## Sun Dec 14 17:00:11 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158351_bin.2.fa -m mmseqs --itype genome -o SRR25158351_bin.2 --output_dir /data/result/bins/wyx/egg/SRR25158351_bin.2 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158351_k127_1009452_1	1206729.BAFZ01000128_gene2114	1.275e-24	119.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4FUQC@85025|Nocardiaceae	201174|Actinobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158351_k127_1009452_0	292459.STH230	0.0	1431.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158351_k127_1031726_24	1297742.A176_06944	5.855e-18	85.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42UPV@68525|delta/epsilon subdivisions,2WQB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158351_k127_1031726_12	671143.DAMO_1605	1.825e-64	228.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158351_k127_1031726_15	1379698.RBG1_1C00001G1052	1.305e-35	148.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SRR25158351_k127_1031726_1	929712.KI912613_gene2430	5.497e-157	508.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CP64@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158351_k127_1031726_19	1051632.TPY_0861	5.138e-25	115.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,3WDH5@538999|Clostridiales incertae sedis	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158351_k127_1031726_3	1379698.RBG1_1C00001G1055	1.409e-138	458.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158351_k127_1031726_2	469383.Cwoe_1155	3.885e-144	487.0	COG1034@1|root,COG1153@1|root,COG1034@2|Bacteria,COG1153@2|Bacteria,2GJGX@201174|Actinobacteria,4CR3F@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158351_k127_1031726_6	671143.DAMO_2695	4.01e-108	361.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158351_k127_1031726_14	926569.ANT_08370	1.638e-46	172.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158351_k127_1031726_26	1232410.KI421424_gene1790	3.607e-12	74.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42V5H@68525|delta/epsilon subdivisions,2WQF4@28221|Deltaproteobacteria,43USM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ-1	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158351_k127_1031726_18	469383.Cwoe_1159	1.979e-26	111.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CQIE@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158351_k127_1031726_4	671143.DAMO_2692	1.111e-136	457.0	COG1009@1|root,COG1009@2|Bacteria,2NNU6@2323|unclassified Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00341,ko:K12137	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945	Proton_antipo_M,Proton_antipo_N
SRR25158351_k127_1031726_8	671143.DAMO_2691	3.143e-100	347.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158351_k127_1031726_7	469383.Cwoe_1162	4.159e-108	366.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_1031726_25	1283299.AUKG01000001_gene1967	2.165e-17	91.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158351_k127_1031726_22	1122939.ATUD01000026_gene2811	3.207e-21	100.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158351_k127_1031726_13	1128421.JAGA01000002_gene621	3.426e-47	181.0	COG1877@1|root,COG1877@2|Bacteria,2NPXY@2323|unclassified Bacteria	2|Bacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158351_k127_1031726_5	357808.RoseRS_0076	1.351e-118	401.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi,376BY@32061|Chloroflexia	32061|Chloroflexia	L	Helix-hairpin-helix DNA-binding, class 1	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158351_k127_1031726_20	1122939.ATUD01000004_gene3816	2.643e-23	115.0	COG1376@1|root,COG1376@2|Bacteria,2HPTN@201174|Actinobacteria,4CR7H@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158351_k127_1031726_16	459495.SPLC1_S550600	8.832e-30	123.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1HBSI@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158351_k127_1031726_0	1380390.JIAT01000009_gene1982	0.0	1086.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158351_k127_1031726_21	59538.XP_005973450.1	2.112e-22	109.0	COG4359@1|root,2QRU0@2759|Eukaryota,39PCC@33154|Opisthokonta	33154|Opisthokonta	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_1031726_17	298653.Franean1_0351	3.218e-27	126.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria,4EW7R@85013|Frankiales	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158351_k127_1031726_29	1386089.N865_18955	2.802e-05	56.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4FFYF@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_1031726_23	469383.Cwoe_3189	4.144e-20	106.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CR9C@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158351_k127_1031726_28	351607.Acel_0141	2.57e-06	50.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4EVPW@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158351_k127_1031726_10	266117.Rxyl_1220	1.952e-72	247.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria	201174|Actinobacteria	V	Intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158351_k127_1031726_9	1489678.RDMS_04430	4.699e-83	297.0	COG0825@1|root,COG0825@2|Bacteria,1WJ82@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158351_k127_1031726_11	195105.CN97_13000	2.385e-72	256.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158351_k127_1031726_27	7668.SPU_016406-tr	6.494e-07	56.0	COG2453@1|root,KOG1716@2759|Eukaryota,396CM@33154|Opisthokonta,3BIW3@33208|Metazoa,3CWTY@33213|Bilateria	33208|Metazoa	V	MAP kinase phosphatase activity	DUSP3	GO:0000188,GO:0001701,GO:0001772,GO:0001932,GO:0001933,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007162,GO:0007275,GO:0007346,GO:0008138,GO:0008150,GO:0008152,GO:0009790,GO:0009792,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022408,GO:0023051,GO:0023057,GO:0030155,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032872,GO:0032873,GO:0033549,GO:0033673,GO:0035335,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043009,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043412,GO:0043549,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045787,GO:0045859,GO:0045931,GO:0045936,GO:0046328,GO:0046329,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048856,GO:0050776,GO:0050789,GO:0050790,GO:0050794,GO:0050854,GO:0050856,GO:0050858,GO:0050860,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051249,GO:0051250,GO:0051338,GO:0051348,GO:0051726,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0070302,GO:0070303,GO:0070372,GO:0070373,GO:0071704,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0140096,GO:1901564,GO:1902531,GO:1902532,GO:1903037,GO:1903038	3.1.3.16,3.1.3.48	ko:K14165,ko:K17614	ko04010,map04010	-	-	-	ko00000,ko00001,ko01000,ko01009	-	-	-	DSPc
SRR25158351_k127_104080_17	266117.Rxyl_0142	1.114e-45	169.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4CQIW@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158351_k127_104080_7	1144310.PMI07_004697	9.549e-105	346.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,4BAH6@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_104080_8	469383.Cwoe_4727	6.072e-103	350.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CRSZ@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158351_k127_104080_11	1074488.AGBX01000001_gene273	6.967e-82	286.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4FBD8@85020|Dermabacteraceae	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158351_k127_104080_20	1121362.A605_11485	2.644e-23	113.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria	201174|Actinobacteria	CH	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158351_k127_104080_23	58123.JOFJ01000024_gene3466	6.524e-10	67.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4EK5Q@85012|Streptosporangiales	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158351_k127_104080_24	253839.SSNG_04559	8.116e-09	62.0	COG2329@1|root,COG2329@2|Bacteria,2ISIW@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158351_k127_104080_10	644966.Tmar_2037	4.565e-82	286.0	COG0446@1|root,COG0446@2|Bacteria,1UC47@1239|Firmicutes,24NN7@186801|Clostridia	186801|Clostridia	S	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_104080_19	1033802.SSPSH_003236	6.032e-34	144.0	COG0500@1|root,COG2226@2|Bacteria,1PN45@1224|Proteobacteria,1RP4K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	yafE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_104080_15	1283299.AUKG01000002_gene4226	4.261e-60	220.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CQ0G@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_104080_16	1449347.JQLN01000004_gene6480	8.805e-59	210.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria,2M3WY@2063|Kitasatospora	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158351_k127_104080_0	1172186.KB911464_gene4856	0.0	1037.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158351_k127_104080_9	350058.Mvan_1594	1.863e-99	367.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,235IH@1762|Mycobacteriaceae	201174|Actinobacteria	I	synthetase	fadD11_1	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158351_k127_104080_14	1095767.CAHD01000035_gene1168	3.64e-64	235.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4F0JA@85016|Cellulomonadaceae	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158351_k127_104080_12	420324.KI912045_gene4360	8.958e-77	266.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,1JSFG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158351_k127_104080_4	266117.Rxyl_2061	3.915e-137	449.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP66@84995|Rubrobacteria	201174|Actinobacteria	C	PFAM acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_104080_25	1541065.JRFE01000029_gene3512	0.0001721	52.0	COG0346@1|root,COG0599@1|root,COG3631@1|root,COG0346@2|Bacteria,COG0599@2|Bacteria,COG3631@2|Bacteria,1GNQ2@1117|Cyanobacteria,3VM2Z@52604|Pleurocapsales	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EthD,Glyoxalase
SRR25158351_k127_104080_18	1122622.ATWJ01000012_gene1055	9.212e-40	156.0	COG0684@1|root,COG0684@2|Bacteria,2IH5H@201174|Actinobacteria	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158351_k127_104080_2	42256.RradSPS_0715	5.576e-191	620.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,2IG04@201174|Actinobacteria,4CPK0@84995|Rubrobacteria	84995|Rubrobacteria	CK	DHHA2	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
SRR25158351_k127_104080_21	1123368.AUIS01000004_gene280	3.726e-20	101.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Mechanosensitive Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158351_k127_104080_6	344747.PM8797T_10474	6.534e-109	366.0	COG0523@1|root,COG0523@2|Bacteria,2IXBH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
SRR25158351_k127_104080_1	344747.PM8797T_10469	1.931e-213	670.0	COG1234@1|root,COG1234@2|Bacteria,2J27A@203682|Planctomycetes	203682|Planctomycetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_104080_13	525897.Dbac_1094	3.316e-71	257.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	beta-lactamase domain protein	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158351_k127_104080_22	1123024.AUII01000002_gene1199	4.201e-11	71.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4DXE9@85010|Pseudonocardiales	201174|Actinobacteria	K	lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158351_k127_104080_3	344747.PM8797T_10469	2.027e-174	557.0	COG1234@1|root,COG1234@2|Bacteria,2J27A@203682|Planctomycetes	203682|Planctomycetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_104080_5	1121366.KB892469_gene1736	2.717e-126	429.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,22N4Z@1653|Corynebacteriaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_1053213_0	314285.KT71_03337	6.629e-85	291.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RW40@1236|Gammaproteobacteria,1J8F4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158351_k127_1053213_1	118166.JH976537_gene2287	3.468e-35	141.0	COG3011@1|root,COG3011@2|Bacteria,1G5AK@1117|Cyanobacteria,1HB8X@1150|Oscillatoriales	1117|Cyanobacteria	S	thiol-disulphide oxidoreductase DCC	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158351_k127_1053213_2	1121937.AUHJ01000002_gene3612	5.787e-35	140.0	COG3467@1|root,COG3467@2|Bacteria,1N17U@1224|Proteobacteria,1SA1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_1053213_3	1340493.JNIF01000004_gene1115	7.32e-26	114.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	ycgE	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158351_k127_1053994_3	1380390.JIAT01000010_gene3596	1.51e-23	113.0	COG0598@1|root,COG0598@2|Bacteria,2HPVI@201174|Actinobacteria,4CRZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
SRR25158351_k127_1053994_6	765420.OSCT_2025	1.928e-11	71.0	28HBW@1|root,2Z7NV@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1998
SRR25158351_k127_1053994_0	765420.OSCT_2024	4.452e-63	227.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158351_k127_1053994_5	1229780.BN381_800001	2.72e-15	81.0	COG0610@1|root,COG2865@1|root,COG0610@2|Bacteria,COG2865@2|Bacteria,2HI69@201174|Actinobacteria,3UX99@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
SRR25158351_k127_1053994_2	317655.Sala_2789	1.779e-34	142.0	COG1309@1|root,COG1309@2|Bacteria,1RAHE@1224|Proteobacteria,2U866@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1053994_4	471854.Dfer_1923	1.787e-22	103.0	COG0662@1|root,COG0662@2|Bacteria,4NPR6@976|Bacteroidetes,47T63@768503|Cytophagia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_1053994_1	479434.Sthe_0073	7.877e-36	145.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158351_k127_1053994_7	981384.AEYW01000001_gene1490	1.566e-09	64.0	COG1234@1|root,COG1234@2|Bacteria,1RIJP@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_4
SRR25158351_k127_1054187_1	1121272.KB903259_gene6524	1.081e-50	188.0	COG3247@1|root,COG3247@2|Bacteria,2ISIY@201174|Actinobacteria,4DMAA@85008|Micromonosporales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158351_k127_1054187_0	373994.Riv7116_5818	5.76e-262	825.0	COG1554@1|root,COG1554@2|Bacteria,1G0DN@1117|Cyanobacteria,1HIEI@1161|Nostocales	1117|Cyanobacteria	G	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158351_k127_1056730_0	266940.Krad_3975	8.446e-72	253.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1056730_2	479434.Sthe_1082	5.741e-37	154.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158351_k127_1056730_1	266940.Krad_3977	3.175e-71	252.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria	201174|Actinobacteria	V	abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1068064_3	439481.Aboo_0339	6.214e-79	279.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,3F2FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
SRR25158351_k127_1068064_11	693661.Arcve_2048	9.106e-11	72.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,246C7@183980|Archaeoglobi	183980|Archaeoglobi	V	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158351_k127_1068064_5	335543.Sfum_2312	9.962e-74	259.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,42RTY@68525|delta/epsilon subdivisions,2WNFS@28221|Deltaproteobacteria,2MRVF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1,3.5.5.7	ko:K01501,ko:K01502	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05358,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC01336,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_1068064_8	388413.ALPR1_16993	1.196e-42	166.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,47NTC@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_1068064_9	693661.Arcve_2084	1.203e-34	142.0	COG0846@1|root,arCOG04248@2157|Archaea,2XT4V@28890|Euryarchaeota,246N6@183980|Archaeoglobi	183980|Archaeoglobi	F	NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158351_k127_1068064_12	469383.Cwoe_2844	3.614e-08	64.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158351_k127_1068064_4	1121468.AUBR01000043_gene1756	2.04e-74	267.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158351_k127_1068064_13	755178.Cyan10605_2705	2.868e-05	47.0	COG1376@1|root,COG1376@2|Bacteria,1G74K@1117|Cyanobacteria	1117|Cyanobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158351_k127_1068064_2	575540.Isop_2885	2.649e-79	284.0	COG1012@1|root,COG1012@2|Bacteria,2IYF7@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.21,1.2.1.22,1.2.1.79	ko:K00135,ko:K07248	ko00250,ko00310,ko00350,ko00620,ko00630,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00620,map00630,map00650,map00760,map01100,map01120	M00027	R00203,R00713,R00714,R01333,R01446,R02401	RC00080,RC00104,RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1068064_6	1283299.AUKG01000003_gene220	1.254e-55	199.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CQGA@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158351_k127_1068064_7	1434929.X946_137	4.727e-43	167.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VQAT@28216|Betaproteobacteria,1K4PQ@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_1068064_0	272558.10176423	9.776e-110	366.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_1068064_10	571166.KI421510_gene211	3.617e-28	122.0	COG2030@1|root,COG2030@2|Bacteria,1R4VU@1224|Proteobacteria,2U1U9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_1068064_1	511051.CSE_13400	1.301e-84	295.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1086460_4	1068978.AMETH_3053	3.62e-41	160.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4E5JA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158351_k127_1086460_1	589865.DaAHT2_2661	5.861e-83	291.0	COG0446@1|root,COG0446@2|Bacteria,1QSGB@1224|Proteobacteria,43A36@68525|delta/epsilon subdivisions,2WZXC@28221|Deltaproteobacteria,2MP72@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_1086460_6	42256.RradSPS_2491	1.809e-09	63.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
SRR25158351_k127_1086460_3	309807.SRU_0328	2.721e-43	164.0	COG0428@1|root,COG0428@2|Bacteria,4PF37@976|Bacteroidetes,1FK2I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
SRR25158351_k127_1086460_2	1448389.BAVQ01000003_gene3509	4.982e-45	181.0	arCOG10456@1|root,2ZA6T@2|Bacteria,2IIHU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1086460_5	1169161.KB897733_gene611	2.408e-22	106.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158351_k127_1086460_0	1394178.AWOO02000036_gene8951	1.145e-115	389.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4EHKU@85012|Streptosporangiales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
SRR25158351_k127_1089451_3	929712.KI912613_gene3853	1.11e-25	121.0	COG0823@1|root,COG0823@2|Bacteria,2I79G@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1089451_4	1380390.JIAT01000009_gene506	1.181e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CTN1@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR25158351_k127_1089451_0	1038869.AXAN01000009_gene4705	3.398e-216	684.0	COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2VM3V@28216|Betaproteobacteria,1K4AE@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158351_k127_1089451_5	1079986.JH164837_gene5451	2.744e-23	102.0	2C19F@1|root,32TZS@2|Bacteria,2IQN6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1089451_2	469383.Cwoe_5297	6.123e-30	138.0	COG3307@1|root,COG3307@2|Bacteria,2HREZ@201174|Actinobacteria,4CTDF@84995|Rubrobacteria	84995|Rubrobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158351_k127_1089451_1	2711.XP_006488031.1	3.015e-34	138.0	COG5272@1|root,KOG0004@2759|Eukaryota,37KHY@33090|Viridiplantae,3G8Q9@35493|Streptophyta	35493|Streptophyta	J	Ubiquitin-40S ribosomal protein	-	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27,ubiquitin
SRR25158351_k127_1089451_6	1394178.AWOO02000056_gene793	1.874e-13	76.0	2B4Q9@1|root,31XGJ@2|Bacteria,2IKKF@201174|Actinobacteria,4EK0N@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1091320_3	1394178.AWOO02000032_gene4905	2.025e-09	60.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4EM18@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158351_k127_1091320_1	367299.JOEE01000012_gene3230	2.513e-16	85.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4FG8R@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158351_k127_1091320_4	1206743.BAGM01000052_gene1356	4.02e-07	62.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4FVX7@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158351_k127_1091320_0	469383.Cwoe_4638	7.189e-184	591.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
SRR25158351_k127_1091320_2	990285.RGCCGE502_34868	1.786e-09	65.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BEA9@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
SRR25158351_k127_1094161_10	926560.KE387023_gene2970	3.256e-27	113.0	COG1622@1|root,COG1622@2|Bacteria,1WJ34@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG1622 Heme copper-type cytochrome quinol oxidase subunit 2	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
SRR25158351_k127_1094161_0	251221.35212730	9.18e-200	653.0	COG0843@1|root,COG0843@2|Bacteria,1G1ME@1117|Cyanobacteria	1117|Cyanobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cyoB	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158351_k127_1094161_5	1380390.JIAT01000014_gene6067	7.331e-51	188.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CSHZ@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158351_k127_1094161_12	469383.Cwoe_1897	7.442e-18	94.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	pbrT	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
SRR25158351_k127_1094161_4	42256.RradSPS_2442	1.66e-53	201.0	COG1028@1|root,COG1028@2|Bacteria,2I4BS@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1094161_6	768066.HELO_4226	4.735e-50	193.0	COG2173@1|root,COG2173@2|Bacteria,1RBFI@1224|Proteobacteria,1S38W@1236|Gammaproteobacteria,1XM8W@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158351_k127_1094161_2	2055.JNXA01000003_gene4256	2.56e-70	257.0	COG0277@1|root,COG0277@2|Bacteria,2IAFM@201174|Actinobacteria	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158351_k127_1094161_8	997346.HMPREF9374_2726	1.277e-37	151.0	COG0584@1|root,COG0584@2|Bacteria,1UWKN@1239|Firmicutes,4I2FI@91061|Bacilli,27CYQ@186824|Thermoactinomycetaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
SRR25158351_k127_1094161_7	1206726.BAFV01000112_gene5550	2.753e-40	166.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria,4G1A2@85025|Nocardiaceae	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3
SRR25158351_k127_1094161_13	479431.Namu_2076	1.03e-12	73.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria,4ERH8@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158351_k127_1094161_1	1122223.KB890688_gene1797	1.111e-71	252.0	COG0382@1|root,COG0382@2|Bacteria,1WI4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158351_k127_1094161_3	479434.Sthe_1412	2.137e-56	206.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,27YFZ@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158351_k127_1094161_11	1382306.JNIM01000001_gene129	4.101e-27	123.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158351_k127_1094161_9	552811.Dehly_0440	1.734e-33	134.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158351_k127_1094612_40	1385518.N798_07910	4.902e-33	134.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4FGIB@85021|Intrasporangiaceae	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158351_k127_1094612_44	1539298.JO41_10485	7.722e-28	120.0	COG0817@1|root,COG0817@2|Bacteria,2J754@203691|Spirochaetes	203691|Spirochaetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158351_k127_1094612_17	266117.Rxyl_1318	2.792e-93	313.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158351_k127_1094612_28	443255.SCLAV_0753	7.724e-58	212.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158351_k127_1094612_8	1089553.Tph_c00140	8.236e-131	423.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,42EVS@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158351_k127_1094612_57	1380390.JIAT01000010_gene4920	4.275e-09	66.0	COG1737@1|root,COG1737@2|Bacteria,2HGPB@201174|Actinobacteria,4CPA9@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158351_k127_1094612_6	1120968.AUBX01000001_gene2180	1.87e-158	527.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158351_k127_1094612_39	479434.Sthe_3506	1.481e-34	148.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2G7EW@200795|Chloroflexi	200795|Chloroflexi	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR25158351_k127_1094612_32	1223521.BBJX01000007_gene1564	1.17e-48	190.0	COG0665@1|root,COG0665@2|Bacteria,1MXD1@1224|Proteobacteria,2VKJ5@28216|Betaproteobacteria,4ADBS@80864|Comamonadaceae	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158351_k127_1094612_55	469383.Cwoe_1905	7.5e-12	73.0	COG0517@1|root,COG0517@2|Bacteria,2I6I8@201174|Actinobacteria,4CQHZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_1094612_53	487521.OCU_33300	3.577e-20	103.0	COG0500@1|root,COG2226@2|Bacteria,2GJ06@201174|Actinobacteria,232P2@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_1094612_29	1283299.AUKG01000001_gene1932	5.909e-57	214.0	COG2385@1|root,COG2385@2|Bacteria,2ID9T@201174|Actinobacteria,4CPMQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158351_k127_1094612_45	469383.Cwoe_5769	5.013e-26	116.0	COG1999@1|root,COG1999@2|Bacteria,2H0F3@201174|Actinobacteria	2|Bacteria	S	SCO1/SenC	hyaE	GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277	-	ko:K03619,ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	HyaE,SCO1-SenC
SRR25158351_k127_1094612_31	479431.Namu_1488	7.232e-50	190.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4ERCE@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158351_k127_1094612_23	1382356.JQMP01000003_gene2195	1.938e-64	234.0	COG1116@1|root,COG1116@2|Bacteria,2G6BU@200795|Chloroflexi,27YRQ@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158351_k127_1094612_33	309801.trd_0598	2.504e-46	181.0	COG0600@1|root,COG0600@2|Bacteria,2G6R1@200795|Chloroflexi,27ZCZ@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
SRR25158351_k127_1094612_24	35754.JNYJ01000001_gene7048	4.584e-64	233.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4DAAE@85008|Micromonosporales	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158351_k127_1094612_60	981369.JQMJ01000004_gene1996	1.443e-05	53.0	COG2104@1|root,COG2104@2|Bacteria,2GQKM@201174|Actinobacteria,2NJUU@228398|Streptacidiphilus	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_1094612_14	469383.Cwoe_0775	2.114e-101	336.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CPZT@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SRR25158351_k127_1094612_21	445975.COLSTE_01682	1.547e-72	265.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,2GKZM@201174|Actinobacteria,4CUQR@84998|Coriobacteriia	84998|Coriobacteriia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158351_k127_1094612_27	28444.JODQ01000006_gene784	3.378e-62	225.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4EJ9J@85012|Streptosporangiales	201174|Actinobacteria	K	TENA/THI-4/PQQC family	-	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
SRR25158351_k127_1094612_46	1089544.KB912942_gene6136	7.11e-26	111.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4E4P1@85010|Pseudonocardiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158351_k127_1094612_38	525904.Tter_2170	3.447e-35	142.0	COG0778@1|root,COG0778@2|Bacteria,2NRS1@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_1094612_37	269800.Tfu_0970	9.367e-36	145.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4EHW3@85012|Streptosporangiales	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158351_k127_1094612_18	1192034.CAP_6873	9.68e-93	314.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2YTZN@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158351_k127_1094612_4	1380390.JIAT01000010_gene4448	1.208e-205	663.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158351_k127_1094612_20	2325.TKV_c20790	4.066e-75	262.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,42ENY@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRR25158351_k127_1094612_59	1172188.KB911821_gene1780	9.591e-06	56.0	COG0454@1|root,COG0456@2|Bacteria,2H5WU@201174|Actinobacteria,4FGPF@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acetyltransferase	-	-	2.3.1.1	ko:K22476	ko00220,ko01210,ko01230,map00220,map01210,map01230	-	R00259	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
SRR25158351_k127_1094612_7	357808.RoseRS_1506	3.387e-132	432.0	COG0031@1|root,COG0031@2|Bacteria,2G5PG@200795|Chloroflexi,3751N@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_1094612_11	1244869.H261_13589	7.95e-109	366.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2JPGW@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1094612_58	90675.XP_010431458.1	6.529e-09	63.0	COG0589@1|root,2RXWD@2759|Eukaryota,389ZY@33090|Viridiplantae,3GX9M@35493|Streptophyta	35493|Streptophyta	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_1094612_51	926554.KI912675_gene2200	6.033e-22	101.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158351_k127_1094612_25	649831.L083_0357	2.671e-63	239.0	COG4626@1|root,COG4626@2|Bacteria,2GNSB@201174|Actinobacteria,4DFGB@85008|Micromonosporales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR25158351_k127_1094612_48	1479623.JHEL01000015_gene728	3.681e-25	109.0	2EMVE@1|root,33FHN@2|Bacteria,2I5BN@201174|Actinobacteria,4FQ15@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1094612_42	1380390.JIAT01000010_gene4430	8.063e-31	127.0	COG1959@1|root,COG1959@2|Bacteria,2HNE1@201174|Actinobacteria,4CQQM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158351_k127_1094612_61	1110697.NCAST_20_00180	6.316e-05	52.0	2ERS7@1|root,32GNJ@2|Bacteria,2HKAC@201174|Actinobacteria,4G82Y@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1094612_3	1121035.AUCH01000015_gene2616	6.701e-256	808.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158351_k127_1094612_56	1206101.AZXC01000012_gene1145	3.951e-10	68.0	2AI3Y@1|root,318HW@2|Bacteria,2IHSQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1094612_15	469383.Cwoe_2903	2.217e-96	328.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158351_k127_1094612_13	637389.Acaty_c1088	4.636e-102	346.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,2NBRA@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158351_k127_1094612_0	32057.KB217478_gene2597	0.0	1272.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,1HKKE@1161|Nostocales	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158351_k127_1094612_19	469383.Cwoe_2902	5.508e-87	295.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
SRR25158351_k127_1094612_49	1463920.JOGB01000006_gene200	1.018e-23	118.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRR25158351_k127_1094612_12	266117.Rxyl_0812	1.934e-103	346.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CPNE@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158351_k127_1094612_43	1380390.JIAT01000016_gene5510	1.643e-29	127.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158351_k127_1094612_50	290397.Adeh_3581	3.704e-22	109.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2Z1V2@29|Myxococcales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158351_k127_1094612_47	469383.Cwoe_2896	2.532e-25	115.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158351_k127_1094612_26	469383.Cwoe_2893	3.595e-63	226.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158351_k127_1094612_22	469383.Cwoe_2891	5.994e-72	261.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4CPNC@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158351_k127_1094612_36	1274374.CBLK010000047_gene2001	5.458e-36	154.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,26XCJ@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158351_k127_1094612_30	690850.Desaf_0491	1.031e-54	212.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2M8WY@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158351_k127_1094612_5	1380390.JIAT01000009_gene1969	7.248e-193	610.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CPK3@84995|Rubrobacteria	84995|Rubrobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158351_k127_1094612_16	1283299.AUKG01000003_gene499	3.56e-95	328.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CQCU@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_1094612_34	926560.KE387023_gene3156	5.927e-41	159.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1WMWX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
SRR25158351_k127_1094612_9	935840.JAEQ01000002_gene3285	1.054e-126	415.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,43HMK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
SRR25158351_k127_1094612_1	1329516.JPST01000008_gene1978	0.0	1159.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,27BGN@186824|Thermoactinomycetaceae	91061|Bacilli	L	ATPases associated with a variety of cellular activities	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158351_k127_1094612_10	82654.Pse7367_0670	1.949e-110	387.0	COG0465@1|root,COG0465@2|Bacteria,1G22Z@1117|Cyanobacteria,1H7W7@1150|Oscillatoriales	1117|Cyanobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158351_k127_1094612_54	1206732.BAGD01000278_gene6348	6.868e-14	81.0	COG0778@1|root,COG0778@2|Bacteria,2IPN9@201174|Actinobacteria,4G1KT@85025|Nocardiaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_1094612_2	1303518.CCALI_00921	1.892e-256	811.0	COG0556@1|root,COG0556@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrB	-	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158351_k127_1094612_41	1122939.ATUD01000002_gene1181	2.217e-31	127.0	COG0346@1|root,COG0346@2|Bacteria,2GY13@201174|Actinobacteria,4CQ1H@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158351_k127_1094612_35	469383.Cwoe_2874	1.995e-38	152.0	COG0741@1|root,COG0741@2|Bacteria,2GWDB@201174|Actinobacteria,4CQ5G@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158351_k127_1094612_52	743836.AYNA01000023_gene2206	6.601e-22	106.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,36YA4@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Dephospho-CoA kinase	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158351_k127_1109056_15	684949.ATTJ01000001_gene1064	5.713e-17	91.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR25158351_k127_1109056_5	709986.Deima_2384	1.001e-69	247.0	COG3823@1|root,COG3823@2|Bacteria,1WM89@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
SRR25158351_k127_1109056_4	1169152.AXVD01000030_gene4513	5.572e-74	253.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
SRR25158351_k127_1109056_2	1206737.BAGF01000151_gene6270	1.473e-106	355.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4FYN0@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158351_k127_1109056_21	390989.JOEG01000027_gene2193	1.054e-07	63.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria,4DMWT@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158351_k127_1109056_10	557598.LHK_02307	1.268e-28	120.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,2WGPE@28216|Betaproteobacteria,2KS1R@206351|Neisseriales	206351|Neisseriales	G	Cupin domain	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
SRR25158351_k127_1109056_13	443906.CMM_0210	5.031e-19	94.0	COG1186@1|root,COG1186@2|Bacteria,2IFEJ@201174|Actinobacteria,4FPCB@85023|Microbacteriaceae	201174|Actinobacteria	J	RF-1 domain	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158351_k127_1109056_19	1120948.KB903247_gene4647	1.645e-11	68.0	2E73E@1|root,33X4K@2|Bacteria,2GV9A@201174|Actinobacteria,4E7YP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1109056_20	1123023.JIAI01000009_gene1117	1.669e-08	64.0	COG4634@1|root,COG4634@2|Bacteria,2H16N@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1109056_22	331113.SNE_A10740	0.0001081	48.0	COG0477@1|root,COG0477@2|Bacteria,2JGWH@204428|Chlamydiae	204428|Chlamydiae	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1109056_0	1108045.GORHZ_055_00060	3.253e-197	627.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4GBCH@85026|Gordoniaceae	201174|Actinobacteria	S	MmgE/PrpD family	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
SRR25158351_k127_1109056_6	448385.sce2493	8.002e-65	233.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42S0M@68525|delta/epsilon subdivisions,2WNYE@28221|Deltaproteobacteria,2YVQZ@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_1109056_18	324602.Caur_2005	3.493e-13	83.0	COG0223@1|root,COG0223@2|Bacteria,2G6VD@200795|Chloroflexi	200795|Chloroflexi	J	PFAM formyl transferase domain protein	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
SRR25158351_k127_1109056_8	981369.JQMJ01000003_gene7876	3.772e-62	223.0	COG4325@1|root,COG4325@2|Bacteria,2GM70@201174|Actinobacteria,2NGVM@228398|Streptacidiphilus	201174|Actinobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1109056_17	1283299.AUKG01000002_gene5052	2.869e-14	74.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CRPE@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1109056_1	710685.MycrhN_1387	2.069e-108	366.0	COG2303@1|root,COG2303@2|Bacteria,2GUQ4@201174|Actinobacteria	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158351_k127_1109056_12	479433.Caci_1074	9.404e-24	106.0	2DUW4@1|root,32UXY@2|Bacteria,2IJWI@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158351_k127_1109056_14	66874.JOFS01000006_gene4300	3.151e-18	94.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1109056_7	1457250.BBMO01000001_gene1293	1.193e-63	229.0	COG2513@1|root,arCOG00581@2157|Archaea,2Y86J@28890|Euryarchaeota,2415K@183963|Halobacteria	183963|Halobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158351_k127_1109056_3	467661.RKLH11_3546	8.18e-84	295.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2TT27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158351_k127_1114390_6	469383.Cwoe_3801	3.857e-16	87.0	28RTZ@1|root,2ZE6B@2|Bacteria,2HQNJ@201174|Actinobacteria,4CS8Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
SRR25158351_k127_1114390_8	1033734.CAET01000068_gene2542	3.97e-08	63.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,1ZDDZ@1386|Bacillus	91061|Bacilli	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158351_k127_1114390_5	404589.Anae109_2152	1.987e-18	92.0	COG1051@1|root,COG1051@2|Bacteria,1QUNH@1224|Proteobacteria,43C4F@68525|delta/epsilon subdivisions,2WS06@28221|Deltaproteobacteria,2Z2IP@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158351_k127_1114390_2	1380390.JIAT01000016_gene5570	2.247e-59	214.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CQT2@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158351_k127_1114390_4	405948.SACE_3707	9.068e-29	132.0	COG0683@1|root,COG0683@2|Bacteria,2H1ZK@201174|Actinobacteria,4EAHR@85010|Pseudonocardiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158351_k127_1114390_0	367299.JOEE01000004_gene1447	1.689e-69	259.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,4FEF6@85021|Intrasporangiaceae	201174|Actinobacteria	L	Contains 3'-5'exonuclease domain	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158351_k127_1114390_10	1380390.JIAT01000010_gene4396	1.155e-05	48.0	COG0346@1|root,COG0346@2|Bacteria,2IHX4@201174|Actinobacteria,4CTQY@84995|Rubrobacteria	84995|Rubrobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1114390_7	103733.JNYO01000006_gene1760	3.81e-14	76.0	COG0346@1|root,COG0346@2|Bacteria,2IHX4@201174|Actinobacteria,4E4SJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1114390_3	102129.Lepto7375DRAFT_3735	2.005e-31	139.0	COG0860@1|root,COG0860@2|Bacteria,1G2V1@1117|Cyanobacteria,1HAS8@1150|Oscillatoriales	1117|Cyanobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,DUF3747
SRR25158351_k127_1114390_9	401526.TcarDRAFT_0374	2.867e-06	58.0	COG5401@1|root,COG5401@2|Bacteria,1V64H@1239|Firmicutes,4H4G2@909932|Negativicutes	909932|Negativicutes	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
SRR25158351_k127_1114390_11	1057002.KB905371_gene407	0.0003254	48.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158351_k127_1114390_1	1122611.KB903947_gene929	4.228e-63	224.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4EGS5@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_1130350_6	365528.KB891286_gene5809	5.254e-33	136.0	COG5500@1|root,COG5500@2|Bacteria,2HU1F@201174|Actinobacteria,4EWCH@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SRR25158351_k127_1130350_8	479432.Sros_9342	1.477e-24	107.0	COG0702@1|root,COG0702@2|Bacteria,2GKXI@201174|Actinobacteria,4EGTZ@85012|Streptosporangiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158351_k127_1130350_2	180281.CPCC7001_1580	5.497e-73	251.0	COG0702@1|root,COG0702@2|Bacteria,1G5F3@1117|Cyanobacteria	1117|Cyanobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158351_k127_1130350_0	469383.Cwoe_0903	1.905e-126	422.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4CPQU@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158351_k127_1130350_9	1454010.JEOE01000001_gene537	1.635e-17	92.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria,4F2YQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158351_k127_1130350_4	748247.AZKH_4418	7.435e-62	224.0	COG1801@1|root,COG1801@2|Bacteria,1N06I@1224|Proteobacteria,2VJZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158351_k127_1130350_5	255470.cbdbA1335	7.249e-57	222.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,34CT3@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HisKA_7TM
SRR25158351_k127_1130350_10	1283299.AUKG01000002_gene4131	1.83e-12	75.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CT29@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158351_k127_1130350_7	196162.Noca_1959	1.272e-30	132.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158351_k127_1130350_3	404589.Anae109_0373	1.248e-70	248.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
SRR25158351_k127_1130350_1	1380390.JIAT01000016_gene5613	1.153e-102	345.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CP6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158351_k127_1134063_13	1304275.C41B8_11763	5.49e-19	89.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transglycosylase associated protein	ymgE	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158351_k127_1134063_10	485913.Krac_7501	8.577e-27	120.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158351_k127_1134063_12	1394178.AWOO02000008_gene3023	5.244e-21	102.0	2F7C9@1|root,33ZTB@2|Bacteria,2H6WW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1134063_3	1048834.TC41_2178	2.294e-156	502.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2784A@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_1134063_11	477974.Daud_1179	3.913e-21	106.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,261WZ@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158351_k127_1134063_18	324602.Caur_2608	1.218e-06	60.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi,375IB@32061|Chloroflexia	32061|Chloroflexia	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRR25158351_k127_1134063_8	1227488.C477_13135	3.711e-31	138.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XV8P@28890|Euryarchaeota,23SAJ@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_1134063_0	1380390.JIAT01000010_gene3508	0.0	1050.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158351_k127_1134063_7	1077972.ARGLB_083_00490	4.563e-32	130.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL
SRR25158351_k127_1134063_15	469383.Cwoe_4250	4.363e-13	73.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1134063_5	469383.Cwoe_4251	2.431e-67	244.0	COG0389@1|root,COG0389@2|Bacteria,2HPPZ@201174|Actinobacteria,4CR2N@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS
SRR25158351_k127_1134063_6	522772.Dacet_2939	6.432e-35	141.0	COG2954@1|root,COG2954@2|Bacteria	2|Bacteria	S	triphosphatase activity	-	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0050355	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158351_k127_1134063_16	1380390.JIAT01000014_gene6066	5.164e-12	75.0	COG1113@1|root,COG1113@2|Bacteria,2HQNZ@201174|Actinobacteria,4CS9Z@84995|Rubrobacteria	84995|Rubrobacteria	E	amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1134063_1	557599.MKAN_18560	5.049e-243	784.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,232MQ@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.8	ko:K01537,ko:K12953	-	-	-	-	ko00000,ko01000	3.A.3,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158351_k127_1134063_14	675635.Psed_4123	5.56e-19	96.0	COG0778@1|root,COG0778@2|Bacteria,2I6AB@201174|Actinobacteria,4E92W@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_1134063_2	1380390.JIAT01000014_gene6211	1.252e-209	681.0	COG0550@1|root,COG0550@2|Bacteria,2GJU7@201174|Actinobacteria,4CPD0@84995|Rubrobacteria	84995|Rubrobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
SRR25158351_k127_1134063_4	1122182.KB903833_gene5397	7.207e-112	370.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DA29@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158351_k127_1134063_9	469383.Cwoe_3063	5.166e-30	130.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria	201174|Actinobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158351_k127_1134946_13	65497.JODV01000002_gene4364	3.582e-76	270.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
SRR25158351_k127_1134946_6	471853.Bcav_2776	4.357e-114	380.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158351_k127_1134946_15	69279.BG36_07465	6.241e-65	233.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,43J4B@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767,ko:K03813	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158351_k127_1134946_17	429009.Adeg_1980	6.139e-55	206.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
SRR25158351_k127_1134946_22	469383.Cwoe_4742	6.095e-32	138.0	COG0735@1|root,COG0735@2|Bacteria,2HTHG@201174|Actinobacteria,4CSV2@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158351_k127_1134946_20	867903.ThesuDRAFT_01585	2.445e-35	146.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WCNE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158351_k127_1134946_7	266117.Rxyl_1742	4.646e-111	378.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_1134946_10	266117.Rxyl_1743	2.239e-83	291.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria,4CT8V@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_1134946_12	1122939.ATUD01000002_gene1308	3.617e-78	279.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CPX5@84995|Rubrobacteria	84995|Rubrobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158351_k127_1134946_8	469383.Cwoe_2648	2.675e-103	338.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158351_k127_1134946_1	1380390.JIAT01000002_gene5978	3.933e-216	676.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158351_k127_1134946_0	469383.Cwoe_2652	2.187e-305	964.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CPR8@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158351_k127_1134946_14	929712.KI912613_gene4647	4.317e-68	256.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1134946_27	266117.Rxyl_1533	2.433e-17	91.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158351_k127_1134946_18	471852.Tcur_1538	1.48e-50	183.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4EIWJ@85012|Streptosporangiales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158351_k127_1134946_23	1298593.TOL_3110	8.204e-32	134.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XK3H@135619|Oceanospirillales	135619|Oceanospirillales	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158351_k127_1134946_2	1380390.JIAT01000002_gene5995	8.495e-192	603.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158351_k127_1134946_21	1380390.JIAT01000002_gene5996	5.892e-35	146.0	COG1792@1|root,COG1792@2|Bacteria,2HP68@201174|Actinobacteria,4CQHY@84995|Rubrobacteria	84995|Rubrobacteria	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158351_k127_1134946_5	469383.Cwoe_2661	4.978e-116	397.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158351_k127_1134946_9	1380390.JIAT01000002_gene5999	2.414e-87	302.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_1134946_30	661087.HMPREF1008_01367	0.000672	51.0	COG3597@1|root,COG3597@2|Bacteria,2GZU9@201174|Actinobacteria,4CVH2@84998|Coriobacteriia	84998|Coriobacteriia	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
