobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_305288_39	1255043.TVNIR_1705	1.377e-66	241.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_305288_44	710111.FraQA3DRAFT_1741	2.734e-57	203.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4ESRX@85013|Frankiales	201174|Actinobacteria	O	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158351_k127_305288_61	314345.SPV1_01522	2.995e-21	102.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria	1224|Proteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158351_k127_305288_4	886293.Sinac_2020	4.194e-177	567.0	COG0364@1|root,COG0364@2|Bacteria,2IYER@203682|Planctomycetes	203682|Planctomycetes	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158351_k127_305288_10	1210884.HG799464_gene10383	3.67e-150	498.0	COG1023@1|root,COG1023@2|Bacteria,2IYCD@203682|Planctomycetes	203682|Planctomycetes	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158351_k127_305288_21	1469245.JFBG01000016_gene949	2.847e-92	309.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,1S0A5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158351_k127_305288_20	1313172.YM304_02490	2.206e-93	315.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158351_k127_305288_15	1246445.ANAY01000039_gene761	6.947e-103	350.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4EH2Z@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158351_k127_305288_9	929712.KI912613_gene3286	4.698e-153	500.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CPM9@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158351_k127_305288_32	221288.JH992901_gene2456	7.31e-78	277.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria,1JIE9@1189|Stigonemataceae	1117|Cyanobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158351_k127_305288_14	58123.JOFJ01000005_gene1508	1.27e-115	394.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria,4EGUG@85012|Streptosporangiales	201174|Actinobacteria	E	Helix-hairpin-helix domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRR25158351_k127_305288_50	1192124.LIG30_4793	1.777e-51	190.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2VICR@28216|Betaproteobacteria,1K078@119060|Burkholderiaceae	28216|Betaproteobacteria	H	PFAM Dimethylmenaquinone methyltransferase	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR25158351_k127_305288_23	266117.Rxyl_0619	2.393e-91	310.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_305288_59	469383.Cwoe_5005	2.113e-31	128.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K03490	-	-	-	-	ko00000,ko03000	-	-	-	Cupin_2
SRR25158351_k127_305288_45	1370121.AUWS01000052_gene1663	4.543e-56	210.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria,234I1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158351_k127_305288_63	1385519.N801_04810	1.365e-14	82.0	2EHZA@1|root,33BQS@2|Bacteria,2IJZ0@201174|Actinobacteria,4FGP6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_305288_65	996637.SGM_4719	6.644e-10	72.0	2E45J@1|root,32Z1K@2|Bacteria,2GR89@201174|Actinobacteria	201174|Actinobacteria	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158351_k127_305288_51	1463825.JNXC01000022_gene538	3.516e-50	186.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4E35S@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158351_k127_305288_24	1206730.BAGA01000057_gene2539	4.873e-90	315.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,4FV06@85025|Nocardiaceae	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158351_k127_305288_53	1172181.KB911701_gene1052	2.266e-47	175.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158351_k127_305288_35	644283.Micau_0415	1.482e-74	261.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,4D94C@85008|Micromonosporales	201174|Actinobacteria	S	RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
SRR25158351_k127_305288_58	1380354.JIAN01000008_gene3444	8.251e-32	134.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2I4P8@201174|Actinobacteria	201174|Actinobacteria	U	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158351_k127_305288_67	1123024.AUII01000015_gene3739	4.205e-08	67.0	COG5646@1|root,COG5646@2|Bacteria,2I3RY@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158351_k127_305288_12	1045009.AFXQ01000009_gene741	6.38e-137	445.0	COG3392@1|root,COG3392@2|Bacteria,2IBCB@201174|Actinobacteria	201174|Actinobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
SRR25158351_k127_305288_60	1229780.BN381_130122	2.545e-31	137.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRR25158351_k127_305288_34	667632.KB890167_gene1596	7.359e-75	255.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,1K08S@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR25158351_k127_305288_57	237368.SCABRO_02095	5.507e-33	134.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,PDZ_2,Polyketide_cyc2
SRR25158351_k127_305288_40	1313172.YM304_02800	1.472e-66	233.0	COG1978@1|root,COG1978@2|Bacteria,2GQU6@201174|Actinobacteria	201174|Actinobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRR25158351_k127_305288_56	1313172.YM304_02800	5.987e-36	141.0	COG1978@1|root,COG1978@2|Bacteria,2GQU6@201174|Actinobacteria	201174|Actinobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRR25158351_k127_305288_46	318161.Sden_1479	7.968e-56	202.0	COG2258@1|root,COG2258@2|Bacteria,1RE2Q@1224|Proteobacteria,1SEFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_305288_55	1205680.CAKO01000029_gene5067	4.338e-37	154.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,2U4VQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_305288_11	305900.GV64_17925	1.172e-138	460.0	COG1520@1|root,COG1520@2|Bacteria,1R8EB@1224|Proteobacteria,1SN3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_305288_42	1123320.KB889697_gene8992	3.647e-61	214.0	COG0748@1|root,COG0748@2|Bacteria,2IM1N@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_305288_36	745310.G432_18360	5.064e-73	269.0	2DBBP@1|root,2Z88Z@2|Bacteria,1R3B4@1224|Proteobacteria,2VFNS@28211|Alphaproteobacteria,2KDEN@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158351_k127_305288_1	66875.JODY01000006_gene2209	3.596e-191	607.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158351_k127_305288_66	596328.HMPREF0578_2008	8.142e-09	63.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,4D62M@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
SRR25158351_k127_305288_0	1179773.BN6_30480	1.618e-214	676.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4DYSV@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_305288_37	526227.Mesil_2804	3.652e-70	252.0	COG0834@1|root,COG0834@2|Bacteria,1WMI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158351_k127_305288_33	1121380.JNIW01000075_gene720	7.091e-76	267.0	COG0765@1|root,COG0765@2|Bacteria,1WMC9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158351_k127_305288_19	526227.Mesil_2806	1.577e-97	324.0	COG1126@1|root,COG1126@2|Bacteria,1WI0Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type polar amino acid transport system ATPase component	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158351_k127_305288_17	35754.JNYJ01000036_gene3605	3.514e-102	350.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,4DB1Y@85008|Micromonosporales	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158351_k127_305288_7	28444.JODQ01000013_gene2937	3.065e-163	542.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EJI6@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158351_k127_305288_68	1054860.KB913030_gene2619	2.168e-05	55.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria	201174|Actinobacteria	K	domain protein	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158351_k127_305288_3	1121877.JQKF01000021_gene2202	1.431e-180	587.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158351_k127_305288_18	1449063.JMLS01000001_gene4304	5.379e-101	352.0	COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli,26RTR@186822|Paenibacillaceae	91061|Bacilli	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_305288_52	1385521.N803_14430	2.896e-49	186.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4FFDQ@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158351_k127_305288_31	463191.SSEG_02503	2.281e-78	272.0	COG0693@1|root,COG0693@2|Bacteria,2H6FV@201174|Actinobacteria	201174|Actinobacteria	S	ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158351_k127_305288_38	1183438.GKIL_1672	6.265e-68	239.0	COG2343@1|root,COG2343@2|Bacteria,1G50P@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_305288_29	1077974.GOEFS_044_00250	2.584e-80	290.0	COG2141@1|root,COG2141@2|Bacteria,2H62W@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_305288_28	1157637.KB892090_gene6569	7.8e-81	291.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158351_k127_305288_16	1121017.AUFG01000038_gene804	7.099e-103	341.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4FF61@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_305288_6	656024.FsymDg_2233	3.142e-165	551.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4EXBT@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_305288_26	1380356.JNIK01000017_gene2937	8.18e-84	295.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_305288_30	1449346.JQMO01000002_gene1169	2.636e-79	273.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,2M1YU@2063|Kitasatospora	201174|Actinobacteria	S	Wyosine base formation	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
SRR25158351_k127_305288_2	402881.Plav_0848	1.276e-187	600.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	MA20_06755	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_305288_25	1313172.YM304_19260	1.446e-86	298.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_305288_22	1463825.JNXC01000015_gene7555	4.151e-92	323.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4DYX1@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_305288_43	1283283.ATXA01000004_gene4380	4.155e-59	213.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4ESMK@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
SRR25158351_k127_305288_13	1229780.BN381_10277	1.647e-125	409.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,3UXGG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158351_k127_305288_5	561175.KB894101_gene4520	1.809e-165	541.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EIFF@85012|Streptosporangiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_305288_8	749927.AMED_0115	4.314e-157	502.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4E032@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158351_k127_305288_54	1313172.YM304_20220	3.233e-45	175.0	2DMMI@1|root,32SFN@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
SRR25158351_k127_305288_48	1224163.B841_04820	2.262e-54	203.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,22MCA@1653|Corynebacteriaceae	201174|Actinobacteria	G	COG0406 Fructose-2,6-bisphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158351_k127_305288_64	1449069.JMLO01000019_gene2787	6.914e-12	69.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4FXYN@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158351_k127_315050_1	471852.Tcur_3525	3.679e-105	348.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EP1W@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_315050_3	1169154.KB897777_gene3670	2.298e-59	225.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	JD73_05665	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158351_k127_315050_0	525909.Afer_0085	1.111e-129	426.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_315050_2	1463856.JOHY01000001_gene428	2.511e-99	348.0	COG2025@1|root,COG2086@1|root,COG2025@2|Bacteria,COG2086@2|Bacteria,2IIH6@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
SRR25158351_k127_315050_4	1121933.AUHH01000006_gene699	2.34e-40	155.0	COG2259@1|root,COG2259@2|Bacteria,2IJ0I@201174|Actinobacteria,4DRJ9@85009|Propionibacteriales	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158351_k127_317439_12	243090.RB9620	2.294e-12	75.0	2DECI@1|root,32U34@2|Bacteria,2J46S@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158351_k127_317439_5	489825.LYNGBM3L_09750	1.325e-53	196.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158351_k127_317439_6	1340493.JNIF01000003_gene4740	2.147e-47	190.0	COG1216@1|root,COG1216@2|Bacteria,3Y7UY@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_317439_2	298655.KI912267_gene6855	1.055e-77	270.0	COG1028@1|root,COG1028@2|Bacteria,2GKT2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_317439_7	1379270.AUXF01000002_gene1293	6.64e-42	159.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158351_k127_317439_8	1125863.JAFN01000001_gene2333	8.18e-26	108.0	COG2161@1|root,COG2161@2|Bacteria,1R2Q0@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158351_k127_317439_1	1448389.BAVQ01000002_gene2863	2.102e-84	284.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_317439_10	1380390.JIAT01000009_gene612	8.817e-17	84.0	COG5660@1|root,COG5660@2|Bacteria,2HRSR@201174|Actinobacteria,4CTVV@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158351_k127_317439_3	1110697.NCAST_05_00890	1.537e-63	229.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4FXCZ@85025|Nocardiaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_317439_0	1121935.AQXX01000089_gene4656	6.337e-133	426.0	COG0655@1|root,COG0655@2|Bacteria,1N5Q7@1224|Proteobacteria,1RY1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158351_k127_317439_11	526225.Gobs_3865	3.341e-15	83.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158351_k127_317439_9	66429.JOFL01000011_gene2496	2.759e-18	98.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158351_k127_348132_8	1278078.G419_00060	7.205e-106	356.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria,4FYBI@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE27	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_348132_3	1229780.BN381_400017	3.938e-164	529.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_348132_12	247634.GPB2148_2967	5.59e-79	272.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,1RY4N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	xdh	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_348132_10	1048339.KB913029_gene1045	5.981e-84	297.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EV45@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_348132_5	101510.RHA1_ro02355	4.242e-136	445.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4FYCE@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_348132_16	1283283.ATXA01000003_gene1502	2.93e-56	216.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,4EVB5@85013|Frankiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_348132_13	101510.RHA1_ro04587	1.844e-71	252.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4FZKA@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_348132_21	1041522.MCOL_V220351	5.822e-20	94.0	COG0599@1|root,COG0599@2|Bacteria,2HCR9@201174|Actinobacteria,232H7@1762|Mycobacteriaceae	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158351_k127_348132_11	426716.JOAJ01000001_gene1104	5.8e-80	279.0	COG2141@1|root,COG2141@2|Bacteria,2HVKH@201174|Actinobacteria,4FVX1@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_348132_4	1429046.RR21198_1085	3.763e-144	484.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria,4FVNW@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE26	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_348132_9	1265310.CCBD010000014_gene3774	8.513e-101	357.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria,238IV@1762|Mycobacteriaceae	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	kce_2	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158351_k127_348132_14	164757.Mjls_2549	4.122e-68	243.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,234E2@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
SRR25158351_k127_348132_19	164757.Mjls_0315	5.169e-50	189.0	COG1028@1|root,COG1028@2|Bacteria,2GM6W@201174|Actinobacteria,232H9@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	NAD-dependent epimerase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_348132_1	557599.MKAN_03230	1.546e-205	655.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,23CXI@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
SRR25158351_k127_348132_17	1123320.KB889700_gene9200	1.245e-55	199.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_348132_15	1278073.MYSTI_04826	3.522e-61	220.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_348132_18	1394178.AWOO02000024_gene5605	1.226e-53	199.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_348132_6	479433.Caci_8748	9.484e-123	400.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158351_k127_348132_20	1236902.ANAS01000031_gene2861	1.674e-41	163.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4EK42@85012|Streptosporangiales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_348132_7	1219035.NT2_06_02540	1.038e-113	379.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1062 Zn-dependent alcohol dehydrogenases, class III	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_348132_2	298655.KI912266_gene5536	1.819e-182	584.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA_1	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_348132_0	749414.SBI_06328	1.978e-238	754.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
SRR25158351_k127_370748_6	713586.KB900536_gene2793	1.455e-74	276.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,1T2IX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_370748_13	1120797.KB908268_gene3392	1.092e-27	127.0	COG3057@1|root,COG3057@2|Bacteria,2IJT9@201174|Actinobacteria,239JM@1762|Mycobacteriaceae	201174|Actinobacteria	L	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_370748_10	234621.RER_09350	4.408e-44	172.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4FUTM@85025|Nocardiaceae	201174|Actinobacteria	I	enoyl-CoA hydratase	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_370748_11	1121017.AUFG01000033_gene296	2.714e-32	134.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4FH7U@85021|Intrasporangiaceae	201174|Actinobacteria	I	COG2030 Acyl dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_370748_8	1122247.C731_3683	4.069e-53	192.0	COG3631@1|root,COG3631@2|Bacteria,2IJ87@201174|Actinobacteria,2397V@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_370748_2	1089544.KB912942_gene4161	3.678e-111	392.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_370748_1	1160137.KB907307_gene1637	3.923e-132	437.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_370748_15	381666.H16_B2485	1.045e-12	74.0	COG1917@1|root,COG1917@2|Bacteria,1N73J@1224|Proteobacteria,2W3MW@28216|Betaproteobacteria,1KAZZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_370748_9	1123279.ATUS01000001_gene2759	9.02e-45	174.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,1T3IK@1236|Gammaproteobacteria,1JAB3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_370748_7	1160137.KB907307_gene656	1.061e-58	216.0	COG1028@1|root,COG1028@2|Bacteria,2HFNN@201174|Actinobacteria,4FUCT@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_370748_3	875328.JDM601_1115	1.893e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,236RZ@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_370748_4	365528.KB891192_gene3578	8.13e-90	303.0	COG0410@1|root,COG0410@2|Bacteria,2IH68@201174|Actinobacteria	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158351_k127_370748_0	365528.KB891192_gene3577	0.0	1102.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU9I@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158351_k127_370748_5	222534.KB893672_gene2978	1.694e-78	278.0	COG0683@1|root,COG0683@2|Bacteria,2IB96@201174|Actinobacteria	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_370748_12	298655.KI912266_gene3863	9.727e-31	130.0	COG5517@1|root,COG5517@2|Bacteria,2IG3J@201174|Actinobacteria,4EW9V@85013|Frankiales	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_370748_14	1209984.BN978_04195	5.289e-18	86.0	COG1960@1|root,COG1960@2|Bacteria,2GP53@201174|Actinobacteria,234QY@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_40090_2	1227487.C474_09849	2.622e-91	314.0	COG0665@1|root,arCOG00755@2157|Archaea,2XSYW@28890|Euryarchaeota,23SB4@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158351_k127_40090_0	298654.FraEuI1c_2471	9.241e-202	635.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_40090_4	234621.RER_33740	4.18e-75	268.0	28KAT@1|root,2Z9XX@2|Bacteria,2GNVW@201174|Actinobacteria,4FUSP@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_40090_5	996637.SGM_6077	5.276e-71	249.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158351_k127_40090_10	44454.NF84_10090	5.65e-22	102.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,23579@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158351_k127_40090_12	1449048.JQKU01000013_gene3269	4.459e-09	70.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,23632@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Wax ester synthase-like Acyl-CoA acyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158351_k127_40090_1	330084.JNYZ01000038_gene4168	2.707e-141	465.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRR25158351_k127_40090_7	1440774.Y900_001520	9.233e-43	160.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,238VI@1762|Mycobacteriaceae	201174|Actinobacteria	S	deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_40090_6	1313172.YM304_09550	1.319e-45	185.0	COG1309@1|root,COG1309@2|Bacteria,2HGBF@201174|Actinobacteria,4CNA8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_40090_3	266117.Rxyl_0748	5.152e-84	289.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_40090_8	1517681.HW45_13430	1.252e-27	125.0	COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158351_k127_40090_9	351607.Acel_0544	8.322e-25	114.0	2C0MY@1|root,2ZC2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_40090_11	1150474.JQJI01000002_gene1216	1.52e-17	92.0	COG2206@1|root,COG2206@2|Bacteria,2GCY6@200918|Thermotogae	200918|Thermotogae	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158351_k127_408843_16	928724.SacglDRAFT_04095	1.046e-35	139.0	COG0304@1|root,COG0304@2|Bacteria,2IAET@201174|Actinobacteria,4E090@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_408843_7	1408433.JHXV01000002_gene442	1.587e-90	317.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
SRR25158351_k127_408843_9	404589.Anae109_3179	8.107e-88	315.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
SRR25158351_k127_408843_25	1121033.AUCF01000020_gene644	1.019e-14	86.0	COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQTN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158351_k127_408843_0	1907.SGLAU_31485	2.685e-183	607.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_408843_17	591158.SSMG_07949	1.317e-30	134.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	plsC1	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158351_k127_408843_2	909613.UO65_3371	5.549e-110	369.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_408843_22	1229780.BN381_130311	5.008e-18	85.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158351_k127_408843_24	35754.JNYJ01000058_gene8608	3.329e-15	89.0	COG0681@1|root,COG5002@1|root,COG0681@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7,PAS_9,Response_reg
SRR25158351_k127_408843_14	857087.Metme_3172	9.918e-45	178.0	COG2905@1|root,COG3176@1|root,COG2905@2|Bacteria,COG3176@2|Bacteria,1MZ91@1224|Proteobacteria	2|Bacteria	T	Acetyltransferase (GNAT) domain	-	-	-	ko:K07003,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Acetyltransf_5,Aminotran_5,CBS,Lipase_GDSL_2,NTP_transferase,cNMP_binding
SRR25158351_k127_408843_19	298655.KI912267_gene6941	4.784e-29	130.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SRR25158351_k127_408843_8	1133849.O3I_002925	2.251e-89	301.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4FUTM@85025|Nocardiaceae	201174|Actinobacteria	I	enoyl-CoA hydratase	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_408843_11	1313172.YM304_07200	2.048e-78	274.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria	201174|Actinobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158351_k127_408843_6	101510.RHA1_ro03188	3.175e-104	365.0	COG0515@1|root,COG0515@2|Bacteria,2GKFY@201174|Actinobacteria,4FZ9V@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pkn5	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158351_k127_408843_18	208439.AJAP_15560	1.656e-30	131.0	2AYTJ@1|root,31QYX@2|Bacteria,2IA8K@201174|Actinobacteria,4DYA3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_408843_15	1229780.BN381_290040	2.051e-42	164.0	COG3669@1|root,COG3669@2|Bacteria,2HUEI@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
SRR25158351_k127_408843_3	1236902.ANAS01000001_gene1855	5.715e-110	385.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_408843_4	365528.KB891103_gene3844	1.881e-108	356.0	COG0778@1|root,COG0778@2|Bacteria,2I94X@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_408843_1	1313172.YM304_15410	2.947e-164	529.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_408843_12	1229780.BN381_40064	8.665e-70	250.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158351_k127_408843_21	368407.Memar_2494	4.471e-18	98.0	arCOG05253@1|root,arCOG05253@2157|Archaea,2Y4YF@28890|Euryarchaeota,2NB34@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_408843_10	368407.Memar_1826	8.396e-79	284.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,2N9VR@224756|Methanomicrobia	224756|Methanomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158351_k127_408843_20	749414.SBI_02630	1.07e-20	103.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_408843_26	419947.MRA_3676	1.749e-06	55.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,234FU@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase, mutator	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR25158351_k127_408843_5	1122182.KB903813_gene2279	1.212e-104	372.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DBPZ@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158351_k127_408843_27	1278073.MYSTI_01991	5.769e-06	48.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUBG@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_408843_23	1206101.AZXC01000027_gene5577	1.038e-17	97.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_408843_13	1121015.N789_14725	5.491e-56	224.0	COG1470@1|root,COG1470@2|Bacteria,1R1M6@1224|Proteobacteria	1224|Proteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_411325_6	555793.WSK_3610	4.329e-33	134.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,2K4UJ@204457|Sphingomonadales	204457|Sphingomonadales	C	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_411325_4	1394178.AWOO02000066_gene156	2.693e-100	341.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
