## Thu Feb 19 02:21:08 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158351_bin.37.fa -m mmseqs --output SRR25158351_bin.37 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158351_bin.37 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158351_k127_1004253_0	1120950.KB892768_gene5214	1.079e-172	557.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4DPEJ@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158351_k127_1005555_0	1237500.ANBA01000009_gene1522	3.383e-73	254.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4EGUX@85012|Streptosporangiales	201174|Actinobacteria	P	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	copD	GO:0008150,GO:0040007	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158351_k127_1005555_1	1996.JOFO01000092_gene1079	1.058e-66	235.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4EGPE@85012|Streptosporangiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	mtnU	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158351_k127_1005555_2	469371.Tbis_3442	8.972e-47	173.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4E3MQ@85010|Pseudonocardiales	201174|Actinobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158351_k127_1005555_3	526225.Gobs_0619	6.538e-16	79.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,4ET0G@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158351_k127_1029067_1	1123322.KB904702_gene170	1.186e-32	127.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158351_k127_1029067_0	1035308.AQYY01000002_gene891	6.963e-93	312.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,260AI@186807|Peptococcaceae	186801|Clostridia	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
SRR25158351_k127_1029067_2	1122622.ATWJ01000008_gene2700	2.824e-30	123.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4FF6S@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158351_k127_1035339_0	1504319.GM45_3440	6.147e-144	461.0	COG0160@1|root,COG0160@2|Bacteria,2I2F3@201174|Actinobacteria,3UWC7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
SRR25158351_k127_1035339_1	596328.HMPREF0578_1486	2.07e-60	214.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4D4GW@85005|Actinomycetales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158351_k127_1039563_1	1120950.KB892739_gene3991	6.478e-131	429.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4DNND@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158351_k127_1039563_2	269800.Tfu_0845	2.22e-51	186.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4EIYX@85012|Streptosporangiales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158351_k127_1039563_0	1504319.GM45_5945	2.039e-152	487.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,3UWEM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158351_k127_1045981_1	158189.SpiBuddy_0974	1.605e-30	124.0	COG5646@1|root,COG5646@2|Bacteria,2JAS4@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158351_k127_1045981_0	1347368.HG964406_gene6397	1.36e-136	444.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZDI4@1386|Bacillus	91061|Bacilli	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158351_k127_1058517_1	285535.JOEY01000051_gene1433	1.911e-23	102.0	COG0526@1|root,COG0526@2|Bacteria,2IKMI@201174|Actinobacteria	201174|Actinobacteria	CO	Thioredoxin	thiX	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
SRR25158351_k127_1058517_0	67352.JODS01000070_gene2258	1.255e-39	151.0	2AN8T@1|root,327DN@2|Bacteria,2I81P@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158351_k127_1058517_2	494419.ALPM01000077_gene1638	1.843e-20	93.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,1W8XT@1268|Micrococcaceae	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158351_k127_1062972_2	1906.SFRA_02095	3.27e-19	88.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_1062972_0	1298863.AUEP01000005_gene2555	2.847e-58	210.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4DQEM@85009|Propionibacteriales	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158351_k127_1062972_1	1193181.BN10_680075	1.884e-37	143.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4FHAI@85021|Intrasporangiaceae	201174|Actinobacteria	FG	Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158351_k127_1064267_3	1449976.KALB_3162	1.889e-39	149.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	soxA	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
SRR25158351_k127_1064267_5	680198.SCAB_6921	7.07e-26	114.0	COG4583@1|root,COG4583@2|Bacteria,2HJE7@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase, gamma subunit	soxG	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
SRR25158351_k127_1064267_2	1120950.KB892747_gene3727	8.189e-135	434.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4DNC5@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158351_k127_1064267_0	749927.AMED_7560	2.081e-268	834.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4E0AY@85010|Pseudonocardiales	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158351_k127_1064267_4	1295642.H839_16913	7.885e-30	124.0	COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HH6R@91061|Bacilli	91061|Bacilli	S	general stress protein	ywrO	-	-	ko:K11748	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
SRR25158351_k127_1064267_1	253839.SSNG_02866	6.472e-258	814.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158351_k127_1066261_2	1120949.KB903324_gene3343	1.06e-45	175.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4DDYQ@85008|Micromonosporales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	frk	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1066261_1	446468.Ndas_1471	1.104e-48	179.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4EIS3@85012|Streptosporangiales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158351_k127_1066261_0	1348663.KCH_15680	2.043e-53	196.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,2M102@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158351_k127_1066261_4	408672.NBCG_02774	2.004e-32	132.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DR1A@85009|Propionibacteriales	201174|Actinobacteria	T	zinc-ribbon domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158351_k127_1066261_3	1068978.AMETH_2999	1.897e-42	159.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4E4H7@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158351_k127_1066261_5	1210046.B277_07336	3.007e-14	74.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4FEXI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158351_k127_1073667_0	1380346.JNIH01000062_gene2509	2.598e-118	387.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158351_k127_1073667_2	1188240.MYEA_4550	3.618e-08	58.0	COG3077@1|root,COG3077@2|Bacteria,3WU82@544448|Tenericutes	544448|Tenericutes	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
SRR25158351_k127_1073667_1	1193181.BN10_1300016	2.626e-20	92.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1074210_0	1120950.KB892801_gene1776	2.445e-84	286.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4DPX5@85009|Propionibacteriales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158351_k127_1074210_1	471852.Tcur_4438	6.428e-84	291.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4EFW8@85012|Streptosporangiales	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158351_k127_1080431_7	1223542.GM1_003_02880	1.143e-15	81.0	COG0746@1|root,COG0746@2|Bacteria,2GJVE@201174|Actinobacteria,4GE87@85026|Gordoniaceae	201174|Actinobacteria	H	MobA-like NTP transferase domain	mobA	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158351_k127_1080431_5	479432.Sros_1325	7.785e-68	240.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4EGK7@85012|Streptosporangiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158351_k127_1080431_2	1121019.AUMN01000020_gene1648	1.556e-99	332.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,1W96S@1268|Micrococcaceae	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158351_k127_1080431_3	1121385.AQXW01000004_gene1607	3.402e-75	257.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,1ZVUT@145357|Dermacoccaceae	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158351_k127_1080431_1	479435.Kfla_5331	4.883e-153	495.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DNKT@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
SRR25158351_k127_1080431_4	246200.SPO1598	2.226e-68	242.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2TV0U@28211|Alphaproteobacteria,4NCAF@97050|Ruegeria	28211|Alphaproteobacteria	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
SRR25158351_k127_1080431_6	1120950.KB892709_gene4158	1.315e-37	145.0	COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4DS96@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb2	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_1080431_0	1504319.GM45_5705	1.825e-300	928.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,3UWE5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158351_k127_1080431_8	312153.Pnuc_0815	9.192e-09	57.0	COG0824@1|root,COG0824@2|Bacteria,1MZTU@1224|Proteobacteria,2VSY8@28216|Betaproteobacteria,1KFWN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Thioesterase-like superfamily	fcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158351_k127_1081445_0	1068980.ARVW01000001_gene4128	1.724e-175	554.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4DYQ2@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158351_k127_1081445_1	446470.Snas_5501	1.035e-25	106.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4EXVP@85014|Glycomycetales	201174|Actinobacteria	E	Tetrahydrodipicolinate N-succinyltransferase middle	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
SRR25158351_k127_1088433_3	29306.JOBE01000071_gene4872	0.0002916	46.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria	201174|Actinobacteria	NOU	Peptidase A24A, prepilin type IV	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
SRR25158351_k127_1088433_0	1907.SGLAU_06025	1.506e-171	546.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158351_k127_1088433_1	269800.Tfu_1091	2.121e-40	155.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,4EJ4W@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158351_k127_1088433_2	1223523.H340_09595	1.055e-23	104.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158351_k127_1092332_0	1463917.JODC01000002_gene866	2.373e-150	485.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158351_k127_1097290_1	1504319.GM45_0895	4.263e-138	443.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,3UW8Y@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Class-II DAHP synthetase family	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.5.1.54	ko:K01626,ko:K16019	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01051,map01100,map01110,map01130,map01230,map02024	M00022	R01826,R06591	RC00435,RC01556	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2178c	DAHP_synth_2
SRR25158351_k127_1097290_0	686340.Metal_1094	2.091e-182	578.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1SX3B@1236|Gammaproteobacteria,1XDZ9@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158351_k127_1097290_2	1385519.N801_09350	1.013e-40	152.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FEIG@85021|Intrasporangiaceae	201174|Actinobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158351_k127_1099610_2	1828.JOKB01000061_gene1831	4.815e-57	201.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4FTZ4@85025|Nocardiaceae	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
SRR25158351_k127_1099610_0	105422.BBPM01000024_gene3462	1.459e-145	479.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,2NGDD@228398|Streptacidiphilus	201174|Actinobacteria	L	RecF/RecN/SMC N terminal domain	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158351_k127_1099610_1	58123.JOFJ01000006_gene93	3.719e-57	203.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4EH46@85012|Streptosporangiales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158351_k127_1106418_0	1123320.KB889585_gene1781	1.628e-178	564.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158351_k127_1106418_1	1449346.JQMO01000003_gene3777	2.817e-08	55.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,2M2GN@2063|Kitasatospora	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158351_k127_1109347_0	593907.Celgi_0566	8.361e-65	225.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria	201174|Actinobacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158351_k127_1109347_1	1223523.H340_17672	6.76e-62	218.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria	201174|Actinobacteria	J	N-acetyltransferase	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158351_k127_1111366_1	1463861.JNXE01000005_gene2437	1.224e-113	373.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria	201174|Actinobacteria	F	phosphorylase	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158351_k127_1111366_3	1122182.KB903813_gene2555	5.066e-46	168.0	COG0662@1|root,COG0662@2|Bacteria,2IMHT@201174|Actinobacteria,4DE67@85008|Micromonosporales	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,EutQ
SRR25158351_k127_1111366_0	68194.JNXR01000007_gene4178	2.174e-156	500.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158351_k127_1111366_2	1081644.IMCC13023_03870	2.974e-82	277.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4FM94@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1117794_4	1463900.JOIX01000044_gene6739	2.128e-33	134.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158351_k127_1117794_0	1048339.KB913029_gene4528	3.782e-183	584.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4ERSJ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158351_k127_1117794_2	479433.Caci_2400	7.551e-72	247.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158351_k127_1117794_1	1123320.KB889665_gene1431	9.604e-149	475.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158351_k127_1117794_3	1229203.KI301992_gene1010	4.079e-56	200.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,3UWBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158351_k127_1126977_1	318424.EU78_11285	6.286e-23	108.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,233W3@1762|Mycobacteriaceae	201174|Actinobacteria	H	Riboflavin biosynthesis	ribD	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158351_k127_1126977_0	645127.ckrop_1046	4.349e-60	209.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,22N5S@1653|Corynebacteriaceae	201174|Actinobacteria	O	peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158351_k127_1130085_0	35754.JNYJ01000014_gene4873	1.03e-17	95.0	COG3468@1|root,COG3637@1|root,COG3468@2|Bacteria,COG3637@2|Bacteria,2IRDI@201174|Actinobacteria,4DF4F@85008|Micromonosporales	201174|Actinobacteria	MU	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158351_k127_1130085_1	1287276.X752_01425	2.188e-14	75.0	COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2TVQN@28211|Alphaproteobacteria,43NPM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158351_k127_113060_0	471852.Tcur_3087	1.123e-146	471.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4EG7B@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158351_k127_113060_4	1157637.KB892090_gene6411	2.51e-32	134.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
SRR25158351_k127_113060_1	1048339.KB913029_gene4641	4.77e-102	347.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4ERQR@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158351_k127_113060_2	106370.Francci3_3121	1.083e-54	194.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4ESRR@85013|Frankiales	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158351_k127_113060_3	2002.JOEQ01000006_gene1464	3.372e-53	190.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria,4EHKP@85012|Streptosporangiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1132980_2	471852.Tcur_0237	1.099e-50	185.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4EIMR@85012|Streptosporangiales	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158351_k127_1132980_1	1463881.KL591017_gene3412	1.207e-91	311.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_1132980_3	67257.JODR01000009_gene372	3.534e-31	126.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158351_k127_1132980_0	105420.BBPO01000047_gene1661	1.048e-219	691.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,2NGRH@228398|Streptacidiphilus	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158351_k127_1150042_0	196162.Noca_2503	2.965e-199	631.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4DNFK@85009|Propionibacteriales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158351_k127_1151264_1	1370121.AUWS01000009_gene5848	1.108e-58	209.0	COG1982@1|root,COG1982@2|Bacteria,2GJ31@201174|Actinobacteria	201174|Actinobacteria	E	Orn Lys Arg decarboxylase	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
SRR25158351_k127_1151264_0	1003195.SCAT_1341	4.043e-155	501.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158351_k127_11588_1	478801.Ksed_13020	2.052e-75	254.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,1ZVIS@145357|Dermacoccaceae	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158351_k127_11588_2	1283283.ATXA01000003_gene1526	4.511e-39	152.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4ESVT@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158351_k127_11588_0	469371.Tbis_1477	6.788e-187	590.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4DYWG@85010|Pseudonocardiales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158351_k127_1164358_2	1120963.KB894491_gene789	4.6e-28	121.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,2Q1FZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158351_k127_1164358_1	1504319.GM45_3740	6.98e-35	136.0	COG2259@1|root,COG2259@2|Bacteria,2IMX8@201174|Actinobacteria	201174|Actinobacteria	S	PFAM DoxX family protein	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158351_k127_1164358_0	1304865.JAGF01000001_gene607	9.095e-51	187.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4F0P6@85016|Cellulomonadaceae	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158351_k127_1164358_4	316274.Haur_4719	0.0009008	48.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158351_k127_1164358_3	1504319.GM45_3755	2.089e-13	71.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,3UWSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158351_k127_1167226_0	1463921.JODF01000075_gene160	9.662e-120	393.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158351_k127_1167226_1	44454.NF84_16395	6.646e-23	102.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria,2342X@1762|Mycobacteriaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158351_k127_117617_0	1081644.IMCC13023_13210	6.207e-118	380.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4FK8Q@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158351_k127_117617_1	1237500.ANBA01000020_gene3239	5.575e-53	192.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4EGP1@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158351_k127_118499_0	1504319.GM45_6205	1.508e-143	459.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,3UW89@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158351_k127_118499_1	1504319.GM45_6210	1.03e-71	245.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,3UWTQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158351_k127_118499_2	1504319.GM45_6215	2.805e-52	188.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,3UWHW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158351_k127_1194354_2	1156844.KB891808_gene1453	2.736e-121	403.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158351_k127_1194354_0	367299.JOEE01000004_gene1053	7.311e-148	477.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4FE6F@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158351_k127_1194354_1	1869.MB27_22590	4.487e-141	458.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4DB1C@85008|Micromonosporales	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158351_k127_1194354_3	1122611.KB903963_gene4735	1.124e-107	357.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4EGI3@85012|Streptosporangiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158351_k127_1194354_4	105425.BBPL01000061_gene5166	1.964e-19	89.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,2NHFW@228398|Streptacidiphilus	201174|Actinobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158351_k127_1200187_2	1394178.AWOO02000052_gene6065	2.517e-89	301.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4EGHW@85012|Streptosporangiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158351_k127_1200187_3	1121020.JIAG01000004_gene1973	5.729e-32	126.0	COG5450@1|root,32SQA@2|Bacteria,2IKJX@201174|Actinobacteria,1W9FF@1268|Micrococcaceae	201174|Actinobacteria	K	Transcription regulator of the Arc MetJ class	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1200187_0	1504319.GM45_0735	2.314e-105	346.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,3UX9Y@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	COG1126 ABC-type polar amino acid transport system, ATPase component	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158351_k127_1200187_1	1504319.GM45_0740	8.956e-99	327.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,3UXJI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG0765 ABC-type amino acid transport system, permease component	-	-	-	ko:K02029,ko:K17074	ko02010,map02010	M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20	-	-	BPD_transp_1,SBP_bac_3
SRR25158351_k127_1204337_0	1089455.MOPEL_011_00140	6.806e-132	428.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4F68W@85018|Dermatophilaceae	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158351_k127_1208342_0	1283287.KB822575_gene72	6.392e-115	374.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNCJ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_1208342_1	443906.CMM_0276	2.872e-61	217.0	COG0637@1|root,COG0637@2|Bacteria,2GMIQ@201174|Actinobacteria,4FSMU@85023|Microbacteriaceae	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158351_k127_1208342_2	1081644.IMCC13023_04840	1.698e-60	214.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,4FP9F@85023|Microbacteriaceae	201174|Actinobacteria	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158351_k127_1209021_1	1123322.KB904660_gene1100	1.298e-72	252.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_1209021_0	1504319.GM45_4270	3.393e-150	482.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,3UW6Z@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_1217244_7	926564.KI911649_gene1765	1.049e-29	121.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4F3S3@85017|Promicromonosporaceae	201174|Actinobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158351_k127_1217244_0	1298863.AUEP01000010_gene4431	3.082e-212	668.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4DNYZ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158351_k127_1217244_4	935866.JAER01000010_gene4137	2.544e-125	407.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4DP92@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N,SAICAR_synt
SRR25158351_k127_1217244_3	1123024.AUII01000006_gene4734	3.804e-131	436.0	COG0028@1|root,COG0028@2|Bacteria,2GKQM@201174|Actinobacteria,4E1T0@85010|Pseudonocardiales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_1217244_1	345341.KUTG_07950	3.409e-211	666.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria,4E00S@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158351_k127_1217244_2	1179773.BN6_37740	1.478e-149	482.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4DYMP@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158351_k127_1217244_5	1504319.GM45_4695	1.256e-69	243.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,3UWSQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1217244_6	1504319.GM45_3460	2.138e-62	226.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,3UXF9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1217453_8	1123320.KB889665_gene1438	1.46e-80	274.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158351_k127_1217453_14	446462.Amir_5239	2.013e-20	95.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4E4HM@85010|Pseudonocardiales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1217453_11	477641.MODMU_3314	4.359e-62	218.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4ESP1@85013|Frankiales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158351_k127_1217453_13	266940.Krad_2991	4.233e-34	132.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158351_k127_1217453_3	1380354.JIAN01000006_gene504	1.561e-133	436.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4F0SE@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158351_k127_1217453_0	58123.JOFJ01000001_gene3103	1.63e-189	599.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4EG6T@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158351_k127_1217453_2	1048339.KB913029_gene3997	6.7e-157	518.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4ERHY@85013|Frankiales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158351_k127_1217453_7	935866.JAER01000002_gene1994	2.816e-82	276.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4DQIB@85009|Propionibacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158351_k127_1217453_6	1123322.KB904705_gene22	3.65e-91	309.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158351_k127_1217453_4	996637.SGM_3785	1.006e-119	399.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158351_k127_1217453_5	1048339.KB913029_gene4006	3.731e-96	319.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4ERMA@85013|Frankiales	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158351_k127_1217453_9	935866.JAER01000002_gene2023	7.162e-77	269.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4DNKD@85009|Propionibacteriales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158351_k127_1217453_10	1463920.JOGB01000018_gene5281	9.397e-71	244.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158351_k127_1217453_1	1123320.KB889596_gene8708	3.462e-184	584.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158351_k127_1217453_12	1095767.CAHD01000208_gene134	1.256e-56	202.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4F2FY@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158351_k127_1217453_15	1463936.JOJI01000075_gene1189	3.032e-12	71.0	COG1404@1|root,COG1404@2|Bacteria,2GMN0@201174|Actinobacteria	201174|Actinobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
SRR25158351_k127_1219372_4	1032480.MLP_16450	1.045e-12	68.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4DNVI@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158351_k127_1219372_1	235985.BBPN01000031_gene2110	4.058e-56	200.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,2NEBS@228398|Streptacidiphilus	201174|Actinobacteria	J	RimM N-terminal domain	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158351_k127_1219372_3	710696.Intca_2292	3.094e-26	109.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4FHEB@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0109 family	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158351_k127_1219372_2	1223543.GP2_001_01250	1.294e-52	192.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4GDSV@85026|Gordoniaceae	201174|Actinobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158351_k127_1219372_0	397278.JOJN01000001_gene2705	1.93e-177	566.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DNUI@85009|Propionibacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158351_k127_1219571_4	1206741.BAFX01000110_gene7522	5.198e-22	100.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4FVNC@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158351_k127_1219571_0	1306174.JODP01000006_gene3800	1.224e-150	487.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158351_k127_1219571_1	313589.JNB_07254	9.072e-112	370.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4FEQ3@85021|Intrasporangiaceae	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158351_k127_1219571_5	402881.Plav_1386	7.621e-22	99.0	COG3339@1|root,COG3339@2|Bacteria,1MZR5@1224|Proteobacteria,2UCIB@28211|Alphaproteobacteria,1JPCY@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1232)	MA20_25305	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158351_k127_1219571_3	1449048.JQKU01000009_gene504	1.165e-84	287.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,234QJ@1762|Mycobacteriaceae	201174|Actinobacteria	G	Inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_1219571_2	1504319.GM45_0025	7.637e-94	322.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,3UWWV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Cytochrome P450	cyp132	-	-	ko:K21164	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	p450
