## Sun Dec 14 20:51:08 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158357_bin.18.fa -m mmseqs --itype genome -o SRR25158357_bin.18 --output_dir /data/result/bins/wyx/egg/SRR25158357_bin.18 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158357_k127_1002434_7	452659.RrIowa_0183	8.664e-13	69.0	COG0419@1|root,COG3704@1|root,COG0419@2|Bacteria,COG3704@2|Bacteria,1NIX6@1224|Proteobacteria,2UK4E@28211|Alphaproteobacteria,47F7M@766|Rickettsiales	766|Rickettsiales	U	type IV secretion system protein	-	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158357_k127_1002434_2	336407.RBE_1262	1.266e-212	701.0	COG3704@1|root,COG3704@2|Bacteria,1Q7AD@1224|Proteobacteria,2VDEX@28211|Alphaproteobacteria,47G55@766|Rickettsiales	766|Rickettsiales	U	COG3704 Type IV secretory pathway, VirB6 components	virB6-4	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158357_k127_1002434_1	336407.RBE_1263	4.224e-233	762.0	COG3704@1|root,COG3704@2|Bacteria,1NP3X@1224|Proteobacteria,2UN3T@28211|Alphaproteobacteria,47FB9@766|Rickettsiales	766|Rickettsiales	U	COG3704 Type IV secretory pathway, VirB6 components	virB6-3	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158357_k127_1002434_3	315456.RF_0090	1.268e-184	600.0	COG3704@1|root,COG3704@2|Bacteria,1N1KD@1224|Proteobacteria,2UDXI@28211|Alphaproteobacteria,47FIS@766|Rickettsiales	766|Rickettsiales	U	Type IV secretory pathway, VirB6 components	virB6	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158357_k127_1002434_4	1144888.CM001467_gene1572	6.673e-149	494.0	COG3704@1|root,COG3704@2|Bacteria,1N1KD@1224|Proteobacteria,2UDXI@28211|Alphaproteobacteria,47G3H@766|Rickettsiales	766|Rickettsiales	U	COG3704 Type IV secretory pathway, VirB6 components	virB6-1	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158357_k127_1002434_5	336407.RBE_1265	9.647e-102	342.0	COG3704@1|root,COG3704@2|Bacteria,1N1KD@1224|Proteobacteria,2UDXI@28211|Alphaproteobacteria,47G3H@766|Rickettsiales	766|Rickettsiales	U	COG3704 Type IV secretory pathway, VirB6 components	virB6-1	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
SRR25158357_k127_1002434_0	334545.CCMG01000014_gene1058	0.0	1259.0	COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,47F23@766|Rickettsiales	766|Rickettsiales	U	type IV secretion system protein	virB4-1	-	-	ko:K03199	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagE_TrbE_VirB
SRR25158357_k127_1002434_6	293614.A1C_00780	1.199e-30	123.0	COG3702@1|root,COG3702@2|Bacteria,1NFFQ@1224|Proteobacteria,2UFJU@28211|Alphaproteobacteria,47FKA@766|Rickettsiales	766|Rickettsiales	U	Type IV secretory pathway, VirB3 components	virB3	-	-	ko:K03198	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	VirB3
SRR25158357_k127_1018255_10	272951.rsib_orf1383	4.112e-15	77.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	ihfB	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K03530,ko:K05788	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding,Ppx-GppA
SRR25158357_k127_1018255_1	315456.RF_0766	2.938e-97	326.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,47F8X@766|Rickettsiales	766|Rickettsiales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158357_k127_1018255_6	272951.rsib_orf103	1.841e-60	212.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,47FD9@766|Rickettsiales	766|Rickettsiales	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158357_k127_1018255_4	391896.A1I_04805	1.557e-80	278.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,47F5V@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158357_k127_1018255_2	1105110.MC5_04885	7.636e-91	307.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,47FAZ@766|Rickettsiales	766|Rickettsiales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158357_k127_1018255_3	334545.CCMG01000002_gene49	3.553e-83	281.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,47FD8@766|Rickettsiales	766|Rickettsiales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158357_k127_1018255_0	391896.A1I_04825	8.774e-127	419.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,47F4I@766|Rickettsiales	766|Rickettsiales	T	COG0642 Signal transduction histidine kinase	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158357_k127_1018255_5	1144888.CM001467_gene1055	9.825e-76	260.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,47F67@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158357_k127_1018255_7	334545.CCMG01000002_gene46	4.876e-54	197.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,47FFH@766|Rickettsiales	766|Rickettsiales	I	COG0575 CDP-diglyceride synthetase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158357_k127_1018255_8	336407.RBE_0747	3.75e-20	93.0	COG2919@1|root,COG2919@2|Bacteria,1Q75Y@1224|Proteobacteria,2VDAB@28211|Alphaproteobacteria,47FSI@766|Rickettsiales	766|Rickettsiales	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158357_k127_1018255_9	391896.A1I_04845	1.014e-19	89.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,47F54@766|Rickettsiales	766|Rickettsiales	J	3'-5' exonuclease	rnd2	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
SRR25158357_k127_1034521_3	521000.PROVRETT_09833	6.967e-103	340.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,3Z9TG@586|Providencia	1236|Gammaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158357_k127_1034521_0	391613.RTM1035_01560	3.824e-113	374.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,46NX8@74030|Roseovarius	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158357_k127_1034521_4	1040987.AZUY01000011_gene4979	3.494e-93	318.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,43N46@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158357_k127_1034521_2	1040987.AZUY01000011_gene4980	9.49e-107	354.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K20534	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRR25158357_k127_1034521_1	768671.ThimaDRAFT_1568	1.424e-109	362.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,1RXAQ@1236|Gammaproteobacteria,1WXX9@135613|Chromatiales	135613|Chromatiales	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
SRR25158357_k127_1034521_5	1408444.JHYC01000008_gene1377	6.393e-16	85.0	COG1835@1|root,COG1835@2|Bacteria,1NWQN@1224|Proteobacteria	1224|Proteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158357_k127_1037132_1	336407.RBE_0700	6.873e-198	629.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,47F1F@766|Rickettsiales	766|Rickettsiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158357_k127_1037132_7	1144888.CM001467_gene693	9.785e-37	143.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,47FKT@766|Rickettsiales	766|Rickettsiales	U	The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF- YajC-YidC subcomplex facilitates these functions	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158357_k127_1037132_0	334545.CCMG01000018_gene1473	5.03e-222	703.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47ET8@766|Rickettsiales	766|Rickettsiales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	msbA1	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_1037132_3	357244.OTBS_0551	2.87e-57	207.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,47FIW@766|Rickettsiales	766|Rickettsiales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158357_k127_1037132_8	257363.RT0091	1.952e-35	139.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,47FKY@766|Rickettsiales	766|Rickettsiales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158357_k127_1037132_10	293613.A1E_00190	2.268e-27	114.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,47FM3@766|Rickettsiales	766|Rickettsiales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158357_k127_1037132_9	315456.RF_0141	3.068e-35	141.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,47FG1@766|Rickettsiales	766|Rickettsiales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158357_k127_1037132_13	1399147.P618_200511	8.746e-07	52.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_Tnp_IS630
SRR25158357_k127_1037132_12	257363.RT0625	1.38e-18	91.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,47FP8@766|Rickettsiales	766|Rickettsiales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158357_k127_1037132_6	272951.rsib_orf1116	2.334e-51	185.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,47FDE@766|Rickettsiales	766|Rickettsiales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158357_k127_1037132_2	452659.RrIowa_1173	8.01e-146	469.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,47F1V@766|Rickettsiales	766|Rickettsiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158357_k127_1037132_5	336407.RBE_1039	1.114e-52	188.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,47FJJ@766|Rickettsiales	766|Rickettsiales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158357_k127_1037132_4	293613.A1E_04260	8.123e-53	188.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,47FEA@766|Rickettsiales	766|Rickettsiales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158357_k127_1037132_11	272951.rsib_orf1112	9.24e-25	106.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,47FHZ@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158357_k127_1049638_2	1282876.BAOK01000001_gene3603	2.99e-88	297.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,4BPAF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158357_k127_1049638_3	336407.RBE_0256	1.46e-77	272.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,47FEX@766|Rickettsiales	766|Rickettsiales	J	ribosomal large subunit pseudouridine synthase	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158357_k127_1049638_0	315456.RF_1024	1.736e-99	335.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,47F5S@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158357_k127_1049638_1	336407.RBE_0717	2.822e-97	328.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,47F6Z@766|Rickettsiales	766|Rickettsiales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158357_k127_1049638_4	452659.RrIowa_0858	1.195e-47	188.0	29ECA@1|root,301A9@2|Bacteria,1PSGB@1224|Proteobacteria,2V4N8@28211|Alphaproteobacteria,47GNF@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1049638_6	1144888.CM001467_gene931	2.121e-22	100.0	29ECA@1|root,301A9@2|Bacteria,1PSGB@1224|Proteobacteria,2V4N8@28211|Alphaproteobacteria,47GNF@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1049638_5	257363.RT0464	1.363e-31	124.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47FWA@766|Rickettsiales	766|Rickettsiales	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TLC
SRR25158357_k127_1059542_9	336407.RBE_0726	3.035e-42	163.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria	1224|Proteobacteria	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
SRR25158357_k127_1059542_2	293614.A1C_05240	4.679e-178	567.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,47ETV@766|Rickettsiales	766|Rickettsiales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158357_k127_1059542_6	315456.RF_0504	3.979e-83	282.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,47F8S@766|Rickettsiales	766|Rickettsiales	U	Biopolymer transport	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
SRR25158357_k127_1059542_8	391896.A1I_06465	1.065e-45	169.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,47FDJ@766|Rickettsiales	766|Rickettsiales	U	COG0848 Biopolymer transport protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
SRR25158357_k127_1059542_11	391896.A1I_06460	1.18e-30	131.0	COG3266@1|root,COG3266@2|Bacteria,1QVTV@1224|Proteobacteria,2UF2Z@28211|Alphaproteobacteria,47FJZ@766|Rickettsiales	766|Rickettsiales	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1059542_3	391896.A1I_06455	2.541e-158	510.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,47F05@766|Rickettsiales	766|Rickettsiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158357_k127_1059542_4	272951.rsib_orf646	5.366e-141	450.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,47EX7@766|Rickettsiales	766|Rickettsiales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_17,Fer4_8
SRR25158357_k127_1059542_0	272951.rsib_orf540	1.228e-319	985.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,47EUN@766|Rickettsiales	766|Rickettsiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158357_k127_1059542_12	336407.RBE_1167	6.107e-25	108.0	COG2142@1|root,COG2142@2|Bacteria,1Q3QW@1224|Proteobacteria,2VAE5@28211|Alphaproteobacteria,47FT2@766|Rickettsiales	766|Rickettsiales	C	Succinate dehydrogenase hydrophobic	sdhD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158357_k127_1059542_10	1144888.CM001467_gene1546	1.99e-32	130.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,47FMW@766|Rickettsiales	766|Rickettsiales	C	Succinate dehydrogenase, cytochrome b556 subunit	sdhC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158357_k127_1059542_7	391896.A1I_04425	1.998e-58	211.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,47FBZ@766|Rickettsiales	766|Rickettsiales	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158357_k127_1059542_5	336407.RBE_0625	2.564e-103	348.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,47F81@766|Rickettsiales	766|Rickettsiales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158357_k127_1059542_13	391896.A1I_01655	1.058e-18	92.0	COG1863@1|root,COG1863@2|Bacteria,1PDJ3@1224|Proteobacteria,2UDVY@28211|Alphaproteobacteria,47FT1@766|Rickettsiales	766|Rickettsiales	P	Na H antiporter	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
SRR25158357_k127_1059542_1	293614.A1C_01105	1.115e-211	670.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,47F4G@766|Rickettsiales	766|Rickettsiales	EGP	the major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SRR25158357_k127_109909_5	391896.A1I_04795	1.69e-55	205.0	COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,47FI8@766|Rickettsiales	766|Rickettsiales	O	disulfide	dsbA	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
SRR25158357_k127_109909_6	1121949.AQXT01000002_gene1960	2.852e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43YU8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Recombinase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158357_k127_109909_4	272947.RP847	8.819e-64	225.0	COG0220@1|root,COG2890@1|root,COG0220@2|Bacteria,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,47FB8@766|Rickettsiales	766|Rickettsiales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31,Methyltransf_4
SRR25158357_k127_109909_2	257363.RT0318	3.278e-83	280.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,47F5T@766|Rickettsiales	766|Rickettsiales	O	C-terminal domain of 1-Cys peroxiredoxin	tdpX1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158357_k127_109909_1	357244.OTBS_1123	2.267e-111	371.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,47EX0@766|Rickettsiales	766|Rickettsiales	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158357_k127_109909_0	293614.A1C_02440	0.0	1040.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,47EW5@766|Rickettsiales	766|Rickettsiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
SRR25158357_k127_109909_3	336407.RBE_0230	2.913e-65	225.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,47F38@766|Rickettsiales	766|Rickettsiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158357_k127_1106833_6	1158756.AQXQ01000012_gene1436	2.923e-13	78.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1WYZ4@135613|Chromatiales	135613|Chromatiales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRR25158357_k127_1106833_0	315456.RF_0214	1.395e-175	567.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47EVM@766|Rickettsiales	766|Rickettsiales	V	Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation (By similarity)	msbA2	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_1106833_5	334545.CCMG01000017_gene1370	1.648e-27	114.0	COG1965@1|root,COG1965@2|Bacteria	2|Bacteria	P	Belongs to the frataxin family	cyaY	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564	1.16.3.1	ko:K06202,ko:K19054	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000,ko03029	-	-	iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108	Frataxin_Cyay
SRR25158357_k127_1106833_4	391896.A1I_07085	2.416e-29	121.0	COG5389@1|root,COG5389@2|Bacteria,1N82D@1224|Proteobacteria,2UAUA@28211|Alphaproteobacteria,47FSR@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158357_k127_1106833_3	391896.A1I_07090	4.242e-88	301.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2TTW6@28211|Alphaproteobacteria,47FCS@766|Rickettsiales	766|Rickettsiales	M	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	mraY2	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158357_k127_1106833_2	391896.A1I_07095	9.359e-89	299.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,47FB2@766|Rickettsiales	766|Rickettsiales	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158357_k127_1106833_1	1105110.MC5_01405	6.881e-138	441.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,47EVR@766|Rickettsiales	766|Rickettsiales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158357_k127_1127998_5	336407.RBE_1141	3.201e-33	133.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,47FII@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158357_k127_1127998_3	391896.A1I_02935	1.741e-70	244.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,47FCU@766|Rickettsiales	766|Rickettsiales	J	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158357_k127_1127998_2	334545.CCMG01000018_gene1463	1.168e-120	402.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,2U4CI@28211|Alphaproteobacteria,47FEW@766|Rickettsiales	766|Rickettsiales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRR25158357_k127_1127998_4	334545.CCMG01000018_gene1464	7.133e-58	207.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,47FDG@766|Rickettsiales	766|Rickettsiales	F	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158357_k127_1127998_0	1144888.CM001467_gene1125	7.133e-183	581.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,47EZQ@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158357_k127_1127998_1	257363.RT0694	4.277e-128	420.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,47EU5@766|Rickettsiales	766|Rickettsiales	M	Lipoprotein releasing system transmembrane protein	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158357_k127_1130374_9	391896.A1I_07010	8.217e-09	56.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,47F3M@766|Rickettsiales	766|Rickettsiales	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158357_k127_1130374_0	293613.A1E_03265	1.874e-274	865.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,47F2J@766|Rickettsiales	766|Rickettsiales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158357_k127_1130374_1	315456.RF_0647	8.216e-154	493.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,47EY7@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158357_k127_1130374_7	315456.RF_1169	4.019e-85	292.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,47F5F@766|Rickettsiales	766|Rickettsiales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158357_k127_1130374_3	452659.RrIowa_0205	1.189e-125	411.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,47EUY@766|Rickettsiales	766|Rickettsiales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRR25158357_k127_1130374_4	293613.A1E_00625	6.26e-105	347.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,47F07@766|Rickettsiales	766|Rickettsiales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
SRR25158357_k127_1130374_2	315456.RF_1166	3.228e-126	419.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,47F2S@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S1C family	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158357_k127_1130374_5	391896.A1I_01435	3.476e-100	334.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2TUB5@28211|Alphaproteobacteria,47F5M@766|Rickettsiales	766|Rickettsiales	S	Rhodanese Homology Domain	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
SRR25158357_k127_1130374_8	439493.PB7211_1191	6.662e-09	64.0	COG0745@1|root,COG0745@2|Bacteria	439493.PB7211_1191|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1130374_6	272951.rsib_orf41	7.308e-91	308.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,47FAP@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158357_k127_113064_1	981384.AEYW01000012_gene943	8.2e-172	548.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria,4NASD@97050|Ruegeria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	MA20_40290	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
SRR25158357_k127_113064_0	391896.A1I_00340	0.0	1043.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,47F0I@766|Rickettsiales	766|Rickettsiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158357_k127_113064_2	856793.MICA_2036	6.654e-75	285.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,4BQ67@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158357_k127_1130817_3	244582.JQAK01000001_gene1541	1.49e-21	100.0	COG0494@1|root,COG0494@2|Bacteria,1NWIQ@1224|Proteobacteria,2US7U@28211|Alphaproteobacteria,47FS7@766|Rickettsiales	766|Rickettsiales	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1130817_4	1190603.AJYD01000008_gene2154	3.64e-06	58.0	COG5309@1|root,COG5309@2|Bacteria,1MWJJ@1224|Proteobacteria,1SZ1N@1236|Gammaproteobacteria,1Y09H@135623|Vibrionales	135623|Vibrionales	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
SRR25158357_k127_1130817_1	985867.AEWF01000001_gene2026	3.955e-59	209.0	COG2964@1|root,COG2964@2|Bacteria,1RBFW@1224|Proteobacteria,2U5B8@28211|Alphaproteobacteria,47GGD@766|Rickettsiales	766|Rickettsiales	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
SRR25158357_k127_1130817_5	244582.JQAK01000001_gene1006	0.0003855	43.0	COG2964@1|root,COG2964@2|Bacteria,1RBFW@1224|Proteobacteria,2U5B8@28211|Alphaproteobacteria,47GGD@766|Rickettsiales	766|Rickettsiales	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
SRR25158357_k127_1130817_0	985867.AEWF01000001_gene2025	1.027e-177	563.0	COG0436@1|root,COG0436@2|Bacteria,1PEQR@1224|Proteobacteria,2V7WB@28211|Alphaproteobacteria,47GBS@766|Rickettsiales	766|Rickettsiales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158357_k127_1130817_2	1144888.CM001467_gene1529	3.563e-34	132.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,47FHD@766|Rickettsiales	766|Rickettsiales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158357_k127_1137353_0	856793.MICA_1415	2.209e-132	434.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,4BP8P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	DEAD-like helicases superfamily	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158357_k127_1137353_1	1278306.KB906906_gene371	5.798e-81	274.0	COG0036@1|root,COG0036@2|Bacteria,379G5@32066|Fusobacteria	32066|Fusobacteria	G	Ribulose-phosphate 3-epimerase	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158357_k127_1159592_5	357244.OTBS_0921	1.205e-96	321.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,47F5J@766|Rickettsiales	766|Rickettsiales	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
SRR25158357_k127_1159592_8	293614.A1C_05345	7.095e-77	267.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,47FA7@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179,ko:K06125	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117,M00128	R05000,R05615,R05616,R07273	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158357_k127_1159592_0	334545.CCMG01000008_gene589	0.0	1144.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,47ETH@766|Rickettsiales	766|Rickettsiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158357_k127_1159592_3	244582.JQAK01000004_gene406	6.695e-120	395.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,2UTUU@28211|Alphaproteobacteria,47FX2@766|Rickettsiales	766|Rickettsiales	E	Branched-chain amino acid transport protein	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
SRR25158357_k127_1159592_7	272951.rsib_orf235	3.278e-83	280.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,47F8N@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158357_k127_1159592_6	336407.RBE_0534	2.748e-90	304.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,47FF5@766|Rickettsiales	766|Rickettsiales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158357_k127_1159592_9	434131.NRI_0201	3.516e-35	142.0	COG3932@1|root,COG3932@2|Bacteria,1MZD5@1224|Proteobacteria,2U77X@28211|Alphaproteobacteria,47GF8@766|Rickettsiales	766|Rickettsiales	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
SRR25158357_k127_1159592_2	1105110.MC5_06500	4.904e-134	439.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,47EVF@766|Rickettsiales	766|Rickettsiales	S	Belongs to the peptidase M16 family	mpp	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158357_k127_1159592_4	336407.RBE_0651	2.443e-107	357.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,2TVC0@28211|Alphaproteobacteria,47F9U@766|Rickettsiales	766|Rickettsiales	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158357_k127_1159592_1	336407.RBE_0533	8.943e-152	490.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,47ETM@766|Rickettsiales	766|Rickettsiales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158357_k127_1210289_2	1034943.BN1094_00559	3.496e-68	246.0	COG1301@1|root,COG1301@2|Bacteria,1R3SN@1224|Proteobacteria,1RN3B@1236|Gammaproteobacteria,1JE5D@118969|Legionellales	118969|Legionellales	U	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158357_k127_1210289_1	86106.I862_00070	3.608e-72	249.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,47F9X@766|Rickettsiales	766|Rickettsiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158357_k127_1210289_0	391896.A1I_06065	2.019e-72	261.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1232315_2	315456.RF_1007	5.351e-109	357.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,47EWJ@766|Rickettsiales	766|Rickettsiales	C	Cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
SRR25158357_k127_1232315_0	315456.RF_1009	8.06e-226	704.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,47EXV@766|Rickettsiales	766|Rickettsiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
SRR25158357_k127_1232315_3	391896.A1I_05275	8.369e-84	280.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,47F5K@766|Rickettsiales	766|Rickettsiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
SRR25158357_k127_1232315_5	315456.RF_1012	5.656e-46	173.0	2AEME@1|root,314HB@2|Bacteria,1PU6R@1224|Proteobacteria,2V5YQ@28211|Alphaproteobacteria,47GFH@766|Rickettsiales	766|Rickettsiales	S	CcmB protein	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158357_k127_1232315_4	391896.A1I_07490	1.113e-64	227.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,47FJF@766|Rickettsiales	766|Rickettsiales	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158357_k127_1232315_1	1144888.CM001467_gene313	2.89e-140	451.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,47EVS@766|Rickettsiales	766|Rickettsiales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158357_k127_1259167_0	357244.OTBS_0269	2.013e-174	559.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,47F0M@766|Rickettsiales	766|Rickettsiales	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
SRR25158357_k127_1259167_2	856793.MICA_158	1.958e-85	299.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,4BPC5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158357_k127_1259167_7	1105110.MC5_00795	5.483e-36	155.0	COG3064@1|root,COG3468@1|root,COG3064@2|Bacteria,COG3468@2|Bacteria,1R7WR@1224|Proteobacteria,2TZH2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	MU	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