SRR25158351_k127_1134946_3	469383.Cwoe_2663	4.73e-143	468.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CPSJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158351_k127_1134946_25	469383.Cwoe_3063	1.301e-26	119.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria	201174|Actinobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158351_k127_1134946_28	1122921.KB898190_gene1359	8.135e-17	84.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,26YFK@186822|Paenibacillaceae	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158351_k127_1134946_24	469383.Cwoe_2665	1.672e-28	116.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CQPP@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158351_k127_1134946_16	926550.CLDAP_12040	8.538e-64	233.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158351_k127_1134946_11	1122939.ATUD01000002_gene1335	3.23e-83	293.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CR1D@84995|Rubrobacteria	84995|Rubrobacteria	E	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158351_k127_1134946_4	469383.Cwoe_2672	2.076e-130	428.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CPDP@84995|Rubrobacteria	84995|Rubrobacteria	E	Aldehyde dehydrogenase family	-	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1134946_19	1118054.CAGW01000017_gene4483	2.25e-41	160.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,26TNS@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158351_k127_1134946_26	235909.GK2520	1.107e-22	104.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,1WGJ5@129337|Geobacillus	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158351_k127_1137526_4	1131553.JIBI01000012_gene832	4.642e-20	93.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,371UZ@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K00616,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158351_k127_1137526_0	47839.CCAU010000004_gene623	7.18e-78	275.0	COG2017@1|root,COG2017@2|Bacteria,2HMIG@201174|Actinobacteria,232CA@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
SRR25158351_k127_1137526_3	469383.Cwoe_0761	4.407e-25	113.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08170	-	M00702	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.23,2.A.1.3.59	-	-	MFS_1
SRR25158351_k127_1137526_2	469383.Cwoe_0761	7.1e-56	207.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08170	-	M00702	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.23,2.A.1.3.59	-	-	MFS_1
SRR25158351_k127_1137526_5	1133849.O3I_013740	5.577e-17	83.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,4FU1E@85025|Nocardiaceae	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_1137526_1	42256.RradSPS_0544	2.972e-61	233.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158351_k127_1137526_6	469383.Cwoe_1000	5.952e-06	54.0	COG0546@1|root,COG0546@2|Bacteria,2HQRV@201174|Actinobacteria,4CSFD@84995|Rubrobacteria	84995|Rubrobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_1140724_2	1380390.JIAT01000009_gene1163	8.082e-122	396.0	COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria,4CQKC@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158351_k127_1140724_3	357808.RoseRS_1298	1.148e-64	229.0	COG2343@1|root,COG2343@2|Bacteria,2GARM@200795|Chloroflexi,3775Q@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_1140724_5	1278073.MYSTI_05295	2.641e-23	103.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158351_k127_1140724_8	273075.Ta0630m	3.432e-09	67.0	COG0500@1|root,arCOG02702@2157|Archaea,2XWS9@28890|Euryarchaeota,242H2@183967|Thermoplasmata	183967|Thermoplasmata	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_1140724_7	1274.HX89_13395	4.456e-12	77.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158351_k127_1140724_4	1229172.JQFA01000002_gene4566	9.409e-26	118.0	COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,1HB1I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158351_k127_1140724_1	1273125.Rrhod_2818	1.36e-125	415.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4FVZV@85025|Nocardiaceae	201174|Actinobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158351_k127_1140724_0	485913.Krac_6683	1.159e-139	455.0	COG0476@1|root,COG0476@2|Bacteria,2G5TN@200795|Chloroflexi	200795|Chloroflexi	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158351_k127_1140724_6	1122939.ATUD01000002_gene1254	2.678e-12	70.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_1146739_3	330214.NIDE4233	1.463e-19	94.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
SRR25158351_k127_1146739_1	1207063.P24_06681	5.165e-87	301.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TS1E@28211|Alphaproteobacteria,2JQ0T@204441|Rhodospirillales	204441|Rhodospirillales	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158351_k127_1146739_4	118166.JH976537_gene2675	5.449e-19	93.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1HC2P@1150|Oscillatoriales	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	dcoH	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158351_k127_1146739_0	1123368.AUIS01000005_gene474	1.383e-101	342.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,2NBYR@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158351_k127_1146739_5	375286.mma_0219	4.435e-11	67.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,2VVTK@28216|Betaproteobacteria,4753V@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158351_k127_1146739_2	309800.C498_18488	2.533e-59	219.0	COG0475@1|root,arCOG01955@2157|Archaea,2XT4U@28890|Euryarchaeota,23SD1@183963|Halobacteria	183963|Halobacteria	P	COG0475 Kef-type K transport systems, membrane components	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158351_k127_1181099_4	1317118.ATO8_20824	1.097e-10	66.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158351_k127_1181099_3	926560.KE387025_gene3981	1.058e-24	117.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1181099_2	557599.MKAN_15555	2.744e-36	155.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	devC	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1181099_0	926560.KE387025_gene3982	1.734e-74	261.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1181099_1	1177181.T9A_01734	1.242e-63	227.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales	135619|Oceanospirillales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
SRR25158351_k127_1183467_2	479434.Sthe_0823	2.48e-63	225.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,27XKS@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158351_k127_1183467_0	469383.Cwoe_4642	3.631e-93	323.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158351_k127_1183467_1	404589.Anae109_2310	3.223e-67	243.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1200632_13	644107.SL1157_0599	5.181e-09	59.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,4NAYH@97050|Ruegeria	28211|Alphaproteobacteria	O	NifU domain protein	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SRR25158351_k127_1200632_3	1206735.BAGG01000027_gene1211	3.449e-59	216.0	COG0500@1|root,COG2226@2|Bacteria,2IMIR@201174|Actinobacteria,4FZ5H@85025|Nocardiaceae	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_1200632_4	28444.JODQ01000007_gene5157	4.65e-57	219.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4EGMA@85012|Streptosporangiales	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158351_k127_1200632_7	479435.Kfla_7040	2.339e-45	183.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4DR1B@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_1200632_2	1463861.JNXE01000025_gene3109	6.758e-62	220.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1200632_11	479432.Sros_5901	1.436e-20	100.0	COG2072@1|root,COG2072@2|Bacteria,2I3HA@201174|Actinobacteria	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1200632_12	479431.Namu_3367	9.328e-14	81.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria,4EUFU@85013|Frankiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	GO:0005575,GO:0005576	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
SRR25158351_k127_1200632_14	935866.JAER01000059_gene277	9.504e-05	53.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	GO:0005575,GO:0005576	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
SRR25158351_k127_1200632_5	927658.AJUM01000034_gene541	8.452e-57	214.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,2FP63@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR25158351_k127_1200632_6	118173.KB235914_gene2492	5.759e-47	174.0	COG4803@1|root,COG4803@2|Bacteria,1G531@1117|Cyanobacteria,1HB6E@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158351_k127_1200632_1	457570.Nther_1748	1.375e-72	257.0	COG0388@1|root,COG0388@2|Bacteria,1V357@1239|Firmicutes,24GBQ@186801|Clostridia	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_1200632_10	1131813.AQVT01000001_gene2850	1.978e-22	114.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,1JV4Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Malectin
SRR25158351_k127_1200632_9	381666.H16_B2025	2.233e-23	104.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1KEBW@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Ribonuclease B OB domain	cspA3	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158351_k127_1200632_0	356851.JOAN01000012_gene5082	3.292e-77	273.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4D92R@85008|Micromonosporales	201174|Actinobacteria	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158351_k127_1200632_8	1192034.CAP_7431	2.335e-40	159.0	COG0508@1|root,COG0508@2|Bacteria,1Q4SN@1224|Proteobacteria,437G3@68525|delta/epsilon subdivisions,2X2NP@28221|Deltaproteobacteria,2YU1R@29|Myxococcales	28221|Deltaproteobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR25158351_k127_1203247_11	1214101.BN159_1370	1.371e-12	76.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	MA20_13990	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	Lactamase_B
SRR25158351_k127_1203247_5	1283299.AUKG01000001_gene1443	6.712e-33	134.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158351_k127_1203247_3	118161.KB235922_gene223	3.133e-78	272.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,3VJFW@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR25158351_k127_1203247_13	208439.AJAP_06285	2.097e-09	67.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4E0IN@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158351_k127_1203247_0	378806.STAUR_5864	0.0	1071.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YUBF@29|Myxococcales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158351_k127_1203247_7	469383.Cwoe_0801	1.479e-30	125.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CQCY@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158351_k127_1203247_2	351607.Acel_2117	7.85e-100	342.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4ERZT@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_1203247_9	42256.RradSPS_0658	9.613e-26	116.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CQBV@84995|Rubrobacteria	84995|Rubrobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158351_k127_1203247_1	469383.Cwoe_0798	3.55e-282	891.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CP69@84995|Rubrobacteria	84995|Rubrobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158351_k127_1203247_8	469383.Cwoe_3668	4.686e-26	119.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4CTEF@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1203247_6	1463885.KL578491_gene5767	7.025e-32	129.0	2AY0M@1|root,31Q26@2|Bacteria,2IMBI@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158351_k127_1203247_12	661087.HMPREF1008_01737	3.746e-10	68.0	COG0797@1|root,COG4942@1|root,COG0797@2|Bacteria,COG4942@2|Bacteria,2GSPY@201174|Actinobacteria,4CUPI@84998|Coriobacteriia	84998|Coriobacteriia	M	Psort location Extracellular, score 9.55	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
SRR25158351_k127_1203247_4	436229.JOEH01000014_gene6189	6.069e-72	259.0	arCOG06766@1|root,2Z87F@2|Bacteria,2IAM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1203247_10	1499967.BAYZ01000098_gene4388	1.036e-14	74.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1223353_2	1283299.AUKG01000001_gene3471	5.517e-43	162.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4CT8A@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158351_k127_1223353_7	526225.Gobs_0199	1.986e-09	68.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria,4EWAH@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158351_k127_1223353_0	269797.Mbar_A3070	1.349e-96	330.0	COG0025@1|root,arCOG01961@2157|Archaea,2Y0UK@28890|Euryarchaeota,2NBGR@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158351_k127_1223353_9	411489.CLOL250_00503	0.0001746	44.0	2EG8N@1|root,33A0G@2|Bacteria,1UPXM@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1223353_5	1278073.MYSTI_01297	2.878e-33	144.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158351_k127_1223353_4	1242864.D187_000264	2.724e-36	154.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158351_k127_1223353_8	207954.MED92_08371	2.899e-07	57.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,1RPKZ@1236|Gammaproteobacteria,1XH6Z@135619|Oceanospirillales	135619|Oceanospirillales	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1223353_3	743718.Isova_2447	1.26e-39	155.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4F4RM@85017|Promicromonosporaceae	201174|Actinobacteria	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158351_k127_1223353_1	1183438.GKIL_1213	2.17e-51	190.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158351_k127_1223353_6	585529.HMPREF0291_10109	1.123e-14	78.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,22K91@1653|Corynebacteriaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1232125_12	867845.KI911784_gene3292	4.799e-33	136.0	COG2343@1|root,COG2343@2|Bacteria,2G79F@200795|Chloroflexi,377I0@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_1232125_8	1121381.JNIV01000090_gene223	5.085e-87	306.0	COG1249@1|root,COG1249@2|Bacteria,1WM2Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_1232125_14	1172188.KB911821_gene2047	8.81e-22	108.0	COG0546@1|root,COG0546@2|Bacteria,2I9FC@201174|Actinobacteria,4FGUD@85021|Intrasporangiaceae	201174|Actinobacteria	S	HAD family hydrolase	-	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158351_k127_1232125_3	525897.Dbac_2436	4.06e-141	478.0	COG2230@1|root,COG3496@1|root,COG2230@2|Bacteria,COG3496@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WKGA@28221|Deltaproteobacteria,2MA3I@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,DUF1365
SRR25158351_k127_1232125_4	666685.R2APBS1_0202	2.191e-114	382.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1X4I0@135614|Xanthomonadales	135614|Xanthomonadales	S	NAD FAD-binding protein	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158351_k127_1232125_7	1380390.JIAT01000017_gene5247	7.665e-88	302.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria,4CP9B@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158351_k127_1232125_19	443218.AS9A_3117	8.826e-05	53.0	COG1073@1|root,COG1073@2|Bacteria,2I30Z@201174|Actinobacteria,2390E@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158351_k127_1232125_5	696747.NIES39_Q02600	1.12e-106	357.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158351_k127_1232125_13	582515.KR51_00009050	8.725e-30	121.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria	1117|Cyanobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158351_k127_1232125_2	1173021.ALWA01000038_gene1736	2.312e-141	464.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158351_k127_1232125_10	2074.JNYD01000015_gene4547	7.378e-39	163.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4E8W7@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1232125_1	1122939.ATUD01000006_gene1750	6.642e-153	497.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4CRA5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158351_k127_1232125_6	1122939.ATUD01000006_gene1751	6.455e-89	306.0	COG1294@1|root,COG1294@2|Bacteria,2GN42@201174|Actinobacteria,4CRFG@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158351_k127_1232125_11	1120948.KB903219_gene792	9.401e-39	151.0	COG0748@1|root,COG0748@2|Bacteria,2I2RZ@201174|Actinobacteria,4EFAD@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_1232125_9	469383.Cwoe_4252	1.505e-45	178.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IDNP@201174|Actinobacteria,4CTVG@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1232125_0	1042377.AFPJ01000036_gene1233	1.096e-188	604.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
SRR25158351_k127_1232125_16	469383.Cwoe_1913	7.402e-18	95.0	COG0392@1|root,COG0392@2|Bacteria,2HQ3T@201174|Actinobacteria,4CRKA@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158351_k127_1237932_1	469383.Cwoe_0016	8.632e-72	259.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CP9M@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158351_k127_1237932_0	469383.Cwoe_0015	7.269e-99	338.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_1237932_2	1283299.AUKG01000001_gene1749	2.281e-61	232.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158351_k127_1237932_5	1380390.JIAT01000009_gene1780	3.106e-14	85.0	COG1716@1|root,COG1716@2|Bacteria,2HM1E@201174|Actinobacteria,4CQ7B@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158351_k127_1237932_3	1380390.JIAT01000009_gene1781	1.945e-48	187.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158351_k127_1237932_4	1151126.AQYI01000006_gene3291	3.194e-44	181.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FM1Q@85023|Microbacteriaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_1244554_2	526225.Gobs_3746	4.779e-17	86.0	2EE1U@1|root,337WK@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
SRR25158351_k127_1244554_4	1502850.FG91_00795	3.949e-08	64.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3,PD40
SRR25158351_k127_1244554_0	1041522.MCOL_V214069	0.0	1095.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,2GKP2@201174|Actinobacteria,233SK@1762|Mycobacteriaceae	201174|Actinobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	HA,Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
SRR25158351_k127_1244554_3	526226.Gbro_3084	1.815e-09	68.0	2CKUX@1|root,32SD2@2|Bacteria,2IQH0@201174|Actinobacteria,4GF3Z@85026|Gordoniaceae	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2
SRR25158351_k127_1244554_1	1323361.JPOC01000063_gene252	1.464e-19	89.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4G0C8@85025|Nocardiaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158351_k127_1246427_18	469383.Cwoe_3772	7.521e-83	289.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1246427_14	1380390.JIAT01000010_gene4143	5.282e-100	338.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CPF5@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158351_k127_1246427_15	1380390.JIAT01000010_gene4142	2.307e-90	314.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CPND@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1246427_9	469383.Cwoe_3774	6.689e-119	402.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1246427_11	469383.Cwoe_3775	1.094e-116	396.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158351_k127_1246427_16	469383.Cwoe_3777	1.446e-86	298.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CPWG@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158351_k127_1246427_29	309801.trd_0055	1.018e-23	106.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,27YAY@189775|Thermomicrobia	189775|Thermomicrobia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158351_k127_1246427_26	1232410.KI421416_gene2635	1.065e-40	162.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,43UEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Putative peptidoglycan binding domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
SRR25158351_k127_1246427_32	1283299.AUKG01000002_gene4008	1.953e-15	83.0	COG5607@1|root,COG5607@2|Bacteria,2HP25@201174|Actinobacteria,4CQD1@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158351_k127_1246427_28	1380390.JIAT01000001_gene5042	2.193e-24	109.0	COG5607@1|root,COG5607@2|Bacteria,2HP53@201174|Actinobacteria,4CQGX@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158351_k127_1246427_42	1385518.N798_11200	8.395e-05	53.0	COG3409@1|root,COG3409@2|Bacteria,2IDIJ@201174|Actinobacteria,4FF8V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158351_k127_1246427_30	1131462.DCF50_p673	6.507e-19	97.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,261N2@186807|Peptococcaceae	186801|Clostridia	M	PFAM Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158351_k127_1246427_35	1033736.CAHK01000016_gene768	6.414e-13	80.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4FAVZ@85019|Brevibacteriaceae	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158351_k127_1246427_34	1283299.AUKG01000002_gene4607	3.826e-13	81.0	COG4965@1|root,COG4965@2|Bacteria,2HPA4@201174|Actinobacteria,4CQND@84995|Rubrobacteria	84995|Rubrobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158351_k127_1246427_12	429009.Adeg_1041	1.696e-105	354.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,42FW4@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158351_k127_1246427_38	58123.JOFJ01000015_gene4394	3.956e-08	64.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,4EN3F@85012|Streptosporangiales	201174|Actinobacteria	D	ATPase MipZ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg,TadE
SRR25158351_k127_1246427_36	1283299.AUKG01000002_gene4603	5.316e-10	70.0	COG3745@1|root,COG3745@2|Bacteria,2HP19@201174|Actinobacteria,4CQBK@84995|Rubrobacteria	84995|Rubrobacteria	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158351_k127_1246427_24	469383.Cwoe_3789	7.094e-54	198.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CS4E@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1246427_33	85643.Tmz1t_2697	1.845e-14	79.0	COG1430@1|root,COG1430@2|Bacteria,1N7U4@1224|Proteobacteria,2VWGX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158351_k127_1246427_21	469383.Cwoe_3796	1.596e-60	221.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CT4V@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158351_k127_1246427_25	767817.Desgi_2527	6.123e-41	163.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
SRR25158351_k127_1246427_8	309803.CTN_0122	9.146e-123	404.0	COG0498@1|root,COG0498@2|Bacteria,2GCQK@200918|Thermotogae	200918|Thermotogae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0546	PALP
SRR25158351_k127_1246427_13	1035308.AQYY01000001_gene2529	3.756e-102	355.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,2600D@186807|Peptococcaceae	186801|Clostridia	E	PFAM Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158351_k127_1246427_10	935845.JADQ01000014_gene3427	1.832e-117	392.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,26SHB@186822|Paenibacillaceae	91061|Bacilli	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158351_k127_1246427_39	479434.Sthe_3226	1.454e-06	59.0	COG0508@1|root,COG2267@1|root,COG0508@2|Bacteria,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	acoC	-	1.11.1.10,2.3.1.12,3.8.1.5	ko:K00433,ko:K00627,ko:K01563,ko:K06889	ko00010,ko00020,ko00361,ko00620,ko00625,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00361,map00620,map00625,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569,R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC00004,RC01317,RC01340,RC01341,RC02013,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Biotin_lipoyl
SRR25158351_k127_1246427_19	266117.Rxyl_2949	3.22e-82	287.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158351_k127_1246427_41	1463881.KL591002_gene4637	4.447e-06	55.0	2EMIB@1|root,33F6Y@2|Bacteria,2INVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1246427_27	1464048.JNZS01000007_gene4510	2.683e-25	114.0	2E8HM@1|root,332VQ@2|Bacteria,2IGA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRR25158351_k127_1246427_37	1230457.C476_08758	4.424e-09	67.0	arCOG07560@1|root,arCOG10180@1|root,arCOG07560@2157|Archaea,arCOG10180@2157|Archaea,2XUY5@28890|Euryarchaeota,23U72@183963|Halobacteria	183963|Halobacteria	S	membrane-bound metal-dependent	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
SRR25158351_k127_1246427_23	469383.Cwoe_1788	7.859e-56	211.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,4CPU0@84995|Rubrobacteria	84995|Rubrobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158351_k127_1246427_40	1380390.JIAT01000015_gene5798	1.808e-06	58.0	2A2D1@1|root,30QQ1@2|Bacteria,2HRBZ@201174|Actinobacteria,4CT9D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1246427_5	1380390.JIAT01000015_gene5797	4.7e-176	573.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CRCE@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158351_k127_1246427_31	929712.KI912613_gene3039	1.121e-17	91.0	COG2332@1|root,COG2332@2|Bacteria,2HP5E@201174|Actinobacteria,4CQHD@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmE	-	-	-	-	-	-	-	-	-	-	-	-	CcmE
SRR25158351_k127_1246427_7	1232410.KI421420_gene3170	1.022e-127	424.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,43S0N@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Divalent cation transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158351_k127_1246427_22	518766.Rmar_1889	3.561e-56	205.0	COG0432@1|root,COG0432@2|Bacteria,4NNMN@976|Bacteroidetes,1FK4I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158351_k127_1246427_17	1211815.CBYP010000014_gene3514	1.586e-86	300.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158351_k127_1246427_6	1122939.ATUD01000004_gene3930	3.408e-129	427.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CPER@84995|Rubrobacteria	84995|Rubrobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158351_k127_1246427_2	1122939.ATUD01000004_gene3931	9.281e-222	708.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4CP80@84995|Rubrobacteria	84995|Rubrobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158351_k127_1246427_0	1283299.AUKG01000002_gene3678	4.878e-299	934.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158351_k127_1246427_4	1380390.JIAT01000009_gene543	2.556e-182	587.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4CPTF@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158351_k127_1246427_1	1464048.JNZS01000010_gene5163	2.395e-255	810.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4D8UN@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158351_k127_1246427_3	1122939.ATUD01000004_gene3937	6.869e-201	651.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4CPMZ@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158351_k127_1246427_20	1173022.Cri9333_4061	3.034e-75	260.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1G2UN@1117|Cyanobacteria,1H977@1150|Oscillatoriales	1117|Cyanobacteria	G	Alpha amylase, catalytic domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158351_k127_1250957_6	65393.PCC7424_4751	1.301e-66	246.0	COG0823@1|root,COG0823@2|Bacteria,1G6E9@1117|Cyanobacteria	1117|Cyanobacteria	MU	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
SRR25158351_k127_1250957_3	1205680.CAKO01000037_gene1250	1.769e-111	374.0	COG2141@1|root,COG2141@2|Bacteria,1NKS6@1224|Proteobacteria,2TT87@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1250957_9	1121019.AUMN01000010_gene2060	2.165e-28	132.0	COG0665@1|root,COG0665@2|Bacteria,2HYMK@201174|Actinobacteria,1W8RU@1268|Micrococcaceae	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158351_k127_1250957_14	383372.Rcas_0344	3.174e-05	55.0	COG0558@1|root,COG0558@2|Bacteria,2GASR@200795|Chloroflexi,3778P@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_1250957_0	1370121.AUWS01000026_gene3120	1.514e-262	824.0	COG0028@1|root,COG0028@2|Bacteria,2GIX3@201174|Actinobacteria,2376B@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_1250957_2	929712.KI912613_gene4278	6.436e-131	438.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CPQ3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1250957_12	309807.SRU_0698	2.122e-09	60.0	COG2343@1|root,COG2343@2|Bacteria,4NSIC@976|Bacteroidetes,1FKB2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_1250957_11	929712.KI912613_gene3681	4.199e-12	79.0	COG2149@1|root,COG2149@2|Bacteria,2HTN4@201174|Actinobacteria,4CSZK@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158351_k127_1250957_13	1304865.JAGF01000001_gene348	2.454e-06	60.0	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158351_k127_1250957_15	34007.IT40_04470	0.0007338	47.0	2DBSJ@1|root,2ZASJ@2|Bacteria,1R9SK@1224|Proteobacteria,2U3RK@28211|Alphaproteobacteria,2PYQI@265|Paracoccus	28211|Alphaproteobacteria	S	ETC complex I subunit conserved region	-	-	-	-	-	-	-	-	-	-	-	-	ETC_C1_NDUFA4
SRR25158351_k127_1250957_5	675635.Psed_1294	7.731e-93	323.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4E97Z@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_1250957_8	871963.Desdi_2181	1.799e-35	145.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,261MJ@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_1250957_7	404380.Gbem_0574	1.234e-40	164.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,43UMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158351_k127_1250957_4	469383.Cwoe_5367	3.815e-100	336.0	COG1469@1|root,COG1469@2|Bacteria,2IBX9@201174|Actinobacteria	201174|Actinobacteria	S	Type I GTP cyclohydrolase folE2	-	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
SRR25158351_k127_1250957_1	469383.Cwoe_5366	5.37e-144	466.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1250957_10	1283299.AUKG01000002_gene4070	6.916e-25	108.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CPSW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1258231_10	941824.TCEL_00756	7.658e-14	83.0	COG1376@1|root,COG1376@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia,36KPB@31979|Clostridiaceae	186801|Clostridia	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
SRR25158351_k127_1258231_8	443255.SCLAV_3852	1.277e-17	84.0	2E3SC@1|root,32YPX@2|Bacteria,2GQRK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158351_k127_1258231_3	1123388.AQWU01000073_gene1140	9.281e-71	247.0	COG4932@1|root,COG5624@1|root,COG4932@2|Bacteria,COG5624@2|Bacteria,1WJK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1258231_6	1348657.M622_04425	4.948e-35	149.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_1258231_1	525904.Tter_1356	9.314e-115	400.0	COG1193@1|root,COG1193@2|Bacteria,2NNS1@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158351_k127_1258231_5	1283299.AUKG01000001_gene2796	3.072e-47	184.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CR97@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158351_k127_1258231_11	1283299.AUKG01000001_gene3034	1.6e-11	73.0	2EN95@1|root,31MIY@2|Bacteria,2HQ7Y@201174|Actinobacteria,4CRR5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1258231_9	1449347.JQLN01000001_gene552	7.081e-14	82.0	COG1277@1|root,COG1277@2|Bacteria,2I1PA@201174|Actinobacteria,2M4NW@2063|Kitasatospora	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158351_k127_1258231_4	66429.JOFL01000001_gene4463	1.675e-69	246.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1258231_0	324602.Caur_3505	5.837e-125	415.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158351_k127_1258231_7	1280947.HY30_10480	7.359e-28	124.0	COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,2U3PZ@28211|Alphaproteobacteria,43Y4R@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158351_k127_1258231_2	644966.Tmar_1443	2.799e-73	257.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia	186801|Clostridia	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158351_k127_1259447_0	469383.Cwoe_3200	1.915e-101	340.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CPT1@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158351_k127_1259447_2	1476583.DEIPH_ctg017orf0115	1.77e-57	206.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158351_k127_1259447_1	1283299.AUKG01000002_gene5207	1.243e-89	306.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,4CRBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158351_k127_1259447_3	42256.RradSPS_0210	1.729e-40	158.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4CQCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158351_k127_1271696_6	1206720.BAFQ01000013_gene421	4.603e-06	51.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4FV03@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158351_k127_1271696_3	469383.Cwoe_1692	1.777e-49	188.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158351_k127_1271696_1	1380390.JIAT01000014_gene6270	1.521e-75	261.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1271696_0	479434.Sthe_1087	1.353e-79	273.0	COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,27Y1A@189775|Thermomicrobia	189775|Thermomicrobia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158351_k127_1271696_5	469383.Cwoe_1783	1.318e-15	79.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1271696_2	479434.Sthe_1085	3.368e-50	184.0	arCOG04740@1|root,31PZA@2|Bacteria,2GA0B@200795|Chloroflexi,27Y9E@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1271696_4	469383.Cwoe_5388	4.453e-29	119.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_1300024_13	428125.CLOLEP_03869	4.983e-47	185.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158351_k127_1300024_3	645991.Sgly_3007	8.508e-113	381.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	degT1	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158351_k127_1300024_8	1122939.ATUD01000013_gene858	3.393e-90	311.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158351_k127_1300024_1	1380390.JIAT01000009_gene1705	9.834e-170	554.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4CP9E@84995|Rubrobacteria	84995|Rubrobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158351_k127_1300024_9	290397.Adeh_2268	4.749e-88	299.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase type 11	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_1300024_7	1120983.KB894571_gene2141	4.441e-91	319.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,2UCNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158351_k127_1300024_15	266117.Rxyl_0906	4.162e-23	105.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4CQQK@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158351_k127_1300024_0	1380390.JIAT01000009_gene2234	1.08e-285	897.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPRA@84995|Rubrobacteria	84995|Rubrobacteria	O	Lon protease (S16) C-terminal proteolytic domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158351_k127_1300024_10	1151061.CAJY01000028_gene1065	3.459e-59	216.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158351_k127_1300024_11	264732.Moth_1825	7.349e-57	214.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,42I6P@68295|Thermoanaerobacterales	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158351_k127_1300024_6	1158318.ATXC01000001_gene468	1.776e-93	323.0	COG0029@1|root,COG0029@2|Bacteria	2|Bacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158351_k127_1300024_5	1380390.JIAT01000009_gene1703	3.209e-94	317.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4CRSB@84995|Rubrobacteria	84995|Rubrobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158351_k127_1300024_2	525904.Tter_0039	1.243e-134	444.0	COG2046@1|root,COG2046@2|Bacteria,2NNS5@2323|unclassified Bacteria	2|Bacteria	P	PUA-like domain	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158351_k127_1300024_12	479432.Sros_5512	8.594e-55	209.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria	201174|Actinobacteria	O	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Pyr_redox_2
SRR25158351_k127_1300024_4	526225.Gobs_2962	9.194e-106	359.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158351_k127_1300024_14	469383.Cwoe_3182	1.137e-34	141.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158351_k127_1309856_12	469383.Cwoe_1903	1.469e-18	90.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria	201174|Actinobacteria	C	I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158351_k127_1309856_4	1380394.JADL01000001_gene3101	4.035e-74	265.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2JV5D@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
SRR25158351_k127_1309856_2	1382306.JNIM01000001_gene4039	1.928e-84	290.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158351_k127_1309856_13	1187851.A33M_4157	6.928e-18	97.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria,3FDYA@34008|Rhodovulum	28211|Alphaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158351_k127_1309856_0	1313172.YM304_26380	3.139e-143	478.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CMS1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158351_k127_1309856_8	1128421.JAGA01000002_gene1222	9.76e-40	161.0	COG0277@1|root,COG0277@2|Bacteria,2NP55@2323|unclassified Bacteria	2|Bacteria	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158351_k127_1309856_3	1137271.AZUM01000004_gene4211	2.167e-79	279.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DYFJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR25158351_k127_1309856_11	37919.EP51_27425	2.305e-24	112.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4FUWJ@85025|Nocardiaceae	201174|Actinobacteria	E	Protein involved in amino acid-polyamine transporter activity, L-gamma-aminobutyric acid transporter activity and gamma-aminobutyric acid transport	gabP	-	-	ko:K03293,ko:K11735,ko:K16237	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.12,2.A.3.1.4,2.A.3.1.5	-	iNJ661.Rv0522	AA_permease
SRR25158351_k127_1309856_7	706587.Desti_5045	2.473e-49	186.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2WS0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158351_k127_1309856_10	1385520.N802_14465	3.539e-29	129.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4FGG7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Von Willebrand factor A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158351_k127_1309856_5	219305.MCAG_01032	1.209e-56	211.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4D9TC@85008|Micromonosporales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158351_k127_1309856_6	1211815.CBYP010000068_gene212	2.706e-51	194.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4ES3V@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158351_k127_1309856_1	1121272.KB903252_gene943	2.029e-108	365.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4D8TR@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158351_k127_1309856_9	519989.ECTPHS_01769	2.68e-37	153.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_1309856_14	469383.Cwoe_3093	0.0001189	52.0	2EKS7@1|root,33EFZ@2|Bacteria,2HE9S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1321967_42	63418.F2Q3R9	9.041e-07	59.0	COG0500@1|root,KOG3010@2759|Eukaryota,39XVG@33154|Opisthokonta,3NX1I@4751|Fungi,3QNGG@4890|Ascomycota,20EGC@147545|Eurotiomycetes,3B66F@33183|Onygenales,3FXTG@34384|Arthrodermataceae	4751|Fungi	Q	Methyltransferase small domain	TMT1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464,GO:0046547	2.1.1.145	ko:K22438	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_1321967_33	591158.SSMG_04749	9.073e-28	126.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158351_k127_1321967_36	1121468.AUBR01000001_gene556	5.824e-21	94.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,42GUA@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU
SRR25158351_k127_1321967_44	1123024.AUII01000023_gene262	0.0002298	44.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_1321967_43	929712.KI912613_gene285	2.384e-06	55.0	2AXD0@1|root,31PCB@2|Bacteria,2HRSN@201174|Actinobacteria,4CTVR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1321967_41	1206101.AZXC01000018_gene5393	8.161e-07	60.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158351_k127_1321967_40	525268.HMPREF0308_2208	1.551e-07	58.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,22KD7@1653|Corynebacteriaceae	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158351_k127_1321967_0	1125863.JAFN01000001_gene929	3.001e-199	645.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158351_k127_1321967_19	266117.Rxyl_2310	2.17e-51	190.0	COG0546@1|root,COG0546@2|Bacteria,2I9FC@201174|Actinobacteria,4CTYC@84995|Rubrobacteria	84995|Rubrobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158351_k127_1321967_11	266117.Rxyl_2311	1.236e-72	256.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4CQ4H@84995|Rubrobacteria	84995|Rubrobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158351_k127_1321967_5	1123242.JH636435_gene2044	1.026e-99	346.0	COG3961@1|root,COG3961@2|Bacteria,2IY2K@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_1321967_14	266117.Rxyl_2123	1.355e-63	230.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CQ1A@84995|Rubrobacteria	84995|Rubrobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158351_k127_1321967_25	1121445.ATUZ01000011_gene782	2.946e-35	138.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MC54@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158351_k127_1321967_4	1380390.JIAT01000011_gene2615	3.656e-113	378.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158351_k127_1321967_7	1380390.JIAT01000011_gene2614	1.478e-78	267.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CQ5S@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158351_k127_1321967_17	1283299.AUKG01000001_gene2656	2.673e-59	207.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CPZ7@84995|Rubrobacteria	84995|Rubrobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158351_k127_1321967_20	1449126.JQKL01000050_gene2698	8.242e-51	186.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,26987@186813|unclassified Clostridiales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158351_k127_1321967_38	1299327.I546_0424	1.467e-09	70.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,23ANF@1762|Mycobacteriaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158351_k127_1321967_28	633131.TR2A62_2823	2.112e-30	125.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
SRR25158351_k127_1321967_31	1298867.AUES01000016_gene3928	3.354e-29	122.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,3JQSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158351_k127_1321967_8	867903.ThesuDRAFT_00580	1.018e-76	268.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WCH7@538999|Clostridiales incertae sedis	186801|Clostridia	E	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158351_k127_1321967_18	1158318.ATXC01000001_gene1253	6.058e-58	208.0	COG0563@1|root,COG0563@2|Bacteria,2G42Z@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
SRR25158351_k127_1321967_2	1122939.ATUD01000003_gene3586	4.485e-150	485.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158351_k127_1321967_26	469383.Cwoe_1359	1.495e-33	139.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158351_k127_1321967_37	1236902.ANAS01000019_gene4274	8.467e-11	65.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4EKGM@85012|Streptosporangiales	201174|Actinobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158351_k127_1321967_10	1122939.ATUD01000003_gene3583	4.16e-73	261.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158351_k127_1321967_27	936140.AEOT01000005_gene56	9.151e-32	127.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158351_k127_1321967_12	1122939.ATUD01000003_gene3581	1.188e-71	246.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158351_k127_1321967_21	273068.TTE2277	2.104e-44	166.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,42G9H@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158351_k127_1321967_34	1122939.ATUD01000003_gene3579	2.181e-24	105.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CQKA@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158351_k127_1321967_13	266117.Rxyl_2143	3.78e-71	247.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158351_k127_1321967_30	383381.EH30_07980	1.344e-29	124.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,2K52R@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158351_k127_1321967_16	469383.Cwoe_1350	5.173e-60	209.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158351_k127_1321967_35	1408322.JHYK01000004_gene871	9.304e-23	100.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,27NW5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158351_k127_1321967_39	1220551.SCHR_06120	1.054e-07	55.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,4GZK8@90964|Staphylococcaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158351_k127_1321967_15	469383.Cwoe_1347	5.096e-63	228.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CQ15@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158351_k127_1321967_6	469383.Cwoe_1346	7.499e-97	324.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CPWK@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158351_k127_1321967_29	740709.A10D4_07320	3.175e-30	126.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,2QG65@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158351_k127_1321967_23	273068.TTE2289	1.183e-42	157.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,42GJK@68295|Thermoanaerobacterales	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158351_k127_1321967_3	502558.EGYY_24430	7.849e-124	402.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CUAA@84998|Coriobacteriia	84998|Coriobacteriia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158351_k127_1321967_32	469383.Cwoe_1342	3.384e-29	120.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CQIU@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158351_k127_1321967_24	1380390.JIAT01000011_gene2589	1.833e-42	175.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CPXR@84995|Rubrobacteria	84995|Rubrobacteria	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158351_k127_1321967_9	1283299.AUKG01000001_gene2631	9.15e-75	256.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CPFD@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158351_k127_1321967_22	67373.JOBF01000008_gene3505	2.49e-44	164.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158351_k127_1321967_1	626939.HMPREF9443_00688	6.638e-154	490.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes	909932|Negativicutes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158351_k127_1327487_1	469383.Cwoe_3036	1.083e-52	197.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158351_k127_1327487_3	1304872.JAGC01000009_gene443	5.398e-23	102.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2MBU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158351_k127_1327487_0	469383.Cwoe_3034	1.618e-234	756.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158351_k127_1327487_2	1283299.AUKG01000001_gene2660	4.61e-35	138.0	COG2329@1|root,COG2329@2|Bacteria,2IM1Q@201174|Actinobacteria,4CTW9@84995|Rubrobacteria	84995|Rubrobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158351_k127_1327487_5	1236902.ANAS01000041_gene4371	0.0007844	42.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4EI5Q@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158351_k127_133231_7	479431.Namu_4737	4.924e-23	109.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
SRR25158351_k127_133231_3	591167.Sfla_3238	1.099e-58	211.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_133231_8	1089551.KE386572_gene2178	9.984e-05	53.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,4BQHE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158351_k127_133231_4	1440774.Y900_023145	7.807e-28	118.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria,23APA@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
SRR25158351_k127_133231_2	469383.Cwoe_4668	4.818e-98	328.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CPVA@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158351_k127_133231_0	929712.KI912613_gene2834	7.046e-117	392.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CRHI@84995|Rubrobacteria	84995|Rubrobacteria	D	Tubulin/FtsZ family, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C,Tubulin