SRR25158351_k127_1227680_0	1504319.GM45_1140	1.122e-62	226.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,3UX8T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158351_k127_1227680_1	1079986.JH164897_gene7895	2.402e-20	97.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria	201174|Actinobacteria	G	PfkB family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1243520_1	1122609.AUGT01000020_gene1022	4.4e-65	231.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4DQT3@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158351_k127_1243520_0	384765.SIAM614_10738	2.069e-229	716.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158351_k127_1251782_3	1385519.N801_02810	7.415e-65	222.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4FEI3@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158351_k127_1251782_2	1043205.AFYF01000053_gene3079	4.082e-134	438.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4FFGK@85021|Intrasporangiaceae	201174|Actinobacteria	J	tRNA-dihydrouridine synthase	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158351_k127_1251782_1	1121019.AUMN01000014_gene4129	1.429e-139	454.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,1W7KN@1268|Micrococcaceae	201174|Actinobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158351_k127_1251782_0	1504319.GM45_0350	4.692e-161	514.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158351_k127_1253119_0	469371.Tbis_0506	5.452e-50	183.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4DXHD@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158351_k127_1253119_1	1172188.KB911830_gene3827	2.847e-37	145.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4FFG5@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158351_k127_1253348_3	1206726.BAFV01000003_gene223	1.554e-14	79.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4FWC3@85025|Nocardiaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158351_k127_1253348_2	561175.KB894099_gene5138	6.054e-70	237.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4EJ9N@85012|Streptosporangiales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158351_k127_1253348_0	367299.JOEE01000001_gene2166	3.663e-84	281.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4FFIZ@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158351_k127_1253348_1	1122611.KB903951_gene6341	5.927e-73	246.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4EH47@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_1255684_1	479435.Kfla_3086	9.081e-58	206.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,4DPPY@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158351_k127_1255684_2	710696.Intca_1655	2.988e-42	158.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4FGPR@85021|Intrasporangiaceae	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158351_k127_1255684_0	1283283.ATXA01000003_gene1520	1.359e-285	902.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4ES9K@85013|Frankiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158351_k127_1255684_3	103733.JNYO01000013_gene4212	4.475e-40	150.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4DYWG@85010|Pseudonocardiales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158351_k127_1267853_2	1352941.M877_34005	2.322e-21	102.0	COG2367@1|root,COG2367@2|Bacteria,2GKPU@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRR25158351_k127_1267853_1	446469.Sked_07970	1.904e-27	119.0	COG1876@1|root,COG1876@2|Bacteria,2IHUG@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	-	-	-	-	-	-	-	-	-	-	VanY
SRR25158351_k127_1267853_0	714943.Mucpa_6587	5.071e-57	213.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1IPI3@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158351_k127_1274553_0	1968.JOEV01000009_gene1781	3.7e-141	456.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria	201174|Actinobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158351_k127_1275338_3	1089551.KE386572_gene3993	2.467e-06	50.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TSBY@28211|Alphaproteobacteria,4BPDN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsE	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158351_k127_1275338_0	1236902.ANAS01000042_gene2247	2.279e-109	361.0	COG0685@1|root,COG0685@2|Bacteria,2GJ6U@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158351_k127_1275338_1	1236902.ANAS01000042_gene2248	2.502e-46	169.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
SRR25158351_k127_1275338_2	2074.JNYD01000002_gene5788	3.556e-30	120.0	COG5012@1|root,COG5012@2|Bacteria,2IEGQ@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158351_k127_1277290_2	1713.JOFV01000004_gene3442	6.07e-102	346.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4F1WF@85016|Cellulomonadaceae	201174|Actinobacteria	M	Peptidase family M50	rip1	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158351_k127_1277290_1	1122138.AQUZ01000010_gene5084	2.514e-150	485.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4DND1@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158351_k127_1277290_0	1348663.KCH_52900	8.978e-173	548.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,2M1NX@2063|Kitasatospora	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.9	ko:K00128,ko:K00131	ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00135,M00308,M00633	R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1278973_4	211165.AJLN01000153_gene666	6.243e-31	126.0	COG0454@1|root,COG0456@2|Bacteria,1G5YW@1117|Cyanobacteria,1JM9F@1189|Stigonemataceae	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1278973_5	1123013.AUIC01000002_gene1204	6.928e-21	96.0	COG0695@1|root,COG0695@2|Bacteria,2GQ85@201174|Actinobacteria,4FQ09@85023|Microbacteriaceae	201174|Actinobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158351_k127_1278973_0	1043493.BBLU01000002_gene1600	1.024e-245	765.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158351_k127_1278973_2	710696.Intca_2027	1.516e-37	146.0	COG1714@1|root,COG1714@2|Bacteria,2IQMG@201174|Actinobacteria,4FHT2@85021|Intrasporangiaceae	201174|Actinobacteria	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158351_k127_1278973_1	1120950.KB892707_gene4748	3.906e-51	189.0	2AUFS@1|root,31K3Y@2|Bacteria,2GIXC@201174|Actinobacteria,4DQHR@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4191
SRR25158351_k127_1278973_3	1229203.KI301992_gene777	8.279e-37	139.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,3UWD6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158351_k127_128405_0	66373.JOFQ01000001_gene2098	9.792e-87	300.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the GcvT family	soxA	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
SRR25158351_k127_1290389_0	1172188.KB911828_gene4047	1.829e-28	120.0	28J4D@1|root,2Z90C@2|Bacteria,2GJYC@201174|Actinobacteria,4FK0K@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
SRR25158351_k127_1290389_1	479433.Caci_2022	6.517e-18	87.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158351_k127_1290389_2	1122939.ATUD01000005_gene2787	5.23e-14	77.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4CSVZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
SRR25158351_k127_1291740_1	1172180.KB911785_gene285	4.924e-72	251.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158351_k127_1291740_0	351607.Acel_1263	1.346e-75	259.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4ES9C@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158351_k127_1320008_10	1122611.KB903978_gene3345	5.707e-09	57.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4EI9C@85012|Streptosporangiales	201174|Actinobacteria	D	Cell cycle protein	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
SRR25158351_k127_1320008_2	287986.DV20_27600	1.262e-111	371.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4DY3X@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158351_k127_1320008_1	1048339.KB913029_gene4575	2.826e-146	477.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4ERUC@85013|Frankiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_1320008_8	58123.JOFJ01000001_gene3037	1.421e-23	109.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4EJPJ@85012|Streptosporangiales	201174|Actinobacteria	M	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158351_k127_1320008_0	471853.Bcav_2407	3.057e-161	517.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158351_k127_1320008_5	1033730.CAHG01000016_gene440	5.485e-35	142.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4DR2J@85009|Propionibacteriales	201174|Actinobacteria	S	Multi-copper polyphenol oxidoreductase laccase	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158351_k127_1320008_3	1048339.KB913029_gene4571	2.327e-71	247.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4ESQN@85013|Frankiales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158351_k127_1320008_4	1048339.KB913029_gene4570	2.114e-43	163.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4ESVW@85013|Frankiales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158351_k127_1320008_6	1089455.MOPEL_032_00070	3.657e-29	118.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4F798@85018|Dermatophilaceae	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158351_k127_1320008_9	298654.FraEuI1c_2381	2.296e-21	104.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4ET2B@85013|Frankiales	201174|Actinobacteria	D	PFAM DivIVA family protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158351_k127_1320008_7	1236902.ANAS01000017_gene2226	1.441e-28	117.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4EHRZ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158351_k127_1323000_2	529884.Rhola_00013130	1.606e-24	104.0	2B2E6@1|root,31UYR@2|Bacteria,2GUPA@201174|Actinobacteria,4FSK3@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1323000_0	1449347.JQLN01000001_gene125	3.417e-52	196.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,2M3NJ@2063|Kitasatospora	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158351_k127_1323000_1	1121877.JQKF01000014_gene16	5.24e-36	144.0	COG0673@1|root,COG0673@2|Bacteria,2HFKH@201174|Actinobacteria,4CP3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158351_k127_1323935_5	529884.Rhola_00006450	3.861e-08	56.0	COG3375@1|root,COG3375@2|Bacteria,2I8MV@201174|Actinobacteria,4FPQ8@85023|Microbacteriaceae	201174|Actinobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158351_k127_1323935_0	529884.Rhola_00006460	3.449e-208	651.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4FM9M@85023|Microbacteriaceae	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158351_k127_1323935_4	529884.Rhola_00013700	3.805e-30	124.0	COG2020@1|root,COG2020@2|Bacteria,2HTD4@201174|Actinobacteria,4FT14@85023|Microbacteriaceae	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158351_k127_1323935_3	1504319.GM45_1895	6.198e-47	171.0	2AWFS@1|root,31NC1@2|Bacteria,2IMS0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1323935_1	247156.NFA_11120	3.448e-90	309.0	COG0387@1|root,COG0387@2|Bacteria,2GJWT@201174|Actinobacteria,4FWF9@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/calcium exchanger protein	chaA	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iNJ661.Rv1607	Na_Ca_ex
SRR25158351_k127_1323935_2	1032480.MLP_15560	5.683e-85	285.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DPAN@85009|Propionibacteriales	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158351_k127_1329754_3	67356.KL575664_gene3304	2.757e-38	148.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria	201174|Actinobacteria	K	ATPase or kinase	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158351_k127_1329754_2	457425.XNR_3789	6.855e-40	155.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Peptidase M22, glycoprotease	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158351_k127_1329754_4	28444.JODQ01000002_gene4367	1.725e-31	128.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4EJP4@85012|Streptosporangiales	201174|Actinobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158351_k127_1329754_0	196162.Noca_3657	4.454e-155	496.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4DP6P@85009|Propionibacteriales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158351_k127_1329754_1	1379270.AUXF01000002_gene1288	1.7e-80	278.0	COG2040@1|root,COG2040@2|Bacteria	2|Bacteria	E	homocysteine	mmuM	GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
SRR25158351_k127_1329754_5	649754.HMPREF0281_00960	1.473e-13	77.0	28VVC@1|root,2ZHWX@2|Bacteria,2GQFA@201174|Actinobacteria,22N7V@1653|Corynebacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
SRR25158351_k127_133314_0	266940.Krad_3278	1.027e-222	698.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_133314_1	471856.Jden_1466	1.159e-09	59.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158351_k127_1334577_0	1504319.GM45_6200	0.0	1278.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,3UWEZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158351_k127_133621_0	2074.JNYD01000026_gene622	5.942e-31	130.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158351_k127_1343349_0	392500.Swoo_0198	7.234e-101	347.0	COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,2QAGA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
SRR25158351_k127_1351866_3	1120950.KB892740_gene2543	2.472e-47	175.0	2CQNK@1|root,323RQ@2|Bacteria,2I83S@201174|Actinobacteria,4DUMK@85009|Propionibacteriales	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR25158351_k127_1351866_0	1504319.GM45_1640	4.427e-184	599.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,3UX6W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Transglycosylase	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158351_k127_1351866_2	67352.JODS01000003_gene1942	8.014e-52	198.0	COG0787@1|root,COG0787@2|Bacteria,2GJJX@201174|Actinobacteria	201174|Actinobacteria	M	Alanine racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158351_k127_1351866_1	1348663.KCH_39330	7.323e-126	411.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,2M0RF@2063|Kitasatospora	201174|Actinobacteria	V	FemAB family	femX	-	2.3.2.10	ko:K05363	ko00550,ko01100,map00550,map01100	-	R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
SRR25158351_k127_1354065_10	1122622.ATWJ01000008_gene2645	4.511e-15	78.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4FG0N@85021|Intrasporangiaceae	201174|Actinobacteria	CO	Thiol disulfide interchange protein	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158351_k127_1354065_7	235985.BBPN01000024_gene1691	1.111e-72	253.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,2NG1Q@228398|Streptacidiphilus	201174|Actinobacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158351_k127_1354065_2	1048339.KB913029_gene2341	2.283e-131	435.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4ERPQ@85013|Frankiales	201174|Actinobacteria	O	PFAM ResB family protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158351_k127_1354065_3	351607.Acel_0254	2.172e-91	310.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4ESE9@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158351_k127_1354065_5	1385520.N802_08960	1.053e-87	298.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4FF0S@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158351_k127_1354065_6	994479.GL877879_gene6216	1.024e-73	264.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4DYFK@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_1354065_1	65497.JODV01000007_gene534	2.78e-146	468.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4E09A@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_1354065_8	345341.KUTG_03563	1.768e-68	245.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4DYA4@85010|Pseudonocardiales	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
SRR25158351_k127_1354065_4	188626.HMPREF0321_1248	2.807e-91	320.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,1ZVK1@145357|Dermacoccaceae	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158351_k127_1354065_9	1504319.GM45_0730	2.814e-54	201.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158351_k127_1354065_0	469383.Cwoe_2246	6.786e-155	499.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria,2GKVH@201174|Actinobacteria,4CRRI@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3
SRR25158351_k127_1355326_0	471852.Tcur_1023	0.0	1180.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4EH06@85012|Streptosporangiales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158351_k127_1359242_1	258052.JNYV01000001_gene401	5.923e-08	55.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,2M18H@2063|Kitasatospora	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158351_k127_1359242_0	749927.AMED_2701	8.843e-212	665.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4E0SI@85010|Pseudonocardiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_1362952_0	1122182.KB903837_gene3899	6.057e-100	334.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D987@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_1362952_3	1313172.YM304_23250	8.094e-46	175.0	COG0730@1|root,COG0730@2|Bacteria,2HGFT@201174|Actinobacteria,4CNDC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158351_k127_1362952_2	1033730.CAHG01000006_gene1028	7.069e-58	205.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158351_k127_1362952_1	1504319.GM45_0745	1.238e-97	327.0	COG0834@1|root,COG0834@2|Bacteria,2HFUI@201174|Actinobacteria,3UXRH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
SRR25158351_k127_1362952_4	1504319.GM45_0740	9.898e-17	83.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,3UXJI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG0765 ABC-type amino acid transport system, permease component	-	-	-	ko:K02029,ko:K17074	ko02010,map02010	M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20	-	-	BPD_transp_1,SBP_bac_3
SRR25158351_k127_1368356_0	1449347.JQLN01000007_gene2154	8.7e-276	856.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,2M1WP@2063|Kitasatospora	201174|Actinobacteria	C	Aconitase C-terminal domain	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158351_k127_1368356_1	58123.JOFJ01000005_gene1427	1.636e-88	306.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4EG7S@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158351_k127_1368356_2	28444.JODQ01000007_gene5625	1.127e-51	185.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4EH63@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158351_k127_1377643_1	469371.Tbis_0898	1.941e-203	638.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4E0X3@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158351_k127_1377643_2	1157637.KB892146_gene7146	9.64e-106	351.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158351_k127_1377643_0	1504319.GM45_6105	3.984e-256	794.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,3UW86@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158351_k127_1377643_4	1120959.ATXF01000004_gene3089	9.594e-23	99.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria,4FQ12@85023|Microbacteriaceae	201174|Actinobacteria	C	ATP synthase, Delta/Epsilon chain, beta-sandwich domain	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158351_k127_1377643_3	426716.JOAJ01000011_gene6439	7.735e-31	130.0	COG2186@1|root,COG2186@2|Bacteria,2GKJM@201174|Actinobacteria,4G015@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158351_k127_1377643_5	1463825.JNXC01000022_gene618	6.312e-12	75.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2GJYH@201174|Actinobacteria,4DZ1X@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
SRR25158351_k127_1380680_1	100226.SCO2386	3.346e-41	159.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria	201174|Actinobacteria	QT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158351_k127_1380680_0	1386089.N865_07825	3.165e-92	308.0	COG0331@1|root,COG0511@1|root,COG0331@2|Bacteria,COG0511@2|Bacteria,2GME0@201174|Actinobacteria,4FFAJ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Biotin attachment protein	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158351_k127_1381490_0	1173020.Cha6605_0480	5.095e-17	81.0	COG0053@1|root,COG0053@2|Bacteria,1G0RT@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158351_k127_1381490_1	1122138.AQUZ01000007_gene3164	1.024e-14	78.0	2E65S@1|root,330UF@2|Bacteria,2IMEQ@201174|Actinobacteria,4DSE6@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
SRR25158351_k127_1381490_2	1894.JOER01000011_gene1907	1.578e-14	83.0	COG3346@1|root,COG3346@2|Bacteria,2GMGB@201174|Actinobacteria	201174|Actinobacteria	S	SURF1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158351_k127_1391700_0	1048339.KB913029_gene2921	8.237e-95	327.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4ES9T@85013|Frankiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158351_k127_1397519_3	1120950.KB892741_gene2656	7.708e-111	366.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4DNKM@85009|Propionibacteriales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158351_k127_1397519_6	1114959.SZMC14600_04598	1.503e-31	126.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4E4D6@85010|Pseudonocardiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158351_k127_1397519_1	1386089.N865_06515	4.972e-237	741.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4FFVV@85021|Intrasporangiaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158351_k127_1397519_2	235985.BBPN01000056_gene7831	5.726e-230	721.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,2NGDR@228398|Streptacidiphilus	201174|Actinobacteria	J	GatB domain	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158351_k127_1397519_4	517722.AEUE01000008_gene211	3.008e-89	311.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2K0M0@204457|Sphingomonadales	204457|Sphingomonadales	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158351_k127_1397519_5	1122138.AQUZ01000078_gene6141	2.218e-77	269.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DNYY@85009|Propionibacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_1397519_0	743718.Isova_2187	8.264e-289	894.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4F3NX@85017|Promicromonosporaceae	201174|Actinobacteria	H	Dehydratase family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158351_k127_1397519_7	266940.Krad_0666	9.256e-08	58.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	ybjJ	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1412984_0	105425.BBPL01000031_gene4462	4.628e-155	499.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,2NFDA@228398|Streptacidiphilus	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158351_k127_1412984_1	710696.Intca_1209	1.902e-67	234.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4FK0I@85021|Intrasporangiaceae	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158351_k127_1416272_2	1121385.AQXW01000003_gene356	2.898e-39	152.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,1ZVC7@145357|Dermacoccaceae	201174|Actinobacteria	E	NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158351_k127_1416272_0	529884.Rhola_00012610	2.023e-85	287.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4FNU2@85023|Microbacteriaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158351_k127_1416272_1	1193181.BN10_650014	7.548e-63	220.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4FGNS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158351_k127_1420847_1	55952.BU52_19670	3.065e-63	221.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158351_k127_1420847_0	1283283.ATXA01000002_gene2425	6.455e-100	332.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4ERM5@85013|Frankiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158351_k127_1421434_9	1304865.JAGF01000001_gene1127	2.885e-21	100.0	COG1277@1|root,COG1277@2|Bacteria,2IMF1@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158351_k127_1421434_3	1229780.BN381_10026	5.013e-42	159.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,3UWPM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158351_k127_1421434_2	680198.SCAB_76471	2.819e-47	181.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1421434_5	1283287.KB822575_gene231	3.199e-34	139.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4DRWZ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158351_k127_1421434_10	1304865.JAGF01000001_gene605	4.376e-06	55.0	2DP6P@1|root,330SA@2|Bacteria,2GQYA@201174|Actinobacteria,4F1HS@85016|Cellulomonadaceae	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
SRR25158351_k127_1421434_4	1122609.AUGT01000020_gene1052	1.265e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,2IRVN@201174|Actinobacteria,4DVTP@85009|Propionibacteriales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1421434_6	1210045.ALNP01000001_gene3259	1.051e-26	111.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria	201174|Actinobacteria	H	PFAM thiamineS protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_1421434_1	1304865.JAGF01000001_gene581	8.286e-54	205.0	COG2223@1|root,COG2223@2|Bacteria,2I6BY@201174|Actinobacteria	201174|Actinobacteria	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1421434_8	479435.Kfla_2109	9.307e-24	102.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4DRJS@85009|Propionibacteriales	201174|Actinobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158351_k127_1421434_7	1121019.AUMN01000009_gene1841	5.39e-24	104.0	COG2076@1|root,COG2076@2|Bacteria,2IKQZ@201174|Actinobacteria	201174|Actinobacteria	P	Multidrug resistance protein	mmr	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR25158351_k127_1421434_0	1380356.JNIK01000011_gene1758	3.115e-295	912.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4ERKH@85013|Frankiales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_1423631_2	1122609.AUGT01000022_gene709	3.978e-26	113.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,4DRA1@85009|Propionibacteriales	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158351_k127_1423631_1	1120950.KB892747_gene3693	5.882e-123	402.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4DN47@85009|Propionibacteriales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158351_k127_1423631_0	1504319.GM45_4590	6.747e-139	457.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,3UW6W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158351_k127_1424470_0	188626.HMPREF0321_1722	3.492e-94	317.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,1ZVSH@145357|Dermacoccaceae	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158351_k127_1424470_1	298654.FraEuI1c_0376	4.431e-56	200.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4ERXA@85013|Frankiales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158351_k127_1441350_1	1079986.JH164873_gene2997	8.967e-168	531.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158351_k127_1441350_4	1179773.BN6_77490	7.309e-59	206.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,4E3HK@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM succinate dehydrogenase, cytochrome b556 subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158351_k127_1441350_5	471857.Svir_05370	5.091e-58	204.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,4E2T2@85010|Pseudonocardiales	201174|Actinobacteria	C	Succinate dehydrogenase, hydrophobic anchor subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158351_k127_1441350_0	1123320.KB889688_gene406	9.41e-321	987.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158351_k127_1441350_2	1123052.AUDF01000005_gene1043	1.204e-126	409.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4FK5B@85023|Microbacteriaceae	201174|Actinobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
SRR25158351_k127_1441350_6	996306.SSUR61_0241	1.314e-52	192.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HQUJ@91061|Bacilli,1WT1I@1307|Streptococcus suis	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	XK27_05175	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158351_k127_1441350_3	1048339.KB913029_gene2835	1.971e-82	279.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4ES9F@85013|Frankiales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158351_k127_1444454_0	1123320.KB889698_gene9327	1.89e-135	438.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158351_k127_1444454_1	436229.JOEH01000016_gene7074	1.99e-83	280.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,2NEWI@228398|Streptacidiphilus	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158351_k127_1447658_1	1504319.GM45_1020	1.105e-12	77.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,3UXB3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI2	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158351_k127_1447658_0	1150864.MILUP08_45165	1.537e-70	245.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4D8QG@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158351_k127_1452391_2	1101188.KI912155_gene2223	1.88e-60	211.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,1W8H7@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gbsA	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1452391_1	2002.JOEQ01000044_gene829	3.106e-137	444.0	COG4175@1|root,COG4175@2|Bacteria,2GJC0@201174|Actinobacteria,4EGWC@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158351_k127_1452391_0	285514.JNWO01000007_gene3505	2.7e-180	585.0	COG4176@1|root,COG4176@2|Bacteria,2GKRF@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system permease component	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158351_k127_14525_5	1504319.GM45_2695	1.075e-49	180.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,3UWQZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158351_k127_14525_4	1048339.KB913029_gene2732	6.246e-64	227.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4ESM1@85013|Frankiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158351_k127_14525_1	1385521.N803_04315	8.339e-115	373.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4FEH9@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158351_k127_14525_3	1121372.AULK01000004_gene1132	7.906e-72	244.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4FNGC@85023|Microbacteriaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158351_k127_14525_2	1454010.JEOE01000017_gene1270	5.799e-79	274.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4F0TZ@85016|Cellulomonadaceae	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158351_k127_14525_9	67352.JODS01000006_gene6409	9.499e-13	70.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158351_k127_14525_0	235985.BBPN01000023_gene2615	1.377e-210	659.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,2NHQV@228398|Streptacidiphilus	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_14525_7	710111.FraQA3DRAFT_3646	8.685e-28	128.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4ERDT@85013|Frankiales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158351_k127_14525_10	1095767.CAHD01000170_gene2528	4.182e-09	65.0	COG1261@1|root,COG1261@2|Bacteria,2GR8T@201174|Actinobacteria,4F1CP@85016|Cellulomonadaceae	201174|Actinobacteria	NO	PFAM SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
SRR25158351_k127_14525_8	1120950.KB892764_gene5603	1.41e-18	93.0	2DPN9@1|root,332RH@2|Bacteria,2GVN7@201174|Actinobacteria,4DSF3@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_14525_6	196162.Noca_1440	2.958e-33	131.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4DPEU@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158351_k127_1453219_0	1123320.KB889685_gene2191	1.853e-193	610.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria	201174|Actinobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158351_k127_1453219_1	1035308.AQYY01000001_gene2901	1.716e-174	552.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,260TY@186807|Peptococcaceae	186801|Clostridia	C	Aconitase family (aconitate hydratase)	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158351_k127_1459977_1	1343740.M271_46745	2.152e-50	186.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria	201174|Actinobacteria	E	succinyl-diaminopimelate desuccinylase	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158351_k127_1459977_0	1134445.AJJM01000166_gene781	2.527e-123	403.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