SRR25158357_k127_1259167_8	1370122.JHXQ01000003_gene1136	4.788e-09	59.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,4B75N@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158357_k127_1259167_1	315456.RF_0619	7.659e-120	392.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TQZP@28211|Alphaproteobacteria,47EZ0@766|Rickettsiales	766|Rickettsiales	OU	COG0616 Periplasmic serine proteases (ClpP class)	sppA1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S49
SRR25158357_k127_1259167_4	334545.CCMG01000018_gene1484	1.68e-43	168.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,47FKC@766|Rickettsiales	766|Rickettsiales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158357_k127_1259167_6	1537915.JU57_04460	9.523e-37	148.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,42NCD@68525|delta/epsilon subdivisions,2YRI9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158357_k127_1259167_5	376619.FTL_1883	6.356e-39	157.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,1RQZU@1236|Gammaproteobacteria,4609N@72273|Thiotrichales	72273|Thiotrichales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158357_k127_1259167_3	334545.CCMG01000008_gene640	2.089e-53	198.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,47GFJ@766|Rickettsiales	766|Rickettsiales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158357_k127_1265303_7	323098.Nwi_1094	8.814e-11	69.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,3JSQ3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158357_k127_1265303_3	336407.RBE_1105	1.629e-45	170.0	COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria,47FI6@766|Rickettsiales	766|Rickettsiales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
SRR25158357_k127_1265303_4	257363.RT0358	2.03e-24	108.0	COG1495@1|root,COG1495@2|Bacteria,1Q429@1224|Proteobacteria,2VAE2@28211|Alphaproteobacteria,47FRB@766|Rickettsiales	766|Rickettsiales	C	Disulfide bond formation protein, DsbB	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
SRR25158357_k127_1265303_0	315456.RF_0582	3.533e-253	789.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,47ESY@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158357_k127_1265303_6	658659.HMPREF0983_04096	2.51e-15	80.0	COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,3VUD1@526524|Erysipelotrichia	526524|Erysipelotrichia	S	phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
SRR25158357_k127_1265303_1	336407.RBE_0756	9.929e-146	478.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,2TR9F@28211|Alphaproteobacteria,47F3U@766|Rickettsiales	766|Rickettsiales	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
SRR25158357_k127_1265303_2	315456.RF_1033	2.521e-135	442.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,47F5Y@766|Rickettsiales	766|Rickettsiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158357_k127_1265303_5	5722.XP_001583286.1	7.24e-18	94.0	COG0666@1|root,KOG4412@2759|Eukaryota	2759|Eukaryota	L	proteasome regulatory particle assembly	-	-	-	ko:K15503,ko:K15504	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
SRR25158357_k127_1287330_1	1122962.AULH01000001_gene1494	1.561e-136	439.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,36XPS@31993|Methylocystaceae	28211|Alphaproteobacteria	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158357_k127_1287330_0	452659.RrIowa_0289	1.337e-157	512.0	COG0265@1|root,COG0265@2|Bacteria,1RBDX@1224|Proteobacteria,2U6E8@28211|Alphaproteobacteria,47F6D@766|Rickettsiales	766|Rickettsiales	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158357_k127_1287330_3	1088869.GMO_06370	1.884e-55	197.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,2JRR3@204441|Rhodospirillales	204441|Rhodospirillales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158357_k127_1287330_2	272951.rsib_orf629	2.616e-84	282.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,47F1A@766|Rickettsiales	766|Rickettsiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158357_k127_1327996_2	331869.BAL199_05789	7.061e-59	220.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,4BP61@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase family M48	MA20_29180	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
SRR25158357_k127_1327996_3	478749.BRYFOR_06004	2.745e-41	159.0	COG2843@1|root,COG2843@2|Bacteria,1V20N@1239|Firmicutes,24AI2@186801|Clostridia	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158357_k127_1327996_0	315456.RF_0990	4.434e-162	524.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria,47F71@766|Rickettsiales	766|Rickettsiales	T	signal transduction histidine kinase	barA	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158357_k127_1327996_4	334545.CCMG01000015_gene1231	4.675e-31	132.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,47FM5@766|Rickettsiales	766|Rickettsiales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6
SRR25158357_k127_1327996_5	293614.A1C_01705	1.539e-29	126.0	2A271@1|root,30QHP@2|Bacteria,1QBTC@1224|Proteobacteria,2VEEQ@28211|Alphaproteobacteria,47GJD@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF2659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2659
SRR25158357_k127_1327996_1	272947.RP232	1.559e-89	309.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,47FF2@766|Rickettsiales	766|Rickettsiales	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158357_k127_136906_15	336407.RBE_1184	1.262e-08	56.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,47F5C@766|Rickettsiales	766|Rickettsiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158357_k127_136906_9	336407.RBE_0972	2.717e-74	254.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,47FA9@766|Rickettsiales	766|Rickettsiales	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158357_k127_136906_12	272951.rsib_orf380	2.411e-32	135.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,47F9T@766|Rickettsiales	766|Rickettsiales	G	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158357_k127_136906_13	334545.CCMG01000015_gene1245	4.652e-29	119.0	2E34P@1|root,32Y4S@2|Bacteria,1NF64@1224|Proteobacteria,2UGC0@28211|Alphaproteobacteria,47FPE@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF2610)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2610
SRR25158357_k127_136906_0	334545.CCMG01000002_gene42	0.0	1153.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,47EWT@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158357_k127_136906_11	293613.A1E_03255	7.332e-47	173.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria,47FM2@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
SRR25158357_k127_136906_7	244582.JQAK01000001_gene829	2.039e-79	269.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria,47FXT@766|Rickettsiales	766|Rickettsiales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158357_k127_136906_5	244582.JQAK01000001_gene829	2.578e-88	296.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria,47FXT@766|Rickettsiales	766|Rickettsiales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158357_k127_136906_8	336407.RBE_0321	6.957e-78	266.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,47F6K@766|Rickettsiales	766|Rickettsiales	J	COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158357_k127_136906_10	334545.CCMG01000007_gene294	3.898e-53	192.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,47FGC@766|Rickettsiales	766|Rickettsiales	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158357_k127_136906_1	334545.CCMG01000007_gene295	3.816e-187	593.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,47F1T@766|Rickettsiales	766|Rickettsiales	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
SRR25158357_k127_136906_14	1105367.CG50_04175	3.309e-23	100.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158357_k127_136906_6	336407.RBE_1174	1.131e-82	285.0	COG0617@1|root,COG3660@1|root,COG0617@2|Bacteria,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,2TQWV@28211|Alphaproteobacteria,47FAD@766|Rickettsiales	766|Rickettsiales	M	nucleoside-diphosphate-sugar epimerase	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
SRR25158357_k127_136906_2	1232410.KI421414_gene2870	4.806e-171	548.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,43T96@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158357_k127_136906_4	1122164.JHWF01000011_gene2465	9.152e-98	336.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,1JCV5@118969|Legionellales	118969|Legionellales	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158357_k127_136906_3	452471.Aasi_0674	4.37e-111	375.0	COG1132@1|root,COG1132@2|Bacteria,4NZYU@976|Bacteroidetes,47XHN@768503|Cytophagia	976|Bacteroidetes	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_136906_16	1230343.CANP01000031_gene2517	3.13e-07	56.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1JCHU@118969|Legionellales	118969|Legionellales	V	to multidrug resistance ABC transporter ATP-binding protein	abcT	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_1391333_0	452659.RrIowa_0492	3.491e-186	592.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,47F3G@766|Rickettsiales	766|Rickettsiales	E	COG0531 Amino acid transporters	atrC1	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158357_k127_1391333_2	272951.rsib_orf292	2.561e-164	524.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,47F3C@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158357_k127_1391333_1	357244.OTBS_1416	2.855e-182	586.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,47EXM@766|Rickettsiales	766|Rickettsiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158357_k127_1391333_3	315456.RF_0085	1.292e-57	207.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,47FFE@766|Rickettsiales	766|Rickettsiales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158357_k127_1413412_4	244581.IM40_06390	7.671e-05	46.0	2EN6R@1|root,33FUM@2|Bacteria,1P9EZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1413412_0	1528098.NOVO_02740	2.642e-66	233.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,47FAV@766|Rickettsiales	766|Rickettsiales	S	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158357_k127_1413412_2	1122169.AREN01000003_gene1128	2.098e-17	94.0	COG1073@1|root,COG1073@2|Bacteria,1QB0F@1224|Proteobacteria,1T6HE@1236|Gammaproteobacteria,1JDG8@118969|Legionellales	118969|Legionellales	S	alpha beta	sidB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF818
SRR25158357_k127_1419477_0	391896.A1I_00355	9.893e-229	720.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,47F2D@766|Rickettsiales	766|Rickettsiales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158357_k127_1419477_1	315456.RF_0110	2.126e-145	470.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,47F2H@766|Rickettsiales	766|Rickettsiales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158357_k127_1419477_6	1449065.JMLL01000011_gene2092	6.076e-28	116.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,43K87@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the HesB IscA family	erpA	-	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158357_k127_1419477_4	315456.RF_0961	3.533e-33	134.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,47FM0@766|Rickettsiales	766|Rickettsiales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158357_k127_1419477_5	1430440.MGMSRv2_3711	1.68e-30	128.0	COG3334@1|root,COG3334@2|Bacteria,1RKF6@1224|Proteobacteria,2TRR1@28211|Alphaproteobacteria,2JSTD@204441|Rhodospirillales	204441|Rhodospirillales	S	PFAM MgtE intracellular	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
SRR25158357_k127_1419477_2	1528098.NOVO_01450	1.82e-88	301.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2TR4F@28211|Alphaproteobacteria,47F3N@766|Rickettsiales	766|Rickettsiales	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
SRR25158357_k127_1419477_8	269796.Rru_A2841	5.812e-12	73.0	COG1580@1|root,COG1580@2|Bacteria,1RH5D@1224|Proteobacteria,2U9BF@28211|Alphaproteobacteria,2JST8@204441|Rhodospirillales	204441|Rhodospirillales	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
SRR25158357_k127_1419477_7	1333998.M2A_1233	5.344e-26	116.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,2U06G@28211|Alphaproteobacteria,4BQQT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	N	Flagella basal body rod protein	flgF	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158357_k127_1419477_3	1207063.P24_10950	7.634e-62	222.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,2JQAH@204441|Rhodospirillales	204441|Rhodospirillales	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158357_k127_1419477_9	1122169.AREN01000006_gene314	1.492e-08	64.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1JCX3@118969|Legionellales	118969|Legionellales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
SRR25158357_k127_1454995_30	336407.RBE_1041	4.068e-29	119.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,47FHZ@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158357_k127_1454995_3	293613.A1E_04270	3.5e-213	668.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria,47EWF@766|Rickettsiales	766|Rickettsiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158357_k127_1454995_28	336407.RBE_1043	1.862e-35	140.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2U79D@28211|Alphaproteobacteria,47FGQ@766|Rickettsiales	766|Rickettsiales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158357_k127_1454995_33	488538.SAR116_2409	8.742e-12	67.0	COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria,4BR4M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158357_k127_1454995_18	257363.RT0634	1.229e-60	213.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria,47FBU@766|Rickettsiales	766|Rickettsiales	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158357_k127_1454995_27	315456.RF_0294	4.438e-37	142.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria,47FNM@766|Rickettsiales	766|Rickettsiales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158357_k127_1454995_16	315456.RF_0293	1.9e-66	230.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,47FCI@766|Rickettsiales	766|Rickettsiales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158357_k127_1454995_22	336407.RBE_1048	3.006e-47	172.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2U6ZH@28211|Alphaproteobacteria,47FFI@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158357_k127_1454995_29	293614.A1C_05040	3.648e-33	130.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2UC01@28211|Alphaproteobacteria,47FKZ@766|Rickettsiales	766|Rickettsiales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158357_k127_1454995_10	391896.A1I_02095	1.011e-85	286.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria,47F90@766|Rickettsiales	766|Rickettsiales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158357_k127_1454995_23	334545.CCMG01000008_gene523	3.173e-45	165.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,47FGH@766|Rickettsiales	766|Rickettsiales	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158357_k127_1454995_19	452659.RrIowa_1187	4.275e-52	186.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria,47FD2@766|Rickettsiales	766|Rickettsiales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158357_k127_1454995_32	195105.CN97_03820	1.267e-27	113.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158357_k127_1454995_34	391896.A1I_02075	2.84e-11	66.0	COG0255@1|root,COG0255@2|Bacteria,1Q67D@1224|Proteobacteria,2VCEG@28211|Alphaproteobacteria,47FR8@766|Rickettsiales	766|Rickettsiales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158357_k127_1454995_17	293614.A1C_05070	7.004e-64	220.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,47FB1@766|Rickettsiales	766|Rickettsiales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158357_k127_1454995_13	1528098.NOVO_06135	3.282e-78	267.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,47F64@766|Rickettsiales	766|Rickettsiales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158357_k127_1454995_24	452659.RrIowa_1192	1.254e-40	153.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2U96X@28211|Alphaproteobacteria,47FJ9@766|Rickettsiales	766|Rickettsiales	J	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158357_k127_1454995_21	293613.A1E_04350	1.078e-47	171.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2U95S@28211|Alphaproteobacteria,47FHT@766|Rickettsiales	766|Rickettsiales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158357_k127_1454995_6	293613.A1E_04355	3.647e-136	437.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2TTKD@28211|Alphaproteobacteria,47EZ2@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158357_k127_1454995_31	336407.RBE_1060	9.594e-29	118.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2UBQ1@28211|Alphaproteobacteria,47FMH@766|Rickettsiales	766|Rickettsiales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158357_k127_1454995_14	293614.A1C_05100	1.114e-70	244.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria,47F8F@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158357_k127_1454995_11	1122180.Lokhon_00462	4.682e-83	280.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria,2P8F4@245186|Loktanella	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158357_k127_1454995_25	1220535.IMCC14465_16530	8.981e-40	149.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,4BQFP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158357_k127_1454995_2	91604.ID47_08580	1.304e-214	670.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,47EUU@766|Rickettsiales	766|Rickettsiales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158357_k127_1454995_36	661367.LLO_0471	2.635e-08	58.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1454995_15	336407.RBE_1065	5.591e-68	238.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,47FBR@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158357_k127_1454995_12	1105110.MC5_06020	2.381e-81	277.0	COG3736@1|root,COG3736@2|Bacteria,1MXRC@1224|Proteobacteria,2U2AZ@28211|Alphaproteobacteria,47FGS@766|Rickettsiales	766|Rickettsiales	U	VirB8 protein	-	-	-	ko:K03203	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	VirB8
SRR25158357_k127_1454995_20	293613.A1E_04175	3.805e-50	181.0	COG3504@1|root,COG3504@2|Bacteria,1NZG6@1224|Proteobacteria,2UTMZ@28211|Alphaproteobacteria,47FHF@766|Rickettsiales	766|Rickettsiales	U	COG3504 Type IV secretory pathway, VirB9 components	virB9	-	-	ko:K03204	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagX
SRR25158357_k127_1454995_35	1144888.CM001467_gene1301	1.814e-09	62.0	COG2948@1|root,COG2948@2|Bacteria,1MU7U@1224|Proteobacteria,2U90W@28211|Alphaproteobacteria,47F8K@766|Rickettsiales	766|Rickettsiales	U	type IV secretory pathway, VirB10 components	virB10	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
SRR25158357_k127_1454995_9	336407.RBE_1016	2.808e-98	331.0	COG2948@1|root,COG2948@2|Bacteria,1MU7U@1224|Proteobacteria,2U90W@28211|Alphaproteobacteria,47F8K@766|Rickettsiales	766|Rickettsiales	U	type IV secretory pathway, VirB10 components	virB10	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
SRR25158357_k127_1454995_4	1144888.CM001467_gene1300	5.087e-159	506.0	COG0630@1|root,COG0630@2|Bacteria,1QUJ6@1224|Proteobacteria,2TW2D@28211|Alphaproteobacteria,47EXK@766|Rickettsiales	766|Rickettsiales	NU	Type IV secretory pathway, VirB11 components, and related ATPases involved in	virB11	-	-	ko:K03196	ko03070,ko05120,map03070,map05120	M00333,M00564	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T2SSE
SRR25158357_k127_1454995_0	334545.CCMG01000017_gene1315	3.342e-316	974.0	COG3505@1|root,COG3505@2|Bacteria,1MV1G@1224|Proteobacteria,2TR6N@28211|Alphaproteobacteria,47EW8@766|Rickettsiales	766|Rickettsiales	U	Type IV secretion system protein VirD4	virD4	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
SRR25158357_k127_1454995_5	272951.rsib_orf310	1.719e-137	452.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,47G1X@766|Rickettsiales	766|Rickettsiales	FP	Ppx/GppA phosphatase family	gppA	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158357_k127_1454995_26	315456.RF_0666	1.224e-39	153.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2UBYU@28211|Alphaproteobacteria,47FMQ@766|Rickettsiales	766|Rickettsiales	C	Cytochrome b561	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
SRR25158357_k127_1454995_7	391896.A1I_02720	1.78e-110	364.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,47EXI@766|Rickettsiales	766|Rickettsiales	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158357_k127_1454995_1	315456.RF_0627	1.423e-294	908.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,47EY0@766|Rickettsiales	766|Rickettsiales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158357_k127_1454995_8	315456.RF_0629	1.381e-109	360.0	COG1565@1|root,COG1622@1|root,COG1565@2|Bacteria,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,47EZD@766|Rickettsiales	766|Rickettsiales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158357_k127_1467707_1	1230343.CANP01000031_gene2358	1.388e-155	497.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria,1JD80@118969|Legionellales	118969|Legionellales	F	Metal binding domain of Ada	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158357_k127_1467707_2	1399147.P618_200064	3.689e-80	274.0	COG4912@1|root,COG4912@2|Bacteria,1Q8WI@1224|Proteobacteria,2VD0W@28211|Alphaproteobacteria,47G6N@766|Rickettsiales	766|Rickettsiales	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158357_k127_1467707_0	334545.CCMG01000008_gene431	1.457e-291	914.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,47ETS@766|Rickettsiales	766|Rickettsiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158357_k127_1471567_4	796620.VIBC2010_14044	1.617e-06	57.0	COG0834@1|root,COG0834@2|Bacteria,1RBXC@1224|Proteobacteria,1S31V@1236|Gammaproteobacteria,1XWHX@135623|Vibrionales	135623|Vibrionales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158357_k127_1471567_2	1144888.CM001467_gene1002	2.377e-66	229.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,47FCX@766|Rickettsiales	766|Rickettsiales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158357_k127_1471567_1	391896.A1I_05245	2.903e-74	265.0	COG4632@1|root,COG4632@2|Bacteria,1NTF0@1224|Proteobacteria	1224|Proteobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA,SPOR
SRR25158357_k127_1471567_3	1286170.RORB6_15315	4.692e-10	68.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Periplasmic or secreted lipoprotein	osmY	GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158357_k127_1471567_0	391896.A1I_02990	2.002e-130	423.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47ET5@766|Rickettsiales	766|Rickettsiales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	abcT3	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_147295_9	391896.A1I_00425	7.538e-62	221.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,47FGN@766|Rickettsiales	766|Rickettsiales	O	May be required for disulfide bond formation in some proteins	dsbG	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158357_k127_147295_27	488538.SAR116_1100	0.0006191	46.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,4BR0U@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158357_k127_147295_5	272951.rsib_orf687	2.774e-99	329.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,47EYQ@766|Rickettsiales	766|Rickettsiales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158357_k127_147295_16	391896.A1I_00410	2.759e-27	112.0	COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UGGG@28211|Alphaproteobacteria,47FMN@766|Rickettsiales	766|Rickettsiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158357_k127_147295_20	391896.A1I_00405	1.778e-18	91.0	COG0711@1|root,COG0711@2|Bacteria,1Q76H@1224|Proteobacteria,2VDAY@28211|Alphaproteobacteria,47FU5@766|Rickettsiales	766|Rickettsiales	C	COG0711 F0F1-type ATP synthase, subunit b	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,YMF19
SRR25158357_k127_147295_18	391896.A1I_00400	1.437e-22	103.0	COG0711@1|root,COG0711@2|Bacteria,1N8XR@1224|Proteobacteria,2V49S@28211|Alphaproteobacteria,47FUN@766|Rickettsiales	766|Rickettsiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158357_k127_147295_10	315456.RF_0415	3.632e-58	211.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2TS2V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type Mn2 Zn2 transport systems permease components	znuB	GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158357_k127_147295_7	336407.RBE_1422	2.306e-81	276.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,47F9W@766|Rickettsiales	766|Rickettsiales	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158357_k127_147295_11	293613.A1E_05345	3.992e-52	188.0	COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UA8D@28211|Alphaproteobacteria,47FH4@766|Rickettsiales	766|Rickettsiales	M	COG4520 Surface antigen	omp	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Rick_17kDa_Anti
SRR25158357_k127_147295_4	293613.A1E_05340	1.938e-104	347.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,47F5I@766|Rickettsiales	766|Rickettsiales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	p34	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
SRR25158357_k127_147295_14	272947.RP831	7.217e-44	164.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,47FGG@766|Rickettsiales	766|Rickettsiales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158357_k127_147295_6	1528098.NOVO_06065	1.106e-83	286.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TR5A@28211|Alphaproteobacteria,47F55@766|Rickettsiales	766|Rickettsiales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
SRR25158357_k127_147295_13	1101195.Meth11DRAFT_1515	2.718e-49	186.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,2KKMD@206350|Nitrosomonadales	206350|Nitrosomonadales	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
SRR25158357_k127_147295_26	1265313.HRUBRA_00749	0.0001011	44.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria,1J9CZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
SRR25158357_k127_147295_8	1333998.M2A_2043	1.257e-69	244.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,4BQ01@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC-2 type transporter	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158357_k127_147295_1	334545.CCMG01000009_gene783	2.895e-200	632.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,47EVT@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158357_k127_147295_0	272951.rsib_orf858	1.528e-296	929.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,47ETD@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
SRR25158357_k127_147295_25	1105110.MC5_07120	3.315e-09	61.0	2AD9U@1|root,312Z2@2|Bacteria,1PRH9@1224|Proteobacteria,2V3SF@28211|Alphaproteobacteria,47FVQ@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_147295_24	336407.RBE_0895	2.398e-10	70.0	COG4886@1|root,COG4886@2|Bacteria,1NQCE@1224|Proteobacteria,2UUA1@28211|Alphaproteobacteria,47FPP@766|Rickettsiales	766|Rickettsiales	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
SRR25158357_k127_147295_21	192875.XP_004347357.1	5.467e-16	83.0	KOG4308@1|root,KOG4308@2759|Eukaryota	2759|Eukaryota	S	interleukin-8 biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
SRR25158357_k127_147295_12	78898.MVEG_01547T0	1.68e-51	197.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38KU9@33154|Opisthokonta,3NXW6@4751|Fungi	4751|Fungi	AT	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
SRR25158357_k127_147295_23	391896.A1I_00340	4.302e-11	63.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,47F0I@766|Rickettsiales	766|Rickettsiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158357_k127_147295_22	1282876.BAOK01000001_gene1980	1.207e-15	79.0	2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria,4BQY0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	ETC complex I subunit conserved region	MA20_30235	-	1.6.5.3	ko:K00329	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	ETC_C1_NDUFA4