SRR25158351_k127_133231_1	469383.Cwoe_4666	1.542e-111	378.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158351_k127_133231_5	1122939.ATUD01000012_gene3145	8.877e-25	115.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_133231_6	1122939.ATUD01000017_gene4025	2.792e-23	109.0	COG2802@1|root,COG2802@2|Bacteria,2HP4R@201174|Actinobacteria,4CQGD@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
SRR25158351_k127_1342232_3	1121271.AUCM01000004_gene970	2.525e-16	88.0	COG1073@1|root,COG1073@2|Bacteria,1N0UG@1224|Proteobacteria,2U19N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Bile_Hydr_Trans
SRR25158351_k127_1342232_0	557599.MKAN_04810	1.62e-53	193.0	COG0412@1|root,COG0412@2|Bacteria,2ISE7@201174|Actinobacteria,23B25@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	SnoaL_2
SRR25158351_k127_1342232_2	270374.MELB17_05082	2.722e-30	124.0	COG2199@1|root,COG3706@2|Bacteria,1RGNS@1224|Proteobacteria,1S5DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9
SRR25158351_k127_1342232_1	1229780.BN381_410017	2.811e-38	157.0	COG1787@1|root,COG1787@2|Bacteria	2|Bacteria	V	Restriction endonuclease	mrr	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat,TerD,zf-C4_Topoisom
SRR25158351_k127_136158_14	1123501.KB902315_gene3315	4.851e-05	46.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158351_k127_136158_10	521393.JH806632_gene894	2.097e-24	107.0	COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4D5MG@85005|Actinomycetales	201174|Actinobacteria	J	Endoribonuclease L-PSP	psp1	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158351_k127_136158_7	264732.Moth_1363	6.89e-39	163.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,42FZG@68295|Thermoanaerobacterales	186801|Clostridia	H	Polynucleotide adenylyltransferase region	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158351_k127_136158_8	562970.Btus_1844	2.493e-32	141.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,278FY@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the multicopper oxidase YfiH RL5 family	ylmD	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158351_k127_136158_6	266117.Rxyl_1487	5.946e-42	174.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158351_k127_136158_3	1283299.AUKG01000002_gene4919	3.073e-64	224.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158351_k127_136158_9	156889.Mmc1_3656	8.815e-31	132.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158351_k127_136158_12	485916.Dtox_1085	6.97e-15	79.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	ylmG	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158351_k127_136158_13	748247.AZKH_3845	6.283e-08	61.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,2KX5K@206389|Rhodocyclales	206389|Rhodocyclales	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158351_k127_136158_11	1064535.MELS_0895	3.745e-20	98.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4H53B@909932|Negativicutes	909932|Negativicutes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158351_k127_136158_1	469383.Cwoe_3518	3.877e-90	306.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158351_k127_136158_2	469383.Cwoe_3517	1.846e-85	294.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CQ0Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158351_k127_136158_5	382464.ABSI01000010_gene3699	1.314e-57	208.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia,2IU52@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158351_k127_136158_0	1380390.JIAT01000010_gene4534	4.537e-102	338.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158351_k127_136158_4	1196324.A374_12455	1.215e-61	217.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158351_k127_1369320_1	1128421.JAGA01000002_gene1348	4.28e-229	719.0	COG4799@1|root,COG4799@2|Bacteria,2NNWQ@2323|unclassified Bacteria	2|Bacteria	I	carboxyl transferase	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158351_k127_1369320_2	42256.RradSPS_0454	1.387e-187	603.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4CP7I@84995|Rubrobacteria	84995|Rubrobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158351_k127_1369320_9	1192034.CAP_7093	1.531e-06	59.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria	1224|Proteobacteria	LO	WD-40 repeat	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	NACHT,Pentapeptide,WD40
SRR25158351_k127_1369320_8	414996.IL38_08530	2.882e-13	81.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,407QZ@622450|Actinopolysporales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158351_k127_1369320_5	1324957.K933_15912	1.317e-45	175.0	COG1063@1|root,arCOG01459@2157|Archaea,2XT5M@28890|Euryarchaeota,23UBG@183963|Halobacteria	183963|Halobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158351_k127_1369320_0	1048339.KB913029_gene2507	3.807e-278	871.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU9G@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1369320_7	1449347.JQLN01000005_gene4197	7.881e-27	117.0	COG2128@1|root,COG2128@2|Bacteria,2HSVU@201174|Actinobacteria,2M3IY@2063|Kitasatospora	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_1369320_6	929712.KI912613_gene3702	4.059e-35	137.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158351_k127_1369320_3	469383.Cwoe_5543	7.536e-140	460.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158351_k127_1369320_4	1380390.JIAT01000009_gene2137	1.212e-119	397.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158351_k127_1386878_0	469383.Cwoe_5241	3.315e-91	319.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158351_k127_1386878_2	469383.Cwoe_5242	2.981e-44	168.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CQJ6@84995|Rubrobacteria	84995|Rubrobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158351_k127_1386878_3	698769.JFBD01000043_gene610	1.533e-40	159.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,4C5HI@84406|Virgibacillus	91061|Bacilli	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158351_k127_1386878_1	1298867.AUES01000040_gene988	3.537e-65	227.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria,3JX1U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158351_k127_1386878_4	768671.ThimaDRAFT_2127	2.162e-15	77.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1RZYZ@1236|Gammaproteobacteria,1X0SQ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158351_k127_1399450_3	1173021.ALWA01000022_gene653	5.457e-69	241.0	COG0535@1|root,COG0535@2|Bacteria,1G1TV@1117|Cyanobacteria	1117|Cyanobacteria	S	Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
SRR25158351_k127_1399450_0	469383.Cwoe_3075	7.164e-93	315.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158351_k127_1399450_2	58123.JOFJ01000004_gene1667	1.161e-79	280.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4EFY7@85012|Streptosporangiales	201174|Actinobacteria	S	FIST_C	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158351_k127_1399450_10	1380390.JIAT01000014_gene6121	9.275e-06	52.0	2BCFA@1|root,3260X@2|Bacteria,2HBC1@201174|Actinobacteria,4CT3V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158351_k127_1399450_6	1463909.KL585972_gene3593	2.985e-55	203.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158351_k127_1399450_1	1235279.C772_02944	1.568e-91	310.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,26DRI@186818|Planococcaceae	91061|Bacilli	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158351_k127_1399450_5	518766.Rmar_1552	1.862e-55	208.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1FJ15@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158351_k127_1399450_8	469383.Cwoe_4930	5.793e-30	130.0	COG2199@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5278@2|Bacteria,2IA4H@201174|Actinobacteria,4CP5Q@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
SRR25158351_k127_1399450_11	1380390.JIAT01000010_gene4371	3.667e-05	53.0	COG0671@1|root,COG0671@2|Bacteria,2HQWJ@201174|Actinobacteria,4CSPJ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158351_k127_1399450_9	1121380.JNIW01000094_gene3709	2.73e-23	106.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158351_k127_1399450_7	469383.Cwoe_1671	8.187e-42	169.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CQ9P@84995|Rubrobacteria	84995|Rubrobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR25158351_k127_1399450_4	1380390.JIAT01000011_gene2837	1.794e-67	237.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158351_k127_1410986_4	469383.Cwoe_3741	7.556e-22	101.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
SRR25158351_k127_1410986_2	118161.KB235922_gene1057	1.99e-45	172.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,3VJV5@52604|Pleurocapsales	1117|Cyanobacteria	KT	COGs COG0317 Guanosine polyphosphate pyrophosphohydrolase synthetase	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
SRR25158351_k127_1410986_6	1463879.JOHP01000006_gene6129	1.111e-06	59.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	MA20_16090	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1410986_3	68219.JNXI01000011_gene5194	2.38e-42	159.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158351_k127_1410986_5	1283299.AUKG01000002_gene5121	1.298e-15	83.0	2DS52@1|root,33EJF@2|Bacteria,2H1N9@201174|Actinobacteria,4CST5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1410986_1	1278073.MYSTI_01086	1.809e-63	230.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42RF4@68525|delta/epsilon subdivisions,2WPIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM ROK family protein	glkA	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158351_k127_1410986_0	373994.Riv7116_5818	1.143e-253	807.0	COG1554@1|root,COG1554@2|Bacteria,1G0DN@1117|Cyanobacteria,1HIEI@1161|Nostocales	1117|Cyanobacteria	G	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158351_k127_1415824_3	1094980.Mpsy_3112	3.26e-73	267.0	COG2304@1|root,arCOG02900@2157|Archaea,2Y2GH@28890|Euryarchaeota,2NAGB@224756|Methanomicrobia	224756|Methanomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1415824_6	3218.PP1S91_35V6.1	2.463e-24	108.0	COG0580@1|root,KOG0223@2759|Eukaryota,37I8V@33090|Viridiplantae,3GEXA@35493|Streptophyta	35493|Streptophyta	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006833,GO:0008150,GO:0015250,GO:0015267,GO:0015318,GO:0015840,GO:0016020,GO:0016021,GO:0019755,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042044,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8.12	-	-	MIP
SRR25158351_k127_1415824_8	1123368.AUIS01000006_gene677	2.613e-14	81.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,1RPKU@1236|Gammaproteobacteria,2NDEA@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158351_k127_1415824_4	479434.Sthe_1371	1.068e-49	183.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158351_k127_1415824_9	696281.Desru_2109	1.587e-12	71.0	COG0639@1|root,COG0639@2|Bacteria,1UYWK@1239|Firmicutes,25DVG@186801|Clostridia,2603Q@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM phosphodiesterase, MJ0936	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158351_k127_1415824_2	1123024.AUII01000004_gene1521	4.939e-90	303.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DZUQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158351_k127_1415824_7	290397.Adeh_1024	2.401e-20	94.0	COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,42VTU@68525|delta/epsilon subdivisions,2WRGJ@28221|Deltaproteobacteria,2YVHK@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158351_k127_1415824_5	456442.Mboo_0176	4.463e-25	117.0	COG2226@1|root,arCOG01779@2157|Archaea	2157|Archaea	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1415824_0	1283299.AUKG01000001_gene2449	2.35e-136	470.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CRG8@84995|Rubrobacteria	84995|Rubrobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,MASE1
SRR25158351_k127_1415824_10	987059.RBXJA2T_10636	0.0004263	51.0	COG0454@1|root,COG0456@2|Bacteria,1R8GF@1224|Proteobacteria,2VNUV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,PilZ
SRR25158351_k127_1415824_1	1267535.KB906767_gene3854	4.176e-101	335.0	COG1023@1|root,COG1023@2|Bacteria,3Y2ZP@57723|Acidobacteria,2JJT6@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158351_k127_1454554_7	1283299.AUKG01000002_gene5203	7.272e-122	401.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158351_k127_1454554_23	469383.Cwoe_3202	1.588e-44	169.0	COG1335@1|root,COG1335@2|Bacteria,2GPXN@201174|Actinobacteria,4CQB9@84995|Rubrobacteria	84995|Rubrobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158351_k127_1454554_9	324602.Caur_0865	2.694e-99	340.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,3755X@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158351_k127_1454554_0	469383.Cwoe_3204	0.0	1159.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CPEA@84995|Rubrobacteria	84995|Rubrobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158351_k127_1454554_26	1283299.AUKG01000002_gene5199	3.854e-38	145.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1454554_21	1122939.ATUD01000005_gene2711	1.874e-50	188.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158351_k127_1454554_11	1392502.JNIO01000008_gene1844	4.585e-96	332.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158351_k127_1454554_12	1380390.JIAT01000010_gene4847	5.471e-90	307.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CPNA@84995|Rubrobacteria	84995|Rubrobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158351_k127_1454554_33	886293.Sinac_2139	2.599e-11	75.0	COG1721@1|root,COG1721@2|Bacteria,2IY4G@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158351_k127_1454554_24	469383.Cwoe_3214	2.217e-43	182.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CQFZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158351_k127_1454554_30	1380390.JIAT01000010_gene4844	1.895e-14	80.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria,4CSUA@84995|Rubrobacteria	84995|Rubrobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1454554_31	1121926.AXWO01000005_gene613	1.282e-13	79.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4EYP1@85014|Glycomycetales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158351_k127_1454554_25	1305732.JAGG01000001_gene1818	8.112e-40	153.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4FPNM@85023|Microbacteriaceae	201174|Actinobacteria	J	D-Tyr-tRNA(Tyr) deacylase	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158351_k127_1454554_29	929712.KI912613_gene3558	1.98e-19	100.0	COG0779@1|root,COG0779@2|Bacteria,2HPFT@201174|Actinobacteria,4CQU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158351_k127_1454554_4	469383.Cwoe_3219	1.171e-158	513.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158351_k127_1454554_34	762963.HMPREF9056_02682	1.425e-10	65.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,4D61T@85005|Actinomycetales	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158351_k127_1454554_3	1121422.AUMW01000003_gene950	2.616e-189	625.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158351_k127_1454554_36	1120950.KB892747_gene3690	8.142e-09	63.0	COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria,4DSC7@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158351_k127_1454554_32	1485544.JQKP01000015_gene2072	1.845e-13	74.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,44VW4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158351_k127_1454554_20	1283299.AUKG01000002_gene5187	3.436e-58	217.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158351_k127_1454554_18	1122939.ATUD01000005_gene2721	1.732e-60	222.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CPY4@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_N
SRR25158351_k127_1454554_17	1121946.AUAX01000034_gene6829	1.293e-70	250.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4D8XR@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158351_k127_1454554_27	714961.BFZC1_01852	6.098e-31	124.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3IY82@400634|Lysinibacillus	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158351_k127_1454554_1	1430331.EP10_17210	1.587e-224	717.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1WFAI@129337|Geobacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158351_k127_1454554_8	469383.Cwoe_3233	1.138e-117	394.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158351_k127_1454554_14	1313172.YM304_28250	3.571e-81	281.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_1454554_10	1240349.ANGC01000006_gene1489	1.049e-98	331.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4FXQ8@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1454554_19	1380390.JIAT01000010_gene4830	5.726e-60	228.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158351_k127_1454554_37	1227487.C474_09759	1.019e-05	53.0	arCOG02998@1|root,arCOG02998@2157|Archaea,2XXUK@28890|Euryarchaeota,23WB2@183963|Halobacteria	183963|Halobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_1454554_22	469383.Cwoe_2871	6.254e-49	191.0	COG0644@1|root,COG0644@2|Bacteria,2HQ8K@201174|Actinobacteria,4CRS9@84995|Rubrobacteria	84995|Rubrobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1454554_38	1216932.CM240_0617	5.811e-05	52.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,36E5Y@31979|Clostridiaceae	186801|Clostridia	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR25158351_k127_1454554_39	105425.BBPL01000003_gene6761	9.822e-05	47.0	COG3324@1|root,COG3324@2|Bacteria,2GP30@201174|Actinobacteria,2NHPX@228398|Streptacidiphilus	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158351_k127_1454554_16	1283299.AUKG01000002_gene5170	1.077e-79	276.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CPRX@84995|Rubrobacteria	84995|Rubrobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158351_k127_1454554_6	1380390.JIAT01000010_gene4822	4.301e-142	471.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CPQX@84995|Rubrobacteria	84995|Rubrobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158351_k127_1454554_2	469383.Cwoe_3241	4.591e-195	636.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158351_k127_1454554_28	429009.Adeg_1943	1.964e-23	110.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,42J4X@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158351_k127_1454554_15	1122939.ATUD01000005_gene2754	1.37e-80	283.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4CPMK@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158351_k127_1454554_35	1528106.JRJE01000032_gene3082	7.464e-10	67.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,2JSQA@204441|Rhodospirillales	204441|Rhodospirillales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158351_k127_1454554_5	28444.JODQ01000001_gene2647	2.597e-152	489.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4EGN4@85012|Streptosporangiales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158351_k127_1454554_13	1122939.ATUD01000005_gene2757	8.129e-89	299.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158351_k127_1464508_4	469383.Cwoe_3249	1.812e-75	258.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158351_k127_1464508_12	1074488.AGBX01000005_gene2742	1.006e-34	145.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4FCGC@85020|Dermabacteraceae	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158351_k127_1464508_8	1166948.JPZL01000003_gene498	1.553e-56	207.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XHA1@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158351_k127_1464508_0	469383.Cwoe_3257	4.494e-156	501.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1464508_11	469383.Cwoe_3260	1.158e-43	163.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158351_k127_1464508_5	138119.DSY4018	1.303e-71	249.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,260S1@186807|Peptococcaceae	186801|Clostridia	H	PFAM CobB CobQ-like glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158351_k127_1464508_17	1192034.CAP_8509	2.54e-13	81.0	COG0500@1|root,COG0500@2|Bacteria,1R0DM@1224|Proteobacteria,43CW7@68525|delta/epsilon subdivisions,2X847@28221|Deltaproteobacteria,2Z3KJ@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_1464508_1	1380390.JIAT01000010_gene4782	9.7e-123	411.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158351_k127_1464508_13	1007103.AFHW01000061_gene3933	7.373e-34	139.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,26QCU@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158351_k127_1464508_9	525909.Afer_1991	9.18e-55	203.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CNHS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_1464508_14	869210.Marky_0059	4.425e-30	128.0	COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1WK9S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158351_k127_1464508_10	1380390.JIAT01000013_gene64	2.185e-48	179.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158351_k127_1464508_3	1173028.ANKO01000144_gene1500	8.491e-87	301.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1H7C2@1150|Oscillatoriales	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_1464508_2	469383.Cwoe_4683	4.383e-122	404.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1464508_15	929712.KI912613_gene413	1.811e-25	119.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
SRR25158351_k127_1464508_7	1313172.YM304_13530	2.692e-64	231.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria	201174|Actinobacteria	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158351_k127_1464508_6	1380390.JIAT01000010_gene4281	2.269e-70	251.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1464508_16	266940.Krad_3974	2.169e-16	89.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158351_k127_1464508_18	266940.Krad_3975	0.000408	43.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1467011_5	247634.GPB2148_3437	3.583e-10	67.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1J53Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158351_k127_1467011_0	1380393.JHVP01000003_gene1104	6.034e-163	532.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158351_k127_1467011_2	1380370.JIBA01000015_gene98	5.727e-133	456.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158351_k127_1467011_3	1380356.JNIK01000014_gene3480	2.221e-77	269.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158351_k127_1467011_1	331113.SNE_A06750	3.823e-161	525.0	COG0664@1|root,COG1252@1|root,COG0664@2|Bacteria,COG1252@2|Bacteria,2JFCT@204428|Chlamydiae	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885,ko:K10716	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Abhydrolase_6,CBS,Ion_trans,Pyr_redox_2,cNMP_binding
SRR25158351_k127_1467011_4	1502851.FG93_05168	5.298e-75	261.0	COG2114@1|root,COG2114@2|Bacteria,1P8ZU@1224|Proteobacteria,2TRC7@28211|Alphaproteobacteria,3JUCZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158351_k127_1472984_1	1380390.JIAT01000016_gene5648	1.18e-57	216.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4CPP2@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158351_k127_1472984_4	768706.Desor_5034	1.179e-10	73.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,260KF@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158351_k127_1472984_3	1121423.JONT01000001_gene1956	8.027e-11	65.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,262UM@186807|Peptococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158351_k127_1472984_0	469383.Cwoe_2836	6.383e-121	407.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158351_k127_1472984_2	436229.JOEH01000019_gene6656	8.069e-30	133.0	COG5640@1|root,COG5640@2|Bacteria,2GN18@201174|Actinobacteria,2NFVN@228398|Streptacidiphilus	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	3.4.21.4	ko:K01312	ko04080,ko04972,ko04974,ko05164,map04080,map04972,map04974,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Trypsin
SRR25158351_k127_1472984_5	479431.Namu_1557	3.331e-05	46.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4ERZ3@85013|Frankiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158351_k127_1478567_1	1304885.AUEY01000054_gene163	1.385e-56	201.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_1478567_0	101510.RHA1_ro05648	1.874e-173	574.0	COG2937@1|root,COG2937@2|Bacteria,2GMQF@201174|Actinobacteria,4FWRE@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158351_k127_1478567_2	420324.KI912045_gene4612	5.51e-05	49.0	2EHHF@1|root,33B9C@2|Bacteria,1N3NN@1224|Proteobacteria,2UC59@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1486369_6	42256.RradSPS_1313	2.259e-41	160.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4CQE1@84995|Rubrobacteria	84995|Rubrobacteria	I	6-phosphogluconate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158351_k127_1486369_12	1128421.JAGA01000003_gene2949	1.292e-05	57.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158351_k127_1486369_9	1380393.JHVP01000012_gene2724	1.574e-28	122.0	COG3358@1|root,COG3358@2|Bacteria,2GP66@201174|Actinobacteria,4EVG7@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158351_k127_1486369_11	797299.HALLA_19360	1.183e-08	61.0	COG3358@1|root,arCOG04570@2157|Archaea,2XWQ3@28890|Euryarchaeota,23V6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158351_k127_1486369_5	471852.Tcur_3301	1.069e-47	182.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4EFGS@85012|Streptosporangiales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158351_k127_1486369_0	765912.Thimo_1592	0.0	1424.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1WXPZ@135613|Chromatiales	135613|Chromatiales	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158351_k127_1486369_8	469383.Cwoe_4191	1.558e-28	118.0	COG2127@1|root,COG2127@2|Bacteria,2HPG0@201174|Actinobacteria,4CQUJ@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158351_k127_1486369_4	1380394.JADL01000001_gene2522	7.239e-84	299.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TS3K@28211|Alphaproteobacteria,2JRPY@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_1486369_7	765420.OSCT_1817	1.547e-32	136.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi,377UC@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158351_k127_1486369_3	796606.BMMGA3_11330	1.593e-103	352.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	bfmBC	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_1486369_1	656024.FsymDg_0989	1.226e-118	396.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4ES2Q@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158351_k127_1487253_1	469383.Cwoe_2872	2.542e-173	556.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158351_k127_1487253_3	357808.RoseRS_0759	7.298e-06	50.0	COG0484@1|root,COG0484@2|Bacteria,2GBJA@200795|Chloroflexi,375XN@32061|Chloroflexia	32061|Chloroflexia	OP	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SRR25158351_k127_1487253_0	926692.AZYG01000038_gene1081	4.358e-181	597.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WAIG@53433|Halanaerobiales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158351_k127_1487253_2	1306406.ASHX01000001_gene1822	2.251e-13	78.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_1496510_4	929712.KI912613_gene959	2.12e-25	106.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CP8M@84995|Rubrobacteria	84995|Rubrobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_1496510_0	56110.Oscil6304_3325	1.471e-160	519.0	COG2308@1|root,COG2308@2|Bacteria,1G0JF@1117|Cyanobacteria,1H7MS@1150|Oscillatoriales	1117|Cyanobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158351_k127_1496510_3	745776.DGo_CA0868	2.498e-38	161.0	COG2307@1|root,COG2307@2|Bacteria,1WM8F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRR25158351_k127_1496510_2	1122917.KB899659_gene5918	4.344e-52	194.0	COG1305@1|root,COG1305@2|Bacteria,1V4HE@1239|Firmicutes,4HF4E@91061|Bacilli,26UF4@186822|Paenibacillaceae	91061|Bacilli	E	transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158351_k127_1496510_1	469383.Cwoe_2648	2.095e-102	335.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158351_k127_1496510_5	1283299.AUKG01000001_gene1985	1.674e-09	62.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_1496639_4	1380390.JIAT01000009_gene2177	7.236e-109	370.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CP93@84995|Rubrobacteria	84995|Rubrobacteria	GM	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158351_k127_1496639_8	1242864.D187_008859	3.049e-56	212.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158351_k127_1496639_11	675635.Psed_4404	2.445e-36	153.0	COG1670@1|root,COG1670@2|Bacteria,2IFMK@201174|Actinobacteria,4E3F3@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57,2.3.1.82	ko:K00657,ko:K00663	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_8
SRR25158351_k127_1496639_10	1206744.BAGL01000065_gene4899	4.758e-48	178.0	COG0500@1|root,COG2226@2|Bacteria,2HJCZ@201174|Actinobacteria,4G6D4@85025|Nocardiaceae	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_1496639_2	479434.Sthe_3342	1.378e-254	803.0	COG2217@1|root,COG2217@2|Bacteria,2G5S4@200795|Chloroflexi,27YT0@189775|Thermomicrobia	189775|Thermomicrobia	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158351_k127_1496639_12	1435356.Y013_05145	4.306e-35	143.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4FWK9@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_1496639_5	469383.Cwoe_0759	3.144e-83	292.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,2I9RZ@201174|Actinobacteria	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158351_k127_1496639_16	1380390.JIAT01000009_gene562	0.0001398	49.0	2AWFQ@1|root,31NBZ@2|Bacteria,2HQYB@201174|Actinobacteria,4CSQU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1496639_13	290397.Adeh_0738	2.195e-34	145.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158351_k127_1496639_3	1283299.AUKG01000002_gene4290	3.312e-217	681.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158351_k127_1496639_0	469383.Cwoe_1618	1.1e-322	1002.0	COG3968@1|root,COG3968@2|Bacteria,2GMA9@201174|Actinobacteria,4CS2J@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158351_k127_1496639_9	42256.RradSPS_1796	4.361e-53	208.0	COG2508@1|root,COG2508@2|Bacteria,2HJJI@201174|Actinobacteria,4CPT6@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158351_k127_1496639_14	1121422.AUMW01000022_gene1554	6.112e-13	81.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC4@186801|Clostridia,262GR@186807|Peptococcaceae	186801|Clostridia	EH	PFAM Aminotransferase, class IV	ilvE2	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_1496639_7	1238182.C882_3065	5.842e-57	216.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2JPJN@204441|Rhodospirillales	204441|Rhodospirillales	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85	ko:K01665,ko:K13950	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind,GATase
SRR25158351_k127_1496639_6	105425.BBPL01000032_gene4706	4.196e-75	270.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,2NIRH@228398|Streptacidiphilus	201174|Actinobacteria	S	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,BAAT_C,DUF1100
SRR25158351_k127_1496639_1	502025.Hoch_5119	2.163e-282	892.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158351_k127_1496639_15	195250.CM001776_gene1729	4.338e-12	76.0	2DUA0@1|root,33PJB@2|Bacteria,1GD0Q@1117|Cyanobacteria,1H0Y9@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_150686_8	1380390.JIAT01000009_gene385	1.426e-22	98.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPUT@84995|Rubrobacteria	84995|Rubrobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_150686_7	469383.Cwoe_4714	8.027e-45	182.0	COG2199@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5
SRR25158351_k127_150686_0	100226.SCO3462	2.652e-157	513.0	COG0535@1|root,COG0535@2|Bacteria,2HP1A@201174|Actinobacteria	201174|Actinobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_150686_2	1906.SFRA_03310	4.382e-103	351.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4873
SRR25158351_k127_150686_6	1380390.JIAT01000010_gene4157	2.871e-47	172.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158351_k127_150686_4	1122939.ATUD01000023_gene3973	4.72e-89	306.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CP79@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_150686_1	266117.Rxyl_1489	7.261e-138	448.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158351_k127_150686_9	1283299.AUKG01000002_gene4623	5.929e-17	93.0	COG1589@1|root,COG1589@2|Bacteria,2HPRM@201174|Actinobacteria,4CR4Y@84995|Rubrobacteria	84995|Rubrobacteria	M	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158351_k127_150686_5	1183438.GKIL_2493	6.291e-55	204.0	COG0812@1|root,COG0812@2|Bacteria,1FZXZ@1117|Cyanobacteria	1117|Cyanobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158351_k127_150686_3	44060.JODL01000035_gene3328	6.547e-98	338.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1518890_16	469383.Cwoe_0478	9.229e-06	49.0	COG5164@1|root,COG5164@2|Bacteria,2HCYM@201174|Actinobacteria,4CU0T@84995|Rubrobacteria	84995|Rubrobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1518890_8	1188256.BASI01000002_gene3381	1.617e-73	258.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TR41@28211|Alphaproteobacteria,3FD6I@34008|Rhodovulum	28211|Alphaproteobacteria	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158351_k127_1518890_17	35754.JNYJ01000012_gene939	0.0001751	53.0	2DBF7@1|root,2Z8X0@2|Bacteria,2I0F0@201174|Actinobacteria,4DBGG@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158351_k127_1518890_2	1449976.KALB_2204	2.682e-114	380.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158351_k127_1518890_5	460265.Mnod_1590	9.081e-103	342.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,1JRQZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_1518890_7	1037409.BJ6T_72360	2.681e-77	279.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8,Trans_reg_C
SRR25158351_k127_1518890_3	219305.MCAG_00927	7.164e-113	367.0	COG0702@1|root,COG0702@2|Bacteria,2HVU1@201174|Actinobacteria,4D8HF@85008|Micromonosporales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158351_k127_1518890_1	485913.Krac_4927	8.639e-117	394.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158351_k127_1518890_4	1487953.JMKF01000095_gene5210	2.893e-105	361.0	COG2027@1|root,COG2027@2|Bacteria,1G1K9@1117|Cyanobacteria,1H702@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158351_k127_1518890_9	1306406.ASHX01000001_gene1252	6.568e-73	255.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_1518890_6	1348663.KCH_31450	9.122e-85	288.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,2M22M@2063|Kitasatospora	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1518890_15	1123023.JIAI01000003_gene2921	4.138e-06	57.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,4DZU6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1518890_11	314256.OG2516_13279	3.781e-45	177.0	COG1309@1|root,COG1309@2|Bacteria,1RBV0@1224|Proteobacteria,2U7VY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1518890_10	546414.Deide_02070	1.892e-67	234.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_1518890_12	710111.FraQA3DRAFT_3341	2.418e-14	80.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1518890_14	196162.Noca_0969	3.837e-06	53.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1518890_13	765910.MARPU_03490	3.118e-10	70.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1518890_0	1242864.D187_002420	1.405e-157	519.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2YX9E@29|Myxococcales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRR25158351_k127_1520841_18	498761.HM1_3148	4.279e-29	117.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1520841_19	1382230.ASAP_2763	6.413e-26	110.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1520841_21	1329516.JPST01000070_gene1945	6.098e-12	73.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes,4I01W@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1520841_9	266117.Rxyl_1311	1.161e-124	411.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CPR4@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158351_k127_1520841_16	935261.JAGL01000013_gene3617	5.583e-58	211.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,2U7N6@28211|Alphaproteobacteria,43JXZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158351_k127_1520841_7	1380390.JIAT01000010_gene4503	5.319e-133	439.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158351_k127_1520841_11	370438.PTH_1115	3.873e-111	372.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,2.6.1.102	ko:K12452,ko:K13010	ko00520,map00520	-	R03391,R03392,R10460	RC00006,RC00230,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158351_k127_1520841_1	469383.Cwoe_3546	3.925e-185	593.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158351_k127_1520841_8	469383.Cwoe_3547	6.809e-128	416.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_1520841_10	1163408.UU9_08802	1.603e-117	389.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales	135614|Xanthomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_1520841_14	1303518.CCALI_02738	2.276e-66	234.0	COG0066@1|root,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158351_k127_1520841_0	292459.STH2116	1.229e-205	651.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158351_k127_1520841_3	1283299.AUKG01000002_gene4882	5.467e-167	550.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CP5R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158351_k127_1520841_13	1343740.M271_45110	6.032e-82	275.0	COG3558@1|root,COG3558@2|Bacteria,2IFFG@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
SRR25158351_k127_1520841_4	469383.Cwoe_3561	1.013e-158	516.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CP5W@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158351_k127_1520841_12	330214.NIDE3444	6.896e-94	321.0	COG0075@1|root,COG0075@2|Bacteria,3J0FC@40117|Nitrospirae	40117|Nitrospirae	E	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158351_k127_1520841_6	317619.ANKN01000211_gene2150	3.491e-146	471.0	COG0059@1|root,COG0059@2|Bacteria,1G0NQ@1117|Cyanobacteria,1MKRF@1212|Prochloraceae	1117|Cyanobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158351_k127_1520841_17	479432.Sros_8058	2.283e-55	201.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4EFRV@85012|Streptosporangiales	201174|Actinobacteria	E	Small subunit of acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158351_k127_1520841_15	644548.SCNU_12467	2.384e-60	216.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4GBT5@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1520841_5	42256.RradSPS_0719	1.698e-150	496.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158351_k127_1520841_2	710111.FraQA3DRAFT_5740	8.3e-168	541.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4ES8T@85013|Frankiales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158351_k127_1535849_5	469383.Cwoe_3741	2.402e-116	391.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
SRR25158351_k127_1535849_1	436229.JOEH01000051_gene6274	1.047e-169	560.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria	201174|Actinobacteria	T	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_1535849_19	1123024.AUII01000036_gene3162	1.354e-07	61.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4E4A4@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
SRR25158351_k127_1535849_12	1229780.BN381_130188	1.053e-32	140.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria	201174|Actinobacteria	T	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158351_k127_1535849_20	1089453.GOSPT_099_00550	0.0002447	54.0	COG2373@1|root,COG2931@1|root,COG3391@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Lactonase
SRR25158351_k127_1535849_16	935863.AWZR01000003_gene2591	8.345e-23	105.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1X49X@135614|Xanthomonadales	135614|Xanthomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158351_k127_1535849_7	526227.Mesil_2489	1.844e-89	319.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158351_k127_1535849_8	2074.JNYD01000019_gene2461	5.259e-86	301.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4E5I7@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158351_k127_1535849_14	1122611.KB903974_gene3005	1.064e-25	111.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4EI2N@85012|Streptosporangiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
SRR25158351_k127_1535849_9	1283299.AUKG01000003_gene566	1.519e-70	250.0	COG0005@1|root,COG0005@2|Bacteria,2GKGG@201174|Actinobacteria,4CPSX@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158351_k127_1535849_11	2002.JOEQ01000025_gene239	2.753e-53	198.0	COG3361@1|root,COG3361@2|Bacteria,2I6N0@201174|Actinobacteria,4EKCC@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158351_k127_1535849_3	649638.Trad_1102	3.008e-165	532.0	COG1233@1|root,COG1233@2|Bacteria,1WM3K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158351_k127_1535849_10	400668.Mmwyl1_1953	5.455e-70	250.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2,5.3.1.9	ko:K00616,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158351_k127_1535849_0	1163617.SCD_n00855	0.0	1223.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158351_k127_1535849_4	404589.Anae109_4127	1.639e-135	458.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,2YU5E@29|Myxococcales	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158351_k127_1535849_2	1163617.SCD_n00853	5.193e-169	550.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Dehydrogenase	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_1535849_6	1463857.JOFZ01000001_gene5526	8.779e-106	356.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158351_k127_1535849_18	1120797.KB908256_gene1980	2.972e-09	65.0	2B6F7@1|root,31ZD7@2|Bacteria,2IPXY@201174|Actinobacteria,238Y0@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1535849_17	42256.RradSPS_1920	1.432e-21	98.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CQCQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158351_k127_1535849_15	1123023.JIAI01000002_gene4693	4.908e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4E6UD@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM 'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158351_k127_1535849_13	1246448.ANAZ01000004_gene4792	2.231e-30	124.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4EIGX@85012|Streptosporangiales	201174|Actinobacteria	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158351_k127_1540679_0	313625.BL107_11181	1.363e-37	156.0	COG3527@1|root,COG3527@2|Bacteria,1G5JS@1117|Cyanobacteria,1GZ7Q@1129|Synechococcus	1117|Cyanobacteria	H	Alpha-acetolactate decarboxylase	-	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
SRR25158351_k127_1540679_1	273068.TTE2219	1.028e-10	68.0	COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1UHZC@1239|Firmicutes,25E80@186801|Clostridia,42FCR@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
SRR25158351_k127_1547560_26	1218084.BBJK01000006_gene736	2.649e-16	83.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,1K23X@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158351_k127_1547560_6	469383.Cwoe_3722	1.129e-89	316.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4CPIX@84995|Rubrobacteria	84995|Rubrobacteria	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158351_k127_1547560_17	1121087.AUCK01000001_gene2643	1.689e-49	184.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158351_k127_1547560_5	469383.Cwoe_3708	9.618e-91	312.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4CQ5P@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158351_k127_1547560_14	1283299.AUKG01000002_gene4693	3.984e-54	196.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4CQB8@84995|Rubrobacteria	84995|Rubrobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158351_k127_1547560_0	469383.Cwoe_3706	2.876e-168	546.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158351_k127_1547560_21	1380390.JIAT01000010_gene4212	1.5e-30	126.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CQNG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158351_k127_1547560_1	42256.RradSPS_1377	3.067e-149	500.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CPM1@84995|Rubrobacteria	84995|Rubrobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158351_k127_1547560_20	1380390.JIAT01000010_gene4224	6.951e-36	151.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158351_k127_1547560_16	469383.Cwoe_3699	1.395e-50	185.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158351_k127_1547560_11	469383.Cwoe_3698	8.679e-60	212.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1547560_24	1122939.ATUD01000004_gene3791	4.446e-20	97.0	COG1399@1|root,COG1399@2|Bacteria,2HQSM@201174|Actinobacteria,4CSGR@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158351_k127_1547560_28	1238182.C882_3686	1.393e-13	74.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2JTZ3@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158351_k127_1547560_9	1121468.AUBR01000030_gene1220	1.503e-81	284.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,42F74@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158351_k127_1547560_23	42256.RradSPS_1388	2.359e-21	95.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158351_k127_1547560_19	469383.Cwoe_3689	8.406e-40	157.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CPZ4@84995|Rubrobacteria	84995|Rubrobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158351_k127_1547560_7	1122939.ATUD01000004_gene3796	1.145e-85	320.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158351_k127_1547560_8	1121468.AUBR01000030_gene1228	1.168e-82	294.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42ENW@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158351_k127_1547560_2	1121428.DESHY_40031___1	2.107e-148	482.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,2610F@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158351_k127_1547560_22	42256.RradSPS_1394	4.493e-23	102.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CQNJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158351_k127_1547560_29	927704.SELR_14940	5.766e-13	71.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4H5NW@909932|Negativicutes	909932|Negativicutes	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158351_k127_1547560_25	479431.Namu_3134	3.751e-17	89.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4ET25@85013|Frankiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158351_k127_1547560_10	469383.Cwoe_3679	2.68e-81	279.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CPQ4@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158351_k127_1547560_18	469383.Cwoe_3678	1.512e-45	175.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CQ3H@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158351_k127_1547560_15	1122939.ATUD01000004_gene3807	4.65e-51	191.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CQ01@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158351_k127_1547560_27	1161401.ASJA01000002_gene2668	9.364e-16	81.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,43YE8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Uncharacterised protein family UPF0102	MA20_24645	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158351_k127_1547560_4	797302.Halru_2206	1.256e-97	330.0	arCOG06337@1|root,arCOG06337@2157|Archaea,2XTXK@28890|Euryarchaeota,23SF3@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1547560_3	671143.DAMO_3080	1.465e-134	448.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158351_k127_1547560_12	266117.Rxyl_1396	6.96e-59	215.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria	84995|Rubrobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158351_k127_1547560_13	1283299.AUKG01000001_gene2041	1.254e-54	202.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158351_k127_1568592_0	1120973.AQXL01000132_gene2184	6.044e-211	664.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,27852@186823|Alicyclobacillaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158351_k127_1568592_10	1122939.ATUD01000020_gene2162	8.663e-23	104.0	COG0712@1|root,COG0712@2|Bacteria,2HNXP@201174|Actinobacteria,4CQ6B@84995|Rubrobacteria	84995|Rubrobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158351_k127_1568592_9	1122939.ATUD01000020_gene2163	9.21e-25	111.0	COG0711@1|root,COG0711@2|Bacteria,2HR5V@201174|Actinobacteria,4CT1D@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158351_k127_1568592_11	1283299.AUKG01000002_gene3885	1.17e-19	93.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158351_k127_1568592_5	1380390.JIAT01000009_gene346	5.297e-55	212.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CR6B@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase A chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_A