SRR25158351_k127_1468329_4	1504319.GM45_3100	6.868e-52	188.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,3UWPU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158351_k127_1468329_3	500153.JOEK01000013_gene1628	1.044e-81	280.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158351_k127_1468329_1	1906.SFRA_14765	2.562e-124	406.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158351_k127_1468329_0	1122609.AUGT01000006_gene1552	3.188e-148	479.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DN8T@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158351_k127_1468329_2	1048339.KB913029_gene127	1.48e-87	303.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,4ERQE@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_1468329_5	935839.JAGJ01000002_gene903	9.214e-30	119.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4F34W@85017|Promicromonosporaceae	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158351_k127_1474717_2	469371.Tbis_0469	1.222e-60	217.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4DYPT@85010|Pseudonocardiales	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158351_k127_1474717_1	500153.JOEK01000004_gene784	1.748e-71	256.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria	201174|Actinobacteria	M	Mur ligase, middle domain protein	murE	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158351_k127_1474717_3	1504319.GM45_0715	1.186e-30	124.0	2D9MJ@1|root,32SZC@2|Bacteria,2I8AM@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	-	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
SRR25158351_k127_1474717_0	446471.Xcel_2015	1.231e-255	794.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4F3NG@85017|Promicromonosporaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158351_k127_1477428_0	258533.BN977_00329	2.36e-79	276.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,232VV@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158351_k127_1479084_1	1089544.KB912942_gene4999	4.146e-09	64.0	COG0476@1|root,COG0476@2|Bacteria,2GMJI@201174|Actinobacteria,4E1XH@85010|Pseudonocardiales	201174|Actinobacteria	H	Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158351_k127_1479084_0	585530.HMPREF0183_0321	3.295e-117	391.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4F8CC@85019|Brevibacteriaceae	201174|Actinobacteria	L	HRDC domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158351_k127_1479105_1	2002.JOEQ01000015_gene4974	7.811e-74	255.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4EHKT@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158351_k127_1479105_0	1123320.KB889562_gene6860	4.291e-177	567.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158351_k127_1479525_0	1120950.KB892708_gene4316	0.0	1102.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4DNSQ@85009|Propionibacteriales	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158351_k127_1481766_0	1348338.ADILRU_0568	3.296e-169	541.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4FMA5@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158351_k127_1481766_1	1223542.GM1_010_00380	1.698e-50	183.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4GDU6@85026|Gordoniaceae	201174|Actinobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158351_k127_1481766_2	1048339.KB913029_gene4333	6.067e-28	113.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4ESWH@85013|Frankiales	201174|Actinobacteria	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158351_k127_1483411_1	935866.JAER01000022_gene2945	8.809e-31	128.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4DQDM@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158351_k127_1483411_0	2002.JOEQ01000027_gene7987	2.019e-183	586.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EG2W@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	GO:0000988,GO:0000990,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158351_k127_1489193_0	28444.JODQ01000002_gene4308	1.909e-194	609.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4EFHD@85012|Streptosporangiales	201174|Actinobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158351_k127_1489193_1	1122182.KB903813_gene2509	3.553e-171	541.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4DC08@85008|Micromonosporales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158351_k127_1489193_2	1120950.KB892760_gene5727	0.0005763	44.0	2DRQP@1|root,33CNM@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3017
SRR25158351_k127_1491897_1	1210045.ALNP01000017_gene1831	5.888e-157	498.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria	201174|Actinobacteria	H	The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158351_k127_1491897_3	270374.MELB17_04972	6.946e-37	141.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1SCYV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
SRR25158351_k127_1491897_4	521003.COLINT_03369	1.559e-27	113.0	COG3549@1|root,COG3549@2|Bacteria,2GRHN@201174|Actinobacteria	201174|Actinobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
SRR25158351_k127_1491897_2	28444.JODQ01000008_gene1197	1.193e-142	481.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4EHD3@85012|Streptosporangiales	201174|Actinobacteria	I	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158351_k127_1491897_0	1123320.KB889672_gene3705	7.075e-209	684.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158351_k127_1495855_0	1210045.ALNP01000002_gene3944	1.877e-83	279.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158351_k127_1495855_1	1454010.JEOE01000049_gene2697	1.815e-17	91.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
SRR25158351_k127_1497534_0	351607.Acel_1054	0.0	1553.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERD2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158351_k127_1497534_2	1509403.GW12_17390	5.627e-49	179.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,3NN9F@468|Moraxellaceae	1236|Gammaproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158351_k127_1497534_1	469371.Tbis_1438	1.353e-107	354.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4DZTD@85010|Pseudonocardiales	201174|Actinobacteria	E	imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158351_k127_1497534_3	1137269.AZWL01000008_gene4793	6.991e-27	111.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria	201174|Actinobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158351_k127_1500430_3	639282.DEFDS_2077	9.766e-49	178.0	COG2185@1|root,COG2185@2|Bacteria,2GGDT@200930|Deferribacteres	200930|Deferribacteres	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158351_k127_1500430_4	1463841.JOIR01000004_gene6339	1.096e-28	128.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158351_k127_1500430_0	67315.JOBD01000028_gene2122	2.946e-282	889.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158351_k127_1500430_2	351607.Acel_0374	1.162e-81	280.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4ESNR@85013|Frankiales	201174|Actinobacteria	S	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158351_k127_1500430_5	1304865.JAGF01000001_gene590	4.642e-23	102.0	2E4PN@1|root,32ZIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1500430_1	1122182.KB903813_gene2467	8.63e-247	769.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4DAVN@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158351_k127_1501553_1	1214101.BN159_6530	1.572e-177	569.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158351_k127_1501553_0	408672.NBCG_01444	1.551e-184	580.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN4J@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158351_k127_1506972_0	526227.Mesil_1969	8.384e-91	310.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	puuB	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
SRR25158351_k127_1518999_1	1283283.ATXA01000006_gene1821	8.767e-122	394.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4ERMZ@85013|Frankiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158351_k127_1518999_6	561175.KB894099_gene4966	2.04e-63	220.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4EJ96@85012|Streptosporangiales	201174|Actinobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3581c	YgbB
SRR25158351_k127_1518999_8	1283283.ATXA01000006_gene1817	2.898e-53	195.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158351_k127_1518999_5	28042.GU90_15635	3.704e-66	228.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4DXYN@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158351_k127_1518999_7	529884.Rhola_00001880	7.356e-63	218.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4FNQ6@85023|Microbacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158351_k127_1518999_2	465515.Mlut_03750	1.553e-93	311.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,1W7VB@1268|Micrococcaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1518999_3	1463864.JOGO01000126_gene3472	7.814e-80	279.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158351_k127_1518999_4	1306174.JODP01000006_gene3380	1.487e-69	243.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158351_k127_1518999_0	1348663.KCH_35520	1.015e-167	536.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,2M1NV@2063|Kitasatospora	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1518999_9	196162.Noca_4049	5.049e-27	115.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4DQQM@85009|Propionibacteriales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158351_k127_1521616_3	1504319.GM45_0020	8.512e-39	149.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,3UXCY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158351_k127_1521616_2	1504319.GM45_3310	4.643e-111	368.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	COesterase,DUF2920,Peptidase_S9
SRR25158351_k127_1521616_1	67332.FM21_36275	5.704e-139	454.0	COG1232@1|root,COG1232@2|Bacteria,2HJ1C@201174|Actinobacteria	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158351_k127_1521616_0	1504319.GM45_2880	4.115e-177	565.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,3UX38@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NAD(P) transhydrogenase beta subunit	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158351_k127_1521616_4	1122138.AQUZ01000021_gene8593	2.435e-34	134.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4DRSV@85009|Propionibacteriales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158351_k127_1521616_5	1123400.KB904791_gene38	1.049e-11	68.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158351_k127_1527078_0	1048339.KB913029_gene4399	3.358e-180	567.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ERXD@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158351_k127_1527078_1	350058.Mvan_1164	1.106e-114	378.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,237CF@1762|Mycobacteriaceae	201174|Actinobacteria	P	membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158351_k127_1527078_2	40571.JOEA01000008_gene2570	1.432e-57	207.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DYPS@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158351_k127_1533054_0	1120950.KB892707_gene4731	4.841e-117	379.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4DNNP@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158351_k127_1533054_1	446468.Ndas_0925	1.317e-29	122.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4EG82@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158351_k127_1533513_1	446466.Cfla_0566	5.854e-79	269.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4F1T5@85016|Cellulomonadaceae	201174|Actinobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158351_k127_1533513_0	1121385.AQXW01000004_gene2217	4.165e-92	309.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria,1ZWPJ@145357|Dermacoccaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1533513_2	1050202.KB913024_gene978	8.635e-50	183.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,408VK@622450|Actinopolysporales	201174|Actinobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158351_k127_1534281_1	1397278.AYMV01000007_gene323	1.94e-144	460.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FK99@85023|Microbacteriaceae	201174|Actinobacteria	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158351_k127_1534281_5	1504319.GM45_0220	7.399e-46	169.0	COG4270@1|root,COG4270@2|Bacteria,2IQJ5@201174|Actinobacteria,3UWXT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158351_k127_1534281_3	529884.Rhola_00012080	7.671e-115	374.0	COG5524@1|root,COG5524@2|Bacteria,2IGYM@201174|Actinobacteria,4FNCU@85023|Microbacteriaceae	201174|Actinobacteria	S	Bacteriorhodopsin-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhodopsin
SRR25158351_k127_1534281_0	1504319.GM45_5725	2.544e-166	535.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,3UW9E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158351_k127_1534281_2	1504319.GM45_3610	2.924e-119	389.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1534281_4	28042.GU90_15825	3.266e-52	194.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,4DY5I@85010|Pseudonocardiales	201174|Actinobacteria	E	Lysophospholipase L1-like esterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158351_k127_1534281_6	1449069.JMLO01000003_gene3944	1.137e-11	65.0	COG0695@1|root,COG0695@2|Bacteria,2IQF9@201174|Actinobacteria,4G328@85025|Nocardiaceae	201174|Actinobacteria	O	Glutaredoxin	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
SRR25158351_k127_1538479_0	1081644.IMCC13023_05080	8.386e-155	499.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4FKGA@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158351_k127_1538479_1	1122611.KB904007_gene7846	2.67e-86	292.0	COG1028@1|root,COG1028@2|Bacteria,2GKE1@201174|Actinobacteria,4EHUZ@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1538479_2	1035308.AQYY01000001_gene3239	1.42e-29	121.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
SRR25158351_k127_1538479_3	479431.Namu_0355	4.352e-14	74.0	2EGTM@1|root,33AJR@2|Bacteria,2GWY1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1539529_0	1504319.GM45_3570	1.247e-159	506.0	COG1012@1|root,COG1012@2|Bacteria,2HEX0@201174|Actinobacteria,3UWBJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158351_k127_1539529_1	641107.CDLVIII_1012	2.863e-08	58.0	28I63@1|root,2Z897@2|Bacteria,1V1EH@1239|Firmicutes,24EDP@186801|Clostridia,36IG5@31979|Clostridiaceae	186801|Clostridia	S	Amino acid synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AA_synth
SRR25158351_k127_1542484_0	1906.SFRA_00025	5.278e-98	335.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria	201174|Actinobacteria	H	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158351_k127_1542484_1	981369.JQMJ01000004_gene5942	2.242e-35	142.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,2NFR1@228398|Streptacidiphilus	201174|Actinobacteria	S	SprT-like family	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158351_k127_1542484_2	591158.SSMG_00932	2.558e-06	56.0	COG0476@1|root,COG0476@2|Bacteria,2GMJI@201174|Actinobacteria	201174|Actinobacteria	H	UBA ThiF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158351_k127_1544181_0	1288083.AUKR01000013_gene765	1.576e-145	479.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria	201174|Actinobacteria	T	UPF0182 protein	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158351_k127_1544181_1	67315.JOBD01000024_gene1538	6.205e-38	148.0	2DA1Q@1|root,32TUF@2|Bacteria,2GKR3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1544181_2	1123052.AUDF01000001_gene1701	2.139e-34	134.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4FK7Z@85023|Microbacteriaceae	201174|Actinobacteria	T	Lon protease (S16) C-terminal proteolytic domain	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158351_k127_15470_1	979556.MTES_1460	1.227e-77	269.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria,4FN5W@85023|Microbacteriaceae	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_15470_0	926564.KI911694_gene935	1.631e-79	273.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
SRR25158351_k127_15470_2	388413.ALPR1_13345	4.487e-11	65.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,47P3T@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR25158351_k127_1549407_1	1203605.HMPREF1531_02079	1.05e-39	149.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4DNY4@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158351_k127_1549407_2	66373.JOFQ01000017_gene1335	2.815e-20	99.0	COG0505@1|root,COG0505@2|Bacteria,2GM9I@201174|Actinobacteria	201174|Actinobacteria	EF	Belongs to the CarA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1549407_0	1033730.CAHG01000016_gene594	2.501e-91	303.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4DMZJ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158351_k127_155021_0	1504319.GM45_4290	1.479e-158	507.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,3UW9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
SRR25158351_k127_155021_2	1298860.AUEM01000005_gene2736	4.722e-07	51.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158351_k127_155021_1	1304865.JAGF01000001_gene2807	9.817e-71	242.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4F0GE@85016|Cellulomonadaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158351_k127_1556409_1	710696.Intca_1895	3.129e-21	97.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4FE9F@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Class IV aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_1556409_2	350054.Mflv_3839	8.144e-12	71.0	2E4Q9@1|root,32ZIV@2|Bacteria,2II59@201174|Actinobacteria,23A1T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158351_k127_1556409_0	290399.Arth_2317	7.144e-178	566.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,1W7U2@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158351_k127_1569033_0	1416752.AYME01000006_gene1574	9.193e-75	256.0	COG3173@1|root,COG3173@2|Bacteria,2I4Z3@201174|Actinobacteria,4FKCJ@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158351_k127_1569033_1	1463920.JOGB01000039_gene916	3.877e-55	197.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158351_k127_1569364_1	1463853.JOHW01000009_gene462	4.629e-06	49.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1569364_0	1828.JOKB01000020_gene687	2.452e-138	448.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4FWN2@85025|Nocardiaceae	201174|Actinobacteria	E	GMC oxidoreductase	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158351_k127_1572533_2	58123.JOFJ01000006_gene91	3.223e-06	51.0	295AS@1|root,2ZSNY@2|Bacteria,2HDA6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1572533_0	1081644.IMCC13023_00390	2.273e-99	333.0	COG3329@1|root,COG3329@2|Bacteria,2I8DP@201174|Actinobacteria,4FRC1@85023|Microbacteriaceae	201174|Actinobacteria	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
SRR25158351_k127_1572533_1	1120934.KB894435_gene4487	5.467e-12	70.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4DYNW@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Haloacid Dehalogenase Superfamily Class (subfamily) IIA	yutF	GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158351_k127_1576426_3	471852.Tcur_3059	1.429e-12	68.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4EHII@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_1576426_4	1048339.KB913029_gene4617	1.237e-10	66.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1576426_0	1828.JOKB01000025_gene1935	3.267e-100	338.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4FU9N@85025|Nocardiaceae	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158351_k127_1576426_1	1048339.KB913029_gene4625	1.284e-47	174.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4ET4B@85013|Frankiales	201174|Actinobacteria	T	response regulator	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158351_k127_1576426_2	196162.Noca_3134	1.325e-19	90.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4DNEE@85009|Propionibacteriales	201174|Actinobacteria	C	cytochrome c oxidase subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158351_k127_1590493_1	298653.Franean1_5274	1.84e-98	326.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4ES45@85013|Frankiales	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158351_k127_1590493_2	1504319.GM45_5765	2.167e-96	319.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,3UWGF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158351_k127_1590493_0	1146883.BLASA_1533	2.752e-203	636.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4ERKD@85013|Frankiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158351_k127_1594536_2	1463821.JOGR01000003_gene1099	4.206e-15	75.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4EY7N@85014|Glycomycetales	201174|Actinobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158351_k127_1594536_1	1303692.SFUL_3003	3.997e-28	115.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding domain, excisionase family	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158351_k127_1594536_0	1048339.KB913029_gene2324	1.613e-79	274.0	COG0560@1|root,COG0560@2|Bacteria,2GJW9@201174|Actinobacteria,4ERWE@85013|Frankiales	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	serB1	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158351_k127_1594536_3	1122138.AQUZ01000014_gene7098	7.069e-12	66.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4DS21@85009|Propionibacteriales	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158351_k127_1598541_0	1123320.KB889677_gene2740	2.018e-124	404.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria	201174|Actinobacteria	C	malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158351_k127_1598541_1	1122622.ATWJ01000012_gene1117	3.068e-56	201.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4FGBG@85021|Intrasporangiaceae	201174|Actinobacteria	H	Molybdenum cofactor biosynthesis protein MoaC	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158351_k127_1598541_2	1380347.JNII01000010_gene2411	0.0003504	43.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4ESU1@85013|Frankiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
SRR25158351_k127_1603230_1	1032480.MLP_15000	2.07e-27	114.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4DRV5@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158351_k127_1603230_0	1172188.KB911821_gene1397	1.607e-95	321.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4FE45@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158351_k127_1603230_2	1120950.KB892769_gene5380	2.354e-11	65.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4DPDI@85009|Propionibacteriales	201174|Actinobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158351_k127_1607118_0	909613.UO65_3078	2.025e-157	508.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4DY5R@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158351_k127_1607118_2	1048339.KB913029_gene3873	1.311e-81	276.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4ESF8@85013|Frankiales	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158351_k127_1607118_1	479432.Sros_6760	1.338e-84	285.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4EGQI@85012|Streptosporangiales	201174|Actinobacteria	P	TrkA-N domain	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158351_k127_1607118_3	644284.Arch_0774	9.663e-16	79.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4D6CZ@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
SRR25158351_k127_1607167_2	288705.RSal33209_2044	4.003e-18	87.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,1W861@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
SRR25158351_k127_1607167_0	47839.CCAU010000016_gene4558	3.3e-139	450.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,232XI@1762|Mycobacteriaceae	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd2	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1122	6PGD,NAD_binding_2
SRR25158351_k127_1607167_1	1163407.UU7_15590	2.343e-33	132.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1X3XZ@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158351_k127_1608532_0	1246995.AFR_36600	1.008e-95	323.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DADB@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158351_k127_1608532_1	235985.BBPN01000031_gene2155	5.545e-66	230.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,2NEY0@228398|Streptacidiphilus	201174|Actinobacteria	M	D-ala D-ala ligase N-terminus	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158351_k127_1612254_1	1504319.GM45_2375	2.849e-117	380.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,3UWCZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158351_k127_1612254_0	65497.JODV01000007_gene373	8.39e-172	546.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4E03D@85010|Pseudonocardiales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158351_k127_1614036_1	1449353.JQMQ01000005_gene4619	1.968e-64	224.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,2NH4I@228398|Streptacidiphilus	201174|Actinobacteria	S	Zinc-binding dehydrogenase	adhA	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_1614036_0	1081644.IMCC13023_00890	1.925e-97	326.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4FMUC@85023|Microbacteriaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158351_k127_1614036_2	1121091.AUMP01000012_gene3360	6.255e-07	53.0	COG1028@1|root,COG1028@2|Bacteria,1TYDG@1239|Firmicutes,4HDFC@91061|Bacilli	91061|Bacilli	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_1620610_1	345341.KUTG_02992	1.705e-56	203.0	COG0778@1|root,COG0778@2|Bacteria,2HC1J@201174|Actinobacteria,4DZB0@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
SRR25158351_k127_1620610_0	591157.SSLG_02543	3.798e-60	211.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	pecS	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158351_k127_1628408_0	1169154.KB897783_gene4328	2.276e-103	349.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria	201174|Actinobacteria	S	modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158351_k127_1630142_0	1000565.METUNv1_01977	7.42e-145	464.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2VHAK@28216|Betaproteobacteria,2KUSP@206389|Rhodocyclales	206389|Rhodocyclales	H	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158351_k127_1633474_0	882083.SacmaDRAFT_5159	0.0	1405.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158351_k127_1633474_1	1157637.KB892119_gene150	8.102e-81	271.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158351_k127_1640064_0	1003195.SCAT_4685	2.924e-42	162.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria	201174|Actinobacteria	J	3-5 exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158351_k127_1640064_1	883069.HMPREF9238_00141	5.058e-39	152.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4D3SC@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158351_k127_1640780_0	1184607.AUCHE_05_02330	1.428e-49	193.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4F7F1@85018|Dermatophilaceae	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158351_k127_1640780_1	1048339.KB913029_gene4835	5.545e-34	139.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4ET14@85013|Frankiales	201174|Actinobacteria	L	helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158351_k127_1640780_2	1283283.ATXA01000004_gene4305	8.214e-07	53.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4ESRV@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein, DegV family COG1307	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158351_k127_1643808_1	529884.Rhola_00002540	3.906e-16	80.0	COG3545@1|root,COG3545@2|Bacteria,2IAFD@201174|Actinobacteria,4FQ1B@85023|Microbacteriaceae	201174|Actinobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
SRR25158351_k127_1643808_0	1121272.KB903253_gene6934	3.272e-51	191.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4DBDI@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158351_k127_1648342_2	1449346.JQMO01000003_gene3515	8.423e-42	156.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,2M1A8@2063|Kitasatospora	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158351_k127_1648342_3	953739.SVEN_5264	4.112e-20	91.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158351_k127_1648342_0	1048339.KB913029_gene3498	6.799e-87	293.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4ES99@85013|Frankiales	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158351_k127_1648342_1	208439.AJAP_09040	5.097e-57	203.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4DXDQ@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158351_k127_1650277_2	1504319.GM45_5755	6.745e-120	396.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,3UWAS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158351_k127_1650277_3	1172185.KB911515_gene2125	6.871e-78	267.0	COG1011@1|root,COG1011@2|Bacteria,2IBB1@201174|Actinobacteria,4G070@85025|Nocardiaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158351_k127_1650277_0	1120950.KB892765_gene5656	1.056e-270	859.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4DNEA@85009|Propionibacteriales	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158351_k127_1650277_6	665577.JH993790_gene3191	1.248e-05	50.0	2C5F8@1|root,346TI@2|Bacteria,2IQF7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1650277_4	1210046.B277_05683	1.409e-48	180.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4FF0H@85021|Intrasporangiaceae	201174|Actinobacteria	M	mechanosensitive ion channel protein MscS	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158351_k127_1650277_5	1121924.ATWH01000012_gene1091	3.744e-45	168.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4FNU8@85023|Microbacteriaceae	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158351_k127_1650277_1	928724.SacglDRAFT_01288	2.621e-127	416.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4DX7R@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158351_k127_1654381_1	67257.JODR01000001_gene830	3.16e-191	607.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158351_k127_1654381_2	479433.Caci_9035	1.363e-57	217.0	COG2270@1|root,COG2270@2|Bacteria,2GK5A@201174|Actinobacteria	201174|Actinobacteria	S	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1654381_0	479435.Kfla_7020	2.829e-201	630.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4DNQF@85009|Propionibacteriales	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158351_k127_1654381_3	44060.JODL01000037_gene3414	2.778e-57	205.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158351_k127_1662581_1	529884.Rhola_00012780	2.518e-39	151.0	COG2911@1|root,COG3210@1|root,COG3637@1|root,COG4412@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	2.7.11.1	ko:K07004,ko:K09955,ko:K12567,ko:K21449	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000,ko04131,ko04147,ko04812	1.B.40.2	-	-	DctA-YdbH,Laminin_G_3,OMP_b-brl