SRR25158357_k127_147295_19	336407.RBE_0766	9.614e-22	98.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,47FT7@766|Rickettsiales	766|Rickettsiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158357_k127_147295_3	1105110.MC5_05705	2.447e-106	354.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,47FAH@766|Rickettsiales	766|Rickettsiales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158357_k127_147295_17	227377.CBU_0433	6.841e-25	110.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1JE6A@118969|Legionellales	118969|Legionellales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158357_k127_147295_15	1105110.MC5_06765	5.69e-28	121.0	2E521@1|root,32ZVA@2|Bacteria,1NH3G@1224|Proteobacteria,2UKE1@28211|Alphaproteobacteria,47FS9@766|Rickettsiales	766|Rickettsiales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SRR25158357_k127_147295_2	315456.RF_1073	3.221e-114	374.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,47F2X@766|Rickettsiales	766|Rickettsiales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158357_k127_1482468_1	336407.RBE_1325	1.569e-200	632.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,47EUJ@766|Rickettsiales	766|Rickettsiales	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158357_k127_1482468_6	556263.FSEG_01062	1.085e-05	57.0	COG2369@1|root,COG2369@2|Bacteria,37AJ9@32066|Fusobacteria	32066|Fusobacteria	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
SRR25158357_k127_1482468_2	1034943.BN1094_03329	7.179e-95	325.0	COG2271@1|root,COG2271@2|Bacteria,1R263@1224|Proteobacteria,1T5HZ@1236|Gammaproteobacteria,1JGQS@118969|Legionellales	118969|Legionellales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158357_k127_1482468_0	1238182.C882_4129	6.455e-216	680.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria,2JQTZ@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158357_k127_1482468_4	1177928.TH2_03540	1.298e-71	251.0	COG0589@1|root,COG0589@2|Bacteria,1PAFP@1224|Proteobacteria,2U0JA@28211|Alphaproteobacteria,2JQ6U@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158357_k127_1482468_3	1528098.NOVO_04745	3.137e-76	271.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,47EXW@766|Rickettsiales	766|Rickettsiales	G	Phosphoglucose isomerase	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158357_k127_1482468_5	163164.WD_0316	5.679e-63	221.0	COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,2V3J4@28211|Alphaproteobacteria,47G3E@766|Rickettsiales	766|Rickettsiales	C	Na+/H+ antiporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
SRR25158357_k127_1513570_3	525897.Dbac_1528	1.5e-71	268.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,42MHY@68525|delta/epsilon subdivisions,2WTPK@28221|Deltaproteobacteria,2M8G1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg,Fil_haemagg_2,Haemagg_act
SRR25158357_k127_1513570_0	1198232.CYCME_2297	9.919e-215	674.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,460AZ@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158357_k127_1513570_2	1198232.CYCME_2296	3.274e-155	496.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RN0N@1236|Gammaproteobacteria,460KE@72273|Thiotrichales	72273|Thiotrichales	C	subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158357_k127_1513570_1	1411685.U062_01583	1.371e-178	571.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1J82Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	DNA photolyase	phrB	GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158357_k127_1515431_3	1380600.AUYN01000007_gene3400	2.047e-68	234.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1I1C6@117743|Flavobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1515431_0	1380600.AUYN01000007_gene3399	2.289e-97	322.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
SRR25158357_k127_1515431_2	1178825.ALIH01000003_gene2020	4.727e-85	283.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,1I1CY@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158357_k127_1515431_1	1178825.ALIH01000003_gene2021	7.578e-91	301.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,1HYCZ@117743|Flavobacteriia	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
SRR25158357_k127_1515431_5	1137281.D778_02106	2.218e-50	182.0	2AT2U@1|root,31IIU@2|Bacteria,4NS9K@976|Bacteroidetes,1I3WD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1515431_6	1137281.D778_02105	4.822e-45	163.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158357_k127_1515431_4	1178825.ALIH01000003_gene2023	2.868e-52	184.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158357_k127_1573191_2	315456.RF_1028	4.7e-83	280.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,47F79@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
SRR25158357_k127_1573191_4	367336.OM2255_07060	2.998e-30	121.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158357_k127_1573191_3	336407.RBE_0143	1.264e-62	222.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,47FCD@766|Rickettsiales	766|Rickettsiales	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158357_k127_1573191_0	272951.rsib_orf517	4.76e-228	714.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,47EW2@766|Rickettsiales	766|Rickettsiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158357_k127_1573191_1	452659.RrIowa_0237	3.726e-89	298.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,47F34@766|Rickettsiales	766|Rickettsiales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158357_k127_1589100_0	1105110.MC5_03100	8.606e-169	537.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,47EWY@766|Rickettsiales	766|Rickettsiales	I	Propionyl-CoA carboxylase alpha	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158357_k127_1589100_1	555793.WSK_1308	5.528e-22	110.0	COG0793@1|root,COG0793@2|Bacteria,1R5Y0@1224|Proteobacteria,2U8CV@28211|Alphaproteobacteria,2K0XF@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158357_k127_1592439_0	257363.RT0658	1.607e-162	524.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,47EWC@766|Rickettsiales	766|Rickettsiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158357_k127_1598688_4	315456.RF_1022	2.067e-94	323.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2U8YP@28211|Alphaproteobacteria,47FNH@766|Rickettsiales	766|Rickettsiales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	pbpE	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158357_k127_1598688_3	452659.RrIowa_0081	1.523e-128	419.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,47ET7@766|Rickettsiales	766|Rickettsiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158357_k127_1598688_12	334545.CCMG01000015_gene1262	1.172e-51	187.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,47FI1@766|Rickettsiales	766|Rickettsiales	C	Cytochrome C	cycM	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
SRR25158357_k127_1598688_14	272951.rsib_orf366	2.834e-35	139.0	COG1585@1|root,COG1585@2|Bacteria,1NJK6@1224|Proteobacteria,2UNJF@28211|Alphaproteobacteria,47FTA@766|Rickettsiales	766|Rickettsiales	OU	implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158357_k127_1598688_11	272951.rsib_orf750	9.719e-55	199.0	COG0671@1|root,COG0671@2|Bacteria,1NIPK@1224|Proteobacteria,2VDB6@28211|Alphaproteobacteria,47FUZ@766|Rickettsiales	766|Rickettsiales	I	COG0671 Membrane-associated phospholipid phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158357_k127_1598688_8	357244.OTBS_1782	3.842e-59	207.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2U70K@28211|Alphaproteobacteria,47FAT@766|Rickettsiales	766|Rickettsiales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158357_k127_1598688_6	336407.RBE_1161	7.732e-70	239.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,47FAM@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158357_k127_1598688_2	391896.A1I_01480	0.0	1114.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,47EWM@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158357_k127_1598688_15	391896.A1I_01485	1.95e-18	86.0	COG0690@1|root,COG0690@2|Bacteria,1Q7IA@1224|Proteobacteria,2VDPI@28211|Alphaproteobacteria,47GM7@766|Rickettsiales	766|Rickettsiales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158357_k127_1598688_7	1144888.CM001467_gene1554	1.744e-67	233.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria,47FEE@766|Rickettsiales	766|Rickettsiales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158357_k127_1598688_9	91604.ID47_08625	8.083e-59	207.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria,47FBQ@766|Rickettsiales	766|Rickettsiales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158357_k127_1598688_5	1105110.MC5_07170	2.171e-90	302.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria,47F5R@766|Rickettsiales	766|Rickettsiales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158357_k127_1598688_10	334545.CCMG01000014_gene1097	1.332e-58	207.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,47FI3@766|Rickettsiales	766|Rickettsiales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158357_k127_1598688_13	1123227.KB899337_gene1211	1.331e-45	168.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2JSU1@204441|Rhodospirillales	204441|Rhodospirillales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158357_k127_1598688_1	1282876.BAOK01000001_gene1711	0.0	1785.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,4BPI1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158357_k127_1598688_0	257363.RT0130	0.0	2082.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,47ETY@766|Rickettsiales	766|Rickettsiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158357_k127_1603639_5	1144888.CM001467_gene156	3.596e-109	360.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2U4E1@28211|Alphaproteobacteria,47ETP@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP7	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1
SRR25158357_k127_1603639_9	1144888.CM001467_gene354	9.551e-32	126.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,47FRZ@766|Rickettsiales	766|Rickettsiales	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158357_k127_1603639_2	391896.A1I_07665	7.144e-135	434.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,47F02@766|Rickettsiales	766|Rickettsiales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
SRR25158357_k127_1603639_0	1144888.CM001467_gene1147	0.0	1047.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,47EXX@766|Rickettsiales	766|Rickettsiales	C	Malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
SRR25158357_k127_1603639_6	391896.A1I_02550	4.609e-102	340.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2TV2I@28211|Alphaproteobacteria,47G0N@766|Rickettsiales	766|Rickettsiales	S	Sodium Bile acid symporter family	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158357_k127_1603639_7	336407.RBE_1237	1.537e-38	149.0	COG1714@1|root,COG1714@2|Bacteria,1NKF8@1224|Proteobacteria,2VGAW@28211|Alphaproteobacteria,47FS1@766|Rickettsiales	766|Rickettsiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158357_k127_1603639_3	1444711.CCJF01000005_gene1477	1.081e-116	387.0	COG0477@1|root,COG2814@2|Bacteria,2JGF2@204428|Chlamydiae	204428|Chlamydiae	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRR25158357_k127_1603639_8	384765.SIAM614_03066	1.826e-32	131.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2UC00@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FG	Histidine triad (HIT) protein	MA20_21960	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158357_k127_1603639_4	363253.LIB020	5.382e-112	374.0	COG1301@1|root,COG1301@2|Bacteria,1R3SN@1224|Proteobacteria,42WC5@68525|delta/epsilon subdivisions,2WS97@28221|Deltaproteobacteria,2M9XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158357_k127_1603639_13	1224746.B932_0245	1.999e-15	76.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158357_k127_1603639_10	293614.A1C_04780	5.684e-24	105.0	COG0594@1|root,COG0594@2|Bacteria	2|Bacteria	J	ribonuclease P activity	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158357_k127_1603639_1	391896.A1I_06065	2.528e-223	724.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1603639_12	315456.RF_0040	2.057e-21	99.0	2AKJJ@1|root,31BBN@2|Bacteria,1Q75Z@1224|Proteobacteria,2VDAF@28211|Alphaproteobacteria,47FSQ@766|Rickettsiales	766|Rickettsiales	S	Family of unknown function (DUF5394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5394
SRR25158357_k127_1603639_11	86106.I862_05575	3.434e-22	105.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158357_k127_1606805_2	315456.RF_1349	2.994e-106	351.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47F3Y@766|Rickettsiales	766|Rickettsiales	EGP	Major facilitator	proP6	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158357_k127_1606805_0	452659.RrIowa_1545	4.529e-111	362.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,2TUM2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
SRR25158357_k127_1606805_1	334545.CCMG01000002_gene118	2.514e-109	361.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,47F98@766|Rickettsiales	766|Rickettsiales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
SRR25158357_k127_1606805_4	293614.A1C_03565	3.23e-33	131.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,47FMP@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158357_k127_1606805_3	1105110.MC5_04530	1.073e-41	155.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,47EVH@766|Rickettsiales	766|Rickettsiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158357_k127_1623337_5	293613.A1E_00480	2.236e-23	100.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,47FRK@766|Rickettsiales	766|Rickettsiales	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158357_k127_1623337_2	336407.RBE_1279	1.89e-26	111.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,47FNA@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158357_k127_1623337_4	334545.CCMG01000027_gene1621	1.348e-25	111.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,47FMT@766|Rickettsiales	766|Rickettsiales	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158357_k127_1623337_3	391896.A1I_01745	3.248e-26	109.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,2UHTU@28211|Alphaproteobacteria,47FPB@766|Rickettsiales	766|Rickettsiales	S	ChaB	chaB	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
SRR25158357_k127_1623337_0	244582.JQAK01000004_gene219	2.478e-36	142.0	COG1633@1|root,COG1633@2|Bacteria,1N452@1224|Proteobacteria,2UDKD@28211|Alphaproteobacteria,47FEM@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
SRR25158357_k127_1623337_1	244581.IM40_00320	1.658e-27	116.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,47F4H@766|Rickettsiales	766|Rickettsiales	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158357_k127_1638921_5	1198232.CYCME_0570	1.726e-28	117.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,4606M@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
SRR25158357_k127_1638921_1	272951.rsib_orf752	6.95e-86	290.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,47F84@766|Rickettsiales	766|Rickettsiales	E	COG1126 ABC-type polar amino acid transport system, ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158357_k127_1638921_2	272951.rsib_orf539	2.94e-75	258.0	COG0765@1|root,COG0765@2|Bacteria,1P3W6@1224|Proteobacteria,2U6NW@28211|Alphaproteobacteria,47F6V@766|Rickettsiales	766|Rickettsiales	E	transport system permease	yqiY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158357_k127_1638921_4	856793.MICA_1697	4.094e-41	161.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2TTHN@28211|Alphaproteobacteria,4BQTZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
SRR25158357_k127_1638921_6	391896.A1I_02580	6.028e-22	96.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,47FMY@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158357_k127_1638921_3	334545.CCMG01000008_gene452	1.793e-52	186.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,47FE9@766|Rickettsiales	766|Rickettsiales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158357_k127_1638921_0	336407.RBE_1184	9.481e-134	433.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,47F5C@766|Rickettsiales	766|Rickettsiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158357_k127_1661799_0	315456.RF_0693	1.074e-56	225.0	COG4625@1|root,COG4625@2|Bacteria,1PHUK@1224|Proteobacteria,2U1YI@28211|Alphaproteobacteria,47GPX@766|Rickettsiales	28211|Alphaproteobacteria	S	protein with a C-terminal OMP (outer membrane protein) domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
SRR25158357_k127_1661799_2	747.DR93_1267	2.21e-08	64.0	2EC8Z@1|root,3367C@2|Bacteria,1NDEN@1224|Proteobacteria,1SEP7@1236|Gammaproteobacteria,1YABW@135625|Pasteurellales	1236|Gammaproteobacteria	S	SMI1 / KNR4 family	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4,SUKH_6
SRR25158357_k127_1661799_3	95619.PM1_0201810	1.83e-06	58.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	DUF637,Fil_haemagg,Fil_haemagg_2,Haemagg_act
SRR25158357_k127_1661799_1	293613.A1E_02425	7.234e-54	194.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria,47EXP@766|Rickettsiales	766|Rickettsiales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158357_k127_1673321_7	331869.BAL199_26612	2.754e-115	378.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,4BPJR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158357_k127_1673321_8	336407.RBE_1282	1.869e-112	370.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,47ET1@766|Rickettsiales	766|Rickettsiales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158357_k127_1673321_20	293613.A1E_02345	6.915e-44	162.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,47FGE@766|Rickettsiales	766|Rickettsiales	S	Belongs to the HesB IscA family	iscA2	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158357_k127_1673321_15	157072.XP_008872100.1	1.623e-62	216.0	COG0822@1|root,KOG3361@2759|Eukaryota	2759|Eukaryota	C	iron-sulfur transferase activity	ISCU	GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005198,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008033,GO:0008150,GO:0008152,GO:0008198,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031974,GO:0032947,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044571,GO:0046483,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097428,GO:0098771,GO:1901360,GO:1901564,GO:1990221	-	ko:K22068	-	-	-	-	ko00000,ko03029	-	-	-	NifU_N
SRR25158357_k127_1673321_0	391896.A1I_03930	2.02e-207	651.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,47EYU@766|Rickettsiales	766|Rickettsiales	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158357_k127_1673321_11	334545.CCMG01000007_gene269	8.754e-101	340.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,47F0P@766|Rickettsiales	766|Rickettsiales	E	COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	spl1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158357_k127_1673321_22	336407.RBE_0949	3.121e-43	162.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2U5B9@28211|Alphaproteobacteria,47FFG@766|Rickettsiales	766|Rickettsiales	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
SRR25158357_k127_1673321_4	1122134.KB893651_gene2359	4.433e-132	427.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XHPG@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the RimK family	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
SRR25158357_k127_1673321_5	237368.SCABRO_03316	4.651e-131	426.0	COG3608@1|root,COG3608@2|Bacteria,2IX28@203682|Planctomycetes	203682|Planctomycetes	S	succinate dehydrogenase subunit	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
SRR25158357_k127_1673321_18	237368.SCABRO_03315	7.446e-49	179.0	COG4067@1|root,COG4067@2|Bacteria,2J12V@203682|Planctomycetes	203682|Planctomycetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
SRR25158357_k127_1673321_25	1144888.CM001467_gene998	2.144e-21	95.0	COG4118@1|root,COG4118@2|Bacteria,1NME9@1224|Proteobacteria,2UMMS@28211|Alphaproteobacteria,47GMQ@766|Rickettsiales	766|Rickettsiales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158357_k127_1673321_21	1144888.CM001467_gene999	1.905e-43	162.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2UKC3@28211|Alphaproteobacteria,47GCQ@766|Rickettsiales	766|Rickettsiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158357_k127_1673321_14	334545.CCMG01000018_gene1396	1.175e-77	267.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,47FD1@766|Rickettsiales	766|Rickettsiales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158357_k127_1673321_3	336407.RBE_0702	9.788e-144	465.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,47EWZ@766|Rickettsiales	766|Rickettsiales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158357_k127_1673321_9	86106.I862_04860	8.077e-111	373.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria,47EUK@766|Rickettsiales	766|Rickettsiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158357_k127_1673321_2	334545.CCMG01000008_gene560	7.719e-159	524.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,47F1W@766|Rickettsiales	766|Rickettsiales	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
SRR25158357_k127_1673321_17	1144888.CM001467_gene527	3.971e-57	209.0	COG0760@1|root,COG0760@2|Bacteria,1PCDR@1224|Proteobacteria,2V4A3@28211|Alphaproteobacteria,47FUS@766|Rickettsiales	766|Rickettsiales	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
SRR25158357_k127_1673321_12	1105110.MC5_02715	1.845e-93	314.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,47F8R@766|Rickettsiales	766|Rickettsiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158357_k127_1673321_10	1144888.CM001467_gene1535	6.182e-105	348.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,47F6T@766|Rickettsiales	766|Rickettsiales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158357_k127_1673321_16	315456.RF_1176	1.155e-58	211.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,47FDT@766|Rickettsiales	766|Rickettsiales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158357_k127_1673321_13	293613.A1E_00585	3.642e-80	276.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,47FF7@766|Rickettsiales	766|Rickettsiales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158357_k127_1673321_19	86106.I862_03075	2.554e-48	182.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,47FF6@766|Rickettsiales	766|Rickettsiales	V	Ami_2	-	-	3.5.1.28	ko:K11066	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
SRR25158357_k127_1673321_24	334545.CCMG01000014_gene1027	7.164e-36	142.0	COG3047@1|root,COG3047@2|Bacteria,1Q7J8@1224|Proteobacteria,2VDQI@28211|Alphaproteobacteria,47GPC@766|Rickettsiales	766|Rickettsiales	M	COG3047 Outer membrane protein W	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158357_k127_1673321_26	257363.RT0057	8.581e-06	51.0	COG3047@1|root,COG3047@2|Bacteria,1Q7J8@1224|Proteobacteria,2VDQI@28211|Alphaproteobacteria,47GPC@766|Rickettsiales	766|Rickettsiales	M	COG3047 Outer membrane protein W	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158357_k127_1673321_6	272951.rsib_orf605	2.19e-124	405.0	COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria,47F5H@766|Rickettsiales	766|Rickettsiales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
SRR25158357_k127_1673321_1	336407.RBE_0020	3.761e-172	549.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2U7KJ@28211|Alphaproteobacteria,47GQ3@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP1	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158357_k127_1673321_23	59196.RICGR_0561	2.217e-39	158.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1JCGZ@118969|Legionellales	118969|Legionellales	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
SRR25158357_k127_1689845_9	293614.A1C_01775	2.379e-41	155.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,47FAA@766|Rickettsiales	766|Rickettsiales	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158357_k127_1689845_1	336407.RBE_0082	1.422e-108	359.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2TRRX@28211|Alphaproteobacteria,47ETN@766|Rickettsiales	766|Rickettsiales	P	COG0861 Membrane protein TerC, possibly involved in tellurium resistance	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158357_k127_1689845_5	675814.VIC_002647	1.123e-69	240.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1XWW8@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
SRR25158357_k127_1689845_11	78898.MVEG_06049T0	4.142e-29	131.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38KU9@33154|Opisthokonta,3NXW6@4751|Fungi	4751|Fungi	AT	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
SRR25158357_k127_1689845_7	244582.JQAK01000004_gene282	8.484e-61	214.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2TRBC@28211|Alphaproteobacteria,47GN0@766|Rickettsiales	766|Rickettsiales	J	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158357_k127_1689845_8	525897.Dbac_1210	1.792e-53	192.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2WK2U@28221|Deltaproteobacteria,2MAU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158357_k127_1689845_6	1230343.CANP01000043_gene3336	6.657e-68	241.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1JD8U@118969|Legionellales	118969|Legionellales	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1689845_3	86106.I862_01290	7.807e-86	291.0	28H5T@1|root,2Z7IB@2|Bacteria,1N7V9@1224|Proteobacteria,2TTZQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1689845_4	336407.RBE_0401	1.018e-69	241.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,47F4A@766|Rickettsiales	766|Rickettsiales	S	hmm tigr01630	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
SRR25158357_k127_1689845_2	391896.A1I_05750	9.535e-99	329.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,47F4A@766|Rickettsiales	766|Rickettsiales	S	hmm tigr01630	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
SRR25158357_k127_1689845_0	336407.RBE_0759	6.851e-140	454.0	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,47EUP@766|Rickettsiales	766|Rickettsiales	S	Phage portal protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
SRR25158357_k127_1689845_10	257363.RT0421	7.996e-37	145.0	COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,47FN2@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
SRR25158357_k127_1695342_14	86106.I862_01355	1.934e-05	53.0	COG5385@1|root,COG5385@2|Bacteria,1PD1Z@1224|Proteobacteria,2UGVI@28211|Alphaproteobacteria,47FSE@766|Rickettsiales	766|Rickettsiales	S	Histidine phosphotransferase C-terminal domain	-	-	-	ko:K13588	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001	-	-	-	HPTransfase
SRR25158357_k127_1695342_1	272951.rsib_orf1086	4.467e-212	667.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,47EZ7@766|Rickettsiales	766|Rickettsiales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158357_k127_1695342_2	336407.RBE_0990	3.553e-208	658.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47G3D@766|Rickettsiales	766|Rickettsiales	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TLC
SRR25158357_k127_1695342_0	315456.RF_1015	1.839e-227	712.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,47F3K@766|Rickettsiales	766|Rickettsiales	C	isocitrate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158357_k127_1695342_6	452471.Aasi_0563	3.068e-100	347.0	COG0317@1|root,COG0591@1|root,COG0317@2|Bacteria,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	HD_4,SSF