SRR25158351_k127_411325_3	1121904.ARBP01000021_gene3593	5.216e-189	611.0	COG3794@1|root,COG3794@2|Bacteria,4NG61@976|Bacteroidetes,47MGM@768503|Cytophagia	976|Bacteroidetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_411325_5	298653.Franean1_3151	1.117e-56	214.0	COG0683@1|root,COG0683@2|Bacteria,2HZXR@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_411325_2	365528.KB891221_gene734	3.647e-295	923.0	COG0410@1|root,COG0477@1|root,COG0410@2|Bacteria,COG0477@2|Bacteria,2IFX5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,MFS_1
SRR25158351_k127_411325_0	365528.KB891221_gene735	0.0	1117.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EUV2@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158351_k127_411325_1	235985.BBPN01000009_gene3843	9.282e-302	940.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,2NJXT@228398|Streptacidiphilus	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_446967_36	1112204.GPOL_c11390	4.729e-41	163.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria,4GFXK@85026|Gordoniaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRR25158351_k127_446967_42	2045.KR76_10150	4.09e-32	142.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	pslJ	-	-	ko:K02847,ko:K21003	ko00540,ko01100,ko02025,map00540,map01100,map02025	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
SRR25158351_k127_446967_14	479434.Sthe_1662	1.4e-109	365.0	COG0473@1|root,COG0473@2|Bacteria,2GAQN@200795|Chloroflexi,27XMV@189775|Thermomicrobia	189775|Thermomicrobia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41,1.1.1.42	ko:K00030,ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R00709,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_446967_35	1123024.AUII01000008_gene1902	1.625e-47	189.0	COG0189@1|root,COG0189@2|Bacteria,2HSCJ@201174|Actinobacteria,4ED9G@85010|Pseudonocardiales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_446967_22	1123024.AUII01000008_gene1901	3.221e-70	255.0	COG3919@1|root,COG3919@2|Bacteria	2|Bacteria	E	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Polysacc_deac_1
SRR25158351_k127_446967_19	768671.ThimaDRAFT_3205	2.36e-79	276.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158351_k127_446967_44	2045.KR76_10205	9.255e-28	128.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158351_k127_446967_54	1278073.MYSTI_04708	1.998e-05	58.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,42VU5@68525|delta/epsilon subdivisions,2WSGU@28221|Deltaproteobacteria,2YX5B@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158351_k127_446967_52	477641.MODMU_4700	6.001e-08	66.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158351_k127_446967_43	1907.SGLAU_12335	8.576e-28	123.0	COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158351_k127_446967_48	670307.HYPDE_29583	5.431e-18	98.0	COG1216@1|root,COG1216@2|Bacteria,1NK8J@1224|Proteobacteria,2UKYQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_446967_40	1192759.AKIB01000088_gene2349	1.913e-36	159.0	COG5653@1|root,COG5653@2|Bacteria,1N3Z9@1224|Proteobacteria,2TRT5@28211|Alphaproteobacteria,2K1RW@204457|Sphingomonadales	204457|Sphingomonadales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158351_k127_446967_29	1312954.KI914852_gene547	5.784e-55	212.0	COG3919@1|root,COG3919@2|Bacteria,2IENT@201174|Actinobacteria	201174|Actinobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_446967_32	1122939.ATUD01000010_gene2955	4.249e-49	186.0	COG2850@1|root,COG2850@2|Bacteria,2HR84@201174|Actinobacteria,4CT47@84995|Rubrobacteria	84995|Rubrobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158351_k127_446967_4	644966.Tmar_0757	5.626e-167	542.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158351_k127_446967_12	1313172.YM304_10560	1.523e-110	371.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CMRB@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase family 4	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158351_k127_446967_28	1121877.JQKF01000003_gene1526	1.709e-57	214.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CN12@84992|Acidimicrobiia	84992|Acidimicrobiia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158351_k127_446967_47	1121365.AQXB01000005_gene1739	3.052e-21	98.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,22NUS@1653|Corynebacteriaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158351_k127_446967_50	404589.Anae109_4485	2.327e-12	78.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158351_k127_446967_33	1313172.YM304_10630	2.802e-48	183.0	COG0712@1|root,COG0712@2|Bacteria,2HGFG@201174|Actinobacteria,4CND3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158351_k127_446967_0	1313172.YM304_10640	2.999e-247	775.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CMTI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158351_k127_446967_10	1313172.YM304_10650	1.41e-113	374.0	COG0224@1|root,COG3743@1|root,COG0224@2|Bacteria,COG3743@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CN1H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158351_k127_446967_2	269800.Tfu_2407	1.582e-209	662.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4EG3U@85012|Streptosporangiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158351_k127_446967_45	1313172.YM304_10670	5.395e-24	114.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1609	ATP-synt_DE,ATP-synt_DE_N
SRR25158351_k127_446967_25	1380356.JNIK01000015_gene2514	9.085e-65	233.0	COG3103@1|root,COG5479@1|root,COG4991@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4EX5K@85013|Frankiales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SRR25158351_k127_446967_31	118161.KB235922_gene3794	1.381e-52	198.0	COG0457@1|root,COG0457@2|Bacteria,1GQBQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRR25158351_k127_446967_8	44060.JODL01000002_gene2385	3.572e-124	420.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria	201174|Actinobacteria	G	Fructose-1,6-bisphosphatase	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158351_k127_446967_27	2055.JNXA01000005_gene330	3.818e-60	218.0	COG1028@1|root,COG1028@2|Bacteria,2GMJU@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_446967_26	1313172.YM304_29040	2.258e-64	240.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4CNC2@84992|Acidimicrobiia	84992|Acidimicrobiia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_446967_39	33898.JRHJ01000078_gene943	1.607e-37	159.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	acoC	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158351_k127_446967_46	1219035.NT2_04_00110	6.576e-23	114.0	COG4308@1|root,COG4308@2|Bacteria,1RJ3T@1224|Proteobacteria,2UAH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Limonene-1,2-epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LEH
SRR25158351_k127_446967_55	1313172.YM304_16690	4.455e-05	53.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CMUP@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158351_k127_446967_18	110319.CF8_2241	1.219e-79	283.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria,4DQ9V@85009|Propionibacteriales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158351_k127_446967_56	262316.MAP_0029c	0.0001067	55.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_446967_9	1123320.KB889689_gene518	1.023e-121	402.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
SRR25158351_k127_446967_17	1089546.AQUI01000002_gene2030	1.688e-80	278.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,40811@622450|Actinopolysporales	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_446967_5	1172180.KB911795_gene7772	2.033e-144	469.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_446967_11	1313172.YM304_10710	9.869e-111	383.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2HF92@201174|Actinobacteria,4CNT6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158351_k127_446967_41	471853.Bcav_3866	9.844e-35	142.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158351_k127_446967_37	1380390.JIAT01000009_gene927	7.075e-40	156.0	COG2114@1|root,COG2114@2|Bacteria,2ICJJ@201174|Actinobacteria,4CQDR@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158351_k127_446967_34	1370121.AUWS01000097_gene3461	4.467e-48	186.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,234BT@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,5.3.3.18	ko:K01692,ko:K15866	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R09837,R09839	RC00004,RC00326,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_446967_7	1283283.ATXA01000002_gene2447	3.767e-126	418.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4ERJ6@85013|Frankiales	201174|Actinobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158351_k127_446967_49	880073.Calab_0458	2.596e-17	89.0	COG0694@1|root,COG0694@2|Bacteria,2NQ7X@2323|unclassified Bacteria	2|Bacteria	O	NifU-like domain	nifU	-	-	-	-	-	-	-	-	-	-	-	NifU
SRR25158351_k127_446967_13	1313172.YM304_10780	4.464e-110	365.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CMYQ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158351_k127_446967_21	2074.JNYD01000008_gene1143	4.996e-73	255.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4DXUE@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_446967_30	264732.Moth_1935	3.539e-54	203.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,42F43@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Galactose-1-phosphate uridyl transferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
SRR25158351_k127_446967_3	1313172.YM304_28810	3.317e-184	586.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CMT7@84992|Acidimicrobiia	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_446967_24	1382356.JQMP01000001_gene1220	3.736e-67	240.0	COG0384@1|root,COG0384@2|Bacteria,2G7U6@200795|Chloroflexi,27ZAQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158351_k127_446967_1	1229780.BN381_10171	8.872e-229	723.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,3UWDD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158351_k127_446967_38	309807.SRU_0529	1.486e-39	160.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1FJI1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Biotin protein ligase C terminal domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
SRR25158351_k127_446967_16	1352941.M877_34360	1.553e-87	298.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_446967_20	67267.JNXT01000022_gene1291	5.793e-78	277.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria	201174|Actinobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158351_k127_446967_23	1229780.BN381_310079	1.517e-67	250.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,3UXS8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158351_k127_446967_6	909613.UO65_6177	1.497e-135	446.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4DXCQ@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158351_k127_446967_15	235985.BBPN01000001_gene1048	4.826e-94	332.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,2NKS3@228398|Streptacidiphilus	201174|Actinobacteria	GM	RmlD substrate binding domain	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158351_k127_457805_11	262316.MAP_1975	3.59e-11	68.0	2DZ2P@1|root,34C7Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_457805_5	1121377.KB906402_gene3167	6.903e-34	148.0	COG0429@1|root,COG0429@2|Bacteria	2|Bacteria	S	poly(3-hydroxybutyrate) depolymerase activity	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,NPCBM
SRR25158351_k127_457805_9	1151119.KB895502_gene3030	1.03e-17	97.0	COG3291@1|root,COG5479@1|root,COG3291@2|Bacteria,COG5479@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CBM_4_9,LGFP
SRR25158351_k127_457805_3	1380356.JNIK01000013_gene4196	4.394e-39	158.0	2AZDP@1|root,31RMA@2|Bacteria,2GUFH@201174|Actinobacteria,4EW1B@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRR25158351_k127_457805_12	298653.Franean1_6925	1.078e-10	75.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_457805_8	710686.Mycsm_03934	5.275e-26	115.0	COG0454@1|root,COG0456@2|Bacteria,2I582@201174|Actinobacteria,23A4U@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_457805_0	909613.UO65_4966	4.639e-127	424.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4E2AT@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA,TspO_MBR
SRR25158351_k127_457805_1	1121363.KB902193_gene2554	4.646e-102	344.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,22KHS@1653|Corynebacteriaceae	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
SRR25158351_k127_457805_4	1123024.AUII01000028_gene2518	4.233e-36	151.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158351_k127_457805_13	351160.RCIX1452	9.356e-09	63.0	arCOG03391@1|root,arCOG03391@2157|Archaea,2Y097@28890|Euryarchaeota,2N9ZQ@224756|Methanomicrobia	224756|Methanomicrobia	S	membrane-bound metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
SRR25158351_k127_457805_7	1123024.AUII01000006_gene4623	6.982e-29	126.0	COG0328@1|root,COG0328@2|Bacteria,2I4IN@201174|Actinobacteria,4EEAK@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase-like	-	-	3.1.26.4,3.1.3.73	ko:K03469,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Glyoxalase_4,His_Phos_1,RVT_3
SRR25158351_k127_457805_6	1120936.KB907211_gene211	5.923e-33	138.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4EH3Z@85012|Streptosporangiales	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158351_k127_457805_2	1121430.JMLG01000012_gene1976	1.914e-85	308.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,260M6@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158351_k127_457805_10	1313172.YM304_18810	1.593e-12	74.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158351_k127_458446_14	1123023.JIAI01000003_gene2845	7.222e-39	150.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4DZ01@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_458446_0	645465.ACUR01000575_gene1381	5.494e-184	599.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2I931@201174|Actinobacteria	201174|Actinobacteria	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRR25158351_k127_458446_3	767029.HMPREF9154_0719	1.784e-110	368.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DN4V@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158351_k127_458446_12	1227349.C170_15325	1.315e-60	233.0	COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,4HC0D@91061|Bacilli,26RRD@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport systems, permease components	ugpA1	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
SRR25158351_k127_458446_9	1157490.EL26_16825	3.787e-77	267.0	COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,4HB8C@91061|Bacilli,27APG@186823|Alicyclobacillaceae	91061|Bacilli	U	Binding-protein-dependent transport system inner membrane component	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
SRR25158351_k127_458446_8	292459.STH2179	1.927e-80	286.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
SRR25158351_k127_458446_10	935845.JADQ01000021_gene4130	2.612e-66	248.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HARC@91061|Bacilli,274JR@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system, periplasmic component	upgB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
SRR25158351_k127_458446_6	1380390.JIAT01000012_gene2922	2.369e-101	351.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4CT0K@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_458446_16	1313172.YM304_28130	2.262e-18	99.0	COG1545@1|root,COG1545@2|Bacteria,2IFHZ@201174|Actinobacteria	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_458446_5	257310.BB1083	3.088e-104	361.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2W1IE@28216|Betaproteobacteria,3T1DH@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_458446_13	1437882.AZRU01000020_gene6115	9.745e-55	210.0	COG1024@1|root,COG1024@2|Bacteria,1PHX3@1224|Proteobacteria,1TBMY@1236|Gammaproteobacteria,1YI4S@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_458446_4	13690.CP98_00468	2.345e-110	370.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2K1N3@204457|Sphingomonadales	204457|Sphingomonadales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_458446_1	1120934.KB894410_gene6966	5.578e-184	595.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4DYQ2@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158351_k127_458446_11	298655.KI912266_gene2716	1.499e-65	237.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_458446_15	931627.MycrhDRAFT_1216	4.758e-22	102.0	COG2030@1|root,COG2030@2|Bacteria,2IKE4@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158351_k127_458446_7	1380390.JIAT01000012_gene2956	1.254e-88	311.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4CRE1@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04116	ko00362,ko01120,map00362,map01120	M00540	R05620	RC00004,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_458446_2	298654.FraEuI1c_2890	2.093e-158	509.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4ERYE@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_462312_0	469371.Tbis_0886	6.225e-145	494.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DX4E@85010|Pseudonocardiales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158351_k127_462312_1	1229780.BN381_10014	1.799e-129	439.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158351_k127_462312_2	479432.Sros_6513	1.265e-88	317.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4EQ0V@85012|Streptosporangiales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
SRR25158351_k127_462312_3	67315.JOBD01000015_gene6580	1.049e-83	301.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
SRR25158351_k127_477059_13	656024.FsymDg_3963	1.704e-15	76.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158351_k127_477059_12	525909.Afer_0383	2.048e-19	88.0	COG0267@1|root,COG0267@2|Bacteria,2HH2Z@201174|Actinobacteria,4CP34@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158351_k127_477059_10	1229780.BN381_610018	1.079e-40	158.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_477059_15	1229780.BN381_350057	1.678e-09	63.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158351_k127_477059_5	1229780.BN381_350058	7.957e-68	246.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,3UWJ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158351_k127_477059_7	1122138.AQUZ01000015_gene6801	2.99e-56	202.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4DQC0@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158351_k127_477059_3	525909.Afer_0388	7.806e-95	322.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CMU4@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158351_k127_477059_8	1313172.YM304_07930	3.507e-46	181.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CN6B@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158351_k127_477059_9	298655.KI912266_gene338	8.068e-45	178.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4ESPE@85013|Frankiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158351_k127_477059_1	1232429.CBLL010000049_gene1908	0.0	1371.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,1W8D1@1268|Micrococcaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158351_k127_477059_0	1048339.KB913029_gene2736	0.0	1597.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4ERS7@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158351_k127_477059_6	446471.Xcel_0622	1.92e-59	220.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4F4H7@85017|Promicromonosporaceae	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158351_k127_477059_4	1229780.BN381_180002	6.197e-73	248.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,3UWK1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158351_k127_477059_2	1121877.JQKF01000009_gene551	0.0	1037.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CMTM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_477059_14	953739.SVEN_4374	1.698e-12	80.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158351_k127_479066_14	1229780.BN381_450016	1.035e-106	351.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,3UX9K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	menJ	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158351_k127_479066_37	1132441.KI519455_gene3048	0.0003332	53.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_479066_26	525909.Afer_0363	8.204e-36	141.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CN51@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158351_k127_479066_17	1229780.BN381_450005	2.882e-84	283.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,3UWJQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158351_k127_479066_30	1313172.YM304_04080	5.361e-33	142.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CN4G@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158351_k127_479066_7	525909.Afer_0366	3.609e-177	573.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CMP9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158351_k127_479066_29	222534.KB893739_gene1385	1.577e-33	147.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4ESCP@85013|Frankiales	201174|Actinobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158351_k127_479066_11	765869.BDW_11310	8.367e-125	421.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2MTQY@213481|Bdellovibrionales,2WJ1W@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158351_k127_479066_3	1229780.BN381_160007	1.33e-220	717.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,3UWBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158351_k127_479066_10	1121877.JQKF01000009_gene576	8.384e-129	426.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CMTV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158351_k127_479066_15	1229780.BN381_160009	1.222e-98	327.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,3UWSS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR25158351_k127_479066_31	1121877.JQKF01000009_gene574	8.072e-33	136.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4CN8Y@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158351_k127_479066_33	525909.Afer_0373	3.103e-29	119.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CN4N@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158351_k127_479066_5	1229780.BN381_160012	1.234e-187	608.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,3UWAP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158351_k127_479066_9	1313172.YM304_04180	9.155e-143	479.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CMUB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein synonym NADH dehydrogenase I subunit M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_479066_12	1229780.BN381_160014	1.621e-115	392.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,3UWFY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_479066_1	243230.DR_1742	3.228e-235	738.0	COG0166@1|root,COG0166@2|Bacteria,1WIGN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158351_k127_479066_24	1229780.BN381_50095	1.187e-43	175.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158351_k127_479066_18	1229780.BN381_160024	6.322e-83	295.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,3UWJQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158351_k127_479066_23	1313172.YM304_35630	1.006e-46	178.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158351_k127_479066_6	1313172.YM304_35620	1.555e-179	577.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CMP9@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158351_k127_479066_13	1229780.BN381_160027	8.01e-109	362.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,3UW85@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158351_k127_479066_19	1313172.YM304_35600	3.818e-75	258.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158351_k127_479066_25	1157635.KB892002_gene4309	4.879e-36	147.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158351_k127_479066_32	1229780.BN381_160031	2.217e-32	128.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158351_k127_479066_2	1229780.BN381_160032	2.628e-228	726.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,3UWAP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158351_k127_479066_4	1229780.BN381_160033	2.175e-215	680.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,3UWBE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_479066_8	1313172.YM304_35550	4.985e-154	505.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CMT6@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_479066_20	1313172.YM304_35500	8.417e-66	242.0	COG1565@1|root,COG1565@2|Bacteria	2|Bacteria	P	acr, cog1565	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158351_k127_479066_27	1120949.KB903294_gene4030	2.534e-35	141.0	COG3247@1|root,COG3247@2|Bacteria,2ISIY@201174|Actinobacteria,4DMAA@85008|Micromonosporales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158351_k127_479066_0	1313172.YM304_35460	1.437e-307	956.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158351_k127_479066_35	455632.SGR_702	3.353e-14	83.0	COG5083@1|root,COG5083@2|Bacteria,2IFC7@201174|Actinobacteria,41CEV@629295|Streptomyces griseus group	201174|Actinobacteria	S	phosphatidylinositol transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158351_k127_479066_28	1215092.PA6_018_00110	1.059e-34	143.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,1RYTA@1236|Gammaproteobacteria,1YGFJ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_479066_16	1229780.BN381_190008	2.496e-84	297.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,3UWMI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Peptidase family M48	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_479066_22	1313172.YM304_35430	3.623e-48	178.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4CN1Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158351_k127_479066_21	1229780.BN381_190004	2.289e-58	207.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,3UXM9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158351_k127_479066_34	1458462.JNLK01000001_gene129	1.822e-15	79.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,27I75@186928|unclassified Lachnospiraceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158351_k127_493856_5	1380356.JNIK01000002_gene4844	5.352e-103	352.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	ylbG	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_29,rve,rve_3