SRR25158351_k127_1662581_0	1449353.JQMQ01000005_gene2352	1.15e-78	265.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,2NH5M@228398|Streptacidiphilus	201174|Actinobacteria	HP	ThiF family	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158351_k127_1667502_1	351607.Acel_1297	5.558e-81	274.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4ESI4@85013|Frankiales	201174|Actinobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158351_k127_1667502_0	1504319.GM45_1345	2.535e-119	389.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158351_k127_1672734_0	1146883.BLASA_3661	6.463e-91	304.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4ERFR@85013|Frankiales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158351_k127_1677289_1	196162.Noca_4020	2.399e-58	206.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4DNYC@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158351_k127_1677289_0	2002.JOEQ01000009_gene6506	2.89e-153	495.0	COG3642@1|root,COG3642@2|Bacteria,2GIX0@201174|Actinobacteria,4EHC3@85012|Streptosporangiales	201174|Actinobacteria	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158351_k127_1677289_2	1203568.HMPREF1484_01410	1.768e-20	93.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4FBPP@85020|Dermabacteraceae	201174|Actinobacteria	P	TOBE domain	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158351_k127_1679722_1	44060.JODL01000019_gene4728	1.037e-47	179.0	COG0745@1|root,COG0745@2|Bacteria,2GP1I@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	vicR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_1679722_2	1032480.MLP_13540	2.022e-34	143.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4DQT5@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158351_k127_1679722_0	749414.SBI_04601	6.199e-255	794.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158351_k127_1691767_6	471874.PROSTU_02421	2.947e-17	84.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,3Z6XG@586|Providencia	1236|Gammaproteobacteria	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158351_k127_1691767_5	1155714.KB891995_gene3876	1.438e-29	126.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SRR25158351_k127_1691767_4	1246448.ANAZ01000007_gene2179	4.733e-72	248.0	COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,4EH75@85012|Streptosporangiales	201174|Actinobacteria	F	Domain of unknown function (DUF4916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4916
SRR25158351_k127_1691767_2	935839.JAGJ01000005_gene2600	1.429e-96	323.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4F3X4@85017|Promicromonosporaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158351_k127_1691767_1	1306174.JODP01000002_gene5902	3.617e-111	364.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208,ko:K11611	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1691767_3	235985.BBPN01000010_gene4453	4.845e-95	316.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,2NG0C@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158351_k127_1691767_0	66874.JOFS01000003_gene7215	1.726e-132	438.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria	201174|Actinobacteria	S	Modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158351_k127_1699840_2	529884.Rhola_00013130	1.124e-07	53.0	2B2E6@1|root,31UYR@2|Bacteria,2GUPA@201174|Actinobacteria,4FSK3@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1699840_1	1189619.pgond44_02653	2.064e-14	73.0	COG4338@1|root,COG4338@2|Bacteria,4NXFZ@976|Bacteroidetes,1I6JJ@117743|Flavobacteriia,4C4GJ@83612|Psychroflexus	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256
SRR25158351_k127_1699840_0	1504319.GM45_1470	2.343e-128	419.0	COG3046@1|root,COG3046@2|Bacteria,2GMF6@201174|Actinobacteria,3UX35@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	cry1	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
SRR25158351_k127_1711548_1	321955.AAGP01000001_gene3390	1.472e-20	93.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4F8TB@85019|Brevibacteriaceae	201174|Actinobacteria	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158351_k127_1711548_0	1156844.KB891820_gene132	5.993e-46	181.0	COG5650@1|root,COG5650@2|Bacteria,2GN1J@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158351_k127_1711548_2	1463903.JOIZ01000005_gene2765	1.412e-10	63.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	pimB	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_171708_1	446470.Snas_0896	1.181e-35	136.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4EXMT@85014|Glycomycetales	201174|Actinobacteria	J	tRNA synthetases class I (W and Y)	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158351_k127_171708_0	1122138.AQUZ01000084_gene8782	7.808e-138	447.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4DPDV@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158351_k127_1717516_1	1229781.C272_08957	5.022e-189	597.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4F9B8@85019|Brevibacteriaceae	201174|Actinobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158351_k127_1717516_4	1504319.GM45_0280	3.874e-88	297.0	COG1738@1|root,COG1738@2|Bacteria,2IFDB@201174|Actinobacteria,3UX0S@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158351_k127_1717516_3	1504319.GM45_4785	1.163e-132	436.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria,3UWG4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158351_k127_1717516_2	529884.Rhola_00005580	3.002e-137	444.0	COG2957@1|root,COG2957@2|Bacteria,2GM6J@201174|Actinobacteria,4FMVD@85023|Microbacteriaceae	201174|Actinobacteria	E	Porphyromonas-type peptidyl-arginine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SRR25158351_k127_1717516_6	1146883.BLASA_2576	8.245e-66	235.0	COG0697@1|root,COG0697@2|Bacteria,2GVE1@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1717516_0	1343740.M271_45170	1.235e-242	754.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158351_k127_1717516_10	529884.Rhola_00009750	6.131e-25	107.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158351_k127_1717516_8	1121272.KB903283_gene5261	2.135e-30	124.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4DA8R@85008|Micromonosporales	201174|Actinobacteria	K	TipAS antibiotic-recognition domain	tipA	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
SRR25158351_k127_1717516_7	1504319.GM45_4730	3.748e-46	172.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_1717516_5	529884.Rhola_00005540	8.676e-75	254.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria,4FNVB@85023|Microbacteriaceae	201174|Actinobacteria	O	Glutathione peroxidase	gpx	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158351_k127_1717516_9	1122622.ATWJ01000007_gene1829	2.777e-28	115.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4FES7@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158351_k127_173060_0	1081644.IMCC13023_13210	3.07e-184	580.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4FK8Q@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158351_k127_173060_4	529884.Rhola_00000270	3.31e-100	335.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4FKS9@85023|Microbacteriaceae	201174|Actinobacteria	E	Arginase family	-	-	3.5.3.11,3.5.3.8	ko:K01479,ko:K01480	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045,M00133	R01157,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158351_k127_173060_1	471852.Tcur_3397	3.231e-178	569.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EFMP@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_173060_2	1380356.JNIK01000015_gene2347	1.073e-136	441.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158351_k127_173060_3	1121877.JQKF01000001_gene1331	1.726e-116	385.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CNVA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158351_k127_173060_5	1206741.BAFX01000108_gene1127	8.978e-50	184.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4FUZK@85025|Nocardiaceae	201174|Actinobacteria	EG	EamA-like transporter family	cyeA	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1741140_0	1504319.GM45_5885	0.0	1091.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,3UWBT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158351_k127_1741140_1	284031.JNXD01000001_gene5432	1.242e-18	88.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	cyeA	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_1742865_1	1996.JOFO01000002_gene5479	2.187e-36	139.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4EHTF@85012|Streptosporangiales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158351_k127_1742865_2	40571.JOEA01000044_gene5562	4.427e-22	103.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4E2J0@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall-associated hydrolase, invasion-associated protein	-	GO:0005575,GO:0005576	-	ko:K21471,ko:K21473	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158351_k127_1742865_0	469371.Tbis_1165	3.722e-272	845.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4DZ7I@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158351_k127_1743271_0	471857.Svir_36740	7.702e-109	363.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158351_k127_1751178_1	1894.JOER01000030_gene483	1.613e-118	389.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158351_k127_1751178_2	1123322.KB904635_gene2477	4.24e-56	200.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158351_k127_1751178_0	351607.Acel_1818	1.387e-148	481.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4ERJN@85013|Frankiales	201174|Actinobacteria	P	CBS domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR25158351_k127_1761243_0	1463841.JOIR01000060_gene7129	2.504e-84	284.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158351_k127_1761243_1	1048339.KB913029_gene522	1.775e-06	51.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4EW1V@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	pecS	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158351_k127_1764801_1	529884.Rhola_00012660	5.471e-57	205.0	COG2197@1|root,COG2197@2|Bacteria,2HSNY@201174|Actinobacteria,4FPMD@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_1764801_2	1504319.GM45_3445	2.715e-52	193.0	COG2141@1|root,COG2141@2|Bacteria,2GPKW@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1764801_0	1394178.AWOO02000087_gene944	2.944e-174	552.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4EID1@85012|Streptosporangiales	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158351_k127_1764801_3	479433.Caci_1533	5.563e-18	83.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158351_k127_1770570_0	1121366.KB892441_gene2303	5.027e-96	321.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,22JR0@1653|Corynebacteriaceae	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158351_k127_1770570_1	935839.JAGJ01000011_gene449	7.645e-36	139.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4F495@85017|Promicromonosporaceae	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
SRR25158351_k127_1770636_0	1449355.JQNR01000005_gene4645	1.195e-41	158.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria	201174|Actinobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158351_k127_1770636_2	288705.RSal33209_1090	3.918e-18	88.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,1WA4Z@1268|Micrococcaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158351_k127_1770636_1	479432.Sros_1835	1.343e-38	146.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4EJHJ@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158351_k127_1779873_2	1306174.JODP01000001_gene5346	7.205e-51	194.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	cvpA	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158351_k127_1779873_0	1504319.GM45_3860	7.14e-321	992.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,3UWEN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158351_k127_1779873_1	529884.Rhola_00013500	1.079e-121	402.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4FM51@85023|Microbacteriaceae	201174|Actinobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158351_k127_1779873_5	1414719.CBYN010000090_gene1208	0.000182	49.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,22NA1@1653|Corynebacteriaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158351_k127_1779873_6	1210046.B277_04879	0.0007303	48.0	COG3177@1|root,COG3177@2|Bacteria,2GIT8@201174|Actinobacteria,4FFUU@85021|Intrasporangiaceae	201174|Actinobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158351_k127_1779873_4	1283287.KB822575_gene560	5.019e-14	76.0	COG3177@1|root,COG3177@2|Bacteria,2GIT8@201174|Actinobacteria,4DNV2@85009|Propionibacteriales	201174|Actinobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158351_k127_1779873_3	134676.ACPL_478	1.121e-15	84.0	COG0489@1|root,COG0489@2|Bacteria,2I2TA@201174|Actinobacteria,4DA8N@85008|Micromonosporales	201174|Actinobacteria	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158351_k127_1784708_1	1463903.JOIZ01000018_gene603	2.303e-13	75.0	COG0204@1|root,COG0204@2|Bacteria,2IBCT@201174|Actinobacteria	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158351_k127_1784708_0	266940.Krad_1166	1.014e-149	482.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158351_k127_1791310_4	35754.JNYJ01000038_gene4997	8.041e-66	238.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DACF@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158351_k127_1791310_2	1155718.KB891901_gene1694	5.748e-104	346.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158351_k127_1791310_3	33876.JNXY01000025_gene5487	8.939e-70	246.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4D99B@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158351_k127_1791310_1	1150864.MILUP08_46700	1.203e-114	374.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4D9W0@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158351_k127_1791310_0	1108045.GORHZ_058_00020	1.657e-117	384.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4GBTZ@85026|Gordoniaceae	201174|Actinobacteria	J	tRNA synthetases class II (D, K and N)	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_1800255_0	512565.AMIS_73640	5.224e-118	389.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4DB04@85008|Micromonosporales	201174|Actinobacteria	E	Aminotransferase	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158351_k127_1800255_2	216594.MMAR_4274	9.896e-55	193.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,239CP@1762|Mycobacteriaceae	201174|Actinobacteria	C	ferredoxin	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
SRR25158351_k127_1800255_1	2045.KR76_20790	4.108e-71	246.0	COG2120@1|root,COG2120@2|Bacteria,2GKUM@201174|Actinobacteria,4DN6S@85009|Propionibacteriales	201174|Actinobacteria	S	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway	mshB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	3.5.1.103	ko:K15525	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158351_k127_1802926_10	561175.KB894098_gene5402	2.544e-07	57.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4EIDJ@85012|Streptosporangiales	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158351_k127_1802926_11	367299.JOEE01000004_gene1355	5.783e-07	57.0	2E5Y6@1|root,330MX@2|Bacteria,2IT4J@201174|Actinobacteria,4FGEE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1802926_2	1463887.KL590001_gene5546	2.021e-121	396.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria	201174|Actinobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158351_k127_1802926_6	263358.VAB18032_26841	1.181e-51	187.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4DD2W@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158351_k127_1802926_5	391037.Sare_3193	1.04e-85	293.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4DBTB@85008|Micromonosporales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_1802926_7	1048339.KB913029_gene1368	6.187e-23	108.0	COG2931@1|root,COG3064@1|root,COG2931@2|Bacteria,COG3064@2|Bacteria,2IPMP@201174|Actinobacteria,4EWGV@85013|Frankiales	201174|Actinobacteria	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1802926_9	1304876.AZVC01000018_gene2414	9.543e-17	85.0	2E49S@1|root,32Z5G@2|Bacteria,2IHN1@201174|Actinobacteria,1W9RP@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR25158351_k127_1802926_1	1504319.GM45_1065	1.14e-132	434.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,3UWHJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158351_k127_1802926_0	1449347.JQLN01000007_gene1597	3.394e-171	549.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,2M0VW@2063|Kitasatospora	201174|Actinobacteria	E	Pfam FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158351_k127_1802926_4	1306174.JODP01000016_gene7162	4.862e-93	312.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158351_k127_1802926_3	1306174.JODP01000016_gene7161	6.532e-104	346.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158351_k127_1802926_8	436229.JOEH01000010_gene5168	4.423e-22	99.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,2NG9M@228398|Streptacidiphilus	201174|Actinobacteria	E	TOBE domain	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158351_k127_1803421_1	1122611.KB903943_gene1536	1.359e-54	196.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4EG3M@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158351_k127_1803421_2	1123320.KB889585_gene1747	1.317e-53	195.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Thymidylate_kin
SRR25158351_k127_1803421_0	1120950.KB892762_gene5449	6.468e-136	443.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4DN7K@85009|Propionibacteriales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158351_k127_1810650_2	479433.Caci_5238	1.216e-09	68.0	COG0477@1|root,COG2814@2|Bacteria,2GMCR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_1810650_0	529884.Rhola_00012670	1.254e-146	476.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4FNCM@85023|Microbacteriaceae	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRR25158351_k127_1810650_1	1449080.JQMV01000003_gene1178	1.342e-35	143.0	COG1268@1|root,COG1268@2|Bacteria,1WJ9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158351_k127_1810650_3	1380391.JIAS01000018_gene917	1.289e-06	52.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,2JQUK@204441|Rhodospirillales	204441|Rhodospirillales	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158351_k127_181084_1	1193181.BN10_810009	6.398e-49	182.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4FGFA@85021|Intrasporangiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_181084_2	471853.Bcav_1965	2.596e-47	176.0	2AIF4@1|root,318WM@2|Bacteria,2GK8R@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
SRR25158351_k127_181084_0	1043205.AFYF01000026_gene311	1.302e-72	249.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4FEWV@85021|Intrasporangiaceae	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158351_k127_1819533_0	1095767.CAHD01000224_gene2103	1.871e-163	519.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4F0MZ@85016|Cellulomonadaceae	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158351_k127_1820638_0	1283283.ATXA01000001_gene968	3.359e-78	267.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria,4ETX3@85013|Frankiales	201174|Actinobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158351_k127_1820638_1	593907.Celgi_2877	1.083e-21	96.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4F0S4@85016|Cellulomonadaceae	201174|Actinobacteria	F	PFAM Xanthine uracil vitamin C permease	rutG	-	-	ko:K02824,ko:K03458	-	-	-	-	ko00000,ko02000	2.A.40,2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
SRR25158351_k127_1822727_6	290340.AAur_2487	2.904e-27	111.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,1W7JQ@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158351_k127_1822727_0	1210045.ALNP01000023_gene2869	2.391e-254	790.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158351_k127_1822727_2	1386089.N865_13780	9.4e-94	310.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4FE44@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2987c	Aconitase_C
SRR25158351_k127_1822727_5	1122609.AUGT01000005_gene1589	3.086e-30	123.0	COG0776@1|root,COG0776@2|Bacteria,2IKQR@201174|Actinobacteria,4DSEF@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the bacterial histone-like protein family	hup	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158351_k127_1822727_3	1123320.KB889676_gene2895	1.646e-75	261.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158351_k127_1822727_1	1003195.SCAT_4393	5.762e-121	397.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158351_k127_1822727_4	2045.KR76_18415	1.092e-56	202.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4DMZ2@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158351_k127_182338_0	1193181.BN10_360007	4.742e-55	201.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4FFYP@85021|Intrasporangiaceae	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158351_k127_182338_1	68570.DC74_2648	5.248e-35	136.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria	201174|Actinobacteria	G	Ribokinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1830024_2	288705.RSal33209_1578	0.0003443	44.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,1W82C@1268|Micrococcaceae	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158351_k127_1830024_0	1003195.SCAT_1274	1.597e-90	304.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158351_k127_1830024_1	1169161.KB897723_gene4746	3.082e-64	221.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria	201174|Actinobacteria	C	cytochrome c oxidase, subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158351_k127_1832326_1	290340.AAur_0349	1.276e-31	130.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,1W7SN@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158351_k127_1832326_3	1449346.JQMO01000003_gene2766	4.98e-26	112.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,2M533@2063|Kitasatospora	201174|Actinobacteria	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158351_k127_1832326_2	405948.SACE_2275	3.413e-26	110.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,2GJU4@201174|Actinobacteria,4E0S5@85010|Pseudonocardiales	201174|Actinobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158351_k127_1832326_0	593907.Celgi_0896	3.719e-57	203.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,2GJU4@201174|Actinobacteria	201174|Actinobacteria	GT	Phosphotransferase System	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158351_k127_1832620_3	33876.JNXY01000013_gene4095	3.522e-05	46.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4DB8X@85008|Micromonosporales	201174|Actinobacteria	Q	phytoene	crtI2	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158351_k127_1832620_1	351607.Acel_0992	3.391e-33	134.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria,4ET17@85013|Frankiales	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158351_k127_1832620_0	436229.JOEH01000057_gene5658	3.977e-207	653.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,2NFQ7@228398|Streptacidiphilus	201174|Actinobacteria	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_1832620_2	457429.ABJI02000204_gene5682	2.484e-15	78.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.9	ko:K00128,ko:K00131	ko00010,ko00030,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00135,M00308,M00633	R00264,R00631,R00710,R00904,R01058,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_1839685_15	44060.JODL01000029_gene827	1.218e-38	149.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158351_k127_1839685_16	1089549.AZUQ01000001_gene890	2.703e-33	132.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,4EYVJ@85014|Glycomycetales	201174|Actinobacteria	I	4'-phosphopantetheinyl transferase superfamily	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158351_k127_1839685_0	953739.SVEN_4418	5.461e-282	877.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158351_k127_1839685_3	1123320.KB889574_gene5538	6.249e-165	530.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_1839685_10	1151118.KB895783_gene3781	7.956e-64	222.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,1W8XZ@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158351_k127_1839685_9	1074488.AGBX01000008_gene2590	3.227e-69	237.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4FB9U@85020|Dermabacteraceae	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158351_k127_1839685_7	935866.JAER01000056_gene288	3.352e-70	247.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DPSE@85009|Propionibacteriales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158351_k127_1839685_13	1123322.KB904651_gene437	6.34e-59	209.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria	201174|Actinobacteria	J	ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158351_k127_1839685_2	1089455.MOPEL_098_00520	1.257e-165	527.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4F6GR@85018|Dermatophilaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158351_k127_1839685_4	1123320.KB889574_gene5545	2.219e-110	359.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158351_k127_1839685_8	287986.DV20_18980	2.939e-69	237.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4E2JI@85010|Pseudonocardiales	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158351_k127_1839685_12	883077.HMPREF9241_01269	4.979e-62	214.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4D5U8@85005|Actinomycetales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158351_k127_1839685_17	762948.HMPREF0733_10277	1.651e-16	78.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,1WA8T@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158351_k127_1839685_14	269800.Tfu_2622	2.587e-39	147.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4EK2Q@85012|Streptosporangiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158351_k127_1839685_5	196162.Noca_3883	2.566e-95	319.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4DNQ9@85009|Propionibacteriales	201174|Actinobacteria	J	Methionine aminopeptidase	mapA	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158351_k127_1839685_6	1283287.KB822575_gene134	1.811e-74	254.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4DP2T@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158351_k127_1839685_1	1504319.GM45_2550	1.584e-192	608.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,3UWEW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158351_k127_1839685_11	1298863.AUEP01000004_gene2153	5.683e-63	218.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4DQND@85009|Propionibacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158351_k127_1839685_18	1122998.AUHZ01000002_gene2142	2.828e-14	72.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4DSCE@85009|Propionibacteriales	201174|Actinobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158351_k127_1847578_1	269800.Tfu_0647	5.323e-41	158.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4EJ83@85012|Streptosporangiales	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158351_k127_1847578_0	2074.JNYD01000013_gene6849	5.773e-64	222.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4E33S@85010|Pseudonocardiales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158351_k127_1847578_2	408672.NBCG_02061	2.469e-32	128.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4DQUU@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158351_k127_1849988_2	1454010.JEOE01000002_gene511	3.19e-43	167.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4F10Q@85016|Cellulomonadaceae	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158351_k127_1849988_3	2002.JOEQ01000001_gene4654	6.096e-11	69.0	COG0776@1|root,COG0776@2|Bacteria,2IR95@201174|Actinobacteria,4EK0D@85012|Streptosporangiales	201174|Actinobacteria	L	regulation of translation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1849988_1	1504319.GM45_5550	4.123e-45	174.0	COG3757@1|root,COG3757@2|Bacteria	2|Bacteria	M	lysozyme activity	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,MORN
SRR25158351_k127_1849988_0	1081644.IMCC13023_10810	4.393e-88	296.0	COG0813@1|root,COG0813@2|Bacteria,2GNT6@201174|Actinobacteria,4FQJG@85023|Microbacteriaceae	201174|Actinobacteria	F	Phosphorylase superfamily	deoD	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158351_k127_1849988_4	935839.JAGJ01000007_gene3145	1e-10	70.0	2BMTT@1|root,32GDB@2|Bacteria,2I0S3@201174|Actinobacteria,4F5SC@85017|Promicromonosporaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
SRR25158351_k127_1849988_5	101510.RHA1_ro05216	4.18e-05	49.0	COG2356@1|root,COG3064@1|root,COG2356@2|Bacteria,COG3064@2|Bacteria,2GJ38@201174|Actinobacteria,4G9HT@85025|Nocardiaceae	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,Excalibur