SRR25158357_k127_1695342_9	391896.A1I_06065	9.952e-83	287.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1695342_13	1220535.IMCC14465_05590	5.011e-14	82.0	COG0671@1|root,COG0671@2|Bacteria,1PSMD@1224|Proteobacteria,2UWMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158357_k127_1695342_12	1173026.Glo7428_4747	4.993e-27	119.0	COG4625@1|root,COG4625@2|Bacteria,1G7EK@1117|Cyanobacteria	1117|Cyanobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1695342_15	232721.Ajs_3811	7.942e-05	55.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,4AB3F@80864|Comamonadaceae	28216|Betaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
SRR25158357_k127_1695342_11	452659.RrIowa_0798	3.47e-49	178.0	COG1396@1|root,COG1396@2|Bacteria,1RIM2@1224|Proteobacteria,2UAD5@28211|Alphaproteobacteria,47GKZ@766|Rickettsiales	766|Rickettsiales	K	Helix-turn-helix domain	hipB	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158357_k127_1695342_7	336407.RBE_0675	1.574e-99	331.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TTN5@28211|Alphaproteobacteria,47F7W@766|Rickettsiales	766|Rickettsiales	S	Ribonuclease, BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158357_k127_1695342_10	1124780.ANNU01000061_gene915	3.899e-55	201.0	COG3022@1|root,COG3022@2|Bacteria,4NFP2@976|Bacteroidetes,47Q7T@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
SRR25158357_k127_1695342_3	315456.RF_1334	2.92e-160	514.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,47EY2@766|Rickettsiales	766|Rickettsiales	H	5-aminolevulinic acid synthase	hemA	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158357_k127_1695342_8	334545.CCMG01000014_gene988	3.761e-95	318.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,47F5X@766|Rickettsiales	766|Rickettsiales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158357_k127_1695342_5	1144888.CM001467_gene59	1.023e-115	383.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,47F8U@766|Rickettsiales	766|Rickettsiales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158357_k127_1695342_4	357244.OTBS_0252	2.833e-159	507.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,47EW0@766|Rickettsiales	766|Rickettsiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158357_k127_1724198_20	336407.RBE_0088	3.646e-22	95.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,47EU0@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158357_k127_1724198_7	391896.A1I_07505	1.021e-84	285.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,47EU0@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158357_k127_1724198_1	1105110.MC5_03965	1.853e-127	422.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,47EYV@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158357_k127_1724198_15	293613.A1E_02785	4.173e-47	178.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,47FFK@766|Rickettsiales	766|Rickettsiales	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
SRR25158357_k127_1724198_9	293614.A1C_00885	2.941e-72	251.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,47FCM@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158357_k127_1724198_21	334545.CCMG01000015_gene1186	8.024e-19	93.0	COG0484@1|root,COG0484@2|Bacteria,1QX3M@1224|Proteobacteria,2TX7I@28211|Alphaproteobacteria,47FS2@766|Rickettsiales	766|Rickettsiales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
SRR25158357_k127_1724198_0	272951.rsib_orf442	1.66e-170	554.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2U258@28211|Alphaproteobacteria,47F16@766|Rickettsiales	766|Rickettsiales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
SRR25158357_k127_1724198_17	1144888.CM001467_gene1433	3.22e-45	166.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,47FCR@766|Rickettsiales	766|Rickettsiales	C	Ferredoxin	fdxB	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
SRR25158357_k127_1724198_14	1340493.JNIF01000003_gene4766	7.972e-53	192.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	rutE	GO:0000166,GO:0003674,GO:0005488,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0010181,GO:0017144,GO:0019740,GO:0019860,GO:0032553,GO:0033554,GO:0034641,GO:0036094,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_1083,iECO103_1326.ECO103_1054,iG2583_1286.G2583_1241	Nitroreductase
SRR25158357_k127_1724198_5	391896.A1I_01650	1.851e-99	329.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,47F0G@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158357_k127_1724198_10	1144888.CM001467_gene1510	2.921e-71	245.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,47FAI@766|Rickettsiales	766|Rickettsiales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158357_k127_1724198_13	336407.RBE_0164	6.572e-55	202.0	COG0803@1|root,COG0803@2|Bacteria,1PU9R@1224|Proteobacteria,2V611@28211|Alphaproteobacteria,47GH0@766|Rickettsiales	766|Rickettsiales	P	Zinc-uptake complex component A periplasmic	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158357_k127_1724198_6	336407.RBE_0165	1.308e-98	335.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,47F9S@766|Rickettsiales	766|Rickettsiales	H	COG0617 tRNA nucleotidyltransferase poly(A) polymerase	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
SRR25158357_k127_1724198_16	1528098.NOVO_08220	1.362e-45	190.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2TV1B@28211|Alphaproteobacteria,47FNU@766|Rickettsiales	766|Rickettsiales	N	flagellar hook-associated protein	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
SRR25158357_k127_1724198_4	86106.I862_03620	2.093e-102	344.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria,47F13@766|Rickettsiales	766|Rickettsiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
SRR25158357_k127_1724198_8	334545.CCMG01000018_gene1459	4.804e-79	270.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,47F7G@766|Rickettsiales	766|Rickettsiales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158357_k127_1724198_12	1144888.CM001467_gene1417	3.906e-66	229.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,47FCE@766|Rickettsiales	766|Rickettsiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158357_k127_1724198_2	336407.RBE_0561	4.614e-122	398.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,47F1P@766|Rickettsiales	766|Rickettsiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158357_k127_1724198_22	1163617.SCD_n01013	6.681e-09	57.0	COG1487@1|root,COG1487@2|Bacteria,1MZCD@1224|Proteobacteria,2VXRA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158357_k127_1724198_3	357244.OTBS_0470	2.426e-106	360.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,47F88@766|Rickettsiales	766|Rickettsiales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158357_k127_1724198_19	1040987.AZUY01000005_gene1993	7.617e-29	123.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TRHY@28211|Alphaproteobacteria,43HBQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158357_k127_1724198_11	334545.CCMG01000011_gene857	8.718e-68	233.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47F3Y@766|Rickettsiales	766|Rickettsiales	EGP	Major facilitator	proP6	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158357_k127_1728908_1	336407.RBE_1012	1.112e-105	346.0	COG3504@1|root,COG3504@2|Bacteria,1MVEF@1224|Proteobacteria,2U90J@28211|Alphaproteobacteria,47F7Y@766|Rickettsiales	766|Rickettsiales	U	Type IV secretory pathway, VirB9 components	trbG	-	-	ko:K03204	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagX
SRR25158357_k127_1728908_4	1177928.TH2_04020	6.419e-42	163.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,2U6DE@28211|Alphaproteobacteria,2JRU9@204441|Rhodospirillales	204441|Rhodospirillales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158357_k127_1728908_5	86106.I862_04445	2.361e-10	63.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,2VB37@28211|Alphaproteobacteria,47FTM@766|Rickettsiales	766|Rickettsiales	J	structural constituent of ribosome	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158357_k127_1728908_0	272947.RP241	1.695e-106	349.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,47F58@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158357_k127_1728908_2	391896.A1I_03815	1.891e-93	313.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,47F9G@766|Rickettsiales	766|Rickettsiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
SRR25158357_k127_1728908_3	293614.A1C_01775	4.615e-46	175.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,47FAA@766|Rickettsiales	766|Rickettsiales	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158357_k127_1736543_27	336407.RBE_0808	9.551e-05	44.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2TVJN@28211|Alphaproteobacteria,47FAQ@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF1705)	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
SRR25158357_k127_1736543_9	391896.A1I_07565	3.679e-137	466.0	COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria,47FHN@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
SRR25158357_k127_1736543_8	391896.A1I_07570	8.425e-140	456.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,47EXH@766|Rickettsiales	766|Rickettsiales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	udg	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158357_k127_1736543_0	452659.RrIowa_1419	0.0	1413.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,47EWP@766|Rickettsiales	766|Rickettsiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158357_k127_1736543_2	244582.JQAK01000001_gene2142	1.721e-295	915.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,47EUE@766|Rickettsiales	766|Rickettsiales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158357_k127_1736543_22	336407.RBE_0326	1.352e-27	117.0	COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2UFK9@28211|Alphaproteobacteria,47FNE@766|Rickettsiales	766|Rickettsiales	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158357_k127_1736543_13	293613.A1E_03425	6.706e-84	286.0	COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2TU8Z@28211|Alphaproteobacteria,47FK0@766|Rickettsiales	766|Rickettsiales	P	COG0672 High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158357_k127_1736543_16	1105110.MC5_05140	1.037e-50	185.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,47FQ6@766|Rickettsiales	766|Rickettsiales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
SRR25158357_k127_1736543_21	257363.RT0452	9.612e-28	115.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1736543_10	334545.CCMG01000007_gene242	1.443e-132	453.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1736543_25	1230476.C207_06965	1.738e-08	62.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2U718@28211|Alphaproteobacteria,3JY4Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Response regulator receiver	MA20_29145	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158357_k127_1736543_26	981369.JQMJ01000004_gene1631	5.213e-07	60.0	COG0500@1|root,COG2226@2|Bacteria,2I4NS@201174|Actinobacteria,2NHM5@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158357_k127_1736543_12	391896.A1I_00770	1.524e-88	301.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,47FET@766|Rickettsiales	766|Rickettsiales	J	ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158357_k127_1736543_4	334545.CCMG01000014_gene998	1.375e-190	607.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47EX6@766|Rickettsiales	766|Rickettsiales	C	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlc1	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006862,GO:0008150,GO:0015711,GO:0015748,GO:0015865,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051503,GO:0071702,GO:0071705,GO:0071944,GO:1901264	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
SRR25158357_k127_1736543_11	398767.Glov_2140	7.489e-103	336.0	COG2184@1|root,COG2184@2|Bacteria,1R72A@1224|Proteobacteria,43B8I@68525|delta/epsilon subdivisions,2WT3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Fic/DOC family	-	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
SRR25158357_k127_1736543_20	755731.Clo1100_3983	4.014e-28	119.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,36I0G@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158357_k127_1736543_3	315456.RF_0059	8.417e-200	631.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,47F2W@766|Rickettsiales	766|Rickettsiales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158357_k127_1736543_19	272951.rsib_orf763	5.568e-39	149.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,47FFY@766|Rickettsiales	766|Rickettsiales	C	COG3288 NAD NADP transhydrogenase alpha subunit	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158357_k127_1736543_7	452659.RrIowa_1559	6.572e-147	473.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,47F1Z@766|Rickettsiales	766|Rickettsiales	C	COG3288 NAD NADP transhydrogenase alpha subunit	pntAA	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158357_k127_1736543_17	272947.RP864	1.008e-46	175.0	COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,47FKK@766|Rickettsiales	766|Rickettsiales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
SRR25158357_k127_1736543_5	334545.CCMG01000011_gene870	3.075e-157	512.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,47EXT@766|Rickettsiales	766|Rickettsiales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
SRR25158357_k127_1736543_23	391896.A1I_00660	7.342e-27	112.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,47FQK@766|Rickettsiales	766|Rickettsiales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158357_k127_1736543_15	391896.A1I_01060	1.609e-77	263.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,47F94@766|Rickettsiales	766|Rickettsiales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158357_k127_1736543_1	391896.A1I_01830	0.0	1137.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,47F2F@766|Rickettsiales	766|Rickettsiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158357_k127_1736543_6	391896.A1I_01835	4.384e-156	502.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,47EV0@766|Rickettsiales	766|Rickettsiales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158357_k127_1736543_14	86106.I862_06315	1.858e-80	281.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2TS4G@28211|Alphaproteobacteria,47F7D@766|Rickettsiales	766|Rickettsiales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SRR25158357_k127_1736543_18	86106.I862_05715	1.365e-41	157.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,47FHB@766|Rickettsiales	766|Rickettsiales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158357_k127_1756168_3	272947.RP026	4.449e-65	226.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,47FC4@766|Rickettsiales	766|Rickettsiales	K	to M. xanthus CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158357_k127_1756168_0	315456.RF_1307	1.088e-260	823.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,47EW9@766|Rickettsiales	766|Rickettsiales	D	Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity)	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158357_k127_1756168_4	471874.PROSTU_02027	6.708e-15	79.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria,3ZA5K@586|Providencia	1236|Gammaproteobacteria	S	Psort location CytoplasmicMembrane, score 9.46	yhaH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF805
SRR25158357_k127_1756168_2	391896.A1I_02895	8.533e-70	248.0	28IN0@1|root,2Z8NG@2|Bacteria,1NKGF@1224|Proteobacteria	1224|Proteobacteria	H	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	2.4.1.152,2.4.1.65	ko:K20151	-	-	-	-	ko00000,ko01000,ko01003	-	GT10	-	Glyco_transf_10
SRR25158357_k127_1756168_1	334545.CCMG01000008_gene749	2.07e-238	762.0	COG3451@1|root,COG3451@2|Bacteria,1NR16@1224|Proteobacteria,2UP6P@28211|Alphaproteobacteria,47FYH@766|Rickettsiales	766|Rickettsiales	U	COG3451 Type IV secretory pathway, VirB4 components	virB4-2	-	-	ko:K03199	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagE_TrbE_VirB
SRR25158357_k127_1761684_4	336407.RBE_1308	9.683e-23	98.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,47F0T@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158357_k127_1761684_3	1280949.HAD_12509	5.641e-45	167.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,43XNC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158357_k127_1761684_1	315456.RF_0454	2.962e-273	857.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,47ETA@766|Rickettsiales	766|Rickettsiales	E	Protease II	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158357_k127_1761684_0	315456.RF_1353	0.0	1193.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,47EUQ@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158357_k127_1787058_2	1528098.NOVO_04045	9.772e-63	220.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2TRHN@28211|Alphaproteobacteria,47FDY@766|Rickettsiales	766|Rickettsiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
SRR25158357_k127_1787058_3	858215.Thexy_1316	6.673e-17	83.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia,42GTH@68295|Thermoanaerobacterales	186801|Clostridia	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
SRR25158357_k127_1787058_0	452659.RrIowa_0482	0.0	1146.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,47EZJ@766|Rickettsiales	766|Rickettsiales	L	This protein is involved in the repair of mismatches in DNA	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158357_k127_1787058_1	334545.CCMG01000002_gene157	6.833e-149	483.0	COG0500@1|root,COG2226@2|Bacteria,1QWA7@1224|Proteobacteria,2TWUC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_31
SRR25158357_k127_1797476_1	297246.lpp1661	1.841e-84	286.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1JCGZ@118969|Legionellales	118969|Legionellales	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
SRR25158357_k127_1797476_3	163164.WD_1205	2.168e-40	153.0	COG3543@1|root,COG3543@2|Bacteria,1RI03@1224|Proteobacteria,2U9SV@28211|Alphaproteobacteria,47FNG@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
SRR25158357_k127_1797476_4	570417.WP0956	1.136e-30	128.0	COG1268@1|root,COG1268@2|Bacteria,1RH78@1224|Proteobacteria,2UE05@28211|Alphaproteobacteria,47FIJ@766|Rickettsiales	766|Rickettsiales	S	BioY family	bioY2	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158357_k127_1797476_0	336407.RBE_0342	8.701e-179	593.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1797476_2	391896.A1I_06065	7.371e-51	190.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1806339_8	95619.PM1_0201885	1.417e-24	104.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158357_k127_1806339_0	315456.RF_1060	4.425e-315	975.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,47F1Q@766|Rickettsiales	766|Rickettsiales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158357_k127_1806339_2	1144888.CM001467_gene1454	3.006e-122	396.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,47F0J@766|Rickettsiales	766|Rickettsiales	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158357_k127_1806339_6	293613.A1E_04045	2.084e-75	257.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2U6ZT@28211|Alphaproteobacteria,47FBJ@766|Rickettsiales	766|Rickettsiales	O	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
SRR25158357_k127_1806339_4	1105110.MC5_04550	3.768e-99	329.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,47F3D@766|Rickettsiales	766|Rickettsiales	S	COG1137 ABC-type (unclassified) transport system, ATPase component	abcT2	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158357_k127_1806339_11	709797.CSIRO_0856	0.0001288	50.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,3JTRX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	OstA-like protein	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRR25158357_k127_1806339_10	336407.RBE_0775	5.756e-19	94.0	COG5375@1|root,COG5375@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SRR25158357_k127_1806339_3	336407.RBE_0774	4.198e-106	352.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,47F46@766|Rickettsiales	766|Rickettsiales	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
SRR25158357_k127_1806339_5	391896.A1I_02500	9.888e-99	333.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,47FAG@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158357_k127_1806339_1	315456.RF_0635	6.331e-155	498.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,47EZX@766|Rickettsiales	766|Rickettsiales	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158357_k127_1806339_9	1333998.M2A_1378	7.077e-21	95.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,4BPX4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158357_k127_1813419_0	334545.CCMG01000008_gene738	3.707e-288	910.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,47F10@766|Rickettsiales	766|Rickettsiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158357_k127_1813419_4	391896.A1I_03235	2.492e-71	248.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,47EW1@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
SRR25158357_k127_1813419_2	391896.A1I_03240	4.887e-103	340.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,47ET9@766|Rickettsiales	766|Rickettsiales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158357_k127_1813419_3	315456.RF_1194	9.843e-90	304.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,47F9A@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158357_k127_1813419_1	334545.CCMG01000008_gene697	1.962e-105	353.0	COG0683@1|root,COG0683@2|Bacteria,1QURG@1224|Proteobacteria,2TS62@28211|Alphaproteobacteria,47FK2@766|Rickettsiales	766|Rickettsiales	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158357_k127_1823263_5	391896.A1I_03340	7.059e-110	388.0	COG2887@1|root,COG2887@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,47F0W@766|Rickettsiales	766|Rickettsiales	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
SRR25158357_k127_1823263_10	293614.A1C_03245	2.779e-18	90.0	COG1238@1|root,COG1238@2|Bacteria,1Q7HG@1224|Proteobacteria,2VDNU@28211|Alphaproteobacteria,47GJN@766|Rickettsiales	766|Rickettsiales	I	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1823263_4	519989.ECTPHS_09403	1.793e-126	419.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR25158357_k127_1823263_1	336407.RBE_0351	1.169e-185	593.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,47F0A@766|Rickettsiales	766|Rickettsiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158357_k127_1823263_6	1144888.CM001467_gene1523	6.046e-99	329.0	COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,47F75@766|Rickettsiales	766|Rickettsiales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MipZ
SRR25158357_k127_1823263_3	293614.A1C_05400	4.094e-131	431.0	COG1322@1|root,COG1322@2|Bacteria,1QC6Y@1224|Proteobacteria,2U7V0@28211|Alphaproteobacteria,47F2T@766|Rickettsiales	766|Rickettsiales	S	DNA recombination protein RmuC homolog	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158357_k127_1823263_2	391896.A1I_03790	6.374e-182	579.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,47F0K@766|Rickettsiales	766|Rickettsiales	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SRR25158357_k127_1823263_8	190650.CC_2463	1.649e-32	131.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,2KGFJ@204458|Caulobacterales	204458|Caulobacterales	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158357_k127_1823263_9	1105110.MC5_01050	7.308e-20	96.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,47FG9@766|Rickettsiales	766|Rickettsiales	L	COG2927 DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
SRR25158357_k127_1823263_11	1528106.JRJE01000026_gene38	5.698e-14	82.0	COG1216@1|root,COG1216@2|Bacteria,1N1SC@1224|Proteobacteria	1224|Proteobacteria	S	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158357_k127_1823263_7	336407.RBE_0591	1.055e-41	154.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,47FG0@766|Rickettsiales	766|Rickettsiales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158357_k127_1823263_0	1528098.NOVO_08195	1.526e-248	777.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,47EV8@766|Rickettsiales	766|Rickettsiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158357_k127_1830354_1	297246.lpp0661	1.804e-84	295.0	COG2271@1|root,COG2271@2|Bacteria,1RD3X@1224|Proteobacteria,1T6K4@1236|Gammaproteobacteria,1JDH4@118969|Legionellales	118969|Legionellales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158357_k127_1830354_0	315456.RF_0700	6.355e-127	414.0	COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2TSKU@28211|Alphaproteobacteria,47EYP@766|Rickettsiales	766|Rickettsiales	C	reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158357_k127_1830354_2	400682.PAC_15722938	0.0004856	52.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta	33154|Opisthokonta	M	protein localization to T-tubule	-	-	-	ko:K10380,ko:K15503,ko:K21440	ko04624,ko05205,map04624,map05205	-	-	-	ko00000,ko00001,ko01009,ko03400,ko04131,ko04812	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158357_k127_1850676_1	272947.RP283	2.287e-57	208.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria,47F9K@766|Rickettsiales	766|Rickettsiales	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M
SRR25158357_k127_1850676_2	336407.RBE_1022	2.453e-55	214.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,2TSJC@28211|Alphaproteobacteria,47FNZ@766|Rickettsiales	766|Rickettsiales	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	nuoL3	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158357_k127_1850676_3	192875.XP_004345490.1	1.693e-25	119.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38EHF@33154|Opisthokonta	33154|Opisthokonta	DTZ	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_6
SRR25158357_k127_1850676_0	336407.RBE_0794	6.231e-251	785.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,47EW0@766|Rickettsiales	766|Rickettsiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158357_k127_1856830_21	439235.Dalk_0995	7.514e-20	92.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,42VB5@68525|delta/epsilon subdivisions,2WRJD@28221|Deltaproteobacteria,2MKVP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM FlhB HrpN YscU SpaS Family	-	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
SRR25158357_k127_1856830_13	391896.A1I_07845	1.185e-61	218.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2UGK6@28211|Alphaproteobacteria,47FKW@766|Rickettsiales	766|Rickettsiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
SRR25158357_k127_1856830_17	742727.HMPREF9447_00178	1.501e-34	136.0	COG1546@1|root,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,2FMFI@200643|Bacteroidia,4APD5@815|Bacteroidaceae	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158357_k127_1856830_1	272951.rsib_orf1298	1.89e-229	727.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,47ET4@766|Rickettsiales	766|Rickettsiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR25158357_k127_1856830_18	1528098.NOVO_07795	1.549e-29	127.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U7M5@28211|Alphaproteobacteria,47F7I@766|Rickettsiales	766|Rickettsiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158357_k127_1856830_22	1293054.HSACCH_02255	1.515e-10	66.0	COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,249J7@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158357_k127_1856830_7	1144888.CM001467_gene1169	2.072e-114	376.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,47F6H@766|Rickettsiales	766|Rickettsiales	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158357_k127_1856830_15	257363.RT0290	1.118e-46	171.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria,47FGR@766|Rickettsiales	766|Rickettsiales	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158357_k127_1856830_20	1528098.NOVO_05685	9.808e-23	108.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,47GT2@766|Rickettsiales	766|Rickettsiales	D	Peptidase family M23	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	Peptidase_M23