SRR25158351_k127_1568592_3	1380390.JIAT01000009_gene360	8.023e-91	312.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CQIN@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158351_k127_1568592_7	1463895.JODA01000019_gene7328	1.166e-42	169.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158351_k127_1568592_12	469383.Cwoe_0761	1.716e-19	96.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08170	-	M00702	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.23,2.A.1.3.59	-	-	MFS_1
SRR25158351_k127_1568592_4	469383.Cwoe_0761	1.077e-56	218.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08170	-	M00702	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.23,2.A.1.3.59	-	-	MFS_1
SRR25158351_k127_1568592_13	105425.BBPL01000068_gene3555	1.362e-16	84.0	COG2223@1|root,COG2223@2|Bacteria,2I4Q7@201174|Actinobacteria,2NFQ8@228398|Streptacidiphilus	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1568592_1	1089545.KB913037_gene2746	1.631e-156	504.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4DZ2J@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158351_k127_1568592_6	1125863.JAFN01000001_gene1724	5.301e-55	206.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158351_k127_1568592_2	926692.AZYG01000056_gene489	1.138e-106	356.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WA65@53433|Halanaerobiales	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_1568592_8	469383.Cwoe_4636	3.695e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CQSQ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158351_k127_1576476_2	1232410.KI421412_gene337	0.0005504	49.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158351_k127_1576476_1	644282.Deba_1724	0.0001454	46.0	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42W21@68525|delta/epsilon subdivisions,2WRE7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158351_k127_1576476_0	1121946.AUAX01000003_gene1410	2.76e-08	66.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,2HA65@201174|Actinobacteria,4DMVM@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1596109_2	450851.PHZ_c0152	8.956e-147	471.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2KEZF@204458|Caulobacterales	204458|Caulobacterales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158351_k127_1596109_1	1303518.CCALI_00259	1.047e-155	501.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_1596109_0	436114.SYO3AOP1_0248	4.394e-185	594.0	COG1053@1|root,COG1053@2|Bacteria,2G3PJ@200783|Aquificae	200783|Aquificae	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	sdhA	-	1.3.1.6,1.3.5.1,1.3.5.4	ko:K00239,ko:K18556	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R00402,R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158351_k127_1596109_7	1131269.AQVV01000001_gene1358	4.31e-73	258.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158351_k127_1596109_6	330214.NIDE2527	2.297e-78	275.0	COG2048@1|root,COG2048@2|Bacteria,3J175@40117|Nitrospirae	40117|Nitrospirae	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00241,ko:K03389	ko00020,ko00190,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00356,M00357,M00374,M00376,M00563,M00567	R02164,R04540,R11928,R11931,R11943,R11944	RC00011,RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
SRR25158351_k127_1596109_9	1435356.Y013_16455	1.741e-13	79.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria,4FXQY@85025|Nocardiaceae	201174|Actinobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1596109_3	351607.Acel_1448	3.507e-96	325.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2GIV9@201174|Actinobacteria,4EXEH@85013|Frankiales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_1596109_10	469383.Cwoe_4507	3.589e-07	57.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4CQ9D@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_1596109_5	469383.Cwoe_4508	3.65e-83	283.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CS6C@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1596109_8	1128421.JAGA01000002_gene1259	1.459e-32	138.0	COG1525@1|root,COG1680@1|root,COG1525@2|Bacteria,COG1680@2|Bacteria,2NQ3M@2323|unclassified Bacteria	2|Bacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1,3.4.16.4	ko:K01174,ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,Beta-lactamase,SNase
SRR25158351_k127_1596109_4	1380354.JIAN01000006_gene616	3.268e-83	281.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4F21G@85016|Cellulomonadaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3432c	Pyridoxal_deC
SRR25158351_k127_161467_8	469383.Cwoe_5904	3.965e-29	134.0	COG2234@1|root,COG2234@2|Bacteria,2HNS9@201174|Actinobacteria,4CPZX@84995|Rubrobacteria	84995|Rubrobacteria	S	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_161467_0	929712.KI912613_gene547	1.569e-166	537.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4CPJV@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase, family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158351_k127_161467_10	1449068.JMLQ01000001_gene530	1.419e-16	93.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria,4G8IJ@85025|Nocardiaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
SRR25158351_k127_161467_9	1123269.NX02_21170	9.78e-18	95.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales	204457|Sphingomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158351_k127_161467_11	1123274.KB899414_gene3754	5.59e-07	61.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
SRR25158351_k127_161467_2	469383.Cwoe_0979	3.639e-63	237.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158351_k127_161467_4	1380390.JIAT01000009_gene365	3.217e-51	195.0	COG0438@1|root,COG0438@2|Bacteria,2HPUM@201174|Actinobacteria,4CR8J@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158351_k127_161467_6	997346.HMPREF9374_2351	9.274e-31	139.0	COG3307@1|root,COG3307@2|Bacteria,1V5WV@1239|Firmicutes,4HIEW@91061|Bacilli,27B6C@186824|Thermoactinomycetaceae	91061|Bacilli	M	O-Antigen ligase	-	-	-	ko:K16705	-	-	-	-	ko00000	-	-	-	Wzy_C
SRR25158351_k127_161467_1	1329516.JPST01000014_gene495	7.204e-64	239.0	COG0297@1|root,COG0297@2|Bacteria,1UHWI@1239|Firmicutes,4ITQ3@91061|Bacilli,27CNC@186824|Thermoactinomycetaceae	91061|Bacilli	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_161467_3	709986.Deima_0372	5.476e-62	229.0	COG3919@1|root,COG3919@2|Bacteria	2|Bacteria	E	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C
SRR25158351_k127_161467_7	686340.Metal_0328	1.754e-30	139.0	COG0726@1|root,COG0726@2|Bacteria,1R6DC@1224|Proteobacteria,1S7NQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_161467_5	646529.Desaci_4444	3.383e-32	145.0	COG0438@1|root,COG0438@2|Bacteria,1UYBT@1239|Firmicutes,24I1K@186801|Clostridia,260IA@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1618410_3	1219045.BV98_001284	8.545e-05	51.0	2DMP1@1|root,32SS8@2|Bacteria,1NC27@1224|Proteobacteria,2VGQE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SRR25158351_k127_1618410_0	436229.JOEH01000014_gene6189	2.888e-57	216.0	arCOG06766@1|root,2Z87F@2|Bacteria,2IAM6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1618410_1	1122939.ATUD01000002_gene1386	2.09e-31	130.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4CQW7@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158351_k127_1618410_2	469383.Cwoe_2831	1.347e-23	113.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CPP2@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158351_k127_1666036_7	1313172.YM304_40260	5.743e-35	141.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K16137,ko:K22041	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158351_k127_1666036_8	1384484.AEQU_0702	5.93e-33	144.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CVBG@84998|Coriobacteriia	84998|Coriobacteriia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158351_k127_1666036_4	1122939.ATUD01000009_gene3000	6.26e-60	218.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158351_k127_1666036_1	469383.Cwoe_5259	3.203e-181	580.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CQ79@84995|Rubrobacteria	84995|Rubrobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158351_k127_1666036_3	570967.JMLV01000001_gene2756	1.237e-63	228.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,2JR2C@204441|Rhodospirillales	204441|Rhodospirillales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158351_k127_1666036_5	469383.Cwoe_5257	4.222e-56	209.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158351_k127_1666036_6	1118059.CAHC01000001_gene689	6.978e-37	151.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WCMF@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158351_k127_1666036_9	1089549.AZUQ01000001_gene2219	2.811e-17	94.0	COG1503@1|root,COG1503@2|Bacteria,2IJI5@201174|Actinobacteria,4EYIQ@85014|Glycomycetales	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1666036_2	333138.LQ50_00655	2.445e-84	291.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158351_k127_1666036_0	1183438.GKIL_2776	3.096e-181	585.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158351_k127_1672293_3	1121033.AUCF01000003_gene3080	2.734e-17	92.0	COG0697@1|root,COG0697@2|Bacteria,1MY0D@1224|Proteobacteria,2TRTK@28211|Alphaproteobacteria,2JPGG@204441|Rhodospirillales	204441|Rhodospirillales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15269	-	-	-	-	ko00000,ko02000	2.A.7.3.3	-	-	EamA
SRR25158351_k127_1672293_1	909613.UO65_0660	5.182e-103	348.0	COG2271@1|root,COG2271@2|Bacteria,2IAK4@201174|Actinobacteria,4E0RZ@85010|Pseudonocardiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1672293_0	3649.evm.model.supercontig_64.96	1.413e-128	418.0	COG0113@1|root,KOG2794@2759|Eukaryota,37KWI@33090|Viridiplantae,3GENY@35493|Streptophyta,3HR35@3699|Brassicales	35493|Streptophyta	H	Belongs to the ALAD family	HEMB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158351_k127_1672293_2	1122939.ATUD01000002_gene1444	7.469e-71	254.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_1673798_0	479434.Sthe_1523	1.619e-222	700.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi,27XVW@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158351_k127_1673798_16	1380347.JNII01000008_gene4355	5.086e-28	124.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4ESVJ@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158351_k127_1673798_21	395495.Lcho_1873	6.138e-11	68.0	COG0824@1|root,COG2153@1|root,COG0824@2|Bacteria,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,1KJX6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
SRR25158351_k127_1673798_15	1122182.KB903833_gene5326	2.518e-28	126.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4D8Y3@85008|Micromonosporales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158351_k127_1673798_12	1380390.JIAT01000009_gene2018	1.096e-34	136.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158351_k127_1673798_4	1229780.BN381_310061	2.024e-105	358.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,3UWC1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158351_k127_1673798_13	272557.APE_1260	2.252e-32	134.0	COG0491@1|root,arCOG00504@2157|Archaea,2XR9R@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158351_k127_1673798_9	1521187.JPIM01000002_gene3155	2.05e-41	158.0	COG0698@1|root,COG0698@2|Bacteria,2G8SW@200795|Chloroflexi,377K0@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158351_k127_1673798_11	67356.KL575596_gene6601	2.335e-40	159.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria	201174|Actinobacteria	S	Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158351_k127_1673798_6	1283299.AUKG01000002_gene4773	5.602e-88	298.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1673798_10	626939.HMPREF9443_00310	1.387e-40	160.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H2C6@909932|Negativicutes	909932|Negativicutes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158351_k127_1673798_18	1283299.AUKG01000002_gene4665	8.945e-21	102.0	COG3428@1|root,COG3428@2|Bacteria,2HQX2@201174|Actinobacteria,4CSPP@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158351_k127_1673798_8	1110502.TMO_0143	1.107e-52	200.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2TTNQ@28211|Alphaproteobacteria,2JRUT@204441|Rhodospirillales	204441|Rhodospirillales	Q	methionine biosynthesis	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
SRR25158351_k127_1673798_2	1121933.AUHH01000028_gene1890	1.162e-157	506.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4DNSW@85009|Propionibacteriales	201174|Actinobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158351_k127_1673798_1	469383.Cwoe_0711	1.582e-220	691.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CRHN@84995|Rubrobacteria	84995|Rubrobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158351_k127_1673798_22	485913.Krac_0986	6.756e-11	70.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158351_k127_1673798_14	1144325.PMI22_06140	2.068e-30	130.0	COG1309@1|root,COG1309@2|Bacteria,1RAHE@1224|Proteobacteria,1S2WD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,TetR_N
SRR25158351_k127_1673798_19	1231190.NA8A_12550	1.984e-19	94.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_1673798_7	1157640.AQWO01000030_gene1934	3.687e-59	215.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
SRR25158351_k127_1673798_5	326427.Cagg_3077	4.321e-97	348.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi,375PJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158351_k127_1673798_3	1229780.BN381_40028	9.594e-133	439.0	COG3046@1|root,COG3046@2|Bacteria,2GMF6@201174|Actinobacteria,3UX35@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	cry1	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
SRR25158351_k127_1673798_23	865861.AZSU01000004_gene965	0.0006591	45.0	2BBRW@1|root,325A1@2|Bacteria,1URDA@1239|Firmicutes,24WPQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1673798_20	1046724.KB889901_gene3232	2.133e-13	76.0	COG4319@1|root,COG4319@2|Bacteria,1NIZ6@1224|Proteobacteria,1SUX8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158351_k127_1673798_17	933801.Ahos_0756	3.724e-25	114.0	COG0295@1|root,arCOG04173@2157|Archaea,2XQU4@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM CMP dCMP deaminase zinc-binding	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158351_k127_1674223_3	469383.Cwoe_1886	1.489e-66	243.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158351_k127_1674223_6	1229487.AMYW01000039_gene914	1.323e-30	134.0	COG0346@1|root,COG0346@2|Bacteria,4NQAI@976|Bacteroidetes,1I3NI@117743|Flavobacteriia,2NWAJ@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
SRR25158351_k127_1674223_7	469383.Cwoe_1885	2.397e-30	124.0	COG0736@1|root,COG0736@2|Bacteria,2HPF3@201174|Actinobacteria,4CQTC@84995|Rubrobacteria	84995|Rubrobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158351_k127_1674223_0	469383.Cwoe_1884	1.772e-224	711.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CPJN@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158351_k127_1674223_1	1408424.JHYI01000047_gene1633	1.993e-121	405.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,1ZC74@1386|Bacillus	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_1674223_5	469383.Cwoe_1882	1.017e-36	145.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158351_k127_1674223_4	469383.Cwoe_1881	2.124e-61	215.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158351_k127_1674223_2	42256.RradSPS_0697	4.158e-99	325.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CPPY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158351_k127_168935_31	1151117.AJLF01000001_gene1666	4.551e-13	72.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,242SB@183968|Thermococci	183968|Thermococci	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_168935_14	1254432.SCE1572_42625	2.517e-62	230.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2Z0SK@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_168935_19	365528.KB891219_gene1139	4.169e-51	191.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4EVWT@85013|Frankiales	201174|Actinobacteria	M	Bacterial sugar transferase	epsL	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158351_k127_168935_16	469383.Cwoe_3526	8.731e-60	224.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158351_k127_168935_13	1283299.AUKG01000002_gene4915	6.921e-67	248.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158351_k127_168935_22	292459.STH1102	2.831e-42	174.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia	186801|Clostridia	KLT	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN,Polysacc_synt_3,Polysacc_synt_C
SRR25158351_k127_168935_3	929712.KI912613_gene1082	5.996e-152	486.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4CPD2@84995|Rubrobacteria	84995|Rubrobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158351_k127_168935_6	1122182.KB903834_gene5745	5.346e-102	341.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158351_k127_168935_24	868864.Dester_0938	3.413e-38	153.0	COG0805@1|root,COG0805@2|Bacteria,2G41B@200783|Aquificae	200783|Aquificae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158351_k127_168935_34	469383.Cwoe_1849	8.623e-07	56.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158351_k127_168935_33	1121920.AUAU01000005_gene1012	1.047e-09	66.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	aroA	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04092,ko:K04093,ko:K04516,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
SRR25158351_k127_168935_12	1283299.AUKG01000001_gene1774	4.829e-68	237.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158351_k127_168935_29	378753.KRH_21780	3.517e-14	76.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,1W8YJ@1268|Micrococcaceae	201174|Actinobacteria	T	Response regulators are key elements in two-component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_168935_18	663278.Ethha_2790	5.165e-52	196.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158351_k127_168935_8	1283299.AUKG01000001_gene1771	1.762e-89	302.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CQ24@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158351_k127_168935_25	469383.Cwoe_5944	1.719e-35	145.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CQFC@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158351_k127_168935_28	429009.Adeg_2148	5.819e-20	98.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,42G7M@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158351_k127_168935_21	1380390.JIAT01000009_gene1795	2.582e-42	170.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CPXT@84995|Rubrobacteria	84995|Rubrobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158351_k127_168935_26	1380390.JIAT01000009_gene1794	2.065e-29	120.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4CQSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158351_k127_168935_30	649639.Bcell_4330	1.203e-13	76.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,1ZHUH@1386|Bacillus	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158351_k127_168935_32	649638.Trad_0367	4.039e-11	65.0	COG0230@1|root,COG0230@2|Bacteria,1WKP1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158351_k127_168935_27	266117.Rxyl_3217	5.475e-29	128.0	COG1846@1|root,COG2172@1|root,COG1846@2|Bacteria,COG2172@2|Bacteria,2I4BY@201174|Actinobacteria	201174|Actinobacteria	KT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TrmB
SRR25158351_k127_168935_5	1341151.ASZU01000008_gene1348	2.38e-133	444.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,27BH0@186824|Thermoactinomycetaceae	91061|Bacilli	L	Bacterial dnaA protein helix-turn-helix domain	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158351_k127_168935_10	469383.Cwoe_0002	2.116e-86	298.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158351_k127_168935_17	469383.Cwoe_0003	3.107e-53	202.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CQ4U@84995|Rubrobacteria	84995|Rubrobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
SRR25158351_k127_168935_0	469383.Cwoe_0005	7.549e-282	887.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158351_k127_168935_1	649764.HMPREF0762_01217	1.689e-279	882.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CU8E@84998|Coriobacteriia	84998|Coriobacteriia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158351_k127_168935_2	1246995.AFR_22615	1.158e-248	785.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4DM46@85008|Micromonosporales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158351_k127_168935_20	469383.Cwoe_1814	7.622e-50	187.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158351_k127_168935_9	1382356.JQMP01000004_gene282	1.712e-88	302.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,27XRQ@189775|Thermomicrobia	189775|Thermomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158351_k127_168935_23	765420.OSCT_0208	2.556e-39	157.0	COG0764@1|root,COG0764@2|Bacteria,2G8P4@200795|Chloroflexi,375PF@32061|Chloroflexia	32061|Chloroflexia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158351_k127_168935_7	1227352.C173_22787	1.398e-100	340.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,26QJP@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158351_k127_168935_15	500635.MITSMUL_05396	4.589e-60	225.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4H21S@909932|Negativicutes	909932|Negativicutes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158351_k127_168935_11	1200557.JHWV01000001_gene418	1.565e-68	243.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_168935_4	1173022.Cri9333_1767	7.701e-140	458.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1H7C2@1150|Oscillatoriales	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_1699299_7	1380390.JIAT01000009_gene1819	6.198e-30	126.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria,4CQW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158351_k127_1699299_1	469383.Cwoe_5927	1.498e-83	286.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158351_k127_1699299_5	1283299.AUKG01000001_gene1796	7.058e-44	170.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
SRR25158351_k127_1699299_4	272558.10174268	2.542e-51	190.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,1ZFID@1386|Bacillus	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
SRR25158351_k127_1699299_3	1380390.JIAT01000009_gene1822	6.892e-67	241.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158351_k127_1699299_2	1380390.JIAT01000009_gene1823	6.249e-67	240.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158351_k127_1699299_8	264732.Moth_1846	7.258e-05	52.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia,42FB5@68295|Thermoanaerobacterales	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158351_k127_1699299_6	292459.STH819	3.96e-34	147.0	COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,24CGN@186801|Clostridia	186801|Clostridia	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158351_k127_1699299_0	595460.RRSWK_02228	5.136e-115	387.0	COG1060@1|root,COG1060@2|Bacteria,2IX1I@203682|Planctomycetes	203682|Planctomycetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SRR25158351_k127_1706396_10	1246995.AFR_10745	6.878e-62	219.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4DCZ3@85008|Micromonosporales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158351_k127_1706396_13	1214101.BN159_5318	5.641e-41	156.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158351_k127_1706396_4	1380390.JIAT01000001_gene5114	6.713e-112	387.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158351_k127_1706396_8	926550.CLDAP_30680	5.196e-69	249.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158351_k127_1706396_12	401526.TcarDRAFT_0543	7.493e-45	175.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158351_k127_1706396_5	42256.RradSPS_1558	2.532e-87	298.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CPHA@84995|Rubrobacteria	84995|Rubrobacteria	D	ATPases associated with a variety of cellular activities	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158351_k127_1706396_3	469383.Cwoe_4596	6.747e-127	421.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_1706396_0	42256.RradSPS_1561	1.658e-288	910.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CPGC@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158351_k127_1706396_14	42256.RradSPS_1562	1.98e-36	145.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CQU6@84995|Rubrobacteria	84995|Rubrobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158351_k127_1706396_15	1274402.JQAJ01000003_gene731	6.075e-30	130.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,47FBZ@766|Rickettsiales	766|Rickettsiales	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158351_k127_1706396_1	469383.Cwoe_4356	4.007e-256	796.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4CPPC@84995|Rubrobacteria	84995|Rubrobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158351_k127_1706396_7	760568.Desku_3301	2.001e-73	261.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
SRR25158351_k127_1706396_6	1283299.AUKG01000002_gene3900	3.821e-80	280.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158351_k127_1706396_2	469383.Cwoe_4614	7.249e-154	498.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4CPRS@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158351_k127_1706396_11	1283299.AUKG01000002_gene3898	6.919e-59	226.0	COG1316@1|root,COG1316@2|Bacteria,2HJ7K@201174|Actinobacteria,4CPJT@84995|Rubrobacteria	84995|Rubrobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158351_k127_1706396_9	469383.Cwoe_4616	1.872e-65	228.0	COG0624@1|root,COG0624@2|Bacteria,2I9GD@201174|Actinobacteria,4CPM7@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_1711145_6	1262914.BN533_00121	1.251e-38	147.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes	909932|Negativicutes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_1711145_8	1382304.JNIL01000001_gene63	2.819e-30	130.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158351_k127_1711145_0	1150398.JIBJ01000004_gene2813	5.923e-219	714.0	COG0318@1|root,COG0318@2|Bacteria,2HIY1@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
SRR25158351_k127_1711145_16	1121091.AUMP01000021_gene3157	4.585e-05	53.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli	91061|Bacilli	C	COG2010 Cytochrome c, mono- and diheme variants	cccB	-	-	ko:K12263,ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SRR25158351_k127_1711145_13	459495.SPLC1_S041060	2.762e-08	63.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HemolysinCabind
SRR25158351_k127_1711145_7	96561.Dole_0374	2.051e-38	156.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MI23@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
SRR25158351_k127_1711145_1	469383.Cwoe_1866	9.269e-84	284.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158351_k127_1711145_2	929712.KI912613_gene4811	1.533e-65	232.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158351_k127_1711145_14	1120936.KB907221_gene2226	2.434e-05	56.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,4EI2H@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158351_k127_1711145_20	1236501.BAJU01000002_gene391	0.0009021	50.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2JQSF@204441|Rhodospirillales	204441|Rhodospirillales	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158351_k127_1711145_17	1448389.BAVQ01000070_gene2286	5.183e-05	54.0	COG1073@1|root,COG1073@2|Bacteria,2GNCI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158351_k127_1711145_3	742722.HMPREF9463_01000	4.68e-62	224.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CVD5@84998|Coriobacteriia	84998|Coriobacteriia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158351_k127_1711145_15	1050202.KB913024_gene203	3.781e-05	51.0	COG3339@1|root,COG3339@2|Bacteria,2IR8D@201174|Actinobacteria	201174|Actinobacteria	O	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1711145_5	1191523.MROS_0441	1.21e-46	177.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158351_k127_1711145_9	285535.JOEY01000075_gene5964	1.946e-29	123.0	COG1853@1|root,COG1853@2|Bacteria,2GMPH@201174|Actinobacteria	201174|Actinobacteria	K	PFAM flavin reductase domain protein, FMN-binding	-	-	-	ko:K14631	ko01057,ko01130,map01057,map01130	M00779	R05705	RC00126	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavin_Reduct
SRR25158351_k127_1711145_18	1121017.AUFG01000014_gene2011	7.8e-05	52.0	COG1670@1|root,COG1670@2|Bacteria,2GMDB@201174|Actinobacteria,4FG4E@85021|Intrasporangiaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158351_k127_1711145_10	981369.JQMJ01000004_gene6115	9.389e-26	110.0	2C19F@1|root,32ZRH@2|Bacteria,2I872@201174|Actinobacteria,2NJI1@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1711145_12	1380354.JIAN01000006_gene619	4.008e-16	89.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria,4F2YQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158351_k127_1711145_19	861299.J421_1656	0.0005214	50.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158351_k127_1711145_4	350058.Mvan_4623	1.015e-56	208.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,234PI@1762|Mycobacteriaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1711145_11	1298863.AUEP01000013_gene4082	3.523e-18	87.0	2C6FT@1|root,334HA@2|Bacteria,2HCTI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1738036_13	491952.Mar181_3031	5.883e-15	78.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XMCR@135619|Oceanospirillales	135619|Oceanospirillales	J	there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158351_k127_1738036_12	1387197.AWGA01000005_gene1383	2.923e-26	109.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158351_k127_1738036_14	710687.KI912270_gene1997	7.15e-12	76.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,232UJ@1762|Mycobacteriaceae	201174|Actinobacteria	H	Methyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158351_k127_1738036_6	929712.KI912613_gene4260	9.249e-80	285.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4CPIS@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_1738036_2	1283299.AUKG01000002_gene4648	7.538e-123	406.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria,4CPFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158351_k127_1738036_8	469383.Cwoe_3737	9.567e-68	244.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158351_k127_1738036_3	517418.Ctha_0517	5.569e-117	386.0	COG0180@1|root,COG0180@2|Bacteria,1FE4Z@1090|Chlorobi	1090|Chlorobi	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158351_k127_1738036_7	1283299.AUKG01000002_gene4974	3.942e-74	259.0	COG1073@1|root,COG1073@2|Bacteria,2I3YE@201174|Actinobacteria,4CRF0@84995|Rubrobacteria	84995|Rubrobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_1738036_5	582515.KR51_00016080	2.125e-100	344.0	COG0128@1|root,COG0128@2|Bacteria,1G1F9@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158351_k127_1738036_10	1121927.GOHSU_02_01580	5.468e-50	187.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4GCWB@85026|Gordoniaceae	201174|Actinobacteria	F	Cytidylate kinase	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158351_k127_1738036_11	1033740.CAEW01000008_gene1870	2.394e-34	144.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,26DU4@186818|Planococcaceae	91061|Bacilli	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158351_k127_1738036_4	1283299.AUKG01000002_gene4652	8.36e-111	377.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CPBT@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158351_k127_1738036_9	1075090.GOAMR_40_01490	5.83e-62	226.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4GFNV@85026|Gordoniaceae	201174|Actinobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158351_k127_1738036_0	1123511.KB905853_gene3690	1.093e-157	512.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158351_k127_1738036_1	469383.Cwoe_3727	1.78e-140	473.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4CPGM@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158351_k127_1738036_15	706439.HMPREF9057_00236	8.764e-12	70.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4D3IX@85005|Actinomycetales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_1758922_1	871968.DESME_12345	1.366e-81	287.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_1758922_0	469383.Cwoe_3770	1.202e-85	301.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CPNI@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158351_k127_1779019_4	929712.KI912613_gene3400	4.965e-123	428.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CPG8@84995|Rubrobacteria	84995|Rubrobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_1779019_7	1122939.ATUD01000005_gene2596	1.12e-106	366.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CPRI@84995|Rubrobacteria	84995|Rubrobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158351_k127_1779019_17	469383.Cwoe_3011	2.297e-54	207.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CPTU@84995|Rubrobacteria	84995|Rubrobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158351_k127_1779019_3	42256.RradSPS_2180	7.442e-135	449.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_1779019_2	479434.Sthe_1187	7.801e-144	479.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,27Z0P@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_1779019_11	477974.Daud_1056	1.768e-83	296.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRR25158351_k127_1779019_10	1146883.BLASA_1045	2.017e-92	318.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,4ERFU@85013|Frankiales	201174|Actinobacteria	P	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
SRR25158351_k127_1779019_5	867903.ThesuDRAFT_02038	2.468e-115	390.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,249NK@186801|Clostridia,3WCQM@538999|Clostridiales incertae sedis	186801|Clostridia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158351_k127_1779019_12	316274.Haur_3938	1.338e-73	256.0	COG1940@1|root,COG1940@2|Bacteria,2G7NH@200795|Chloroflexi,376TI@32061|Chloroflexia	32061|Chloroflexia	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158351_k127_1779019_18	469383.Cwoe_3489	1.843e-53	194.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CQ53@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158351_k127_1779019_15	469383.Cwoe_3490	7.134e-61	219.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158351_k127_1779019_19	1120950.KB892707_gene5033	1.359e-35	140.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DR1A@85009|Propionibacteriales	201174|Actinobacteria	T	zinc-ribbon domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158351_k127_1779019_23	1122939.ATUD01000008_gene2538	2.542e-12	77.0	COG0558@1|root,COG0558@2|Bacteria,2HGA5@201174|Actinobacteria,4CR84@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_1779019_22	662479.C440_15279	3.038e-13	72.0	arCOG04557@1|root,arCOG04557@2157|Archaea,2XZYI@28890|Euryarchaeota,23XGW@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1779019_0	469383.Cwoe_3494	1.62e-193	623.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158351_k127_1779019_1	926554.KI912625_gene702	1.541e-161	518.0	COG0821@1|root,COG0821@2|Bacteria,1WJ94@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158351_k127_1779019_14	1122939.ATUD01000019_gene1552	6.136e-61	225.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158351_k127_1779019_8	469383.Cwoe_3510	4.397e-102	351.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CPQ0@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158351_k127_1779019_20	134676.ACPL_3239	1.586e-33	142.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	4.6.1.1	ko:K01768,ko:K17763	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	EAL,GAF,GAF_2,GAF_3,Guanylate_cyc,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,STAS,dCache_1
SRR25158351_k127_1779019_9	1124780.ANNU01000019_gene1715	3.87e-93	319.0	COG1363@1|root,COG1363@2|Bacteria,4NIW2@976|Bacteroidetes,47JPS@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158351_k127_1779019_6	1056816.JAFQ01000004_gene4655	5.161e-114	382.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4FVXU@85025|Nocardiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
SRR25158351_k127_1779019_16	1122939.ATUD01000019_gene1550	1.381e-55	209.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CQ05@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158351_k127_1779019_13	929712.KI912613_gene3909	2.381e-63	223.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158351_k127_1786217_4	634498.mru_0836	2.453e-06	53.0	arCOG08007@1|root,arCOG08007@2157|Archaea,2Y5WI@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1786217_0	67373.JOBF01000024_gene6794	1.286e-80	284.0	COG0654@1|root,COG0654@2|Bacteria,2GNA8@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.10	ko:K19189	ko00760,ko01120,map00760,map01120	-	R04130	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8
SRR25158351_k127_1786217_2	1385515.N791_12110	1.656e-32	132.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria,1X6ZX@135614|Xanthomonadales	135614|Xanthomonadales	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_1786217_5	446471.Xcel_1638	0.0005593	49.0	COG2345@1|root,COG2345@2|Bacteria,2HJIP@201174|Actinobacteria,4F5UY@85017|Promicromonosporaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1786217_3	1231185.BAMP01000024_gene2577	2.113e-20	100.0	2E3RQ@1|root,32YPC@2|Bacteria,1N676@1224|Proteobacteria,2UDYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1786217_1	1229780.BN381_70131	2.453e-38	156.0	COG2346@1|root,COG2346@2|Bacteria,2IJM0@201174|Actinobacteria	201174|Actinobacteria	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	-
SRR25158351_k127_1786986_1	270374.MELB17_23125	1.066e-94	316.0	COG1335@1|root,COG1335@2|Bacteria,1N48X@1224|Proteobacteria,1S00N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Amidases related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158351_k127_1786986_0	221288.JH992901_gene1078	7.109e-216	703.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JHD5@1189|Stigonemataceae	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158351_k127_1786986_2	221288.JH992901_gene1075	8.34e-93	320.0	COG4191@1|root,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria,1JH5H@1189|Stigonemataceae	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
SRR25158351_k127_1786986_3	1439940.BAY1663_04893	1.358e-29	133.0	COG2203@1|root,COG3920@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SRR25158351_k127_1801662_6	1123072.AUDH01000005_gene1674	1.479e-25	114.0	COG4106@1|root,COG4106@2|Bacteria,1QVY9@1224|Proteobacteria,2U6ST@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_1801662_5	1193181.BN10_760037	3.232e-56	199.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4FGQ0@85021|Intrasporangiaceae	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158351_k127_1801662_4	1380390.JIAT01000011_gene2583	3.519e-63	220.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CQ77@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158351_k127_1801662_0	1121472.AQWN01000016_gene460	4.635e-305	949.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2600F@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_1801662_2	748247.AZKH_4544	6.999e-100	361.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV2U@206389|Rhodocyclales	206389|Rhodocyclales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_7,PAS_8,PAS_9
SRR25158351_k127_1801662_7	266940.Krad_2083	1.06e-17	90.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_1801662_1	266117.Rxyl_2375	1.261e-182	604.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4CU1R@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
SRR25158351_k127_1801662_3	864565.HMPREF0379_0433	8.671e-73	246.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25QC9@186804|Peptostreptococcaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158351_k127_1805006_9	266117.Rxyl_0824	3.456e-47	178.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria,4CQPT@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
SRR25158351_k127_1805006_2	1380390.JIAT01000001_gene5111	4.912e-126	425.0	COG1164@1|root,COG1164@2|Bacteria,2IGPX@201174|Actinobacteria,4CPUP@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158351_k127_1805006_7	1095767.CAHD01000143_gene2236	1.722e-56	207.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4F0J2@85016|Cellulomonadaceae	201174|Actinobacteria	S	SMART phosphoesterase PHP domain protein	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158351_k127_1805006_6	42256.RradSPS_0878	1.78e-58	216.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4CTDY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158351_k127_1805006_5	562970.Btus_0193	8.48e-76	264.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,277XK@186823|Alicyclobacillaceae	91061|Bacilli	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158351_k127_1805006_12	1298593.TOL_2649	3.71e-23	104.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XKIR@135619|Oceanospirillales	135619|Oceanospirillales	J	Translation initiation factor	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR25158351_k127_1805006_3	1283299.AUKG01000001_gene1271	4.324e-115	396.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CPTE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HD,Ppx-GppA
SRR25158351_k127_1805006_13	1394178.AWOO02000005_gene3538	1.167e-21	105.0	COG0317@1|root,COG0317@2|Bacteria,2IP1T@201174|Actinobacteria,4EP7W@85012|Streptosporangiales	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158351_k127_1805006_14	4572.TRIUR3_12898-P1	7.148e-11	68.0	COG0589@1|root,2RXWD@2759|Eukaryota,37UWB@33090|Viridiplantae,3GI2N@35493|Streptophyta,3KZ66@4447|Liliopsida,3IH6Z@38820|Poales	35493|Streptophyta	T	Universal stress protein A-like protein	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_1805006_8	1279019.ARQK01000047_gene1012	2.386e-54	213.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales	135613|Chromatiales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158351_k127_1805006_0	469383.Cwoe_4548	3.486e-156	514.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CPKI@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158351_k127_1805006_4	469383.Cwoe_5554	1.187e-113	378.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4CR2R@84995|Rubrobacteria	84995|Rubrobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158351_k127_1805006_11	1121946.AUAX01000014_gene1260	2.75e-25	118.0	COG1309@1|root,COG1309@2|Bacteria,2GP3D@201174|Actinobacteria,4DD5T@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158351_k127_1805006_10	390989.JOEG01000021_gene2634	3.095e-28	128.0	COG0477@1|root,COG0477@2|Bacteria,2I38S@201174|Actinobacteria,4DDCQ@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1805006_1	469383.Cwoe_3833	5.163e-156	498.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4CS2X@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158351_k127_1807064_8	1323361.JPOC01000007_gene427	4.544e-21	95.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4G1CD@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1807064_13	1184607.AUCHE_17_00080	0.0007267	52.0	COG1506@1|root,COG1506@2|Bacteria,2HFP5@201174|Actinobacteria,4F7QX@85018|Dermatophilaceae	201174|Actinobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158351_k127_1807064_1	1041147.AUFB01000007_gene403	2.572e-110	374.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,2TV47@28211|Alphaproteobacteria,4B9ZF@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158351_k127_1807064_10	313612.L8106_26857	1.482e-17	95.0	COG1357@1|root,COG1357@2|Bacteria,1G1VX@1117|Cyanobacteria,1H90B@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158351_k127_1807064_9	546271.Selsp_0779	1.001e-17	90.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,4H4IK@909932|Negativicutes	909932|Negativicutes	K	PFAM Transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158351_k127_1807064_2	309799.DICTH_1169	9.395e-109	369.0	COG0008@1|root,COG0008@2|Bacteria	2|Bacteria	J	glutamate-tRNA ligase activity	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158351_k127_1807064_3	929712.KI912613_gene3976	1.097e-62	243.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CP9J@84995|Rubrobacteria	84995|Rubrobacteria	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158351_k127_1807064_0	1380390.JIAT01000009_gene1462	9.63e-154	494.0	COG0667@1|root,COG0667@2|Bacteria,2HQ4U@201174|Actinobacteria,4CRMQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_1807064_7	1121468.AUBR01000019_gene2640	3.783e-22	101.0	COG1695@1|root,COG1695@2|Bacteria,1V7D3@1239|Firmicutes,24ME9@186801|Clostridia,42HAY@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158351_k127_1807064_11	675635.Psed_6414	1.119e-12	74.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158351_k127_1807064_4	675635.Psed_6414	4.346e-60	226.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158351_k127_1807064_5	1282876.BAOK01000001_gene1598	6.733e-60	218.0	COG2267@1|root,COG2267@2|Bacteria,1QWJZ@1224|Proteobacteria,2TUZE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4
SRR25158351_k127_1807064_14	1089551.KE386572_gene1056	0.0007598	50.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2TT27@28211|Alphaproteobacteria,4BS8X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1807064_6	1386089.N865_05305	3.449e-47	183.0	COG0300@1|root,COG0300@2|Bacteria,2HJGE@201174|Actinobacteria,4FGMX@85021|Intrasporangiaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1807064_12	1089453.GOSPT_015_00120	9.11e-08	59.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158351_k127_180854_2	485913.Krac_6983	6.946e-26	110.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	AhpC-TSA,MauE
SRR25158351_k127_180854_1	219305.MCAG_02747	2.148e-26	124.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,4D8V7@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158351_k127_180854_0	1380393.JHVP01000003_gene1268	5.902e-119	408.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158351_k127_180854_5	5465.ENH81268	1.783e-06	52.0	COG0596@1|root,2QPPY@2759|Eukaryota,38J2J@33154|Opisthokonta,3NZP5@4751|Fungi,3QUN9@4890|Ascomycota,21A6B@147550|Sordariomycetes,1EZSW@1028384|Glomerellales	4751|Fungi	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158351_k127_180854_4	1122182.KB903836_gene4784	1.569e-06	58.0	2B2VH@1|root,31VG1@2|Bacteria,2HWUF@201174|Actinobacteria,4DKDF@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_180854_3	1172179.AUKV01000005_gene5865	1.7e-24	113.0	COG3212@1|root,COG3212@2|Bacteria,2IF4I@201174|Actinobacteria	201174|Actinobacteria	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1824136_1	1240349.ANGC01000051_gene4110	4.765e-43	166.0	COG1028@1|root,COG1028@2|Bacteria,2IFUD@201174|Actinobacteria,4FYUB@85025|Nocardiaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ywfD	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_1824136_2	1114856.C496_20455	8.26e-40	164.0	COG1233@1|root,arCOG01523@2157|Archaea,2XTVK@28890|Euryarchaeota,23S90@183963|Halobacteria	183963|Halobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	crtI3	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_1824136_0	861299.J421_3439	1.639e-63	237.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158351_k127_1824136_5	627192.SLG_30750	2.098e-07	61.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2K6WZ@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158351_k127_1824136_3	1380390.JIAT01000010_gene4272	1.316e-28	123.0	2BR5U@1|root,32K3Y@2|Bacteria,2HP6A@201174|Actinobacteria,4CQI3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1826453_1	469383.Cwoe_3174	4.547e-130	426.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_1826453_5	369723.Strop_3177	2.878e-19	96.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4D9Z7@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1826453_4	926550.CLDAP_18620	2.133e-19	92.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158351_k127_1826453_2	886293.Sinac_1135	2.106e-93	318.0	COG1060@1|root,COG1060@2|Bacteria,2IXUS@203682|Planctomycetes	203682|Planctomycetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