SRR25158351_k127_1862236_1	405948.SACE_2041	6.501e-53	187.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4E0SI@85010|Pseudonocardiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_1862236_0	1121372.AULK01000001_gene2083	5.275e-162	520.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4FKCI@85023|Microbacteriaceae	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158351_k127_1862954_0	253839.SSNG_05244	7.446e-255	792.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158351_k127_1862954_1	981369.JQMJ01000004_gene5556	1.579e-142	462.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,2NGPG@228398|Streptacidiphilus	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158351_k127_1865864_1	1120950.KB892708_gene4284	8.068e-51	182.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DP1N@85009|Propionibacteriales	201174|Actinobacteria	J	Histidine--tRNA ligase	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158351_k127_1865864_0	935866.JAER01000015_gene1674	1.289e-68	240.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4DNMS@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158351_k127_1866342_1	717606.PaecuDRAFT_0077	5.552e-17	83.0	COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,26YHQ@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158351_k127_1866342_0	1121372.AULK01000010_gene512	2.35e-32	132.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria,4FN5W@85023|Microbacteriaceae	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158351_k127_1871144_1	1449976.KALB_7224	8.623e-29	127.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DX9Q@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA RNA helicase, superfamily II	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158351_k127_1871144_0	298655.KI912266_gene1932	4.709e-56	215.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4ERYH@85013|Frankiales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158351_k127_1871144_2	326427.Cagg_2469	1.378e-18	89.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_1871302_0	1121017.AUFG01000009_gene1541	2.425e-54	198.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4FFVS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_1871302_1	1894.JOER01000041_gene1457	3.093e-31	126.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158351_k127_1871735_0	298655.KI912266_gene105	3.975e-139	452.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ERKI@85013|Frankiales	201174|Actinobacteria	U	type II secretion system protein E	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158351_k127_1871735_2	1123065.ATWL01000020_gene3546	7.318e-51	188.0	COG2064@1|root,COG2064@2|Bacteria,2GKMW@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158351_k127_1871735_3	1304865.JAGF01000001_gene3984	7.4e-35	145.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4F0GG@85016|Cellulomonadaceae	201174|Actinobacteria	NU	PFAM Type II secretion system F domain	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158351_k127_1871735_4	710696.Intca_1289	2.79e-12	70.0	2EG89@1|root,33A03@2|Bacteria,2GX3U@201174|Actinobacteria,4FHPM@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1871735_6	1095767.CAHD01000238_gene1796	2.748e-05	51.0	2E9Y4@1|root,3343S@2|Bacteria,2GR3H@201174|Actinobacteria,4F1KE@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1871735_5	710696.Intca_1292	8.384e-06	54.0	2EBSZ@1|root,335SP@2|Bacteria,2IS2J@201174|Actinobacteria,4FH9T@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158351_k127_1871735_1	1120950.KB892764_gene5648	6.94e-138	445.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z5@201174|Actinobacteria,4DWIV@85009|Propionibacteriales	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_1878169_6	351607.Acel_2026	2.939e-82	282.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4ESJ5@85013|Frankiales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158351_k127_1878169_7	1121946.AUAX01000019_gene7777	1.748e-65	230.0	COG3340@1|root,COG3340@2|Bacteria,2ISWE@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158351_k127_1878169_5	351607.Acel_2052	2.881e-82	287.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2I98G@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1878169_0	1123322.KB904703_gene60	9.052e-282	883.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158351_k127_1878169_8	478801.Ksed_03520	5.981e-58	212.0	COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,1ZVUQ@145357|Dermacoccaceae	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158351_k127_1878169_2	1210045.ALNP01000001_gene3251	8.555e-114	373.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158351_k127_1878169_3	1120959.ATXF01000008_gene589	6.46e-109	359.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4FR63@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158351_k127_1878169_1	1452536.JARE01000045_gene2219	3.462e-120	392.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158351_k127_1878169_4	1122138.AQUZ01000094_gene5499	9.298e-98	324.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158351_k127_1881338_1	1528106.JRJE01000028_gene393	5.18e-108	370.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria,1MX0Y@1224|Proteobacteria,2TRAZ@28211|Alphaproteobacteria,2JRF7@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
SRR25158351_k127_1881338_0	1504319.GM45_0405	1.949e-147	478.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,3UWP0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
SRR25158351_k127_1881338_2	1385519.N801_04890	2.032e-71	246.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4FEWQ@85021|Intrasporangiaceae	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158351_k127_1883935_0	1193181.BN10_1080028	1.986e-122	398.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FFUG@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158351_k127_1883935_1	443906.CMM_1725	3.617e-09	63.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4FKFS@85023|Microbacteriaceae	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158351_k127_1884239_4	211114.JOEF01000018_gene6249	1.147e-141	457.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DXR6@85010|Pseudonocardiales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158351_k127_1884239_0	351607.Acel_1124	3.045e-265	822.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4ES6Y@85013|Frankiales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158351_k127_1884239_7	66869.JNXG01000013_gene6712	3.074e-90	306.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4199E@629295|Streptomyces griseus group	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158351_k127_1884239_9	1171373.PACID_22690	8.235e-38	150.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4DQAQ@85009|Propionibacteriales	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158351_k127_1884239_8	269800.Tfu_2013	1.079e-49	178.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria,4EJFH@85012|Streptosporangiales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158351_k127_1884239_11	585531.HMPREF0063_10829	3.048e-25	106.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4DS3V@85009|Propionibacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158351_k127_1884239_5	1449353.JQMQ01000005_gene1631	7.547e-119	386.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,2NH0X@228398|Streptacidiphilus	201174|Actinobacteria	G	Triosephosphate isomerase	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158351_k127_1884239_3	1043493.BBLU01000001_gene1010	2.797e-154	496.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158351_k127_1884239_1	219305.MCAG_01101	1.266e-170	540.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D98B@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158351_k127_1884239_2	1048339.KB913029_gene4392	6.778e-167	528.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4ERBX@85013|Frankiales	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158351_k127_1884239_6	469371.Tbis_1995	6.355e-99	331.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4DZS2@85010|Pseudonocardiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158351_k127_1884239_10	58344.JOEL01000004_gene6928	1.653e-33	130.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158351_k127_1887389_1	2002.JOEQ01000030_gene2158	2.671e-76	261.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria,4EG93@85012|Streptosporangiales	201174|Actinobacteria	P	Periplasmic binding protein	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158351_k127_1887389_0	1121946.AUAX01000006_gene3574	8.995e-100	336.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4D9B0@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158351_k127_189557_0	762948.HMPREF0733_10457	2.626e-139	447.0	COG1054@1|root,COG1054@2|Bacteria,2GMMP@201174|Actinobacteria,1W8JF@1268|Micrococcaceae	201174|Actinobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
SRR25158351_k127_189557_1	1123013.AUIC01000003_gene773	5.319e-12	68.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FMKM@85023|Microbacteriaceae	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158351_k127_1896828_0	446468.Ndas_3623	3.924e-201	631.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4EID0@85012|Streptosporangiales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158351_k127_1896828_2	457425.XNR_1161	8.209e-76	263.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158351_k127_1896828_1	1306174.JODP01000016_gene7173	5.942e-100	329.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158351_k127_1898961_9	1206101.AZXC01000006_gene4079	7.629e-116	374.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158351_k127_1898961_12	196162.Noca_0524	3.709e-79	270.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4DN2R@85009|Propionibacteriales	201174|Actinobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158351_k127_1898961_3	1504319.GM45_4145	4.383e-218	683.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,3UWD5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158351_k127_1898961_1	710686.Mycsm_01539	4.618e-252	797.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,232CD@1762|Mycobacteriaceae	201174|Actinobacteria	C	NADH-quinone oxidoreductase	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158351_k127_1898961_6	1504319.GM45_4155	4.08e-174	556.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,3UW85@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
SRR25158351_k127_1898961_11	1504319.GM45_4160	9.79e-89	295.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,3UWSS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR25158351_k127_1898961_13	700508.D174_09455	8.016e-67	235.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,233A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158351_k127_1898961_14	1504319.GM45_4170	1.343e-38	146.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,3UWX9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158351_k127_1898961_2	1449069.JMLO01000014_gene4415	3.346e-251	788.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4FWHS@85025|Nocardiaceae	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158351_k127_1898961_7	1394178.AWOO02000038_gene9136	1.117e-172	558.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4EH1X@85012|Streptosporangiales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_1898961_5	1120950.KB892779_gene958	2.789e-174	561.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4DNIM@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158351_k127_1898961_8	1343740.M271_22030	1.264e-117	386.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158351_k127_1898961_10	66897.DJ64_08095	5.096e-94	317.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria	201174|Actinobacteria	S	RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
SRR25158351_k127_1898961_4	471852.Tcur_4392	2.349e-174	553.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4EH97@85012|Streptosporangiales	201174|Actinobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158351_k127_1898961_0	1123320.KB889574_gene5632	4.109e-306	947.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158351_k127_1898961_15	40571.JOEA01000013_gene1235	3.31e-20	94.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria,4E3JM@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158351_k127_1900152_0	1223523.H340_12987	5.103e-194	616.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158351_k127_1914659_1	1033730.CAHG01000015_gene694	4.579e-106	351.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4DP8J@85009|Propionibacteriales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158351_k127_1914659_0	1123251.ATWM01000003_gene1134	1.276e-110	361.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4FG22@85021|Intrasporangiaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158351_k127_1914659_2	446468.Ndas_0386	8.386e-68	235.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4EH8W@85012|Streptosporangiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158351_k127_1914659_4	1035839.AFNK01000085_gene486	3.82e-07	52.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1914659_3	1122609.AUGT01000005_gene1762	5.509e-60	209.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DN9V@85009|Propionibacteriales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158351_k127_1922078_1	1278078.G419_02730	0.0001907	45.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4FUAR@85025|Nocardiaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158351_k127_1922078_0	469371.Tbis_1735	3.749e-128	419.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4E0X1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158351_k127_1931947_0	1394178.AWOO02000073_gene2300	6.354e-137	443.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4EFNT@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158351_k127_1940760_1	298654.FraEuI1c_3753	2.006e-177	567.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4ERN8@85013|Frankiales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158351_k127_1940760_3	861360.AARI_16380	3.341e-08	56.0	2E9C2@1|root,333JS@2|Bacteria,2HTC5@201174|Actinobacteria,1WA9J@1268|Micrococcaceae	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158351_k127_1940760_0	266940.Krad_1875	2.14e-206	650.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158351_k127_1940760_2	1504319.GM45_5510	3.684e-28	120.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,3UWVE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158351_k127_1950811_0	1169154.KB897784_gene4300	3.014e-65	229.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria	201174|Actinobacteria	A	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158351_k127_1950811_1	205914.HS_0557	1.586e-20	98.0	2E0GI@1|root,32W2H@2|Bacteria,1N29Q@1224|Proteobacteria,1SAIH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1950811_2	526225.Gobs_3018	1.687e-17	85.0	COG0629@1|root,COG0629@2|Bacteria,2GRPQ@201174|Actinobacteria	201174|Actinobacteria	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_195200_1	1122247.C731_3144	6.982e-45	170.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,233VA@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM inositol monophosphatase	cysQ_1	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158351_k127_195200_0	935866.JAER01000005_gene93	1.759e-69	240.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4DPFB@85009|Propionibacteriales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158351_k127_195200_2	1120960.ATXG01000015_gene1548	8.817e-25	109.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4FNG9@85023|Microbacteriaceae	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158351_k127_195200_3	1713.JOFV01000023_gene1334	1.742e-23	100.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4F0MN@85016|Cellulomonadaceae	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158351_k127_1968040_1	1504319.GM45_4880	8.322e-64	222.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,3UWU9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Carbonic anhydrase	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158351_k127_1968040_4	1048834.TC41_1513	3.316e-13	71.0	COG1942@1|root,COG1942@2|Bacteria	2|Bacteria	S	isomerase activity	dmpI	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2,Tautomerase
SRR25158351_k127_1968040_0	479433.Caci_1763	4.294e-298	930.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158351_k127_1968040_3	446468.Ndas_3308	2.054e-16	81.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,4EKEQ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1968040_2	471853.Bcav_3246	3.324e-31	127.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158351_k127_1974275_0	928724.SacglDRAFT_03314	1.705e-170	557.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4E0JP@85010|Pseudonocardiales	201174|Actinobacteria	KL	helicase	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158351_k127_1974275_1	1385518.N798_15925	4.548e-60	211.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4FESB@85021|Intrasporangiaceae	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158351_k127_1977896_1	1089455.MOPEL_074_00230	3.471e-62	216.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4F662@85018|Dermatophilaceae	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158351_k127_1977896_0	479433.Caci_8083	3.393e-77	264.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158351_k127_1977896_2	1210045.ALNP01000001_gene3381	2.698e-44	167.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158351_k127_1987594_1	1123023.JIAI01000030_gene4403	3.843e-62	220.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DYBT@85010|Pseudonocardiales	201174|Actinobacteria	L	Tyrosine recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158351_k127_1987594_0	1348663.KCH_57720	3.711e-70	239.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,2M1MV@2063|Kitasatospora	201174|Actinobacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158351_k127_1988375_0	1156844.KB891849_gene3343	1.169e-144	475.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158351_k127_1988375_1	1050202.KB913024_gene1185	3.303e-10	64.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,408RU@622450|Actinopolysporales	201174|Actinobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158351_k127_1992779_6	743718.Isova_2305	2.238e-11	65.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4F4WN@85017|Promicromonosporaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158351_k127_1992779_2	1504319.GM45_6075	5.242e-82	280.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,3UWN7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158351_k127_1992779_4	1504319.GM45_6070	2.937e-18	87.0	2972E@1|root,2ZUAS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1992779_3	1077144.AGFF01000023_gene1102	1.204e-18	91.0	2BJAR@1|root,32DKN@2|Bacteria,2IT37@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_1992779_1	1504319.GM45_6060	1.506e-123	405.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,3UWGE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158351_k127_1992779_0	1146883.BLASA_3927	3.962e-207	650.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4ERC5@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158351_k127_1992779_5	298654.FraEuI1c_0930	2.146e-12	70.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4ESEK@85013|Frankiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158351_k127_199540_0	1463934.JOCF01000028_gene7120	4.542e-241	752.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158351_k127_199540_1	1122138.AQUZ01000019_gene8169	4.492e-121	399.0	COG1679@1|root,COG1679@2|Bacteria,2GMWV@201174|Actinobacteria,4DT5W@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
SRR25158351_k127_2008113_0	234621.RER_27240	1.016e-116	379.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4FWEQ@85025|Nocardiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158351_k127_2008113_2	1449069.JMLO01000014_gene4407	1.012e-103	342.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4FUNS@85025|Nocardiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158351_k127_2008113_3	1048339.KB913029_gene2577	1.691e-98	323.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4ERM4@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158351_k127_2008113_4	1003195.SCAT_3484	1.065e-56	199.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158351_k127_2008113_1	479433.Caci_8055	6.274e-106	348.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158351_k127_2008113_5	68170.KL590469_gene1740	1.398e-33	137.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DY9A@85010|Pseudonocardiales	201174|Actinobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158351_k127_2011061_0	1328313.DS2_02278	1.161e-52	199.0	COG0845@1|root,COG0845@2|Bacteria,1R50D@1224|Proteobacteria,1RRYM@1236|Gammaproteobacteria,465YX@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158351_k127_2018308_0	1476876.JOJO01000003_gene5745	1.526e-128	414.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158351_k127_2018308_1	196162.Noca_2431	9.604e-94	309.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4DNSQ@85009|Propionibacteriales	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158351_k127_2018490_1	1236902.ANAS01000009_gene2648	9.505e-19	92.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4EHWU@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158351_k127_2018490_0	105422.BBPM01000023_gene3550	2.484e-64	229.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,2NF40@228398|Streptacidiphilus	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158351_k127_2026167_2	1122130.AUHN01000004_gene1014	1.251e-41	157.0	COG0785@1|root,COG0785@2|Bacteria,2IMP9@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_2026167_4	1089544.KB912942_gene1708	2.405e-22	99.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,4E5PE@85010|Pseudonocardiales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
SRR25158351_k127_2026167_0	1121017.AUFG01000007_gene1332	1.105e-198	633.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,2H7WY@201174|Actinobacteria,4FFX6@85021|Intrasporangiaceae	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158351_k127_2026167_1	1283299.AUKG01000004_gene1186	1.173e-54	204.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CPRG@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2
SRR25158351_k127_2026167_3	649639.Bcell_1225	3.799e-37	144.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,1ZGCX@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158351_k127_2032058_1	529884.Rhola_00002540	4.168e-31	126.0	COG3545@1|root,COG3545@2|Bacteria,2IAFD@201174|Actinobacteria,4FQ1B@85023|Microbacteriaceae	201174|Actinobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
SRR25158351_k127_2032058_2	1184609.KILIM_013_00090	2.207e-21	96.0	2CDZD@1|root,32RYT@2|Bacteria	2|Bacteria	S	Virulence factor	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
SRR25158351_k127_2032058_0	1298863.AUEP01000004_gene2227	7.025e-104	345.0	COG0646@1|root,COG0646@2|Bacteria,2IEWZ@201174|Actinobacteria	201174|Actinobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
SRR25158351_k127_2035905_0	105420.BBPO01000046_gene1031	4.335e-227	717.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,2NKTH@228398|Streptacidiphilus	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158351_k127_2036145_1	1122609.AUGT01000012_gene4312	7.748e-75	265.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4DNHR@85009|Propionibacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
SRR25158351_k127_2036145_0	479435.Kfla_2885	1.605e-168	542.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4DNTV@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_2036145_2	1123321.KB905815_gene3291	5.354e-64	221.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158351_k127_2042057_2	196162.Noca_1115	9.045e-73	250.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_2042057_0	196162.Noca_0642	0.0	1126.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4DPE4@85009|Propionibacteriales	201174|Actinobacteria	E	glycine cleavage T protein (aminomethyl transferase)	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158351_k127_2042057_1	110319.CF8_0371	1.074e-82	293.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria	201174|Actinobacteria	QT	Regulator of polyketide synthase expression	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158351_k127_2042057_3	1501269.EW15_0082	1.465e-24	115.0	COG2931@1|root,COG2931@2|Bacteria,1GMX7@1117|Cyanobacteria,1MNBJ@1212|Prochloraceae	1117|Cyanobacteria	Q	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214
SRR25158351_k127_2044554_0	1223523.H340_21046	4.959e-178	565.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria	201174|Actinobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158351_k127_2044554_1	529884.Rhola_00000290	1.995e-83	281.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4FKFI@85023|Microbacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158351_k127_2054739_3	1348662.CARG_05670	1.265e-06	51.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,22JY6@1653|Corynebacteriaceae	201174|Actinobacteria	K	Transcriptional regulators of sugar metabolism	sugR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158351_k127_2054739_0	1081644.IMCC13023_04850	2.644e-167	532.0	COG2213@1|root,COG2213@2|Bacteria,2GMYR@201174|Actinobacteria,4FKI3@85023|Microbacteriaceae	201174|Actinobacteria	G	Phosphotransferase system, EIIC	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158351_k127_2054739_1	1081644.IMCC13023_04860	1.618e-36	140.0	COG2213@1|root,COG2213@2|Bacteria,2IRUU@201174|Actinobacteria	201174|Actinobacteria	G	Phosphotransferase System	-	-	2.7.1.197	ko:K02799	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_IIB
SRR25158351_k127_2054739_2	1081644.IMCC13023_04870	1.519e-34	137.0	COG4668@1|root,COG4668@2|Bacteria,2IKK6@201174|Actinobacteria,4FPCZ@85023|Microbacteriaceae	201174|Actinobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	mtlF	-	2.7.1.197,2.7.1.202	ko:K02768,ko:K02798,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273,M00274	R02704,R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2
SRR25158351_k127_2058481_5	558173.CDOO_06310	0.0002622	49.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,22KGG@1653|Corynebacteriaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRR25158351_k127_2058481_2	1120950.KB892740_gene2559	1.284e-47	174.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4DQKG@85009|Propionibacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158351_k127_2058481_4	1205910.B005_1997	6.096e-34	132.0	COG0238@1|root,COG0629@1|root,COG0238@2|Bacteria,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4EFMR@85012|Streptosporangiales	201174|Actinobacteria	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_2058481_1	1504319.GM45_1555	3.341e-63	220.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158351_k127_2058481_3	1504319.GM45_1560	1.33e-42	157.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,3UWQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158351_k127_2058481_0	1032480.MLP_53100	3.653e-91	306.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4DN5G@85009|Propionibacteriales	201174|Actinobacteria	L	Xylose isomerase-like TIM barrel	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158351_k127_2061164_0	1122611.KB903943_gene1536	1.564e-96	328.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4EG3M@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158351_k127_2061164_1	266940.Krad_0491	4.377e-61	217.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158351_k127_206708_0	1504319.GM45_0755	2.691e-251	785.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,3UWCW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Cytochrome b/b6/petB	qcrB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158351_k127_206708_1	1504319.GM45_0760	3.765e-112	368.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,3UWCF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158351_k127_2071614_1	1385520.N802_13815	1.42e-22	108.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FGBX@85021|Intrasporangiaceae	201174|Actinobacteria	T	DNA-binding protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158351_k127_2071614_0	1214101.BN159_6366	1.146e-271	843.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158351_k127_213114_1	1123258.AQXZ01000006_gene149	5.39e-30	119.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4FW1U@85025|Nocardiaceae	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158351_k127_213114_0	1306174.JODP01000006_gene3620	1.273e-47	172.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158351_k127_213176_1	656024.FsymDg_3115	3.682e-48	177.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4EREQ@85013|Frankiales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_213176_0	1504319.GM45_1105	4.8e-76	261.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,3UWA7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158351_k127_22147_0	494419.ALPM01000076_gene1553	5.548e-136	447.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,1W7GU@1268|Micrococcaceae	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158351_k127_225332_2	680646.RMDY18_08380	6.493e-18	83.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,1W7ST@1268|Micrococcaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158351_k127_225332_1	670292.JH26_03880	3.013e-67	237.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158351_k127_225332_3	1078020.KEK_13483	1.486e-11	68.0	COG1977@1|root,COG1977@2|Bacteria,2IQIT@201174|Actinobacteria,23B79@1762|Mycobacteriaceae	201174|Actinobacteria	H	Molybdopterin converting factor, small subunit	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158351_k127_225332_0	1095772.CAHH01000041_gene1268	1.75e-127	415.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158351_k127_228358_2	1206101.AZXC01000001_gene4304	2.331e-13	74.0	COG0477@1|root,COG1846@1|root,COG0477@2|Bacteria,COG1846@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_228358_1	685035.ADAE01000008_gene3040	2.918e-29	124.0	2EQUS@1|root,33KPM@2|Bacteria,1QY6Y@1224|Proteobacteria,2URR2@28211|Alphaproteobacteria,2KEN6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_228358_0	1032480.MLP_43130	1.29e-52	190.0	COG1028@1|root,COG1028@2|Bacteria,2I9MD@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158351_k127_229315_4	1504319.GM45_3390	9.686e-48	173.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,3UXBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158351_k127_229315_1	1157634.KB913011_gene494	5.051e-67	237.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt ABC transporter	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158351_k127_229315_7	561175.KB894094_gene2102	1.559e-15	80.0	COG0310@1|root,COG0310@2|Bacteria,2GRUA@201174|Actinobacteria	201174|Actinobacteria	P	PDGLE domain	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	PDGLE