SRR25158357_k127_1856830_4	391896.A1I_05120	1.045e-124	408.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,47EXN@766|Rickettsiales	766|Rickettsiales	E	Threonine dehydratase	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158357_k127_1856830_0	336407.RBE_0797	0.0	1022.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,47EV7@766|Rickettsiales	766|Rickettsiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158357_k127_1856830_2	391896.A1I_06065	3.201e-168	563.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_1856830_11	315456.RF_0078	1.631e-72	255.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,47EZG@766|Rickettsiales	766|Rickettsiales	EF	Ribose-phosphate pyrophosphokinase	prsA	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
SRR25158357_k127_1856830_12	391896.A1I_06120	3.808e-64	227.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,47FPG@766|Rickettsiales	766|Rickettsiales	O	COG1214 Inactive homolog of metal-dependent proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
SRR25158357_k127_1856830_14	336407.RBE_1427	6.794e-59	208.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,47FE2@766|Rickettsiales	766|Rickettsiales	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
SRR25158357_k127_1856830_6	336407.RBE_1428	9.624e-115	379.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,47EZ6@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158357_k127_1856830_5	391896.A1I_07950	1.847e-123	404.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,47EW4@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158357_k127_1856830_8	257363.RT0001	7.724e-107	353.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2TT66@28211|Alphaproteobacteria,47G24@766|Rickettsiales	766|Rickettsiales	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
SRR25158357_k127_1856830_16	257363.RT0717	1.057e-42	163.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,47FKR@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158357_k127_1856830_9	315456.RF_0176	1.502e-89	300.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,47F82@766|Rickettsiales	766|Rickettsiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158357_k127_1856830_19	357244.OTBS_1540	1.625e-25	113.0	COG0212@1|root,COG0212@2|Bacteria,1Q756@1224|Proteobacteria,2VD9K@28211|Alphaproteobacteria,47FPR@766|Rickettsiales	766|Rickettsiales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158357_k127_1856830_23	1207063.P24_04075	1.147e-07	61.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2TUVR@28211|Alphaproteobacteria,2JSVA@204441|Rhodospirillales	204441|Rhodospirillales	S	membrane protein, required for colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
SRR25158357_k127_1856830_10	336407.RBE_0078	7.706e-77	264.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,47FAE@766|Rickettsiales	766|Rickettsiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158357_k127_1856830_3	272947.RP783	4.223e-135	437.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,47F37@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158357_k127_1866847_2	334545.CCMG01000008_gene688	2.287e-73	256.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,47FC1@766|Rickettsiales	766|Rickettsiales	S	COG1253 Hemolysins and related proteins containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
SRR25158357_k127_1866847_1	334545.CCMG01000012_gene948	4.903e-95	323.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,47F61@766|Rickettsiales	766|Rickettsiales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,SMC_N
SRR25158357_k127_1866847_0	336407.RBE_1309	7.01e-149	476.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,47EY3@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158357_k127_1866847_3	257363.RT0158	7.44e-34	136.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,47FPD@766|Rickettsiales	766|Rickettsiales	I	COG2867 oligoketide cyclase lipid transport protein	ratA	-	-	ko:K18588	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
SRR25158357_k127_1866847_4	1121015.N789_05155	1.989e-23	102.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158357_k127_1866903_2	1528098.NOVO_05275	1.489e-114	378.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2TRIV@28211|Alphaproteobacteria,47F0H@766|Rickettsiales	766|Rickettsiales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
SRR25158357_k127_1866903_1	1528098.NOVO_05280	1.004e-115	391.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2TR6J@28211|Alphaproteobacteria,47F49@766|Rickettsiales	766|Rickettsiales	NU	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
SRR25158357_k127_1866903_3	452659.RrIowa_1442	2.469e-34	134.0	COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,2UG15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1866903_0	1535287.JP74_16670	1.559e-233	737.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,3N66E@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158357_k127_1883202_5	227377.CBU_0110a	3.972e-07	54.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1883202_1	1144888.CM001467_gene960	5.308e-80	273.0	COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,47F9E@766|Rickettsiales	766|Rickettsiales	O	Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N_3
SRR25158357_k127_1883202_7	1278309.KB907099_gene2482	2.382e-05	51.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1XK8F@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158357_k127_1883202_4	402881.Plav_2924	1.104e-11	68.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,1JP7Y@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158357_k127_1883202_0	336407.RBE_0128	1.679e-135	437.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,47EVU@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158357_k127_1883202_3	293613.A1E_04955	3.839e-21	93.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,2UKBX@28211|Alphaproteobacteria,47FSZ@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158357_k127_1883202_2	334545.CCMG01000008_gene736	5.987e-36	141.0	COG2913@1|root,COG2913@2|Bacteria,1PSG5@1224|Proteobacteria,2VABF@28211|Alphaproteobacteria,47FSJ@766|Rickettsiales	766|Rickettsiales	J	SmpA / OmlA family	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
SRR25158357_k127_1883202_6	574966.KB898646_gene3048	2.182e-05	49.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,1XMBW@135619|Oceanospirillales	135619|Oceanospirillales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158357_k127_1892234_2	336407.RBE_0130	2.347e-89	306.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,47F8I@766|Rickettsiales	766|Rickettsiales	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR25158357_k127_1892234_1	272947.RP768	4.115e-172	547.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,47EYF@766|Rickettsiales	766|Rickettsiales	D	Rod shape-determining protein (MreB)	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158357_k127_1892234_4	293613.A1E_04930	3.211e-50	188.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,47FKG@766|Rickettsiales	766|Rickettsiales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158357_k127_1892234_6	1120959.ATXF01000008_gene473	0.0002121	54.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FMZN@85023|Microbacteriaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158357_k127_1892234_5	414684.RC1_1722	5.248e-14	78.0	2EA0K@1|root,33461@2|Bacteria,1NBGC@1224|Proteobacteria,2UGGB@28211|Alphaproteobacteria,2JUC2@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_1892234_3	293614.A1C_06735	3.151e-82	286.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,47FE4@766|Rickettsiales	766|Rickettsiales	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR25158357_k127_1892234_0	1105110.MC5_01425	5.272e-238	743.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,47F3M@766|Rickettsiales	766|Rickettsiales	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158357_k127_1910882_3	744980.TRICHSKD4_1448	3.089e-64	224.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158357_k127_1910882_2	257363.RT0073	1.319e-78	273.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,47F6R@766|Rickettsiales	766|Rickettsiales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158357_k127_1910882_1	334545.CCMG01000014_gene1003	1.27e-104	345.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,47EWD@766|Rickettsiales	766|Rickettsiales	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158357_k127_1910882_4	272947.RP057	2.562e-54	196.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,47FJ7@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158357_k127_1910882_0	334545.CCMG01000014_gene1001	2.319e-240	752.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,47F1A@766|Rickettsiales	766|Rickettsiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158357_k127_1914391_9	471854.Dfer_0837	1.582e-48	185.0	COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,4NNCW@976|Bacteroidetes,47Q96@768503|Cytophagia	976|Bacteroidetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SRR25158357_k127_1914391_10	334545.CCMG01000008_gene655	7.202e-41	155.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,47FIU@766|Rickettsiales	766|Rickettsiales	Q	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158357_k127_1914391_13	357244.OTBS_1583	9.66e-24	104.0	COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria,47FSF@766|Rickettsiales	766|Rickettsiales	C	NADH ubiquinone oxidoreductase 17.2 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	NDUFA12
SRR25158357_k127_1914391_8	1144888.CM001467_gene433	8.055e-57	201.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,47FDC@766|Rickettsiales	766|Rickettsiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158357_k127_1914391_12	86106.I862_06250	2.878e-29	123.0	COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,47FJ2@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
SRR25158357_k127_1914391_5	1144888.CM001467_gene966	2.566e-94	314.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,47EVQ@766|Rickettsiales	766|Rickettsiales	G	Class II Aldolase and Adducin N-terminal domain	addA	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158357_k127_1914391_1	391896.A1I_05205	2.651e-226	711.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,47EUA@766|Rickettsiales	766|Rickettsiales	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158357_k127_1914391_2	391896.A1I_05210	1.277e-190	604.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,47F04@766|Rickettsiales	766|Rickettsiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
SRR25158357_k127_1914391_7	1105110.MC5_05750	3.372e-81	273.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,47F57@766|Rickettsiales	766|Rickettsiales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158357_k127_1914391_14	272951.rsib_orf277	2.427e-23	103.0	2EM8M@1|root,33EXQ@2|Bacteria,1NNUH@1224|Proteobacteria,2UK6Q@28211|Alphaproteobacteria,47FSN@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628
SRR25158357_k127_1914391_11	334545.CCMG01000017_gene1358	2.828e-35	137.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,47FGB@766|Rickettsiales	766|Rickettsiales	FG	Protein kinase C inhibitor 1	pkcI	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158357_k127_1914391_4	1528098.NOVO_08580	4.017e-110	365.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,47EUG@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158357_k127_1914391_0	293614.A1C_02345	1.997e-271	845.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,2TR17@28211|Alphaproteobacteria,47EWN@766|Rickettsiales	766|Rickettsiales	V	alkaline protease secretion ATP-binding protein	aprD	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_1914391_6	334545.CCMG01000017_gene1355	6.329e-86	294.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,47EZT@766|Rickettsiales	766|Rickettsiales	M	Secretion protein	aprE	-	-	ko:K02022,ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
SRR25158357_k127_1914391_16	1236542.BALM01000014_gene1232	5.834e-05	50.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,2Q94K@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
SRR25158357_k127_1914391_3	244582.JQAK01000004_gene152	2.133e-127	421.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2TQVA@28211|Alphaproteobacteria,47GE0@766|Rickettsiales	766|Rickettsiales	U	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
SRR25158357_k127_1922226_5	391600.ABRU01000025_gene1087	4.47e-10	70.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2TSF2@28211|Alphaproteobacteria,2KFGD@204458|Caulobacterales	204458|Caulobacterales	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
SRR25158357_k127_1922226_1	315456.RF_0529	7.227e-189	599.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,47F2V@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158357_k127_1922226_2	315456.RF_0762	4.752e-163	520.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,47EZP@766|Rickettsiales	766|Rickettsiales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158357_k127_1922226_0	1528098.NOVO_06880	4.489e-315	987.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,47F2B@766|Rickettsiales	766|Rickettsiales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158357_k127_1922226_3	349106.PsycPRwf_0678	2.283e-55	201.0	COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,1S3TT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
SRR25158357_k127_1922226_4	357244.OTBS_0312	2.752e-14	74.0	COG3202@1|root,COG3202@2|Bacteria,1RCHN@1224|Proteobacteria,2VFB2@28211|Alphaproteobacteria,47G3X@766|Rickettsiales	766|Rickettsiales	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlc4	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015931,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
SRR25158357_k127_1939867_5	1399147.P618_200033	2.385e-93	314.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,47FUT@766|Rickettsiales	766|Rickettsiales	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158357_k127_1939867_7	452659.RrIowa_0399	2.793e-19	90.0	COG0271@1|root,COG0271@2|Bacteria,1Q75X@1224|Proteobacteria,2VDAA@28211|Alphaproteobacteria,47FSH@766|Rickettsiales	766|Rickettsiales	T	Belongs to the BolA IbaG family	bolA1	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
SRR25158357_k127_1939867_3	391896.A1I_03835	1.018e-101	344.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,2TT4R@28211|Alphaproteobacteria,47F7K@766|Rickettsiales	766|Rickettsiales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SRR25158357_k127_1939867_1	1528098.NOVO_07225	1.615e-183	583.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2TRXU@28211|Alphaproteobacteria,47EUF@766|Rickettsiales	766|Rickettsiales	NU	ATP synthase alpha/beta family, nucleotide-binding domain	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158357_k127_1939867_2	1144888.CM001467_gene205	1.479e-159	505.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2TS2N@28211|Alphaproteobacteria,47EVV@766|Rickettsiales	766|Rickettsiales	J	glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRR25158357_k127_1939867_0	334545.CCMG01000011_gene854	1.791e-209	671.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,47F1H@766|Rickettsiales	766|Rickettsiales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRR25158357_k127_1939867_4	391896.A1I_00760	7.367e-98	329.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,47F5A@766|Rickettsiales	766|Rickettsiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158357_k127_1939867_8	616991.JPOO01000003_gene1942	2.068e-11	67.0	COG4095@1|root,COG4095@2|Bacteria,4NUQW@976|Bacteroidetes,1I5DC@117743|Flavobacteriia	976|Bacteroidetes	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
SRR25158357_k127_1939867_6	336407.RBE_0184	2.294e-31	136.0	COG4625@1|root,COG4625@2|Bacteria,1PHUK@1224|Proteobacteria,2U1YI@28211|Alphaproteobacteria,47GPX@766|Rickettsiales	766|Rickettsiales	S	protein with a C-terminal OMP (outer membrane protein) domain	ompB	GO:0005575,GO:0005576,GO:0005623,GO:0009986,GO:0044464	-	-	-	-	-	-	-	-	-	-	Autotransporter,rOmpB
SRR25158357_k127_1943003_3	272951.rsib_orf1143	3.804e-141	452.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,47EWY@766|Rickettsiales	766|Rickettsiales	I	Propionyl-CoA carboxylase alpha	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158357_k127_1943003_0	336407.RBE_0467	4.623e-290	895.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,47EV6@766|Rickettsiales	766|Rickettsiales	I	propionyl-CoA carboxylase beta	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158357_k127_1943003_1	336407.RBE_0685	6.052e-277	868.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,47EUH@766|Rickettsiales	766|Rickettsiales	L	Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity)	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158357_k127_1943003_2	91604.ID47_05710	7.909e-167	554.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1MWRF@1224|Proteobacteria,2U9VQ@28211|Alphaproteobacteria,47F2N@766|Rickettsiales	766|Rickettsiales	Q	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_5,GerE,NB-ARC,TPR_12,TPR_2,TPR_7,TPR_8
SRR25158357_k127_1943003_6	244581.IM40_08560	1.189e-29	128.0	COG0457@1|root,COG0457@2|Bacteria,1MWRF@1224|Proteobacteria,2U9VQ@28211|Alphaproteobacteria,47FXI@766|Rickettsiales	766|Rickettsiales	S	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,NB-ARC,TPR_12,TPR_7
SRR25158357_k127_1943003_5	315456.RF_1016	6.748e-35	140.0	COG2825@1|root,COG2825@2|Bacteria,1NAN5@1224|Proteobacteria,2UGJF@28211|Alphaproteobacteria,47FPI@766|Rickettsiales	766|Rickettsiales	M	COG2825 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
SRR25158357_k127_1943003_4	1105110.MC5_07030	2.309e-111	364.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,47EU7@766|Rickettsiales	766|Rickettsiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158357_k127_195413_2	865861.AZSU01000006_gene1186	3.818e-75	258.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	agcS_1	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
SRR25158357_k127_195413_5	631362.Thi970DRAFT_04163	8.055e-10	66.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WXP6@135613|Chromatiales	135613|Chromatiales	O	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158357_k127_195413_4	94624.Bpet3209	2.165e-46	177.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2VREA@28216|Betaproteobacteria,3T3G3@506|Alcaligenaceae	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158357_k127_195413_0	336407.RBE_1183	3.764e-237	737.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria,47EVE@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158357_k127_195413_3	1144888.CM001467_gene1180	9.716e-69	236.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,47F8V@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
SRR25158357_k127_195413_1	391896.A1I_05790	6.382e-76	256.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,47ET3@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158357_k127_1957377_2	452659.RrIowa_1236	2.075e-19	88.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,47FAR@766|Rickettsiales	766|Rickettsiales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158357_k127_1957377_0	391896.A1I_06800	2.656e-112	368.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,47F6W@766|Rickettsiales	766|Rickettsiales	L	Exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158357_k127_1957377_1	336407.RBE_0025	9.53e-73	249.0	COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,47FAB@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09987	-	-	-	-	ko00000	-	-	-	DUF1013
SRR25158357_k127_1957377_4	754477.Q7C_258	1.609e-11	75.0	2A25B@1|root,30QFQ@2|Bacteria,1RDBY@1224|Proteobacteria,1SBXH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protochlamydia outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Pom
SRR25158357_k127_1957377_3	1144888.CM001467_gene1577	5.422e-19	86.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,47FRK@766|Rickettsiales	766|Rickettsiales	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158357_k127_197599_0	269796.Rru_A2109	7.612e-220	706.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2JPMS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158357_k127_197599_5	357244.OTBS_0673	3.288e-17	85.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,47FKH@766|Rickettsiales	766|Rickettsiales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158357_k127_197599_2	336407.RBE_0411	5.105e-98	323.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,47F4C@766|Rickettsiales	766|Rickettsiales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158357_k127_197599_1	315456.RF_0219	2.192e-181	576.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,47F36@766|Rickettsiales	766|Rickettsiales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158357_k127_197599_3	86106.I862_00685	5.488e-59	216.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,47FEG@766|Rickettsiales	766|Rickettsiales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158357_k127_197599_4	1122135.KB893134_gene3434	1.099e-43	168.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	MA20_24100	-	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
SRR25158357_k127_203831_2	336407.RBE_0851	6.162e-117	391.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,47ETS@766|Rickettsiales	766|Rickettsiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158357_k127_203831_4	336407.RBE_0850	8.267e-14	75.0	COG2938@1|root,COG2938@2|Bacteria,1Q75I@1224|Proteobacteria,2VD9X@28211|Alphaproteobacteria,47FRC@766|Rickettsiales	766|Rickettsiales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
SRR25158357_k127_203831_0	293613.A1E_01825	8.011e-204	643.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,47EXY@766|Rickettsiales	766|Rickettsiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158357_k127_203831_1	336407.RBE_0656	1.295e-130	427.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,47F39@766|Rickettsiales	766|Rickettsiales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158357_k127_203831_3	293614.A1C_00410	4.876e-47	171.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,47FA3@766|Rickettsiales	766|Rickettsiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158357_k127_228088_7	293614.A1C_03325	4.61e-52	187.0	COG0679@1|root,COG0679@2|Bacteria,1RDRQ@1224|Proteobacteria,2U92D@28211|Alphaproteobacteria,47FA8@766|Rickettsiales	766|Rickettsiales	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158357_k127_228088_1	391896.A1I_05480	3.093e-148	474.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,47EZ4@766|Rickettsiales	766|Rickettsiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158357_k127_228088_0	315456.RF_0860	2.834e-204	645.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,47F12@766|Rickettsiales	766|Rickettsiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158357_k127_228088_5	1150626.PHAMO_220062	1.548e-65	237.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JPAW@204441|Rhodospirillales	204441|Rhodospirillales	G	Glycosyl hydrolase family 3 N terminal domain	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158357_k127_228088_3	315456.RF_0741	4.955e-92	307.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,47F6P@766|Rickettsiales	766|Rickettsiales	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158357_k127_228088_2	1105110.MC5_04120	2.076e-100	335.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,47F8J@766|Rickettsiales	766|Rickettsiales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158357_k127_228088_4	315456.RF_0816	1.716e-70	249.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U2WH@28211|Alphaproteobacteria,47GPS@766|Rickettsiales	766|Rickettsiales	V	LD-carboxypeptidase	mccF2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
SRR25158357_k127_228088_6	357244.OTBS_1228	1.192e-55	196.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,47EUT@766|Rickettsiales	766|Rickettsiales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158357_k127_26055_9	340177.Cag_0616	0.000302	48.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3_2,CHU_C,Flg_new,LRR_5
SRR25158357_k127_26055_4	391896.A1I_05955	1.691e-67	238.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,2U5B7@28211|Alphaproteobacteria,47FE6@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR25158357_k127_26055_3	315456.RF_0006	3.405e-94	315.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,47ETJ@766|Rickettsiales	766|Rickettsiales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158357_k127_26055_6	336407.RBE_1188	2.394e-59	208.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,47FD7@766|Rickettsiales	766|Rickettsiales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158357_k127_26055_2	336407.RBE_1189	8.174e-124	406.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,47F51@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158357_k127_26055_7	272947.RP470	1.023e-25	111.0	COG5622@1|root,COG5622@2|Bacteria,1NHJD@1224|Proteobacteria,2UMR9@28211|Alphaproteobacteria,47FRH@766|Rickettsiales	766|Rickettsiales	N	COG5622 Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
SRR25158357_k127_26055_5	272951.rsib_orf383	4.091e-67	231.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2U7GI@28211|Alphaproteobacteria,47FC8@766|Rickettsiales	766|Rickettsiales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
SRR25158357_k127_26055_8	1415780.JPOG01000001_gene2848	1.229e-12	79.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1XAQ5@135614|Xanthomonadales	135614|Xanthomonadales	S	Divergent polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_2
SRR25158357_k127_26055_1	293614.A1C_01690	2.701e-142	465.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,47F3J@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158357_k127_26055_0	336407.RBE_0230	2.582e-229	722.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,47F38@766|Rickettsiales	766|Rickettsiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158357_k127_278066_5	1105110.MC5_02440	1.011e-66	231.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR25158357_k127_278066_4	391896.A1I_02585	9.227e-84	283.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158357_k127_278066_1	244581.IM40_02835	9.277e-140	452.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,47EVI@766|Rickettsiales	766|Rickettsiales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158357_k127_278066_3	391896.A1I_02655	5.26e-117	391.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,47F18@766|Rickettsiales	766|Rickettsiales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158357_k127_278066_2	336407.RBE_0852	7.273e-138	453.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,47ESZ@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158357_k127_278066_0	293614.A1C_04395	3.081e-197	629.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,47EZH@766|Rickettsiales	766|Rickettsiales	M	Cell division protein FtsI penicillin-binding protein 2	pbpA2	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158357_k127_291153_0	1528098.NOVO_03350	6.965e-264	830.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,47EV3@766|Rickettsiales	766|Rickettsiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158357_k127_291153_10	334545.CCMG01000018_gene1466	5.344e-92	308.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,2V6AK@28211|Alphaproteobacteria,47F4Y@766|Rickettsiales	766|Rickettsiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158357_k127_291153_21	244582.JQAK01000003_gene454	5.254e-09	61.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,2V6AK@28211|Alphaproteobacteria,47F4Y@766|Rickettsiales	766|Rickettsiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158357_k127_291153_14	315456.RF_0996	5.089e-76	261.0	COG2173@1|root,COG2173@2|Bacteria,1RENK@1224|Proteobacteria,2TRK8@28211|Alphaproteobacteria,47F8Z@766|Rickettsiales	766|Rickettsiales	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158357_k127_291153_5	227377.CBU_0503	2.406e-147	473.0	COG0174@1|root,COG0174@2|Bacteria,1NZU7@1224|Proteobacteria	1224|Proteobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158357_k127_291153_7	293613.A1E_04675	5.077e-106	389.0	COG4625@1|root,COG4625@2|Bacteria,1PHUK@1224|Proteobacteria,2U1YI@28211|Alphaproteobacteria,47GPX@766|Rickettsiales	766|Rickettsiales	S	protein with a C-terminal OMP (outer membrane protein) domain	ompB	GO:0005575,GO:0005576,GO:0005623,GO:0009986,GO:0044464	-	-	-	-	-	-	-	-	-	-	Autotransporter,rOmpB