SRR25158351_k127_1826453_3	1283299.AUKG01000001_gene3163	3.86e-39	153.0	COG4293@1|root,COG4293@2|Bacteria,2IG98@201174|Actinobacteria,4CQEX@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158351_k127_1826453_6	1380390.JIAT01000010_gene3606	1.353e-07	59.0	2B8EI@1|root,321PH@2|Bacteria,2HP5J@201174|Actinobacteria,4CQHJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1826453_0	316274.Haur_0133	6.382e-148	476.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_1827468_2	1122939.ATUD01000001_gene372	9.65e-26	109.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158351_k127_1827468_0	469383.Cwoe_1767	3.392e-51	199.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158351_k127_1827468_8	1089552.KI911559_gene1410	3.064e-05	52.0	COG0607@1|root,COG0607@2|Bacteria,1N2R7@1224|Proteobacteria,2U9G7@28211|Alphaproteobacteria,2JU8N@204441|Rhodospirillales	204441|Rhodospirillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158351_k127_1827468_4	1392489.JPOL01000002_gene655	6.04e-18	91.0	2BD06@1|root,326MC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1827468_1	1038869.AXAN01000004_gene1161	9.163e-49	185.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VMHC@28216|Betaproteobacteria,1K31U@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_1827468_5	1123258.AQXZ01000017_gene4041	1.784e-17	91.0	2AYGA@1|root,31QJK@2|Bacteria,2IS7K@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158351_k127_1827468_6	316274.Haur_4510	6.615e-11	72.0	COG0454@1|root,COG0456@2|Bacteria,2GADP@200795|Chloroflexi,375N1@32061|Chloroflexia	32061|Chloroflexia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1827468_7	1382306.JNIM01000001_gene144	6.164e-06	56.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158351_k127_1844637_1	391625.PPSIR1_21414	1.556e-50	209.0	COG0553@1|root,COG0553@2|Bacteria,1MXQH@1224|Proteobacteria,43CNE@68525|delta/epsilon subdivisions,2X7VQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KL	methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1844637_2	1166948.JPZL01000002_gene1858	7.165e-09	68.0	COG0454@1|root,COG0503@1|root,COG3087@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG3087@2|Bacteria,1R2FE@1224|Proteobacteria	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1844637_0	1244869.H261_03393	1.653e-66	239.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2TVMB@28211|Alphaproteobacteria,2JS1E@204441|Rhodospirillales	204441|Rhodospirillales	S	COG4422 Bacteriophage protein gp37	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158351_k127_1845569_3	929506.CbC4_2468	3.658e-33	142.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,36FW2@31979|Clostridiaceae	186801|Clostridia	M	NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
SRR25158351_k127_1845569_2	1007104.SUS17_2373	5.086e-55	198.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2K3VX@204457|Sphingomonadales	204457|Sphingomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158351_k127_1845569_5	1033730.CAHG01000008_gene3077	1.788e-07	62.0	COG3325@1|root,COG3325@2|Bacteria,2IGIW@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1845569_0	1380390.JIAT01000014_gene6079	6.412e-109	371.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CQTJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158351_k127_1845569_1	469383.Cwoe_1028	1.27e-85	296.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CP9P@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158351_k127_1845569_4	1449126.JQKL01000011_gene3592	1.881e-11	66.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,267N9@186813|unclassified Clostridiales	186801|Clostridia	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158351_k127_185390_7	1144275.COCOR_06778	2.047e-95	334.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1R8BD@1224|Proteobacteria,43AIE@68525|delta/epsilon subdivisions,2X5YP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
SRR25158351_k127_185390_13	555778.Hneap_0125	6.387e-26	112.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158351_k127_185390_15	685727.REQ_39240	1.551e-22	107.0	2EEE7@1|root,33888@2|Bacteria,2IMP5@201174|Actinobacteria,4G0SV@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_185390_16	1172185.KB911519_gene3799	7.971e-17	87.0	COG1714@1|root,COG1714@2|Bacteria,2IN6K@201174|Actinobacteria,4G1GS@85025|Nocardiaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158351_k127_185390_8	479434.Sthe_2745	1.075e-79	273.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158351_k127_185390_9	298653.Franean1_4877	3.088e-54	201.0	COG0500@1|root,COG0500@2|Bacteria,2I5UW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_185390_1	234267.Acid_7210	7.002e-165	524.0	COG0500@1|root,COG2226@2|Bacteria,3Y6R8@57723|Acidobacteria	57723|Acidobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158351_k127_185390_2	469383.Cwoe_2964	4.084e-162	537.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158351_k127_185390_3	512565.AMIS_27770	1.506e-119	402.0	COG1502@1|root,COG1502@2|Bacteria,2H9IE@201174|Actinobacteria	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158351_k127_185390_18	465541.ATCJ01000005_gene5556	9.931e-08	59.0	2ATIE@1|root,31J2A@2|Bacteria,2IISG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_185390_6	1298863.AUEP01000011_gene510	1.761e-98	340.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158351_k127_185390_10	1380390.JIAT01000011_gene2334	4.184e-51	198.0	28MY8@1|root,32YD0@2|Bacteria,2HR9A@201174|Actinobacteria,4CT5U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_185390_0	216594.MMAR_0936	0.0	1077.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,23C6I@1762|Mycobacteriaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_185390_11	216594.MMAR_0936	1.375e-42	160.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,23C6I@1762|Mycobacteriaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_185390_14	1120983.KB894572_gene2981	1.27e-23	109.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2V7H9@28211|Alphaproteobacteria,1JQ6N@119043|Rhodobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158351_k127_185390_12	1168059.KB899087_gene3524	1.394e-30	128.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,3F0B4@335928|Xanthobacteraceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158351_k127_185390_5	1242864.D187_006843	2.343e-108	362.0	COG2124@1|root,COG3239@1|root,COG2124@2|Bacteria,COG3239@2|Bacteria,1PP7Y@1224|Proteobacteria,42YWN@68525|delta/epsilon subdivisions,2WUKG@28221|Deltaproteobacteria,2YYFI@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158351_k127_185390_17	216594.MMAR_4436	2.677e-16	87.0	2B2M4@1|root,31V6I@2|Bacteria,2GV2T@201174|Actinobacteria,23DZT@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_185390_4	246197.MXAN_6505	4.857e-110	377.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2YX1N@29|Myxococcales	28221|Deltaproteobacteria	U	Sulfate permease	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158351_k127_185390_19	1123487.KB892835_gene3425	2.134e-05	52.0	292BS@1|root,2ZPW7@2|Bacteria,1REGA@1224|Proteobacteria,2VTQU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_185756_1	1121106.JQKB01000094_gene3969	3.209e-10	68.0	COG2730@1|root,COG2730@2|Bacteria,1R2DY@1224|Proteobacteria	1224|Proteobacteria	G	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
SRR25158351_k127_185756_0	1070319.CAGGBEG34_380012	5.69e-16	88.0	2BVDW@1|root,32QTU@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR25158351_k127_185756_2	68223.JNZY01000054_gene421	0.0006531	51.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158351_k127_1860110_12	478801.Ksed_26230	1.346e-06	56.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,1ZWQF@145357|Dermacoccaceae	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158351_k127_1860110_8	1205910.B005_3272	4.718e-39	154.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria,4EHB5@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158351_k127_1860110_6	1089552.KI911559_gene1300	4.623e-57	211.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,2TUNH@28211|Alphaproteobacteria,2JRQ5@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158351_k127_1860110_1	1122939.ATUD01000005_gene2772	7.893e-110	368.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4CP6Z@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158351_k127_1860110_2	1906.SFRA_16800	1.838e-89	310.0	COG2807@1|root,COG2807@2|Bacteria,2I37C@201174|Actinobacteria	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1860110_13	864069.MicloDRAFT_00019160	3.879e-06	58.0	COG4689@1|root,COG4689@2|Bacteria,1N4IP@1224|Proteobacteria,2TTZX@28211|Alphaproteobacteria,1JU9E@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRR25158351_k127_1860110_11	438753.AZC_0288	2.289e-07	62.0	COG4689@1|root,COG4689@2|Bacteria,1N4IP@1224|Proteobacteria,2TTZX@28211|Alphaproteobacteria,3EZ66@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide	adc	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRR25158351_k127_1860110_7	1134413.ANNK01000143_gene3067	1.731e-47	184.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HB6Q@91061|Bacilli,1ZESG@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
SRR25158351_k127_1860110_3	1382306.JNIM01000001_gene1897	1.734e-82	284.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158351_k127_1860110_10	1380390.JIAT01000010_gene3612	9.422e-27	118.0	COG1920@1|root,COG1920@2|Bacteria,2HNVD@201174|Actinobacteria,4CQ43@84995|Rubrobacteria	84995|Rubrobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158351_k127_1860110_5	266117.Rxyl_0961	5.667e-59	222.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158351_k127_1860110_9	91464.S7335_5420	7.609e-27	119.0	COG0569@1|root,COG0569@2|Bacteria,1G7JT@1117|Cyanobacteria	1117|Cyanobacteria	P	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C
SRR25158351_k127_1860110_0	42256.RradSPS_0884	2.744e-145	482.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4CPHP@84995|Rubrobacteria	84995|Rubrobacteria	H	Elongator protein 3 MiaB NifB	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158351_k127_1860110_4	525904.Tter_2623	8.236e-80	271.0	COG1060@1|root,COG1060@2|Bacteria,2NP8W@2323|unclassified Bacteria	2|Bacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	fbiC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,Radical_SAM
SRR25158351_k127_1872000_0	471852.Tcur_1612	3.382e-100	342.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4EGE8@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158351_k127_1872000_1	1280380.KR100_02535	1.276e-82	286.0	COG0039@1|root,COG0039@2|Bacteria,1G1VJ@1117|Cyanobacteria,1H01Q@1129|Synechococcus	1117|Cyanobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158351_k127_1872000_5	1254432.SCE1572_16710	6.56e-08	61.0	COG0500@1|root,COG2226@2|Bacteria,1QXUA@1224|Proteobacteria,42QNQ@68525|delta/epsilon subdivisions,2WMN4@28221|Deltaproteobacteria,2Z09Z@29|Myxococcales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_1872000_4	1133849.O3I_000355	1.565e-21	104.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,4FVD7@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_1872000_2	501479.ACNW01000103_gene687	1.653e-33	130.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,2TURU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	homocysteine	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
SRR25158351_k127_1872000_3	1229172.JQFA01000004_gene1019	7.188e-29	119.0	COG2040@1|root,COG2040@2|Bacteria,1G1ZI@1117|Cyanobacteria	1117|Cyanobacteria	H	Homocysteine s-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
SRR25158351_k127_1879738_0	1223523.H340_17804	0.0	1043.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158351_k127_1879738_8	543632.JOJL01000010_gene7117	7.023e-19	90.0	COG4102@1|root,COG4102@2|Bacteria,2GJWB@201174|Actinobacteria,4D8D0@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,TAT_signal
SRR25158351_k127_1879738_11	1146883.BLASA_3619	1.56e-05	51.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158351_k127_1879738_2	469383.Cwoe_2667	5.541e-80	273.0	COG4221@1|root,COG4221@2|Bacteria,2IAVE@201174|Actinobacteria,4CR7Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1879738_4	1123060.JONP01000012_gene2812	1.667e-60	220.0	COG2514@1|root,COG2514@2|Bacteria,1PNKQ@1224|Proteobacteria,2VAA8@28211|Alphaproteobacteria,2JY35@204441|Rhodospirillales	204441|Rhodospirillales	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1879738_6	1380390.JIAT01000009_gene1922	4.814e-45	173.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4CQI6@84995|Rubrobacteria	84995|Rubrobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158351_k127_1879738_7	1380390.JIAT01000009_gene1097	8.466e-33	137.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158351_k127_1879738_5	390989.JOEG01000018_gene3640	3.45e-49	182.0	COG1309@1|root,COG1309@2|Bacteria,2GRIJ@201174|Actinobacteria,4DDQA@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1879738_10	1187848.AJYQ01000110_gene418	5.665e-07	55.0	2CAAY@1|root,32RR1@2|Bacteria,1P2IE@1224|Proteobacteria,1SR7R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1879738_1	710111.FraQA3DRAFT_4615	1.356e-118	385.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4EUJK@85013|Frankiales	201174|Actinobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158351_k127_1879738_9	1382356.JQMP01000001_gene1260	5.371e-18	88.0	COG0346@1|root,COG0346@2|Bacteria,2G9U4@200795|Chloroflexi,27Z6P@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1879738_3	1297742.A176_06066	1.872e-73	256.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,42RN7@68525|delta/epsilon subdivisions,2WNNX@28221|Deltaproteobacteria,2Z317@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.14,1.2.1.46	ko:K00008,ko:K00148,ko:K18369	ko00040,ko00051,ko00625,ko00640,ko00680,ko01100,ko01120,ko01200,map00040,map00051,map00625,map00640,map00680,map01100,map01120,map01200	M00014	R00604,R00875,R01896,R10703	RC00085,RC00102,RC00188,RC00545	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_188402_0	1122604.JONR01000011_gene3686	1.079e-105	350.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,1RWBC@1236|Gammaproteobacteria,1X339@135614|Xanthomonadales	135614|Xanthomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158351_k127_188402_2	1380390.JIAT01000011_gene2412	4.514e-35	144.0	COG1584@1|root,COG1584@2|Bacteria,2IMDT@201174|Actinobacteria,4CRAZ@84995|Rubrobacteria	84995|Rubrobacteria	S	GPR1/FUN34/yaaH family	-	-	-	-	-	-	-	-	-	-	-	-	Grp1_Fun34_YaaH
SRR25158351_k127_188402_5	309807.SRU_2537	5.735e-05	51.0	COG0640@1|root,COG0640@2|Bacteria,4PEU3@976|Bacteroidetes,1FJM9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158351_k127_188402_3	1120958.AULD01000009_gene793	2.042e-23	104.0	2E6D0@1|root,3310N@2|Bacteria,2GQP8@201174|Actinobacteria,4FQ3B@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
SRR25158351_k127_188402_1	390989.JOEG01000001_gene4885	1.164e-73	256.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4DAUW@85008|Micromonosporales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_188402_4	1163617.SCD_n00933	2.775e-17	88.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VSR6@28216|Betaproteobacteria	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_1885049_2	1042156.CXIVA_02780	2.983e-89	302.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,36EBV@31979|Clostridiaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
SRR25158351_k127_1885049_7	1283299.AUKG01000002_gene4911	1.965e-60	217.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158351_k127_1885049_8	1121468.AUBR01000017_gene2363	5.168e-54	198.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,42G87@68295|Thermoanaerobacterales	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158351_k127_1885049_5	485916.Dtox_0754	2.446e-64	226.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,261MD@186807|Peptococcaceae	186801|Clostridia	E	PFAM Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158351_k127_1885049_1	469383.Cwoe_3531	1.328e-90	316.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CP7G@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158351_k127_1885049_4	1283299.AUKG01000002_gene4907	2.394e-65	230.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CPQH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
SRR25158351_k127_1885049_6	1122939.ATUD01000019_gene1529	2.249e-62	232.0	COG3705@1|root,COG3705@2|Bacteria,2I6IJ@201174|Actinobacteria,4CQ6U@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidyl-tRNA synthetase	-	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158351_k127_1885049_0	469383.Cwoe_3534	2.106e-165	532.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158351_k127_1885049_3	309801.trd_0391	1.501e-86	302.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158351_k127_1885049_9	204669.Acid345_3258	1.401e-17	93.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158351_k127_1885049_10	1077972.ARGLB_012_00120	2.447e-05	55.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_1885049_11	68570.DC74_4749	0.0001781	50.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_1931502_16	102129.Lepto7375DRAFT_2637	1.864e-09	70.0	COG2706@1|root,COG5276@1|root,COG2706@2|Bacteria,COG5276@2|Bacteria,1GQNB@1117|Cyanobacteria	1117|Cyanobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,DUF4347,Lactonase
SRR25158351_k127_1931502_17	1449347.JQLN01000006_gene2876	1.917e-09	70.0	COG1874@1|root,COG5434@1|root,COG1874@2|Bacteria,COG5434@2|Bacteria,2GKCR@201174|Actinobacteria,2M2H6@2063|Kitasatospora	201174|Actinobacteria	M	to Mycodextranase precursor in Streptomyces sp. J-13-3 (Q93R89)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CARDB,DUF1573,F5_F8_type_C,Pectate_lyase_3
SRR25158351_k127_1931502_12	326427.Cagg_2410	1.626e-22	108.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi,377CS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_1931502_10	28042.GU90_18315	8.648e-31	131.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4E2R5@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_1931502_3	290397.Adeh_2624	3.92e-68	250.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158351_k127_1931502_14	469383.Cwoe_5512	5.099e-17	96.0	2AX0P@1|root,31NYQ@2|Bacteria,2HPNT@201174|Actinobacteria,4CR19@84995|Rubrobacteria	84995|Rubrobacteria	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158351_k127_1931502_8	1487953.JMKF01000050_gene2008	1.012e-33	137.0	COG0681@1|root,COG0681@2|Bacteria,1G54H@1117|Cyanobacteria,1H8FZ@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB2	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158351_k127_1931502_4	929712.KI912613_gene3852	1.777e-48	198.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CRG8@84995|Rubrobacteria	84995|Rubrobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,MASE1
SRR25158351_k127_1931502_5	1235835.C814_02108	3.747e-47	176.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158351_k127_1931502_0	469383.Cwoe_5426	5.794e-282	897.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158351_k127_1931502_9	360911.EAT1b_2176	1.045e-31	133.0	COG0457@1|root,COG0457@2|Bacteria,1UJRM@1239|Firmicutes,4ITEJ@91061|Bacilli	91061|Bacilli	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
SRR25158351_k127_1931502_7	1108045.GORHZ_227_00210	4.08e-44	168.0	COG2095@1|root,COG2095@2|Bacteria	2|Bacteria	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158351_k127_1931502_1	469383.Cwoe_0876	3.494e-154	509.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4CQWK@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1931502_15	134676.ACPL_1419	2.313e-13	81.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807,DUF4097
SRR25158351_k127_1931502_19	1121926.AXWO01000004_gene1015	0.000294	53.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4EZQ0@85014|Glycomycetales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158351_k127_1931502_11	262724.TT_P0164	3.366e-28	129.0	COG1595@1|root,COG1595@2|Bacteria,1WJ7G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158351_k127_1931502_13	222534.KB893739_gene1415	2.619e-20	103.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4ET99@85013|Frankiales	201174|Actinobacteria	CO	Alkyl hydroperoxide reductase Thiol specific antioxidant	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158351_k127_1931502_6	1122132.AQYH01000003_gene2947	1.394e-44	170.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,4BARZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Cytochrome c biogenesis protein	soxV	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158351_k127_1931502_2	324602.Caur_0549	3.297e-106	357.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
SRR25158351_k127_1931502_18	1437608.BBIA_0677	0.000228	46.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CYV8@85004|Bifidobacteriales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158351_k127_1931510_2	991905.SL003B_3473	1.421e-27	115.0	COG2010@1|root,COG2010@2|Bacteria,1MZSK@1224|Proteobacteria,2UC5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158351_k127_1931510_3	1906.SFRA_16320	8.412e-25	117.0	COG0745@1|root,COG0745@2|Bacteria,2GMVN@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1931510_4	47716.JOFH01000003_gene547	5.044e-09	61.0	COG0745@1|root,COG0745@2|Bacteria,2I1NS@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1931510_0	284031.JNXD01000002_gene6137	5.5e-79	285.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.25,6.2.1.50	ko:K00666,ko:K04110,ko:K12424	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422,R11608,R11872,R11873	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1931510_1	469383.Cwoe_5882	1.483e-52	212.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4CPIG@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158351_k127_1961504_3	1038859.AXAU01000001_gene3133	2.707e-80	291.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
SRR25158351_k127_1961504_0	331113.SNE_A06750	6.421e-145	477.0	COG0664@1|root,COG1252@1|root,COG0664@2|Bacteria,COG1252@2|Bacteria,2JFCT@204428|Chlamydiae	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885,ko:K10716	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Abhydrolase_6,CBS,Ion_trans,Pyr_redox_2,cNMP_binding
SRR25158351_k127_1961504_1	316274.Haur_1430	4.354e-112	399.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158351_k127_1961504_7	469371.Tbis_3100	1.176e-22	101.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4E6IW@85010|Pseudonocardiales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158351_k127_1961504_10	1121924.ATWH01000003_gene1666	2.681e-07	62.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria,4FQYF@85023|Microbacteriaceae	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158351_k127_1961504_9	73044.JNXP01000013_gene1350	6.841e-08	62.0	COG0662@1|root,COG0662@2|Bacteria,2HAW4@201174|Actinobacteria	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR25158351_k127_1961504_4	42256.RradSPS_2500	3.057e-72	265.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1611,DUF1611_N,Peptidase_S8
SRR25158351_k127_1961504_2	42256.RradSPS_2501	3.619e-98	338.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4CQUX@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_1961504_5	42256.RradSPS_2502	1.105e-51	190.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Putative_PNPOx
SRR25158351_k127_1961504_8	106370.Francci3_0166	6.389e-17	93.0	COG2755@1|root,COG2755@2|Bacteria,2GRDF@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158351_k127_197194_4	313612.L8106_30305	4.533e-08	55.0	COG1181@1|root,COG1181@2|Bacteria,1G1XR@1117|Cyanobacteria,1H855@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158351_k127_197194_3	696281.Desru_2822	1.14e-18	97.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,2593B@186801|Clostridia,2628M@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158351_k127_197194_2	211114.JOEF01000008_gene1356	1.667e-37	158.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DYBT@85010|Pseudonocardiales	201174|Actinobacteria	L	Tyrosine recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158351_k127_197194_1	1236902.ANAS01000008_gene2355	1.327e-46	179.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4EN22@85012|Streptosporangiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158351_k127_197194_0	1122939.ATUD01000013_gene869	5.086e-81	289.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158351_k127_197194_5	443143.GM18_1481	7.159e-07	52.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,43TEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_197426_3	1353529.M899_0925	1.571e-57	215.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,42UNJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158351_k127_197426_5	338969.Rfer_0415	2.479e-40	163.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,4AICZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158351_k127_197426_6	1026882.MAMP_02509	4.547e-38	156.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria,462R7@72273|Thiotrichales	72273|Thiotrichales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_197426_2	357808.RoseRS_1298	8.933e-70	239.0	COG2343@1|root,COG2343@2|Bacteria,2GARM@200795|Chloroflexi,3775Q@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_197426_1	1242864.D187_006689	1.919e-79	277.0	COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158351_k127_197426_4	272560.BPSL2175	4.353e-51	194.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2VR4K@28216|Betaproteobacteria,1K18T@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158351_k127_197426_0	316057.RPD_4216	5.611e-117	392.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,2TSHG@28211|Alphaproteobacteria,3K09N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158351_k127_197426_7	478741.JAFS01000002_gene530	9.533e-11	63.0	COG0450@1|root,COG0450@2|Bacteria,46TAE@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158351_k127_1978128_7	1274374.CBLK010000086_gene4576	1.967e-47	175.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,26TQV@186822|Paenibacillaceae	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158351_k127_1978128_1	479434.Sthe_1110	3.109e-153	499.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi,27XMG@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_1978128_11	28042.GU90_16765	1.258e-14	78.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4E6ZN@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR1	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158351_k127_1978128_0	1123320.KB889585_gene1820	0.0	1082.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158351_k127_1978128_3	292415.Tbd_0965	8.444e-105	357.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,1KRJ1@119069|Hydrogenophilales	119069|Hydrogenophilales	L	KaiC	-	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
SRR25158351_k127_1978128_5	469383.Cwoe_1687	1.827e-68	242.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CPVJ@84995|Rubrobacteria	84995|Rubrobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158351_k127_1978128_4	264732.Moth_2488	4.002e-71	255.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,42EMS@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Nucleotide binding protein, PINc	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
SRR25158351_k127_1978128_10	1267535.KB906767_gene3254	2.644e-34	143.0	COG1801@1|root,COG1801@2|Bacteria,3Y2F1@57723|Acidobacteria,2JHKY@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158351_k127_1978128_8	1122939.ATUD01000002_gene1190	1.318e-41	163.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CQE7@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158351_k127_1978128_6	867903.ThesuDRAFT_01993	4.288e-59	215.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR25158351_k127_1978128_9	1030157.AFMP01000011_gene3779	2.987e-40	155.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales	204457|Sphingomonadales	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158351_k127_1978128_2	1283299.AUKG01000001_gene3020	1.267e-114	383.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CP99@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158351_k127_198436_8	469383.Cwoe_0900	8.041e-24	102.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4CT93@84995|Rubrobacteria	84995|Rubrobacteria	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158351_k127_198436_0	469383.Cwoe_0899	1.278e-193	612.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CS9X@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158351_k127_198436_5	312284.A20C1_07031	2.981e-36	145.0	COG2207@1|root,COG2207@2|Bacteria,2GNU7@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158351_k127_198436_3	312284.A20C1_07036	5.538e-85	289.0	COG4922@1|root,COG4922@2|Bacteria,2IA0H@201174|Actinobacteria	201174|Actinobacteria	O	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158351_k127_198436_13	1122175.ATXU01000008_gene328	7.601e-10	66.0	28XY1@1|root,2ZJTZ@2|Bacteria,2GZGA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_198436_11	396014.BF93_09035	7.854e-20	102.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,4FDB5@85020|Dermabacteraceae	201174|Actinobacteria	CH	FAD binding domain	mhpA	-	1.14.13.127,1.14.13.219,1.14.13.220	ko:K05712,ko:K16022,ko:K20943,ko:K20944	ko00360,ko00362,ko01051,ko01052,ko01120,ko01220,map00360,map00362,map01051,map01052,map01120,map01220	M00545	R05249,R06786,R06787,R11347	RC00046,RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158351_k127_198436_6	390989.JOEG01000005_gene2081	4.183e-31	130.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria,4DGHF@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_198436_2	189753.AXAS01000021_gene1869	8.997e-91	312.0	COG0665@1|root,COG0665@2|Bacteria,1PEBQ@1224|Proteobacteria,2TRZ6@28211|Alphaproteobacteria,3JRIQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158351_k127_198436_12	1122609.AUGT01000009_gene3300	4.096e-17	96.0	COG2931@1|root,COG2931@2|Bacteria,2HRU5@201174|Actinobacteria,4DW0Z@85009|Propionibacteriales	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158351_k127_198436_10	926550.CLDAP_31700	1.233e-20	107.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.4	ko:K01312	ko04080,ko04972,ko04974,ko05164,map04080,map04972,map04974,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	DUF4384,PPC,Trypsin,VCBS
SRR25158351_k127_198436_14	1121033.AUCF01000006_gene4194	8.137e-10	69.0	COG2021@1|root,COG2021@2|Bacteria,1RDEH@1224|Proteobacteria,2U267@28211|Alphaproteobacteria,2JS8S@204441|Rhodospirillales	204441|Rhodospirillales	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_198436_1	446466.Cfla_2023	1.678e-150	488.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158351_k127_198436_7	469383.Cwoe_5525	3.841e-24	113.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4CTMT@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158351_k127_198436_4	58123.JOFJ01000033_gene59	1.911e-57	207.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4ER5R@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_198436_9	318996.AXAZ01000010_gene5554	1.507e-21	106.0	COG0346@1|root,COG0346@2|Bacteria,1RABQ@1224|Proteobacteria,2VGD1@28211|Alphaproteobacteria,3JYAI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_1989282_11	1380386.JIAW01000010_gene4169	2.079e-08	67.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria,23583@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
SRR25158351_k127_1989282_7	1121920.AUAU01000004_gene665	6.146e-63	234.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1989282_6	1306406.ASHX01000001_gene4081	9.176e-69	252.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1989282_0	42256.RradSPS_2071	9.29e-186	603.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158351_k127_1989282_3	365528.KB891103_gene4159	2.587e-83	286.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria,4EUEV@85013|Frankiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_1989282_8	469383.Cwoe_4227	2.264e-62	224.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CPYI@84995|Rubrobacteria	84995|Rubrobacteria	S	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158351_k127_1989282_2	42256.RradSPS_1158	1.964e-89	304.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158351_k127_1989282_9	298655.KI912266_gene1029	1.799e-48	183.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_1989282_4	1380356.JNIK01000019_gene208	7.26e-71	252.0	COG1162@1|root,COG1162@2|Bacteria,2GMDX@201174|Actinobacteria	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158351_k127_1989282_1	1179773.BN6_83040	1.247e-100	338.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4E0C3@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158351_k127_1989282_10	1446473.JHWH01000009_gene322	2.041e-10	73.0	COG0785@1|root,COG0785@2|Bacteria,1RBAA@1224|Proteobacteria,2U6KU@28211|Alphaproteobacteria,2PWJY@265|Paracoccus	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein	mauF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1989282_12	1121943.KB899991_gene2682	4.483e-07	61.0	COG1225@1|root,COG1225@2|Bacteria,1QV25@1224|Proteobacteria	1224|Proteobacteria	O	methylamine metabolic process	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158351_k127_1989282_5	1123070.KB899247_gene1438	3.051e-70	250.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,2ITUD@203494|Verrucomicrobiae	74201|Verrucomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158351_k127_2023001_5	469383.Cwoe_3181	6.234e-129	422.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CP8G@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158351_k127_2023001_12	356851.JOAN01000007_gene4102	1.437e-15	80.0	COG1862@1|root,COG1862@2|Bacteria,2IQSP@201174|Actinobacteria,4DF8H@85008|Micromonosporales	201174|Actinobacteria	U	Preprotein translocase	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158351_k127_2023001_1	469383.Cwoe_3183	3.208e-197	651.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158351_k127_2023001_16	760568.Desku_1494	8.343e-08	59.0	COG3937@1|root,COG3937@2|Bacteria,1VF6E@1239|Firmicutes,24QR5@186801|Clostridia,2635Z@186807|Peptococcaceae	186801|Clostridia	S	ATP synthase, subunit b	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR25158351_k127_2023001_7	555079.Toce_1529	3.079e-95	332.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia,42FDX@68295|Thermoanaerobacterales	186801|Clostridia	S	pfam abc1	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
SRR25158351_k127_2023001_6	1380390.JIAT01000010_gene4888	5.35e-115	402.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158351_k127_2023001_0	469383.Cwoe_3187	2.008e-294	920.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158351_k127_2023001_2	42256.RradSPS_2485	1.58e-184	595.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158351_k127_2023001_3	1283299.AUKG01000001_gene3172	6.115e-172	572.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158351_k127_2023001_4	469383.Cwoe_3191	8.398e-162	522.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4CPCC@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_2023001_11	471852.Tcur_0802	1.816e-23	107.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4EKIY@85012|Streptosporangiales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_2023001_15	1124780.ANNU01000035_gene286	1.684e-08	66.0	COG0451@1|root,COG0451@2|Bacteria,4NHCV@976|Bacteroidetes	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158351_k127_2023001_13	1123065.ATWL01000011_gene32	5.132e-15	82.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158351_k127_2023001_10	1172179.AUKV01000001_gene918	2.701e-26	118.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_2023001_17	1207076.ALAT01000215_gene4051	1.992e-05	49.0	COG0477@1|root,COG0477@2|Bacteria,1QTWJ@1224|Proteobacteria,1T1QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	mdtD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K18326	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.3.26	-	-	MFS_1,MFS_3,TRI12
SRR25158351_k127_2023001_14	1869.MB27_23065	1.415e-12	77.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,4DIEG@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_2023001_8	1133850.SHJG_2266	4.259e-81	277.0	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-phosphoglucomutase family hydrolase	-	GO:0003674,GO:0003824,GO:0008801,GO:0016853,GO:0016866,GO:0016868	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
SRR25158351_k127_2023001_9	1232410.KI421424_gene1796	6.453e-32	129.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.230,2.4.1.64	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158351_k127_205266_7	1442599.JAAN01000011_gene395	2.902e-18	96.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158351_k127_205266_4	478741.JAFS01000001_gene1160	8.971e-38	147.0	COG1528@1|root,COG1528@2|Bacteria,46WDU@74201|Verrucomicrobia,37GM9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Ferritin-like domain	ftn	-	1.16.3.1,1.16.3.2	ko:K02217,ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158351_k127_205266_5	1283299.AUKG01000002_gene4646	6.026e-32	131.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4CQE6@84995|Rubrobacteria	84995|Rubrobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158351_k127_205266_3	768710.DesyoDRAFT_0987	1.127e-57	209.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,261JB@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158351_k127_205266_6	1283299.AUKG01000002_gene4640	1.286e-30	134.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CPY7@84995|Rubrobacteria	84995|Rubrobacteria	K	Segregation and condensation complex subunit ScpB	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158351_k127_205266_9	931626.Awo_c09680	1.938e-12	79.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,25VKF@186806|Eubacteriaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158351_k127_205266_10	1461577.CCMH01000037_gene27	5.556e-05	55.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,1I1PX@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX protease	sagE	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158351_k127_205266_8	1382306.JNIM01000001_gene722	8.341e-13	78.0	COG0664@1|root,COG0664@2|Bacteria,2G6YS@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158351_k127_205266_2	1122609.AUGT01000022_gene731	6.814e-58	223.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DN8K@85009|Propionibacteriales	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158351_k127_205266_0	1440053.JOEI01000019_gene609	1.028e-94	320.0	COG0596@1|root,COG0596@2|Bacteria,2GJCT@201174|Actinobacteria	201174|Actinobacteria	F	Alpha beta hydrolase	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158351_k127_205266_1	35754.JNYJ01000001_gene7308	4.615e-74	259.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DA75@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_2054577_1	469383.Cwoe_1846	2.059e-115	377.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_2054577_3	469383.Cwoe_1850	1.149e-39	151.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4CQGR@84995|Rubrobacteria	84995|Rubrobacteria	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158351_k127_2054577_6	1449976.KALB_722	0.0007364	48.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DXHB@85010|Pseudonocardiales	201174|Actinobacteria	T	response regulator	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_2054577_2	671143.DAMO_2568	1.173e-61	235.0	COG1432@1|root,COG1432@2|Bacteria,2NQWI@2323|unclassified Bacteria	2|Bacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158351_k127_2054577_0	929712.KI912613_gene2190	1.087e-207	658.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158351_k127_2054577_4	1173024.KI912148_gene3341	6.424e-12	75.0	COG1846@1|root,COG1846@2|Bacteria,1G6CB@1117|Cyanobacteria,1JJHC@1189|Stigonemataceae	1117|Cyanobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158351_k127_2054577_5	1236902.ANAS01000007_gene3922	0.000695	46.0	28KEQ@1|root,2ZA0Y@2|Bacteria,2GJZM@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4429,SHOCT
SRR25158351_k127_2066116_0	211165.AJLN01000096_gene5033	4.34e-109	361.0	COG0364@1|root,COG0364@2|Bacteria,1GI0D@1117|Cyanobacteria,1JJHW@1189|Stigonemataceae	1117|Cyanobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	G6PD_C,G6PD_N
SRR25158351_k127_2066116_4	710696.Intca_0153	8.213e-06	55.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4FGWB@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_2066116_2	326424.FRAAL1397	9.016e-32	141.0	2CF7S@1|root,2ZB6P@2|Bacteria,2H77W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_2066116_3	195250.CM001776_gene2910	6.426e-12	76.0	COG0500@1|root,COG2226@2|Bacteria,1G55Q@1117|Cyanobacteria,1H0RB@1129|Synechococcus	1117|Cyanobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_2066116_1	1382306.JNIM01000001_gene549	1.886e-57	202.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi	200795|Chloroflexi	G	TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating)	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158351_k127_209513_2	66269.NL54_11770	4.727e-48	176.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RQE4@1236|Gammaproteobacteria,3W257@53335|Pantoea	1236|Gammaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158351_k127_209513_6	1123023.JIAI01000008_gene1510	1.743e-15	79.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4E0UH@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_209513_8	443218.AS9A_2522	8.745e-09	57.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,2334N@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_209513_1	1172179.AUKV01000003_gene7383	4.522e-51	188.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_209513_7	1054860.KB913030_gene340	1.571e-14	80.0	COG4941@1|root,COG4974@1|root,COG4941@2|Bacteria,COG4974@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_209513_4	861299.J421_2147	4.762e-25	112.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158351_k127_209513_3	1122939.ATUD01000006_gene1646	5.109e-28	121.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_209513_5	749414.SBI_09171	2.836e-24	111.0	COG3619@1|root,COG3619@2|Bacteria,2GKDV@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
SRR25158351_k127_209513_0	1463845.JOIG01000001_gene1740	1.691e-112	377.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158351_k127_217729_20	1380390.JIAT01000017_gene5301	2.811e-43	167.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CQ8W@84995|Rubrobacteria	84995|Rubrobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158351_k127_217729_23	1122138.AQUZ01000054_gene5902	1.303e-25	119.0	COG0819@1|root,COG0819@2|Bacteria,2IGXQ@201174|Actinobacteria	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)	-	-	-	ko:K20896	ko00730,ko01100,map00730,map01100	-	R09993,R11313	RC00197,RC02832	ko00000,ko00001,ko01000	-	-	-	TENA_THI-4
SRR25158351_k127_217729_32	446466.Cfla_1600	9.872e-09	66.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4F2IT@85016|Cellulomonadaceae	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158351_k127_217729_8	1128421.JAGA01000002_gene1530	4.196e-81	283.0	COG0009@1|root,COG0009@2|Bacteria,2NPMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the SUA5 family	sua5	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158351_k127_217729_6	561175.KB894096_gene539	2.622e-95	324.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4EFX2@85012|Streptosporangiales	201174|Actinobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_217729_31	420324.KI911947_gene5609	1.562e-13	77.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,1JURB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158351_k127_217729_0	469383.Cwoe_5273	2.364e-291	920.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPC3@84995|Rubrobacteria	84995|Rubrobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158351_k127_217729_11	1150864.MILUP08_45428	1.789e-76	271.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158351_k127_217729_29	1089550.ATTH01000001_gene2568	7.295e-17	87.0	2AB5V@1|root,310K1@2|Bacteria,4PF5E@976|Bacteroidetes,1FK69@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_217729_10	543632.JOJL01000035_gene5070	1.108e-76	270.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158351_k127_217729_27	929712.KI912613_gene4702	2.769e-19	93.0	2B6US@1|root,31ZU9@2|Bacteria,2HRE3@201174|Actinobacteria,4CTC7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_217729_2	1123242.JH636434_gene5621	4.714e-177	569.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158351_k127_217729_28	1123251.ATWM01000002_gene80	2.002e-18	89.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4FFKQ@85021|Intrasporangiaceae	201174|Actinobacteria	P	Potassium transporter CPA	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
SRR25158351_k127_217729_15	1380390.JIAT01000010_gene3523	7.108e-61	220.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4CRMU@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
SRR25158351_k127_217729_21	1121438.JNJA01000012_gene1560	4.396e-35	140.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2WPJY@28221|Deltaproteobacteria,2MBJ3@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
SRR25158351_k127_217729_30	1283299.AUKG01000004_gene948	5.288e-15	83.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4CQAS@84995|Rubrobacteria	84995|Rubrobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158351_k127_217729_14	639283.Snov_1164	9.285e-67	234.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,3EZ9U@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158351_k127_217729_35	1463926.JOCA01000004_gene4990	1.781e-05	51.0	28VA1@1|root,2ZHCY@2|Bacteria,2INFH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158351_k127_217729_34	1380347.JNII01000008_gene4035	5.984e-06	53.0	2BYGI@1|root,333FU@2|Bacteria,2GRMH@201174|Actinobacteria	201174|Actinobacteria	S	Subtilisin inhibitor-like	-	-	-	-	-	-	-	-	-	-	-	-	SSI
SRR25158351_k127_217729_22	246196.MSMEI_2086	5.049e-27	115.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,2396M@1762|Mycobacteriaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158351_k127_217729_25	1298860.AUEM01000006_gene2609	1.09e-21	104.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158351_k127_217729_4	469383.Cwoe_3057	1.81e-133	439.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CPJG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158351_k127_217729_24	246200.SPO1634	1.432e-25	114.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,4NAT3@97050|Ruegeria	28211|Alphaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158351_k127_217729_13	555088.DealDRAFT_1397	2.446e-70	256.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,42JQW@68298|Syntrophomonadaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158351_k127_217729_19	469383.Cwoe_3059	5.358e-46	170.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158351_k127_217729_9	469383.Cwoe_3060	4.285e-80	287.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CPI6@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158351_k127_217729_17	591158.SSMG_02243	1.232e-56	205.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158351_k127_217729_16	429009.Adeg_1284	1.207e-58	227.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,42EY5@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Conserved carboxylase region	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158351_k127_217729_3	1128421.JAGA01000002_gene1735	9.839e-149	491.0	COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria	2|Bacteria	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158351_k127_217729_26	469383.Cwoe_3073	3.905e-20	95.0	COG0781@1|root,COG0781@2|Bacteria,2HP01@201174|Actinobacteria,4CQ9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158351_k127_217729_1	469383.Cwoe_3076	5.047e-221	706.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CPJ0@84995|Rubrobacteria	84995|Rubrobacteria	HI	1-deoxy-D-xylulose-5-phosphate synthase	-	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158351_k127_217729_12	1380390.JIAT01000003_gene5441	1.38e-73	260.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CQ7R@84995|Rubrobacteria	84995|Rubrobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158351_k127_217729_18	469383.Cwoe_3081	8.388e-49	190.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158351_k127_217729_7	1122939.ATUD01000005_gene2648	1.068e-88	314.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CPSV@84995|Rubrobacteria	84995|Rubrobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158351_k127_217729_5	525904.Tter_2834	1.497e-98	331.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	ytcB	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158351_k127_217729_33	519989.ECTPHS_12363	7.159e-07	52.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158351_k127_233351_0	1313172.YM304_41740	7.669e-145	480.0	COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_233351_2	1313172.YM304_41730	4.784e-42	165.0	2DQVM@1|root,338Y0@2|Bacteria	2|Bacteria	S	lipid binding	lprG	GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561	-	ko:K14954,ko:K14955	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