SRR25158351_k127_493856_15	549.BW31_03494	5.064e-08	59.0	COG3620@1|root,COG3620@2|Bacteria,1N4KQ@1224|Proteobacteria,1S8WX@1236|Gammaproteobacteria,3W19E@53335|Pantoea	1236|Gammaproteobacteria	K	Helix-turn-helix domain	VY92_07345	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_37
SRR25158351_k127_493856_8	446462.Amir_4944	5.933e-80	280.0	COG1105@1|root,COG1105@2|Bacteria,2HJ3W@201174|Actinobacteria,4DZ7A@85010|Pseudonocardiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_493856_9	590998.Celf_3165	3.142e-72	256.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4F1RV@85016|Cellulomonadaceae	201174|Actinobacteria	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158351_k127_493856_12	196162.Noca_0283	4.227e-17	84.0	2EH65@1|root,33AY1@2|Bacteria,2I34E@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876
SRR25158351_k127_493856_16	931627.MycrhDRAFT_4888	1.345e-07	64.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,2398U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158351_k127_493856_14	446471.Xcel_3215	5.707e-11	74.0	COG0265@1|root,COG0265@2|Bacteria,2IJFX@201174|Actinobacteria,4F44A@85017|Promicromonosporaceae	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_493856_17	497965.Cyan7822_4323	3.2e-07	61.0	COG3246@1|root,COG3246@2|Bacteria,1G2CW@1117|Cyanobacteria	1117|Cyanobacteria	S	Pfam:Kce	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158351_k127_493856_10	298653.Franean1_3705	1.226e-35	144.0	COG3467@1|root,COG3467@2|Bacteria,2H5XT@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_493856_2	1117379.BABA_14322	3.121e-142	466.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_493856_1	1380390.JIAT01000013_gene51	4.635e-176	592.0	COG3899@1|root,COG3899@2|Bacteria,2HFRA@201174|Actinobacteria,4CR76@84995|Rubrobacteria	84995|Rubrobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158351_k127_493856_13	298655.KI912266_gene6084	5.725e-16	87.0	COG5401@1|root,COG5401@2|Bacteria,2H4HT@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158351_k127_493856_18	1313172.YM304_11160	1.303e-05	55.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CCP_MauG,Copper-bind,Cu-oxidase_3,Cupredoxin_1
SRR25158351_k127_493856_3	1440774.Y900_013670	2.729e-125	409.0	COG2141@1|root,COG2141@2|Bacteria,2IBDS@201174|Actinobacteria,2368G@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_493856_4	1313172.YM304_15820	1.568e-107	355.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	htdY	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158351_k127_493856_7	1223545.GS4_07_01380	2.835e-86	299.0	COG1960@1|root,COG1960@2|Bacteria,2IAYB@201174|Actinobacteria,4GDMW@85026|Gordoniaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
SRR25158351_k127_493856_20	1203190.CAJP01000034_gene1282	6.877e-05	53.0	COG3314@1|root,COG3314@2|Bacteria,2H3YE@201174|Actinobacteria,22M0D@1653|Corynebacteriaceae	201174|Actinobacteria	S	Transporter gate domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
SRR25158351_k127_493856_11	1229780.BN381_170006	7.857e-20	92.0	2CC1Y@1|root,32YV9@2|Bacteria,2HGFB@201174|Actinobacteria,3UXMX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Transcription factor WhiB	-	-	-	-	-	-	-	-	-	-	-	-	Whib
SRR25158351_k127_493856_0	1121877.JQKF01000010_gene730	2.127e-183	580.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNGH@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_493856_6	1463854.JOHT01000016_gene7048	5.256e-96	326.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158351_k127_520501_14	1283283.ATXA01000040_gene2315	0.0002224	51.0	COG4932@1|root,COG4932@2|Bacteria,2HFQY@201174|Actinobacteria,4EWQ8@85013|Frankiales	2|Bacteria	M	domain protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,Big_5,CarboxypepD_reg,DUF11,DUF3494,SdrD_B,TIG,fn3
SRR25158351_k127_520501_13	525909.Afer_0776	2.397e-06	56.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4CNAN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158351_k127_520501_6	1120936.KB907216_gene3716	5.427e-27	118.0	COG2329@1|root,COG2329@2|Bacteria,2IM1Q@201174|Actinobacteria,4EJJ8@85012|Streptosporangiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
SRR25158351_k127_520501_10	1229780.BN381_10335	1.185e-17	87.0	291CY@1|root,2ZNZT@2|Bacteria,2HDEE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_520501_4	1075090.GOAMR_20_02540	1.999e-109	366.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4GB5I@85026|Gordoniaceae	201174|Actinobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158351_k127_520501_8	235985.BBPN01000031_gene2153	2.932e-25	112.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,2NJQ5@228398|Streptacidiphilus	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158351_k127_520501_0	469383.Cwoe_4211	1.383e-271	848.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158351_k127_520501_12	1441930.Z042_22115	1.425e-06	57.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,403YD@613|Serratia	1236|Gammaproteobacteria	S	Transglycosylase associated protein	yeaQ	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158351_k127_520501_9	1313172.YM304_18490	2.923e-19	92.0	COG1278@1|root,COG1278@2|Bacteria,2HC2C@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	-
SRR25158351_k127_520501_7	471852.Tcur_3439	6.711e-26	107.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4EKE3@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158351_k127_520501_3	1313172.YM304_18510	1.402e-163	531.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CMTA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158351_k127_520501_1	1313172.YM304_18530	3.404e-214	692.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CMPC@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158351_k127_520501_11	1151126.AQYI01000005_gene2270	8.558e-11	74.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FNJ1@85023|Microbacteriaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158351_k127_520501_2	1048339.KB913029_gene3324	2.413e-194	627.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4ESA8@85013|Frankiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158351_k127_520501_5	1123065.ATWL01000011_gene12	5.246e-31	128.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria	201174|Actinobacteria	L	methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158351_k127_527375_6	526225.Gobs_2307	1.227e-67	254.0	COG1807@1|root,COG1807@2|Bacteria,2H4N7@201174|Actinobacteria,4EV7X@85013|Frankiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SRR25158351_k127_527375_1	285514.JNWO01000002_gene4881	2.971e-141	459.0	COG3173@1|root,COG3173@2|Bacteria,2GJ58@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_527375_0	222534.KB893717_gene1989	3.792e-184	587.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_527375_3	479432.Sros_8290	1.204e-132	444.0	COG0183@1|root,COG0183@2|Bacteria,2IBBS@201174|Actinobacteria,4EMWB@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158351_k127_527375_5	1341646.CBMO010000079_gene371	1.973e-97	337.0	COG1024@1|root,COG1024@2|Bacteria,2IBN1@201174|Actinobacteria,237N9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_527375_9	1122247.C731_0984	2.171e-12	74.0	2AEPZ@1|root,314K8@2|Bacteria,2IEBE@201174|Actinobacteria,236M5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_527375_2	710686.Mycsm_01043	7.067e-133	431.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_527375_7	362242.MUL_0822	1.521e-63	224.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldolase	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.1.104,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K22130	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158351_k127_527375_8	118161.KB235922_gene215	1.471e-50	200.0	COG2220@1|root,COG2220@2|Bacteria,1GRPC@1117|Cyanobacteria,3VNAG@52604|Pleurocapsales	1117|Cyanobacteria	P	Beta-lactamase superfamily domain	-	-	-	ko:K14952	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	Lactamase_B_3
SRR25158351_k127_527375_4	1144325.PMI22_00739	5.993e-130	432.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158351_k127_531167_9	1041522.MCOL_V204800	4.492e-11	69.0	2EJUC@1|root,33DJ0@2|Bacteria,2IEA8@201174|Actinobacteria,23A93@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_531167_5	1048339.KB913029_gene1211	6.736e-75	259.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4ETYD@85013|Frankiales	201174|Actinobacteria	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158351_k127_531167_0	106370.Francci3_1050	0.0	1148.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria,4EXBH@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRR25158351_k127_531167_8	933801.Ahos_0995	7.03e-26	123.0	COG0438@1|root,arCOG01403@2157|Archaea,2XQAU@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_531167_10	682795.AciX8_0537	1.093e-05	57.0	COG2845@1|root,COG2845@2|Bacteria	2|Bacteria	Q	Protein of unknown function (DUF459)	Z012_00175	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
SRR25158351_k127_531167_2	710111.FraQA3DRAFT_3281	7.184e-88	310.0	COG1807@1|root,COG1807@2|Bacteria,2IITJ@201174|Actinobacteria	201174|Actinobacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158351_k127_531167_1	1229780.BN381_310090	5.563e-118	399.0	COG1807@1|root,COG1835@1|root,COG1807@2|Bacteria,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	aftB	GO:0008150,GO:0040007	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	Acyl_transf_3,PMT_2
SRR25158351_k127_531167_6	290399.Arth_2187	4.873e-69	242.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,1W8CU@1268|Micrococcaceae	201174|Actinobacteria	S	Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158351_k127_531167_7	106370.Francci3_2651	1.148e-57	225.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158351_k127_531167_3	1048339.KB913029_gene3211	1.831e-87	305.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4ESG7@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_531167_4	1380390.JIAT01000016_gene5516	2.157e-85	291.0	COG0500@1|root,COG2226@2|Bacteria,2GJGS@201174|Actinobacteria,4CRB1@84995|Rubrobacteria	84995|Rubrobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_535788_2	1449351.RISW2_19445	1.507e-60	222.0	29IES@1|root,305BZ@2|Bacteria,1RF1J@1224|Proteobacteria,2UZ7R@28211|Alphaproteobacteria,4KNNS@93682|Roseivivax	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_535788_1	1408452.JAGZ01000001_gene3756	2.013e-82	291.0	COG0596@1|root,COG0596@2|Bacteria,2HN9N@201174|Actinobacteria,2343E@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_535788_0	1229780.BN381_360040	1.783e-110	374.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipL	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_536153_9	411902.CLOBOL_06274	6.423e-30	131.0	COG0388@1|root,COG0388@2|Bacteria,1TYM2@1239|Firmicutes,24HQT@186801|Clostridia,2241A@1506553|Lachnoclostridium	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158351_k127_536153_4	1160137.KB907307_gene2853	5.016e-102	341.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4FWDA@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA12	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_536153_8	1123320.KB889683_gene2046	1.661e-36	143.0	2EACJ@1|root,334GH@2|Bacteria,2IG8C@201174|Actinobacteria	201174|Actinobacteria	S	Limonene-12-epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LEH,SnoaL_2
SRR25158351_k127_536153_0	1440774.Y900_024550	4.677e-153	493.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,23CIZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_536153_10	1229780.BN381_630007	1.359e-11	78.0	2CK2C@1|root,2ZY21@2|Bacteria,2HE72@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_536153_1	1440053.JOEI01000024_gene1194	8.774e-127	419.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria	201174|Actinobacteria	V	MATE efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158351_k127_536153_2	1229780.BN381_630010	4.497e-108	365.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,3UXD2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158351_k127_536153_3	1229780.BN381_630011	5.938e-108	370.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,3UWTN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158351_k127_536153_5	1123023.JIAI01000011_gene8824	4.225e-64	240.0	COG1024@1|root,COG1024@2|Bacteria,2H2G7@201174|Actinobacteria,4DZ8V@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA14	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_536153_6	1313172.YM304_33450	1.046e-59	220.0	COG1670@1|root,COG1670@2|Bacteria,2HFKU@201174|Actinobacteria,4CP4F@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158351_k127_536153_7	1200352.A606_03385	2.183e-51	192.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,22KJX@1653|Corynebacteriaceae	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158351_k127_536637_4	1032480.MLP_46570	0.0003492	51.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4DRSB@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_536637_0	1229780.BN381_310045	1.468e-80	276.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,3UXA6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
SRR25158351_k127_536637_3	1122921.KB898210_gene2779	3.378e-05	55.0	29Y0M@1|root,30JTI@2|Bacteria,1V50V@1239|Firmicutes,4HHX7@91061|Bacilli,26VUK@186822|Paenibacillaceae	91061|Bacilli	S	Family of unknown function (DUF5317)	M1-582	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158351_k127_536637_2	1048339.KB913029_gene3284	4.187e-25	119.0	COG2206@1|root,COG2206@2|Bacteria,2GJB1@201174|Actinobacteria,4EUK3@85013|Frankiales	201174|Actinobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158351_k127_536637_1	351607.Acel_0546	1.146e-37	149.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4ETB2@85013|Frankiales	201174|Actinobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158351_k127_539865_1	1408254.T458_20075	3.798e-83	291.0	COG0438@1|root,COG0438@2|Bacteria,1VBXR@1239|Firmicutes	1239|Firmicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158351_k127_539865_0	1123251.ATWM01000002_gene117	9.465e-93	328.0	COG1132@1|root,COG1132@2|Bacteria,2HXAQ@201174|Actinobacteria,4FFW1@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_539865_5	1137268.AZXF01000028_gene1816	1.03e-07	64.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_539865_4	876044.IMCC3088_2103	1.492e-31	140.0	COG0457@1|root,COG0457@2|Bacteria,1Q0TG@1224|Proteobacteria,1TKB9@1236|Gammaproteobacteria,1JB5F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
SRR25158351_k127_539865_2	98439.AJLL01000010_gene1321	1.159e-82	284.0	COG1216@1|root,COG1216@2|Bacteria,1G10I@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158351_k127_539865_3	33876.JNXY01000037_gene7991	5.283e-59	215.0	COG0438@1|root,COG0438@2|Bacteria,2GM53@201174|Actinobacteria,4D8SV@85008|Micromonosporales	201174|Actinobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_540978_1	525909.Afer_1808	6.377e-103	340.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CMPQ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_540978_4	1229780.BN381_10021	8.916e-63	236.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,3UWRW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158351_k127_540978_11	1121877.JQKF01000027_gene2453	5.409e-15	81.0	2ANAN@1|root,31D8Y@2|Bacteria,2HGVW@201174|Actinobacteria,4CNX0@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_540978_8	1382356.JQMP01000001_gene1284	2.626e-29	122.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi,27ZAC@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158351_k127_540978_3	1120950.KB892768_gene5306	1.954e-74	257.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,4DWQP@85009|Propionibacteriales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_540978_0	1206730.BAGA01000179_gene2867	3.58e-117	406.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,4G9JQ@85025|Nocardiaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158351_k127_540978_12	405948.SACE_1056	8.704e-06	58.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4DZ71@85010|Pseudonocardiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158351_k127_540978_9	1035308.AQYY01000001_gene1481	2.22e-28	132.0	COG2976@1|root,COG2976@2|Bacteria,1W3FI@1239|Firmicutes,25793@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR25158351_k127_540978_2	526225.Gobs_0418	3.207e-83	296.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4EUDN@85013|Frankiales	201174|Actinobacteria	M	TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	wcaJ	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158351_k127_540978_6	1380390.JIAT01000009_gene1313	1.983e-47	186.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CBM_6,Cellulase,DUF1573,DUF4978,F5_F8_type_C,Laminin_G_3,Pectate_lyase_3,RicinB_lectin_2
SRR25158351_k127_540978_5	1380390.JIAT01000009_gene1313	8.467e-54	205.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CBM_6,Cellulase,DUF1573,DUF4978,F5_F8_type_C,Laminin_G_3,Pectate_lyase_3,RicinB_lectin_2
SRR25158351_k127_540978_10	1064537.AGSO01000006_gene1948	7.344e-26	121.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FD70@85020|Dermabacteraceae	201174|Actinobacteria	DM	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,ParA,Wzz
SRR25158351_k127_540978_7	2045.KR76_10145	1.201e-29	125.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_2_3,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158351_k127_598589_95	931627.MycrhDRAFT_5562	1.73e-10	66.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158351_k127_598589_89	1440774.Y900_006335	3.023e-13	82.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_598589_104	1123288.SOV_2c07750	3.977e-06	60.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,4H46N@909932|Negativicutes	909932|Negativicutes	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158351_k127_598589_106	1197706.AKKK01000047_gene3395	6.434e-06	55.0	COG4961@1|root,COG4961@2|Bacteria,2GWMA@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158351_k127_598589_13	525909.Afer_1347	1.632e-128	425.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CMR6@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158351_k127_598589_5	1313172.YM304_25530	4.116e-165	531.0	COG1625@1|root,COG1625@2|Bacteria,2H3RR@201174|Actinobacteria,4CMW9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
SRR25158351_k127_598589_15	1313172.YM304_25520	8.116e-126	414.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CMP7@84992|Acidimicrobiia	84992|Acidimicrobiia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158351_k127_598589_64	1229780.BN381_290068	4.417e-41	168.0	COG0204@1|root,COG0283@1|root,COG0204@2|Bacteria,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,3UWT7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158351_k127_598589_48	1229780.BN381_290068	5.919e-56	203.0	COG0204@1|root,COG0283@1|root,COG0204@2|Bacteria,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,3UWT7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158351_k127_598589_25	1125863.JAFN01000001_gene764	4.78e-98	352.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158351_k127_598589_28	1313172.YM304_24990	6.936e-86	301.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CNBS@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158351_k127_598589_78	309801.trd_0109	1.849e-22	110.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,27YKI@189775|Thermomicrobia	189775|Thermomicrobia	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158351_k127_598589_37	1229780.BN381_290070	1.771e-73	265.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,3UWKC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158351_k127_598589_45	1313172.YM304_24970	3.087e-60	223.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CN9J@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158351_k127_598589_42	1313172.YM304_24960	7.2e-65	248.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158351_k127_598589_24	1033736.CAHK01000037_gene2433	1.296e-99	352.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4F8B4@85019|Brevibacteriaceae	201174|Actinobacteria	J	tRNA synthetases class I (W and Y)	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158351_k127_598589_60	649764.HMPREF0762_00028	1.856e-46	177.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria,4CUK0@84998|Coriobacteriia	84998|Coriobacteriia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158351_k127_598589_90	1298863.AUEP01000020_gene3620	5.343e-13	73.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4DRE5@85009|Propionibacteriales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158351_k127_598589_32	1123023.JIAI01000030_gene4403	8.542e-83	290.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DYBT@85010|Pseudonocardiales	201174|Actinobacteria	L	Tyrosine recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158351_k127_598589_73	525909.Afer_1134	1.81e-29	130.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4CNBA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158351_k127_598589_2	1229780.BN381_290083	6.642e-243	771.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,3UWF5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
SRR25158351_k127_598589_110	1500893.JQNB01000001_gene2658	8.546e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,1QCMF@1224|Proteobacteria,1T8CR@1236|Gammaproteobacteria,1XAFR@135614|Xanthomonadales	135614|Xanthomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_66	469371.Tbis_2008	1.848e-36	153.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_51	1146883.BLASA_2490	9.843e-54	217.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4EURD@85013|Frankiales	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_50	1122138.AQUZ01000011_gene5013	2.045e-54	213.0	COG0728@1|root,COG0728@2|Bacteria,2II3T@201174|Actinobacteria	201174|Actinobacteria	S	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MVIN
SRR25158351_k127_598589_80	1463821.JOGR01000010_gene3866	1.567e-19	100.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4EYVC@85014|Glycomycetales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158351_k127_598589_20	28444.JODQ01000004_gene6100	2.683e-118	406.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4EHB1@85012|Streptosporangiales	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158351_k127_598589_9	1313172.YM304_24890	1.04e-141	479.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CMY1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158351_k127_598589_47	1313172.YM304_24880	1.185e-56	214.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CN3D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158351_k127_598589_39	675635.Psed_3820	4.873e-69	242.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4DY8F@85010|Pseudonocardiales	201174|Actinobacteria	J	TIGRFAM hemolysin TlyA family protein	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158351_k127_598589_55	1313172.YM304_24850	1.774e-52	197.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CN5Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158351_k127_598589_40	1048339.KB913029_gene2112	1.874e-68	265.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158351_k127_598589_8	1313172.YM304_26900	9.597e-142	469.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158351_k127_598589_1	68199.JNZO01000012_gene3388	1.062e-275	861.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158351_k127_598589_105	1313172.YM304_24830	5.684e-06	57.0	COG0629@1|root,COG0629@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_598589_65	1229780.BN381_290093	2.783e-39	161.0	COG0457@1|root,COG0457@2|Bacteria	1229780.BN381_290093|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_69	1234679.BN424_3351	3.237e-34	134.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes	1239|Firmicutes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_54	445335.CBN_0042	1.14e-52	189.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia,36VZZ@31979|Clostridiaceae	186801|Clostridia	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_77	638303.Thal_0906	1.68e-23	108.0	2DYKZ@1|root,34AAD@2|Bacteria	2|Bacteria	L	LAGLIDADG endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_1
SRR25158351_k127_598589_96	1089548.KI783301_gene3307	4.463e-10	62.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,4IRDZ@91061|Bacilli	91061|Bacilli	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_99	196164.23493383	3.675e-09	60.0	29WRJ@1|root,30ICM@2|Bacteria,2H09C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_85	253839.SSNG_03735	6.062e-16	78.0	2ED08@1|root,33H8A@2|Bacteria,2GQB6@201174|Actinobacteria	201174|Actinobacteria	S	Truncated CDS	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_92	566461.SSFG_03801	7.85e-12	66.0	2B7FZ@1|root,320JU@2|Bacteria,2IQBZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_71	566461.SSFG_07889	1.573e-31	126.0	2AHMW@1|root,317ZU@2|Bacteria,2HC22@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_98	498761.HM1_3125	3.353e-09	60.0	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_101	1121439.dsat_2904	2.672e-08	55.0	2AZ0G@1|root,31R6J@2|Bacteria,1NMSQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_75	1122971.BAME01000208_gene6774	4.885e-26	109.0	2E4EA@1|root,32Z9I@2|Bacteria,4NTWC@976|Bacteroidetes,2FU6R@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_84	1205908.AKXW01000016_gene2640	1.836e-16	79.0	2DMHR@1|root,32RMI@2|Bacteria,1QK1W@1224|Proteobacteria,1TI4F@1236|Gammaproteobacteria,1XYCQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_88	498761.HM1_3149	2.002e-14	74.0	2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,24P9Q@186801|Clostridia	186801|Clostridia	S	COG NOG14552 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_91	411467.BACCAP_03831	1.289e-12	67.0	2AEH5@1|root,314CE@2|Bacteria,1VM56@1239|Firmicutes,24XBZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_79	498761.HM1_3148	4.535e-21	93.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_107	1123313.ATUT01000005_gene249	1.336e-05	48.0	2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,3VS8M@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_76	411460.RUMTOR_02906	1.142e-24	107.0	2BRU1@1|root,32KU6@2|Bacteria,1U1G4@1239|Firmicutes,25NUE@186801|Clostridia,3Y201@572511|Blautia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_93	887929.HMP0721_2517	1.501e-11	71.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_16	700015.Corgl_1292	2.554e-125	417.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CV92@84998|Coriobacteriia	84998|Coriobacteriia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158351_k127_598589_44	1385515.N791_07615	4.201e-62	226.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria,1X6BU@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158351_k127_598589_11	1123065.ATWL01000021_gene3681	8.599e-132	438.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158351_k127_598589_7	882083.SacmaDRAFT_3483	8.775e-153	494.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4DXZS@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