SRR25158357_k127_291153_20	1123366.TH3_06255	2.974e-27	113.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,2JT8F@204441|Rhodospirillales	204441|Rhodospirillales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158357_k127_291153_15	336407.RBE_0179	2.62e-58	205.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,47FEP@766|Rickettsiales	766|Rickettsiales	O	bacterioferritin comigratory protein	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158357_k127_291153_3	293614.A1C_02985	9.864e-187	604.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,47EZR@766|Rickettsiales	766|Rickettsiales	M	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_8
SRR25158357_k127_291153_8	315456.RF_0171	3.221e-104	347.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,47EZI@766|Rickettsiales	766|Rickettsiales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158357_k127_291153_2	570952.ATVH01000018_gene3195	1.897e-199	640.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,2JPG1@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	cbbT	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158357_k127_291153_19	293613.A1E_02320	1.571e-32	138.0	28RCN@1|root,2ZDS1@2|Bacteria,1NGBU@1224|Proteobacteria,2V651@28211|Alphaproteobacteria,47GJT@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
SRR25158357_k127_291153_4	760192.Halhy_0884	1.854e-157	507.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1IV2Q@117747|Sphingobacteriia	976|Bacteroidetes	H	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158357_k127_291153_13	400668.Mmwyl1_1157	2.449e-80	285.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIJV@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
SRR25158357_k127_291153_18	334545.CCMG01000008_gene701	1.008e-36	139.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,47FKP@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158357_k127_291153_17	1144888.CM001467_gene389	1.923e-47	171.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,47FK1@766|Rickettsiales	766|Rickettsiales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158357_k127_291153_11	1089552.KI911559_gene1716	1.666e-83	284.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2JQ66@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158357_k127_291153_6	391896.A1I_00850	1.057e-109	360.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,47F1E@766|Rickettsiales	766|Rickettsiales	Q	ABC transporter, permease protein	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158357_k127_291153_9	1144888.CM001467_gene1582	1.282e-103	347.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,47F2Y@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158357_k127_291153_16	1380391.JIAS01000011_gene4931	4.923e-51	186.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,2JSGX@204441|Rhodospirillales	204441|Rhodospirillales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158357_k127_291153_1	1528098.NOVO_01015	1.909e-205	654.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,47EYS@766|Rickettsiales	766|Rickettsiales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
SRR25158357_k127_344019_0	1089552.KI911559_gene2618	1.176e-111	364.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,2JPF5@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	-	-	ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158357_k127_344019_7	293613.A1E_00325	6.57e-15	81.0	COG3203@1|root,COG3203@2|Bacteria,1NDGJ@1224|Proteobacteria,2UJ18@28211|Alphaproteobacteria,47FQ1@766|Rickettsiales	766|Rickettsiales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
SRR25158357_k127_344019_8	272951.rsib_orf613	9.196e-13	78.0	COG3203@1|root,COG3203@2|Bacteria,1NDGJ@1224|Proteobacteria,2UJ18@28211|Alphaproteobacteria,47FQ1@766|Rickettsiales	766|Rickettsiales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
SRR25158357_k127_344019_5	336407.RBE_1296	9.163e-55	196.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,47FFF@766|Rickettsiales	766|Rickettsiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
SRR25158357_k127_344019_2	336407.RBE_1297	3.626e-94	311.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2TSDM@28211|Alphaproteobacteria,47F3H@766|Rickettsiales	766|Rickettsiales	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158357_k127_344019_1	1105110.MC5_00735	5.664e-95	327.0	COG3203@1|root,COG3203@2|Bacteria,1NDGJ@1224|Proteobacteria,2UJ18@28211|Alphaproteobacteria,47FQ1@766|Rickettsiales	766|Rickettsiales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
SRR25158357_k127_344019_6	293613.A1E_03660	1.041e-23	108.0	COG4765@1|root,COG4765@2|Bacteria,1NQG4@1224|Proteobacteria,2UN4P@28211|Alphaproteobacteria,47GMI@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2155
SRR25158357_k127_344019_4	257363.RT0347	6.026e-69	248.0	COG3307@1|root,COG3307@2|Bacteria,1MZYX@1224|Proteobacteria,2UC2T@28211|Alphaproteobacteria,47FSC@766|Rickettsiales	766|Rickettsiales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158357_k127_344019_3	391896.A1I_02625	5.696e-78	269.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,47GQS@766|Rickettsiales	766|Rickettsiales	P	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRR25158357_k127_365956_10	1105110.MC5_04795	3.019e-63	228.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,47F7N@766|Rickettsiales	766|Rickettsiales	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158357_k127_365956_2	315456.RF_0646	3.858e-195	616.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,47EV2@766|Rickettsiales	766|Rickettsiales	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158357_k127_365956_12	1400524.KL370779_gene334	2.699e-37	151.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,4BQ2R@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158357_k127_365956_7	293613.A1E_05585	4.58e-123	405.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,47EZB@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158357_k127_365956_6	334545.CCMG01000011_gene845	6.542e-133	437.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,47F6I@766|Rickettsiales	766|Rickettsiales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158357_k127_365956_1	1230343.CANP01000031_gene2517	5.909e-229	722.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1JCHU@118969|Legionellales	118969|Legionellales	V	to multidrug resistance ABC transporter ATP-binding protein	abcT	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_365956_5	293613.A1E_04865	1.504e-169	537.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,47F00@766|Rickettsiales	766|Rickettsiales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158357_k127_365956_9	1220535.IMCC14465_12150	9.445e-75	260.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,4BPUR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158357_k127_365956_0	336407.RBE_0193	2.715e-263	829.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,47EZY@766|Rickettsiales	766|Rickettsiales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158357_k127_365956_4	452659.RrIowa_0863	8.471e-174	561.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,47EUI@766|Rickettsiales	766|Rickettsiales	E	COG0006 Xaa-Pro aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
SRR25158357_k127_365956_8	336407.RBE_0116	2.016e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,47EY4@766|Rickettsiales	766|Rickettsiales	IQ	dehydrogenases with different specificities (related to short-chain alcohol)	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158357_k127_365956_13	85643.Tmz1t_2325	6.207e-21	95.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KWX1@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158357_k127_365956_3	391896.A1I_07360	1.574e-174	556.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,47F0E@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158357_k127_365956_11	86106.I862_07345	4.77e-61	224.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2TVJN@28211|Alphaproteobacteria,47FAQ@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF1705)	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
SRR25158357_k127_376447_6	357244.OTBS_0444	2.429e-102	355.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,47ETW@766|Rickettsiales	766|Rickettsiales	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	recB	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158357_k127_376447_11	940282.CADQ01000066_gene644	2.489e-39	153.0	COG0607@1|root,COG0607@2|Bacteria,1RDIR@1224|Proteobacteria,2U820@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Protein of unknown function (DUF2892)	ygaP	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
SRR25158357_k127_376447_12	1161401.ASJA01000013_gene766	2.339e-36	141.0	297W1@1|root,2ZV2M@2|Bacteria,1QN4J@1224|Proteobacteria,2U80H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158357_k127_376447_3	334545.CCMG01000008_gene648	1.423e-189	596.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,47EYJ@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158357_k127_376447_5	391896.A1I_02360	3.466e-124	407.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158357_k127_376447_4	392499.Swit_1300	2.213e-136	440.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2K17I@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158357_k127_376447_1	336407.RBE_0737	3.029e-227	711.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,47F27@766|Rickettsiales	766|Rickettsiales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158357_k127_376447_2	452471.Aasi_0861	2.138e-199	632.0	COG2317@1|root,COG2317@2|Bacteria,4NK5Q@976|Bacteroidetes	976|Bacteroidetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158357_k127_376447_8	93220.LV28_13615	1.01e-82	281.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,2VJMW@28216|Betaproteobacteria,1K48M@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158357_k127_376447_7	1318628.MARLIPOL_06214	1.079e-85	292.0	COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,1RY3E@1236|Gammaproteobacteria,46430@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
SRR25158357_k127_376447_10	1547437.LL06_04950	7.803e-50	189.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,43JD6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158357_k127_376447_9	366394.Smed_3067	1.002e-68	245.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,4B7PX@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158357_k127_376447_0	1105110.MC5_02570	1.693e-227	715.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,47EWE@766|Rickettsiales	766|Rickettsiales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158357_k127_376447_13	293613.A1E_04535	8.313e-16	79.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,47F6Y@766|Rickettsiales	766|Rickettsiales	L	COG0084 Mg-dependent DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158357_k127_391709_0	336407.RBE_0887	1.239e-113	374.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,47F65@766|Rickettsiales	766|Rickettsiales	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158357_k127_391709_2	293613.A1E_03340	4.681e-44	166.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,47FQG@766|Rickettsiales	766|Rickettsiales	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158357_k127_391709_3	1122164.JHWF01000006_gene274	4.857e-35	136.0	COG0346@1|root,COG0346@2|Bacteria,1N6M5@1224|Proteobacteria,1SUW4@1236|Gammaproteobacteria,1JEWF@118969|Legionellales	118969|Legionellales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158357_k127_391709_1	315456.RF_0210	1.649e-75	258.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,47FA2@766|Rickettsiales	766|Rickettsiales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158357_k127_412504_52	1238182.C882_2618	2.945e-08	55.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2JPS6@204441|Rhodospirillales	204441|Rhodospirillales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158357_k127_412504_0	293613.A1E_00280	1.208e-290	899.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,47EU8@766|Rickettsiales	766|Rickettsiales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	abcT1	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
SRR25158357_k127_412504_36	1121897.AUGO01000011_gene3134	4.314e-31	128.0	COG0655@1|root,COG0655@2|Bacteria,4NP2D@976|Bacteroidetes,1I2A5@117743|Flavobacteriia,2NVET@237|Flavobacterium	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158357_k127_412504_35	357244.OTBS_1076	2.141e-31	128.0	2DNWN@1|root,32ZJJ@2|Bacteria,1NIDI@1224|Proteobacteria,2UMZE@28211|Alphaproteobacteria,47FSP@766|Rickettsiales	766|Rickettsiales	S	Conjugal transfer protein TraD	-	-	-	-	-	-	-	-	-	-	-	-	TraD
SRR25158357_k127_412504_49	357244.OTBS_0925	1.942e-10	63.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2VDAN@28211|Alphaproteobacteria,47FTE@766|Rickettsiales	766|Rickettsiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158357_k127_412504_17	1105110.MC5_06850	1.711e-85	289.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,47FAX@766|Rickettsiales	766|Rickettsiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR25158357_k127_412504_9	452659.RrIowa_0284	3.547e-140	463.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria,47EX8@766|Rickettsiales	766|Rickettsiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158357_k127_412504_33	856793.MICA_697	2.393e-34	141.0	COG3471@1|root,COG3471@2|Bacteria,1R3M5@1224|Proteobacteria,2U044@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
SRR25158357_k127_412504_4	315456.RF_0665	1.009e-185	586.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,47EYN@766|Rickettsiales	766|Rickettsiales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158357_k127_412504_6	391896.A1I_01110	3.801e-157	499.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,47EV4@766|Rickettsiales	766|Rickettsiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158357_k127_412504_41	452659.RrIowa_0893	2.215e-22	104.0	291WZ@1|root,2ZPGK@2|Bacteria,1P6CD@1224|Proteobacteria,2UYCM@28211|Alphaproteobacteria,47FUJ@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_10	315456.RF_0970	3.771e-130	443.0	COG0591@1|root,COG0591@2|Bacteria,1QX2W@1224|Proteobacteria,2TXPA@28211|Alphaproteobacteria,47GTX@766|Rickettsiales	766|Rickettsiales	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158357_k127_412504_29	272947.RP465	1.382e-50	184.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_412504_43	315456.RF_0026	5.033e-21	108.0	COG0457@1|root,COG0457@2|Bacteria	315456.RF_0026|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_53	309807.SRU_1748	7.914e-08	64.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158357_k127_412504_1	1430440.MGMSRv2_0130	1.39e-225	718.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria,2JVAE@204441|Rhodospirillales	204441|Rhodospirillales	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158357_k127_412504_7	1349822.NSB1T_05735	7.272e-148	473.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,2FM8V@200643|Bacteroidia,22W0M@171551|Porphyromonadaceae	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158357_k127_412504_22	944547.ABLL_0822	3.58e-70	246.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,43BJ3@68525|delta/epsilon subdivisions,2YT90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158357_k127_412504_30	1121289.JHVL01000007_gene2805	1.287e-45	181.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,36VW7@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158357_k127_412504_31	1380391.JIAS01000014_gene1964	6.04e-43	174.0	COG1887@1|root,COG1887@2|Bacteria,1NQ9V@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_40	1408312.JNJS01000005_gene677	5.121e-26	123.0	COG0763@1|root,COG0763@2|Bacteria,1UPET@1239|Firmicutes,25HEW@186801|Clostridia,3NHS3@46205|Pseudobutyrivibrio	186801|Clostridia	M	Capsule polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Capsule_synth
SRR25158357_k127_412504_8	1069080.KB913028_gene370	4.958e-146	469.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,4H35J@909932|Negativicutes	909932|Negativicutes	M	UDP-N-acetylglucosamine 4,6-dehydratase	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
SRR25158357_k127_412504_12	1190606.AJYG01000089_gene4531	3.282e-121	399.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1XUNC@135623|Vibrionales	135623|Vibrionales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158357_k127_412504_26	1349767.GJA_932	2.946e-61	222.0	COG0667@1|root,COG0667@2|Bacteria,1RC4U@1224|Proteobacteria,2VMF1@28216|Betaproteobacteria,477DH@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158357_k127_412504_20	443143.GM18_0651	1.231e-71	253.0	COG3980@1|root,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2WIM2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM pseudaminic acid biosynthesis-associated protein PseG	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Glyco_tran_28_C
SRR25158357_k127_412504_38	720555.BATR1942_16235	3.161e-28	120.0	COG1670@1|root,COG1670@2|Bacteria,1V7UX@1239|Firmicutes,4HJPE@91061|Bacilli,1ZIJ1@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
SRR25158357_k127_412504_15	177437.HRM2_36740	2.113e-90	311.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2WJXH@28221|Deltaproteobacteria,2MHVI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM SAF domain	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR25158357_k127_412504_42	1123326.JFBL01000009_gene837	6.048e-22	103.0	COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,42W0U@68525|delta/epsilon subdivisions	1224|Proteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158357_k127_412504_48	207954.MED92_10604	7.37e-11	66.0	COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,1RMXB@1236|Gammaproteobacteria,1XHU0@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158357_k127_412504_13	293614.A1C_02270	9.115e-117	382.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,47F1S@766|Rickettsiales	766|Rickettsiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
SRR25158357_k127_412504_27	315456.RF_1360	4.367e-61	214.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,47FBI@766|Rickettsiales	766|Rickettsiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158357_k127_412504_24	452659.RrIowa_1556	2.41e-63	224.0	COG0170@1|root,COG0170@2|Bacteria,1NAJ2@1224|Proteobacteria,2UJ95@28211|Alphaproteobacteria,47FKJ@766|Rickettsiales	766|Rickettsiales	I	COG0170 Dolichol kinase	sec59	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_3	315456.RF_1358	1.134e-194	623.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,47ETE@766|Rickettsiales	766|Rickettsiales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158357_k127_412504_2	384765.SIAM614_20296	1.553e-199	640.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158357_k127_412504_16	336407.RBE_0060	3.524e-90	302.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria,47F52@766|Rickettsiales	766|Rickettsiales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158357_k127_412504_23	293613.A1E_05430	5.426e-65	231.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,47FB8@766|Rickettsiales	766|Rickettsiales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31,Methyltransf_4
SRR25158357_k127_412504_47	411462.DORLON_02988	1.004e-11	67.0	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_37	1150469.RSPPHO_03257	1.886e-30	123.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,2UJNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_55	1205681.CALW02000074_gene1908	1.756e-05	47.0	2AEC3@1|root,3146K@2|Bacteria,1PTMR@1224|Proteobacteria,2V5H0@28211|Alphaproteobacteria,48UM1@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_44	1123248.KB893324_gene1774	1.002e-18	86.0	2BXJK@1|root,33AIX@2|Bacteria,4NY49@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_56	244582.JQAK01000004_gene111	0.0002223	43.0	2DI3S@1|root,301Y3@2|Bacteria,1PU5T@1224|Proteobacteria,2V5XM@28211|Alphaproteobacteria,47GES@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_39	1150469.RSPPHO_03259	3.201e-28	121.0	2DTV2@1|root,33MS7@2|Bacteria,1NKAB@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_50	500640.CIT292_08961	1.991e-10	64.0	2DS6B@1|root,33ERK@2|Bacteria,1R3PB@1224|Proteobacteria,1STQX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_51	1150469.RSPPHO_03262	6.523e-10	62.0	2D0VD@1|root,32T9B@2|Bacteria,1N8N8@1224|Proteobacteria,2UT48@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_19	257363.RT0201	1.617e-75	254.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,47G6G@766|Rickettsiales	766|Rickettsiales	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_412504_46	86106.I862_04410	2.378e-12	78.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	pipB	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Pentapeptide
SRR25158357_k127_412504_54	1408303.JNJJ01000001_gene3581	1.315e-07	59.0	COG1714@1|root,COG1714@2|Bacteria,1VIH4@1239|Firmicutes,4HSGI@91061|Bacilli,1ZF2E@1386|Bacillus	91061|Bacilli	S	membrane protein domain	yxaI	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158357_k127_412504_14	391896.A1I_06940	4.949e-95	319.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,47FC6@766|Rickettsiales	766|Rickettsiales	M	COG1560 Lauroyl myristoyl acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158357_k127_412504_18	391896.A1I_06945	7.948e-79	274.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2TTZ4@28211|Alphaproteobacteria,47F5U@766|Rickettsiales	766|Rickettsiales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158357_k127_412504_11	293613.A1E_00425	4.765e-126	415.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,47EVA@766|Rickettsiales	766|Rickettsiales	M	Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide- 1,4'-bisphosphate precursor of lipid A	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158357_k127_412504_28	391896.A1I_00875	3.323e-56	203.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,47FIR@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR25158357_k127_412504_5	391896.A1I_00880	7.442e-170	541.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,47EVG@766|Rickettsiales	766|Rickettsiales	E	Aminotransferase	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158357_k127_412504_25	336407.RBE_1332	1.902e-62	227.0	COG0500@1|root,COG0500@2|Bacteria,1N71N@1224|Proteobacteria,2UHXY@28211|Alphaproteobacteria,47GTT@766|Rickettsiales	766|Rickettsiales	Q	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158357_k127_412504_21	272951.rsib_orf591	2.598e-71	250.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria,47FDR@766|Rickettsiales	766|Rickettsiales	M	COG2853 Surface lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
SRR25158357_k127_412504_32	1105110.MC5_00860	9.679e-35	141.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2UAPV@28211|Alphaproteobacteria,47FUB@766|Rickettsiales	766|Rickettsiales	Q	COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR25158357_k127_432763_0	391896.A1I_07480	7.389e-208	654.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,47F0Y@766|Rickettsiales	766|Rickettsiales	C	Dehydrogenase	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158357_k127_432763_3	1110502.TMO_1715	1.231e-127	420.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,2JPJK@204441|Rhodospirillales	204441|Rhodospirillales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158357_k127_432763_1	315456.RF_1019	1.093e-158	505.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,47F43@766|Rickettsiales	766|Rickettsiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158357_k127_432763_2	315456.RF_1020	6.625e-153	488.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,47EV5@766|Rickettsiales	766|Rickettsiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158357_k127_432763_10	1122137.AQXF01000012_gene3453	2.716e-12	66.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,2UG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_432763_4	1150469.RSPPHO_03247	4.59e-41	153.0	2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,2UD5X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_432763_11	1122619.KB892364_gene1143	1.409e-11	64.0	2EK6X@1|root,33DXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_432763_9	1134413.ANNK01000177_gene2478	1.975e-12	67.0	2EG3W@1|root,339VW@2|Bacteria,1TYC4@1239|Firmicutes,4IMIB@91061|Bacilli,1ZK7W@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_432763_5	1382230.ASAP_2763	2.218e-31	124.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_432763_13	928210.CALU01000057_gene337	5.574e-09	58.0	2DTS4@1|root,33MFD@2|Bacteria,1PTGB@1224|Proteobacteria,2V5BU@28211|Alphaproteobacteria,48UEV@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_432763_6	336407.RBE_0887	1.335e-26	116.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,47F65@766|Rickettsiales	766|Rickettsiales	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158357_k127_446546_4	1207063.P24_14055	2.043e-08	58.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JPBG@204441|Rhodospirillales	204441|Rhodospirillales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7
SRR25158357_k127_446546_1	357244.OTBS_2171	1.419e-105	353.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria,47ETR@766|Rickettsiales	766|Rickettsiales	D	Belongs to the SEDS family. MrdB RodA subfamily	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158357_k127_446546_0	391896.A1I_01180	5.458e-220	696.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,47EYD@766|Rickettsiales	766|Rickettsiales	M	Cell division protein FtsI penicillin-binding protein 2	pbpA1	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158357_k127_446546_3	315456.RF_0725	4.892e-53	211.0	COG5183@1|root,COG5183@2|Bacteria,1PUAK@1224|Proteobacteria,2V61C@28211|Alphaproteobacteria,47GHD@766|Rickettsiales	766|Rickettsiales	A	120 KDa Rickettsia surface antigen	sca4	-	-	-	-	-	-	-	-	-	-	-	120_Rick_ant
SRR25158357_k127_446546_5	359.CN09_17120	0.0005948	42.0	COG2801@1|root,COG2801@2|Bacteria,1NAXT@1224|Proteobacteria,2UVUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_446546_2	5722.XP_001580790.1	2.289e-58	220.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
SRR25158357_k127_466051_1	1282876.BAOK01000001_gene1134	7.613e-116	382.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,4BPVZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	flbD	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158357_k127_466051_5	315456.RF_0811	1.818e-68	241.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,47FCB@766|Rickettsiales	766|Rickettsiales	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158357_k127_466051_3	1121948.AUAC01000002_gene1943	1.629e-88	302.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43WDM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	ABC transporter, ATP-binding protein	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158357_k127_466051_6	100901.wOo_06820	3.406e-40	152.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,47FGK@766|Rickettsiales	766|Rickettsiales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxC2	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRR25158357_k127_466051_2	452659.RrIowa_1356	1.318e-96	319.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria,47F6C@766|Rickettsiales	766|Rickettsiales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158357_k127_466051_4	336407.RBE_1307	4.19e-69	240.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2TTWP@28211|Alphaproteobacteria,47FHM@766|Rickettsiales	766|Rickettsiales	S	hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158357_k127_466051_0	293614.A1C_05770	2.858e-192	607.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,47F0T@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158357_k127_466051_7	391600.ABRU01000039_gene2006	2.262e-08	55.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,2KG9K@204458|Caulobacterales	204458|Caulobacterales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158357_k127_475337_0	1144888.CM001467_gene73	7.561e-145	469.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2TT62@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Fatty acid desaturase	aco1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158357_k127_475337_1	7668.SPU_020455-tr	1.508e-22	114.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