SRR25158351_k127_233351_3	2002.JOEQ01000020_gene7083	8.35e-08	63.0	COG3266@1|root,COG3266@2|Bacteria,2GQ3D@201174|Actinobacteria,4EK9A@85012|Streptosporangiales	201174|Actinobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158351_k127_233351_4	1278073.MYSTI_07865	4.364e-07	58.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158351_k127_233351_5	1453505.JASY01000015_gene4427	6.337e-06	59.0	2DC24@1|root,2ZCJC@2|Bacteria,4P4T2@976|Bacteroidetes	976|Bacteroidetes	S	Beta-1,3-glucanase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_64
SRR25158351_k127_233351_1	1348338.ADILRU_2126	3.515e-72	266.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4FN0I@85023|Microbacteriaceae	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_233351_6	419947.MRA_2459	1.281e-05	53.0	COG0500@1|root,COG2226@2|Bacteria,2GZ6C@201174|Actinobacteria,23EK2@1762|Mycobacteriaceae	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_240030_1	471853.Bcav_1854	1.587e-24	121.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158351_k127_240030_0	926560.KE387027_gene1038	1.737e-87	304.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158351_k127_241756_6	67356.KL575668_gene7269	1.7e-11	75.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158351_k127_241756_1	1207058.L53_09380	7.65e-90	304.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2TRC6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_241756_0	35754.JNYJ01000053_gene6711	1.673e-100	357.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DI8A@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_241756_3	592015.HMPREF1705_00887	1.347e-21	109.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_241756_2	395961.Cyan7425_1861	1.54e-88	304.0	COG0604@1|root,COG0604@2|Bacteria,1GQ2K@1117|Cyanobacteria	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_241756_5	1288494.EBAPG3_17690	6.551e-20	97.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,3736N@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_241756_4	930171.Asphe3_23910	2.407e-21	104.0	COG3832@1|root,COG3832@2|Bacteria,2HK0N@201174|Actinobacteria,1WC5C@1268|Micrococcaceae	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_260956_1	880073.Calab_0387	9.801e-18	91.0	28TMI@1|root,2ZFV4@2|Bacteria	2|Bacteria	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
SRR25158351_k127_260956_3	242159.ABP00758	0.0006076	53.0	COG2940@1|root,KOG2084@2759|Eukaryota,37IMX@33090|Viridiplantae,34HPP@3041|Chlorophyta	3041|Chlorophyta	B	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_260956_2	882082.SaccyDRAFT_4569	6.431e-06	57.0	2E39G@1|root,32Y91@2|Bacteria,2GQNT@201174|Actinobacteria,4E705@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_260956_0	1382356.JQMP01000004_gene486	0.0	1077.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158351_k127_264406_3	5786.XP_003288076.1	0.0006232	49.0	COG3664@1|root,2SV6Z@2759|Eukaryota,3XAF9@554915|Amoebozoa	554915|Amoebozoa	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_264406_0	1380390.JIAT01000011_gene2878	3.926e-61	230.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CRCH@84995|Rubrobacteria	201174|Actinobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158351_k127_264406_2	290399.Arth_2885	2.827e-07	57.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158351_k127_264406_1	1122165.AUHS01000003_gene1982	1.626e-07	53.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1JEBZ@118969|Legionellales	118969|Legionellales	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158351_k127_276561_5	1267533.KB906739_gene2521	1.345e-54	204.0	COG1562@1|root,COG1562@2|Bacteria,3Y3YX@57723|Acidobacteria,2JIHF@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158351_k127_276561_2	1146883.BLASA_0213	2.671e-89	314.0	COG1232@1|root,COG1232@2|Bacteria,2I2Z5@201174|Actinobacteria,4ERME@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	hopC	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_276561_0	298654.FraEuI1c_2169	6.16e-179	584.0	COG2409@1|root,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria,4EURS@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_276561_9	1206101.AZXC01000013_gene928	8.328e-28	123.0	COG2343@1|root,COG2343@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_276561_15	2074.JNYD01000013_gene6806	4.766e-07	61.0	COG0697@1|root,COG0697@2|Bacteria,2GRQC@201174|Actinobacteria,4E6PE@85010|Pseudonocardiales	201174|Actinobacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_276561_11	1122939.ATUD01000001_gene439	6.215e-24	115.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4CRYZ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158351_k127_276561_3	1380390.JIAT01000016_gene5653	7.624e-84	289.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CRC4@84995|Rubrobacteria	84995|Rubrobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158351_k127_276561_17	1123368.AUIS01000019_gene1200	0.0001358	49.0	2EFT9@1|root,339JC@2|Bacteria,1PU20@1224|Proteobacteria,1T8MH@1236|Gammaproteobacteria,2ND43@225057|Acidithiobacillales	225057|Acidithiobacillales	S	MerR HTH family regulatory protein	-	-	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
SRR25158351_k127_276561_4	1163409.UUA_01764	5.773e-65	229.0	COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,1T4W8@1236|Gammaproteobacteria,1XDGU@135614|Xanthomonadales	135614|Xanthomonadales	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158351_k127_276561_18	290402.Cbei_2306	0.0004705	50.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36F0S@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158351_k127_276561_16	326424.FRAAL1760	6.285e-05	51.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4ESUR@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_276561_10	795797.C497_05867	3.674e-26	113.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,23WU7@183963|Halobacteria	183963|Halobacteria	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158351_k127_276561_6	469383.Cwoe_5209	3.358e-52	197.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CPJE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158351_k127_276561_14	1282876.BAOK01000001_gene2277	3.417e-09	68.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_276561_7	469383.Cwoe_4669	5.256e-46	179.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4CPXW@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158351_k127_276561_1	1283299.AUKG01000002_gene3802	2.892e-90	318.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4CPUJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158351_k127_276561_13	1463936.JOJI01000029_gene3263	3.906e-13	81.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_276561_8	469383.Cwoe_4680	6.339e-36	142.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4CQEM@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158351_k127_276561_12	469383.Cwoe_4683	7.715e-23	102.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_286975_0	1121430.JMLG01000001_gene2387	1.044e-149	490.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24BRX@186801|Clostridia,260H8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158351_k127_286975_1	469383.Cwoe_0941	2.279e-98	330.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4CTIQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.12	-	-	MIP
SRR25158351_k127_286975_4	948565.AFFP02000028_gene28	1.225e-05	51.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_286975_5	1907.SGLAU_10055	1.68e-05	47.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158351_k127_286975_3	318424.EU78_13220	2.72e-08	63.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,2360Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158351_k127_286975_2	1121468.AUBR01000033_gene1207	9.656e-50	184.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,42G27@68295|Thermoanaerobacterales	186801|Clostridia	K	response regulator	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_287846_9	700508.D174_18655	5.847e-08	65.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,23321@1762|Mycobacteriaceae	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158351_k127_287846_3	429009.Adeg_0876	1.557e-42	172.0	COG3598@1|root,COG3598@2|Bacteria,1UKDF@1239|Firmicutes,25FUJ@186801|Clostridia,42GPU@68295|Thermoanaerobacterales	2|Bacteria	L	PFAM Bifunctional DNA primase polymerase	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	AAA_25,PriCT_1,Prim-Pol
SRR25158351_k127_287846_7	1502851.FG93_00015	9.702e-12	70.0	COG0662@1|root,COG0662@2|Bacteria,1QY4P@1224|Proteobacteria,2TZWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_287846_4	469383.Cwoe_3950	4.443e-34	136.0	2A4HN@1|root,30T46@2|Bacteria,2HRPH@201174|Actinobacteria,4CTRU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_287846_5	1043493.BBLU01000006_gene2226	1.515e-25	113.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	ycnJ	-	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD
SRR25158351_k127_287846_8	644283.Micau_3972	4.271e-08	64.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	ycnJ	-	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD
SRR25158351_k127_287846_0	1380386.JIAW01000027_gene7127	7.842e-126	428.0	2B6T0@1|root,31ZS8@2|Bacteria,2H2K7@201174|Actinobacteria,23CW4@1762|Mycobacteriaceae	201174|Actinobacteria	S	SAM dependent carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_7
SRR25158351_k127_287846_6	1120949.KB903294_gene3790	5.523e-24	117.0	COG0584@1|root,COG0584@2|Bacteria,2GVYH@201174|Actinobacteria,4DIUF@85008|Micromonosporales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_287846_1	1048339.KB913029_gene4254	7.081e-55	202.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158351_k127_30091_4	42256.RradSPS_0178	0.0002803	51.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158351_k127_30091_1	298654.FraEuI1c_2450	3.801e-19	100.0	2DF97@1|root,2ZQZA@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158351_k127_30091_0	656024.FsymDg_2923	1.889e-23	115.0	2DF97@1|root,2ZQZA@2|Bacteria	2|Bacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158351_k127_30091_3	110319.CF8_2730	2.396e-05	53.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158351_k127_30091_5	1408423.JHYA01000004_gene2259	0.000653	53.0	COG4655@1|root,COG4655@2|Bacteria,1U4UD@1239|Firmicutes,4H68M@909932|Negativicutes	909932|Negativicutes	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158351_k127_308066_0	264732.Moth_0568	4.803e-287	906.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158351_k127_308066_1	345341.KUTG_07923	1.189e-17	91.0	COG0454@1|root,COG0456@2|Bacteria,2IR11@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158351_k127_308066_2	1229780.BN381_30044	1.452e-08	64.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,3UWW3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158351_k127_312379_6	861299.J421_4371	1.364e-49	192.0	COG1215@1|root,COG1215@2|Bacteria,1ZU0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158351_k127_312379_5	42256.RradSPS_0138	2.866e-62	224.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4CQ34@84995|Rubrobacteria	84995|Rubrobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158351_k127_312379_1	1229780.BN381_430003	2.117e-143	482.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_312379_0	1382356.JQMP01000001_gene1155	2.086e-199	630.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi,27XSD@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_312379_8	1352941.M877_01565	5.498e-34	149.0	COG4129@1|root,COG4129@2|Bacteria,2I3V3@201174|Actinobacteria	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158351_k127_312379_10	222534.KB893714_gene1603	9.593e-10	66.0	COG1289@1|root,COG1289@2|Bacteria,2GN9U@201174|Actinobacteria	201174|Actinobacteria	S	Fusaric acid resistance protein-like	yccS_1	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158351_k127_312379_9	426716.JOAJ01000008_gene4763	2.389e-12	78.0	2B2T9@1|root,31VDM@2|Bacteria,2HWS3@201174|Actinobacteria,4FZIF@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_312379_4	439235.Dalk_0528	2.047e-63	228.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2MNNY@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_312379_2	35754.JNYJ01000003_gene6596	2.908e-95	323.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DBXY@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_312379_11	926560.KE387027_gene633	5.681e-07	59.0	COG1917@1|root,COG3832@1|root,COG1917@2|Bacteria,COG3832@2|Bacteria,1WN52@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_312379_3	255470.cbdbA734	1.696e-72	255.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi,34CXZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_313092_10	760568.Desku_1552	5.871e-91	306.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158351_k127_313092_31	1283299.AUKG01000001_gene1793	3.198e-07	59.0	2AWJ7@1|root,31NFU@2|Bacteria,2HR1C@201174|Actinobacteria,4CSVI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_313092_4	1382356.JQMP01000001_gene827	5.162e-140	464.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_313092_6	1123252.ATZF01000009_gene661	7.831e-108	370.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,4HAAQ@91061|Bacilli,27CKF@186824|Thermoactinomycetaceae	91061|Bacilli	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
SRR25158351_k127_313092_24	1380390.JIAT01000014_gene6193	2.788e-41	161.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158351_k127_313092_22	1089551.KE386572_gene2405	2.069e-46	177.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,4BQ87@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158351_k127_313092_11	469383.Cwoe_4639	5.316e-78	280.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CPAU@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158351_k127_313092_17	1380390.JIAT01000009_gene376	6.532e-62	222.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CPQ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158351_k127_313092_21	1380390.JIAT01000009_gene1813	1.457e-50	197.0	COG1668@1|root,COG1668@2|Bacteria,2HNDN@201174|Actinobacteria,4CP6Y@84995|Rubrobacteria	84995|Rubrobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158351_k127_313092_23	1283299.AUKG01000001_gene1784	5.636e-45	173.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4CRAH@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158351_k127_313092_14	469383.Cwoe_5935	2.951e-68	243.0	COG1692@1|root,COG1692@2|Bacteria,2IG59@201174|Actinobacteria,4CQ4Z@84995|Rubrobacteria	84995|Rubrobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158351_k127_313092_30	335543.Sfum_2785	2.945e-12	77.0	COG1388@1|root,COG3770@1|root,COG1388@2|Bacteria,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,42VK7@68525|delta/epsilon subdivisions,2WS1M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	LysM domain protein	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M74
SRR25158351_k127_313092_27	266117.Rxyl_1043	3.861e-25	119.0	COG5650@1|root,COG5650@2|Bacteria,2HYCN@201174|Actinobacteria,4CQKH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158351_k127_313092_9	469383.Cwoe_5936	2.912e-99	348.0	2AU3I@1|root,31JPZ@2|Bacteria,2H277@201174|Actinobacteria,4CQ2S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_313092_28	1122939.ATUD01000013_gene903	7.206e-18	93.0	COG2246@1|root,COG2246@2|Bacteria,2HR1U@201174|Actinobacteria,4CSWB@84995|Rubrobacteria	84995|Rubrobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158351_k127_313092_3	469383.Cwoe_5940	3.122e-152	496.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPBA@84995|Rubrobacteria	84995|Rubrobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158351_k127_313092_8	1380390.JIAT01000009_gene1803	9.149e-100	335.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4CPJD@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158351_k127_313092_33	1197906.CAJQ02000023_gene2217	0.0006584	46.0	2EIP1@1|root,33CEE@2|Bacteria,1NE7R@1224|Proteobacteria,2UG1R@28211|Alphaproteobacteria,3K11G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR25158351_k127_313092_26	469383.Cwoe_1575	3.474e-35	145.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4CPUH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158351_k127_313092_2	1219049.SP5_001_00630	5.71e-191	619.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2JZZG@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158351_k127_313092_0	187272.Mlg_2132	0.0	1518.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1WW84@135613|Chromatiales	135613|Chromatiales	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158351_k127_313092_7	1121422.AUMW01000002_gene2193	7.473e-101	347.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_313092_5	429009.Adeg_0960	1.658e-119	397.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_313092_19	479434.Sthe_0375	3.378e-58	213.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,27XUY@189775|Thermomicrobia	189775|Thermomicrobia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_313092_13	926561.KB900622_gene598	5.057e-69	248.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WAGY@53433|Halanaerobiales	186801|Clostridia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158351_k127_313092_32	246194.CHY_2568	0.0006268	50.0	2DQT5@1|root,338GV@2|Bacteria,1VEES@1239|Firmicutes,24S7P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_313092_12	365528.KB891234_gene114	3.363e-69	242.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4ETZ6@85013|Frankiales	201174|Actinobacteria	K	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_313092_20	1394178.AWOO02000067_gene218	1.554e-55	215.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_313092_25	479432.Sros_8570	3.515e-41	156.0	COG5015@1|root,COG5015@2|Bacteria,2I3I5@201174|Actinobacteria,4EJIN@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_313092_15	1283299.AUKG01000001_gene2315	7.632e-66	247.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRQE@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158351_k127_313092_1	246196.MSMEI_5371	4.739e-192	617.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,232D7@1762|Mycobacteriaceae	201174|Actinobacteria	E	peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158351_k127_313092_16	471852.Tcur_1914	1.367e-64	236.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4EG3S@85012|Streptosporangiales	201174|Actinobacteria	L	Calcineurin-like phosphoesterase superfamily domain	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
SRR25158351_k127_313092_18	1540221.JQNI01000002_gene719	2.878e-58	231.0	COG0419@1|root,COG0419@2|Bacteria,1WJ38@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
SRR25158351_k127_317550_14	1123023.JIAI01000005_gene897	1.55e-18	92.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4E6IW@85010|Pseudonocardiales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158351_k127_317550_8	66429.JOFL01000010_gene1162	3.773e-41	167.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4,Peptidase_S9
SRR25158351_k127_317550_6	266117.Rxyl_2372	3.76e-63	222.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4CQ9H@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158351_k127_317550_3	710685.MycrhN_2907	2.896e-89	313.0	COG0165@1|root,COG0165@2|Bacteria,2I9W9@201174|Actinobacteria,23CB7@1762|Mycobacteriaceae	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158351_k127_317550_16	264732.Moth_1498	2.956e-08	61.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,42H30@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
SRR25158351_k127_317550_1	710111.FraQA3DRAFT_0636	3.517e-160	533.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158351_k127_317550_17	1194972.MVAC_06782	3.034e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,232P1@1762|Mycobacteriaceae	201174|Actinobacteria	M	PFAM glycosyl transferase, family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158351_k127_317550_15	1382306.JNIM01000001_gene233	2.058e-13	83.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT_2
SRR25158351_k127_317550_18	1047013.AQSP01000144_gene846	6.543e-05	56.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158351_k127_317550_12	1380394.JADL01000001_gene3056	1.139e-19	100.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2TTR9@28211|Alphaproteobacteria,2JQI8@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158351_k127_317550_13	203119.Cthe_2580	4.091e-19	96.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,257YU@186801|Clostridia,3WKCA@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158351_k127_317550_0	1382306.JNIM01000001_gene3339	8.807e-229	722.0	COG0129@1|root,COG0129@2|Bacteria,2G67Z@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158351_k127_317550_2	690850.Desaf_0633	8.542e-131	447.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,1MUB7@1224|Proteobacteria,42N14@68525|delta/epsilon subdivisions,2WIKT@28221|Deltaproteobacteria,2M8E0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_317550_9	1123258.AQXZ01000009_gene1445	4.836e-34	146.0	COG0438@1|root,COG0438@2|Bacteria,2GNYW@201174|Actinobacteria,4FVS4@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	pimC	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K14335	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_317550_7	58344.JOEL01000029_gene2933	4.494e-51	194.0	COG5002@1|root,COG5002@2|Bacteria,2GP6S@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158351_k127_317550_4	1463879.JOHP01000015_gene4530	2.273e-78	267.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_317550_10	880073.Calab_0387	4.983e-25	113.0	28TMI@1|root,2ZFV4@2|Bacteria	2|Bacteria	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
SRR25158351_k127_317550_11	351607.Acel_1595	1.696e-23	104.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4ERZW@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, winged helix family	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_317550_5	1449353.JQMQ01000005_gene1297	1.515e-69	242.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,2NM2E@228398|Streptacidiphilus	201174|Actinobacteria	M	Prolipoprotein diacylglyceryl transferase	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158351_k127_320052_5	63737.Npun_R3354	1.297e-07	59.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1HKGE@1161|Nostocales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind
SRR25158351_k127_320052_0	1229780.BN381_10285	2.535e-258	809.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,3UWDE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_320052_1	935866.JAER01000002_gene1939	1.024e-83	284.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DPH5@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_320052_2	2045.KR76_14325	7.018e-78	282.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4DPU1@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_320052_3	471853.Bcav_1854	2.246e-35	149.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158351_k127_320052_4	469383.Cwoe_5288	4.359e-35	141.0	COG4464@1|root,COG4464@2|Bacteria,2H0WF@201174|Actinobacteria,4CSZY@84995|Rubrobacteria	84995|Rubrobacteria	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158351_k127_330216_14	929712.KI912613_gene946	1.519e-27	121.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_330216_6	469383.Cwoe_1920	8.996e-77	272.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158351_k127_330216_0	1150469.RSPPHO_02004	2.702e-216	684.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2TU37@28211|Alphaproteobacteria,2JR71@204441|Rhodospirillales	204441|Rhodospirillales	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
SRR25158351_k127_330216_5	266117.Rxyl_1152	4.061e-84	296.0	COG0123@1|root,COG0123@2|Bacteria,2IDFT@201174|Actinobacteria,4CSQY@84995|Rubrobacteria	84995|Rubrobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158351_k127_330216_9	743836.AYNA01000038_gene824	9.322e-52	197.0	COG1028@1|root,COG1028@2|Bacteria,1Q7EW@1224|Proteobacteria,2TSMG@28211|Alphaproteobacteria,370CA@31993|Methylocystaceae	28211|Alphaproteobacteria	IQ	KR domain	gdh	-	1.1.1.100,1.1.1.47	ko:K00034,ko:K00059	ko00030,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00572	R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_330216_3	469383.Cwoe_5824	1.124e-153	523.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158351_k127_330216_7	469383.Cwoe_5827	5.349e-75	262.0	COG3481@1|root,COG3481@2|Bacteria,2HPRJ@201174|Actinobacteria,4CR4T@84995|Rubrobacteria	84995|Rubrobacteria	S	OB-fold nucleic acid binding domain	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
SRR25158351_k127_330216_12	469383.Cwoe_0188	3.959e-33	138.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_330216_11	1121385.AQXW01000004_gene3283	5.435e-34	137.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,1ZWBP@145357|Dermacoccaceae	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_330216_1	404589.Anae109_1606	4.976e-187	598.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,437ZU@68525|delta/epsilon subdivisions,2X39R@28221|Deltaproteobacteria,2YV0T@29|Myxococcales	28221|Deltaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158351_k127_330216_8	469383.Cwoe_2243	4.748e-69	245.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	yddR	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR25158351_k127_330216_16	1172188.KB911827_gene4233	5.395e-13	81.0	COG0726@1|root,COG0726@2|Bacteria,2GNFA@201174|Actinobacteria,4FHJB@85021|Intrasporangiaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158351_k127_330216_18	96561.Dole_0158	2.317e-06	55.0	COG3832@1|root,COG3832@2|Bacteria,1P4WC@1224|Proteobacteria,433A3@68525|delta/epsilon subdivisions,2WY95@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_330216_4	1120971.AUCA01000026_gene630	4.323e-86	297.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,277Y5@186823|Alicyclobacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158351_k127_330216_13	926560.KE387023_gene3017	1.939e-31	131.0	COG0346@1|root,COG0346@2|Bacteria,1WJZW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158351_k127_330216_2	469383.Cwoe_5866	3.961e-163	520.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR25158351_k127_330216_15	479434.Sthe_3291	6.71e-21	101.0	COG4549@1|root,COG4549@2|Bacteria	2|Bacteria	S	Domain of unkown function (DUF1775)	ycnI	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF1775
SRR25158351_k127_330216_10	1380390.JIAT01000009_gene1918	4.822e-51	191.0	COG3872@1|root,COG3872@2|Bacteria,2HQG9@201174|Actinobacteria,4CS1C@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158351_k127_330216_17	926554.KI912644_gene1540	4.42e-09	66.0	2EH1A@1|root,33ATA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_334704_1	1283299.AUKG01000002_gene3860	5.415e-36	151.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158351_k127_334704_8	1108045.GORHZ_125_00530	1.155e-06	57.0	COG3871@1|root,COG3871@2|Bacteria,2IQDD@201174|Actinobacteria,4GEM7@85026|Gordoniaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158351_k127_334704_7	1380358.JADJ01000012_gene616	1.212e-13	81.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1XJ9G@135619|Oceanospirillales	135619|Oceanospirillales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_334704_4	67356.KL575591_gene1467	2.12e-25	113.0	COG0599@1|root,COG0599@2|Bacteria,2IM93@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_334704_5	1283283.ATXA01000005_gene2097	1.222e-22	109.0	2DFS9@1|root,2ZSWU@2|Bacteria,2I7G3@201174|Actinobacteria	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR25158351_k127_334704_0	479433.Caci_3167	1.685e-96	329.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158351_k127_334704_6	479433.Caci_1074	2.639e-20	99.0	2DUW4@1|root,32UXY@2|Bacteria,2IJWI@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158351_k127_334704_2	502025.Hoch_0178	5.031e-34	150.0	COG3391@1|root,COG3391@2|Bacteria,1Q6NR@1224|Proteobacteria,433G0@68525|delta/epsilon subdivisions,2WXM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_334704_3	1123405.AUMM01000027_gene2125	7.331e-27	117.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,26Q0F@186821|Sporolactobacillaceae	91061|Bacilli	O	Disulfide bond formation protein DsbB	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158351_k127_336526_8	1157632.AQWQ01000007_gene3762	2.76e-79	270.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_336526_10	358823.DF19_01840	2.361e-67	243.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158351_k127_336526_1	469383.Cwoe_3715	1.793e-159	533.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_336526_3	1380393.JHVP01000004_gene617	1.314e-100	337.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4ES91@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_336526_5	1223542.GM1_021_00070	2.25e-98	335.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4GCPX@85026|Gordoniaceae	201174|Actinobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_336526_15	1123023.JIAI01000001_gene7344	4.334e-48	186.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4E0U1@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
SRR25158351_k127_336526_6	306281.AJLK01000010_gene5802	2.092e-89	303.0	COG0548@1|root,COG0548@2|Bacteria,1G0R4@1117|Cyanobacteria,1JH7U@1189|Stigonemataceae	1117|Cyanobacteria	E	Amino acid kinase family	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.argB	AA_kinase
SRR25158351_k127_336526_21	1122929.KB908234_gene4088	2.893e-10	66.0	2BPIW@1|root,32IBM@2|Bacteria,1Q8IH@1224|Proteobacteria,2UWE0@28211|Alphaproteobacteria	1122929.KB908234_gene4088|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_336526_7	309801.trd_0307	8.517e-88	308.0	COG0346@1|root,COG0346@2|Bacteria,2G5Y9@200795|Chloroflexi,27XVR@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158351_k127_336526_13	797209.ZOD2009_18025	1.835e-53	195.0	arCOG06256@1|root,arCOG06256@2157|Archaea,2XUA8@28890|Euryarchaeota,23TAD@183963|Halobacteria	183963|Halobacteria	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158351_k127_336526_2	485913.Krac_4927	1.691e-103	357.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158351_k127_336526_14	36809.MAB_2976	1.163e-51	196.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,233W3@1762|Mycobacteriaceae	201174|Actinobacteria	H	Riboflavin biosynthesis	ribD	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158351_k127_336526_11	1125863.JAFN01000001_gene2269	2.339e-64	236.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158351_k127_336526_9	469383.Cwoe_3615	3.08e-79	276.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CPXE@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158351_k127_336526_0	469383.Cwoe_3616	3.574e-197	642.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CP7V@84995|Rubrobacteria	84995|Rubrobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158351_k127_336526_4	1284352.AOIG01000003_gene1067	9.83e-100	336.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,26RWY@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158351_k127_336526_18	62928.azo1893	1.143e-27	123.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,2WGF7@28216|Betaproteobacteria,2KZVT@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158351_k127_336526_16	429009.Adeg_0536	3.341e-35	140.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,42GJ4@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158351_k127_336526_24	1134510.O9A_00371	0.0004295	47.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,48UAP@772|Bartonellaceae	28211|Alphaproteobacteria	J	structural constituent of ribosome	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158351_k127_336526_12	1137271.AZUM01000013_gene4338	2.76e-60	214.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DYUF@85010|Pseudonocardiales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158351_k127_336526_20	580340.Tlie_1670	2.548e-17	91.0	COG0776@1|root,COG0776@2|Bacteria,3TBC1@508458|Synergistetes	508458|Synergistetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158351_k127_336526_19	864069.MicloDRAFT_00056750	1.577e-25	121.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,1JRP9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158351_k127_336526_17	369723.Strop_0728	4.614e-28	130.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4DDT1@85008|Micromonosporales	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158351_k127_336526_23	1122182.KB903825_gene896	0.0001173	54.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4DCZ3@85008|Micromonosporales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158351_k127_336526_22	324602.Caur_3823	7.353e-08	62.0	COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158351_k127_368790_14	1211814.CAPG01000027_gene1356	3.237e-34	138.0	COG0490@1|root,COG0490@2|Bacteria,1V4YV@1239|Firmicutes,4IRH1@91061|Bacilli,1ZRUD@1386|Bacillus	91061|Bacilli	P	TrkA-C domain	khtT	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158351_k127_368790_17	710696.Intca_0760	2.563e-29	134.0	COG2172@1|root,COG2208@1|root,COG3447@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3447@2|Bacteria,2GJB0@201174|Actinobacteria,4FG40@85021|Intrasporangiaceae	201174|Actinobacteria	KT	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MASE1,SpoIIE
SRR25158351_k127_368790_3	512565.AMIS_48660	5.765e-128	417.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DCA3@85008|Micromonosporales	201174|Actinobacteria	P	membrane protein terC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158351_k127_368790_6	404589.Anae109_2517	2.204e-71	254.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
SRR25158351_k127_368790_16	296587.XP_002505010.1	1.619e-29	128.0	COG0278@1|root,KOG0911@2759|Eukaryota,37TQ7@33090|Viridiplantae,34IBA@3041|Chlorophyta	3041|Chlorophyta	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRR25158351_k127_368790_23	41431.PCC8801_3378	1.561e-14	82.0	COG0271@1|root,COG0271@2|Bacteria,1G7V3@1117|Cyanobacteria,3KIJY@43988|Cyanothece	1117|Cyanobacteria	T	Belongs to the BolA IbaG family	colA	-	-	-	-	-	-	-	-	-	-	-	BolA
SRR25158351_k127_368790_20	1206101.AZXC01000023_gene2986	1.79e-22	100.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_368790_24	2002.JOEQ01000017_gene7737	4.566e-10	69.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4EMFS@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_368790_11	1048339.KB913029_gene4857	3.177e-45	169.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4ES50@85013|Frankiales	201174|Actinobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_368790_12	1206101.AZXC01000023_gene2986	4.203e-43	162.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_368790_19	1206101.AZXC01000023_gene2987	1.635e-25	111.0	COG3795@1|root,COG3795@2|Bacteria,2GQ62@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158351_k127_368790_2	266117.Rxyl_2540	1.342e-201	649.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158351_k127_368790_4	76114.p2A386	3.09e-112	381.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VHE3@28216|Betaproteobacteria,2KYPH@206389|Rhodocyclales	206389|Rhodocyclales	IQ	AMP-binding enzyme	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_368790_22	66373.JOFQ01000001_gene1921	1.084e-18	88.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158351_k127_368790_10	386456.JQKN01000007_gene3251	3.134e-45	186.0	arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	csbC	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158351_k127_368790_21	67257.JODR01000048_gene384	2.284e-21	99.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158351_k127_368790_25	1206726.BAFV01000067_gene4613	6.298e-06	53.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4G1M8@85025|Nocardiaceae	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158351_k127_368790_7	469383.Cwoe_1322	3.656e-71	244.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158351_k127_368790_8	68223.JNZY01000017_gene1001	6.415e-56	199.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158351_k127_368790_5	469383.Cwoe_1324	1.055e-90	305.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158351_k127_368790_18	246194.CHY_2321	3.889e-28	121.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,42GM6@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158351_k127_368790_13	639282.DEFDS_1780	4.422e-37	143.0	COG0222@1|root,COG0222@2|Bacteria,2GFMS@200930|Deferribacteres	200930|Deferribacteres	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158351_k127_368790_15	1047013.AQSP01000062_gene1209	9.746e-32	142.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	XK27_02215	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5
SRR25158351_k127_368790_9	457425.XNR_3886	2.891e-49	180.0	COG0346@1|root,COG0346@2|Bacteria,2IFBN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_368790_1	269800.Tfu_2654	0.0	1313.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4EFYQ@85012|Streptosporangiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158351_k127_368790_0	469383.Cwoe_1328	0.0	1595.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CP97@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158351_k127_38835_4	1121406.JAEX01000016_gene1886	1.883e-14	84.0	2AEMU@1|root,314HR@2|Bacteria,1PU7I@1224|Proteobacteria,433G9@68525|delta/epsilon subdivisions,2WXVP@28221|Deltaproteobacteria,2MFQE@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_38835_5	463191.SSEG_02669	4.788e-13	82.0	COG2091@1|root,COG2091@2|Bacteria,2IQ65@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158351_k127_38835_0	56107.Cylst_4027	1.79e-185	612.0	COG0318@1|root,COG3319@1|root,COG0318@2|Bacteria,COG3319@2|Bacteria,1G3MS@1117|Cyanobacteria,1HIUD@1161|Nostocales	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
SRR25158351_k127_38835_2	398767.Glov_1521	9.942e-36	155.0	COG0463@1|root,COG0463@2|Bacteria,1RFXT@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
SRR25158351_k127_38835_3	395019.Bmul_5449	3.806e-20	100.0	COG2120@1|root,COG2120@2|Bacteria,1RI1F@1224|Proteobacteria,2VSXD@28216|Betaproteobacteria,1K4SZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_38835_1	1123248.KB893370_gene5111	8.494e-59	212.0	COG1216@1|root,COG1216@2|Bacteria,4PNIX@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_402539_4	42256.RradSPS_0416	6.227e-14	74.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158351_k127_402539_2	266117.Rxyl_1116	4.481e-60	219.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158351_k127_402539_0	1713.JOFV01000009_gene296	1.457e-91	317.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4F0X5@85016|Cellulomonadaceae	201174|Actinobacteria	C	amino acid-binding ACT domain protein	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158351_k127_402539_5	471853.Bcav_1186	0.0001038	54.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158351_k127_402539_1	1229780.BN381_10190	7.242e-71	250.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158351_k127_402539_3	1380390.JIAT01000009_gene2200	4.692e-17	85.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4CP6B@84995|Rubrobacteria	84995|Rubrobacteria	M	RmlD substrate binding domain	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158351_k127_410060_1	504728.K649_09305	3.602e-84	301.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158351_k127_410060_5	1122214.AQWH01000009_gene2033	2.348e-37	149.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2U9QR@28211|Alphaproteobacteria,2PK4S@255475|Aurantimonadaceae	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	MA20_05350	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_410060_2	1440053.JOEI01000001_gene1703	5.008e-69	243.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase,RraA-like
SRR25158351_k127_410060_6	368407.Memar_0174	7.599e-30	126.0	COG0558@1|root,arCOG00670@2157|Archaea,2XZF4@28890|Euryarchaeota,2NAXZ@224756|Methanomicrobia	224756|Methanomicrobia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.39,2.7.8.5	ko:K00995,ko:K17884	ko00564,ko01100,map00564,map01100	-	R01801,R10464	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_410060_3	469383.Cwoe_0789	9.447e-49	199.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158351_k127_410060_4	469383.Cwoe_0788	5.062e-47	183.0	COG1573@1|root,COG1573@2|Bacteria,2HNTA@201174|Actinobacteria,4CQ1J@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158351_k127_410060_0	1283299.AUKG01000001_gene1484	2.036e-101	351.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CRR6@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158351_k127_415158_2	1485544.JQKP01000001_gene1154	5.148e-42	160.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,44W3P@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158351_k127_415158_3	1304275.C41B8_13395	4.604e-34	141.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158351_k127_415158_4	365044.Pnap_2298	0.000149	53.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,4AF2I@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_415158_0	1122611.KB903952_gene6150	2.505e-97	322.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4EFI4@85012|Streptosporangiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158351_k127_415158_1	1380347.JNII01000005_gene3084	9.466e-47	183.0	COG3673@1|root,COG3673@2|Bacteria,2ID7N@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
SRR25158351_k127_420889_2	1313172.YM304_38280	1.893e-91	315.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CNT1@84992|Acidimicrobiia	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_420889_0	1313172.YM304_38290	7.27e-118	407.0	COG0577@1|root,COG0577@2|Bacteria,2GMC4@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	hrtB	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_420889_1	1313172.YM304_38300	2.954e-105	355.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158351_k127_420889_5	234267.Acid_0856	6.208e-19	100.0	COG3391@1|root,COG3391@2|Bacteria,3Y5TX@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158351_k127_420889_7	1352941.M877_26675	0.0004793	45.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158351_k127_420889_4	404589.Anae109_4300	2.751e-29	118.0	COG0599@1|root,COG0599@2|Bacteria,1RK66@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_420889_3	1232410.KI421428_gene1084	5.348e-44	170.0	COG0491@1|root,COG0491@2|Bacteria,1NMU0@1224|Proteobacteria,432WR@68525|delta/epsilon subdivisions,2WY8W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
SRR25158351_k127_420889_6	404589.Anae109_4238	5.297e-06	53.0	COG2030@1|root,COG2030@2|Bacteria,1RJN8@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158351_k127_421584_4	469383.Cwoe_1170	4.215e-24	113.0	2B09U@1|root,31SKS@2|Bacteria,2HUBE@201174|Actinobacteria,4CU0W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_421584_2	44060.JODL01000031_gene1717	2e-81	278.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_421584_7	101510.RHA1_ro00019	6.976e-16	79.0	2EMYX@1|root,33FM2@2|Bacteria,2GZ6D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_421584_8	1463885.KL578401_gene7401	2.956e-09	64.0	2ATIE@1|root,31J2A@2|Bacteria,2IISG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_421584_5	1380354.JIAN01000010_gene2991	6.29e-19	93.0	COG4803@1|root,COG4803@2|Bacteria,2I7QR@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158351_k127_421584_3	1089544.KB912942_gene1307	5.298e-60	219.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4DXV2@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_421584_0	1122622.ATWJ01000015_gene659	2.843e-296	934.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4FFQQ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158351_k127_421584_1	469383.Cwoe_5163	1.49e-151	507.0	28IC5@1|root,2Z8EI@2|Bacteria,2IA7M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_421584_6	1094980.Mpsy_0339	1.909e-16	84.0	COG1226@1|root,arCOG01958@2157|Archaea,2Y1ZP@28890|Euryarchaeota,2NA44@224756|Methanomicrobia	224756|Methanomicrobia	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158351_k127_421584_9	1288083.AUKR01000005_gene2338	1.657e-06	59.0	COG1289@1|root,COG1289@2|Bacteria,2GN5P@201174|Actinobacteria	201174|Actinobacteria	S	membrane	yccS_3	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
SRR25158351_k127_422679_0	1121106.JQKB01000078_gene3666	2.123e-96	329.0	COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,2U21F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Abhydrolase_6,Hydrolase_4,Peptidase_S15
SRR25158351_k127_422679_5	95619.PM1_0216875	1.742e-08	63.0	COG3631@1|root,COG3631@2|Bacteria,1RFEA@1224|Proteobacteria,1S5QQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158351_k127_422679_4	1380390.JIAT01000013_gene152	2.229e-19	96.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4CRY0@84995|Rubrobacteria	84995|Rubrobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_422679_2	1125971.ASJB01000031_gene1283	5.782e-47	181.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,4E3BW@85010|Pseudonocardiales	201174|Actinobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158351_k127_422679_3	994479.GL877878_gene1245	1.197e-39	162.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4E3JE@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158351_k127_422679_1	1278078.G419_01445	3.425e-71	253.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4FVTX@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the FPG family	nei1	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K05522,ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158351_k127_43562_6	1283299.AUKG01000001_gene1317	3.46e-25	110.0	COG0546@1|root,COG0546@2|Bacteria,2HQRV@201174|Actinobacteria,4CSFD@84995|Rubrobacteria	84995|Rubrobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_43562_5	1380390.JIAT01000010_gene4861	5.251e-33	133.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4CQN1@84995|Rubrobacteria	84995|Rubrobacteria	M	Large-conductance mechanosensitive channel, MscL	-	-	-	-	-	-	-	-	-	-	-	-	MscL
SRR25158351_k127_43562_3	326424.FRAAL5059	3.519e-63	224.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria	201174|Actinobacteria	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158351_k127_43562_7	246197.MXAN_5220	4.496e-10	73.0	COG0122@1|root,COG5483@1|root,COG0122@2|Bacteria,COG5483@2|Bacteria,1PERA@1224|Proteobacteria,435TA@68525|delta/epsilon subdivisions,2X08G@28221|Deltaproteobacteria,2Z18M@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158351_k127_43562_2	570967.JMLV01000019_gene393	1.132e-92	313.0	COG0388@1|root,COG0388@2|Bacteria,1RIQI@1224|Proteobacteria,2VA96@28211|Alphaproteobacteria,2JV1D@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158351_k127_43562_4	469383.Cwoe_4041	1.253e-55	211.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158351_k127_43562_1	926566.Terro_4363	5.199e-98	330.0	COG0258@1|root,COG0258@2|Bacteria,3Y2FG@57723|Acidobacteria,2JME1@204432|Acidobacteriia	204432|Acidobacteriia	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158351_k127_43562_0	526225.Gobs_2962	1.183e-110	373.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158351_k127_440020_1	1304275.C41B8_11633	1.655e-62	224.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158351_k127_440020_0	351607.Acel_1697	2.769e-203	651.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria,4ES7V@85013|Frankiales	201174|Actinobacteria	I	Squalene--hopene cyclase	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