SRR25158351_k127_598589_56	1229780.BN381_290119	2.326e-50	191.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,3UWW0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Arginine repressor, DNA binding domain	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158351_k127_598589_31	351607.Acel_1259	8.101e-83	301.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158351_k127_598589_14	1313172.YM304_20810	4.027e-126	429.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CMTH@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_598589_22	1313172.YM304_20800	2.834e-105	351.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158351_k127_598589_30	1161401.ASJA01000022_gene125	4.422e-84	306.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,43W6I@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158351_k127_598589_27	1229780.BN381_290123	4.833e-96	325.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,3UWGI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158351_k127_598589_6	1125863.JAFN01000001_gene1869	3.93e-164	559.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158351_k127_598589_23	1266914.ATUK01000016_gene390	5.186e-102	354.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1WXAD@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158351_k127_598589_67	1235799.C818_02232	5.65e-35	149.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,27I9A@186928|unclassified Lachnospiraceae	186801|Clostridia	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158351_k127_598589_63	1229780.BN381_290130	9.528e-42	160.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,3UWMY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158351_k127_598589_87	1229780.BN381_290131	1.66e-14	83.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,3UWZP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158351_k127_598589_52	446462.Amir_5473	1.877e-53	207.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DYUF@85010|Pseudonocardiales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158351_k127_598589_82	1313172.YM304_20630	1.035e-17	93.0	2FH85@1|root,3492H@2|Bacteria,2H8HQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_18	1313172.YM304_20600	4.213e-123	405.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CMTS@84992|Acidimicrobiia	84992|Acidimicrobiia	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158351_k127_598589_62	1444711.CCJF01000005_gene1640	1.965e-42	161.0	COG0054@1|root,COG0054@2|Bacteria,2JH0K@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158351_k127_598589_3	1229780.BN381_50160	3.967e-175	568.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,3UWF0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158351_k127_598589_53	1463936.JOJI01000003_gene779	1.877e-53	207.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158351_k127_598589_34	1048339.KB913029_gene4007	1.936e-80	282.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4ERIZ@85013|Frankiales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158351_k127_598589_57	1121877.JQKF01000023_gene2242	1.742e-48	178.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CN1Q@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158351_k127_598589_43	696281.Desru_2302	2.777e-62	237.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,260WX@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158351_k127_598589_36	1536772.R70723_13660	4.996e-75	269.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,26QFI@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SRR25158351_k127_598589_41	1231392.OCGS_1613	8.414e-68	248.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158351_k127_598589_49	1229780.BN381_50154	3.713e-55	199.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,3UWS7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158351_k127_598589_26	1229780.BN381_50152	1.182e-96	342.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,3UWAF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158351_k127_598589_4	525909.Afer_1692	1.195e-166	550.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CMSY@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158351_k127_598589_12	1313172.YM304_20510	4.867e-131	431.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CMYE@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158351_k127_598589_81	1313172.YM304_20500	4.339e-19	92.0	COG1758@1|root,COG1758@2|Bacteria,2HG9P@201174|Actinobacteria,4CN82@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158351_k127_598589_59	69042.WH5701_07884	3.084e-47	178.0	COG0194@1|root,COG0194@2|Bacteria,1G515@1117|Cyanobacteria,1GZ3I@1129|Synechococcus	1117|Cyanobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158351_k127_598589_74	1095772.CAHH01000042_gene1208	1.804e-26	113.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_598589_58	1121877.JQKF01000023_gene2254	2.107e-47	190.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria,4CNSK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158351_k127_598589_35	1313172.YM304_20470	3.864e-77	272.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CN0R@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158351_k127_598589_0	1229780.BN381_50144	0.0	1459.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,3UW8D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158351_k127_598589_17	1229780.BN381_50141	3.355e-124	424.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,3UWBX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
SRR25158351_k127_598589_10	1229780.BN381_50140	3.692e-137	450.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,3UWBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158351_k127_598589_21	1394178.AWOO02000063_gene44	3.982e-108	358.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4EH29@85012|Streptosporangiales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158351_k127_598589_46	1048339.KB913029_gene3972	6.984e-59	216.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4ESJQ@85013|Frankiales	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158351_k127_598589_70	485913.Krac_3174	3.05e-32	139.0	COG0617@1|root,COG0617@2|Bacteria,2G8X7@200795|Chloroflexi	200795|Chloroflexi	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	NTP_transf_5
SRR25158351_k127_598589_103	1449058.JQKT01000007_gene761	1.417e-07	64.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FNJ1@85023|Microbacteriaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_598589_19	1449353.JQMQ01000005_gene3520	1.859e-120	393.0	COG1028@1|root,COG1028@2|Bacteria,2GN6U@201174|Actinobacteria,2NGVI@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_598589_83	28444.JODQ01000011_gene3474	2.84e-17	88.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4EJ1I@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158351_k127_598589_68	1313172.YM304_38150	2.611e-34	140.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4CN8E@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158351_k127_598589_72	446462.Amir_5248	8.411e-31	127.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158351_k127_598589_38	525909.Afer_1713	3.048e-72	259.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158351_k127_598589_29	1206731.BAGB01000046_gene5658	2.278e-85	301.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FUMT@85025|Nocardiaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158351_k127_598589_61	1229780.BN381_50135	4.132e-46	170.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158351_k127_598589_33	446462.Amir_3296	6.831e-82	286.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4DXZV@85010|Pseudonocardiales	201174|Actinobacteria	E	3-dehydroquinate synthase	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829,ko:K16020	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R02412,R03083,R06592	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158351_k127_600513_29	292459.STH1949	7.062e-30	126.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
SRR25158351_k127_600513_7	281090.Lxx10950	6.439e-138	450.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4FMBD@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158351_k127_600513_27	290399.Arth_2919	7.68e-36	151.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria	201174|Actinobacteria	NOU	Peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
SRR25158351_k127_600513_20	1229780.BN381_50132	1.904e-51	200.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,3UWXN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158351_k127_600513_25	1313172.YM304_20310	2.001e-42	175.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CN7T@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158351_k127_600513_31	1120948.KB903240_gene3955	3.148e-20	104.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4E3CY@85010|Pseudonocardiales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158351_k127_600513_1	1313172.YM304_20290	1.929e-260	829.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CMTK@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158351_k127_600513_4	1313172.YM304_26410	3.993e-155	515.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158351_k127_600513_3	882086.SacxiDRAFT_0332	2.147e-178	583.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4E0SI@85010|Pseudonocardiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_600513_8	1313172.YM304_19970	2.025e-122	413.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CNBR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
SRR25158351_k127_600513_0	1313172.YM304_19960	2.453e-293	918.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CMVH@84992|Acidimicrobiia	84992|Acidimicrobiia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158351_k127_600513_14	351607.Acel_1340	7.829e-81	295.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4ERCU@85013|Frankiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158351_k127_600513_9	1121877.JQKF01000002_gene1672	5.004e-105	359.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CMXX@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
SRR25158351_k127_600513_32	526225.Gobs_3175	3.308e-15	79.0	COG1862@1|root,COG1862@2|Bacteria,2HKT2@201174|Actinobacteria,4ETJY@85013|Frankiales	201174|Actinobacteria	U	Preprotein translocase, YajC subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158351_k127_600513_6	1229780.BN381_50110	8.826e-142	457.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,3UWC6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158351_k127_600513_23	1313172.YM304_19870	2.152e-47	185.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CNA0@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158351_k127_600513_26	1229780.BN381_50108	6.664e-41	167.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,3UWKV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158351_k127_600513_16	365528.KB891269_gene5983	1.846e-63	227.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4ESNJ@85013|Frankiales	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158351_k127_600513_24	251229.Chro_2160	1.016e-46	179.0	COG2068@1|root,COG2068@2|Bacteria,1G608@1117|Cyanobacteria,3VKPE@52604|Pleurocapsales	1117|Cyanobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158351_k127_600513_10	1313172.YM304_33320	1.855e-96	326.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CMQN@84992|Acidimicrobiia	84992|Acidimicrobiia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158351_k127_600513_15	28042.GU90_16815	1.945e-71	244.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E49V@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158351_k127_600513_18	479432.Sros_8570	1.977e-56	201.0	COG5015@1|root,COG5015@2|Bacteria,2I3I5@201174|Actinobacteria,4EJIN@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_600513_12	525909.Afer_1219	1.669e-92	315.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CMY7@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158351_k127_600513_21	1381751.JAJB01000028_gene1381	4.397e-51	187.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4F9XX@85019|Brevibacteriaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158351_k127_600513_5	1313172.YM304_19820	4.096e-144	461.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CMSX@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158351_k127_600513_19	525909.Afer_1400	5.878e-52	202.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4CN8S@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158351_k127_600513_11	1313172.YM304_19800	6.088e-96	323.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CNA7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_600513_17	1313172.YM304_19790	1.301e-57	219.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria	201174|Actinobacteria	J	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158351_k127_600513_13	1313172.YM304_19780	1.055e-86	311.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CN3N@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158351_k127_600513_22	1229780.BN381_50175	1.747e-50	192.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,3UXIQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158351_k127_600513_28	1121877.JQKF01000002_gene1645	1.529e-30	134.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CN1P@84992|Acidimicrobiia	84992|Acidimicrobiia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_600513_2	635013.TherJR_2206	8.832e-182	595.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,260DZ@186807|Peptococcaceae	186801|Clostridia	J	TIGRFAM Translation elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_600513_33	1396418.BATQ01000185_gene2114	1.278e-13	81.0	COG1404@1|root,COG3386@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Exo_endo_phos,Glyco_hydro_25,NHL,Peptidase_S8,SLH,TIG
SRR25158351_k127_600513_30	326424.FRAAL2683	1.284e-27	117.0	2C5HV@1|root,33SI2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_600513_34	1229780.BN381_50173	1.226e-07	54.0	2F9Q3@1|root,34209@2|Bacteria,2H616@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_604925_5	1123023.JIAI01000005_gene521	6.917e-15	81.0	COG0500@1|root,COG0500@2|Bacteria,2IMJ3@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_604925_3	682795.AciX8_3927	9.324e-38	160.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158351_k127_604925_0	1041522.MCOL_V210000	4.869e-167	537.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,235XV@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_604925_2	35754.JNYJ01000003_gene6551	2.447e-75	261.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria,4D9VJ@85008|Micromonosporales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	araD	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158351_k127_604925_1	35754.JNYJ01000003_gene6567	2.417e-159	526.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4DMI0@85008|Micromonosporales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_604925_4	591001.Acfer_0420	6.131e-25	107.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158351_k127_610354_30	1229780.BN381_450016	3.349e-77	265.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,3UX9K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	menJ	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158351_k127_610354_61	1229780.BN381_450013	2.199e-16	88.0	2C3UQ@1|root,341WW@2|Bacteria,2H6NT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_36	1229780.BN381_450012	9.677e-67	229.0	COG1143@1|root,COG1143@2|Bacteria,2H4NQ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
SRR25158351_k127_610354_10	1229780.BN381_450011	1.002e-137	443.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158351_k127_610354_25	1229780.BN381_450010	1.663e-88	303.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158351_k127_610354_41	1229780.BN381_450009	1.186e-58	214.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158351_k127_610354_46	1313172.YM304_04040	5.767e-50	194.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158351_k127_610354_62	1313172.YM304_04050	2.353e-16	89.0	2FE68@1|root,34663@2|Bacteria,2H83B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_47	246196.MSMEI_6492	7.282e-48	186.0	COG1524@1|root,COG1524@2|Bacteria,2HSIU@201174|Actinobacteria,23CG7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158351_k127_610354_12	883.DvMF_2502	2.871e-134	441.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,2M8AM@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_610354_14	1394178.AWOO02000038_gene9104	2.914e-132	428.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4EHK2@85012|Streptosporangiales	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158351_k127_610354_9	42256.RradSPS_1755	3.421e-141	464.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158351_k127_610354_33	1229780.BN381_60042	3.56e-71	252.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,3UWP6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158351_k127_610354_23	867903.ThesuDRAFT_01613	3.098e-97	344.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158351_k127_610354_58	1121428.DESHY_10149___1	6.245e-30	138.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,2625C@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158351_k127_610354_29	351607.Acel_0239	2.998e-77	265.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4ESER@85013|Frankiales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158351_k127_610354_73	479432.Sros_0545	2.143e-06	59.0	COG1359@1|root,COG1359@2|Bacteria,2HINW@201174|Actinobacteria,4EI7M@85012|Streptosporangiales	201174|Actinobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158351_k127_610354_64	591158.SSMG_02969	1.506e-15	82.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_610354_72	1032480.MLP_48040	3.282e-09	69.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DN25@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_610354_37	1313172.YM304_37870	7.208e-62	229.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158351_k127_610354_66	351607.Acel_0244	4.644e-13	81.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,4ET9D@85013|Frankiales	201174|Actinobacteria	K	DNA binding domain protein, excisionase family	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158351_k127_610354_70	351607.Acel_0245	3.645e-10	74.0	2EBHZ@1|root,335IE@2|Bacteria,2GNMR@201174|Actinobacteria,4EV8Z@85013|Frankiales	201174|Actinobacteria	S	Phosphatase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	-	-	-	-	-	-	-	-	-	Phosphatase
SRR25158351_k127_610354_38	269800.Tfu_2708	2.897e-61	220.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4EHTN@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158351_k127_610354_65	561175.KB894099_gene4995	1.209e-13	78.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4EIHS@85012|Streptosporangiales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158351_k127_610354_18	1313172.YM304_37900	3.977e-107	361.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4CMYV@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_610354_54	1906.SFRA_17240	7.976e-37	141.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158351_k127_610354_71	457429.ABJI02000426_gene964	1.343e-09	66.0	2DP8R@1|root,32UKH@2|Bacteria,2IFBP@201174|Actinobacteria	201174|Actinobacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_68	1229780.BN381_60052	9.492e-13	74.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158351_k127_610354_50	1223544.GSI01S_05_00320	4.83e-43	164.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4GDX3@85026|Gordoniaceae	201174|Actinobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158351_k127_610354_51	1123024.AUII01000002_gene1155	2.465e-40	161.0	COG2912@1|root,COG2912@2|Bacteria,2GMER@201174|Actinobacteria,4EARR@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158351_k127_610354_56	1229780.BN381_100221	2.358e-32	132.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158351_k127_610354_60	1313172.YM304_02480	5.411e-23	112.0	COG0526@1|root,COG0526@2|Bacteria,2H8ZP@201174|Actinobacteria	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_57	997346.HMPREF9374_3435	3.538e-31	132.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,27C7P@186824|Thermoactinomycetaceae	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158351_k127_610354_32	1123321.KB905820_gene5484	1.218e-75	278.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158351_k127_610354_42	263358.VAB18032_10520	1.259e-56	211.0	2DE9Z@1|root,32U2Z@2|Bacteria,2ID6V@201174|Actinobacteria,4DBZW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_43	649831.L083_1624	3.702e-56	219.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4D9QD@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	scbA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158351_k127_610354_44	644966.Tmar_1973	3.71e-56	205.0	COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,25B2N@186801|Clostridia	186801|Clostridia	P	Abc transporter	mntA	-	3.6.3.35	ko:K09817,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00242,M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158351_k127_610354_35	561175.KB894094_gene1607	4.175e-67	240.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4EI6R@85012|Streptosporangiales	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158351_k127_610354_55	1313172.YM304_31100	9.356e-35	147.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158351_k127_610354_49	1283287.KB822578_gene2539	4.647e-44	170.0	COG1028@1|root,COG1028@2|Bacteria,2IC24@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_610354_40	40571.JOEA01000009_gene3377	1.12e-58	213.0	COG1082@1|root,COG1082@2|Bacteria,2GQ0M@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158351_k127_610354_45	58123.JOFJ01000021_gene3979	4.581e-52	197.0	COG1028@1|root,COG1028@2|Bacteria,2GVVR@201174|Actinobacteria,4EPHJ@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_610354_52	1381751.JAJB01000068_gene339	1.964e-39	152.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,4FA60@85019|Brevibacteriaceae	201174|Actinobacteria	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158351_k127_610354_27	1370125.AUWT01000020_gene4723	5.919e-83	305.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,232G4@1762|Mycobacteriaceae	201174|Actinobacteria	E	inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158351_k127_610354_19	1229780.BN381_430025	6.017e-107	354.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,3UWG9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG1176 ABC-type spermidine putrescine transport system, permease component I	potH	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158351_k127_610354_26	35754.JNYJ01000050_gene7962	3.012e-87	318.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4D9ZP@85008|Micromonosporales	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158351_k127_610354_8	164757.Mjls_2606	1.581e-147	478.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,2329P@1762|Mycobacteriaceae	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158351_k127_610354_2	1229780.BN381_430022	3.004e-219	691.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,3UWEA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.19	ko:K00137	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R02549	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158351_k127_610354_13	1043493.BBLU01000008_gene404	4.352e-134	442.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria	201174|Actinobacteria	H	Aminotransferase	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_610354_11	518766.Rmar_0424	1.744e-137	458.0	COG0025@1|root,COG0569@1|root,COG1762@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,4PKJ5@976|Bacteroidetes,1FIVS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158351_k127_610354_15	471852.Tcur_3975	1.81e-118	396.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4EM9F@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_1	1380356.JNIK01000017_gene2822	4.806e-248	795.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4ETP4@85013|Frankiales	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3,1.5.99.4	ko:K03520,ko:K19820	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158351_k127_610354_34	1206731.BAGB01000047_gene5302	4.779e-68	244.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4FWH1@85025|Nocardiaceae	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3,1.5.99.4	ko:K03518,ko:K19819	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158351_k127_610354_24	298654.FraEuI1c_2746	4.047e-94	317.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158351_k127_610354_28	1313172.YM304_11240	6.037e-80	275.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CNYM@84992|Acidimicrobiia	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_610354_21	44454.NF84_12315	1.731e-99	341.0	COG0451@1|root,COG0451@2|Bacteria,2I9DG@201174|Actinobacteria,237C3@1762|Mycobacteriaceae	201174|Actinobacteria	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158351_k127_610354_53	1219045.BV98_001309	2.471e-37	153.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,2U5BV@28211|Alphaproteobacteria,2KDFM@204457|Sphingomonadales	204457|Sphingomonadales	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_610354_6	1394178.AWOO02000002_gene1621	2.242e-158	535.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,4EH0H@85012|Streptosporangiales	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_22	706587.Desti_3650	1.864e-98	352.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MQ47@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
SRR25158351_k127_610354_17	1229780.BN381_350072	3.873e-111	373.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,3UXC7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class I and II	bioF	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.47,6.2.1.14	ko:K00652,ko:K01906	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03209,R03210,R10124	RC00004,RC00014,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv1569	Aminotran_1_2