SRR25158357_k127_481790_1	1110502.TMO_3004	1.064e-179	574.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2JQ3A@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158357_k127_481790_3	1144888.CM001467_gene898	1.61e-53	197.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,47FNX@766|Rickettsiales	766|Rickettsiales	Q	Methyltransferase domain	bioC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158357_k127_481790_2	293613.A1E_02505	1.092e-53	197.0	COG0741@1|root,COG0741@2|Bacteria,1RDXX@1224|Proteobacteria,2UCH1@28211|Alphaproteobacteria,47FHX@766|Rickettsiales	766|Rickettsiales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltE2	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158357_k127_481790_4	1094557.ME3_01142	5.069e-06	52.0	COG1872@1|root,COG1872@2|Bacteria,1N6V2@1224|Proteobacteria,2UF67@28211|Alphaproteobacteria,48U7B@772|Bartonellaceae	28211|Alphaproteobacteria	S	DUF167	MA20_25230	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158357_k127_481790_0	272951.rsib_orf793	9.39e-295	914.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2TQRS@28211|Alphaproteobacteria,47EVC@766|Rickettsiales	766|Rickettsiales	F	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
SRR25158357_k127_483006_1	163164.WD_0316	1.709e-85	290.0	COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,2V3J4@28211|Alphaproteobacteria,47G3E@766|Rickettsiales	766|Rickettsiales	C	Na+/H+ antiporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
SRR25158357_k127_483006_6	1122135.KB893169_gene2603	6.608e-05	51.0	2E5SK@1|root,330GZ@2|Bacteria	2|Bacteria	N	flagellar assembly	fliX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	FliX
SRR25158357_k127_483006_0	336407.RBE_1147	2.059e-198	627.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,47EXA@766|Rickettsiales	766|Rickettsiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158357_k127_483006_4	452659.RrIowa_1042	1.797e-23	100.0	2EV1K@1|root,33NGP@2|Bacteria,1NQ8R@1224|Proteobacteria,2UKZ4@28211|Alphaproteobacteria,47FTC@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_483006_5	357244.OTBS_0199	2.599e-10	63.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2UF4N@28211|Alphaproteobacteria,47FUQ@766|Rickettsiales	766|Rickettsiales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158357_k127_483006_2	357244.OTBS_1503	2.89e-57	209.0	COG0591@1|root,COG2204@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TY72@28211|Alphaproteobacteria,47GU5@766|Rickettsiales	766|Rickettsiales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
SRR25158357_k127_483006_3	452471.Aasi_0694	2.257e-42	171.0	COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	HD_4,SSF
SRR25158357_k127_492074_5	1116472.MGMO_223c00070	2.878e-21	94.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1XFPG@135618|Methylococcales	135618|Methylococcales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158357_k127_492074_0	315456.RF_0912	2.133e-218	693.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,47F1D@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158357_k127_492074_1	244582.JQAK01000004_gene123	1.641e-149	485.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,2U6FF@28211|Alphaproteobacteria,47FIT@766|Rickettsiales	766|Rickettsiales	G	Sugar phosphate permease	uhpC	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
SRR25158357_k127_492074_3	1122164.JHWF01000008_gene1259	8.422e-31	131.0	2DXIV@1|root,3457A@2|Bacteria,1PSMB@1224|Proteobacteria,1T7A6@1236|Gammaproteobacteria,1JF41@118969|Legionellales	118969|Legionellales	S	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158357_k127_492074_4	870187.Thini_2305	1.977e-28	117.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,1RW2B@1236|Gammaproteobacteria,4635U@72273|Thiotrichales	72273|Thiotrichales	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158357_k127_492074_2	347834.RHE_CH02953	4.076e-41	155.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,4B9WA@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR25158357_k127_517014_5	315456.RF_0983	1.45e-08	61.0	2ACQT@1|root,312BE@2|Bacteria,1PQGZ@1224|Proteobacteria,2V2VZ@28211|Alphaproteobacteria,47GN9@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF2660)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2660
SRR25158357_k127_517014_2	257363.RT0482	6.844e-60	215.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TTPD@28211|Alphaproteobacteria,47FFS@766|Rickettsiales	766|Rickettsiales	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158357_k127_517014_1	336407.RBE_0680	5.587e-62	222.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,47FB4@766|Rickettsiales	766|Rickettsiales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158357_k127_517014_0	315456.RF_1318	4.164e-94	314.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,47F8T@766|Rickettsiales	766|Rickettsiales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158357_k127_517014_3	293614.A1C_06430	1.222e-46	169.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,47FHH@766|Rickettsiales	766|Rickettsiales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SRR25158357_k127_517014_4	1211817.CCAT010000091_gene2178	2.131e-41	157.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	agcS_1	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
SRR25158357_k127_540850_7	257363.RT0101	2.303e-11	70.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,1MX2X@1224|Proteobacteria,2TSMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
SRR25158357_k127_540850_2	293614.A1C_04580	1.062e-76	260.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2TQZM@28211|Alphaproteobacteria,47FDN@766|Rickettsiales	766|Rickettsiales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158357_k127_540850_0	391896.A1I_04570	5.183e-176	565.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,47F0Q@766|Rickettsiales	766|Rickettsiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158357_k127_540850_6	391896.A1I_07660	2.078e-21	95.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,47FT5@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158357_k127_540850_5	391896.A1I_07655	7.616e-40	150.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,47FHR@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158357_k127_540850_3	336407.RBE_0689	4.953e-76	263.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,2TU31@28211|Alphaproteobacteria,47F35@766|Rickettsiales	766|Rickettsiales	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
SRR25158357_k127_540850_4	1144888.CM001467_gene296	1.226e-50	184.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,47FHU@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
SRR25158357_k127_540850_1	1105110.MC5_01565	2.192e-99	330.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,47EWQ@766|Rickettsiales	766|Rickettsiales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158357_k127_552369_7	203119.Cthe_3049	1.521e-23	108.0	COG0457@1|root,COG0457@2|Bacteria,1TTRQ@1239|Firmicutes,24WEN@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158357_k127_552369_11	8153.XP_005953363.1	0.0002811	52.0	28M36@1|root,2QTJW@2759|Eukaryota,39Z88@33154|Opisthokonta,3BMRG@33208|Metazoa,3D58C@33213|Bilateria	33208|Metazoa	S	NACHT domain	-	-	-	ko:K12800	ko04217,ko04621,ko05133,ko05164,map04217,map04621,map05133,map05164	-	-	-	ko00000,ko00001,ko04131	-	-	-	FISNA,LRR_6,NACHT
SRR25158357_k127_552369_10	675814.VIC_005078	5.834e-17	96.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	DUF637,Fil_haemagg_2,Haemagg_act
SRR25158357_k127_552369_9	1430440.MGMSRv2_2298	1.982e-21	95.0	COG2161@1|root,COG2161@2|Bacteria,1NBSZ@1224|Proteobacteria,2UMG9@28211|Alphaproteobacteria,2JZRS@204441|Rhodospirillales	204441|Rhodospirillales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158357_k127_552369_8	1485545.JQLW01000007_gene758	2.867e-23	102.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria	1224|Proteobacteria	D	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	2.3.1.30	ko:K00640,ko:K07062	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000,ko02048	-	-	-	PIN
SRR25158357_k127_552369_0	315456.RF_1262	3.552e-281	878.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,47F11@766|Rickettsiales	766|Rickettsiales	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
SRR25158357_k127_552369_2	272951.rsib_orf874	3.629e-172	545.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,47EYG@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158357_k127_552369_4	315456.RF_1260	4.95e-86	286.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,47F77@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3,1.6.99.3	ko:K00338,ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Fer4
SRR25158357_k127_552369_5	272951.rsib_orf880	1.957e-58	209.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,47FDH@766|Rickettsiales	766|Rickettsiales	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158357_k127_552369_6	1105110.MC5_01725	1.931e-38	145.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,47FFJ@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158357_k127_552369_1	336407.RBE_0087	1.609e-244	770.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,47EU1@766|Rickettsiales	766|Rickettsiales	C	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
SRR25158357_k127_552369_3	391896.A1I_07505	2.558e-87	293.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,47EU0@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158357_k127_562014_3	336407.RBE_0807	4.473e-43	161.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,47FMU@766|Rickettsiales	766|Rickettsiales	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158357_k127_562014_1	336407.RBE_0808	1.606e-165	535.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2TVJN@28211|Alphaproteobacteria,47FAQ@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF1705)	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
SRR25158357_k127_562014_2	293614.A1C_02380	4.861e-112	373.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria,47F26@766|Rickettsiales	766|Rickettsiales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158357_k127_562014_0	391896.A1I_07050	3.002e-168	550.0	COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,47F86@766|Rickettsiales	766|Rickettsiales	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
SRR25158357_k127_562014_5	27923.ML071158a-PA	5.289e-08	55.0	KOG3245@1|root,KOG3245@2759|Eukaryota,3A8BP@33154|Opisthokonta,3BUKS@33208|Metazoa	33208|Metazoa	S	Succinate dehydrogenase complex assembly factor 4	C6orf57	GO:0000104,GO:0000302,GO:0001654,GO:0002376,GO:0003407,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005749,GO:0006091,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0006996,GO:0007005,GO:0007275,GO:0007423,GO:0008150,GO:0008152,GO:0008177,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0033108,GO:0033554,GO:0034552,GO:0034553,GO:0034599,GO:0034614,GO:0034622,GO:0042221,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045087,GO:0045257,GO:0045273,GO:0045281,GO:0045283,GO:0045333,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051716,GO:0055114,GO:0060041,GO:0065003,GO:0070469,GO:0070887,GO:0071840,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901700,GO:1901701,GO:1902494,GO:1990204	-	-	-	-	-	-	-	-	-	-	DUF1674
SRR25158357_k127_562014_4	336407.RBE_1141	4.816e-08	58.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,47FII@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158357_k127_614715_4	1144888.CM001467_gene360	1.115e-16	84.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,47F0M@766|Rickettsiales	766|Rickettsiales	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
SRR25158357_k127_614715_2	1144888.CM001467_gene2	1.298e-51	190.0	COG1738@1|root,COG1738@2|Bacteria,1PWED@1224|Proteobacteria,2U8W0@28211|Alphaproteobacteria,47F8C@766|Rickettsiales	766|Rickettsiales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158357_k127_614715_3	272951.rsib_orf229	3.206e-41	157.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,47FN4@766|Rickettsiales	766|Rickettsiales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158357_k127_614715_0	334545.CCMG01000018_gene1416	1.006e-149	505.0	COG2982@1|root,COG2982@2|Bacteria,1MZ30@1224|Proteobacteria,2UBUY@28211|Alphaproteobacteria,47FIV@766|Rickettsiales	766|Rickettsiales	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
SRR25158357_k127_614715_1	452659.RrIowa_0640	5.322e-117	395.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2TWGV@28211|Alphaproteobacteria,47GTJ@766|Rickettsiales	766|Rickettsiales	G	COG0477 Permeases of the major facilitator superfamily	ampG4	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR25158357_k127_625144_13	391896.A1I_03855	1.076e-68	241.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,47FI0@766|Rickettsiales	766|Rickettsiales	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158357_k127_625144_8	315456.RF_1035	4.275e-111	368.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,47EXR@766|Rickettsiales	766|Rickettsiales	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158357_k127_625144_6	334545.CCMG01000015_gene1255	1.45e-122	399.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,47EXB@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158357_k127_625144_2	336407.RBE_0963	1.115e-206	652.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,47EYW@766|Rickettsiales	766|Rickettsiales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M,Zn_ribbon_recom
SRR25158357_k127_625144_20	334545.CCMG01000008_gene397	2.993e-31	127.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,47FMZ@766|Rickettsiales	766|Rickettsiales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158357_k127_625144_16	357244.OTBS_0999	5.031e-54	211.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	AAA_23,BPD_transp_2,DUF3732
SRR25158357_k127_625144_26	985054.JQEZ01000003_gene1678	0.000108	48.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,2U5P8@28211|Alphaproteobacteria,4NADK@97050|Ruegeria	28211|Alphaproteobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158357_k127_625144_18	118173.KB235914_gene2162	3.548e-36	140.0	COG1443@1|root,COG1443@2|Bacteria,1GDFS@1117|Cyanobacteria	1117|Cyanobacteria	I	NUDIX domain	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158357_k127_625144_3	1123355.JHYO01000005_gene935	4.296e-178	565.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,36X39@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	aatC	GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158357_k127_625144_4	1144888.CM001467_gene1119	1.015e-160	512.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,47EZC@766|Rickettsiales	766|Rickettsiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158357_k127_625144_14	334545.CCMG01000018_gene1468	1.076e-59	212.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,47FG4@766|Rickettsiales	766|Rickettsiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158357_k127_625144_9	257363.RT0363	3.816e-97	332.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47G8R@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP3	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158357_k127_625144_21	391896.A1I_07475	2.386e-27	118.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,47FRS@766|Rickettsiales	766|Rickettsiales	F	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158357_k127_625144_1	315456.RF_1268	3.353e-243	759.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,47F0F@766|Rickettsiales	766|Rickettsiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158357_k127_625144_10	1105110.MC5_01655	1.597e-88	300.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,47F6G@766|Rickettsiales	766|Rickettsiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158357_k127_625144_24	856793.MICA_1922	3.26e-14	74.0	COG1942@1|root,COG1942@2|Bacteria	2|Bacteria	S	isomerase activity	dmpI	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158357_k127_625144_0	336407.RBE_0096	7.843e-256	794.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,47ETU@766|Rickettsiales	766|Rickettsiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158357_k127_625144_25	1325130.HFN_2396	4.318e-10	65.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SRR25158357_k127_625144_15	391896.A1I_01840	1.01e-57	203.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2UJ9N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158357_k127_625144_22	1144888.CM001467_gene1472	2.882e-22	99.0	COG1324@1|root,COG1324@2|Bacteria,1Q75M@1224|Proteobacteria,2VDA1@28211|Alphaproteobacteria,47FRU@766|Rickettsiales	766|Rickettsiales	P	protein involved in tolerance to divalent cations	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158357_k127_625144_5	336407.RBE_1095	4.052e-159	511.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,47F41@766|Rickettsiales	766|Rickettsiales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158357_k127_625144_12	1105110.MC5_06685	1.079e-69	245.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,47FIM@766|Rickettsiales	766|Rickettsiales	S	transport system periplasmic component	imp	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158357_k127_625144_17	391896.A1I_02970	1.852e-49	180.0	COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,2UABJ@28211|Alphaproteobacteria,47GEC@766|Rickettsiales	766|Rickettsiales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158357_k127_625144_23	643562.Daes_3209	1.895e-21	100.0	29XY6@1|root,30JQT@2|Bacteria,1PWGF@1224|Proteobacteria,4373T@68525|delta/epsilon subdivisions,2X1XZ@28221|Deltaproteobacteria,2MFU4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Lipid A 3-O-deacylase (PagL)	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PagL
SRR25158357_k127_625144_11	334545.CCMG01000014_gene1129	2.897e-86	290.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,47F9V@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
SRR25158357_k127_625144_19	391896.A1I_01720	4.722e-34	136.0	COG0781@1|root,COG0781@2|Bacteria,1PRNA@1224|Proteobacteria,2VAAJ@28211|Alphaproteobacteria,47FSA@766|Rickettsiales	766|Rickettsiales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158357_k127_625144_7	315456.RF_1121	7.044e-113	374.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,47EU7@766|Rickettsiales	766|Rickettsiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158357_k127_625481_1	1144888.CM001467_gene1395	2.742e-268	832.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,47EWK@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158357_k127_625481_2	334545.CCMG01000002_gene136	1.396e-142	464.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,47F0S@766|Rickettsiales	766|Rickettsiales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
SRR25158357_k127_625481_4	1528098.NOVO_02360	6.793e-16	83.0	COG3838@1|root,COG3838@2|Bacteria,1NHHS@1224|Proteobacteria,2UK92@28211|Alphaproteobacteria,47FSB@766|Rickettsiales	766|Rickettsiales	U	TrbC/VIRB2 family	-	-	-	-	-	-	-	-	-	-	-	-	TrbC
SRR25158357_k127_625481_3	336407.RBE_0705	1.284e-73	261.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,2TRSC@28211|Alphaproteobacteria,47FA6@766|Rickettsiales	766|Rickettsiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158357_k127_625481_0	315456.RF_1109	0.0	1163.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,47EX4@766|Rickettsiales	766|Rickettsiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18989	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00720	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.30	-	-	ACR_tran
SRR25158357_k127_667864_3	700598.Niako_1237	1.005e-34	139.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG2823 periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158357_k127_667864_1	272947.RP147	8.37e-72	250.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,47F5J@766|Rickettsiales	766|Rickettsiales	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
SRR25158357_k127_667864_0	315456.RF_0417	0.0	1392.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,47EUX@766|Rickettsiales	766|Rickettsiales	I	COG0477 Permeases of the major facilitator superfamily	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
SRR25158357_k127_667864_4	1269813.ATUL01000002_gene940	3.074e-07	56.0	COG2823@1|root,COG2823@2|Bacteria,1MY8V@1224|Proteobacteria,1S2D4@1236|Gammaproteobacteria,1X04P@135613|Chromatiales	135613|Chromatiales	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158357_k127_667864_2	1385420.FRA_27c02730	8.28e-71	254.0	COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,1RNBM@1236|Gammaproteobacteria,460FN@72273|Thiotrichales	72273|Thiotrichales	M	mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
SRR25158357_k127_702860_10	1144888.CM001467_gene728	3.396e-13	74.0	COG5462@1|root,COG5462@2|Bacteria	2|Bacteria	-	-	MA20_01770	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_702860_2	334545.CCMG01000007_gene343	3.171e-110	364.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,47F76@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158357_k127_702860_4	293614.A1C_04410	2.734e-57	203.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,47FG2@766|Rickettsiales	766|Rickettsiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158357_k127_702860_1	452659.RrIowa_0541	1.76e-140	452.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,47F2C@766|Rickettsiales	766|Rickettsiales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	hflC1	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
SRR25158357_k127_702860_13	227086.JGI_V11_31340	7.509e-10	70.0	COG0666@1|root,KOG0508@2759|Eukaryota	2759|Eukaryota	L	EP4 subtype prostaglandin E2 receptor binding	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
SRR25158357_k127_702860_8	357244.OTBS_0156	2.905e-15	77.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158357_k127_702860_5	336407.RBE_0453	1.489e-43	166.0	COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria,47FK8@766|Rickettsiales	766|Rickettsiales	S	COQ9	-	-	-	ko:K18587	-	-	-	-	ko00000	-	-	-	COQ9
SRR25158357_k127_702860_0	315456.RF_0423	0.0	1585.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,47EW6@766|Rickettsiales	766|Rickettsiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158357_k127_702860_7	300852.55772814	6.745e-25	109.0	COG5502@1|root,COG5502@2|Bacteria,1WJW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158357_k127_702860_6	86106.I862_03000	3.259e-26	111.0	COG1873@1|root,COG1873@2|Bacteria,1Q8QQ@1224|Proteobacteria,2UXPP@28211|Alphaproteobacteria,47GM4@766|Rickettsiales	766|Rickettsiales	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_702860_15	985867.AEWF01000010_gene1201	0.0005777	48.0	2DHSP@1|root,300SY@2|Bacteria,1Q6FN@1224|Proteobacteria,2VCKR@28211|Alphaproteobacteria,47GDN@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_702860_12	272947.RP169	1.717e-11	67.0	COG2155@1|root,COG2155@2|Bacteria,1PUGT@1224|Proteobacteria,2V65G@28211|Alphaproteobacteria,47GK4@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
SRR25158357_k127_702860_9	195250.CM001776_gene4	1.013e-13	85.0	COG1357@1|root,COG1357@2|Bacteria,1G6CI@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158357_k127_702860_14	1211813.CAPH01000006_gene1405	0.0002971	53.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,2FPSW@200643|Bacteroidia	976|Bacteroidetes	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158357_k127_702860_11	293613.A1E_01230	2.818e-12	69.0	292EY@1|root,2ZPZ7@2|Bacteria,1P851@1224|Proteobacteria,2UYGP@28211|Alphaproteobacteria,47GNZ@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF2671)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2671
SRR25158357_k127_702860_3	257363.RT0205	8.09e-86	295.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47ET5@766|Rickettsiales	766|Rickettsiales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	abcT3	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158357_k127_714802_5	1528098.NOVO_07650	2.067e-45	171.0	COG1502@1|root,COG1502@2|Bacteria,1N31R@1224|Proteobacteria,2UBQT@28211|Alphaproteobacteria,47FHI@766|Rickettsiales	766|Rickettsiales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	pld	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158357_k127_714802_4	293614.A1C_04890	5.078e-71	248.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,47F68@766|Rickettsiales	766|Rickettsiales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,Methyltransf_11,Methyltransf_23
SRR25158357_k127_714802_2	315456.RF_1200	1.604e-103	349.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,47F22@766|Rickettsiales	766|Rickettsiales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
SRR25158357_k127_714802_6	1101191.KI912577_gene3204	2.706e-26	117.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,2TREM@28211|Alphaproteobacteria,1JSA7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRR25158357_k127_714802_3	1441629.PCH70_30440	2.128e-81	286.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,1RPPF@1236|Gammaproteobacteria,1Z6UX@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRR25158357_k127_714802_9	1283299.AUKG01000002_gene4461	1.449e-05	54.0	COG2156@1|root,COG2156@2|Bacteria,2GK75@201174|Actinobacteria,4CSDB@84995|Rubrobacteria	84995|Rubrobacteria	P	K+-transporting ATPase, c chain	-	-	-	-	-	-	-	-	-	-	-	-	KdpC
SRR25158357_k127_714802_1	1123366.TH3_04789	1.148e-124	406.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2JRG4@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158357_k127_714802_0	334545.CCMG01000002_gene107	3.424e-194	608.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,47ETF@766|Rickettsiales	766|Rickettsiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRR25158357_k127_714802_7	293613.A1E_02970	8.206e-13	70.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,47EWS@766|Rickettsiales	766|Rickettsiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158357_k127_732484_4	272951.rsib_orf1220	1.959e-66	234.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,47GHE@766|Rickettsiales	766|Rickettsiales	M	COG0760 Parvulin-like peptidyl-prolyl isomerase	prsA	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