SRR25158351_k127_440020_2	67332.FM21_16655	2.718e-59	215.0	COG1562@1|root,COG1562@2|Bacteria,2GNS9@201174|Actinobacteria	201174|Actinobacteria	I	Squalene phytoene synthase	hopE	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR25158351_k127_443693_1	1283299.AUKG01000002_gene3889	7.76e-73	258.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158351_k127_443693_0	1009370.ALO_09969	5.364e-213	670.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4H2IA@909932|Negativicutes	909932|Negativicutes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158351_k127_443693_4	1408424.JHYI01000015_gene4731	2.312e-19	93.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158351_k127_443693_2	1123269.NX02_25690	1.625e-51	198.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TSHC@28211|Alphaproteobacteria,2K0UX@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158351_k127_443693_3	469383.Cwoe_4616	6.278e-51	187.0	COG0624@1|root,COG0624@2|Bacteria,2I9GD@201174|Actinobacteria,4CPM7@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_452328_9	1288298.rosmuc_02195	8.413e-07	57.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46P0R@74030|Roseovarius	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
SRR25158351_k127_452328_1	1283299.AUKG01000002_gene5010	1.062e-45	183.0	28MY8@1|root,32YD0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_452328_3	469383.Cwoe_1170	1.356e-17	96.0	2B09U@1|root,31SKS@2|Bacteria,2HUBE@201174|Actinobacteria,4CU0W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_452328_10	1411123.JQNH01000001_gene1558	5.235e-05	51.0	COG0500@1|root,COG2226@2|Bacteria,1RCDB@1224|Proteobacteria,2VF9E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_452328_4	1206735.BAGG01000054_gene2207	5.289e-13	72.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria,4G4QR@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158351_k127_452328_0	298653.Franean1_5625	2.016e-65	232.0	COG2898@1|root,COG2898@2|Bacteria,2I31G@201174|Actinobacteria,4EXDC@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF2156,tRNA-synt_2_TM
SRR25158351_k127_452328_8	156978.CIMIT_05530	4.346e-07	54.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,22RHK@1653|Corynebacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int8	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158351_k127_452328_7	1048339.KB913029_gene1684	1.552e-07	59.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESP4@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158351_k127_452328_2	518766.Rmar_1089	2.59e-21	97.0	COG0286@1|root,COG0286@2|Bacteria,4NG0E@976|Bacteroidetes,1FJK2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR25158351_k127_452328_6	742725.HMPREF9450_01569	1.025e-07	63.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,4PKEU@976|Bacteroidetes,2FKZ0@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
SRR25158351_k127_454790_8	929712.KI912613_gene4768	3.237e-34	138.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158351_k127_454790_2	1124780.ANNU01000019_gene1715	1.364e-78	280.0	COG1363@1|root,COG1363@2|Bacteria,4NIW2@976|Bacteroidetes,47JPS@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158351_k127_454790_10	1499680.CCFE01000023_gene2472	1.072e-13	84.0	COG4193@1|root,COG4193@2|Bacteria,1TSZR@1239|Firmicutes,4HDB1@91061|Bacilli,1ZG06@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
SRR25158351_k127_454790_5	518766.Rmar_2512	9.176e-37	147.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1FK0J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158351_k127_454790_6	1283299.AUKG01000002_gene5113	2.066e-36	149.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_454790_3	1313172.YM304_31130	4.849e-54	202.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria	201174|Actinobacteria	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_454790_0	929712.KI912613_gene2740	1.36e-119	392.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_454790_11	358220.C380_21800	3.503e-10	66.0	COG1734@1|root,COG1734@2|Bacteria,1NA1P@1224|Proteobacteria,2VX46@28216|Betaproteobacteria,4AFF7@80864|Comamonadaceae	28216|Betaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158351_k127_454790_4	1306406.ASHX01000002_gene5198	1.044e-40	169.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria	201174|Actinobacteria	D	Ribonuclease bn	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158351_k127_454790_1	429009.Adeg_1192	3.332e-109	362.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,24GKF@186801|Clostridia,42HT2@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_454790_7	298655.KI912267_gene7019	2.102e-34	147.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4ESN0@85013|Frankiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158351_k127_454790_9	479435.Kfla_4172	2.341e-25	121.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4DPE5@85009|Propionibacteriales	201174|Actinobacteria	P	CopC domain	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158351_k127_472455_0	471852.Tcur_3261	2.467e-232	732.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4EGDX@85012|Streptosporangiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158351_k127_472455_7	1313172.YM304_21150	1.002e-65	239.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_472455_4	469383.Cwoe_2842	5.668e-96	325.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CP6H@84995|Rubrobacteria	84995|Rubrobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158351_k127_472455_15	1463855.JOHV01000001_gene1653	1.895e-17	88.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158351_k127_472455_3	469383.Cwoe_2843	1.27e-105	354.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CP6R@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_472455_11	469383.Cwoe_2844	2.363e-45	176.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158351_k127_472455_12	1502852.FG94_02474	1.203e-28	126.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,472R6@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158351_k127_472455_2	469383.Cwoe_2849	2.9e-120	396.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158351_k127_472455_14	1122939.ATUD01000002_gene1435	8.886e-22	102.0	COG0319@1|root,COG0319@2|Bacteria,2HN3K@201174|Actinobacteria,4CQHV@84995|Rubrobacteria	84995|Rubrobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158351_k127_472455_9	293826.Amet_3030	4.665e-52	195.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,36DSP@31979|Clostridiaceae	186801|Clostridia	IM	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
SRR25158351_k127_472455_5	469383.Cwoe_2851	7.86e-74	260.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158351_k127_472455_10	469383.Cwoe_1111	7.245e-47	182.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4CPDC@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158351_k127_472455_13	580327.Tthe_1201	1.198e-22	108.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,42FFH@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158351_k127_472455_8	1123489.AUAN01000004_gene1791	5.601e-57	206.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4H2VN@909932|Negativicutes	909932|Negativicutes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158351_k127_472455_1	469383.Cwoe_2853	3.709e-147	483.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158351_k127_472455_6	479434.Sthe_1877	2.992e-73	258.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158351_k127_473491_0	1043493.BBLU01000006_gene2226	4.608e-47	189.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	ycnJ	-	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD
SRR25158351_k127_473491_1	1136417.AZWE01000018_gene1002	1.104e-30	126.0	COG0477@1|root,COG0477@2|Bacteria,2IAI1@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_473491_3	645465.ACUR01000675_gene5521	2.506e-07	61.0	COG0477@1|root,COG0477@2|Bacteria,2GKUK@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_473491_2	710685.MycrhN_0724	1.95e-13	78.0	COG0477@1|root,COG0477@2|Bacteria,2IAI1@201174|Actinobacteria,2370X@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_491196_18	1122939.ATUD01000002_gene1444	3.467e-29	128.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_491196_10	477974.Daud_1419	8.768e-71	246.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_491196_12	1379270.AUXF01000003_gene3567	9.284e-52	205.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158351_k127_491196_16	714943.Mucpa_3445	5.692e-35	151.0	COG1028@1|root,COG1028@2|Bacteria,4PN8P@976|Bacteroidetes,1J0P4@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_491196_7	123899.JPQP01000022_gene3504	2.396e-94	325.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,2VK3Q@28216|Betaproteobacteria,3T2YY@506|Alcaligenaceae	28216|Betaproteobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158351_k127_491196_2	1380390.JIAT01000009_gene2057	5.538e-150	485.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CPTQ@84995|Rubrobacteria	84995|Rubrobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158351_k127_491196_4	330214.NIDE3015	2.983e-115	397.0	COG1088@1|root,COG1088@2|Bacteria,3J0CT@40117|Nitrospirae	40117|Nitrospirae	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158351_k127_491196_11	1341151.ASZU01000008_gene1481	3.885e-66	239.0	COG1207@1|root,COG1207@2|Bacteria,1UIKN@1239|Firmicutes,4HC88@91061|Bacilli,27B78@186824|Thermoactinomycetaceae	91061|Bacilli	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158351_k127_491196_6	1379698.RBG1_1C00001G1537	1.256e-94	322.0	COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,Hexapep,Hexapep_2
SRR25158351_k127_491196_0	1278073.MYSTI_03091	1.127e-158	512.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria,2YTWM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158351_k127_491196_3	469383.Cwoe_5917	6.419e-118	391.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CTCM@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158351_k127_491196_5	530564.Psta_4026	1.53e-114	387.0	COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158351_k127_491196_1	595460.RRSWK_00977	4.987e-153	495.0	COG1830@1|root,COG1830@2|Bacteria,2IWUP@203682|Planctomycetes	203682|Planctomycetes	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158351_k127_491196_13	1037409.BJ6T_61140	1.763e-40	163.0	COG1225@1|root,COG1225@2|Bacteria,1NWRG@1224|Proteobacteria,2TY94@28211|Alphaproteobacteria,3JWAM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158351_k127_491196_19	1122939.ATUD01000006_gene1661	2.555e-17	94.0	COG2723@1|root,COG2723@2|Bacteria,2HNUQ@201174|Actinobacteria,4CQ33@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_491196_14	1047013.AQSP01000062_gene1209	1.565e-35	156.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	XK27_02215	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5
SRR25158351_k127_491196_8	536019.Mesop_2093	4.075e-83	286.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2UQUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
SRR25158351_k127_491196_9	134676.ACPL_3123	7.51e-77	270.0	COG0022@1|root,COG0022@2|Bacteria,2I8HH@201174|Actinobacteria,4DDH8@85008|Micromonosporales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
SRR25158351_k127_491196_17	243231.GSU3020	2.583e-32	141.0	COG0508@1|root,COG2171@1|root,COG0508@2|Bacteria,COG2171@2|Bacteria,1QV0Z@1224|Proteobacteria,43BNF@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158351_k127_491196_15	1121439.dsat_1722	2.717e-35	148.0	28HYD@1|root,2Z83U@2|Bacteria,1R5TY@1224|Proteobacteria,43104@68525|delta/epsilon subdivisions,2WWF8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158351_k127_497831_3	469383.Cwoe_0790	5.925e-49	183.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CQZJ@84995|Rubrobacteria	84995|Rubrobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158351_k127_497831_5	196162.Noca_1088	3.41e-25	113.0	COG1961@1|root,COG1961@2|Bacteria,2INCR@201174|Actinobacteria,4DWU7@85009|Propionibacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
SRR25158351_k127_497831_9	929712.KI912613_gene2690	1.301e-11	68.0	2AUU5@1|root,31KH9@2|Bacteria,2HPC7@201174|Actinobacteria,4CQQB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_497831_6	1229780.BN381_630015	1.039e-22	107.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,3UWSU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158351_k127_497831_11	1380390.JIAT01000009_gene717	0.0008324	47.0	COG2919@1|root,COG2919@2|Bacteria,2HRMQ@201174|Actinobacteria,4CTPQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158351_k127_497831_1	1089553.Tph_c06780	1.299e-171	552.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,42ER3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158351_k127_497831_2	469383.Cwoe_5239	3.214e-53	202.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CQXI@84995|Rubrobacteria	84995|Rubrobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
SRR25158351_k127_497831_4	266117.Rxyl_0911	7.388e-28	128.0	COG0760@1|root,COG0760@2|Bacteria,2IGXV@201174|Actinobacteria,4CU3I@84995|Rubrobacteria	84995|Rubrobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	SurA_N_3
SRR25158351_k127_497831_8	298654.FraEuI1c_3723	1.217e-15	85.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_497831_10	1077144.AGFF01000007_gene1695	2.742e-07	57.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158351_k127_497831_0	469383.Cwoe_5241	7.753e-202	642.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158351_k127_532560_10	1206725.BAFU01000039_gene1950	1.149e-13	82.0	2B2T9@1|root,31VDM@2|Bacteria,2HWS3@201174|Actinobacteria,4FZIF@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_532560_9	237368.SCABRO_01410	6.301e-14	81.0	COG0778@1|root,COG0778@2|Bacteria,2J2XW@203682|Planctomycetes	203682|Planctomycetes	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
SRR25158351_k127_532560_6	208439.AJAP_24890	3.931e-44	164.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4E60Z@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_532560_1	2074.JNYD01000012_gene347	8.109e-98	347.0	COG0745@1|root,COG1672@1|root,COG2197@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,COG2197@2|Bacteria	2|Bacteria	K	response regulator	fruA	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_532560_11	2074.JNYD01000012_gene348	2.635e-12	73.0	2BAK4@1|root,3240W@2|Bacteria,2H8T3@201174|Actinobacteria	201174|Actinobacteria	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
SRR25158351_k127_532560_4	1449346.JQMO01000002_gene1700	7.472e-48	175.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158351_k127_532560_5	215803.DB30_0185	3.337e-47	183.0	COG2227@1|root,COG2227@2|Bacteria,1REBU@1224|Proteobacteria,43AGQ@68525|delta/epsilon subdivisions,2X5WI@28221|Deltaproteobacteria,2Z37B@29|Myxococcales	28221|Deltaproteobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_532560_7	1713.JOFV01000001_gene1918	1.425e-38	146.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4F2PF@85016|Cellulomonadaceae	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158351_k127_532560_3	1121403.AUCV01000007_gene1193	3.106e-62	221.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2MJU9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158351_k127_532560_0	357808.RoseRS_4459	3.248e-115	392.0	COG1139@1|root,COG1139@2|Bacteria,2G665@200795|Chloroflexi,37659@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
SRR25158351_k127_532560_12	760568.Desku_2394	2.287e-10	70.0	COG1556@1|root,COG1556@2|Bacteria,1VATZ@1239|Firmicutes,24P3S@186801|Clostridia,262FK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158351_k127_532560_13	56110.Oscil6304_3353	0.0009007	49.0	COG1357@1|root,COG1357@2|Bacteria,1G02C@1117|Cyanobacteria,1H8G5@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158351_k127_532560_2	314278.NB231_00635	1.803e-90	306.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,1SE87@1236|Gammaproteobacteria,1WZJ6@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158351_k127_532560_8	590998.Celf_1894	1.639e-31	136.0	28NWQ@1|root,2ZBUI@2|Bacteria,2IGY4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_537365_3	1122223.KB890700_gene2024	1.45e-38	159.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbdA	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_537365_1	479434.Sthe_1714	3.362e-46	181.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,27XSF@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_537365_2	1128421.JAGA01000002_gene1655	2.249e-39	164.0	COG0438@1|root,COG0438@2|Bacteria,2NR3F@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_537365_0	929712.KI912613_gene479	2.49e-92	310.0	COG0438@1|root,COG0438@2|Bacteria,2IBM0@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_545428_6	429009.Adeg_0447	2.818e-12	69.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158351_k127_545428_5	587753.EY04_13765	3.284e-14	86.0	COG0477@1|root,COG0477@2|Bacteria,1MX9T@1224|Proteobacteria,1RY2X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_545428_3	1306990.BARG01000033_gene3748	1.148e-19	95.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_545428_0	243274.THEMA_08145	9.942e-133	450.0	COG0210@1|root,COG0210@2|Bacteria,2GC9X@200918|Thermotogae	200918|Thermotogae	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158351_k127_545428_2	298654.FraEuI1c_3132	5.115e-31	132.0	arCOG12117@1|root,2Z9N1@2|Bacteria,2GTM3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
SRR25158351_k127_545428_4	224911.27353627	5.49e-19	89.0	COG0659@1|root,COG3360@1|root,COG0659@2|Bacteria,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158351_k127_545428_7	709986.Deima_1063	1.645e-07	62.0	COG4328@1|root,COG4328@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
SRR25158351_k127_545428_1	1380391.JIAS01000013_gene3563	3.046e-41	163.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,2JZ13@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_545428_8	1306406.ASHX01000001_gene3114	0.0009251	51.0	COG0265@1|root,COG0265@2|Bacteria,2GJ15@201174|Actinobacteria	201174|Actinobacteria	O	PDZ DHR GLGF domain protein	sprJ	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_546687_0	1229780.BN381_180017	3.371e-63	239.0	2CFVH@1|root,344CD@2|Bacteria,2H8C6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_546687_2	477641.MODMU_5370	5.093e-44	166.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria,4EWF6@85013|Frankiales	201174|Actinobacteria	P	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_546687_1	319795.Dgeo_2559	1.129e-57	210.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_3,DUF4396
SRR25158351_k127_546687_4	195253.Syn6312_2119	1.932e-20	92.0	COG5031@1|root,COG5031@2|Bacteria,1GMZC@1117|Cyanobacteria,1H029@1129|Synechococcus	1117|Cyanobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_550864_3	1298880.AUEV01000005_gene987	3.286e-72	254.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_550864_0	479432.Sros_0040	3.278e-106	354.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EGX2@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_550864_5	469383.Cwoe_2985	6.068e-54	192.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_550864_4	543632.JOJL01000035_gene5070	7.833e-55	218.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158351_k127_550864_6	1195236.CTER_3452	1.498e-30	132.0	COG2120@1|root,COG2120@2|Bacteria,1V145@1239|Firmicutes,24FD4@186801|Clostridia,3WNSI@541000|Ruminococcaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158351_k127_550864_7	247156.NFA_7870	3.371e-20	103.0	COG0500@1|root,COG2226@2|Bacteria,2IP2P@201174|Actinobacteria,4G8M3@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_550864_9	1155714.KB891994_gene4894	0.0008329	48.0	COG0494@1|root,COG0494@2|Bacteria,2IKSQ@201174|Actinobacteria	201174|Actinobacteria	L	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,NYN_YacP
SRR25158351_k127_550864_2	710686.Mycsm_01585	7.5e-73	252.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,2335S@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_550864_1	246194.CHY_1144	4.407e-87	307.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42F1S@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRR25158351_k127_55468_6	469383.Cwoe_1298	1.014e-35	149.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_55468_12	1038866.KB902770_gene4338	0.0003891	51.0	COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,2TQTS@28211|Alphaproteobacteria,3JSWF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KLT	Serine threonine protein kinase	MA20_09295	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Usp
SRR25158351_k127_55468_0	232721.Ajs_2162	8.675e-271	857.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,2VK07@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glycosyl hydrolase family 65 central catalytic domain protein	-	-	2.4.1.64,2.4.1.8	ko:K00691,ko:K05342	ko00500,ko01100,map00500,map01100	-	R01555,R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158351_k127_55468_1	196162.Noca_0969	3.106e-183	602.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_55468_3	298653.Franean1_4336	8.664e-92	313.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_55468_10	29306.JOBE01000042_gene5121	3.416e-12	68.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_55468_8	104623.Ser39006_02075	6.587e-20	103.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,1SA74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_55468_5	28258.KP05_01470	5.987e-42	170.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,1XP3R@135619|Oceanospirillales	135619|Oceanospirillales	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158351_k127_55468_11	929712.KI912613_gene2298	3.175e-05	51.0	28TIQ@1|root,2ZFSJ@2|Bacteria,2I6IR@201174|Actinobacteria,4CSHG@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_55468_7	1449346.JQMO01000003_gene5992	6.039e-23	104.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,2M3NK@2063|Kitasatospora	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_55468_4	1240349.ANGC01000033_gene2993	1.58e-78	278.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4G023@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158351_k127_55468_2	1283299.AUKG01000004_gene906	4.335e-114	391.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4CPPW@84995|Rubrobacteria	84995|Rubrobacteria	P	sulphate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158351_k127_55468_9	339670.Bamb_6408	6.335e-16	89.0	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,2VT4I@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	-	-	-	ko:K04033	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158351_k127_585385_4	593907.Celgi_2252	8.278e-11	70.0	COG4978@1|root,COG4978@2|Bacteria,2IQMV@201174|Actinobacteria	201174|Actinobacteria	KT	Transcriptional regulator, effector-binding domain component	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR25158351_k127_585385_3	1120946.AUBF01000006_gene420	3.709e-15	89.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4D3ZG@85005|Actinomycetales	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158351_k127_585385_2	1123267.JONN01000002_gene358	1.694e-47	179.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2K3VU@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158351_k127_585385_0	1283299.AUKG01000001_gene2249	1.602e-95	323.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4CRA0@84995|Rubrobacteria	84995|Rubrobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158351_k127_585385_1	477641.MODMU_1241	4.36e-95	324.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4EU45@85013|Frankiales	201174|Actinobacteria	M	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158351_k127_585385_5	1380390.JIAT01000011_gene2703	6.689e-05	49.0	COG4464@1|root,COG4464@2|Bacteria,2H0WF@201174|Actinobacteria,4CSZY@84995|Rubrobacteria	84995|Rubrobacteria	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158351_k127_58936_10	653045.Strvi_1182	1.275e-08	62.0	COG0346@1|root,COG0346@2|Bacteria,2IS2C@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_58936_0	1445613.JALM01000015_gene5651	4.289e-202	647.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4E1U7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6,2.5.1.66	ko:K01652,ko:K12673	ko00290,ko00331,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00331,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570,M00674	R00006,R00014,R00226,R03050,R04672,R04673,R05465,R08648	RC00027,RC00106,RC00215,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_58936_6	306281.AJLK01000152_gene2099	5.039e-19	95.0	COG4803@1|root,COG4803@2|Bacteria,1GA6S@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158351_k127_58936_2	1121946.AUAX01000004_gene965	1.881e-95	328.0	28KUD@1|root,2ZAB6@2|Bacteria,2IACK@201174|Actinobacteria,4D94P@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_58936_7	1298863.AUEP01000005_gene2687	4.558e-16	85.0	2C4JJ@1|root,32RE3@2|Bacteria,2IKF1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158351_k127_58936_1	1380370.JIBA01000013_gene1327	1.196e-138	461.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4FG51@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158351_k127_58936_8	1463900.JOIX01000003_gene865	3.84e-12	72.0	COG1597@1|root,COG1597@2|Bacteria,2GNNM@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158351_k127_58936_3	1379270.AUXF01000003_gene3384	1.087e-90	315.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158351_k127_58936_4	166318.Syn8016DRAFT_1065	1.163e-48	184.0	COG0524@1|root,COG0524@2|Bacteria,1GBJ2@1117|Cyanobacteria,1GYYZ@1129|Synechococcus	1117|Cyanobacteria	G	pfkB family carbohydrate kinase	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_621493_0	1283299.AUKG01000001_gene1281	2.151e-274	874.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
SRR25158351_k127_623695_2	469383.Cwoe_3480	8.328e-168	545.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158351_k127_623695_8	1403313.AXBR01000003_gene4034	2.676e-43	179.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZEFV@1386|Bacillus	91061|Bacilli	O	Subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158351_k127_623695_11	469383.Cwoe_4908	7.383e-20	96.0	COG2350@1|root,COG2350@2|Bacteria,2GU13@201174|Actinobacteria,4CTYH@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRR25158351_k127_623695_4	1210046.B277_00905	3.318e-90	311.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4FEM0@85021|Intrasporangiaceae	201174|Actinobacteria	BQ	acetoin utilization protein	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158351_k127_623695_10	1223542.GM1_011_01000	4.52e-27	119.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4GBEI@85026|Gordoniaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158351_k127_623695_7	582515.KR51_00026840	4.793e-46	175.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158351_k127_623695_1	479434.Sthe_2436	1.807e-178	573.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158351_k127_623695_0	1123368.AUIS01000001_gene1896	8.245e-218	695.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,2NDRU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158351_k127_623695_3	926569.ANT_08520	3.185e-139	457.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158351_k127_623695_14	42256.RradSPS_1193	1.909e-14	83.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K01420,ko:K10914,ko:K21561	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158351_k127_623695_6	309807.SRU_2045	7.225e-55	203.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,4NGUP@976|Bacteroidetes,1FK7U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	FeoA	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158351_k127_623695_12	1283299.AUKG01000002_gene4161	3.57e-17	86.0	2BR6D@1|root,31ZND@2|Bacteria,2HRCI@201174|Actinobacteria,4CTA1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_623695_5	314230.DSM3645_08502	1.503e-89	308.0	COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
SRR25158351_k127_623695_9	1403819.BATR01000067_gene2008	3.132e-43	161.0	COG0662@1|root,COG0662@2|Bacteria,46VA6@74201|Verrucomicrobia,2IVWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158351_k127_623695_13	626939.HMPREF9443_01815	2.846e-16	84.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,4H4QB@909932|Negativicutes	909932|Negativicutes	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_623695_15	469383.Cwoe_4476	8.668e-11	66.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158351_k127_631626_2	1283300.ATXB01000001_gene444	4e-57	215.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,1XDYA@135618|Methylococcales	135618|Methylococcales	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158351_k127_631626_0	247634.GPB2148_2450	9.879e-73	262.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,1SFAP@1236|Gammaproteobacteria,1JAZV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158351_k127_631626_4	1207058.L53_09380	1.974e-14	79.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2TRC6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158351_k127_631626_1	1273125.Rrhod_2250	1.454e-69	249.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4FVTX@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the FPG family	nei1	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K05522,ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158351_k127_631626_5	1118235.CAJH01000031_gene2100	0.0008175	45.0	COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,1RNBQ@1236|Gammaproteobacteria,1X53C@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_631626_3	1380356.JNIK01000014_gene3260	2.28e-16	85.0	2BKUK@1|root,32FAZ@2|Bacteria,2GZ3J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_636964_6	1121937.AUHJ01000002_gene3612	8.126e-28	118.0	COG3467@1|root,COG3467@2|Bacteria,1N17U@1224|Proteobacteria,1SA1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158351_k127_636964_4	1229780.BN381_40030	1.838e-42	160.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_636964_5	324057.Pjdr2_5636	1.575e-34	146.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,26QIW@186822|Paenibacillaceae	91061|Bacilli	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158351_k127_636964_9	698758.AXY_19320	3.315e-18	95.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli	91061|Bacilli	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158351_k127_636964_2	309801.trd_A0009	4.977e-59	210.0	COG1335@1|root,COG1335@2|Bacteria,2G6JY@200795|Chloroflexi	200795|Chloroflexi	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158351_k127_636964_0	1158182.KB905022_gene1161	7.314e-119	398.0	COG1488@1|root,COG1488@2|Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
SRR25158351_k127_636964_10	1172188.KB911824_gene3347	9.996e-12	70.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria,4FK1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR25158351_k127_636964_11	1206735.BAGG01000019_gene805	2.287e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4FVZ0@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158351_k127_636964_3	469383.Cwoe_0007	4.931e-50	183.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CQBX@84995|Rubrobacteria	84995|Rubrobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158351_k127_636964_1	290397.Adeh_1779	4.244e-62	226.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2YV42@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158351_k127_636964_7	1283299.AUKG01000001_gene1754	2.819e-26	115.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4CS7C@84995|Rubrobacteria	84995|Rubrobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158351_k127_636964_8	1380390.JIAT01000009_gene1783	1.864e-18	96.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria,4CQ1U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_638834_20	4432.XP_010276268.1	0.0001562	45.0	COG0076@1|root,KOG1383@2759|Eukaryota,37T1T@33090|Viridiplantae,3GHR4@35493|Streptophyta	35493|Streptophyta	E	Belongs to the group II decarboxylase family	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158351_k127_638834_3	1158338.JNLJ01000001_gene371	5.317e-121	398.0	COG0136@1|root,COG0136@2|Bacteria,2G3QW@200783|Aquificae	200783|Aquificae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158351_k127_638834_1	1283299.AUKG01000003_gene505	1.387e-146	477.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CPEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158351_k127_638834_12	485916.Dtox_2356	5.715e-42	162.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
SRR25158351_k127_638834_15	246197.MXAN_6602	8.409e-28	126.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158351_k127_638834_18	471852.Tcur_2970	6.715e-07	61.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria,4EH8I@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
SRR25158351_k127_638834_0	1123024.AUII01000053_gene167	3.212e-154	499.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158351_k127_638834_17	694430.Natoc_0874	2.553e-09	64.0	COG0508@1|root,COG1765@1|root,arCOG01706@2157|Archaea,arCOG03686@2157|Archaea,2XTF5@28890|Euryarchaeota,23U77@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	dsa2	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding,OsmC
SRR25158351_k127_638834_7	756499.Desde_0782	4.137e-79	281.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia,262C0@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_638834_5	1123024.AUII01000034_gene2675	6.553e-91	318.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria,4E87Z@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158351_k127_638834_11	1489678.RDMS_11160	3.924e-42	172.0	COG0019@1|root,COG0019@2|Bacteria,1WISC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158351_k127_638834_9	1122132.AQYH01000004_gene1685	2.721e-63	229.0	COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria,4B9HI@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Catalyzes the desulfonation of aliphatic sulfonates	ssuD	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158351_k127_638834_16	383372.Rcas_3728	1.122e-20	107.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_638834_6	1219084.AP014508_gene692	6.824e-80	279.0	COG0549@1|root,COG0549@2|Bacteria,2GCB0@200918|Thermotogae	200918|Thermotogae	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158351_k127_638834_10	675635.Psed_1625	1.339e-62	220.0	COG2044@1|root,COG2044@2|Bacteria,2GJQS@201174|Actinobacteria,4DYQM@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158351_k127_638834_2	1123024.AUII01000005_gene2477	5.59e-127	411.0	COG2159@1|root,COG2159@2|Bacteria,2I9E4@201174|Actinobacteria,4E0Z3@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158351_k127_638834_4	1123024.AUII01000009_gene2056	1.009e-107	361.0	COG2516@1|root,COG2516@2|Bacteria,2GN07@201174|Actinobacteria,4E1DF@85010|Pseudonocardiales	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_638834_14	1123024.AUII01000034_gene2677	8.729e-29	123.0	COG2153@1|root,COG2153@2|Bacteria	2|Bacteria	K	protein acetylation	yyaT	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
SRR25158351_k127_638834_13	1123024.AUII01000028_gene2487	3.372e-38	155.0	COG2144@1|root,COG2144@2|Bacteria,2GM78@201174|Actinobacteria,4E1YB@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR synthase related protein, C-terminal domain	thiL_1	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10
SRR25158351_k127_638834_8	596152.DesU5LDRAFT_0342	6.427e-67	246.0	COG0074@1|root,COG0074@2|Bacteria,1MX67@1224|Proteobacteria,42YBN@68525|delta/epsilon subdivisions,2WUM1@28221|Deltaproteobacteria,2MAER@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
SRR25158351_k127_662152_3	56107.Cylst_6123	5.557e-37	152.0	COG1104@1|root,COG1104@2|Bacteria,1G0YB@1117|Cyanobacteria,1HISA@1161|Nostocales	1117|Cyanobacteria	E	Cysteine desulfurase	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158351_k127_662152_1	469383.Cwoe_4521	4.719e-59	213.0	COG0639@1|root,COG0639@2|Bacteria,2HNQI@201174|Actinobacteria,4CPX1@84995|Rubrobacteria	84995|Rubrobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158351_k127_662152_2	397278.JOJN01000004_gene1174	2.113e-53	206.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,4DPZ2@85009|Propionibacteriales	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158351_k127_662152_4	765912.Thimo_2598	2.396e-24	109.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1WY5P@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158351_k127_662152_0	1121929.KB898673_gene3994	6.426e-131	436.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,46ZRZ@74385|Gracilibacillus	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158351_k127_673484_24	43989.cce_3162	3.361e-05	54.0	COG2452@1|root,COG2452@2|Bacteria,1G1T5@1117|Cyanobacteria,3KIKB@43988|Cyanothece	1117|Cyanobacteria	L	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,Resolvase
SRR25158351_k127_673484_22	479434.Sthe_1360	9.832e-10	70.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi,27YB6@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158351_k127_673484_16	1122223.KB890696_gene430	5.524e-30	131.0	COG1409@1|root,COG1409@2|Bacteria,1WINK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158351_k127_673484_20	273068.TTE2781	1.258e-13	79.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,42GUD@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158351_k127_673484_13	929712.KI912613_gene545	5.608e-39	150.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_673484_14	42256.RradSPS_0738	8.674e-37	144.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158351_k127_673484_8	568816.Acin_2412	2.337e-115	388.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes	909932|Negativicutes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158351_k127_673484_2	469383.Cwoe_5915	1.59e-163	525.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CPAP@84995|Rubrobacteria	84995|Rubrobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158351_k127_673484_23	1160137.KB907307_gene4352	2.494e-05	55.0	2916S@1|root,2ZNTX@2|Bacteria,2HHWM@201174|Actinobacteria,4G1CW@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_673484_15	382464.ABSI01000005_gene1369	2.55e-34	137.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158351_k127_673484_19	670487.Ocepr_0598	5.006e-14	80.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C
SRR25158351_k127_673484_7	717605.Theco_3090	3.72e-116	387.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,26SBN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
SRR25158351_k127_673484_4	243159.AFE_2356	1.203e-146	476.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria,2NCHK@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158351_k127_673484_9	557598.LHK_03079	7.506e-94	321.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,2KPTV@206351|Neisseriales	206351|Neisseriales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158351_k127_673484_18	1298863.AUEP01000010_gene4436	6.448e-18	89.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158351_k127_673484_11	1489678.RDMS_06435	1.387e-60	220.0	COG0047@1|root,COG0047@2|Bacteria,1WICX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158351_k127_673484_0	266117.Rxyl_0996	3.059e-215	690.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158351_k127_673484_5	649764.HMPREF0762_00996	1.542e-140	467.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CV2M@84998|Coriobacteriia	84998|Coriobacteriia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
SRR25158351_k127_673484_10	194867.ALBQ01000004_gene3501	6.464e-79	276.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2K07H@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158351_k127_673484_12	1380390.JIAT01000009_gene1478	7.982e-45	175.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CQ5M@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158351_k127_673484_3	264732.Moth_2044	1.132e-149	491.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,42EZN@68295|Thermoanaerobacterales	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
SRR25158351_k127_673484_21	164757.Mjls_0936	3.785e-11	75.0	COG0265@1|root,COG0265@2|Bacteria,2IE8E@201174|Actinobacteria,2379Z@1762|Mycobacteriaceae	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,Trypsin_2
SRR25158351_k127_673484_6	670487.Ocepr_1994	4.055e-119	393.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158351_k127_673484_1	469383.Cwoe_1723	1.4e-203	674.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CRWU@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPase (P-type)	-	-	3.6.3.8	ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158351_k127_673484_17	469383.Cwoe_5772	3.031e-28	122.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria	201174|Actinobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158351_k127_69466_0	469383.Cwoe_1145	1.392e-127	420.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CPM3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158351_k127_69466_3	1122138.AQUZ01000080_gene5240	1.937e-18	89.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,4DRS0@85009|Propionibacteriales	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158351_k127_69466_5	1382315.JPOI01000001_gene1179	1.073e-09	65.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,1WGMX@129337|Geobacillus	91061|Bacilli	C	Cytochrome c	cccB	-	-	ko:K12263,ko:K13300	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SRR25158351_k127_69466_1	760568.Desku_2575	5.759e-48	179.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,261VQ@186807|Peptococcaceae	186801|Clostridia	S	Isoleucine patch superfamily enzyme, carbonic anhydrase acetyltransferase	PaaY	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158351_k127_69466_2	2074.JNYD01000042_gene2208	2.707e-41	175.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
SRR25158351_k127_69466_4	1217720.ALOX01000087_gene3033	2.673e-17	85.0	COG4427@1|root,COG4427@2|Bacteria,1R4EV@1224|Proteobacteria,2TRVP@28211|Alphaproteobacteria,2JWMB@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158351_k127_702649_2	999630.TUZN_0859	0.0009593	44.0	COG2084@1|root,arCOG00247@2157|Archaea	2157|Archaea	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	DUF1932,F420_oxidored,NAD_binding_11,NAD_binding_2
SRR25158351_k127_702649_1	882083.SacmaDRAFT_2597	6.699e-20	96.0	COG2353@1|root,COG2353@2|Bacteria,2HG6A@201174|Actinobacteria,4EC6Q@85010|Pseudonocardiales	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158351_k127_702649_0	1278073.MYSTI_00050	3.391e-35	137.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158351_k127_703903_1	67267.JNXT01000017_gene7225	5.009e-177	571.0	COG0535@1|root,COG0639@1|root,COG0535@2|Bacteria,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	4.3.1.30	ko:K13309	ko00523,ko01130,map00523,map01130	M00797	R08583	RC02360	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_14,Metallophos_2,Radical_SAM,SPASM
SRR25158351_k127_703903_3	530564.Psta_2908	2.734e-116	388.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158351_k127_703903_6	1278073.MYSTI_01989	4.443e-29	119.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2YVJ2@29|Myxococcales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_703903_4	1032480.MLP_04480	2.757e-62	224.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23,Methyltransf_25
SRR25158351_k127_703903_0	1380390.JIAT01000010_gene4426	0.0	1098.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CP98@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158351_k127_703903_2	266117.Rxyl_2882	2.124e-126	417.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CPRP@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158351_k127_703903_8	1869.MB27_12225	3.702e-10	67.0	COG0642@1|root,COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DI3Z@85008|Micromonosporales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,PAS_9,SpoIIE
SRR25158351_k127_703903_5	1283283.ATXA01000003_gene1547	1.065e-57	206.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_703903_7	1449044.JMLE01000028_gene260	2.897e-11	70.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,1WB4K@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_713151_0	469383.Cwoe_5899	3.39e-144	486.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158351_k127_713151_6	469383.Cwoe_5896	5.617e-36	150.0	COG1011@1|root,COG1011@2|Bacteria,2HPG7@201174|Actinobacteria,4CQUS@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158351_k127_713151_11	1445613.JALM01000004_gene4577	1.693e-12	72.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,4E5PE@85010|Pseudonocardiales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRR25158351_k127_713151_12	345341.KUTG_06445	3.599e-06	53.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4E6SR@85010|Pseudonocardiales	201174|Actinobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158351_k127_713151_10	525373.HMPREF0766_12043	4.439e-27	124.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158351_k127_713151_1	525904.Tter_1226	1.72e-116	387.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158351_k127_713151_3	298655.KI912266_gene1000	4.642e-60	229.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4EUA5@85013|Frankiales	201174|Actinobacteria	EGP	drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_713151_4	653045.Strvi_5139	1.402e-40	166.0	COG0477@1|root,COG2814@2|Bacteria,2I2P6@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	mdfA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_713151_2	1380390.JIAT01000010_gene4168	3.345e-79	276.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CQ1M@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158351_k127_713151_7	211114.JOEF01000017_gene3899	3.274e-35	139.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4E2X5@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM AhpC TSA family	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158351_k127_713151_9	930169.B5T_01073	1.328e-28	129.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1XJCK@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158351_k127_713151_8	926560.KE387027_gene412	5.018e-34	137.0	COG1247@1|root,COG1247@2|Bacteria,1WK8X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158351_k127_713151_5	469383.Cwoe_5907	8.664e-37	145.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_744242_8	478741.JAFS01000001_gene2148	2.264e-55	198.0	COG3253@1|root,COG3253@2|Bacteria,46SQD@74201|Verrucomicrobia,37GJ1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Chlorite dismutase	ywfI	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158351_k127_744242_2	886293.Sinac_5178	3.959e-123	411.0	COG4284@1|root,COG4284@2|Bacteria,2IX7M@203682|Planctomycetes	203682|Planctomycetes	G	UDP-glucose pyrophosphorylase	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
SRR25158351_k127_744242_3	570268.ANBB01000046_gene1315	9.743e-107	360.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4EFSE@85012|Streptosporangiales	201174|Actinobacteria	S	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
SRR25158351_k127_744242_9	1150864.MILUP08_43709	1.064e-47	184.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4DB50@85008|Micromonosporales	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtC	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_6
SRR25158351_k127_744242_5	909613.UO65_2245	1.54e-88	304.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4DYPU@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158351_k127_744242_4	443218.AS9A_3398	1.114e-99	337.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,233KG@1762|Mycobacteriaceae	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158351_k127_744242_7	358823.DF19_11725	3.84e-57	216.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria	201174|Actinobacteria	G	Inositol monophosphatase	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_744242_10	521011.Mpal_1820	7.43e-40	166.0	COG3503@1|root,arCOG04370@2157|Archaea,2XWYK@28890|Euryarchaeota,2N9R6@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