SRR25158351_k127_610354_48	882082.SaccyDRAFT_2707	8.217e-45	183.0	COG0132@1|root,COG0132@2|Bacteria,2H6DY@201174|Actinobacteria	201174|Actinobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_26
SRR25158351_k127_610354_16	1229780.BN381_430010	9.2e-116	387.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158351_k127_610354_39	351607.Acel_1286	6.84e-61	214.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4ESI6@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158351_k127_610354_3	351607.Acel_1287	6.224e-198	628.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4ERWH@85013|Frankiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158351_k127_610354_5	1229780.BN381_430028	6.673e-160	516.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,3UWER@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158351_k127_610354_7	266117.Rxyl_0904	2.582e-153	500.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158351_k127_610354_74	1123507.ATVQ01000001_gene1631	2.392e-06	58.0	2BD34@1|root,326QM@2|Bacteria,2HC94@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_63	446470.Snas_5979	3.083e-16	88.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F061@85014|Glycomycetales	201174|Actinobacteria	L	Helix-turn-helix domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158351_k127_610354_20	543632.JOJL01000017_gene10037	2.171e-104	353.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4DASB@85008|Micromonosporales	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158351_k127_610354_4	298654.FraEuI1c_7084	9.309e-172	552.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4ERIS@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158351_k127_610354_67	1160718.SU9_33428	4.885e-13	78.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158351_k127_610354_0	1229780.BN381_130019	4.286e-256	811.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158351_k127_610354_59	1313172.YM304_38910	3.927e-27	115.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_610354_31	1229780.BN381_130016	7.49e-77	263.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,3UWG1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158351_k127_612089_24	1449069.JMLO01000029_gene4894	5.18e-22	101.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4G445@85025|Nocardiaceae	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_612089_30	258533.BN977_04130	0.0006704	50.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158351_k127_612089_11	410359.Pcal_1311	6.569e-68	252.0	COG1064@1|root,arCOG01455@2157|Archaea,2XQ4K@28889|Crenarchaeota	28889|Crenarchaeota	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_612089_22	298655.KI912267_gene7793	1.14e-37	158.0	COG4188@1|root,COG4188@2|Bacteria,2I9HM@201174|Actinobacteria	201174|Actinobacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,PAF-AH_p_II
SRR25158351_k127_612089_20	285535.JOEY01000056_gene6754	1.301e-52	209.0	COG1024@1|root,COG1024@2|Bacteria,2GN69@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_612089_28	440512.C211_12756	1.501e-09	65.0	COG0664@1|root,COG0664@2|Bacteria,1RKRH@1224|Proteobacteria,1S42Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158351_k127_612089_26	37919.EP51_22300	5.333e-12	78.0	COG0515@1|root,COG2197@1|root,COG3903@1|root,COG0515@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
SRR25158351_k127_612089_0	1206720.BAFQ01000058_gene1495	4.971e-170	546.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4FW3Q@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_612089_21	1229780.BN381_130302	1.247e-39	149.0	2E6D6@1|root,3310T@2|Bacteria,2H7NK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_612089_4	1144275.COCOR_06542	7.099e-116	394.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_612089_6	1054860.KB913030_gene2748	2.917e-99	332.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158351_k127_612089_10	234621.RER_50980	1.183e-79	278.0	COG1028@1|root,COG1028@2|Bacteria,2GMF5@201174|Actinobacteria,4FYXK@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_612089_17	1265310.CCBD010000007_gene2956	1.704e-57	211.0	COG1024@1|root,COG1024@2|Bacteria,2I9MR@201174|Actinobacteria,2373R@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA8_1	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_612089_19	2002.JOEQ01000015_gene5113	2.628e-55	204.0	COG1028@1|root,COG1028@2|Bacteria,2GRE4@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG_2	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_612089_23	1121019.AUMN01000009_gene1868	7.677e-36	141.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158351_k127_612089_29	298655.KI912267_gene6636	6.854e-06	57.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_612089_2	502558.EGYY_18230	1.947e-148	510.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia	84998|Coriobacteriia	C	NADH flavin oxidoreductase	-	-	1.3.1.31,1.3.1.34	ko:K00219,ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158351_k127_612089_5	1078020.KEK_19591	7.741e-112	400.0	COG2124@1|root,COG2124@2|Bacteria,2GMD0@201174|Actinobacteria,236UQ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_612089_14	56110.Oscil6304_5208	3.021e-66	242.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_612089_25	1386089.N865_18765	5.308e-20	99.0	2E7YB@1|root,332CR@2|Bacteria,2IRTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
SRR25158351_k127_612089_12	463191.SSEG_08603	6.776e-68	245.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_612089_1	1123320.KB889689_gene530	8.537e-168	550.0	COG0318@1|root,COG0318@2|Bacteria,2GKZ6@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD17	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_612089_8	1333998.M2A_1342	2.553e-86	314.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,4BRGS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	MA20_01275	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158351_k127_612089_3	365528.KB891283_gene3355	4.089e-118	407.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EX8X@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_612089_27	1207076.ALAT01000017_gene933	1.978e-11	72.0	COG3631@1|root,COG3631@2|Bacteria,1NPDR@1224|Proteobacteria	1224|Proteobacteria	S	Phenazine biosynthesis protein A/B	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158351_k127_612089_7	47763.JNZA01000039_gene1698	8.136e-88	319.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_612089_15	1206731.BAGB01000047_gene5200	3.545e-64	237.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4FXFM@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_612089_13	292.DM42_6063	1.19e-67	250.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2VHVJ@28216|Betaproteobacteria,1K7E4@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_612089_16	479432.Sros_8264	5.282e-63	231.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4EHQ6@85012|Streptosporangiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_612089_9	1229780.BN381_80314	2.123e-84	304.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,3UXSW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158351_k127_612089_18	1240350.AMZE01000086_gene4370	2.86e-56	203.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_631225_27	1123065.ATWL01000011_gene92	2.133e-05	50.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158351_k127_631225_7	1122939.ATUD01000003_gene3637	1.232e-131	432.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria,4CRXS@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_631225_23	1313172.YM304_21360	3.879e-15	78.0	29B43@1|root,2ZY2Q@2|Bacteria,2HD3P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_631225_14	1380356.JNIK01000005_gene919	7.916e-66	233.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4ESDD@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158351_k127_631225_4	215803.DB30_1070	2.869e-186	618.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2YTYU@29|Myxococcales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158351_k127_631225_25	1463861.JNXE01000008_gene9614	5.352e-12	77.0	COG4424@1|root,COG4424@2|Bacteria,2GNGY@201174|Actinobacteria	201174|Actinobacteria	S	carbohydrate metabolic process	stf0	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
SRR25158351_k127_631225_22	1211815.CBYP010000006_gene276	2.238e-19	103.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_631225_16	1229780.BN381_100036	1.293e-57	218.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25,Methyltransf_31
SRR25158351_k127_631225_3	1229780.BN381_80408	6.684e-196	625.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,3UW6D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal protein S1-like RNA-binding domain	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158351_k127_631225_26	1408419.JHYG01000001_gene1636	2.906e-10	70.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,2JTIY@204441|Rhodospirillales	204441|Rhodospirillales	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158351_k127_631225_20	1229780.BN381_80410	2.01e-48	188.0	COG4963@1|root,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,3UXHE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	NUBPL iron-transfer P-loop NTPase	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
SRR25158351_k127_631225_5	1298863.AUEP01000018_gene3827	2.035e-170	546.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4DPMF@85009|Propionibacteriales	201174|Actinobacteria	U	Type II/IV secretion system protein	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158351_k127_631225_21	397278.JOJN01000004_gene1179	1.449e-47	186.0	COG2304@1|root,COG4965@1|root,COG2304@2|Bacteria,COG4965@2|Bacteria,2H577@201174|Actinobacteria,4DQ0A@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF,VWA_2
SRR25158351_k127_631225_19	401526.TcarDRAFT_1916	4.835e-52	207.0	COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,4H46H@909932|Negativicutes	909932|Negativicutes	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158351_k127_631225_8	1394178.AWOO02000002_gene1917	6.33e-127	423.0	COG1287@1|root,COG1287@2|Bacteria,2H0CC@201174|Actinobacteria	201174|Actinobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_631225_29	2045.KR76_11035	0.0009065	44.0	COG3847@1|root,COG3847@2|Bacteria,2GX2Y@201174|Actinobacteria,4DW19@85009|Propionibacteriales	201174|Actinobacteria	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
SRR25158351_k127_631225_17	365528.KB891219_gene1034	2.675e-57	209.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4ESVT@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158351_k127_631225_1	1229780.BN381_420007	1.006e-284	889.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,3UWC3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158351_k127_631225_0	298653.Franean1_2057	0.0	1374.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ERXD@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158351_k127_631225_13	1313172.YM304_21650	4.623e-82	280.0	COG0500@1|root,COG2226@2|Bacteria,2HG5Z@201174|Actinobacteria,4CN2W@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_631225_6	1229780.BN381_410040	2.669e-168	554.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,3UWB7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158351_k127_631225_2	1229780.BN381_50096	4.965e-232	754.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,3UWEG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158351_k127_631225_12	298655.KI912267_gene7040	4.462e-97	325.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4EREI@85013|Frankiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158351_k127_631225_15	1273125.Rrhod_2864	1.1e-64	236.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4FUHS@85025|Nocardiaceae	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158351_k127_631225_9	391037.Sare_3325	1.583e-124	407.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D98B@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158351_k127_631225_10	867903.ThesuDRAFT_00613	4.41e-113	403.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WCWM@538999|Clostridiales incertae sedis	186801|Clostridia	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158351_k127_631225_11	1229780.BN381_80403	1.334e-99	336.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,3UWH0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158351_k127_631225_24	1121877.JQKF01000028_gene2137	1.017e-14	76.0	COG1314@1|root,COG1314@2|Bacteria,2HGDT@201174|Actinobacteria,4CNCC@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158351_k127_631225_18	1123320.KB889664_gene1264	3.214e-53	202.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158351_k127_638015_1	1343740.M271_39495	2.921e-230	722.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158351_k127_638015_0	365528.KB891210_gene2148	6.807e-274	871.0	COG0183@1|root,COG1545@1|root,COG0183@2|Bacteria,COG1545@2|Bacteria,2IETY@201174|Actinobacteria,4EXA5@85013|Frankiales	201174|Actinobacteria	I	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_638015_9	330084.JNYZ01000046_gene1914	1.875e-150	496.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria	201174|Actinobacteria	P	Flavoprotein involved in K transport	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_2,Pyr_redox_3
SRR25158351_k127_638015_8	1160137.KB907309_gene5309	8.868e-157	511.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4FVFU@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_638015_20	1957.JODX01000019_gene1530	1.197e-48	182.0	COG1309@1|root,COG1309@2|Bacteria,2GNJZ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_638015_19	1380356.JNIK01000015_gene2448	1.544e-50	187.0	COG2128@1|root,COG2128@2|Bacteria,2II1N@201174|Actinobacteria,4EVJM@85013|Frankiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_638015_17	298653.Franean1_3305	1.722e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_638015_15	298653.Franean1_2973	2.027e-99	339.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4ES18@85013|Frankiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain protein	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158351_k127_638015_3	285535.JOEY01000006_gene8113	7.832e-203	641.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158351_k127_638015_23	1172185.KB911525_gene3992	2.151e-32	136.0	2EUA2@1|root,33MSG@2|Bacteria,2IMWS@201174|Actinobacteria,4G233@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_638015_2	285535.JOEY01000006_gene8115	3.389e-210	660.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158351_k127_638015_14	1370120.AUWR01000002_gene3667	6.696e-113	372.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,234YE@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_638015_24	1206744.BAGL01000058_gene1940	4.442e-32	141.0	COG4319@1|root,COG4319@2|Bacteria,2IFX9@201174|Actinobacteria,4G0HN@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_638015_11	285535.JOEY01000006_gene8159	3.636e-129	445.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_638015_5	365528.KB891262_gene5089	5.642e-183	597.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_638015_6	1123319.AUBE01000002_gene1483	2.48e-179	585.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD16	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_638015_18	1056816.JAFQ01000004_gene4980	1.99e-66	246.0	COG1960@1|root,COG1960@2|Bacteria,2HQGI@201174|Actinobacteria,4FW8Y@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
SRR25158351_k127_638015_7	1206735.BAGG01000265_gene6935	1.026e-172	548.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FX1Q@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_638015_16	1206720.BAFQ01000293_gene6383	1.56e-98	331.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4FUZE@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_638015_10	1206735.BAGG01000265_gene6897	2.992e-141	468.0	COG1960@1|root,COG1960@2|Bacteria,2GKYN@201174|Actinobacteria,4FVVF@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_638015_21	487521.OCU_13200	3.269e-40	171.0	COG1960@1|root,COG1960@2|Bacteria,2GM6Q@201174|Actinobacteria,236IZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
SRR25158351_k127_638015_4	222534.KB893728_gene5638	7.255e-188	595.0	COG2124@1|root,COG2124@2|Bacteria,2GNZS@201174|Actinobacteria,4EUB3@85013|Frankiales	201174|Actinobacteria	Q	PFAM Cytochrome P450	cyp150A5	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_638015_12	298654.FraEuI1c_3890	1.597e-122	398.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria,4EVT2@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_638015_13	1207063.P24_07784	3.763e-119	394.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	tauD	-	1.14.11.17	ko:K03119,ko:K22303	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
SRR25158351_k127_638015_22	298655.KI912266_gene3277	9.137e-38	144.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU1V@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_684850_2	1123320.KB889664_gene1264	7.24e-60	218.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158351_k127_684850_1	1445613.JALM01000074_gene6663	7.079e-82	284.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DXT5@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158351_k127_684850_0	797209.ZOD2009_01020	3.037e-91	306.0	COG0444@1|root,arCOG00181@2157|Archaea,2XSTM@28890|Euryarchaeota,23SR3@183963|Halobacteria	183963|Halobacteria	E	COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158351_k127_689114_2	401526.TcarDRAFT_2676	1.168e-190	620.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4H232@909932|Negativicutes	909932|Negativicutes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158351_k127_689114_14	1380356.JNIK01000021_gene4454	5.903e-80	292.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_689114_11	1415166.NONO_c36340	2.162e-112	371.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FX46@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_689114_17	298653.Franean1_4849	6.378e-74	267.0	COG0477@1|root,COG2814@2|Bacteria,2H1TJ@201174|Actinobacteria,4EUWV@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_689114_33	1229780.BN381_10089	1.945e-20	107.0	COG3255@1|root,COG3255@2|Bacteria,2H0GP@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_689114_29	351607.Acel_0696	1.572e-25	109.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4ESZM@85013|Frankiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158351_k127_689114_3	1229780.BN381_10093	5.872e-190	609.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,3UWA6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158351_k127_689114_6	429009.Adeg_1097	4.738e-139	458.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158351_k127_689114_27	1121406.JAEX01000033_gene2085	1.024e-37	150.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,42TQP@68525|delta/epsilon subdivisions,2WRPZ@28221|Deltaproteobacteria,2MC5U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158351_k127_689114_1	1313172.YM304_33670	5.254e-258	807.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CMQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158351_k127_689114_19	1283299.AUKG01000002_gene4329	9.859e-72	253.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria,4CPW5@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158351_k127_689114_0	1121877.JQKF01000003_gene1461	1.023e-267	836.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CMWQ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_689114_24	1229780.BN381_80040	2.703e-49	192.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,3UWJX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ACT domain	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158351_k127_689114_4	1313172.YM304_11450	1.742e-144	477.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CMV2@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158351_k127_689114_26	1313172.YM304_38800	3.428e-42	162.0	COG0344@1|root,COG0344@2|Bacteria,2IFX1@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158351_k127_689114_23	1313172.YM304_38790	3.252e-50	191.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria	201174|Actinobacteria	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158351_k127_689114_37	1202532.FF52_13371	3.293e-07	58.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia,2NWE0@237|Flavobacterium	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158351_k127_689114_31	675635.Psed_1292	1.012e-21	99.0	COG1225@1|root,COG1225@2|Bacteria,2H8VQ@201174|Actinobacteria	201174|Actinobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158351_k127_689114_12	65093.PCC7418_3088	1.085e-108	373.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_689114_30	292459.STH1575	8.574e-25	119.0	2CIU6@1|root,32S8H@2|Bacteria,1VBBK@1239|Firmicutes,24PGQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_689114_10	562970.Btus_1735	1.791e-120	418.0	COG3185@1|root,COG3185@2|Bacteria,1TQT2@1239|Firmicutes,4HDI8@91061|Bacilli	91061|Bacilli	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158351_k127_689114_7	216594.MMAR_3565	3.843e-135	445.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,234NV@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158351_k127_689114_5	66875.JODY01000006_gene2209	1.061e-140	462.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158351_k127_689114_32	1120948.KB903244_gene2941	2.35e-21	104.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4E1C7@85010|Pseudonocardiales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158351_k127_689114_36	1429046.RR21198_1404	8.603e-08	63.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FVM6@85025|Nocardiaceae	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158351_k127_689114_20	1236902.ANAS01000001_gene1830	3.395e-59	222.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4EIDY@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_689114_8	219305.MCAG_04305	1.178e-126	412.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4DHNE@85008|Micromonosporales	201174|Actinobacteria	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_689114_16	1380356.JNIK01000018_gene720	2.597e-77	269.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4ESBC@85013|Frankiales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158351_k127_689114_22	526225.Gobs_4563	3.995e-56	217.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4ES3B@85013|Frankiales	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158351_k127_689114_25	1313172.YM304_23990	2.725e-43	168.0	COG2267@1|root,COG2267@2|Bacteria,2GYP0@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR25158351_k127_689114_9	1343740.M271_03650	9.154e-125	420.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158351_k127_689114_13	448385.sce5042	9.805e-81	285.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,42S21@68525|delta/epsilon subdivisions,2WNRS@28221|Deltaproteobacteria,2YUP2@29|Myxococcales	28221|Deltaproteobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158351_k127_689114_21	1313172.YM304_24030	1.292e-58	215.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CN6D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158351_k127_689114_34	67352.JODS01000002_gene1465	2.08e-18	94.0	COG0789@1|root,COG0789@2|Bacteria,2GKSZ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158351_k127_689114_18	1280941.HY2_14325	1.318e-73	256.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,43WPX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
SRR25158351_k127_689114_15	215803.DB30_0464	1.717e-77	275.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158351_k127_689114_35	68170.KL590483_gene5649	3.17e-10	64.0	2DN49@1|root,32VFI@2|Bacteria,2IMED@201174|Actinobacteria,4E3ZX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_697544_44	1229780.BN381_130143	4.347e-10	63.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_697544_30	1229780.BN381_100086	6.226e-45	168.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	mazF3	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158351_k127_697544_45	1157943.KB892705_gene1538	6.176e-07	57.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,233TP@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
SRR25158351_k127_697544_32	1298864.AUEQ01000006_gene4875	8.663e-43	171.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,233TP@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
SRR25158351_k127_697544_47	1449048.JQKU01000006_gene4985	0.0001682	46.0	COG0577@1|root,COG0577@2|Bacteria,2HNFQ@201174|Actinobacteria,234N9@1762|Mycobacteriaceae	201174|Actinobacteria	V	FtsX-like permease family	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_697544_46	1370120.AUWR01000040_gene69	1.897e-05	49.0	COG0577@1|root,COG0577@2|Bacteria,2HNFQ@201174|Actinobacteria,234N9@1762|Mycobacteriaceae	201174|Actinobacteria	V	FtsX-like permease family	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_697544_15	1137799.GZ78_13235	1.55e-91	319.0	COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,1S3XA@1236|Gammaproteobacteria,1XP55@135619|Oceanospirillales	135619|Oceanospirillales	I	COG0183 Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
SRR25158351_k127_697544_13	47839.CCAU010000011_gene5647	9.628e-111	378.0	COG2124@1|root,COG2124@2|Bacteria,2HSPE@201174|Actinobacteria,2353U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_697544_42	1278078.G419_02380	1.168e-15	89.0	COG1309@1|root,COG1309@2|Bacteria,2II8V@201174|Actinobacteria,4G1NW@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_697544_43	1123368.AUIS01000001_gene1864	1.48e-11	77.0	COG1315@1|root,COG1315@2|Bacteria	2|Bacteria	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
SRR25158351_k127_697544_22	1121877.JQKF01000002_gene1731	9.154e-66	233.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CNHE@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158351_k127_697544_23	83332.Rv0577	9.782e-64	234.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,23F0E@1762|Mycobacteriaceae	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158351_k127_697544_9	1229780.BN381_640016	9.479e-127	416.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	bglIM	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158351_k127_697544_20	1464048.JNZS01000013_gene3159	1.455e-76	280.0	COG1120@1|root,COG1120@2|Bacteria,2IA4F@201174|Actinobacteria,4DA8F@85008|Micromonosporales	201174|Actinobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158351_k127_697544_11	219305.MCAG_03154	4.78e-118	392.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4D9B0@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158351_k127_697544_19	1123320.KB889580_gene1692	2.218e-77	269.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158351_k127_697544_2	1313172.YM304_29200	8.387e-172	565.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CNI7@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_697544_6	365528.KB891192_gene3593	1.998e-138	461.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ES40@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_697544_29	479432.Sros_2092	1.545e-49	185.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria,4EJ93@85012|Streptosporangiales	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