SRR25158357_k127_732484_0	336407.RBE_0897	0.0	1262.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,47EYC@766|Rickettsiales	766|Rickettsiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158357_k127_732484_3	391896.A1I_02420	2.609e-70	245.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,47F62@766|Rickettsiales	766|Rickettsiales	S	glutamine amidotransferases	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158357_k127_732484_1	272951.rsib_orf1302	1.702e-152	487.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,47EXD@766|Rickettsiales	766|Rickettsiales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158357_k127_732484_2	336407.RBE_0699	1.245e-74	256.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,47FK3@766|Rickettsiales	766|Rickettsiales	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158357_k127_739860_1	869213.JCM21142_31199	3.755e-68	239.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158357_k127_739860_0	315456.RF_0233	4.945e-107	362.0	COG0477@1|root,COG0477@2|Bacteria,1RG0P@1224|Proteobacteria,2U7W3@28211|Alphaproteobacteria,47F8M@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP4	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158357_k127_7453_1	1105110.MC5_05420	4.401e-145	462.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,47ET3@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158357_k127_7453_4	1144888.CM001467_gene1177	1.77e-71	246.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,47FCH@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158357_k127_7453_2	1144888.CM001467_gene1176	1.241e-95	314.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,47EZV@766|Rickettsiales	766|Rickettsiales	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3,1.6.99.3	ko:K00331,ko:K03940	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Oxidored_q6
SRR25158357_k127_7453_5	391896.A1I_05770	2.735e-53	189.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,47FH2@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158357_k127_7453_7	1122962.AULH01000007_gene1927	1.139e-10	69.0	COG1815@1|root,COG1815@2|Bacteria,1N1G1@1224|Proteobacteria,2UCJ4@28211|Alphaproteobacteria,36YXR@31993|Methylocystaceae	28211|Alphaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
SRR25158357_k127_7453_6	86106.I862_04950	9.778e-35	138.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2U94I@28211|Alphaproteobacteria,47FQE@766|Rickettsiales	766|Rickettsiales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
SRR25158357_k127_7453_8	1122180.Lokhon_00193	0.000776	48.0	COG1677@1|root,COG1677@2|Bacteria,1PRFY@1224|Proteobacteria,2V3R8@28211|Alphaproteobacteria,2P9Y0@245186|Loktanella	28211|Alphaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	-	-	-	-	-	-	-	-	-	FliE
SRR25158357_k127_7453_0	862908.BMS_1669	1.642e-236	748.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,42N6Q@68525|delta/epsilon subdivisions,2WJVG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168	-	-	-	-	ko00000,ko02000	2.A.15.1.3,2.A.15.1.4	-	-	BCCT
SRR25158357_k127_7453_3	336407.RBE_1073	9.27e-76	258.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,47F9H@766|Rickettsiales	766|Rickettsiales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SRR25158357_k127_760372_17	44689.DDB0188488	7.258e-05	52.0	2E4H1@1|root,2SG7J@2759|Eukaryota,3XHA1@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_760372_16	1122929.KB908222_gene2473	2.283e-05	49.0	COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	small protein containing a coiled-coil domain	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
SRR25158357_k127_760372_15	314270.RB2083_588	2.188e-06	61.0	COG1357@1|root,COG1357@2|Bacteria,1RFRV@1224|Proteobacteria,2U7UC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158357_k127_760372_2	1144888.CM001467_gene741	1.923e-202	641.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,47EYI@766|Rickettsiales	766|Rickettsiales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158357_k127_760372_3	293613.A1E_01705	9.064e-195	625.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,47ETC@766|Rickettsiales	766|Rickettsiales	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158357_k127_760372_13	985867.AEWF01000004_gene323	6.473e-19	88.0	COG2204@1|root,COG2204@2|Bacteria,1Q76E@1224|Proteobacteria,2UW7Q@28211|Alphaproteobacteria,47FTT@766|Rickettsiales	766|Rickettsiales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
SRR25158357_k127_760372_4	391896.A1I_01285	1.097e-145	469.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,47ETX@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158357_k127_760372_9	1528098.NOVO_07630	1.377e-86	308.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,47F66@766|Rickettsiales	766|Rickettsiales	CO	Thioredoxin-like	dsbD	-	-	ko:K08344	-	-	-	-	ko00000,ko02000	5.A.1.5	-	-	DsbC,DsbD,Thioredoxin_7
SRR25158357_k127_760372_11	336407.RBE_0027	3.21e-51	188.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria,47FJH@766|Rickettsiales	766|Rickettsiales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158357_k127_760372_7	315456.RF_1238	1.365e-112	370.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,47ETT@766|Rickettsiales	766|Rickettsiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158357_k127_760372_10	1207063.P24_11000	2.696e-51	208.0	COG0457@1|root,COG3266@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,1N09H@1224|Proteobacteria,2TSKT@28211|Alphaproteobacteria,2JR81@204441|Rhodospirillales	204441|Rhodospirillales	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_760372_8	336407.RBE_0171	7.653e-102	350.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,47FMX@766|Rickettsiales	766|Rickettsiales	O	COG0760 Parvulin-like peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
SRR25158357_k127_760372_12	357244.OTBS_0140	3.373e-46	175.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,47FEY@766|Rickettsiales	766|Rickettsiales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158357_k127_760372_14	1528098.NOVO_02280	8.517e-16	81.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,2UJYU@28211|Alphaproteobacteria,47FSY@766|Rickettsiales	766|Rickettsiales	U	Involved in protein export. Participates in an early event of protein translocation (By similarity)	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158357_k127_760372_5	336407.RBE_1345	6.788e-123	399.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,47EY9@766|Rickettsiales	766|Rickettsiales	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158357_k127_760372_0	1122164.JHWF01000014_gene1801	8.082e-223	699.0	COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,1T2WG@1236|Gammaproteobacteria,1JDFU@118969|Legionellales	118969|Legionellales	E	Amino acid permease	-	-	-	ko:K03293	-	-	-	-	ko00000	2.A.3.1	-	-	AA_permease
SRR25158357_k127_760372_1	1105110.MC5_02045	4.319e-216	680.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47G4H@766|Rickettsiales	766|Rickettsiales	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlcE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015931,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
SRR25158357_k127_760372_6	1105110.MC5_00285	3.568e-122	402.0	COG2227@1|root,COG4797@1|root,COG2227@2|Bacteria,COG4797@2|Bacteria,1QU8H@1224|Proteobacteria,2TWMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25,Methyltransf_31
SRR25158357_k127_783500_14	391896.A1I_02625	1.25e-30	124.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,47GQS@766|Rickettsiales	766|Rickettsiales	P	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
SRR25158357_k127_783500_3	86106.I862_02575	2.421e-150	483.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,47F15@766|Rickettsiales	766|Rickettsiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158357_k127_783500_18	293613.A1E_01310	4.09e-11	75.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_4
SRR25158357_k127_783500_24	264203.ZMO1876	2.452e-06	55.0	COG3827@1|root,COG3827@2|Bacteria,1MX61@1224|Proteobacteria,2TSG8@28211|Alphaproteobacteria,2K7EP@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09991	-	-	-	-	ko00000	-	-	-	DUF2497
SRR25158357_k127_783500_4	293613.A1E_01300	6.249e-121	402.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,47FGW@766|Rickettsiales	766|Rickettsiales	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158357_k127_783500_9	391896.A1I_04350	2.931e-73	254.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,47FGU@766|Rickettsiales	766|Rickettsiales	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SRR25158357_k127_783500_6	315456.RF_0699	3.178e-98	329.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,47EXQ@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158357_k127_783500_2	10228.TriadP60547	4.932e-172	549.0	COG0766@1|root,2QV7D@2759|Eukaryota,38E4I@33154|Opisthokonta,3BMMH@33208|Metazoa	33208|Metazoa	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	EPSP_synthase
SRR25158357_k127_783500_0	336407.RBE_0412	3.561e-254	795.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,47EU9@766|Rickettsiales	766|Rickettsiales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158357_k127_783500_12	293613.A1E_02580	3.692e-66	232.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,47FJY@766|Rickettsiales	766|Rickettsiales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158357_k127_783500_23	1197906.CAJQ02000027_gene1525	8.698e-08	55.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158357_k127_783500_21	1040987.AZUY01000046_gene4435	2.424e-09	58.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,Tn7_Tnp_TnsA_N
SRR25158357_k127_783500_16	297246.plpp0071	7.214e-28	121.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,1JF4K@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
SRR25158357_k127_783500_13	658187.LDG_7148	6.134e-46	173.0	COG0454@1|root,COG0456@2|Bacteria,1NCA0@1224|Proteobacteria,1SIB6@1236|Gammaproteobacteria,1JCAA@118969|Legionellales	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158357_k127_783500_15	336407.RBE_0769	2.917e-28	119.0	COG5183@1|root,COG5183@2|Bacteria,1PUAK@1224|Proteobacteria,2V61C@28211|Alphaproteobacteria,47GHD@766|Rickettsiales	766|Rickettsiales	A	120 KDa Rickettsia surface antigen	sca4	-	-	-	-	-	-	-	-	-	-	-	120_Rick_ant
SRR25158357_k127_783500_20	257363.RT0485	5.186e-10	72.0	COG5183@1|root,COG5183@2|Bacteria,1PUAK@1224|Proteobacteria,2V61C@28211|Alphaproteobacteria,47GHD@766|Rickettsiales	766|Rickettsiales	A	120 KDa Rickettsia surface antigen	sca4	-	-	-	-	-	-	-	-	-	-	-	120_Rick_ant
SRR25158357_k127_783500_25	91604.ID47_07430	0.0004132	43.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,47G6C@766|Rickettsiales	766|Rickettsiales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158357_k127_783500_17	658187.LDG_7104	1.394e-21	96.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria,1JGI1@118969|Legionellales	1236|Gammaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158357_k127_783500_22	930169.B5T_04356	2.056e-08	62.0	COG5395@1|root,COG5395@2|Bacteria,1N0CF@1224|Proteobacteria,1SBQ3@1236|Gammaproteobacteria,1XMJ3@135619|Oceanospirillales	135619|Oceanospirillales	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
SRR25158357_k127_783500_8	1399147.P618_200431	2.121e-90	299.0	COG0454@1|root,COG0456@2|Bacteria,1NCA0@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158357_k127_783500_1	1399147.P618_200430	7.008e-178	577.0	COG0454@1|root,COG2320@1|root,COG0456@2|Bacteria,COG2320@2|Bacteria,1R6Y0@1224|Proteobacteria,2VFQ1@28211|Alphaproteobacteria,47GRR@766|Rickettsiales	766|Rickettsiales	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,GrpB
SRR25158357_k127_783500_7	1268635.Loa_02063	9.505e-96	337.0	COG3173@1|root,COG3173@2|Bacteria,1PN9I@1224|Proteobacteria,1RVJZ@1236|Gammaproteobacteria,1JFMX@118969|Legionellales	118969|Legionellales	K	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158357_k127_783500_10	658187.LDG_7101	8.199e-70	238.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Cupin_2
SRR25158357_k127_783500_11	391896.A1I_02805	1.26e-66	230.0	COG3708@1|root,COG3708@2|Bacteria,1RK32@1224|Proteobacteria,2UBD7@28211|Alphaproteobacteria,47F9B@766|Rickettsiales	766|Rickettsiales	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
SRR25158357_k127_783500_5	1385420.FRA_50c14570	6.605e-102	334.0	COG3896@1|root,COG3896@2|Bacteria,1NEN0@1224|Proteobacteria,1STA5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
SRR25158357_k127_785353_1	315456.RF_0068	5.771e-187	594.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,47ETK@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158357_k127_785353_6	658187.LDG_7086	7.613e-21	93.0	COG3173@1|root,COG3173@2|Bacteria,1R5XN@1224|Proteobacteria,1S9H0@1236|Gammaproteobacteria,1JCDI@118969|Legionellales	1236|Gammaproteobacteria	J	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158357_k127_785353_7	1089439.KB902274_gene1868	6.068e-15	75.0	COG3173@1|root,COG3173@2|Bacteria,1R5XN@1224|Proteobacteria,1S9H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158357_k127_785353_4	1528098.NOVO_07195	3.12e-82	283.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158357_k127_785353_5	1399147.P618_200421	3.345e-36	139.0	COG0454@1|root,COG0456@2|Bacteria,1RH0C@1224|Proteobacteria,2U9B4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	phnO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158357_k127_785353_2	1105110.MC5_06840	4.191e-149	481.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,47EVB@766|Rickettsiales	766|Rickettsiales	A	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158357_k127_785353_0	315456.RF_1084	1.831e-283	880.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,47EZM@766|Rickettsiales	766|Rickettsiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158357_k127_798786_4	985867.AEWF01000003_gene992	7.434e-77	265.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,47F06@766|Rickettsiales	766|Rickettsiales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
SRR25158357_k127_798786_6	1123355.JHYO01000001_gene3333	1.681e-40	151.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,36YP2@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158357_k127_798786_0	452659.RrIowa_0005	6.274e-275	877.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1QVTW@1224|Proteobacteria,2TWJK@28211|Alphaproteobacteria,47EUW@766|Rickettsiales	766|Rickettsiales	CEH	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
SRR25158357_k127_798786_1	504472.Slin_0816	2.897e-254	805.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,47KWM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
SRR25158357_k127_798786_2	1123277.KB893206_gene3248	1.548e-119	398.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47M8T@768503|Cytophagia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158357_k127_798786_3	1123277.KB893206_gene3249	6.974e-116	379.0	COG0583@1|root,COG0583@2|Bacteria,4NXN1@976|Bacteroidetes	976|Bacteroidetes	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158357_k127_798786_7	1528098.NOVO_08605	4.37e-36	142.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2U5Q5@28211|Alphaproteobacteria,47FKU@766|Rickettsiales	766|Rickettsiales	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
SRR25158357_k127_798786_5	257363.RT0677	2.979e-66	230.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,47F6Y@766|Rickettsiales	766|Rickettsiales	L	COG0084 Mg-dependent DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158357_k127_861833_1	315456.RF_0709	6.404e-309	955.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,47EWS@766|Rickettsiales	766|Rickettsiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158357_k127_861833_4	391896.A1I_07530	5.985e-54	200.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	OMP_b-brl,PagL
SRR25158357_k127_861833_2	1144888.CM001467_gene328	2.439e-189	604.0	COG2227@1|root,COG4797@1|root,COG2227@2|Bacteria,COG4797@2|Bacteria,1QU8H@1224|Proteobacteria,2TWMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25,Methyltransf_31
SRR25158357_k127_861833_3	336407.RBE_1394	8.473e-104	351.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,47FA1@766|Rickettsiales	766|Rickettsiales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158357_k127_861833_0	336407.RBE_1393	3.76e-311	963.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,47F48@766|Rickettsiales	766|Rickettsiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158357_k127_861833_5	244582.JQAK01000001_gene1541	2.543e-35	141.0	COG0494@1|root,COG0494@2|Bacteria,1NWIQ@1224|Proteobacteria,2US7U@28211|Alphaproteobacteria,47FS7@766|Rickettsiales	766|Rickettsiales	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_874187_1	391896.A1I_03680	0.0	1077.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,47EU2@766|Rickettsiales	766|Rickettsiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158357_k127_874187_3	1144888.CM001467_gene216	4.442e-149	478.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,47F1I@766|Rickettsiales	766|Rickettsiales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR25158357_k127_874187_5	315456.RF_0644	5.666e-97	327.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,2TVC0@28211|Alphaproteobacteria,47F9U@766|Rickettsiales	766|Rickettsiales	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158357_k127_874187_7	315456.RF_0711	1.155e-37	161.0	COG1357@1|root,COG1357@2|Bacteria,1NIY1@1224|Proteobacteria,2UKGI@28211|Alphaproteobacteria,47FS0@766|Rickettsiales	766|Rickettsiales	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158357_k127_874187_8	86106.I862_01665	9.071e-31	141.0	COG1357@1|root,COG1357@2|Bacteria,1NIY1@1224|Proteobacteria,2UKGI@28211|Alphaproteobacteria,47FS0@766|Rickettsiales	766|Rickettsiales	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158357_k127_874187_9	293614.A1C_05645	1.401e-07	57.0	COG3027@1|root,COG3027@2|Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRR25158357_k127_874187_10	1069080.KB913028_gene796	6.137e-07	57.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4H4XS@909932|Negativicutes	909932|Negativicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158357_k127_874187_0	1528098.NOVO_05370	0.0	1142.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,47F1Y@766|Rickettsiales	766|Rickettsiales	E	NAD-specific glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158357_k127_874187_2	1144888.CM001467_gene375	9.337e-155	500.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,47EX9@766|Rickettsiales	766|Rickettsiales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	trmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158357_k127_874187_4	336407.RBE_0177	3.823e-111	367.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,47F59@766|Rickettsiales	766|Rickettsiales	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158357_k127_874187_6	1528098.NOVO_07670	1.508e-57	203.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,47FBY@766|Rickettsiales	766|Rickettsiales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158357_k127_927039_0	336407.RBE_0342	4.701e-123	425.0	COG0591@1|root,COG0642@1|root,COG5002@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_927039_1	272947.RP465	2.942e-33	132.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,47GQ4@766|Rickettsiales	766|Rickettsiales	T	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
SRR25158357_k127_931537_0	391896.A1I_03420	1.85e-274	852.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,47EUT@766|Rickettsiales	766|Rickettsiales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158357_k127_931537_1	336407.RBE_0598	1.575e-154	494.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,47EUM@766|Rickettsiales	766|Rickettsiales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158357_k127_931537_2	391896.A1I_02485	6.674e-100	337.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,47F3Z@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158357_k127_942752_4	1215915.BN193_04295	0.0001863	55.0	COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4I2R6@91061|Bacilli,1YC59@1357|Lactococcus	91061|Bacilli	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158357_k127_942752_2	357244.OTBS_1486	1.281e-126	427.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,47EYR@766|Rickettsiales	766|Rickettsiales	O	Cytochrome c-type biogenesis protein ccmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158357_k127_942752_1	336407.RBE_0197	4.606e-143	465.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria,47F0Z@766|Rickettsiales	766|Rickettsiales	P	domain protein	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158357_k127_942752_0	391896.A1I_06415	1.237e-146	469.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,47F1N@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158357_k127_942752_3	1031288.AXAA01000001_gene2337	1.711e-10	62.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,36DRA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158357_k127_946342_0	336407.RBE_0162	3.234e-313	968.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,47EXC@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158357_k127_946342_13	913325.N799_08865	6.653e-05	54.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1X5HS@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
SRR25158357_k127_946342_5	391896.A1I_06155	1.108e-79	278.0	COG0545@1|root,COG0545@2|Bacteria,1RAV0@1224|Proteobacteria,2UYE2@28211|Alphaproteobacteria,47G9B@766|Rickettsiales	766|Rickettsiales	O	protein peptidyl-prolyl isomerization	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
SRR25158357_k127_946342_4	1236908.wNo_02290	1.991e-159	521.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,47EUN@766|Rickettsiales	766|Rickettsiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158357_k127_946342_7	334545.CCMG01000018_gene1483	4.426e-47	177.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria,47FMM@766|Rickettsiales	766|Rickettsiales	Q	Protocatechuate 3,4-dioxygenase beta subunit	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158357_k127_946342_8	391896.A1I_03485	6.321e-40	153.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,47FMI@766|Rickettsiales	766|Rickettsiales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158357_k127_946342_3	391896.A1I_03490	1.473e-186	595.0	COG0195@1|root,COG0272@1|root,COG0195@2|Bacteria,COG0272@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,47EVY@766|Rickettsiales	766|Rickettsiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SRR25158357_k127_946342_1	86106.I862_00900	6.13e-232	741.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,47F21@766|Rickettsiales	766|Rickettsiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
SRR25158357_k127_946342_9	293613.A1E_03165	3.211e-31	126.0	COG0858@1|root,COG0858@2|Bacteria,1PRXZ@1224|Proteobacteria,2V45H@28211|Alphaproteobacteria,47FSW@766|Rickettsiales	766|Rickettsiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158357_k127_946342_6	315456.RF_0620	3.528e-53	194.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,47FCY@766|Rickettsiales	766|Rickettsiales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158357_k127_946342_11	644107.SL1157_0518	9.045e-11	63.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_946342_10	5722.XP_001329797.1	1.114e-11	79.0	COG0666@1|root,KOG0510@2759|Eukaryota	2759|Eukaryota	Z	temperature-gated cation channel activity	-	-	-	ko:K15502,ko:K15503,ko:K15504	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,DUF3447,zf-MYND
SRR25158357_k127_946342_2	1122135.KB893171_gene2026	4.054e-204	650.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA helicase	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR25158357_k127_952039_2	336407.RBE_0723	1.925e-74	256.0	COG2807@1|root,COG2807@2|Bacteria,1QW3Y@1224|Proteobacteria,2TXEA@28211|Alphaproteobacteria,47GTV@766|Rickettsiales	766|Rickettsiales	P	transmembrane transport	ampG1	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR25158357_k127_952039_0	334545.CCMG01000007_gene349	4.208e-145	473.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2UG5N@28211|Alphaproteobacteria,47FWV@766|Rickettsiales	766|Rickettsiales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158357_k127_952039_1	1333998.M2A_1668	2.449e-92	310.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,4BQUU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158357_k127_964495_4	315456.RF_0479	4.19e-56	203.0	2DBAU@1|root,2Z84H@2|Bacteria,1N4IT@1224|Proteobacteria,2UCMU@28211|Alphaproteobacteria,47GQY@766|Rickettsiales	766|Rickettsiales	S	Putative phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_964495_1	315456.RF_0413	1.131e-175	561.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,47F20@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX2	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158357_k127_964495_3	1105110.MC5_06965	1.166e-58	212.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,47FIC@766|Rickettsiales	766|Rickettsiales	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158357_k127_964495_0	293613.A1E_01890	7.833e-222	707.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,47EZA@766|Rickettsiales	766|Rickettsiales	L	ATP-dependent DNA helicase (RecG)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158357_k127_964495_7	1123389.ATXJ01000004_gene1153	5.215e-42	162.0	COG1738@1|root,COG1738@2|Bacteria,1WIRJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158357_k127_964495_2	293614.A1C_06475	4.272e-87	295.0	COG1073@1|root,COG1073@2|Bacteria,1R8S6@1224|Proteobacteria,2U8I8@28211|Alphaproteobacteria,47G6Y@766|Rickettsiales	766|Rickettsiales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	FSH1
SRR25158357_k127_964495_6	1547437.LL06_07730	2.566e-52	188.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,43HR1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158357_k127_964495_5	1105110.MC5_01340	1.667e-53	189.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,47EXC@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158357_k127_974295_10	876269.ARWA01000001_gene2626	1.121e-31	124.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,3N9SI@45404|Beijerinckiaceae	28211|Alphaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158357_k127_974295_11	1249480.B649_09765	3.197e-13	72.0	2EFVT@1|root,339N0@2|Bacteria,1NGTP@1224|Proteobacteria,431SW@68525|delta/epsilon subdivisions,2YS5A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158357_k127_974295_2	244581.IM40_01270	1.821e-142	471.0	COG2860@1|root,COG2860@2|Bacteria,1QVY0@1224|Proteobacteria,2UB1W@28211|Alphaproteobacteria,47F2R@766|Rickettsiales	766|Rickettsiales	S	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,UPF0126
SRR25158357_k127_974295_0	272951.rsib_orf657	0.0	1258.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,47EVZ@766|Rickettsiales	766|Rickettsiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158357_k127_974295_9	357244.OTBS_0168	1.551e-33	133.0	COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria,47FQM@766|Rickettsiales	766|Rickettsiales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158357_k127_974295_1	336407.RBE_1256	5.182e-155	505.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,47F33@766|Rickettsiales	766|Rickettsiales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158357_k127_974295_3	336407.RBE_1255	1.577e-120	391.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,47EXU@766|Rickettsiales	766|Rickettsiales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158357_k127_974295_7	315456.RF_1133	2.584e-60	216.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,47F9P@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158357_k127_974295_8	293613.A1E_00760	1.194e-42	160.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,47FN0@766|Rickettsiales	766|Rickettsiales	S	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158357_k127_974295_6	272947.RP150	7.239e-62	221.0	COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2UDVW@28211|Alphaproteobacteria,47FIQ@766|Rickettsiales	766|Rickettsiales	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	yqiX	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158357_k127_974295_4	293613.A1E_05425	1.024e-112	372.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,47ETZ@766|Rickettsiales	766|Rickettsiales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158357_k127_974295_5	315456.RF_1340	1.143e-87	297.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,47F56@766|Rickettsiales	766|Rickettsiales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
## 1075 queries scanned
## Total time (seconds): 6.907549619674683
## Rate: 155.63 q/s