SRR25158351_k127_229315_3	1146883.BLASA_3796	3.144e-65	229.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria,4ESI7@85013|Frankiales	201174|Actinobacteria	P	Cobalt uptake substrate-specific transmembrane region	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158351_k127_229315_10	1122138.AQUZ01000009_gene4128	0.0002801	46.0	2DYK7@1|root,34A68@2|Bacteria,2HZGV@201174|Actinobacteria,4DSRQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158351_k127_229315_0	288705.RSal33209_2409	1.714e-80	272.0	COG1435@1|root,COG1435@2|Bacteria,2GP1W@201174|Actinobacteria,1W8G5@1268|Micrococcaceae	201174|Actinobacteria	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158351_k127_229315_5	1121272.KB903290_gene4729	1.394e-30	128.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4DEM5@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158351_k127_229315_8	37919.EP51_24195	3.516e-15	89.0	COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria,4FWC4@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
SRR25158351_k127_229315_2	33898.JRHJ01000049_gene7723	1.379e-65	230.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria	201174|Actinobacteria	S	protein hemolysin III	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158351_k127_229315_6	196162.Noca_4461	2.02e-22	96.0	COG4898@1|root,COG4898@2|Bacteria,2IKPX@201174|Actinobacteria,4DRBT@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
SRR25158351_k127_243276_1	680646.RMDY18_18010	6.799e-21	94.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,1W7RX@1268|Micrococcaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158351_k127_243276_0	1121017.AUFG01000003_gene3404	2.665e-105	351.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4FGFK@85021|Intrasporangiaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158351_k127_243276_2	479433.Caci_7148	1.723e-05	51.0	COG4166@1|root,COG4166@2|Bacteria,2IIU5@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158351_k127_247806_0	211114.JOEF01000026_gene306	1.033e-62	229.0	COG1232@1|root,COG1232@2|Bacteria,2I3QR@201174|Actinobacteria,4DZ1J@85010|Pseudonocardiales	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_247806_1	1449976.KALB_1719	2.641e-06	51.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4DZJS@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158351_k127_248483_0	105425.BBPL01000007_gene7325	3.599e-97	328.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria,2NFE8@228398|Streptacidiphilus	201174|Actinobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158351_k127_248483_1	479431.Namu_3542	5.237e-91	308.0	COG1485@1|root,COG1485@2|Bacteria,2GNQA@201174|Actinobacteria,4EU0K@85013|Frankiales	201174|Actinobacteria	S	AFG1-like ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
SRR25158351_k127_25772_0	1123278.KB893393_gene5607	3.774e-48	179.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158351_k127_25772_1	1235755.ANAM01000010_gene1914	3.35e-16	82.0	COG0697@1|root,COG0697@2|Bacteria,1TQTG@1239|Firmicutes,4HCMU@91061|Bacilli,4H0AM@90964|Staphylococcaceae	91061|Bacilli	EG	EamA-like transporter family	ywfM	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
SRR25158351_k127_259707_0	529884.Rhola_00001430	1.933e-114	384.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria,4FK9A@85023|Microbacteriaceae	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158351_k127_259731_0	1449353.JQMQ01000005_gene3922	0.0	1103.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,2NF2C@228398|Streptacidiphilus	201174|Actinobacteria	U	SecA preprotein cross-linking domain	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158351_k127_263899_1	67267.JNXT01000031_gene2504	1.244e-67	239.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158351_k127_263899_0	1504319.GM45_6000	1.874e-218	689.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,3UW70@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158351_k127_263899_2	1313172.YM304_13280	1.287e-23	107.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
SRR25158351_k127_265525_3	110319.CF8_1160	1.31e-22	102.0	COG3022@1|root,COG3022@2|Bacteria,2GJPM@201174|Actinobacteria,4DPK6@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0246 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
SRR25158351_k127_265525_0	1089455.MOPEL_027_00150	2.171e-181	574.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4F7NZ@85018|Dermatophilaceae	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_265525_1	1032480.MLP_13840	7.969e-133	430.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4DWPF@85009|Propionibacteriales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158351_k127_265525_4	929794.CALV01000035_gene989	1.332e-07	55.0	2AEA1@1|root,31447@2|Bacteria,1PTHK@1224|Proteobacteria,2V5D4@28211|Alphaproteobacteria,48UG9@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_265525_2	391037.Sare_0141	7.42e-55	203.0	COG2271@1|root,COG2271@2|Bacteria,2HB3P@201174|Actinobacteria,4DCV1@85008|Micromonosporales	201174|Actinobacteria	G	PFAM major facilitator superfamily MFS_1	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0022857,GO:0042221,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158351_k127_268162_1	1158050.KB895453_gene1183	1.024e-68	240.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,1W89R@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158351_k127_268162_2	1463861.JNXE01000028_gene2946	3.353e-09	60.0	290XR@1|root,2ZNJH@2|Bacteria,2IQ97@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_268162_0	465541.ATCJ01000005_gene2810	1.152e-165	531.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria	201174|Actinobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158351_k127_268630_0	1894.JOER01000011_gene2079	4.213e-55	201.0	COG0303@1|root,COG0303@2|Bacteria,2GP1B@201174|Actinobacteria	201174|Actinobacteria	H	molybdopterin	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158351_k127_268630_2	1219045.BV98_002889	0.0004207	45.0	2E4CR@1|root,32Z86@2|Bacteria	2|Bacteria	S	NADH-dependant formate dehydrogenase delta subunit FdsD	fdsD	-	1.17.1.9	ko:K00126	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	FdsD
SRR25158351_k127_268630_1	379066.GAU_2385	1.409e-21	94.0	COG3383@1|root,COG3383@2|Bacteria,1ZTXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158351_k127_281603_1	469609.HMPREF0847_01163	8.589e-09	59.0	COG4912@1|root,COG4912@2|Bacteria,1V2AI@1239|Firmicutes,4IRCV@91061|Bacilli	91061|Bacilli	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158351_k127_281603_0	266940.Krad_0491	1.116e-137	451.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria	201174|Actinobacteria	NU	Alpha beta hydrolase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158351_k127_28797_0	477641.MODMU_1734	8.89e-49	180.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4ESGS@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158351_k127_28797_1	351607.Acel_0763	0.0001873	51.0	COG1316@1|root,COG1316@2|Bacteria,2GNGN@201174|Actinobacteria,4EWPJ@85013|Frankiales	201174|Actinobacteria	K	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158351_k127_288631_0	1283283.ATXA01000017_gene3752	1.12e-79	268.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4ESIC@85013|Frankiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158351_k127_288631_1	1160718.SU9_14461	8.423e-60	216.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158351_k127_288631_3	443255.SCLAV_2940	1.357e-07	57.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158351_k127_29479_0	1869.MB27_28275	2.365e-31	143.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14645,ko:K14743	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158351_k127_297732_0	1121946.AUAX01000003_gene1654	2.849e-133	436.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4D8TI@85008|Micromonosporales	201174|Actinobacteria	P	drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_297732_3	529884.Rhola_00002470	1.324e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,2HSNY@201174|Actinobacteria,4FPMD@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158351_k127_297732_2	479435.Kfla_5999	9.886e-92	315.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQRB@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158351_k127_297732_5	1504319.GM45_4250	7.427e-17	81.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	zf-CDGSH
SRR25158351_k127_297732_4	979556.MTES_1495	6.308e-35	142.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4FNGN@85023|Microbacteriaceae	201174|Actinobacteria	M	Sortase family	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158351_k127_297732_1	1504319.GM45_2870	3.482e-95	321.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,3UXSZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158351_k127_299501_1	1122130.AUHN01000005_gene2451	3.452e-36	157.0	COG2385@1|root,COG2385@2|Bacteria,2IEPH@201174|Actinobacteria	201174|Actinobacteria	D	SpoIID LytB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LGFP,SpoIID
SRR25158351_k127_299501_0	1081644.IMCC13023_02170	7.548e-177	578.0	COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4FRW2@85023|Microbacteriaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
SRR25158351_k127_299501_3	477641.MODMU_0787	2e-23	102.0	COG4339@1|root,COG4339@2|Bacteria,2IQ60@201174|Actinobacteria,4ETC4@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031
SRR25158351_k127_299501_2	1027371.GOALK_072_00120	3.908e-26	110.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4GAT1@85026|Gordoniaceae	201174|Actinobacteria	U	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158351_k127_301174_1	871585.BDGL_001435	5.376e-21	101.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,3NKP6@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
SRR25158351_k127_301174_0	543632.JOJL01000018_gene9000	3.59e-62	224.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4DG3A@85008|Micromonosporales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	ybeK	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158351_k127_312555_2	1907.SGLAU_10270	8.138e-46	171.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158351_k127_312555_1	469371.Tbis_1249	1.176e-114	376.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4DZTC@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158351_k127_312555_0	1048339.KB913029_gene4683	2.461e-183	584.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4ESAT@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158351_k127_32329_7	390989.JOEG01000006_gene916	2.929e-05	49.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4DD3G@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158351_k127_32329_4	1193181.BN10_590009	2.568e-46	169.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4FGYG@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158351_k127_32329_5	105420.BBPO01000043_gene3643	6.574e-31	132.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,2NFGB@228398|Streptacidiphilus	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158351_k127_32329_2	110319.CF8_2039	1.082e-62	220.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4DQ8M@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_32329_6	1096756.ATKN01000005_gene2795	1.074e-28	119.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,1W9DA@1268|Micrococcaceae	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158351_k127_32329_1	1184607.AUCHE_05_06140	9.554e-91	301.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4F6K1@85018|Dermatophilaceae	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158351_k127_32329_3	1449347.JQLN01000004_gene6586	3.094e-54	194.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,2M2S5@2063|Kitasatospora	201174|Actinobacteria	E	Dehydroquinase class II	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158351_k127_32329_0	1122138.AQUZ01000011_gene5036	2.625e-116	379.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4DN6F@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158351_k127_323699_0	1184607.AUCHE_05_01710	9.691e-110	364.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4F6B5@85018|Dermatophilaceae	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158351_k127_32666_0	471852.Tcur_0234	3.206e-194	612.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4EGHS@85012|Streptosporangiales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158351_k127_32666_3	196162.Noca_1466	1.22e-70	247.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4DQTE@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158351_k127_32666_4	1237500.ANBA01000011_gene3518	0.0004528	48.0	COG1075@1|root,COG1075@2|Bacteria,2IAEU@201174|Actinobacteria,4EQDC@85012|Streptosporangiales	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158351_k127_32666_2	1348663.KCH_38750	9.827e-80	269.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,2M0KQ@2063|Kitasatospora	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158351_k127_32666_1	351607.Acel_2125	1.811e-132	427.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4ERVG@85013|Frankiales	201174|Actinobacteria	G	Fructose-bisphosphate aldolase, class II	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158351_k127_328238_0	1380393.JHVP01000006_gene4036	1.742e-247	773.0	COG1012@1|root,COG1012@2|Bacteria,2GJZE@201174|Actinobacteria,4ERPX@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158351_k127_328238_1	1298863.AUEP01000004_gene2219	1.115e-112	372.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4DNF7@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158351_k127_328238_2	1123322.KB904693_gene4546	1.261e-40	154.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158351_k127_328238_3	1214242.B446_21910	5.483e-38	147.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the UPF0336 family	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158351_k127_328238_4	1463864.JOGO01000020_gene3435	8.515e-23	98.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158351_k127_328546_0	1449346.JQMO01000003_gene3510	3.295e-75	261.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,2M1S9@2063|Kitasatospora	201174|Actinobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158351_k127_328546_1	1235801.C822_00086	8.32e-28	124.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae	91061|Bacilli	S	DAK2 domain fusion protein YloV	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158351_k127_328546_2	585531.HMPREF0063_11204	1.46e-10	62.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4DSDU@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158351_k127_328555_3	471852.Tcur_1647	1.617e-50	182.0	2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria,4EJAB@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158351_k127_328555_2	66377.JOBH01000001_gene1174	2.209e-60	213.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpE	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158351_k127_328555_0	397278.JOJN01000006_gene1060	2.379e-109	359.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4DNKW@85009|Propionibacteriales	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158351_k127_328555_1	1003195.SCAT_1389	1.187e-81	279.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158351_k127_328555_4	479433.Caci_5890	2.282e-42	164.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria	201174|Actinobacteria	S	Zn-ribbon protein, possibly nucleic acid-binding	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158351_k127_335869_2	1121933.AUHH01000047_gene919	1.596e-81	273.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4DNQN@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158351_k127_335869_0	1380347.JNII01000005_gene3065	8.579e-232	723.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4ES9G@85013|Frankiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158351_k127_335869_3	1283283.ATXA01000017_gene3762	2.994e-52	194.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4ESRA@85013|Frankiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158351_k127_335869_1	1120950.KB892812_gene6976	3.588e-86	294.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4DN8Z@85009|Propionibacteriales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158351_k127_345123_2	105425.BBPL01000018_gene119	6.079e-69	235.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,2NG5J@228398|Streptacidiphilus	201174|Actinobacteria	L	ERCC3/RAD25/XPB C-terminal helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158351_k127_345123_0	1463920.JOGB01000067_gene6334	3.198e-93	307.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria	201174|Actinobacteria	L	helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158351_k127_345123_1	1463934.JOCF01000002_gene3045	3.462e-79	273.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
SRR25158351_k127_352612_4	1237500.ANBA01000015_gene2283	2.688e-14	74.0	COG1109@1|root,COG1109@2|Bacteria,2GJ3Q@201174|Actinobacteria,4EHG1@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pmmB	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158351_k127_352612_2	316274.Haur_1963	1.996e-41	168.0	COG0490@1|root,COG1226@1|root,COG4651@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,COG4651@2|Bacteria,2G5QY@200795|Chloroflexi,376DS@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158351_k127_352612_1	66875.JODY01000023_gene5681	1.408e-46	177.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158351_k127_352612_3	2002.JOEQ01000029_gene8217	5.254e-41	156.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4EJS2@85012|Streptosporangiales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158351_k127_352612_0	1048339.KB913029_gene1722	9.568e-73	260.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4ERJW@85013|Frankiales	201174|Actinobacteria	T	protein phosphatase 2C domain protein	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158351_k127_352612_5	1157640.AQWO01000001_gene6464	1.292e-09	61.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_359988_3	1194972.MVAC_23991	3.095e-17	84.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,232XE@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	prr_2	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_359988_2	1306174.JODP01000016_gene7157	5.157e-68	235.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158351_k127_359988_0	1386089.N865_10040	3.699e-229	717.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FE6A@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158351_k127_359988_1	1123320.KB889675_gene4065	1.567e-165	532.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158351_k127_36777_2	930171.Asphe3_15360	1.726e-40	164.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,1W808@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_36777_1	479435.Kfla_2844	4.564e-65	233.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4DPV8@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_36777_0	1155718.KB891854_gene2856	7.654e-68	233.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158351_k127_371817_1	67275.JOAP01000040_gene3487	1.459e-43	159.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria	201174|Actinobacteria	S	Mov34 MPN PAD-1 family	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158351_k127_371817_4	269800.Tfu_2371	7.185e-28	120.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4EJ1I@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158351_k127_371817_2	1048339.KB913029_gene5024	2.388e-37	142.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4ESZD@85013|Frankiales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158351_k127_371817_3	1032480.MLP_39090	9.749e-31	123.0	2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4DRHQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
SRR25158351_k127_371817_0	1504319.GM45_3320	1.512e-74	254.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,3UWAV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158351_k127_374494_5	935839.JAGJ01000015_gene2132	5.127e-05	46.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4F4EG@85017|Promicromonosporaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158351_k127_374494_1	1123320.KB889730_gene5990	4.307e-91	303.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria	201174|Actinobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158351_k127_374494_0	351607.Acel_0019	7.305e-149	490.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158351_k127_374494_3	1304865.JAGF01000001_gene1276	6.136e-71	246.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4F0UK@85016|Cellulomonadaceae	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158351_k127_374494_4	1048339.KB913029_gene1720	1.679e-67	241.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4ERJZ@85013|Frankiales	201174|Actinobacteria	M	PFAM penicillin-binding protein transpeptidase	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158351_k127_374494_2	2055.JNXA01000005_gene599	4.31e-76	259.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4GC7U@85026|Gordoniaceae	201174|Actinobacteria	D	Cell cycle protein	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158351_k127_376661_2	1504319.GM45_6185	3.024e-114	375.0	COG2211@1|root,COG2211@2|Bacteria,2GP5J@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
SRR25158351_k127_376661_0	1504319.GM45_6180	5.003e-247	767.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,3UW95@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158351_k127_376661_1	367299.JOEE01000004_gene1264	1.051e-126	409.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4FF6H@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_378973_0	1237500.ANBA01000010_gene789	2.123e-152	485.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4EFFK@85012|Streptosporangiales	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158351_k127_378973_2	1077972.ARGLB_051_01740	6.331e-45	171.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,1W967@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158351_k127_378973_1	1089544.KB912942_gene3031	2.626e-64	222.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4DXYQ@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
SRR25158351_k127_380392_1	383372.Rcas_0521	4.533e-16	79.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi,3764G@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158351_k127_380392_0	926564.KI911649_gene1718	5.567e-69	241.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria,4F43Y@85017|Promicromonosporaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
SRR25158351_k127_393931_3	1869.MB27_19565	2.195e-34	132.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4DA3H@85008|Micromonosporales	201174|Actinobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_393931_1	1504319.GM45_5790	3.089e-59	211.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,3UWSN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Nucleoside diphosphate kinase	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158351_k127_393931_4	479432.Sros_7285	2.752e-06	54.0	2E69F@1|root,330XE@2|Bacteria,2I8BM@201174|Actinobacteria,4ERBH@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4233)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4233
SRR25158351_k127_393931_0	1273125.Rrhod_2237	2.716e-155	502.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4FV2N@85025|Nocardiaceae	201174|Actinobacteria	H	Mur ligase family, glutamate ligase domain	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_393931_2	1120948.KB903217_gene1125	2.433e-38	144.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4DXKT@85010|Pseudonocardiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158351_k127_395526_0	767029.HMPREF9154_0434	3.871e-78	267.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DNF3@85009|Propionibacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158351_k127_395526_1	479435.Kfla_6426	2.022e-70	241.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4DNMZ@85009|Propionibacteriales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158351_k127_39758_2	1504319.GM45_6270	8.019e-82	276.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,3UXKH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Ami_3	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
SRR25158351_k127_39758_4	1504319.GM45_6275	1.13e-46	169.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,3UWW6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158351_k127_39758_1	1504319.GM45_6280	3.43e-161	511.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,3UWDR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_39758_0	1504319.GM45_6290	4.36e-180	578.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,3UWJN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	MviN-like protein	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158351_k127_39758_3	1504319.GM45_6295	2.335e-62	229.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,Amidase_6,GHL10,fn3
SRR25158351_k127_406039_2	1380356.JNIK01000001_gene2229	7.461e-21	95.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4ES5C@85013|Frankiales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158351_k127_406039_1	235985.BBPN01000007_gene3310	6.868e-131	426.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,2NGAY@228398|Streptacidiphilus	201174|Actinobacteria	K	HrcA protein C terminal domain	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR25158351_k127_406039_0	1894.JOER01000088_gene3393	2.181e-133	430.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158351_k127_419874_0	1048339.KB913029_gene55	2.37e-322	994.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4ES8A@85013|Frankiales	201174|Actinobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_419874_2	68223.JNZY01000009_gene3006	1.901e-88	314.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Peptidase_C14,SBP_bac_5
SRR25158351_k127_419874_1	1463936.JOJI01000018_gene7671	6.759e-94	317.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158351_k127_419874_3	1283283.ATXA01000005_gene2129	5.292e-48	179.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4EUYS@85013|Frankiales	201174|Actinobacteria	E	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158351_k127_420278_1	1172186.KB911466_gene1687	3.528e-12	67.0	COG4898@1|root,COG4898@2|Bacteria,2IKPX@201174|Actinobacteria,23A6T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
SRR25158351_k127_420278_0	1336235.JAEG01000005_gene3552	3.502e-66	240.0	COG0697@1|root,COG0697@2|Bacteria,1R4HR@1224|Proteobacteria,2U206@28211|Alphaproteobacteria,4BDIT@82115|Rhizobiaceae	28211|Alphaproteobacteria	EG	permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_429362_2	1121933.AUHH01000012_gene3666	5.247e-72	248.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,4DNNY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
SRR25158351_k127_429362_3	414996.IL38_15490	2.306e-64	229.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,408AE@622450|Actinopolysporales	201174|Actinobacteria	BDLTU	Phosphatidylinositol	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_429362_5	1048339.KB913029_gene4218	5.755e-56	201.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4ESX0@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158351_k127_429362_4	935866.JAER01000007_gene339	1.95e-58	210.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4DQ6B@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158351_k127_429362_0	43354.JOIJ01000002_gene4176	2.19e-92	310.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4E1PW@85010|Pseudonocardiales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158351_k127_429362_6	196162.Noca_2621	6.492e-07	53.0	2EGVE@1|root,33AMN@2|Bacteria,2HZDP@201174|Actinobacteria,4DSA4@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_429362_1	67257.JODR01000015_gene5906	4.148e-92	307.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158351_k127_449142_1	469371.Tbis_2846	1.598e-76	261.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158351_k127_449142_0	1429046.RR21198_3191	1.812e-87	295.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4FY6W@85025|Nocardiaceae	201174|Actinobacteria	I	enoyl-CoA hydratase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158351_k127_452407_2	1504319.GM45_0625	1.269e-67	233.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158351_k127_452407_0	1172188.KB911821_gene2080	2.927e-186	606.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4FFEC@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158351_k127_452407_1	479435.Kfla_2685	6.943e-73	249.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4DPMN@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158351_k127_455628_3	1123320.KB889676_gene2822	7.086e-68	234.0	COG0331@1|root,COG0511@1|root,COG0331@2|Bacteria,COG0511@2|Bacteria,2GME0@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Acyl transferase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158351_k127_455628_2	479435.Kfla_2567	4.295e-107	357.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4DP78@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158351_k127_455628_6	105420.BBPO01000052_gene1841	7.971e-30	119.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,2NJHZ@228398|Streptacidiphilus	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158351_k127_455628_1	1476876.JOJO01000014_gene7093	1.753e-150	487.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158351_k127_455628_0	2045.KR76_18745	1.036e-202	640.0	COG4799@1|root,COG4799@2|Bacteria,2I16G@201174|Actinobacteria,4DNAY@85009|Propionibacteriales	201174|Actinobacteria	I	Malonate decarboxylase gamma subunit (MdcE)	accD6	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009317,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:1901575,GO:1901576,GO:1902494	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18472	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04386	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158351_k127_455628_4	1122138.AQUZ01000004_gene935	2.751e-55	199.0	299E4@1|root,2ZWGX@2|Bacteria,2GM90@201174|Actinobacteria,4DQ7U@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3145
SRR25158351_k127_455628_5	118168.MC7420_5024	7.046e-38	149.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1G3ZT@1117|Cyanobacteria,1HF1E@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3445)	-	-	1.14.13.238	ko:K22342	-	-	-	-	ko00000,ko01000	-	-	-	DUF3445
SRR25158351_k127_456872_3	351607.Acel_0404	1.204e-38	147.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,4ET34@85013|Frankiales	201174|Actinobacteria	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158351_k127_456872_1	1449355.JQNR01000003_gene1037	2.396e-104	342.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158351_k127_456872_0	471853.Bcav_1241	4.881e-123	411.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158351_k127_456872_2	1123065.ATWL01000008_gene2411	6.859e-43	175.0	COG5401@1|root,COG5401@2|Bacteria,2GJ5Y@201174|Actinobacteria	201174|Actinobacteria	M	Lipoprotein lpqB	lpqB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