SRR25158351_k127_697544_21	1313172.YM304_14700	1.729e-68	245.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158351_k127_697544_17	235985.BBPN01000009_gene3713	1.369e-84	295.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,2NHGS@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_697544_10	1449346.JQMO01000003_gene6815	9.261e-122	398.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,2M433@2063|Kitasatospora	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_697544_25	68260.JOAY01000003_gene4553	5.305e-54	194.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158351_k127_697544_18	1313172.YM304_14250	2.948e-82	276.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CMYB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_697544_7	298655.KI912266_gene1976	4.426e-135	440.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4ERSI@85013|Frankiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_697544_1	1313172.YM304_02620	1.618e-205	688.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CMW8@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_697544_39	298653.Franean1_0817	3.897e-20	104.0	COG2845@1|root,COG2845@2|Bacteria,2GU62@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
SRR25158351_k127_697544_0	1229780.BN381_210057	1.445e-208	661.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_697544_8	1121877.JQKF01000003_gene1497	6.498e-130	421.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CNND@84992|Acidimicrobiia	84992|Acidimicrobiia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158351_k127_697544_34	485913.Krac_1516	6.788e-29	126.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_697544_40	1313172.YM304_13970	8.818e-20	99.0	2FJ53@1|root,34AVA@2|Bacteria,2H8CM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_697544_38	351607.Acel_2096	1.898e-21	110.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	GO:0005575,GO:0005576	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158351_k127_697544_12	675635.Psed_1534	2.324e-111	370.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158351_k127_697544_36	1232429.CBLL010000110_gene2321	7.557e-26	123.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,1W9S8@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158351_k127_697544_33	1380390.JIAT01000010_gene4588	9.15e-36	143.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4CQPF@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158351_k127_697544_5	926550.CLDAP_06280	1.151e-139	452.0	COG2141@1|root,COG3255@1|root,COG2141@2|Bacteria,COG3255@2|Bacteria,2G878@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_697544_26	1077144.AGFF01000023_gene1383	2.311e-50	198.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158351_k127_697544_28	448385.sce5152	1.372e-49	189.0	COG1072@1|root,COG1072@2|Bacteria,1MV3M@1224|Proteobacteria,438MB@68525|delta/epsilon subdivisions,2X3VI@28221|Deltaproteobacteria,2YX93@29|Myxococcales	28221|Deltaproteobacteria	F	pantothenate kinase activity	coaA	-	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158351_k127_697544_35	1206733.BAGC01000040_gene1453	7.499e-28	123.0	COG5517@1|root,COG5517@2|Bacteria,2IIIU@201174|Actinobacteria,4G0YC@85025|Nocardiaceae	201174|Actinobacteria	Q	Ring hydroxylating beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_697544_16	450851.PHZ_c2748	3.283e-91	314.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2U3GM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_697544_27	72019.SARC_06571T0	2.373e-50	187.0	COG1011@1|root,COG3173@1|root,KOG1469@2759|Eukaryota,KOG3085@2759|Eukaryota,38BWX@33154|Opisthokonta	33154|Opisthokonta	I	very-long-chain-acyl-CoA dehydrogenase activity	ACAD10	GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.3.8.7	ko:K00249,ko:K11729	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,HAD_2,Hydrolase
SRR25158351_k127_697544_31	1313172.YM304_20180	1.839e-43	173.0	COG0406@1|root,COG0406@2|Bacteria,2GM22@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158351_k127_697544_14	391625.PPSIR1_27873	1.963e-97	331.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,42PZ0@68525|delta/epsilon subdivisions,2WM9Y@28221|Deltaproteobacteria,2YUF3@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_697544_4	1440053.JOEI01000004_gene3867	2.326e-151	494.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158351_k127_697544_24	215803.DB30_7768	2.573e-59	211.0	COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,4351D@68525|delta/epsilon subdivisions,2X948@28221|Deltaproteobacteria,2Z1TW@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158351_k127_697544_3	2002.JOEQ01000003_gene2343	5.272e-164	531.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EG8G@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_697544_37	1120948.KB903246_gene3332	3.441e-23	109.0	COG0644@1|root,COG0644@2|Bacteria,2HRCE@201174|Actinobacteria,4EAHQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_716806_0	298654.FraEuI1c_2358	0.0	1197.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERJ2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158351_k127_716806_32	1229780.BN381_510003	1.84e-72	259.0	COG1824@1|root,COG1824@2|Bacteria,2H441@201174|Actinobacteria	201174|Actinobacteria	P	Integral membrane	-	-	-	-	-	-	-	-	-	-	-	-	MgtE
SRR25158351_k127_716806_6	1229780.BN381_80206	4.965e-149	482.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
SRR25158351_k127_716806_2	1179773.BN6_44150	1.389e-245	798.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E15N@85010|Pseudonocardiales	201174|Actinobacteria	P	E1-E2 ATPase	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158351_k127_716806_36	656024.FsymDg_3552	5.258e-68	241.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4ESQG@85013|Frankiales	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158351_k127_716806_44	479432.Sros_0414	1.686e-40	162.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4EHN9@85012|Streptosporangiales	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158351_k127_716806_57	1463921.JODF01000012_gene275	3.848e-06	58.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_716806_28	1463821.JOGR01000010_gene3770	8.184e-87	301.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158351_k127_716806_29	436229.JOEH01000010_gene5144	3.848e-86	297.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,2NF0X@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_716806_8	298654.FraEuI1c_2837	2.198e-132	441.0	COG1960@1|root,COG1960@2|Bacteria,2IBE0@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_716806_38	471857.Svir_28590	8.095e-50	193.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158351_k127_716806_25	1229780.BN381_80211	2.171e-92	317.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,3UWN4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158351_k127_716806_54	1121877.JQKF01000001_gene1294	1.765e-23	105.0	COG3255@1|root,COG3255@2|Bacteria,2HGRI@201174|Actinobacteria,4CNUA@84992|Acidimicrobiia	84992|Acidimicrobiia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158351_k127_716806_55	28444.JODQ01000007_gene5144	5.027e-21	106.0	COG0454@1|root,COG0456@2|Bacteria,2HGPE@201174|Actinobacteria,4EHEM@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_716806_27	1313172.YM304_15380	3.814e-87	300.0	COG3394@1|root,COG3394@2|Bacteria,2HG9M@201174|Actinobacteria,4CN7Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRR25158351_k127_716806_16	469383.Cwoe_0785	3.04e-113	374.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158351_k127_716806_43	1283283.ATXA01000008_gene3129	9.737e-41	162.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158351_k127_716806_49	525909.Afer_0756	3.777e-32	131.0	COG0671@1|root,COG0671@2|Bacteria,2HGAE@201174|Actinobacteria,4CN9F@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158351_k127_716806_12	1169154.KB897783_gene4656	1.137e-124	424.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_716806_24	1229780.BN381_80226	9.105e-95	321.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158351_k127_716806_7	1313172.YM304_20970	3.398e-144	467.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_716806_50	1463820.JOGW01000002_gene5849	1.024e-30	127.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	3-HAO,Cupin_2
SRR25158351_k127_716806_30	253839.SSNG_06927	1.985e-79	280.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158351_k127_716806_18	1206744.BAGL01000064_gene4514	6.395e-111	371.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4FYFT@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_716806_52	471852.Tcur_4502	8.631e-26	121.0	COG4319@1|root,COG4319@2|Bacteria,2GNV0@201174|Actinobacteria,4EJGK@85012|Streptosporangiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158351_k127_716806_4	1194972.MVAC_02334	5.546e-161	523.0	COG2141@1|root,COG2141@2|Bacteria,2GITK@201174|Actinobacteria,234AP@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	limB	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158351_k127_716806_22	1313172.YM304_38730	4.185e-101	340.0	2EWQK@1|root,33Q2D@2|Bacteria,2IJ4T@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_716806_19	700508.D174_25040	7.327e-109	365.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,233C1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_716806_37	547163.BN979_03681	1.769e-67	247.0	COG1028@1|root,COG1028@2|Bacteria,2IC24@201174|Actinobacteria,23E0P@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_716806_42	1121933.AUHH01000010_gene2587	4.203e-48	183.0	COG1082@1|root,COG1082@2|Bacteria,2GQ0M@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158351_k127_716806_58	1077972.ARGLB_027_01560	9.283e-06	51.0	COG1359@1|root,COG1359@2|Bacteria,2GUG6@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158351_k127_716806_17	1229780.BN381_310071	2.522e-111	376.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,3UWNK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158351_k127_716806_21	1229780.BN381_310072	2.959e-102	342.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,3UWMR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158351_k127_716806_48	1120934.KB894403_gene398	2.863e-32	133.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	pat	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158351_k127_716806_47	1123023.JIAI01000007_gene1807	8.521e-35	139.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Y_phosphatase3
SRR25158351_k127_716806_9	1160718.SU9_13975	1.043e-131	436.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
SRR25158351_k127_716806_45	1206732.BAGD01000097_gene4123	3.25e-39	151.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,4G0VQ@85025|Nocardiaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR25158351_k127_716806_46	1150864.MILUP08_40624	5.357e-39	167.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_716806_33	671143.DAMO_1527	6.774e-72	264.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158351_k127_716806_20	1380354.JIAN01000005_gene2636	4.13e-106	370.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4F21Z@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158351_k127_716806_26	1869.MB27_27910	8.269e-89	300.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4D92U@85008|Micromonosporales	201174|Actinobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158351_k127_716806_14	28042.GU90_03955	2.053e-114	385.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4DYKS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_716806_15	1306174.JODP01000032_gene4027	9.196e-114	390.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158351_k127_716806_10	1282876.BAOK01000001_gene2087	9.589e-128	427.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria,2U25T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_716806_23	402881.Plav_2454	1.047e-99	355.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	SMP-30 Gluconolaconase	MA20_01275	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158351_k127_716806_3	1229780.BN381_10333	1.025e-161	518.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,3UWNW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158351_k127_716806_13	383372.Rcas_2525	7.151e-118	401.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi,375PJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158351_k127_716806_1	459495.SPLC1_S270380	0.0	1126.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	glsF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158351_k127_716806_53	997346.HMPREF9374_3978	2.052e-25	122.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,27CPE@186824|Thermoactinomycetaceae	91061|Bacilli	L	Staphylococcal nuclease homologues	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158351_k127_716806_5	1123320.KB889686_gene602	8.053e-159	513.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158351_k127_716806_11	1229780.BN381_10320	8.077e-127	439.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,3UW87@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158351_k127_716806_51	656024.FsymDg_2435	1.945e-30	132.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4ET6R@85013|Frankiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158351_k127_716806_41	1048339.KB913029_gene2869	1.192e-48	181.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4EVYI@85013|Frankiales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158351_k127_716806_40	416348.Hlac_2869	5.633e-49	199.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
SRR25158351_k127_716806_35	395495.Lcho_3249	2.581e-68	246.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,2VJR7@28216|Betaproteobacteria,1KNCP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158351_k127_716806_39	1121013.P873_12300	3.262e-49	188.0	arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_716806_31	1313172.YM304_17870	5.262e-75	269.0	COG1085@1|root,COG1085@2|Bacteria,2IJIM@201174|Actinobacteria	201174|Actinobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158351_k127_716806_34	479434.Sthe_0100	2.609e-70	245.0	COG2141@1|root,COG2141@2|Bacteria,2GB6V@200795|Chloroflexi,27XHN@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_717125_5	1313172.YM304_27420	7.481e-175	556.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CMRA@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158351_k127_717125_11	1043205.AFYF01000051_gene3051	2.027e-154	507.0	COG0471@1|root,COG0471@2|Bacteria,2HXIC@201174|Actinobacteria,4FH0P@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
SRR25158351_k127_717125_38	1068978.AMETH_3843	5.502e-71	251.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4DYPT@85010|Pseudonocardiales	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158351_k127_717125_30	351607.Acel_1706	2.971e-97	341.0	COG0770@1|root,COG0770@2|Bacteria,2I2EU@201174|Actinobacteria	201174|Actinobacteria	M	Mur ligase, middle domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158351_k127_717125_42	448385.sce5829	6.34e-61	219.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria,43AS2@68525|delta/epsilon subdivisions,2X666@28221|Deltaproteobacteria,2Z27D@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_717125_41	219305.MCAG_01847	3.779e-62	239.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4D9YN@85008|Micromonosporales	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158351_k127_717125_16	330214.NIDE0407	4.1e-129	436.0	COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,3J11D@40117|Nitrospirae	40117|Nitrospirae	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.1.15,1.8.7.1	ko:K00362,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00530	R00787,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158351_k127_717125_9	298655.KI912267_gene7612	3.562e-163	559.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4ERXH@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158351_k127_717125_13	1206726.BAFV01000030_gene2294	4.201e-150	487.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4FXJN@85025|Nocardiaceae	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158351_k127_717125_57	1206725.BAFU01000203_gene1914	5.309e-22	111.0	COG1544@1|root,COG1544@2|Bacteria,2GPJ5@201174|Actinobacteria,4G331@85025|Nocardiaceae	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
SRR25158351_k127_717125_15	1242864.D187_001075	1.689e-135	459.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,430G4@68525|delta/epsilon subdivisions,2WVMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_717125_53	1229780.BN381_330068	2.193e-27	119.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,3UWYK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158351_k127_717125_14	1229780.BN381_330069	1.295e-142	475.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,3UW9A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158351_k127_717125_61	762963.HMPREF9056_02682	3.965e-08	65.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,4D61T@85005|Actinomycetales	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158351_k127_717125_2	1313172.YM304_15900	8.23e-274	869.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CMS2@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158351_k127_717125_56	1229780.BN381_330071	3.987e-22	100.0	COG1550@1|root,COG1550@2|Bacteria,2I1A0@201174|Actinobacteria,3UXQB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	-	-	-	-	-	-	-	-	-	DUF503
SRR25158351_k127_717125_59	266117.Rxyl_1413	3.522e-16	86.0	COG0858@1|root,COG0858@2|Bacteria,2HPFC@201174|Actinobacteria,4CQTS@84995|Rubrobacteria	84995|Rubrobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158351_k127_717125_34	479432.Sros_2119	6.249e-78	277.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4EHHU@85012|Streptosporangiales	201174|Actinobacteria	S	DHH family	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158351_k127_717125_37	365528.KB891241_gene6185	9.511e-72	252.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4ESDN@85013|Frankiales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158351_k127_717125_32	1313172.YM304_16060	4.303e-91	310.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CN39@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158351_k127_717125_45	1122609.AUGT01000029_gene2619	3.871e-51	199.0	COG2856@1|root,COG2856@2|Bacteria,2GPBB@201174|Actinobacteria,4DTVM@85009|Propionibacteriales	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_717125_52	37659.JNLN01000001_gene2283	8.336e-30	128.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,36KHC@31979|Clostridiaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158351_k127_717125_1	1229780.BN381_330079	1.502e-293	928.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,3UW68@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158351_k127_717125_23	436229.JOEH01000042_gene16	2.105e-119	397.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,2NGPG@228398|Streptacidiphilus	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158351_k127_717125_25	1229780.BN381_330092	1.014e-107	364.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,3UWJR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158351_k127_717125_31	882083.SacmaDRAFT_5686	6.848e-92	310.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DY02@85010|Pseudonocardiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158351_k127_717125_27	103733.JNYO01000003_gene8319	6.867e-102	341.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E1TV@85010|Pseudonocardiales	201174|Actinobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158351_k127_717125_21	1125863.JAFN01000001_gene400	8.854e-122	414.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158351_k127_717125_35	1068978.AMETH_0142	1.311e-75	270.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DZD5@85010|Pseudonocardiales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158351_k127_717125_28	1068978.AMETH_0141	2.45e-101	355.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DYYG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158351_k127_717125_26	1068978.AMETH_0140	9.68e-103	350.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4E14S@85010|Pseudonocardiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_717125_58	1283299.AUKG01000002_gene5121	1.633e-16	85.0	2DS52@1|root,33EJF@2|Bacteria,2H1N9@201174|Actinobacteria,4CST5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_717125_60	1127134.NOCYR_2466	5.617e-14	83.0	COG1309@1|root,COG1309@2|Bacteria,2IH3Q@201174|Actinobacteria,4G8UY@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_717125_10	1229780.BN381_80295	1.648e-156	501.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158351_k127_717125_36	391038.Bphy_2356	8.743e-74	264.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VQ62@28216|Betaproteobacteria,1K2D4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158351_k127_717125_8	665956.HMPREF1032_01445	4.647e-165	535.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158351_k127_717125_43	1298864.AUEQ01000011_gene233	1.902e-60	218.0	COG1028@1|root,COG1028@2|Bacteria,2GKT2@201174|Actinobacteria,237PM@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_717125_3	1313172.YM304_16440	6.904e-198	648.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CMSW@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158351_k127_717125_18	1313172.YM304_16500	4.761e-126	417.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CMWG@84992|Acidimicrobiia	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158351_k127_717125_48	1229780.BN381_80304	2.76e-38	156.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,3UWWX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_717125_17	1469245.JFBG01000054_gene2100	3.278e-128	422.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1T236@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158351_k127_717125_55	1380370.JIBA01000012_gene3850	1.432e-26	117.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria,4FG46@85021|Intrasporangiaceae	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158351_k127_717125_7	1229780.BN381_80311	2.905e-167	534.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,3UW96@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158351_k127_717125_47	414996.IL38_11540	5.267e-41	161.0	COG0730@1|root,COG0730@2|Bacteria,2IIY7@201174|Actinobacteria,407SK@622450|Actinopolysporales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158351_k127_717125_12	1229780.BN381_80317	8.065e-153	505.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,3UW97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158351_k127_717125_39	1437600.JDUI01000002_gene1509	4.622e-70	259.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158351_k127_717125_44	429009.Adeg_1382	4.791e-52	196.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,42F7U@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158351_k127_717125_24	1121877.JQKF01000004_gene1100	1.868e-118	412.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CMWR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158351_k127_717125_29	1313172.YM304_26990	1.289e-97	347.0	COG0436@1|root,COG0436@2|Bacteria,2H440@201174|Actinobacteria,4CMXW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158351_k127_717125_22	1120950.KB892784_gene202	7.274e-121	394.0	COG2171@1|root,COG2171@2|Bacteria,2IBDI@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158351_k127_717125_51	665577.JH993790_gene1074	4.041e-35	141.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158351_k127_717125_40	1313172.YM304_26970	3.26e-67	240.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CN5D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158351_k127_717125_62	351607.Acel_1478	2.691e-05	55.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158351_k127_717125_50	1313172.YM304_26950	2.018e-36	156.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4CN4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158351_k127_717125_0	1229780.BN381_80336	3.475e-313	1009.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,3UWDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158351_k127_717125_49	1127134.NOCYR_0506	3.043e-37	148.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4FX0U@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_717125_20	1229780.BN381_10332	8.418e-123	406.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria,3UW7V@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158351_k127_717125_46	1229780.BN381_10331	2.521e-41	169.0	COG0490@1|root,COG0490@2|Bacteria,2IFBQ@201174|Actinobacteria,3UWTR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158351_k127_717125_6	1123320.KB889696_gene9132	2.297e-167	533.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria	201174|Actinobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158351_k127_717125_4	1137799.GZ78_03045	4.935e-178	577.0	COG0318@1|root,COG0318@2|Bacteria,1MVJ1@1224|Proteobacteria,1RS4E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_717125_33	1448389.BAVQ01000025_gene1257	9.76e-91	308.0	COG1028@1|root,COG1028@2|Bacteria,2HWDM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_717125_19	1229780.BN381_130390	2.6e-123	402.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158351_k127_75548_4	1123320.KB889686_gene725	1.073e-18	90.0	COG0674@1|root,COG0674@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158351_k127_75548_2	1123320.KB889686_gene724	2.039e-101	338.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158351_k127_75548_1	1265310.CCBD010000038_gene2331	6.444e-138	449.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,235W7@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_75548_3	298655.KI912266_gene6515	4.319e-26	122.0	COG5340@1|root,COG5340@2|Bacteria,2I56S@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
SRR25158351_k127_75548_0	656024.FsymDg_2137	2.77e-315	1014.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRR25158351_k127_764900_9	67267.JNXT01000024_gene4491	2.452e-06	55.0	COG0318@1|root,COG0318@2|Bacteria,2IE11@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding
SRR25158351_k127_764900_3	795797.C497_04217	2.012e-63	232.0	COG0059@1|root,arCOG04465@2157|Archaea,2XTGU@28890|Euryarchaeota,23SZC@183963|Halobacteria	2157|Archaea	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158351_k127_764900_6	1229780.BN381_170009	2.245e-38	149.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,3UWZ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Ferric uptake regulator family	catR	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158351_k127_764900_2	1229780.BN381_170008	1.805e-75	256.0	COG1592@1|root,COG1592@2|Bacteria,2IJ63@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158351_k127_764900_4	1229780.BN381_170007	9.997e-54	194.0	COG0247@1|root,COG0247@2|Bacteria,2GVNV@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
SRR25158351_k127_764900_5	1313172.YM304_38230	4.724e-46	170.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CN99@84992|Acidimicrobiia	84992|Acidimicrobiia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158351_k127_764900_1	106370.Francci3_2659	5.272e-97	326.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4ET1B@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_764900_0	1313172.YM304_41020	2.984e-100	335.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_764900_7	1449068.JMLQ01000001_gene255	9.969e-12	71.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4FUV7@85025|Nocardiaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_765806_15	525368.HMPREF0591_3121	7.664e-17	89.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,23435@1762|Mycobacteriaceae	201174|Actinobacteria	EI	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158351_k127_765806_17	1121877.JQKF01000016_gene135	4.851e-10	63.0	2BA7Z@1|root,323N2@2|Bacteria,2HH2A@201174|Actinobacteria,4CP2D@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_765806_11	69042.WH5701_09580	2.453e-62	224.0	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,1GYXA@1129|Synechococcus	1117|Cyanobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158351_k127_765806_10	222534.KB893733_gene5959	6.173e-64	226.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4ESDH@85013|Frankiales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158351_k127_765806_4	1313172.YM304_22610	1.317e-114	383.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CMYU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_765806_5	232348.ADXL01000074_gene13	7.149e-107	365.0	COG0141@1|root,COG0141@2|Bacteria,1G1I2@1117|Cyanobacteria,1GYAR@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158351_k127_765806_9	1451189.CFAL_11075	2.51e-67	235.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,22KIT@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158351_k127_765806_12	469371.Tbis_0451	4.183e-54	201.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4DY2M@85010|Pseudonocardiales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158351_k127_765806_6	1313172.YM304_22570	8.181e-94	327.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CMPY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158351_k127_765806_2	1157490.EL26_03800	4.454e-137	454.0	COG1164@1|root,COG1164@2|Bacteria,1U8XY@1239|Firmicutes,4HEV8@91061|Bacilli	91061|Bacilli	E	Peptidase M3A and M3B thimet oligopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M2,Peptidase_M3
SRR25158351_k127_765806_7	1229780.BN381_330062	1.53e-73	262.0	COG4690@1|root,COG4690@2|Bacteria	2|Bacteria	E	dipeptidase activity	-	-	-	ko:K14358	-	-	-	-	ko00000,ko01002	-	-	-	AAT,Peptidase_C69
SRR25158351_k127_765806_1	994479.GL877881_gene6295	8.181e-165	546.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,4E0V7@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_765806_0	383372.Rcas_2990	5.899e-201	663.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi,374S7@32061|Chloroflexia	32061|Chloroflexia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158351_k127_765806_13	1313172.YM304_19630	1.301e-36	147.0	2BWZ3@1|root,33X4C@2|Bacteria,2H5EF@201174|Actinobacteria,4CN6H@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_765806_18	1236902.ANAS01000024_gene3166	1.558e-07	56.0	COG0526@1|root,COG0526@2|Bacteria,2IR6C@201174|Actinobacteria,4EPZI@85012|Streptosporangiales	201174|Actinobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158351_k127_765806_14	1146883.BLASA_1350	6.779e-23	100.0	COG0526@1|root,COG0526@2|Bacteria,2IR6C@201174|Actinobacteria,4EWWC@85013|Frankiales	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158351_k127_765806_8	709986.Deima_2611	1.197e-71	265.0	COG2326@1|root,COG2326@2|Bacteria,1WKEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158351_k127_765806_3	298655.KI912266_gene6223	3.933e-124	423.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4EX3C@85013|Frankiales	201174|Actinobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_781501_72	342113.DM82_5633	2.607e-23	102.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2W3ZW@28216|Betaproteobacteria,1K91V@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158351_k127_781501_60	1313172.YM304_13340	5.391e-51	190.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158351_k127_781501_33	309799.DICTH_1169	3.708e-107	370.0	COG0008@1|root,COG0008@2|Bacteria	2|Bacteria	J	glutamate-tRNA ligase activity	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158351_k127_781501_22	525909.Afer_1526	8.098e-135	445.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNIG@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_781501_2	1313172.YM304_13020	9.504e-216	687.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CMUV@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158351_k127_781501_24	1313172.YM304_13000	1.415e-130	422.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CMVG@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_781501_18	1313172.YM304_12990	4.498e-144	465.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CMRK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_781501_58	1122611.KB903963_gene4645	3.304e-56	208.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4EQYN@85012|Streptosporangiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_781501_69	525909.Afer_1535	8.176e-27	116.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CN6V@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158351_k127_781501_1	351607.Acel_1591	4.732e-221	701.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4ERE0@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158351_k127_781501_47	326424.FRAAL5828	1.307e-73	252.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4ERFW@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158351_k127_781501_78	1469607.KK073768_gene2710	2.322e-06	53.0	COG1670@1|root,COG1670@2|Bacteria,1GB9Z@1117|Cyanobacteria,1HN7V@1161|Nostocales	1117|Cyanobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.82	ko:K00663,ko:K19301	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_8
SRR25158351_k127_781501_46	1173024.KI912151_gene1587	1.872e-74	258.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_781501_5	525909.Afer_1529	5.534e-201	639.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CNJW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158351_k127_781501_75	1313172.YM304_12740	6.03e-17	87.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,Excalibur,SNase
SRR25158351_k127_781501_68	390989.JOEG01000004_gene3892	4.045e-27	114.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_781501_10	1313172.YM304_12700	1.924e-184	598.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CMQA@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_781501_12	105422.BBPM01000019_gene2652	2.261e-175	559.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,2NHQV@228398|Streptacidiphilus	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_781501_25	1229780.BN381_80340	3.163e-130	428.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158351_k127_781501_50	1313172.YM304_29870	1.439e-66	231.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,4CN48@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158351_k127_781501_71	365528.KB891244_gene6413	2.24e-25	111.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_781501_64	679197.HMPREF9336_02733	6.21e-34	139.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158351_k127_781501_41	1298860.AUEM01000001_gene1390	6.515e-93	314.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_781501_44	1869.MB27_11125	3.661e-82	295.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4DMCW@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_781501_62	649831.L083_5331	2.602e-39	163.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158351_k127_781501_65	1507.HMPREF0262_03240	2.969e-29	126.0	COG0457@1|root,COG1058@1|root,COG1546@1|root,COG4509@1|root,COG0457@2|Bacteria,COG1058@2|Bacteria,COG1546@2|Bacteria,COG4509@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,36ERG@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158351_k127_781501_67	292459.STH2528	3.369e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1VD37@1239|Firmicutes,25BCE@186801|Clostridia	186801|Clostridia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158351_k127_781501_28	44454.NF84_09985	3.318e-121	409.0	COG2124@1|root,COG2124@2|Bacteria,2HSPE@201174|Actinobacteria,2353U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_781501_76	47839.CCAU010000011_gene5648	1.475e-16	93.0	COG1141@1|root,COG1141@2|Bacteria,2GSUD@201174|Actinobacteria,23BGM@1762|Mycobacteriaceae	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SRR25158351_k127_781501_51	1229780.BN381_80314	3.893e-66	243.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,3UXSW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158351_k127_781501_63	2002.JOEQ01000004_gene2536	5.161e-39	164.0	COG2917@1|root,COG2917@2|Bacteria,2IGTQ@201174|Actinobacteria,4EIRE@85012|Streptosporangiales	201174|Actinobacteria	D	probably involved in intracellular septation	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159,IspA
SRR25158351_k127_781501_45	215803.DB30_6391	1.425e-74	261.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,42TE9@68525|delta/epsilon subdivisions,2WPGF@28221|Deltaproteobacteria,2YUH5@29|Myxococcales	28221|Deltaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_781501_20	1229780.BN381_20132	6.382e-136	456.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,3UXHK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158351_k127_781501_3	1185876.BN8_04361	8.969e-215	687.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158351_k127_781501_16	935866.JAER01000019_gene4025	2.381e-160	516.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DPEV@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_781501_43	557599.MKAN_08080	1.079e-84	294.0	COG1414@1|root,COG1414@2|Bacteria,2I3CC@201174|Actinobacteria,2337H@1762|Mycobacteriaceae	201174|Actinobacteria	K	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158351_k127_781501_23	1068978.AMETH_4467	1.717e-132	428.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4E15A@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_781501_34	1394178.AWOO02000116_gene910	3.805e-106	351.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_781501_6	47763.JNZA01000004_gene3847	3.106e-195	614.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA6	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_781501_42	1229780.BN381_350085	1.879e-87	299.0	COG1960@1|root,COG1960@2|Bacteria,2GKUW@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158351_k127_781501_11	469383.Cwoe_2351	2.755e-182	581.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_781501_66	469383.Cwoe_1506	1.45e-28	127.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158351_k127_781501_77	1380391.JIAS01000012_gene4547	1.413e-06	60.0	COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,2JRKR@204441|Rhodospirillales	204441|Rhodospirillales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_781501_29	1449355.JQNR01000005_gene2764	3.538e-121	400.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158351_k127_781501_19	35754.JNYJ01000003_gene6580	1.56e-140	473.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,4DBMF@85008|Micromonosporales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158351_k127_781501_37	66377.JOBH01000008_gene6744	1.076e-98	342.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria	201174|Actinobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
SRR25158351_k127_781501_31	469383.Cwoe_2354	4.86e-116	385.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria	201174|Actinobacteria	I	coenzyme A transferase	cotA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158351_k127_781501_9	561175.KB894093_gene2772	8.098e-187	590.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4EH8Z@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
SRR25158351_k127_781501_61	1150599.MPHLEI_01436	2.87e-40	157.0	COG1545@1|root,COG1545@2|Bacteria,2IFQP@201174|Actinobacteria,238SF@1762|Mycobacteriaceae	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_781501_40	1123320.KB889585_gene1920	2.751e-96	321.0	COG1024@1|root,COG1024@2|Bacteria,2GN54@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA20	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_781501_39	1123320.KB889585_gene1919	1.287e-96	322.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_781501_32	479432.Sros_2090	3.882e-108	377.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_781501_15	1343740.M271_44405	1.718e-163	523.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_781501_56	1298880.AUEV01000012_gene4938	1.48e-61	215.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_781501_30	1313172.YM304_29700	6.758e-121	402.0	COG1232@1|root,COG1232@2|Bacteria,2HG9E@201174|Actinobacteria,4CN7R@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_781501_53	219305.MCAG_05254	1.253e-63	241.0	COG2267@1|root,COG2267@2|Bacteria,2H3BR@201174|Actinobacteria,4DHTZ@85008|Micromonosporales	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_781501_54	929712.KI912613_gene4879	7.531e-63	228.0	COG0412@1|root,COG0412@2|Bacteria,2HG4A@201174|Actinobacteria,4CTKS@84995|Rubrobacteria	84995|Rubrobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158351_k127_781501_48	1123261.AXDW01000013_gene3495	1.462e-70	254.0	COG3752@1|root,COG3752@2|Bacteria,1R4MV@1224|Proteobacteria,1S0DP@1236|Gammaproteobacteria,1X5SX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158351_k127_781501_13	1048339.KB913029_gene4489	1.976e-174	563.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ETYU@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_781501_73	1229780.BN381_780007	2.259e-22	98.0	2CAFG@1|root,32RRB@2|Bacteria,2IQ98@201174|Actinobacteria,3UXT2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
SRR25158351_k127_781501_57	525909.Afer_0719	2.688e-58	216.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,2GKD4@201174|Actinobacteria,4CMR4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
SRR25158351_k127_781501_79	1122221.JHVI01000003_gene331	2.449e-05	54.0	COG2353@1|root,COG2353@2|Bacteria,1WJWX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158351_k127_781501_21	1078020.KEK_22299	1.074e-135	450.0	COG2124@1|root,COG2124@2|Bacteria,2GNJI@201174|Actinobacteria,235VS@1762|Mycobacteriaceae	201174|Actinobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_781501_38	1123320.KB889697_gene9018	1.497e-97	354.0	COG2141@1|root,COG2141@2|Bacteria,2GKPX@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_781501_0	525909.Afer_1346	2.236e-227	720.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CNJF@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158351_k127_781501_49	1220583.GOACH_01_02150	1.233e-68	243.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4GA2X@85026|Gordoniaceae	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_781501_17	1229780.BN381_60006	2.537e-160	518.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,3UXF8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
SRR25158351_k127_781501_27	1380390.JIAT01000011_gene2328	4.995e-122	410.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CS5F@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158351_k127_781501_59	1120936.KB907208_gene1236	4.298e-53	207.0	COG0500@1|root,COG2226@2|Bacteria,2I36Q@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_781501_4	485913.Krac_5846	1.725e-210	674.0	COG0076@1|root,COG0076@2|Bacteria,2G76V@200795|Chloroflexi	200795|Chloroflexi	H	COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158351_k127_781501_36	1440774.Y900_022215	1.117e-101	337.0	COG1234@1|root,COG1234@2|Bacteria,2HV83@201174|Actinobacteria,232BJ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158351_k127_781501_26	1120950.KB892823_gene549	3.856e-128	435.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
SRR25158351_k127_781501_7	298653.Franean1_6853	7.881e-195	622.0	COG3653@1|root,COG3653@2|Bacteria,2IE6H@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_781501_35	1313172.YM304_33260	6.276e-102	342.0	COG1226@1|root,COG3273@1|root,COG1226@2|Bacteria,COG3273@2|Bacteria,2HGEC@201174|Actinobacteria,4CNCJ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158351_k127_781501_14	1386089.N865_16800	5.855e-164	529.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRR25158351_k127_781501_8	1211815.CBYP010000067_gene115	3.545e-187	595.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE1_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_781501_55	649831.L083_5202	5.16e-62	223.0	COG3871@1|root,COG3871@2|Bacteria,2I2S9@201174|Actinobacteria,4DDA5@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_82284_4	1380386.JIAW01000007_gene3930	1.004e-143	464.0	COG2124@1|root,COG2124@2|Bacteria,2GNZS@201174|Actinobacteria,235NS@1762|Mycobacteriaceae	201174|Actinobacteria	C	cytochrome p450	cyp150A5	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_82284_9	298655.KI912266_gene2533	3.789e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,2GW8A@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_82284_3	1380386.JIAW01000010_gene4299	3.203e-169	552.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria,23318@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_82284_13	365528.KB891103_gene3847	1.263e-49	190.0	COG1309@1|root,COG1309@2|Bacteria,2H4XI@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_82284_16	392499.Swit_1729	2.31e-18	92.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2U9J3@28211|Alphaproteobacteria,2K6TF@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_82284_11	1205680.CAKO01000002_gene2546	1.141e-60	224.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_82284_2	436229.JOEH01000009_gene4629	3.109e-175	554.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,2NHZB@228398|Streptacidiphilus	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_82284_12	1160137.KB907307_gene4086	7.445e-58	207.0	COG5517@1|root,COG5517@2|Bacteria,2IG3J@201174|Actinobacteria,4G987@85025|Nocardiaceae	201174|Actinobacteria	Q	SnoaL-like domain	baiE_2	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_82284_18	1380393.JHVP01000004_gene578	7.068e-16	82.0	2DTE3@1|root,33JY8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_82284_10	365528.KB891104_gene3745	5.486e-63	226.0	COG1946@1|root,COG1946@2|Bacteria,2IA8W@201174|Actinobacteria,4ETUA@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158351_k127_82284_6	298655.KI912267_gene7751	8.67e-116	398.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_82284_20	266117.Rxyl_0051	1.258e-12	79.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CPHW@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158351_k127_82284_14	1121937.AUHJ01000002_gene3612	1.716e-29	123.0	COG3467@1|root,COG3467@2|Bacteria,1N17U@1224|Proteobacteria,1SA1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_82284_1	1313172.YM304_03530	2.844e-217	691.0	COG3046@1|root,COG3046@2|Bacteria,2GMF6@201174|Actinobacteria,4CNN7@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
SRR25158351_k127_82284_21	1123322.KB904658_gene1245	7.142e-10	65.0	COG1309@1|root,COG1309@2|Bacteria,2IT26@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_82284_7	1229780.BN381_20046	8.295e-95	316.0	2CG3W@1|root,32X0W@2|Bacteria,2GUB9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_82284_23	869210.Marky_1840	0.0006156	49.0	294HY@1|root,2ZRXK@2|Bacteria,1WK25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158351_k127_82284_15	1386089.N865_05505	1.2e-20	96.0	2EJUD@1|root,33DJ1@2|Bacteria,2I7T2@201174|Actinobacteria	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR25158351_k127_82284_22	1380347.JNII01000006_gene1593	6.841e-08	62.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158351_k127_82284_5	292564.Cyagr_1736	4.977e-135	447.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_82284_0	216594.MMAR_2840	3.395e-320	997.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_82284_8	1121385.AQXW01000004_gene3329	5.247e-81	303.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
SRR25158351_k127_82284_19	1229780.BN381_40049	3.078e-14	85.0	COG1917@1|root,COG1917@2|Bacteria,2H15W@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_82284_24	1122237.AUGQ01000027_gene2290	0.0006171	45.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
SRR25158351_k127_845885_6	1229780.BN381_80154	4.674e-70	254.0	COG2120@1|root,COG2120@2|Bacteria,2IR6Y@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_845885_16	1168059.KB899087_gene2592	7.922e-09	66.0	COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,2UAA7@28211|Alphaproteobacteria,3F1VX@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	Guanylyl transferase CofC like	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158351_k127_845885_12	585531.HMPREF0063_11530	2.519e-35	151.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria,4DMZ0@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158351_k127_845885_5	561175.KB894094_gene1891	1.199e-98	333.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4EHVB@85012|Streptosporangiales	201174|Actinobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158351_k127_845885_1	211114.JOEF01000016_gene3623	8.92e-170	567.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4EAFE@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 38 N-terminal domain	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158351_k127_845885_15	59538.XP_005967836.1	1.354e-27	123.0	COG4359@1|root,2QW23@2759|Eukaryota,38PDP@33154|Opisthokonta	33154|Opisthokonta	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_845885_9	2074.JNYD01000036_gene5374	4.475e-48	183.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,4E123@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_845885_8	1229780.BN381_80160	4.398e-53	205.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,3UWTI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158351_k127_845885_10	1463885.KL578510_gene9590	4.315e-44	171.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158351_k127_845885_17	1313172.YM304_29470	5.068e-05	54.0	2C1D9@1|root,2ZD16@2|Bacteria,2HBJG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_845885_14	134676.ACPL_1738	4.827e-28	123.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4DA6N@85008|Micromonosporales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_845885_3	1048339.KB913029_gene3335	1.51e-123	417.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4ES7K@85013|Frankiales	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158351_k127_845885_4	1122138.AQUZ01000019_gene8179	6.372e-119	413.0	COG2890@1|root,COG2890@2|Bacteria,2I3R2@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158351_k127_845885_2	326424.FRAAL0319	2.294e-130	448.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_845885_0	1313172.YM304_13880	6.698e-179	575.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CNIJ@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158351_k127_845885_11	68170.KL590495_gene8117	9.654e-41	163.0	2DMP1@1|root,32SS8@2|Bacteria,2GSJC@201174|Actinobacteria,4E800@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SRR25158351_k127_845885_7	1122182.KB903837_gene3877	4.726e-62	224.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4DEE0@85008|Micromonosporales	201174|Actinobacteria	O	Redoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158351_k127_846654_6	1265310.CCBD010000061_gene1155	8.723e-81	279.0	2AQ2E@1|root,31F7J@2|Bacteria,2ID84@201174|Actinobacteria,238H3@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_846654_18	1323663.AROI01000026_gene1885	7.997e-17	82.0	2DS3D@1|root,33EC4@2|Bacteria,1P2RI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_846654_13	1313172.YM304_14670	1.36e-29	124.0	2E6FA@1|root,3312Q@2|Bacteria,2GUWJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_846654_0	1123023.JIAI01000019_gene2233	2.714e-190	608.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria,4EASN@85010|Pseudonocardiales	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_846654_2	1449347.JQLN01000005_gene4051	4.789e-144	466.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,2M17S@2063|Kitasatospora	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158351_k127_846654_19	457429.ABJI02000661_gene5038	1.761e-06	53.0	COG2864@1|root,COG2864@2|Bacteria,2GNYK@201174|Actinobacteria	201174|Actinobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158351_k127_846654_4	557599.MKAN_09615	6.457e-114	383.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,235TY@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Diacylglycerol O-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158351_k127_846654_3	530564.Psta_2908	5.224e-123	406.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158351_k127_846654_12	1229780.BN381_90031	5.72e-33	142.0	COG2845@1|root,COG2845@2|Bacteria,2GU62@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
SRR25158351_k127_846654_1	479433.Caci_1300	1.209e-153	499.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria	201174|Actinobacteria	M	Membrane bound O-acyl transferase MBOAT family protein	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
SRR25158351_k127_846654_7	1313172.YM304_11240	2.107e-70	252.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CNYM@84992|Acidimicrobiia	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_846654_14	1157943.KB892705_gene3861	2.382e-28	124.0	COG2968@1|root,COG2968@2|Bacteria,2GM1U@201174|Actinobacteria,235EY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF541)	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158351_k127_846654_15	1323361.JPOC01000060_gene4042	7.807e-28	118.0	2F5RB@1|root,33YA7@2|Bacteria,2GMGC@201174|Actinobacteria,4G0Y7@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,SnoaL_4