SRR25158351_k127_744242_0	309801.trd_A0562	0.0	1152.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,27XND@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158351_k127_744242_1	502025.Hoch_5309	2.346e-230	726.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158351_k127_744242_6	469383.Cwoe_3472	2.276e-66	234.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158351_k127_744242_11	1121877.JQKF01000012_gene330	6.221e-35	139.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158351_k127_746732_2	469383.Cwoe_3402	2.492e-27	121.0	2B412@1|root,31WRB@2|Bacteria,2HY97@201174|Actinobacteria,4CQGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_746732_0	1150398.JIBJ01000013_gene2548	8.667e-35	137.0	2EN3K@1|root,33FRP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_746732_3	1380390.JIAT01000009_gene877	6.076e-15	80.0	COG1226@1|root,COG1294@1|root,COG1226@2|Bacteria,COG1294@2|Bacteria,2HPDW@201174|Actinobacteria,4CQRY@84995|Rubrobacteria	84995|Rubrobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158351_k127_746732_1	1242864.D187_000040	2.062e-32	129.0	COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,42R9T@68525|delta/epsilon subdivisions,2WMWQ@28221|Deltaproteobacteria,2YTYH@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
SRR25158351_k127_750276_2	1380390.JIAT01000011_gene2725	1.157e-67	250.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4CPAW@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_750276_7	272134.KB731324_gene5269	0.00013	51.0	COG0589@1|root,COG0589@2|Bacteria,1G6JK@1117|Cyanobacteria,1HC3A@1150|Oscillatoriales	1117|Cyanobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_750276_6	1123065.ATWL01000020_gene3519	7.484e-05	49.0	28ND6@1|root,2ZBG0@2|Bacteria,2H5QC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_750276_1	1382306.JNIM01000001_gene4148	2.392e-76	269.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi	200795|Chloroflexi	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_750276_3	469383.Cwoe_5776	6.99e-29	132.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4CS5W@84995|Rubrobacteria	84995|Rubrobacteria	P	CopC domain	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158351_k127_750276_0	867845.KI911784_gene2483	2.571e-245	767.0	COG2225@1|root,COG2225@2|Bacteria,2G63R@200795|Chloroflexi,374XP@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM malate synthase A	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158351_k127_750276_4	929712.KI912613_gene2219	5.562e-14	78.0	COG2062@1|root,COG2062@2|Bacteria,2HPES@201174|Actinobacteria,4CQT1@84995|Rubrobacteria	84995|Rubrobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158351_k127_750276_5	1120792.JAFV01000001_gene2188	1.582e-11	67.0	COG2207@1|root,COG2207@2|Bacteria,1RJPK@1224|Proteobacteria,2TTNE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	AraC family	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158351_k127_765508_2	42256.RradSPS_0544	1.824e-57	219.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158351_k127_765508_3	1342301.JASD01000008_gene679	1.124e-25	122.0	COG2227@1|root,COG2227@2|Bacteria,1NB77@1224|Proteobacteria,2UARG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158351_k127_765508_1	479434.Sthe_0849	8.122e-70	251.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158351_k127_765508_0	479434.Sthe_0859	1.836e-98	332.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,27XQE@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_76980_4	1449048.JQKU01000019_gene4143	2.726e-92	317.0	COG0604@1|root,COG0604@2|Bacteria,2HWXG@201174|Actinobacteria,235KU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158351_k127_76980_11	1449048.JQKU01000019_gene4143	2.722e-43	171.0	COG0604@1|root,COG0604@2|Bacteria,2HWXG@201174|Actinobacteria,235KU@1762|Mycobacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158351_k127_76980_8	479433.Caci_0871	3.864e-59	213.0	COG2346@1|root,COG3369@1|root,COG3592@1|root,COG2346@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,2I95U@201174|Actinobacteria	201174|Actinobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin,Fer4_19,zf-CDGSH
SRR25158351_k127_76980_1	688245.CtCNB1_1927	1.109e-195	635.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158351_k127_76980_15	1172180.KB911802_gene5174	2.421e-24	113.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158351_k127_76980_13	1157638.KB892191_gene5134	2.077e-28	125.0	COG1917@1|root,COG1917@2|Bacteria,2I4I7@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158351_k127_76980_7	547559.Nmag_1196	1.81e-66	238.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XSXC@28890|Euryarchaeota,23U7D@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158351_k127_76980_6	1121952.ATXT01000011_gene3025	2.759e-82	307.0	COG2909@1|root,COG3710@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria,4FMKW@85023|Microbacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
SRR25158351_k127_76980_9	690850.Desaf_0449	9.436e-58	207.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MEYB@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158351_k127_76980_18	1121875.KB907549_gene1716	1.135e-13	79.0	2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
SRR25158351_k127_76980_17	543632.JOJL01000012_gene6673	1.011e-19	94.0	COG1917@1|root,COG1917@2|Bacteria,2IRRU@201174|Actinobacteria,4DJUR@85008|Micromonosporales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_76980_0	469383.Cwoe_2724	0.0	1195.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria,4CRMG@84995|Rubrobacteria	84995|Rubrobacteria	P	Peroxidase	-	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158351_k127_76980_14	1123401.JHYQ01000007_gene503	3.566e-25	119.0	COG1470@1|root,COG2304@1|root,COG3291@1|root,COG3420@1|root,COG1470@2|Bacteria,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,1RGM6@1224|Proteobacteria,1S5SV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SRR25158351_k127_76980_3	1382356.JQMP01000003_gene1751	3.309e-116	389.0	COG0174@1|root,COG0174@2|Bacteria,2G62E@200795|Chloroflexi,27Z5C@189775|Thermomicrobia	189775|Thermomicrobia	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
SRR25158351_k127_76980_10	469383.Cwoe_4259	3.129e-49	186.0	COG1376@1|root,COG1376@2|Bacteria,2HQX3@201174|Actinobacteria,4CSPQ@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158351_k127_76980_19	927704.SELR_01610	6.963e-10	72.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4H1VN@909932|Negativicutes	909932|Negativicutes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	AMIN,NAGPA
SRR25158351_k127_76980_16	1380356.JNIK01000003_gene1236	2.857e-23	109.0	COG1672@1|root,COG1672@2|Bacteria,2IGAA@201174|Actinobacteria,4ET1R@85013|Frankiales	201174|Actinobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158351_k127_76980_20	1462526.BN990_02900	8.575e-05	52.0	2DK6D@1|root,308Q6@2|Bacteria,1U3TT@1239|Firmicutes,4IDKT@91061|Bacilli,4C6XK@84406|Virgibacillus	91061|Bacilli	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
SRR25158351_k127_76980_21	1218084.BBJK01000030_gene2866	0.0003293	49.0	COG5485@1|root,COG5485@2|Bacteria,1RDG8@1224|Proteobacteria,2VS66@28216|Betaproteobacteria,1K7UQ@119060|Burkholderiaceae	1224|Proteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158351_k127_76980_5	485913.Krac_6795	7.801e-89	302.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi	200795|Chloroflexi	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158351_k127_76980_2	237368.SCABRO_01193	1.4e-145	481.0	COG0674@1|root,COG0674@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158351_k127_771646_26	29540.C481_04146	0.0007783	46.0	COG3548@1|root,arCOG04887@2157|Archaea,2XUMU@28890|Euryarchaeota,23UZ5@183963|Halobacteria	183963|Halobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158351_k127_771646_20	469383.Cwoe_0449	6.547e-16	83.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158351_k127_771646_3	1380390.JIAT01000009_gene2262	1.623e-98	328.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158351_k127_771646_12	394221.Mmar10_2107	3.986e-28	123.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U86R@28211|Alphaproteobacteria,4410J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158351_k127_771646_15	1177179.A11A3_06853	2.178e-24	116.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1XKFY@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the HSP15 family	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRR25158351_k127_771646_18	1089544.KB912942_gene1813	5.499e-19	91.0	COG1018@1|root,COG4097@1|root,COG1018@2|Bacteria,COG4097@2|Bacteria,2GKGS@201174|Actinobacteria	2|Bacteria	C	Oxidoreductase FAD-binding domain	paaE	GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	1.18.1.3	ko:K00529,ko:K02613	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783,R09838	RC00098,RC02690	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A1479	FAD_binding_6,Fer2,NAD_binding_1
SRR25158351_k127_771646_25	1089544.KB912942_gene1813	1.025e-05	51.0	COG1018@1|root,COG4097@1|root,COG1018@2|Bacteria,COG4097@2|Bacteria,2GKGS@201174|Actinobacteria	2|Bacteria	C	Oxidoreductase FAD-binding domain	paaE	GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	1.18.1.3	ko:K00529,ko:K02613	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783,R09838	RC00098,RC02690	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A1479	FAD_binding_6,Fer2,NAD_binding_1
SRR25158351_k127_771646_14	1089544.KB912942_gene1812	9.157e-25	109.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria,4DYZM@85010|Pseudonocardiales	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158351_k127_771646_22	1122939.ATUD01000005_gene2794	1.515e-13	79.0	2C254@1|root,2ZWPJ@2|Bacteria,2INBE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_771646_5	266117.Rxyl_2407	8.268e-84	286.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4CSW4@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158351_k127_771646_6	999141.GME_07211	7.747e-71	251.0	COG1073@1|root,COG1073@2|Bacteria,1N3EW@1224|Proteobacteria,1SIFH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158351_k127_771646_7	1382306.JNIM01000001_gene2779	2.335e-70	253.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_771646_24	4565.Traes_2DL_60E7852F7.2	4.448e-07	58.0	COG0589@1|root,2RZF9@2759|Eukaryota,37V17@33090|Viridiplantae,3GISS@35493|Streptophyta,3M009@4447|Liliopsida,3IHI6@38820|Poales	35493|Streptophyta	T	Universal stress protein family	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158351_k127_771646_0	469383.Cwoe_2846	1.518e-131	433.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CPW0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_771646_8	929712.KI912613_gene2011	3.034e-53	199.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR25158351_k127_771646_13	35754.JNYJ01000009_gene2097	1.39e-25	115.0	COG1418@1|root,COG1418@2|Bacteria,2IAVS@201174|Actinobacteria,4DEHP@85008|Micromonosporales	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158351_k127_771646_2	1313172.YM304_15180	2.169e-103	356.0	COG1178@1|root,COG1178@2|Bacteria,2HFVM@201174|Actinobacteria,4CP3M@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158351_k127_771646_1	1313172.YM304_15190	4.991e-104	347.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158351_k127_771646_4	326427.Cagg_2622	9.585e-89	305.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi,37556@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158351_k127_771646_10	929712.KI912613_gene12	1.072e-30	130.0	COG1321@1|root,COG1321@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158351_k127_771646_27	1123060.JONP01000034_gene1925	0.0008554	47.0	2E3X7@1|root,32YUC@2|Bacteria,1NHDZ@1224|Proteobacteria,2UX0P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_771646_16	1177154.Y5S_03013	4.903e-24	106.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158351_k127_771646_17	1123504.JQKD01000012_gene1321	2.942e-21	106.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2VISH@28216|Betaproteobacteria,4AHEY@80864|Comamonadaceae	28216|Betaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158351_k127_771646_11	1463857.JOFZ01000008_gene590	6.176e-30	125.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria	201174|Actinobacteria	I	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158351_k127_771646_9	469383.Cwoe_3475	1.575e-34	146.0	COG3917@1|root,COG3917@2|Bacteria,2HR29@201174|Actinobacteria,4CSX4@84995|Rubrobacteria	84995|Rubrobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158351_k127_771646_23	649638.Trad_2943	2.085e-11	69.0	2EC48@1|root,33633@2|Bacteria,1WKRM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_771646_19	1122201.AUAZ01000001_gene2236	5.606e-16	87.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,1SC6J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulator of	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
SRR25158351_k127_771646_21	469383.Cwoe_0218	2.083e-14	78.0	2EAM3@1|root,334PR@2|Bacteria,2GUFY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158351_k127_79036_0	1122921.KB898185_gene4095	1.433e-69	245.0	COG1216@1|root,COG1216@2|Bacteria,1TXNZ@1239|Firmicutes,4I6PD@91061|Bacilli,26U2K@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
SRR25158351_k127_79036_2	102125.Xen7305DRAFT_00003900	1.194e-51	193.0	COG1898@1|root,COG1898@2|Bacteria,1GAIH@1117|Cyanobacteria	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158351_k127_79036_1	391735.Veis_3054	3.143e-52	197.0	COG2301@1|root,COG2301@2|Bacteria,1RJQ8@1224|Proteobacteria,2VUSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158351_k127_79036_3	760142.Hipma_1415	1.996e-07	53.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2M6WR@213113|Desulfurellales	28221|Deltaproteobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_824141_0	562970.Btus_2357	1.143e-81	286.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,2782X@186823|Alicyclobacillaceae	91061|Bacilli	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_824141_2	1380390.JIAT01000009_gene2066	3.026e-26	121.0	COG1376@1|root,COG1376@2|Bacteria,2HNXN@201174|Actinobacteria,4CQ6A@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158351_k127_824141_5	1120934.KB894405_gene5349	7.812e-11	74.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4E18R@85010|Pseudonocardiales	201174|Actinobacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR25158351_k127_824141_1	1150864.MILUP08_30098	7.243e-31	126.0	COG2905@1|root,COG2905@2|Bacteria,2HUC9@201174|Actinobacteria,4DE72@85008|Micromonosporales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_824141_4	1206743.BAGM01000011_gene3960	1.169e-12	79.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4FXDK@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_824141_3	469383.Cwoe_5234	2.963e-17	93.0	COG1551@1|root,COG1551@2|Bacteria,2GRPH@201174|Actinobacteria	201174|Actinobacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
SRR25158351_k127_831586_18	370438.PTH_0128	1.525e-43	167.0	COG1216@1|root,COG1216@2|Bacteria,1UJRW@1239|Firmicutes,25F86@186801|Clostridia,262I4@186807|Peptococcaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_831586_3	867845.KI911784_gene799	6.287e-143	467.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_831586_2	350054.Mflv_0956	1.875e-212	691.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,232MQ@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158351_k127_831586_6	469383.Cwoe_5755	9.986e-113	372.0	COG1108@1|root,COG1108@2|Bacteria,2ICEW@201174|Actinobacteria,4CSQQ@84995|Rubrobacteria	84995|Rubrobacteria	P	ABC 3 transport family	-	-	-	ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158351_k127_831586_4	469383.Cwoe_5756	4.743e-141	476.0	COG1108@1|root,COG1414@1|root,COG1108@2|Bacteria,COG1414@2|Bacteria,2HPU0@201174|Actinobacteria,4CSUB@84995|Rubrobacteria	84995|Rubrobacteria	P	ABC 3 transport family	-	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158351_k127_831586_7	2074.JNYD01000036_gene5388	2.966e-98	328.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4DZWA@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM ABC transporter	-	-	3.6.3.35	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00243,M00244,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
SRR25158351_k127_831586_8	469383.Cwoe_5758	1.522e-97	329.0	COG0803@1|root,COG0803@2|Bacteria,2HNG5@201174|Actinobacteria,4CRPQ@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K11707	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158351_k127_831586_11	266117.Rxyl_2085	1.985e-75	265.0	COG0715@1|root,COG0715@2|Bacteria,2HFU1@201174|Actinobacteria,4CQ47@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR25158351_k127_831586_15	1184609.KILIM_017_00270	4.302e-48	185.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4F6UE@85018|Dermatophilaceae	201174|Actinobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
SRR25158351_k127_831586_27	1122138.AQUZ01000020_gene8247	3.832e-10	69.0	2CRBS@1|root,32SNS@2|Bacteria,2IQS0@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_831586_26	1114964.L485_15335	8.102e-11	72.0	COG4106@1|root,COG4106@2|Bacteria,1N1SE@1224|Proteobacteria,2UA3W@28211|Alphaproteobacteria,2K4YR@204457|Sphingomonadales	204457|Sphingomonadales	S	Methyltransferase domain	bioC	-	2.1.1.197,6.3.3.3	ko:K01935,ko:K02169	ko00780,ko01100,map00780,map01100	M00123,M00572,M00573,M00577	R03182,R09543	RC00003,RC00460,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158351_k127_831586_16	118161.KB235922_gene5111	5.419e-48	181.0	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158351_k127_831586_24	118161.KB235922_gene396	2.078e-22	109.0	COG5361@1|root,COG5361@2|Bacteria,1G4FQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158351_k127_831586_13	469383.Cwoe_5370	5.935e-61	221.0	COG0842@1|root,COG0842@2|Bacteria,2ICWC@201174|Actinobacteria,4CQA1@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_831586_10	1380390.JIAT01000010_gene4556	1.528e-78	272.0	COG1131@1|root,COG1131@2|Bacteria,2IBZE@201174|Actinobacteria,4CPJZ@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_831586_23	1111479.AXAR01000001_gene92	1.172e-22	104.0	2AJ2R@1|root,319M2@2|Bacteria,1V6IJ@1239|Firmicutes,4HIZD@91061|Bacilli,278J7@186823|Alicyclobacillaceae	91061|Bacilli	S	Conserved hypothetical protein (Lin0512_fam)	-	-	-	-	-	-	-	-	-	-	-	-	Lin0512_fam
SRR25158351_k127_831586_22	1121413.JMKT01000009_gene2170	1.462e-27	118.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158351_k127_831586_17	222534.KB893751_gene4131	1.154e-43	164.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158351_k127_831586_25	479433.Caci_6597	5.627e-21	96.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158351_k127_831586_21	1380393.JHVP01000004_gene404	3.306e-39	151.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria,4EVJ5@85013|Frankiales	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_831586_28	330214.NIDE3177	1.185e-08	64.0	COG0484@1|root,COG1948@1|root,COG0484@2|Bacteria,COG1948@2|Bacteria	2|Bacteria	L	resolution of meiotic recombination intermediates	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,ERCC4,Lsr2
SRR25158351_k127_831586_1	1121382.JQKG01000005_gene3283	1.482e-240	755.0	COG0166@1|root,COG0166@2|Bacteria,1WIGN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158351_k127_831586_5	469383.Cwoe_0108	1.581e-114	377.0	COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria,4CSJ2@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158351_k127_831586_20	1283299.AUKG01000003_gene235	1.358e-39	160.0	COG3336@1|root,COG3336@2|Bacteria,2HPY7@201174|Actinobacteria,4CRDE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158351_k127_831586_12	926550.CLDAP_17990	5.394e-71	252.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158351_k127_831586_14	926550.CLDAP_18000	3.857e-51	192.0	COG1121@1|root,COG1121@2|Bacteria	2|Bacteria	P	zinc-transporting ATPase activity	-	-	-	ko:K09820,ko:K11607,ko:K11710	ko02010,map02010	M00243,M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
SRR25158351_k127_831586_19	1313172.YM304_05710	6.339e-41	168.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158351_k127_831586_0	1089552.KI911559_gene890	0.0	1014.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
SRR25158351_k127_831586_9	1205680.CAKO01000002_gene2361	2.402e-91	314.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,2JP84@204441|Rhodospirillales	204441|Rhodospirillales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158351_k127_838607_2	1464048.JNZS01000007_gene4510	2.282e-97	323.0	2E8HM@1|root,332VQ@2|Bacteria,2IGA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRR25158351_k127_838607_4	709986.Deima_2749	3.37e-49	188.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	lacI	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158351_k127_838607_3	1283299.AUKG01000001_gene3186	1.889e-52	201.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CQ00@84995|Rubrobacteria	84995|Rubrobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158351_k127_838607_5	420247.Msm_1334	2.039e-20	102.0	COG0679@1|root,arCOG04756@2157|Archaea,2XU4B@28890|Euryarchaeota,23P1C@183925|Methanobacteria	183925|Methanobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158351_k127_838607_0	1382306.JNIM01000001_gene2675	3.737e-215	684.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_15
SRR25158351_k127_838607_1	1380390.JIAT01000003_gene5448	2.795e-114	371.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4CPYH@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158351_k127_838607_6	546271.Selsp_0706	1.901e-18	86.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes	909932|Negativicutes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_861723_3	502025.Hoch_3588	3.497e-65	233.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,43190@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Fructosamine kinase	yniA	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158351_k127_861723_5	1380390.JIAT01000009_gene1008	1.55e-53	193.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CQF3@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158351_k127_861723_9	931627.MycrhDRAFT_6594	5.424e-09	70.0	2EMTZ@1|root,30U9E@2|Bacteria,2GRBP@201174|Actinobacteria,23E66@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_861723_4	66874.JOFS01000040_gene6773	3.471e-63	246.0	COG3307@1|root,COG3307@2|Bacteria,2IBT0@201174|Actinobacteria	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158351_k127_861723_2	929712.KI912613_gene2163	4.36e-78	286.0	COG0596@1|root,COG0596@2|Bacteria,2HQ97@201174|Actinobacteria,4CRT5@84995|Rubrobacteria	84995|Rubrobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158351_k127_861723_0	497964.CfE428DRAFT_5336	1.685e-103	347.0	COG2230@1|root,COG2230@2|Bacteria,46TH2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158351_k127_861723_1	756272.Plabr_2027	2.938e-79	272.0	COG3752@1|root,COG3752@2|Bacteria,2IZ0I@203682|Planctomycetes	203682|Planctomycetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
SRR25158351_k127_861723_7	345341.KUTG_07818	1.533e-17	94.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4E3B2@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphoesterase	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158351_k127_861723_10	1122939.ATUD01000022_gene3680	4.046e-08	63.0	COG4395@1|root,COG4395@2|Bacteria,2IDZ3@201174|Actinobacteria,4CPKH@84995|Rubrobacteria	84995|Rubrobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRR25158351_k127_861723_8	1280689.AUJC01000003_gene1357	7.001e-15	84.0	COG4395@1|root,COG4395@2|Bacteria,1V9GZ@1239|Firmicutes,24HB5@186801|Clostridia,36J5E@31979|Clostridiaceae	186801|Clostridia	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRR25158351_k127_861723_6	469383.Cwoe_0729	8.218e-37	156.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Muraidase,PG_binding_1
SRR25158351_k127_875103_6	635013.TherJR_1258	5.216e-15	85.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158351_k127_875103_0	479434.Sthe_0926	1.225e-77	279.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27XTB@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158351_k127_875103_5	1121472.AQWN01000004_gene697	5.747e-26	118.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,25ZZ6@186807|Peptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
SRR25158351_k127_875103_3	1283299.AUKG01000002_gene4575	7.507e-35	147.0	COG1657@1|root,COG1657@2|Bacteria,2HQIZ@201174|Actinobacteria,4CS4F@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_875103_4	228410.NE2041	1.728e-32	142.0	2CCJR@1|root,2ZCU4@2|Bacteria,1RC7F@1224|Proteobacteria,2W4MN@28216|Betaproteobacteria,3720D@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_875103_2	1380356.JNIK01000013_gene4125	1.483e-37	156.0	2DE9Z@1|root,32U2Z@2|Bacteria,2ID6V@201174|Actinobacteria,4EW0B@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_875103_1	469383.Cwoe_1802	1.015e-53	203.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158351_k127_8910_12	469383.Cwoe_3103	3.231e-25	113.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158351_k127_8910_1	338966.Ppro_3060	1.521e-131	427.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,43UE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
SRR25158351_k127_8910_3	1235794.C811_00793	1.229e-111	387.0	COG0751@1|root,COG0751@2|Bacteria,2HFU4@201174|Actinobacteria,4CUAK@84998|Coriobacteriia	84998|Coriobacteriia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRR25158351_k127_8910_14	326424.FRAAL6646	4.905e-11	70.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4ERP1@85013|Frankiales	201174|Actinobacteria	S	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_8910_10	469383.Cwoe_4241	6.641e-60	219.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4CRVY@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_8910_15	1386089.N865_02795	0.0001618	50.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4FFEC@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_8910_11	3988.XP_002524661.1	1.795e-54	195.0	COG2138@1|root,2RXIW@2759|Eukaryota,37TYY@33090|Viridiplantae,3GHWI@35493|Streptophyta,4JNWD@91835|fabids	35493|Streptophyta	S	Sirohydrochlorin	-	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
SRR25158351_k127_8910_7	266117.Rxyl_1503	2.16e-90	316.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158351_k127_8910_9	1380390.JIAT01000007_gene5188	5.149e-76	277.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CPNK@84995|Rubrobacteria	84995|Rubrobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158351_k127_8910_13	216594.MMAR_4436	2.3e-12	74.0	2B2M4@1|root,31V6I@2|Bacteria,2GV2T@201174|Actinobacteria,23DZT@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_8910_8	644966.Tmar_1461	3.617e-78	279.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,24J4X@186801|Clostridia	186801|Clostridia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_8910_2	1214101.BN159_6130	8.323e-114	376.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158351_k127_8910_5	1206101.AZXC01000027_gene5563	1.168e-106	356.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158351_k127_8910_6	469383.Cwoe_4494	2.692e-93	326.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158351_k127_8910_4	1173028.ANKO01000166_gene4297	1.703e-111	374.0	COG1117@1|root,COG1117@2|Bacteria,1G0P6@1117|Cyanobacteria,1H8Z3@1150|Oscillatoriales	1117|Cyanobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158351_k127_8910_0	469383.Cwoe_2866	6.565e-168	545.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158351_k127_902672_11	164757.Mjls_1855	2.654e-11	68.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,233F0@1762|Mycobacteriaceae	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158351_k127_902672_12	1193181.BN10_360008	4.14e-09	64.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria,4FHSC@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158351_k127_902672_3	526225.Gobs_2308	1.627e-134	439.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Peptidase_S9
SRR25158351_k127_902672_8	469383.Cwoe_4528	1.582e-59	219.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CQ0V@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158351_k127_902672_4	867903.ThesuDRAFT_00613	4.108e-124	411.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WCWM@538999|Clostridiales incertae sedis	186801|Clostridia	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158351_k127_902672_2	288705.RSal33209_2271	3.167e-137	445.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,1W7Q3@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158351_k127_902672_5	1121468.AUBR01000012_gene2576	2.175e-87	299.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,42EVZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158351_k127_902672_6	867903.ThesuDRAFT_02338	5.078e-85	292.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WCG1@538999|Clostridiales incertae sedis	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158351_k127_902672_1	469383.Cwoe_4536	2.292e-196	642.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158351_k127_902672_10	1380390.JIAT01000010_gene4799	1.656e-36	149.0	COG1376@1|root,COG1376@2|Bacteria,2IHC7@201174|Actinobacteria,4CT4W@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158351_k127_902672_7	929712.KI912613_gene3008	2.048e-73	266.0	COG0741@1|root,COG1876@1|root,COG0741@2|Bacteria,COG1876@2|Bacteria,2I4JK@201174|Actinobacteria,4CQYM@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	SLT,VanY
SRR25158351_k127_902672_13	479433.Caci_1944	0.00014	47.0	2DG6U@1|root,2ZURF@2|Bacteria,2HCGM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_902672_0	264732.Moth_1759	3.411e-206	661.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,42EQA@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158351_k127_906915_1	1206744.BAGL01000055_gene1559	7.597e-93	316.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,4FU1E@85025|Nocardiaceae	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_906915_5	1255043.TVNIR_3628	3.474e-41	159.0	COG1309@1|root,COG1309@2|Bacteria,1RF0W@1224|Proteobacteria,1S8MA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158351_k127_906915_2	530564.Psta_4683	2.191e-88	303.0	COG0707@1|root,COG0707@2|Bacteria,2IX27@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
SRR25158351_k127_906915_7	1313172.YM304_40110	1.455e-17	93.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158351_k127_906915_0	47839.CCAU010000005_gene481	1.454e-112	391.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,2366A@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158351_k127_906915_4	557599.MKAN_01345	3.77e-43	173.0	COG0062@1|root,COG0062@2|Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158351_k127_906915_3	285535.JOEY01000034_gene9894	6.703e-73	266.0	COG0596@1|root,COG0654@1|root,COG0596@2|Bacteria,COG0654@2|Bacteria,2GJDM@201174|Actinobacteria	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158351_k127_906915_6	222534.KB893719_gene1064	1.743e-30	133.0	COG2141@1|root,COG2141@2|Bacteria,2IBDS@201174|Actinobacteria	201174|Actinobacteria	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_907307_0	1123393.KB891326_gene73	3.962e-112	374.0	COG0462@1|root,COG0462@2|Bacteria,1QHJ7@1224|Proteobacteria,2VJW9@28216|Betaproteobacteria,1KSMN@119069|Hydrogenophilales	119069|Hydrogenophilales	EF	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158351_k127_907307_1	1123393.KB891326_gene72	1.106e-98	333.0	COG2187@1|root,COG2187@2|Bacteria,1R98V@1224|Proteobacteria,2VM22@28216|Betaproteobacteria,1KSS9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_907307_6	1121920.AUAU01000014_gene2790	1.008e-12	75.0	2EK70@1|root,33DXD@2|Bacteria,3Y5QD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_907307_3	1449069.JMLO01000010_gene415	5.071e-29	119.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria,4G2Q6@85025|Nocardiaceae	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158351_k127_907307_2	1150864.MILUP08_45835	9.026e-34	137.0	COG3476@1|root,COG3476@2|Bacteria,2IQA5@201174|Actinobacteria,4DEFB@85008|Micromonosporales	201174|Actinobacteria	T	PFAM TspO MBR family protein	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRR25158351_k127_907307_5	285535.JOEY01000014_gene4531	1.525e-14	82.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158351_k127_907307_4	656024.FsymDg_3050	1.269e-28	121.0	COG1233@1|root,COG1233@2|Bacteria,2GP0A@201174|Actinobacteria	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158351_k127_912062_4	379066.GAU_0527	2.679e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_912062_6	1122602.ATXP01000021_gene139	0.0002932	45.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158351_k127_912062_5	441620.Mpop_1852	1.249e-14	80.0	2F3GP@1|root,33WAD@2|Bacteria,1NWJ1@1224|Proteobacteria,2USQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_912062_1	309801.trd_0272	5.361e-61	220.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_912062_2	292459.STH607	8.105e-49	191.0	COG0577@1|root,COG0577@2|Bacteria,1TUYK@1239|Firmicutes,24DGM@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_912062_3	1077972.ARGLB_113_00300	1.024e-31	134.0	COG4319@1|root,COG4319@2|Bacteria,2IHRK@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158351_k127_912062_0	1122622.ATWJ01000014_gene408	3.093e-62	235.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158351_k127_919234_1	500153.JOEK01000003_gene1048	2.37e-39	150.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_919234_2	929712.KI912613_gene960	1.585e-34	137.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CQN4@84995|Rubrobacteria	84995|Rubrobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158351_k127_919234_0	1380390.JIAT01000009_gene2039	1.735e-41	156.0	COG2411@1|root,COG2411@2|Bacteria,2HNQQ@201174|Actinobacteria,4CPX9@84995|Rubrobacteria	84995|Rubrobacteria	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158351_k127_919234_3	405948.SACE_7378	1.385e-22	103.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4E30H@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158351_k127_936224_1	744980.TRICHSKD4_1098	2.147e-33	151.0	COG0175@1|root,COG0175@2|Bacteria,1PA2H@1224|Proteobacteria,2U5GP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
SRR25158351_k127_936224_2	680198.SCAB_33391	5.551e-15	88.0	COG0175@1|root,COG0175@2|Bacteria,2GK5Y@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_936224_0	1509405.GV67_04040	4.913e-37	152.0	COG0863@1|root,COG0863@2|Bacteria,1R7RR@1224|Proteobacteria,2TS8Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158351_k127_941602_2	42256.RradSPS_2724	8.31e-79	277.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158351_k127_941602_8	1120936.KB907219_gene3139	1.912e-21	97.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4EK27@85012|Streptosporangiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	sufE	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158351_k127_941602_1	935839.JAGJ01000003_gene1361	9.835e-99	330.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4F410@85017|Promicromonosporaceae	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158351_k127_941602_0	321327.CYA_0391	1.679e-144	468.0	COG0520@1|root,COG0520@2|Bacteria,1G15D@1117|Cyanobacteria,1GZJ6@1129|Synechococcus	1117|Cyanobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158351_k127_941602_3	1122921.KB898191_gene2019	1.547e-39	151.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,26WQ4@186822|Paenibacillaceae	91061|Bacilli	C	Nitrogen fixation protein NifU	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158351_k127_941602_4	926554.KI912617_gene4826	1.313e-30	123.0	COG2151@1|root,COG2151@2|Bacteria,1WK4T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2151 metal-sulfur cluster biosynthetic protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158351_k127_941602_7	1396141.BATP01000058_gene1948	2.233e-23	104.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia,2IUGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158351_k127_941602_6	195103.CPF_0281	5.013e-24	113.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,36ESU@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158351_k127_941602_5	1229780.BN381_210085	1.904e-28	131.0	COG0739@1|root,COG0739@2|Bacteria,2HFQA@201174|Actinobacteria,3UWZQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158351_k127_950335_8	345341.KUTG_04413	9.158e-51	196.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
SRR25158351_k127_950335_3	402881.Plav_2147	8.111e-79	275.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TUT7@28211|Alphaproteobacteria,1JNXV@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	MA20_36480	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
SRR25158351_k127_950335_4	713586.KB900536_gene2300	6.676e-59	216.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria,1X0XH@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158351_k127_950335_2	1122138.AQUZ01000019_gene8179	3.987e-102	362.0	COG2890@1|root,COG2890@2|Bacteria,2I3R2@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158351_k127_950335_0	1194165.CAJF01000011_gene1034	0.0	1172.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158351_k127_950335_9	94624.Bpet1808	1.611e-43	166.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2VHU3@28216|Betaproteobacteria,3T31V@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158351_k127_950335_6	1051632.TPY_1473	2.385e-55	203.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR25158351_k127_950335_5	1380390.JIAT01000016_gene5607	5.452e-56	210.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CPX0@84995|Rubrobacteria	84995|Rubrobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158351_k127_950335_1	266117.Rxyl_2090	3.7e-152	491.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CP72@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_950335_11	1122194.AUHU01000002_gene2568	7.557e-40	158.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,466TM@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158351_k127_950335_13	867903.ThesuDRAFT_00030	7.915e-28	126.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,3WDR4@538999|Clostridiales incertae sedis	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158351_k127_950335_12	267608.RSp0980	3.684e-28	117.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1K518@119060|Burkholderiaceae	28216|Betaproteobacteria	K	regulator	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158351_k127_950335_10	479433.Caci_7589	2.896e-40	158.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_950335_7	338963.Pcar_1504	2.51e-51	186.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,43UX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	FG	Protein similar to CwfJ C-terminus 1	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
SRR25158351_k127_950335_14	1298863.AUEP01000011_gene532	4.42e-10	61.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4DPGJ@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_981224_10	1455608.JDTH01000013_gene26	1.27e-11	74.0	COG0463@1|root,arCOG01385@2157|Archaea,2Y7PB@28890|Euryarchaeota,23UIK@183963|Halobacteria	183963|Halobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158351_k127_981224_2	886293.Sinac_4405	1.705e-54	204.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRR25158351_k127_981224_6	562970.Btus_0876	8.97e-22	105.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,4I47R@91061|Bacilli,279PC@186823|Alicyclobacillaceae	91061|Bacilli	P	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158351_k127_981224_4	1123320.KB889607_gene9517	2.857e-41	171.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158351_k127_981224_0	192952.MM_2103	1.911e-63	228.0	COG0500@1|root,arCOG07825@2157|Archaea	2157|Archaea	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158351_k127_981224_7	477974.Daud_1081	9.615e-19	101.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,261SN@186807|Peptococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158351_k127_981224_5	420662.Mpe_A0734	3.289e-30	136.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,1KMHG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRR25158351_k127_981224_3	383372.Rcas_1348	3.988e-53	198.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158351_k127_981224_1	526225.Gobs_0348	2.025e-62	234.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158351_k127_981224_8	1144275.COCOR_05695	5.711e-14	84.0	COG5650@1|root,COG5650@2|Bacteria	2|Bacteria	M	phosphatidylinositol metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158351_k127_981224_9	1408452.JAGZ01000001_gene4034	7.437e-14	84.0	2F13Q@1|root,33U55@2|Bacteria,2I955@201174|Actinobacteria,232E9@1762|Mycobacteriaceae	201174|Actinobacteria	S	capsule organization	aftC	GO:0008150,GO:0040007	2.4.2.47	ko:K16647	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
SRR25158351_k127_982925_25	630626.EBL_c34860	2.238e-07	53.0	COG0074@1|root,COG0074@2|Bacteria,1MX67@1224|Proteobacteria,1RQEG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF1116)	ylbE	-	-	-	-	-	-	-	-	-	-	-	DUF1116
SRR25158351_k127_982925_27	938709.AUSH02000051_gene230	9.536e-07	60.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_982925_13	1121887.AUDK01000001_gene764	1.718e-40	154.0	COG0599@1|root,COG0599@2|Bacteria,4PCXF@976|Bacteroidetes,1IDF1@117743|Flavobacteriia,2NY6K@237|Flavobacterium	976|Bacteroidetes	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158351_k127_982925_18	1298863.AUEP01000013_gene4082	6.615e-17	83.0	2C6FT@1|root,334HA@2|Bacteria,2HCTI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_982925_7	266117.Rxyl_0510	2.168e-69	243.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158351_k127_982925_16	1293054.HSACCH_01736	9.482e-23	102.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WATQ@53433|Halanaerobiales	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158351_k127_982925_5	1283299.AUKG01000003_gene500	7.017e-88	313.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158351_k127_982925_24	1123052.AUDF01000002_gene672	1.998e-07	56.0	2BRXQ@1|root,32KXZ@2|Bacteria,2IPG4@201174|Actinobacteria	201174|Actinobacteria	S	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158351_k127_982925_2	1173024.KI912151_gene2146	4.547e-163	528.0	COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae	1117|Cyanobacteria	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
SRR25158351_k127_982925_3	448385.sce9042	3.623e-121	407.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,1RDAY@1224|Proteobacteria,43CWS@68525|delta/epsilon subdivisions,2X84R@28221|Deltaproteobacteria,2YX1U@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158351_k127_982925_15	292459.STH1996	3.824e-25	113.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia	186801|Clostridia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158351_k127_982925_10	1156919.QWC_14447	6.143e-53	199.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2VHKN@28216|Betaproteobacteria,3T2W2@506|Alcaligenaceae	28216|Betaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158351_k127_982925_17	469383.Cwoe_3360	3.856e-17	95.0	COG2132@1|root,COG3386@1|root,COG2132@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	1.7.2.1	ko:K00368,ko:K07004	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	ASH,Copper-bind,Cu-oxidase_2,Cu-oxidase_3,DUF3739,Haemagg_act,MRJP,SGL
SRR25158351_k127_982925_32	1192034.CAP_1912	0.0001359	54.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_982925_19	1380390.JIAT01000009_gene338	1.375e-12	79.0	COG2931@1|root,COG2931@2|Bacteria,2IPR5@201174|Actinobacteria,4CS6K@84995|Rubrobacteria	84995|Rubrobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158351_k127_982925_0	1313172.YM304_34590	1.139e-268	837.0	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,2GN09@201174|Actinobacteria,4CMR1@84992|Acidimicrobiia	201174|Actinobacteria	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rieske
SRR25158351_k127_982925_31	1209984.BN978_02143	2.982e-05	53.0	2BFCX@1|root,32969@2|Bacteria,2HSWS@201174|Actinobacteria,23EBQ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_982925_1	1229203.KI301992_gene71	2.078e-178	584.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_982925_14	1229780.BN381_90032	5.496e-29	121.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
SRR25158351_k127_982925_30	1313172.YM304_05820	1.281e-05	53.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4CNF3@84992|Acidimicrobiia	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158351_k127_982925_8	1313172.YM304_05820	5.707e-61	218.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4CNF3@84992|Acidimicrobiia	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158351_k127_982925_28	1123284.KB899060_gene814	5.329e-06	52.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli	91061|Bacilli	C	nadph quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158351_k127_982925_23	208439.AJAP_08260	9.094e-09	61.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4E0YD@85010|Pseudonocardiales	201174|Actinobacteria	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158351_k127_982925_9	1123247.AUIJ01000041_gene300	4.234e-60	218.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158351_k127_982925_21	469383.Cwoe_1170	2.748e-10	71.0	2B09U@1|root,31SKS@2|Bacteria,2HUBE@201174|Actinobacteria,4CU0W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_982925_11	1172188.KB911822_gene698	1.298e-49	186.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4FGCG@85021|Intrasporangiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158351_k127_982925_4	469383.Cwoe_1972	9.596e-95	320.0	28HGI@1|root,2Z9T0@2|Bacteria,2ICRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_982925_6	882086.SacxiDRAFT_4007	2.749e-79	274.0	COG4976@1|root,COG4976@2|Bacteria,2IGUS@201174|Actinobacteria,4E3AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158351_k127_982925_20	266940.Krad_1063	7.569e-12	78.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
SRR25158351_k127_982925_12	1120958.AULD01000005_gene1667	2.708e-45	168.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4FPAS@85023|Microbacteriaceae	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158351_k127_982925_29	365528.KB891216_gene2576	1.235e-05	57.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC,CopD
SRR25158351_k127_982925_22	330084.JNYZ01000042_gene5043	5.486e-09	64.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4DXVV@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158351_k127_994601_8	1440774.Y900_005115	4.457e-21	93.0	COG5031@1|root,COG5031@2|Bacteria,2IF2J@201174|Actinobacteria,236U3@1762|Mycobacteriaceae	201174|Actinobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_994601_9	1205680.CAKO01000040_gene1125	2.965e-13	77.0	COG5031@1|root,COG5031@2|Bacteria,1REM1@1224|Proteobacteria,2U762@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_994601_3	298655.KI912266_gene6468	2.476e-75	280.0	COG0477@1|root,COG0477@2|Bacteria,2IDYF@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_994601_0	1043205.AFYF01000051_gene3051	4.934e-171	555.0	COG0471@1|root,COG0471@2|Bacteria,2HXIC@201174|Actinobacteria,4FH0P@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
SRR25158351_k127_994601_7	1463856.JOHY01000003_gene5139	5.243e-27	118.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158351_k127_994601_5	369723.Strop_1405	7.655e-49	185.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4D94Y@85008|Micromonosporales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158351_k127_994601_1	469383.Cwoe_5880	1.389e-141	466.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CPJJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158351_k127_994601_4	946483.Cenrod_1750	8.804e-63	226.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,4ABY8@80864|Comamonadaceae	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158351_k127_994601_2	929712.KI912613_gene866	3.424e-94	325.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158351_k127_994601_6	644282.Deba_0329	8.745e-34	138.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,42QT2@68525|delta/epsilon subdivisions,2WN1F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
SRR25158351_k127_994601_11	469383.Cwoe_5876	3.529e-05	49.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CSM2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
## 2222 queries scanned
## Total time (seconds): 5.458174228668213
## Rate: 407.10 q/s