SRR25158351_k127_460090_2	105425.BBPL01000012_gene1960	2.36e-126	408.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,2NG9M@228398|Streptacidiphilus	201174|Actinobacteria	E	TOBE domain	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158351_k127_460090_1	1306174.JODP01000016_gene7159	9.831e-133	434.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158351_k127_460090_0	526225.Gobs_1721	4.343e-203	636.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4ERRA@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_461759_0	1504319.GM45_1090	2.609e-140	461.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,3UWG5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158351_k127_461759_1	935866.JAER01000036_gene3431	6.731e-126	419.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4DN64@85009|Propionibacteriales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158351_k127_463281_0	1095772.CAHH01000058_gene1431	2.901e-130	422.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158351_k127_463281_2	585531.HMPREF0063_12367	5.28e-103	341.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4DNDW@85009|Propionibacteriales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158351_k127_463281_1	1123320.KB889675_gene4072	8.581e-112	366.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158351_k127_463281_3	479433.Caci_1532	1.229e-69	239.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158351_k127_46578_0	1123322.KB904651_gene392	4.533e-187	590.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158351_k127_46578_1	397278.JOJN01000002_gene100	3.732e-166	529.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DN1G@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158351_k127_46578_2	1120950.KB892783_gene330	1.683e-141	462.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4DN6M@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	gabD2	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_47613_0	1193181.BN10_680009	6.95e-188	601.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4FEFA@85021|Intrasporangiaceae	201174|Actinobacteria	D	Cell division protein FtsK	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158351_k127_476688_1	452652.KSE_14400	4.728e-80	274.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,2M07A@2063|Kitasatospora	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158351_k127_476688_2	633147.Olsu_0942	1.494e-48	179.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CVSW@84998|Coriobacteriia	84998|Coriobacteriia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158351_k127_476688_0	351607.Acel_1338	6.242e-93	310.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4EREV@85013|Frankiales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158351_k127_479188_1	570268.ANBB01000046_gene1329	2.521e-34	132.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4EFRR@85012|Streptosporangiales	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158351_k127_479188_0	1894.JOER01000060_gene4286	3.668e-100	334.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158351_k127_479188_2	1504319.GM45_4635	1.74e-18	85.0	COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2754c	Thy1
SRR25158351_k127_479675_2	1043493.BBLU01000001_gene993	4.536e-60	212.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158351_k127_479675_1	196162.Noca_2496	1.051e-65	230.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4DQ4Q@85009|Propionibacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158351_k127_479675_0	1048339.KB913029_gene4083	8.63e-89	300.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4ERDV@85013|Frankiales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158351_k127_482570_0	1124991.MU9_2899	3.688e-07	59.0	2C8Q6@1|root,2Z882@2|Bacteria,1PY18@1224|Proteobacteria,1RRKX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Packaged DNA stabilization protein gp10	-	-	-	-	-	-	-	-	-	-	-	-	Phage_stabilise
SRR25158351_k127_483955_3	477641.MODMU_4550	3.681e-21	98.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4ESEK@85013|Frankiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158351_k127_483955_1	106370.Francci3_3719	1.357e-64	232.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4ESEI@85013|Frankiales	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
SRR25158351_k127_483955_0	66373.JOFQ01000005_gene3877	5.316e-155	496.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158351_k127_483955_2	28444.JODQ01000002_gene3921	6.257e-34	131.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4EK8U@85012|Streptosporangiales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158351_k127_483955_4	585531.HMPREF0063_11769	9.521e-12	66.0	2EI4A@1|root,33BVN@2|Bacteria,2GX45@201174|Actinobacteria,4DSKQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_49388_11	1210046.B277_01714	1.359e-29	123.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4FFHZ@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158351_k127_49388_4	196162.Noca_3653	1.8e-152	495.0	COG2070@1|root,COG2070@2|Bacteria,2I93H@201174|Actinobacteria	201174|Actinobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158351_k127_49388_8	935866.JAER01000013_gene1057	5.97e-81	272.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4DPIQ@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158351_k127_49388_9	1123320.KB889585_gene1779	2.881e-74	260.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158351_k127_49388_7	1095767.CAHD01000090_gene1949	2.748e-85	285.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4F0PN@85016|Cellulomonadaceae	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158351_k127_49388_0	717772.THIAE_01925	0.0	1234.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,4605A@72273|Thiotrichales	72273|Thiotrichales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158351_k127_49388_12	1380354.JIAN01000008_gene3453	1.62e-19	93.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	2.3.2.29,2.5.1.18,3.8.1.2	ko:K00799,ko:K01560,ko:K21420	ko00361,ko00480,ko00625,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00625,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418	-	R03522,R05287,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11547,R11548,R11905	RC00004,RC00064,RC00069,RC00697,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
SRR25158351_k127_49388_10	1032480.MLP_47510	4.455e-49	185.0	COG0345@1|root,COG0345@2|Bacteria,2GKMG@201174|Actinobacteria	201174|Actinobacteria	E	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158351_k127_49388_2	1048339.KB913029_gene1385	7.316e-164	533.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4ERVT@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158351_k127_49388_5	1120950.KB892742_gene3041	2.755e-100	329.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4DP0B@85009|Propionibacteriales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158351_k127_49388_1	1504319.GM45_3690	4.517e-191	605.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,3UWDX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ACT domain	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158351_k127_49388_3	1245475.ANAE01000161_gene915	5.1e-155	498.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4EGS7@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158351_k127_49388_6	1121017.AUFG01000019_gene2400	6.206e-100	335.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4FEHS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158351_k127_494344_1	479435.Kfla_2963	1.536e-06	51.0	COG0457@1|root,COG0457@2|Bacteria,2I2JF@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_494344_0	1150599.MPHLEI_08204	8.891e-92	308.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,23462@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2773c	DapB_C,DapB_N
SRR25158351_k127_494344_2	479435.Kfla_2954	6.371e-05	46.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4DNY1@85009|Propionibacteriales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158351_k127_501818_2	219305.MCAG_01243	3.962e-28	117.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4D8QG@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158351_k127_501818_0	1504319.GM45_1000	3.586e-245	765.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,3UXB3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158351_k127_501818_1	1122602.ATXP01000006_gene95	7.182e-58	212.0	2DBIT@1|root,2Z9GU@2|Bacteria,2GN03@201174|Actinobacteria,1WCDR@1268|Micrococcaceae	201174|Actinobacteria	S	Carotene biosynthesis associated membrane protein	mptB	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
SRR25158351_k127_50182_1	1283299.AUKG01000002_gene5058	2.054e-20	99.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4CQ1P@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158351_k127_50182_2	1283299.AUKG01000002_gene5058	1.299e-18	92.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4CQ1P@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158351_k127_50182_0	1370120.AUWR01000012_gene1268	3.248e-28	117.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria,23CEX@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Indigoidine synthase A like protein	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158351_k127_511730_1	44060.JODL01000021_gene4832	1.563e-20	91.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria	201174|Actinobacteria	G	fructose-bisphosphate aldolase	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158351_k127_511730_0	227882.SAV_4547	8.731e-197	616.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158351_k127_521096_1	1386089.N865_09815	9.93e-85	287.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4FF19@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158351_k127_521096_0	67352.JODS01000007_gene4569	2.947e-94	320.0	COG4346@1|root,COG4346@2|Bacteria,2GITT@201174|Actinobacteria	201174|Actinobacteria	O	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	pmt	GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SRR25158351_k127_527670_0	926569.ANT_02360	7.839e-72	249.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	MA20_36825	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR25158351_k127_527670_1	1278073.MYSTI_04090	1.908e-21	108.0	COG3568@1|root,COG3568@2|Bacteria,1N29G@1224|Proteobacteria,438Z7@68525|delta/epsilon subdivisions,2X8PT@28221|Deltaproteobacteria,2YY8K@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158351_k127_527670_2	408672.NBCG_05659	4.241e-13	69.0	COG0695@1|root,COG0695@2|Bacteria,2IQF9@201174|Actinobacteria,4DRV4@85009|Propionibacteriales	201174|Actinobacteria	O	Glutaredoxin	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
SRR25158351_k127_532402_1	1410634.JHVD01000006_gene1155	1.541e-13	78.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria	201174|Actinobacteria	S	phosphoribosyltransferase	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158351_k127_532402_0	469371.Tbis_3093	1.32e-55	195.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4DYMM@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS2	GO:0003674,GO:0003824,GO:0016740,GO:0016765,GO:0033850	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158351_k127_53505_2	928724.SacglDRAFT_01495	1.519e-34	137.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4E2M3@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158351_k127_53505_0	35754.JNYJ01000043_gene4550	1.006e-127	411.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4DB6H@85008|Micromonosporales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158351_k127_53505_1	1003195.SCAT_1575	1.205e-39	150.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158351_k127_536239_0	1211815.CBYP010000050_gene629	1.119e-296	916.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4ERTY@85013|Frankiales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158351_k127_536239_1	1122622.ATWJ01000009_gene3366	2.249e-131	427.0	COG1064@1|root,COG1064@2|Bacteria,2GNNY@201174|Actinobacteria,4FFHD@85021|Intrasporangiaceae	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_536239_3	529884.Rhola_00003500	9.113e-105	352.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4FKGR@85023|Microbacteriaceae	201174|Actinobacteria	E	Aminotransferase class I and II	metC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_536239_4	1304865.JAGF01000001_gene928	1.524e-32	132.0	COG0350@1|root,COG0350@2|Bacteria,2IHP1@201174|Actinobacteria,4F1IB@85016|Cellulomonadaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158351_k127_536239_2	529884.Rhola_00003400	6.113e-129	420.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria,4FN1I@85023|Microbacteriaceae	201174|Actinobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
SRR25158351_k127_537022_0	1348663.KCH_30420	0.0	1427.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,2M1SG@2063|Kitasatospora	201174|Actinobacteria	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158351_k127_537975_2	1463936.JOJI01000035_gene8014	6.948e-64	222.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158351_k127_537975_0	1283283.ATXA01000002_gene2503	6.922e-229	719.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4ERX1@85013|Frankiales	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158351_k127_537975_1	67257.JODR01000008_gene3578	6.358e-68	233.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158351_k127_550903_3	1906.SFRA_32185	5.768e-10	67.0	2EID2@1|root,33C4E@2|Bacteria,2IG1H@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4245)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4245
SRR25158351_k127_550903_2	1504319.GM45_3140	2.302e-10	63.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,3UWZG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158351_k127_550903_0	471853.Bcav_1101	1.846e-108	366.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158351_k127_550903_1	65497.JODV01000001_gene3797	3.299e-84	283.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DX3Z@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158351_k127_552342_0	298654.FraEuI1c_0673	7.026e-110	359.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4ES3C@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158351_k127_552342_1	1120959.ATXF01000008_gene547	2.512e-25	111.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4FPQI@85023|Microbacteriaceae	201174|Actinobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158351_k127_55711_0	358823.DF19_40680	6.553e-62	224.0	COG0697@1|root,COG0697@2|Bacteria,2GP9G@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918,EamA
SRR25158351_k127_55711_1	196162.Noca_3162	8.371e-60	215.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4DQH9@85009|Propionibacteriales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158351_k127_55711_2	1713.JOFV01000004_gene3414	9.377e-19	89.0	2E45J@1|root,32Z1K@2|Bacteria,2GR89@201174|Actinobacteria,4F1GI@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM branched-chain amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158351_k127_55711_3	1120917.AQXM01000063_gene2081	0.0004131	46.0	COG5010@1|root,COG5010@2|Bacteria,2IFHE@201174|Actinobacteria,1W9QW@1268|Micrococcaceae	201174|Actinobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_563148_0	1120950.KB892768_gene5196	1.208e-122	399.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4DPEP@85009|Propionibacteriales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158351_k127_563148_2	1233951.IO90_02755	9.176e-17	82.0	COG2026@1|root,COG2026@2|Bacteria,4NVIF@976|Bacteroidetes,1I5T2@117743|Flavobacteriia	976|Bacteroidetes	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158351_k127_563148_3	1298860.AUEM01000001_gene1381	1.394e-09	62.0	2DPX8@1|root,333SI@2|Bacteria,2GPNK@201174|Actinobacteria,4FPUR@85023|Microbacteriaceae	201174|Actinobacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158351_k127_563148_1	471852.Tcur_2160	1.214e-45	168.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4EFWJ@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158351_k127_566287_1	1504319.GM45_3220	8.536e-64	229.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,3UWP8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Trypsin	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158351_k127_566287_2	1298863.AUEP01000007_gene355	2.011e-58	211.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4DNEI@85009|Propionibacteriales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
SRR25158351_k127_566287_4	591158.SSMG_00725	1.348e-19	89.0	2E39N@1|root,32Y97@2|Bacteria,2GQFF@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3117
SRR25158351_k127_566287_3	208444.JNYY01000005_gene6171	5.46e-39	150.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4E5GT@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158351_k127_566287_0	479432.Sros_8428	8.19e-70	241.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4EIDE@85012|Streptosporangiales	201174|Actinobacteria	S	Possible lysine decarboxylase	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158351_k127_568928_3	105425.BBPL01000002_gene6559	1.049e-48	176.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,2NHP0@228398|Streptacidiphilus	201174|Actinobacteria	S	GTP1/OBG	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158351_k127_568928_4	1120950.KB892766_gene5095	1.627e-44	162.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4DRNG@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158351_k127_568928_5	1048339.KB913029_gene4852	1.504e-27	119.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4ET3X@85013|Frankiales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158351_k127_568928_1	1463856.JOHY01000007_gene605	1.023e-221	706.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria	201174|Actinobacteria	J	ribonuclease Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158351_k127_568928_2	67352.JODS01000032_gene736	1.665e-81	277.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158351_k127_568928_0	471852.Tcur_1544	3.043e-311	959.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4EFRZ@85012|Streptosporangiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158351_k127_575322_0	529884.Rhola_00011650	4.996e-73	251.0	COG0827@1|root,COG0827@2|Bacteria,2HZV8@201174|Actinobacteria,4FRS8@85023|Microbacteriaceae	201174|Actinobacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_575322_1	471852.Tcur_3420	2.119e-51	184.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4EGB1@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158351_k127_593708_1	1280681.AUJZ01000005_gene3102	1.85e-09	63.0	COG0524@1|root,COG0524@2|Bacteria,1UYF8@1239|Firmicutes,25MKS@186801|Clostridia,4BVZA@830|Butyrivibrio	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158351_k127_593708_0	1402135.SUH3_15785	3.055e-12	72.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,3ZXIE@60136|Sulfitobacter	28211|Alphaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158351_k127_593708_2	1179773.BN6_55990	0.0004035	45.0	COG0847@1|root,COG1201@1|root,COG0847@2|Bacteria,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4EEPY@85010|Pseudonocardiales	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RNase_T
SRR25158351_k127_602169_2	1121385.AQXW01000004_gene3311	3.212e-09	66.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
SRR25158351_k127_602169_0	1463921.JODF01000028_gene3476	4.721e-23	101.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158351_k127_602169_1	1120977.JHUX01000004_gene2424	4.477e-15	78.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S9GR@1236|Gammaproteobacteria,3NP5A@468|Moraxellaceae	1236|Gammaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158351_k127_608683_2	351607.Acel_1728	1.585e-37	141.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4ESH9@85013|Frankiales	201174|Actinobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158351_k127_608683_1	646529.Desaci_4595	1.247e-42	171.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,25ZZ8@186807|Peptococcaceae	186801|Clostridia	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158351_k127_608683_0	1048339.KB913029_gene5048	8.787e-59	212.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4ESQ7@85013|Frankiales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158351_k127_610706_3	1205910.B005_3190	2.437e-58	208.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4EH7X@85012|Streptosporangiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158351_k127_610706_0	351607.Acel_0628	9.93e-230	723.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4ERR2@85013|Frankiales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158351_k127_610706_2	1120949.KB903330_gene9153	7.702e-61	216.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria,4DC2S@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158351_k127_610706_1	234621.RER_48460	3.037e-91	306.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FU3N@85025|Nocardiaceae	201174|Actinobacteria	C	transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158351_k127_612475_0	2074.JNYD01000015_gene4557	1.529e-252	788.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4E0F3@85010|Pseudonocardiales	201174|Actinobacteria	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158351_k127_612475_1	1301098.PKB_1438	9.05e-45	175.0	COG0738@1|root,COG0738@2|Bacteria,1MVR9@1224|Proteobacteria,1RNEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	ybjJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158351_k127_615163_0	457425.XNR_3058	4.001e-64	233.0	COG0303@1|root,COG0303@2|Bacteria,2GP1B@201174|Actinobacteria	201174|Actinobacteria	H	molybdopterin	moaA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158351_k127_615163_1	2074.JNYD01000018_gene2733	2.083e-05	47.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria,4E4U8@85010|Pseudonocardiales	201174|Actinobacteria	H	MoaE protein	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158351_k127_615350_0	1223542.GM1_015_00530	2.369e-210	665.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4GADE@85026|Gordoniaceae	201174|Actinobacteria	F	AICARFT/IMPCHase bienzyme	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158351_k127_615350_1	1122182.KB903836_gene5121	8.845e-51	191.0	COG3238@1|root,COG3238@2|Bacteria,2IB1U@201174|Actinobacteria,4DBCE@85008|Micromonosporales	201174|Actinobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158351_k127_61606_0	1397278.AYMV01000007_gene323	1.025e-134	430.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FK99@85023|Microbacteriaceae	201174|Actinobacteria	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158351_k127_61606_1	1171373.PACID_32200	3.742e-08	61.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DQ4D@85009|Propionibacteriales	201174|Actinobacteria	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158351_k127_61679_3	469371.Tbis_3419	3.889e-57	201.0	COG1246@1|root,COG1246@2|Bacteria,2GJBT@201174|Actinobacteria,4E2QK@85010|Pseudonocardiales	201174|Actinobacteria	E	N-acetylglutamate synthase	argA	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158351_k127_61679_0	1206101.AZXC01000018_gene5394	0.0	1439.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158351_k127_61679_4	1435356.Y013_09575	2.593e-15	79.0	2EHMU@1|root,33BDI@2|Bacteria,2HM2W@201174|Actinobacteria,4G3KX@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
SRR25158351_k127_61679_2	1306174.JODP01000006_gene3376	1.659e-89	302.0	COG2890@1|root,COG2890@2|Bacteria,2I3EW@201174|Actinobacteria	201174|Actinobacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_61679_1	1463934.JOCF01000021_gene1701	5.521e-120	389.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158351_k127_620482_0	1348338.ADILRU_1594	7.48e-94	313.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FKZR@85023|Microbacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158351_k127_620482_1	1032480.MLP_15550	2.899e-64	227.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4DV5W@85009|Propionibacteriales	201174|Actinobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR25158351_k127_620482_2	1032480.MLP_15560	5.731e-41	153.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DPAN@85009|Propionibacteriales	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158351_k127_624891_0	67352.JODS01000030_gene1029	2.275e-170	540.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158351_k127_625326_1	469371.Tbis_1452	3.405e-84	286.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4E01I@85010|Pseudonocardiales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158351_k127_625326_0	1283283.ATXA01000003_gene1500	1.844e-202	636.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4ERSM@85013|Frankiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
SRR25158351_k127_630828_2	298654.FraEuI1c_1831	1.781e-28	116.0	arCOG05416@1|root,33310@2|Bacteria,2IQR4@201174|Actinobacteria,4EXJ0@85013|Frankiales	201174|Actinobacteria	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_630828_1	1048339.KB913029_gene4370	8.651e-31	125.0	2E9MI@1|root,333U6@2|Bacteria,2IMX9@201174|Actinobacteria,4ETA1@85013|Frankiales	201174|Actinobacteria	S	lycopene cyclase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_630828_0	1504319.GM45_0995	5.868e-42	157.0	COG1562@1|root,COG1562@2|Bacteria,2HFT6@201174|Actinobacteria,3UXMW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Squalene/phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
SRR25158351_k127_638699_1	1380347.JNII01000007_gene504	2.908e-146	468.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158351_k127_638699_0	717785.HYPMC_3602	1.709e-148	484.0	COG1457@1|root,COG1457@2|Bacteria	2|Bacteria	F	cytosine transport	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158351_k127_638699_2	1504319.GM45_0140	2.735e-105	355.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,3UWI7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158351_k127_638699_3	585531.HMPREF0063_12562	2.613e-67	232.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4DQT9@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0234 family	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158351_k127_638699_4	446470.Snas_5950	2.911e-29	121.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria,4EZPX@85014|Glycomycetales	201174|Actinobacteria	C	4Fe-4S dicluster domain	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158351_k127_638699_5	1440053.JOEI01000008_gene6268	1.356e-06	51.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158351_k127_642453_1	1121946.AUAX01000006_gene3575	1.446e-58	208.0	COG1120@1|root,COG1120@2|Bacteria,2IA4F@201174|Actinobacteria,4DA8F@85008|Micromonosporales	201174|Actinobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158351_k127_642453_0	479433.Caci_1835	1.032e-135	440.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158351_k127_649032_9	926569.ANT_22220	1.735e-45	170.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
SRR25158351_k127_649032_6	479431.Namu_4967	6.923e-91	310.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,4ERFU@85013|Frankiales	201174|Actinobacteria	P	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
SRR25158351_k127_649032_7	1121381.JNIV01000001_gene2856	2.288e-60	218.0	COG1834@1|root,COG1834@2|Bacteria	2|Bacteria	E	dimethylargininase activity	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158351_k127_649032_11	529884.Rhola_00002480	7.575e-12	78.0	COG4585@1|root,COG4585@2|Bacteria,2GWSQ@201174|Actinobacteria,4FQRQ@85023|Microbacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_649032_1	675635.Psed_3436	5.068e-165	528.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4E9P5@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD binding domain	menJ	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158351_k127_649032_5	313589.JNB_10774	3.033e-92	307.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4FF52@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158351_k127_649032_4	1504319.GM45_2305	8.035e-130	423.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,3UWJF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158351_k127_649032_0	1504319.GM45_2300	6.22e-234	733.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,3UWDV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158351_k127_649032_3	1504319.GM45_2295	3.201e-135	439.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,3UWIM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158351_k127_649032_2	1504319.GM45_2290	3.303e-158	508.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,3UW98@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158351_k127_649032_8	593907.Celgi_2515	1.293e-59	208.0	COG0295@1|root,COG0295@2|Bacteria,2IHP7@201174|Actinobacteria,4F1BD@85016|Cellulomonadaceae	201174|Actinobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158351_k127_649032_10	645127.ckrop_1388	3.706e-45	166.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,22KRN@1653|Corynebacteriaceae	201174|Actinobacteria	F	phosphorylase	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158351_k127_655310_5	369723.Strop_4317	1.003e-53	195.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4D93T@85008|Micromonosporales	201174|Actinobacteria	L	Nudix hydrolase	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158351_k127_655310_1	1137268.AZXF01000024_gene1158	2.395e-97	322.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4EG20@85012|Streptosporangiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158351_k127_655310_2	44060.JODL01000015_gene5271	3.743e-90	301.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158351_k127_655310_4	1380370.JIBA01000003_gene2689	1.11e-57	204.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4FGP9@85021|Intrasporangiaceae	201174|Actinobacteria	J	LysR family transcriptional regulator	yabJ	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158351_k127_655310_9	35754.JNYJ01000038_gene5045	1.079e-24	103.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4DFIW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158351_k127_655310_6	1463856.JOHY01000012_gene3231	3.101e-42	157.0	2CC1Y@1|root,32TCV@2|Bacteria,2IQEP@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	wblA	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158351_k127_655310_7	500153.JOEK01000001_gene4063	1.828e-40	155.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria	201174|Actinobacteria	S	GatB YqeY	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158351_k127_655310_3	479433.Caci_0659	4.983e-63	227.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158351_k127_655310_0	1123321.KB905819_gene5845	1.58e-119	393.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria	201174|Actinobacteria	E	May catalyze the transamination reaction in phenylalanine biosynthesis	pat	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158351_k127_655310_8	1504319.GM45_6175	1.33e-33	130.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,3UXSC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158351_k127_671109_1	1304865.JAGF01000001_gene2688	5.355e-85	291.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4F0GT@85016|Cellulomonadaceae	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158351_k127_671109_0	288705.RSal33209_0444	1.645e-137	441.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,1W80X@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158351_k127_67185_0	1122138.AQUZ01000016_gene212	7.096e-285	895.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4DPNM@85009|Propionibacteriales	201174|Actinobacteria	L	DNA Topoisomerase IV	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158351_k127_67185_2	1380354.JIAN01000006_gene687	9.532e-31	131.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4F1CN@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