SRR25158351_k127_846654_10	1206737.BAGF01000081_gene5192	9.244e-62	228.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4FU6N@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158351_k127_846654_17	1123258.AQXZ01000014_gene4972	3.703e-22	108.0	COG1090@1|root,COG1090@2|Bacteria,2I3Q5@201174|Actinobacteria	201174|Actinobacteria	S	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158351_k127_846654_16	1313172.YM304_26530	9.157e-25	109.0	2DPBC@1|root,331CT@2|Bacteria,2GS2F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_846654_8	1041522.MCOL_V213315	2.477e-67	236.0	COG1117@1|root,COG1117@2|Bacteria,2ID49@201174|Actinobacteria,2384V@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	pstB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158351_k127_846654_5	262316.MAP_0575	6.572e-88	299.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,235M0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Permease component	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158351_k127_846654_9	1120949.KB903317_gene1661	2.344e-64	238.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4DAEM@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158351_k127_846654_11	1408422.JHYF01000001_gene2797	8.022e-41	165.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,36FEY@31979|Clostridiaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158351_k127_873378_3	479435.Kfla_4612	3.342e-114	401.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158351_k127_873378_0	1313172.YM304_18820	1.061e-209	700.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CNQE@84992|Acidimicrobiia	84992|Acidimicrobiia	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
SRR25158351_k127_873378_7	868864.Dester_0215	2.894e-30	130.0	COG0563@1|root,COG0563@2|Bacteria,2G42Z@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
SRR25158351_k127_873378_1	1869.MB27_03825	1.082e-142	465.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4D9MN@85008|Micromonosporales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158351_k127_873378_8	1415166.NONO_c12110	6.509e-08	60.0	29WEA@1|root,30I02@2|Bacteria,2INKF@201174|Actinobacteria,4FY98@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_873378_5	298653.Franean1_2324	4.329e-59	208.0	COG0655@1|root,COG0655@2|Bacteria,2II43@201174|Actinobacteria,4ESWD@85013|Frankiales	201174|Actinobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158351_k127_873378_6	861299.J421_2420	1.466e-52	204.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158351_k127_873378_2	1173025.GEI7407_2503	1.441e-117	413.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS_3,PAS_9
SRR25158351_k127_873378_4	68170.KL590525_gene3020	4.581e-108	356.0	COG0304@1|root,COG0304@2|Bacteria,2IAET@201174|Actinobacteria,4E090@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_922919_0	251221.35211629	5.921e-37	150.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria	1117|Cyanobacteria	KT	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_922919_2	102129.Lepto7375DRAFT_6622	1.2e-13	83.0	COG0317@1|root,COG0317@2|Bacteria,1GEK3@1117|Cyanobacteria	1117|Cyanobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158351_k127_922919_1	1173028.ANKO01000250_gene2411	6.429e-30	136.0	COG1216@1|root,COG1216@2|Bacteria,1G8NN@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_922919_3	944547.ABLL_0168	2.767e-05	51.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2YQ19@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158351_k127_932977_34	465541.ATCJ01000005_gene3574	9.942e-05	49.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158351_k127_932977_11	640132.Srot_1276	1.931e-96	326.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158351_k127_932977_23	1123320.KB889719_gene7431	7.168e-38	158.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158351_k127_932977_16	1229780.BN381_10186	5.323e-76	276.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,3UXCJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158351_k127_932977_12	1382306.JNIM01000001_gene1897	1.202e-92	313.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158351_k127_932977_4	1229780.BN381_10192	1.566e-131	465.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,3UWUN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158351_k127_932977_24	1313172.YM304_28540	4.141e-31	137.0	COG0526@1|root,COG0526@2|Bacteria,2H7FG@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_932977_2	525909.Afer_1606	1.441e-227	736.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158351_k127_932977_29	666685.R2APBS1_1150	1.364e-12	78.0	COG1266@1|root,COG1266@2|Bacteria,1NID0@1224|Proteobacteria,1SUC2@1236|Gammaproteobacteria,1X6ZA@135614|Xanthomonadales	135614|Xanthomonadales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158351_k127_932977_7	1313172.YM304_28500	8.645e-116	404.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_932977_3	1229780.BN381_10200	2.742e-170	546.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,3UWAW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_932977_26	1229780.BN381_10201	9.14e-25	114.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158351_k127_932977_14	1229780.BN381_10202	3.75e-80	281.0	COG2222@1|root,COG2222@2|Bacteria,2HGM1@201174|Actinobacteria,3UXD9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS,bact-PGI_C
SRR25158351_k127_932977_31	1123024.AUII01000040_gene1360	2.266e-07	64.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E32T@85010|Pseudonocardiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
SRR25158351_k127_932977_1	1210045.ALNP01000021_gene520	7.749e-246	767.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158351_k127_932977_25	1313172.YM304_28380	2.71e-28	123.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	comF	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pribosyltran
SRR25158351_k127_932977_30	1122138.AQUZ01000082_gene3845	9.462e-08	59.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4DQCT@85009|Propionibacteriales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158351_k127_932977_27	1449346.JQMO01000003_gene5623	3.405e-20	105.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria,2M2QI@2063|Kitasatospora	201174|Actinobacteria	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158351_k127_932977_0	1229780.BN381_80106	0.0	1090.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,3UW8Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158351_k127_932977_6	525909.Afer_1762	5.244e-122	409.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CMPD@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_932977_8	1229780.BN381_80108	2.196e-104	344.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,3UW73@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158351_k127_932977_19	1121877.JQKF01000008_gene673	4.818e-50	189.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CN4Q@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
SRR25158351_k127_932977_21	1229172.JQFA01000002_gene4647	4.497e-43	173.0	COG4942@1|root,COG4942@2|Bacteria,1G2JU@1117|Cyanobacteria,1H7G0@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158351_k127_932977_10	1122135.KB893166_gene2898	1.227e-98	326.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Peroxiredoxin	MA20_35715	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158351_k127_932977_32	1121019.AUMN01000001_gene465	3.236e-07	61.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,1W7N5@1268|Micrococcaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
SRR25158351_k127_932977_28	1380393.JHVP01000012_gene2834	3.869e-20	98.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,4ERNW@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	entS_1	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158351_k127_932977_22	1206741.BAFX01000113_gene7290	5.979e-38	147.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria,4G2S5@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158351_k127_932977_18	1229780.BN381_40079	2.093e-65	235.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,3UWQB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158351_k127_932977_20	1122611.KB903949_gene6556	1.496e-43	168.0	COG3550@1|root,COG3550@2|Bacteria,2GJ1X@201174|Actinobacteria,4EJXI@85012|Streptosporangiales	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158351_k127_932977_5	446468.Ndas_3287	8.452e-126	411.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4EGV0@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_932977_15	1229780.BN381_80217	6.545e-77	265.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158351_k127_932977_17	1313172.YM304_09930	1.853e-68	250.0	28TMF@1|root,2ZFV1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_932977_13	1229780.BN381_60076	6.134e-83	304.0	COG2321@1|root,COG2321@2|Bacteria,2HBKZ@201174|Actinobacteria	201174|Actinobacteria	S	neutral zinc metallopeptidase	lpqM	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158351_k127_932977_9	1394178.AWOO02000049_gene6151	3.975e-99	328.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EFUR@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_94466_40	525909.Afer_1918	1.269e-76	261.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_94466_78	525909.Afer_1917	1.84e-14	76.0	29XP9@1|root,30JEV@2|Bacteria,2HGER@201174|Actinobacteria,4CNCS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158351_k127_94466_26	1229780.BN381_110020	3.029e-95	327.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,3UXC9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158351_k127_94466_51	1313172.YM304_37680	7.728e-55	205.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CN76@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158351_k127_94466_47	525909.Afer_1913	1.114e-63	224.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CNRA@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158351_k127_94466_39	1229780.BN381_110024	1.055e-77	273.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,3UWJV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158351_k127_94466_42	644282.Deba_0763	3.771e-74	259.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158351_k127_94466_59	1229780.BN381_110026	3.305e-42	162.0	2F3QB@1|root,33WH4@2|Bacteria,2H50W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_94466_72	1229780.BN381_110027	3.211e-24	106.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,3UWX7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158351_k127_94466_65	269800.Tfu_2890	3.19e-35	147.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4EJQJ@85012|Streptosporangiales	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158351_k127_94466_62	1229780.BN381_110029	1.472e-36	150.0	COG5495@1|root,COG5495@2|Bacteria,2HGVN@201174|Actinobacteria,3UXIN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520
SRR25158351_k127_94466_32	469383.Cwoe_2891	4.218e-88	306.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4CPNC@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158351_k127_94466_9	1121272.KB903261_gene6474	1.694e-134	445.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4D9BT@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158351_k127_94466_28	1229780.BN381_110032	1.498e-92	314.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,3UWIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158351_k127_94466_25	500153.JOEK01000001_gene3516	9.986e-96	320.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158351_k127_94466_2	1313172.YM304_28830	1.229e-190	620.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CMX2@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_94466_38	1313172.YM304_37740	2.528e-80	279.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158351_k127_94466_79	585531.HMPREF0063_11577	8.12e-14	83.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,4DNTT@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158351_k127_94466_48	1313172.YM304_37760	1.732e-61	224.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158351_k127_94466_33	1313172.YM304_03920	1.722e-87	299.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CMZ7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158351_k127_94466_0	1121272.KB903261_gene6480	0.0	1241.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4D8QE@85008|Micromonosporales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158351_k127_94466_63	1382306.JNIM01000001_gene621	2.677e-36	151.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_94466_54	285514.JNWO01000008_gene2846	1.225e-51	208.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase_like
SRR25158351_k127_94466_10	211114.JOEF01000003_gene3241	7.552e-130	436.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DZGZ@85010|Pseudonocardiales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158351_k127_94466_16	298654.FraEuI1c_0376	2.802e-109	369.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4ERXA@85013|Frankiales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158351_k127_94466_61	1229780.BN381_150083	2.547e-37	150.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158351_k127_94466_50	1229780.BN381_150086	2.048e-57	210.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,3UWRE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420,ko:K10914,ko:K21561,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158351_k127_94466_45	1121877.JQKF01000035_gene1966	3.313e-67	239.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CN2D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158351_k127_94466_58	1313172.YM304_04650	2.056e-47	181.0	COG1211@1|root,COG1211@2|Bacteria,2I767@201174|Actinobacteria	201174|Actinobacteria	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158351_k127_94466_64	1089553.Tph_c03860	5.601e-36	151.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,42FTZ@68295|Thermoanaerobacterales	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158351_k127_94466_12	1313172.YM304_34860	5.739e-122	406.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CMTW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158351_k127_94466_55	1229780.BN381_150089	1.16e-49	200.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,3UWDZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158351_k127_94466_76	1111131.HMPREF1255_0928	1.229e-15	81.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158351_k127_94466_24	1896.JOAU01000038_gene2252	1.76e-97	338.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria	201174|Actinobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158351_k127_94466_11	215803.DB30_6316	1.741e-129	427.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2YWVW@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158351_k127_94466_41	1380347.JNII01000007_gene76	1.672e-75	267.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158351_k127_94466_31	36809.MAB_3073	2.468e-88	295.0	COG2128@1|root,COG2128@2|Bacteria,2IAD2@201174|Actinobacteria,23864@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_94466_37	1380356.JNIK01000002_gene4729	1.225e-81	281.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4ES7J@85013|Frankiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158351_k127_94466_6	525909.Afer_1848	5.862e-158	511.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria	201174|Actinobacteria	E	Threonine synthase	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_94466_68	1229780.BN381_150094	2.356e-31	125.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,3UXHU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_94466_52	1463825.JNXC01000002_gene4487	2.9e-52	192.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4DXCH@85010|Pseudonocardiales	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158351_k127_94466_21	266117.Rxyl_1173	1.065e-102	349.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158351_k127_94466_34	266117.Rxyl_1175	9.782e-87	298.0	COG1840@1|root,COG1840@2|Bacteria,2HRRI@201174|Actinobacteria,4CTU6@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158351_k127_94466_15	1313172.YM304_15180	2.79e-110	376.0	COG1178@1|root,COG1178@2|Bacteria,2HFVM@201174|Actinobacteria,4CP3M@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158351_k127_94466_1	397278.JOJN01000006_gene1044	1.802e-247	776.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNNQ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_94466_46	497964.CfE428DRAFT_2423	8.307e-65	230.0	COG3253@1|root,COG3253@2|Bacteria,46SQD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Chlorite dismutase	ywfI	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158351_k127_94466_7	1089545.KB913037_gene6411	2.108e-150	486.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DX4Q@85010|Pseudonocardiales	201174|Actinobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158351_k127_94466_56	452652.KSE_23320	3.886e-49	180.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,2M3NY@2063|Kitasatospora	201174|Actinobacteria	K	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158351_k127_94466_8	66429.JOFL01000030_gene5180	3.467e-135	463.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158351_k127_94466_35	1313172.YM304_05030	5.102e-84	284.0	COG1051@1|root,COG1051@2|Bacteria,2HG6C@201174|Actinobacteria,4CN3B@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
SRR25158351_k127_94466_44	1463821.JOGR01000007_gene253	1.108e-68	239.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4EZ1P@85014|Glycomycetales	201174|Actinobacteria	F	Phosphoribosyl transferase domain	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158351_k127_94466_17	44454.NF84_01055	4.542e-109	377.0	COG1960@1|root,COG1960@2|Bacteria,2IAIE@201174|Actinobacteria,237ZZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE35	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158351_k127_94466_81	589873.EP13_10260	1.813e-07	63.0	COG4932@1|root,COG4932@2|Bacteria,1P7ZM@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_94466_14	469383.Cwoe_3478	2.426e-112	379.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158351_k127_94466_27	1209984.BN978_00894	1.668e-94	328.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,238BI@1762|Mycobacteriaceae	201174|Actinobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158351_k127_94466_30	1313172.YM304_41440	5.576e-90	311.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CNYR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_94466_5	1123024.AUII01000021_gene69	1.098e-172	559.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158351_k127_94466_84	797304.Natgr_3017	0.0004192	53.0	arCOG02898@1|root,arCOG02898@2157|Archaea,2XZ0V@28890|Euryarchaeota,23WT3@183963|Halobacteria	183963|Halobacteria	S	Polyketide cyclase / dehydrase and lipid transport	blp	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_94466_43	1283299.AUKG01000001_gene1973	1.189e-72	254.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158351_k127_94466_13	326424.FRAAL0382	4.89e-115	383.0	COG1804@1|root,COG1804@2|Bacteria,2H3YW@201174|Actinobacteria	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_94466_29	1229780.BN381_30008	1.924e-90	320.0	COG0038@1|root,COG0038@2|Bacteria	2|Bacteria	P	chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158351_k127_94466_22	1944.JOAZ01000023_gene2555	1.825e-99	332.0	COG1131@1|root,COG1131@2|Bacteria,2IE14@201174|Actinobacteria	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158351_k127_94466_36	1463936.JOJI01000001_gene1858	1.185e-81	282.0	COG0842@1|root,COG0842@2|Bacteria,2I9MM@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158351_k127_94466_69	929712.KI912613_gene1017	5.016e-29	124.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4CQHQ@84995|Rubrobacteria	84995|Rubrobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158351_k127_94466_71	479433.Caci_7364	7.858e-25	108.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158351_k127_94466_75	318424.EU78_27995	4.022e-21	103.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,2396M@1762|Mycobacteriaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB2	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158351_k127_94466_20	2002.JOEQ01000009_gene6526	2.973e-107	359.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4EFWM@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	fadE36	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_94466_70	264198.Reut_C6254	1.971e-26	120.0	COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2VKNP@28216|Betaproteobacteria,1K3W7@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158351_k127_94466_77	1122611.KB903950_gene6423	1.499e-15	89.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158351_k127_94466_57	1352941.M877_30665	5.952e-49	195.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158351_k127_94466_73	696369.KI912183_gene1030	8.226e-24	115.0	COG0392@1|root,COG0392@2|Bacteria,1VDGK@1239|Firmicutes,24Q29@186801|Clostridia,262MZ@186807|Peptococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158351_k127_94466_49	1229780.BN381_410039	2.176e-58	213.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,3UXF2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158351_k127_94466_3	1464048.JNZS01000008_gene6079	4.361e-177	572.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DA3Q@85008|Micromonosporales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_94466_60	1121272.KB903252_gene947	5.842e-38	145.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria,4DE8F@85008|Micromonosporales	201174|Actinobacteria	S	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_94466_4	1229780.BN381_90073	1.288e-176	565.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158351_k127_94466_19	1313172.YM304_10900	2.499e-108	366.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158351_k127_94466_67	469383.Cwoe_1828	7.919e-32	133.0	COG1011@1|root,COG1011@2|Bacteria,2HP8B@201174|Actinobacteria,4CTW5@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158351_k127_94466_53	877455.Metbo_0099	6.841e-52	193.0	COG1968@1|root,arCOG04761@2157|Archaea,2XTYX@28890|Euryarchaeota,23NY7@183925|Methanobacteria	183925|Methanobacteria	I	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158351_k127_94466_82	429009.Adeg_1039	7.962e-07	60.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,42H14@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158351_k127_94466_80	653045.Strvi_1097	4.925e-11	74.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158351_k127_94466_66	1313172.YM304_35160	7.572e-33	142.0	COG0344@1|root,COG0344@2|Bacteria,2IF8Y@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158351_k127_94466_18	1229780.BN381_90066	1e-108	370.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria,3UWE1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158351_k127_94466_23	525909.Afer_0486	2.507e-99	346.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CMP8@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158351_k127_994854_18	1089549.AZUQ01000001_gene1682	4.255e-10	71.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4EY90@85014|Glycomycetales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_994854_5	710111.FraQA3DRAFT_4085	1.003e-92	317.0	COG1804@1|root,COG1804@2|Bacteria	2|Bacteria	C	formyl-CoA transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_994854_1	298655.KI912266_gene5581	1.65e-162	531.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_994854_12	1385518.N798_10725	6.996e-47	174.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,4FGZW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_994854_19	367299.JOEE01000001_gene1590	8.402e-08	61.0	2B9Q9@1|root,3232U@2|Bacteria,2H7MN@201174|Actinobacteria,4FJGB@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_994854_8	1121943.KB899993_gene235	3.916e-65	237.0	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,1RNIQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495	Trehalose_PPase
SRR25158351_k127_994854_7	1968.JOEV01000013_gene868	2.666e-69	247.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria	201174|Actinobacteria	H	Pfam UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158351_k127_994854_10	1122611.KB904007_gene7764	7.417e-61	219.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_994854_4	1123322.KB904635_gene2587	1.74e-110	366.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_994854_11	710111.FraQA3DRAFT_2786	1.897e-51	197.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4ESJ2@85013|Frankiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158351_k127_994854_6	1121937.AUHJ01000008_gene1962	2.116e-89	311.0	COG2141@1|root,COG2141@2|Bacteria,1NXIH@1224|Proteobacteria,1SZ1M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_994854_14	392499.Swit_1946	6.389e-31	128.0	29ANX@1|root,2ZXNT@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158351_k127_994854_16	390235.PputW619_1676	1.228e-24	112.0	COG4454@1|root,COG4454@2|Bacteria,1N7A1@1224|Proteobacteria	1224|Proteobacteria	P	Copper-binding protein	cusF	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158351_k127_994854_0	298654.FraEuI1c_3304	1.146e-166	558.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_994854_13	1313172.YM304_33750	1.195e-42	169.0	28MAM@1|root,2Z85E@2|Bacteria,2I85U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_994854_2	557599.MKAN_07995	2.174e-162	522.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria,236FJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	alcohol dehydrogenase	adh	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_994854_9	557599.MKAN_27550	3.698e-64	229.0	COG2128@1|root,COG2128@2|Bacteria,2IAC5@201174|Actinobacteria,236CM@1762|Mycobacteriaceae	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_994854_3	1122609.AUGT01000010_gene3664	2.515e-129	434.0	COG3000@1|root,COG3000@2|Bacteria,2GMF0@201174|Actinobacteria,4DMY3@85009|Propionibacteriales	201174|Actinobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158351_k127_994854_21	2002.JOEQ01000023_gene1280	7.935e-07	58.0	COG1432@1|root,COG1432@2|Bacteria,2GUD1@201174|Actinobacteria	201174|Actinobacteria	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158351_k127_994854_15	222534.KB893717_gene2176	5.592e-26	122.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
SRR25158351_k127_994854_20	1121272.KB903292_gene3948	2.62e-07	64.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
## 2903 queries scanned
## Total time (seconds): 27.734593868255615
## Rate: 104.67 q/s