SRR25158351_k127_67185_1	58123.JOFJ01000005_gene1456	9.654e-65	232.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4EG2I@85012|Streptosporangiales	201174|Actinobacteria	G	Inositol monophosphatase family	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158351_k127_67185_3	675635.Psed_4775	4.085e-08	55.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4E34J@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	gca	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
SRR25158351_k127_680284_0	479431.Namu_1926	5.076e-146	465.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4ES4G@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158351_k127_680284_2	263358.VAB18032_28211	4.975e-14	76.0	COG2329@1|root,COG2329@2|Bacteria,2GQZB@201174|Actinobacteria,4DEM3@85008|Micromonosporales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158351_k127_680284_3	479432.Sros_2344	2.617e-06	53.0	2C98I@1|root,33EGA@2|Bacteria,2IQRU@201174|Actinobacteria,4EKFZ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_680284_1	390989.JOEG01000017_gene6236	3.029e-40	154.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria,4DDCM@85008|Micromonosporales	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158351_k127_692998_1	1112204.GPOL_c20940	2.954e-51	188.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4GB4D@85026|Gordoniaceae	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_692998_0	471853.Bcav_2461	1.371e-60	211.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria	201174|Actinobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158351_k127_693894_0	479433.Caci_2378	1.028e-173	554.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158351_k127_694152_5	1504319.GM45_0910	7.825e-45	169.0	COG3201@1|root,COG3201@2|Bacteria	2|Bacteria	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
SRR25158351_k127_694152_6	1146883.BLASA_2427	5.215e-31	128.0	COG0572@1|root,COG0572@2|Bacteria,2HQC8@201174|Actinobacteria,4EWG1@85013|Frankiales	201174|Actinobacteria	F	Product type e enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Cytidylate_kin
SRR25158351_k127_694152_0	469371.Tbis_2890	0.0	1612.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DYC3@85010|Pseudonocardiales	201174|Actinobacteria	C	Dehydrogenase E1 component	kgd	-	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158351_k127_694152_7	1003195.SCAT_4115	1.265e-25	106.0	2E460@1|root,32Z20@2|Bacteria,2GQGS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_694152_1	479432.Sros_8289	5.294e-120	393.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4EGEB@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	adh3	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158351_k127_694152_8	1237500.ANBA01000007_gene2751	8.835e-05	48.0	COG0681@1|root,COG0681@2|Bacteria,2GQUN@201174|Actinobacteria,4EKK8@85012|Streptosporangiales	201174|Actinobacteria	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158351_k127_694152_2	1120950.KB892749_gene3304	4.502e-63	218.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4DQX0@85009|Propionibacteriales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158351_k127_694152_3	1123321.KB905814_gene1926	1.157e-52	191.0	COG1247@1|root,COG1247@2|Bacteria,2IHSU@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158351_k127_694152_4	1278078.G419_24687	2.639e-51	193.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4FUCI@85025|Nocardiaceae	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158351_k127_698182_1	1048339.KB913029_gene2909	5.811e-31	124.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4ERIC@85013|Frankiales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158351_k127_698182_0	1463864.JOGO01000029_gene3571	2.372e-62	221.0	COG1633@1|root,COG1633@2|Bacteria,2I2E1@201174|Actinobacteria	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
SRR25158351_k127_698182_3	1121017.AUFG01000003_gene3443	7.711e-16	79.0	2E3M2@1|root,32YJA@2|Bacteria,2HXUV@201174|Actinobacteria,4FHSG@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158351_k127_698182_4	1122917.KB899664_gene2946	5.511e-15	90.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,1VJJV@1239|Firmicutes,4HP9J@91061|Bacilli,274AH@186822|Paenibacillaceae	91061|Bacilli	MU	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,FIVAR,SLH
SRR25158351_k127_698182_2	1469557.JSWF01000017_gene2266	2.268e-20	108.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,HYR,PKD,P_proprotein,SprB
SRR25158351_k127_719866_0	1504319.GM45_6215	1.167e-130	425.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,3UWHW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158351_k127_721648_0	1504319.GM45_6205	5.414e-192	604.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,3UW89@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158351_k127_728426_0	1123024.AUII01000027_gene2661	1.418e-63	226.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4DXVE@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158351_k127_728426_1	1451261.AS96_14445	3.204e-21	97.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4FP2B@85023|Microbacteriaceae	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158351_k127_730513_7	479432.Sros_1689	1.212e-29	124.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4EFJ5@85012|Streptosporangiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158351_k127_730513_8	1120950.KB892745_gene2909	5.486e-28	115.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,4DS23@85009|Propionibacteriales	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_730513_3	994479.GL877878_gene231	9.554e-97	322.0	COG2945@1|root,COG2945@2|Bacteria,2GP8G@201174|Actinobacteria,4E06N@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase of the alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_6
SRR25158351_k127_730513_5	43354.JOIJ01000028_gene3451	2.408e-47	180.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4E2R5@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158351_k127_730513_9	1041826.FCOL_05220	4.01e-20	99.0	2E54J@1|root,32ZXH@2|Bacteria,4P2Q2@976|Bacteroidetes,1IDD8@117743|Flavobacteriia,2NY2A@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_730513_6	1120954.ATXE01000002_gene1099	1.072e-35	140.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4DQPV@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158351_k127_730513_2	28042.GU90_18290	1.009e-163	523.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DYM7@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158351_k127_730513_4	1306174.JODP01000018_gene4385	8.218e-79	273.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158351_k127_730513_0	1123320.KB889709_gene8400	0.0	1008.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158351_k127_730513_1	1206101.AZXC01000003_gene310	1.207e-246	777.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158351_k127_730513_10	91464.S7335_2437	6.1e-08	58.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1GZR8@1129|Synechococcus	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158351_k127_734233_2	67257.JODR01000015_gene5943	1.368e-10	63.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	hemY	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158351_k127_734233_1	1137269.AZWL01000009_gene3729	1.75e-101	338.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158351_k127_734233_0	1449976.KALB_1940	1.472e-183	588.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4E04X@85010|Pseudonocardiales	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158351_k127_735410_0	744985.HIMB59_00003530	1.261e-84	283.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,4BRBC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158351_k127_735410_4	498211.CJA_2489	1.522e-06	51.0	2EGPU@1|root,31UHU@2|Bacteria,1Q0YM@1224|Proteobacteria,1SE21@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_735410_3	744985.HIMB59_00003550	1.839e-16	84.0	2E3ZS@1|root,32YWP@2|Bacteria,1NAZV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_735410_1	1463936.JOJI01000042_gene605	2.232e-80	275.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh_2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158351_k127_735410_2	1210046.B277_13494	1.136e-27	114.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria	201174|Actinobacteria	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158351_k127_75257_2	1449357.JQLK01000001_gene2251	2.201e-21	94.0	COG3329@1|root,COG3329@2|Bacteria,1WJER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
SRR25158351_k127_75257_3	58123.JOFJ01000006_gene91	4.176e-09	60.0	295AS@1|root,2ZSNY@2|Bacteria,2HDA6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158351_k127_75257_0	1121366.KB892457_gene911	2.747e-86	292.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,22KKH@1653|Corynebacteriaceae	201174|Actinobacteria	J	ribosomal RNA large subunit methyltransferase J	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158351_k127_75257_1	479435.Kfla_5420	3.051e-44	167.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4DPDG@85009|Propionibacteriales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158351_k127_761874_0	931627.MycrhDRAFT_2921	4.309e-200	637.0	COG0247@1|root,COG3266@1|root,COG0247@2|Bacteria,COG3266@2|Bacteria,2GJ7M@201174|Actinobacteria,232WS@1762|Mycobacteriaceae	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158351_k127_761874_1	1120954.ATXE01000001_gene2049	1.423e-80	271.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DN90@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158351_k127_776883_0	66429.JOFL01000010_gene1115	3.556e-278	871.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158351_k127_776883_1	1380370.JIBA01000013_gene1535	6.579e-110	363.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4FEY1@85021|Intrasporangiaceae	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158351_k127_776883_2	313589.JNB_03425	8.122e-78	269.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4FG1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158351_k127_777408_1	1292020.H483_0108680	2.984e-55	195.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158351_k127_777408_0	1504319.GM45_2435	1.721e-64	233.0	COG0789@1|root,COG0789@2|Bacteria,2I8T8@201174|Actinobacteria,3UXIG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	litR	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158351_k127_777408_2	882082.SaccyDRAFT_0562	9.167e-38	145.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4E4SU@85010|Pseudonocardiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158351_k127_777408_3	1304865.JAGF01000001_gene2001	2.641e-34	133.0	COG1063@1|root,COG1063@2|Bacteria,2H2JG@201174|Actinobacteria	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158351_k127_78492_1	28444.JODQ01000004_gene6266	2.049e-54	195.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4EG1A@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158351_k127_78492_0	1463920.JOGB01000002_gene3209	6.572e-234	734.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria	201174|Actinobacteria	O	AAA ATPase forming ring-shaped complexes	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158351_k127_78566_2	452652.KSE_25750	1.14e-25	108.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,2M1BI@2063|Kitasatospora	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158351_k127_78566_1	1122611.KB903948_gene6735	4.4e-53	194.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,4EJPD@85012|Streptosporangiales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158351_k127_78566_0	479432.Sros_2283	0.0	1009.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4EGDX@85012|Streptosporangiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158351_k127_793491_1	469371.Tbis_1126	8.745e-51	182.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DXJ9@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158351_k127_793491_2	1385518.N798_15865	3.804e-37	146.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4FGQS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158351_k127_793491_0	367299.JOEE01000009_gene243	7.048e-181	571.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4FFS1@85021|Intrasporangiaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158351_k127_793491_4	397278.JOJN01000007_gene3409	2.767e-15	77.0	2AU8K@1|root,31JVT@2|Bacteria,2HZCZ@201174|Actinobacteria,4DS5N@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
SRR25158351_k127_793491_3	446470.Snas_4259	9.058e-22	98.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,4EYYA@85014|Glycomycetales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158351_k127_795743_0	1283287.KB822579_gene2200	4.441e-87	297.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4DNMH@85009|Propionibacteriales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158351_k127_795743_1	298655.KI912266_gene3659	3.777e-50	181.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4ERZF@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158351_k127_827391_5	1454010.JEOE01000006_gene2194	1.179e-36	140.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4F2MF@85016|Cellulomonadaceae	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158351_k127_827391_2	1122609.AUGT01000022_gene718	2.171e-82	283.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DNXK@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158351_k127_827391_1	1236902.ANAS01000025_gene375	4.136e-84	287.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4EGVA@85012|Streptosporangiales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158351_k127_827391_3	1123322.KB904681_gene4762	7.265e-75	263.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria	201174|Actinobacteria	J	PFAM phosphoesterase, RecJ domain protein	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158351_k127_827391_4	1122611.KB903982_gene3591	3.442e-45	167.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4EJ5K@85012|Streptosporangiales	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158351_k127_827391_0	351607.Acel_1515	6.785e-192	605.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4ERI2@85013|Frankiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158351_k127_837931_2	1122138.AQUZ01000094_gene5499	1.879e-17	85.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158351_k127_837931_0	211114.JOEF01000002_gene4539	1.25e-194	613.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4DYPJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158351_k127_837931_1	1440053.JOEI01000001_gene1551	1.208e-141	458.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	glgA	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158351_k127_866875_0	1298863.AUEP01000005_gene2409	5.972e-252	786.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4DPPB@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158351_k127_878894_4	1298863.AUEP01000005_gene2552	1.254e-16	90.0	COG5401@1|root,COG5401@2|Bacteria,2IQ3Y@201174|Actinobacteria,4DRIJ@85009|Propionibacteriales	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158351_k127_878894_2	1035308.AQYY01000001_gene1454	8.102e-47	177.0	COG5274@1|root,COG5274@2|Bacteria	2|Bacteria	C	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
SRR25158351_k127_878894_0	1504319.GM45_1900	4.313e-105	350.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,3UWC2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158351_k127_88897_1	888052.HMPREF9006_0194	5.086e-21	93.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4D4HM@85005|Actinomycetales	201174|Actinobacteria	FG	histidine triad	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158351_k127_88897_2	391037.Sare_1772	1.052e-10	72.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4D9YS@85008|Micromonosporales	201174|Actinobacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158351_k127_88897_0	1122130.AUHN01000008_gene1615	9.322e-32	130.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158351_k127_893168_4	1123320.KB889672_gene3754	0.00014	47.0	2EM5T@1|root,33EV2@2|Bacteria	2|Bacteria	S	Acyl-CoA carboxylase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_epsilon
SRR25158351_k127_893168_2	1463920.JOGB01000029_gene5567	2.081e-49	183.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
SRR25158351_k127_893168_0	479433.Caci_0809	1.264e-278	866.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158351_k127_893168_1	1123065.ATWL01000005_gene1235	8.304e-173	553.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158351_k127_893168_3	1123320.KB889686_gene602	4.047e-14	73.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158351_k127_895314_2	1504319.GM45_0450	4.069e-28	116.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,3UWVJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158351_k127_895314_1	404589.Anae109_4035	3.704e-78	268.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria	1224|Proteobacteria	GK	PFAM ROK family protein	ppgK	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158351_k127_895314_0	47763.JNZA01000035_gene2540	1.182e-141	453.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria	201174|Actinobacteria	E	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158351_k127_900736_1	367299.JOEE01000003_gene2705	2.967e-144	464.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4FFJ7@85021|Intrasporangiaceae	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158351_k127_900736_4	710686.Mycsm_01498	7.076e-26	113.0	COG1905@1|root,COG1905@2|Bacteria,2IM0C@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	1.6.5.3	ko:K00127,ko:K00334	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158351_k127_900736_3	2074.JNYD01000002_gene5791	1.023e-62	222.0	28I8Y@1|root,2Z8BR@2|Bacteria,2IJ1B@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
SRR25158351_k127_900736_0	367299.JOEE01000012_gene3263	2.938e-255	800.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2HE4H@201174|Actinobacteria,4FIQA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRR25158351_k127_900736_2	1184609.KILIM_048_00170	1.652e-102	338.0	COG1410@1|root,COG1410@2|Bacteria,2IC7C@201174|Actinobacteria	201174|Actinobacteria	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158351_k127_908412_1	1194972.MVAC_00845	3.861e-38	144.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,234C1@1762|Mycobacteriaceae	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158351_k127_908412_0	1172188.KB911821_gene1489	4.068e-82	281.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FF71@85021|Intrasporangiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158351_k127_911186_1	862751.SACTE_1349	1.694e-47	179.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR25158351_k127_911186_0	219305.MCAG_01085	2.005e-280	865.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4D8I1@85008|Micromonosporales	201174|Actinobacteria	O	assembly protein sufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158351_k127_911186_2	469371.Tbis_1971	2.268e-09	61.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4DXG3@85010|Pseudonocardiales	201174|Actinobacteria	O	TIGRFAM FeS assembly protein SufD	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158351_k127_919626_6	1504319.GM45_3030	1.843e-13	78.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
SRR25158351_k127_919626_3	1449353.JQMQ01000005_gene2550	1.324e-61	218.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,2NH0G@228398|Streptacidiphilus	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158351_k127_919626_0	1136417.AZWE01000007_gene1916	2.069e-205	646.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4DAAR@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158351_k127_919626_5	110319.CF8_3164	6.226e-16	83.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4DS5K@85009|Propionibacteriales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158351_k127_919626_2	479435.Kfla_5694	9.689e-68	233.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4DQUA@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158351_k127_919626_1	1123320.KB889574_gene5704	1.113e-106	353.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158351_k127_919626_4	1122130.AUHN01000005_gene2379	5.164e-40	150.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158351_k127_92751_0	1504319.GM45_5165	1.771e-114	381.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,3UWKE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158351_k127_929673_1	469371.Tbis_3419	6.668e-65	226.0	COG1246@1|root,COG1246@2|Bacteria,2GJBT@201174|Actinobacteria,4E2QK@85010|Pseudonocardiales	201174|Actinobacteria	E	N-acetylglutamate synthase	argA	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158351_k127_929673_0	994479.GL877879_gene4454	9.343e-190	601.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4DZ2T@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_931127_1	1122135.KB893141_gene79	4.399e-40	151.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158351_k127_931127_0	367299.JOEE01000012_gene3259	9.242e-231	722.0	COG5598@1|root,COG5598@2|Bacteria,2HSQ1@201174|Actinobacteria,4FIXA@85021|Intrasporangiaceae	201174|Actinobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
SRR25158351_k127_931127_2	367299.JOEE01000012_gene3260	1.203e-13	76.0	COG1414@1|root,COG1414@2|Bacteria,2IJV7@201174|Actinobacteria,4FJWZ@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158351_k127_935342_4	1033730.CAHG01000016_gene565	3.91e-57	203.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4DQAA@85009|Propionibacteriales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158351_k127_935342_1	1048339.KB913029_gene3939	1.581e-127	411.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4ES5T@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158351_k127_935342_3	1210046.B277_08285	1.133e-62	221.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4FG85@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158351_k127_935342_0	1048339.KB913029_gene3937	1.038e-159	506.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4ERGW@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158351_k127_935342_5	1121017.AUFG01000034_gene330	1.08e-27	119.0	COG1704@1|root,COG1704@2|Bacteria,2GK54@201174|Actinobacteria,4FGDG@85021|Intrasporangiaceae	201174|Actinobacteria	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
SRR25158351_k127_935342_2	1386089.N865_15275	1.216e-122	404.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4FEF1@85021|Intrasporangiaceae	201174|Actinobacteria	M	GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158351_k127_935342_6	1121360.AUAQ01000011_gene811	0.0001282	46.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,22JIJ@1653|Corynebacteriaceae	201174|Actinobacteria	M	Lauroyl myristoyl acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158351_k127_938783_0	928724.SacglDRAFT_03140	1.846e-172	547.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DXJ9@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158351_k127_938783_2	269800.Tfu_0815	2.471e-100	336.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4EFK3@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158351_k127_938783_3	67352.JODS01000025_gene3200	1.708e-67	239.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158351_k127_938783_1	1206720.BAFQ01000130_gene3202	3.186e-128	417.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4FWX6@85025|Nocardiaceae	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158351_k127_955190_3	591159.ACEZ01000169_gene3349	9.733e-98	323.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158351_k127_955190_7	1192034.CAP_9056	5.87e-36	144.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2Z0PW@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158351_k127_955190_2	1144310.PMI07_004774	3.728e-170	539.0	COG3938@1|root,COG3938@2|Bacteria,1N02K@1224|Proteobacteria,2VGM8@28211|Alphaproteobacteria,4B93W@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the proline racemase family	-	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0050346	-	-	-	-	-	-	-	-	-	-	Pro_racemase
SRR25158351_k127_955190_5	685727.REQ_16700	4.178e-78	273.0	COG3172@1|root,COG3172@2|Bacteria,2GXG6@201174|Actinobacteria,4FYT8@85025|Nocardiaceae	201174|Actinobacteria	H	AAA domain	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR25158351_k127_955190_1	1035308.AQYY01000001_gene3022	4.881e-187	587.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,260SZ@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158351_k127_955190_6	1463887.KL589967_gene6586	5.602e-66	229.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria	201174|Actinobacteria	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158351_k127_955190_0	1120950.KB892741_gene2671	4.833e-303	936.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DNJX@85009|Propionibacteriales	201174|Actinobacteria	E	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158351_k127_955190_4	479431.Namu_4080	7.213e-84	280.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4ERQZ@85013|Frankiales	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158351_k127_961050_0	1828.JOKB01000066_gene4681	2.468e-137	442.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FXI1@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158351_k127_968614_2	1504319.GM45_6265	6.186e-84	283.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,3UWJE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	ParB-like nuclease domain	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158351_k127_968614_0	1504319.GM45_6260	6.197e-145	464.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,3UW6Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPase MipZ	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158351_k127_968614_3	1504319.GM45_6255	5.391e-76	259.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,3UWVX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158351_k127_968614_4	1504319.GM45_6250	1.948e-63	220.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,3UWV4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158351_k127_968614_1	1504319.GM45_6245	1.647e-137	442.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,3UWKK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158351_k127_968614_5	1504319.GM45_6240	6.671e-36	139.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,3UWY8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158351_k127_968614_7	1504319.GM45_6235	1.584e-25	109.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158351_k127_968614_8	457425.XNR_3004	4.206e-15	75.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158351_k127_968614_6	1504319.GM45_6225	1.572e-33	132.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,3UW7I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158351_k127_972783_3	1144313.PMI10_03759	1.328e-12	79.0	COG2374@1|root,COG3209@1|root,COG4677@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG4677@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
SRR25158351_k127_972783_2	1121946.AUAX01000024_gene7588	6.946e-18	86.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_972783_0	1306174.JODP01000013_gene7456	3.899e-142	462.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158351_k127_972783_1	1121946.AUAX01000024_gene7587	2.129e-59	213.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4D95X@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158351_k127_975424_1	1122609.AUGT01000022_gene625	2.268e-59	208.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DN2T@85009|Propionibacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158351_k127_975424_0	253839.SSNG_05141	5.45e-103	346.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158351_k127_975424_2	35754.JNYJ01000013_gene1212	0.0006531	44.0	COG0303@1|root,COG0303@2|Bacteria,2GP1B@201174|Actinobacteria,4DBSX@85008|Micromonosporales	201174|Actinobacteria	H	Probable molybdopterin binding domain	moaA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158351_k127_982368_0	452652.KSE_19620	8.624e-207	658.0	COG0804@1|root,COG0804@2|Bacteria,2GM7X@201174|Actinobacteria,2M0XX@2063|Kitasatospora	201174|Actinobacteria	E	Urease alpha-subunit, N-terminal domain	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
SRR25158351_k127_982368_1	1003195.SCAT_4357	7.326e-58	208.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,2IKNA@201174|Actinobacteria	201174|Actinobacteria	E	belongs to the urease gamma subunit family	ureAB	-	3.5.1.5	ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
SRR25158351_k127_98626_1	1184607.AUCHE_09_00230	2.683e-26	114.0	COG0847@1|root,COG0847@2|Bacteria,2GJZ0@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DUF2510,Lsr2,RNase_T
SRR25158351_k127_98626_0	253839.SSNG_00156	3.839e-71	246.0	2DKWQ@1|root,30MQE@2|Bacteria,2I3CS@201174|Actinobacteria	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158351_k127_995614_1	1089455.MOPEL_130_02260	4.206e-15	75.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4F6PB@85018|Dermatophilaceae	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158351_k127_995614_0	1120950.KB892708_gene4284	9.06e-118	386.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DP1N@85009|Propionibacteriales	201174|Actinobacteria	J	Histidine--tRNA ligase	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
## 1324 queries scanned
## Total time (seconds): 22.64232873916626
## Rate: 58.47 q/s